Essential Metabolites of M. tuberculosis and their Molecular Mimics

Gyanu Lamichhane1, Joel S. Freundlich2, Sean Ekins 3, 4, 5, 6,, Niluka Wickramaratne1, Scott Nolan1, William R. Bishai1

1Johns Hopkins School of Medicine, Department of Medicine, 1550 Orleans St, Room 103, Baltimore, MD 21287; 2Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843-2128;3Collaborative Drug Discovery, 1633 Bayshore Highway, Suite 342, Burlingame, CA 94403; 4 Collaborations In Chemistry, 601 Runnymede Avenue, Jenkintown, PA 19046; 5 Department of Pharmaceutical Sciences,

University of Maryland, Baltimore, MD, USA; 6 Department of Pharmacology, Robert Wood Johnson Medical School, University of Medicine & Dentistry of New Jersey, Piscataway, New Jersey 08854, USA.

Acknowledgements: GL and WRB acknowledge support of NIAID grants AI 30036, AI 37856, AU 79590, and AI 36973. The CDD TB database along with introductory training is provided freely to Mtb researchers through October 2010 thanks to funding from the Bill and Melinda Gates Foundation (Grant#49852). SE gratefully acknowledges Accelrys Inc. for providing Discovery Studio.