EXPANDED NEWBORN EXPANDED NEWBORN SCREENINGSCREENING ::

The Mississippi State The Mississippi State Department of Health Department of Health

ExperienceExperience(MSDH) (MSDH)

Early 1980Early 1980SPRANS Grants for statewide Newborn SPRANS Grants for statewide Newborn

Screening of Phenylketonuria &Screening of Phenylketonuria &HypothyroidismHypothyroidism

Law mandating statewide Newborn Law mandating statewide Newborn Screening of PKU & HypothyroidismScreening of PKU & Hypothyroidism

Newborn Screening Fee charged to each Newborn Screening Fee charged to each hospital for each newborn ($2.50) hospital for each newborn ($2.50)

Newborn Screening FeeNewborn Screening Fee(One of the first states to charge a fee for newborn (One of the first states to charge a fee for newborn

screening)screening)

Lab test costs Lab test costs

$$$$$$$$$$$$ $$$$$$$$$$$$

FollowFollow--up costs up costs

$$$$$$$$$$$$$$$$$$$$$$$$$$

Mississippi Mississippi State State MapMap

Late 1980Late 1980’’s and 1990s and 1990’’ss

Newborn Screening Education for Newborn Screening Education for each delivering hospital and Health each delivering hospital and Health Department was started.Department was started.

Hemoglobinopathies, Galactosemia, Hemoglobinopathies, Galactosemia, & Homocystinuria were added to the & Homocystinuria were added to the law mandating newborn screening.law mandating newborn screening.

MississippiMississippi’’s Newborn Screening s Newborn Screening Program in the year 2000Program in the year 2000

In the year 2000, a two and a half In the year 2000, a two and a half year old male child died of Mediumyear old male child died of Medium--Chain AcylChain Acyl--CoA Dehydrogenase CoA Dehydrogenase Deficiency (MCAD) in a small, north Deficiency (MCAD) in a small, north Mississippi town. His name was Ben Mississippi town. His name was Ben Haygood.Haygood.

MississippiMississippi’’s Law in the year 2001s Law in the year 2001

The bill that was passed by the legislature and The bill that was passed by the legislature and signed into law by the governor required: signed into law by the governor required:

Development of a pamphlet by MSDH Development of a pamphlet by MSDH Advisory Committee about supplemental Advisory Committee about supplemental newborn screening tests;newborn screening tests;

Information to be given to expectant mothers Information to be given to expectant mothers before and after birth by their physician.before and after birth by their physician.

2002 Expanded Newborn 2002 Expanded Newborn Screening LawScreening Law

The law as it stands today is know as the The law as it stands today is know as the ““Ben Haygood Comprehensive Newborn Ben Haygood Comprehensive Newborn Screening Act.Screening Act.””

The MSDH shall establish, maintain and The MSDH shall establish, maintain and carry out a comprehensive newborn carry out a comprehensive newborn screening tests to be specified by the screening tests to be specified by the Mississippi State Board of Health upon the Mississippi State Board of Health upon the advice and recommendations of the MSDH advice and recommendations of the MSDH Genetic Advisory committee.....Genetic Advisory committee.....

The 2002 Law Resulted in the The 2002 Law Resulted in the Following:Following:

A total of 40 newborn disorders/ A total of 40 newborn disorders/ conditions to be screenedconditions to be screened

A total charge of $ 70.00 per newborn A total charge of $ 70.00 per newborn screened ($ 1.75 per test)screened ($ 1.75 per test)

A three member child health team in each A three member child health team in each of the nine districts of the state (a nurse, of the nine districts of the state (a nurse, a social worker and a clerk) to case a social worker and a clerk) to case manage children with abnormal newborn manage children with abnormal newborn screening results.screening results.

11stst Year of Mandated Expanded Newborn Year of Mandated Expanded Newborn Screening In MississippiScreening In MississippiApproximately 42,201 Approximately 42,201

June 1, 2003 June 1, 2003 –– May 31, 2004May 31, 2004

Cystic FibrosisCystic Fibrosis 77Biotinidase DeficiencyBiotinidase Deficiency 44MCADsMCADs 33TyrosinemiaTyrosinemia 11Sickle Cell DiseaseSickle Cell Disease 7070Congenital HypothyroidismCongenital Hypothyroidism 2121GalactosemiaGalactosemia 99PKUPKU 11