farmasi praktis obj.3

8/16/2019 Farmasi Praktis Obj.3

1/20

K E L O M P O K I I IK H A I R I N I S A S E P T I A N A 1 3 11 0 11 0 1 5N A F I L ATA I N I 1 3 11 3 11 0 1 9M O N I C H A P U S P I TA S A R I 1 3 11 0 11 0 2 0M O L I N D A D A M R I S 1 3 11 0 11 0 2 1S A R D E F I TA L O K A 1 3 11 0 11 0 2 3

FARMASI PRAKTIS 1


2/20

EQUIPMENT THAT IS USUALLY USED IN DRUGCOMPOUNDING

Tools drug compounding! drug sc l"s

#! mor$ r nd s$ mp"r

c! c psul" %illing m c&in" $ools no$d! gl ss $ools"! spoon' pip"$$"' sp $ul ' %unn"l%! drip p n

g! #o rd pill' si"(ing


3/20

)EIGHTS

*

Sc l"s m"dicin" $&"r" r" + $,p"s' n m"l,-

.! Sc l"s roug&- $&" po/"r lo d o% 012 gr ms $o .222 gr mss"nsi$i(i$, o% 022 mg0! Sc l"s gr m su#$l"- $&" po/"r lo d o% .22 gr ms $o 022 gr mss"nsi$i(i$, 12 mg+! Sc l"s milligr ms- po/"r lo d o% .2 gr ms $o 12 gr mss"nsi$i(i$, o% 1 mg!

Lo d po/"r- $&" m 3imum /"ig&$ $& $ m , #" /"ig&"d!S"nsi$i(i$,- $&" m 3imum r"4uir"d ddi$ion l /"ig&$ on on" pl $" sc l"s'

%$"r #o$& %ill"d $o m 3imum lo d' c using $&" n""dl" s/ing $&" sc l"s o%no$ l"ss $& n 0 mm p"r dm long n""dl"s!


4/20

D"scrip$ion -.!P p n grounding sc l"s0!Tom#ol r"gul $ing $&" "s$ #lis&m"n$"r"c$ sc l"s

+!An$ing poin$"r up&olding $&" sc l"s5spiri$ l"("l67!8 rum sc l"s1!S9 l:!Tu s $&" #u%%"r sc l"s;!Pis u middl" < c"n$"r 9ni%"=!Pis u & nd>!T ng n sc l"s.2!S"l"c$ion 9",s < nu$s r"gul $or o% $&"

# l nc"..!Piring sc l"s


5/20

)"ig&ing

.! C&"c9 /&"$&"r ll $&" compon"n$s o% $&" sc l" < # l nc" is ppropri $" in pl c"' #, m $c&ing $&"num#"rs con$ in"d in $&"s" compon"n$s 5s"" %igur"6!

0! C&"c9 $&" posi$ion o% $&" sc l"s is lign"d < %l $' i$c n #" s""n %rom $&" posi$ion o% " rrings 5+!.6 /i$& $&" # s" ring 5+!06 $o #" pr"cis"! I% i$ is no$ rig&$ /" $urn$&" 9no# 506!


6/20

+! Onc" g in /" c&"c9 /&"$&"r $&" posi$ion o% $&" #l d" 5;6 nd 5=6 r" lr" d, in pl c"! I% i$ is $&"n $&"l"("r 5:6 /" li%$ or ro$ $" i$ $imm# ng n #" li%$"d nd

9 n9"li& $ n /&"$&"r &is pl $" # l nc"d or #i s"d!I% no$ # l nc"d /" c n ro$ $" $&" nu$ 5.26 l"%$ or rig&$ccording $o $&" # l nc"' so $& $ # l nc" # l nc"d!

7! A%$"r $& $ /" ?us$ pu$ $&" p rc&m"n$ p p"r o("r #o$& pl $"s sc l"s' li%$ l"("r 5:6 $o c&"c9 /&"$&"r $&"sc l"s & (" #""n # l nc"d! )&"n ,ou r" # l nc"d'$&"n /"ig&ing $&" m $"ri ls c n #"gin!


7/20

1! Ho/ /"ig&ing ingr"di"n$s-! Solid m $"ri ls suc& s po/d"rs' c ndl"s' "$c! /"ig&"d

on p rc&m"n$ p p"r!

#! @ solid m $"ri ls suc& s p"$rol"um ?"ll,' d"ps' /"ig&"d on p rc&m"n$ p p"r or #o(" $&" ( pori "r cup!

c! T&" mol$"n m $"ri l c n #" /"ig&"d on / $c& gl ss'cup ( pori "r or dir"c$l, in$o $&" #o$$l" or con$ in"r!


8/20

d! Biscous li4uid m $"ri ls suc& s "9s$ 9 #"ll don nd"3$r c$ &iosi mi dir"c$l, /"ig&"d' /&il" %or ic&$iol /"ig&"d on p p"r p rc&m"n$ pr"(iousl, sm" r"d

/i$& li4uid p r %%in < p"$rol"um ?"ll,!

"! O3idi ing m $"ri ls 59 lii p"rm ng n s' iodin"' Arg"n$i ni$r s6 /"ig&"d on $&" gl ss"s /"ig& on $&"

/ $c& gl ss or clos"d!%! & n /&o /"ig&"d l"ss $& n 12 mg dilu$ion


9/20

DASAR PERHITUNGAN DOSIS

.! "r $ d n d"ng n m"nim# ng p"ndug n m"l lui ling9 r d d 5p d s pi6

0! Umur c $ $ n l &ir' rumus gigi d n $ ndu9

+! on("rsi Dosis m nusi 9" &"/ n


10/20

TOOLS TO MEASURE THE BOLUME

. ! T&" m" suring cup is us"d $om" sur" $&" li4uid $o #"

m d" or li4uid $o #" $ 9"n!


11/20

0! Erl"nm","r us"d %or dissol(ingm $"ri ls /i$& s& 9"n or di9oco9d nus"d $o g ug" 5$&" l"("l o% ccur c,l"ss6!


12/20

COMPOUNDING TOOLS AND EQUIPMENT OTHER GLASS

.! Mor$ r mor$ r nd p"s$l" or s$ mp"r' us"d $o grind nd mi3 $&"ingr"di"n$s $og"$&"r!

0! T&" spoon c n #" us"d $o $ 9" $&" solid m $"ri l o% $&" #o$$l"' $&"li4uid m $"ri l c n #" us"d %or pip"$$" or dir"c$l, pour"d c r"%ull,' /&il" %or s"mi solid m $"ri l 5cond"ns"d "3$r c$ nd % $s6 c n #" us"dsp $ul < sp $ul !

+! Sudip %rom %ilm < mic us"d $o uni%,' cl" ning po/d"rs or oin$m"n$snd pu$ in $&" con$ in"r!


13/20

7! T&" ( pori "r cup 5porc"l in6 us"d $o /"ig& con$ in"rs' $o"( por $" or dr in %luid' m"rg" or mi3 mor" $& n on"m $"ri l!

1! Gl ss"s / $c&"s nd /"ig&ing #o$$l" $o /"ig& $&" (ol $il"m $"ri l' su#lim"' nd li4uids $& $ c n no$ #" /"ig&"d /i$&p rc&m"n$ p p"r!

:! T&" po$ in%usion $o m 9" in%usion solu$ions!

;! T&" o rd o% pills us"d $o /r p $&" pill' cu$ pills' $&"nround"d #, rounding pills!


14/20

=! si"(ing "4uipm"n$ us"d %or si%$ing $&" m $"ri lccording $o $&" d"gr"" o% %in" po/d"rs!

>! Funn"ls us"d $o %il$"r /i$& %il$"r p p"r l id on %il$"rp p"r %unn"l round cu$ o% ppro3im $"l, . cm #"lo/ $&"sur% c" o% $&" %unn"l!

.2! Rod s$irr"r

..! T&" c psul" %il$"r


15/20

drip p n- $o %il$"r $&" con$"n$ o% crud" drug


16/20

Ano$&"r Tools

! gr m # l nc"- $o # l nc" $&" l"("ls o% drug #! milligr m # l nc"- $o # l nc" $&" l"("ls o% $&" drug

in po/d"r p"nim#ng n milligr ms!

c! mor$i- mi3ing drug < drug grind /i$& con$"n$ $& $& s #""n s"$!d! S$ mp"r- $ool $o grind $&" drug so "("nl, mi3"d!


17/20

! / $"r# $&- $o produc" s$" m $o m"l$ solid dos g" # sis /&"r" $&" pr"p r $ion is pl c"d on $&"&o$pl $"

#! sond"- &os" $o pu$ %ood in $&" %orm o% li4uidc! d"sicc $or- $o #sor# mois$ur"d! n l,$ic l # l nc"- $o /"ig& drugs $& $ /"ig&s l"ss

$& n . gr m


18/20

! sp"c$rop&o$om"$"r Sp"c$ro $ool $o do $& $ is n n l,sism"$&od $& $ is # s"d on $&" #sorp$ion o%"l"c$rom gn"$ic r di $ion $o d"$"rmin" $&" 4u n$i$, o% su#s$ nc" /&ic& is ("r, sm ll

#! HPLC 5HPLC6 dg c&rom $ogr p&, mo#il" p& s" is li4uid nd $&" s$ $ion r, p& s" li4uid < solids $o m" sur"l"("ls o% su#s$ nc" # s"d on di%%"r"nc"s in pol ri$,

c! PH m"$"r $o m" sur" $&" cidi$, o% su#s$ nc"d! H rdn"ss $"s$"r $ool $o m" sur" $&" & rdn"ss o% $ #l"$s"! Fri #ili$i $"s$"r $ool $o m" sur" $&" %r gili$, $ #l"$


19/20

! Disin$"gr $i2n $"s$"r $ools $o m" sur" $ #l"$ disin$"gr $ion $im" #! DissoluTi2n $"s$"r $ool $o m" sur" $&" solu#ili$, o% $&" $ #l"$c! Singgl" punc& $ #l"$ pr"ss $ool $o m nu ll, prin$ $ #l"$d! Fum" $o s$or" $&" su#s$ nc" $& $ $&" l"("l o% cidi$, or &ig& l"("ls

5"3- m"$& nol6"! Au$o9l % Tool %or m"ns$r"ril9 n gl ss or ru##"r m $"ri l using

pr"ssur"%! n lg"sim"$"r $ool $o g"n"r $" p in s$imuli 5%or nim ls6g! Po$"nsiom"$ri Is n n l,sis m"$&od # s"d on m" sur"m"n$s o% c"ll

po$"n$i l di%%"r"nc" o% c"ll l"9$ro9imi < on" m"$&od o%d"$"rmining $&" conc"n$r $ion o% su#s$ nc" #, m" suring $&"po$"n$i l ( lu"


20/20

THANK’S

farmasi praktis obj.3

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