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Feasibility study of TULIP: a TUrningLInac for ProtontherapLInac for Protontherapy

ICTRICTR--PHE 2012 ConferencePHE 2012 Conference

28.02.2012A. Degiovanni

U. Amaldi, M. Garlasché, K. Kraus, P. Magagnin, U. Oelfke, P. Posocco, P. Riboni, V. Rizzoglio

TULIP: a Single Room Facility projectTULIP: a Single Room Facility project

Why single room facilities ?– Proton therapy beneficial to at least 12% of X-ray patients

(ENLIGHT studies outcome)(ENLIGHT studies outcome)– ~ 2.400 patients/year every 10'000'000 people– 1 proton room every 1.5 Milion inhabitantsp y

Advantages– Spread the investement cost– Hospital based protontherapy (not dedicated centres)

Technical challengesSize and cost of the machine– Size and cost of the machine

– Dose delivery modalities– Treatment time

28.02.2012 ICTR-PHE 2012 - A. Degiovanni 2

A A cyclinaccyclinac basedbased solutionsolution

TULIP = TU i LI f C-band linac

C-band linacSection 1TUrning LInac for

Protontherapy

C band linacSection 2

Section 1

cyclotron

Line with 2% momentum acceptancey acceptance

B d

RF rotating joints

Beam dose delivery

RF Power sources

Mechanical structure


The CYCLINAC timelineThe CYCLINAC timeline

1993: first Cyclinac proposalproposal

2007: first * See abs. #227 by S. Verdú Andrés

2003: test on LIBO-62 MeV (TERA-CERN-INFN)

CABOTO design

2010:2010: CABOTO-C design (*)

11.2010: LIGHT 1st UNIT inaugurated by

CERN DG Prof. R. Heuer(courtesy of ADAM SA ) [U Amaldi S Braccini and P Puggioni


ADAM SA.) [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) 111-131]

The The linaclinac and RF systemand RF systemElectric field di t ib ti (HFSS)

acc. cell on axis

coupl. cellon side

distribution (HFSS)

acc. tanksexcited cavity

TANKspace for quadrupoles

un-excitedcavity

RF cavities in π/2 mode Accelerating TANKS Acc. units with space for PMQs H11 polarizer (Igor Syratchev, CERN) linear

l i ticircular l i ti


polarization polarization

The CYCLINAC timelineThe CYCLINAC timeline

1993: first Cyclinac proposalproposal

2007: first * See abs. #227 by S. Verdú Andrés

2003: test on LIBO-62 MeV (TERA-CERN-INFN)

CABOTO design

2010:2010: CABOTO-C design (*)

11.2010: LIGHT 1st UNIT inaugurated by

E0 = 15 MV/m

CERN DG Prof. R. Heuer(courtesy of ADAM SA ) [U Amaldi S Braccini and P Puggioni

E0 = 16 MV/m


ADAM SA.) [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) 111-131]

The choice of the frequencyThe choice of the frequency

TULIP project requires shorter linacsp j q Higher gradients are needed (~35 MV/m)

Reliability in terms of BDR High gradient tests (S- and C- band) in collaboration with CLICcollaboration with CLICsee poster #203 (Cyclinac group)

Size of RF rotating joints for power transmissionp

Power source availability

CC-- band : 5.712 GHzband : 5.712 GHz


TULIP preliminary designTULIP preliminary design

@5.7 GHz (C-band) from 35 to 210 MeV

Quantity [unit] Section 1 Section 2

Output energy [MeV] 80 210

Total length [m] 3.9 5.9g [ ]

Avg. E0 [MV/m] 20-24 32-38

Max. ESURFACE [MV/m] 150 170

Number of units 1 (4) 7

Peak Power [MW] 25 84

Repetition rate [Hz] 200 200Repetition rate [Hz] 200 200

Pulse length [μs] 2.5 2.5


Fast active energy variationFast active energy variation

E)(E

) / N

(EdN

(

Energy [MeV]


FastFast active active energyenergy variationvariation

Active energy variation in the range 80-210 MeV Energy spread within 2 mm distal fall-off

Active spot scanning with Active spot scanning with tumourtumour multipaintingmultipainting


TULIP TULIP beambeam transfertransfer lineline

pER

5381With Δp/p = ±2% ΔR/R = ± 7%

pER 5.38.1

For R = 30 cm ΔR = ± 2.1 cm

30 5

28.2 32.9 29.4 cm

31.7 cm

30.5 cm

cm cm


Supporting structureSupporting structureC-band

linaclinac

Section I [kg]

Section II [kg]

Linac 340 460Linac 340 460Beam

Structure 3400 4800

Ancillaries 640 860


TULIP Mechanical DesignTULIP Mechanical DesignBearings

Rot axisRot. axis

Actuators

1 2 31 3

Total estimated 60weight [tons] 60

Max angacceleration 0.5acceleration

[rad/s2]0.5

Max rotation speed* [rpm] 1.5


speed [rpm]* derived from norm EN 60601 and max vel considerations

NovelNovel studystudy of of dynamicdynamic dose dose deliverydelivery

• simulation of dynamic delivery via computer software• based on treatment plan data for a static dose delivery• dynamic parameters (repetition rate, vGantry , vCouch)

Plan data:Dij matricesij

Spot positionsSpot weights

Dynamic dose l l ti

Dose di t ib ti

TPS:Calculation of

Tulip machineparameters:Gantry speed

calculation distributionstatic plan

yRepetition rateCouch speed

Number of protons

more information: Poster 156 by Kim Kraus (DKFZ Heidelberg) more information: Poster 156 by Kim Kraus (DKFZ, Heidelberg)


NovelNovel studystudy of of dynamicdynamic dose dose deliverydelivery• dynamic dose delivery to a cylindrical target volumecylindrical target volume

• different combinations of dynamic parameters

the higher the gantry speed thethe higher the gantry speed the higher must be the repetition rate

to deliver all spots

DDiff = Ddyn(f= 100Hz, vGantry = 1°/s) - Dstatic

Difference dose distribution :Good agreement of the dynamic

and static dose distributions within the target!

28.02.2012

within the target!

ICTR-PHE 2012 - A. Degiovanni 15

SummarySummary

First design in C-band for a single room facility:

Linac and RF design M h i l d i

Cyclinac Mechanical design Novel dose delivery

concept

Future developments:Optimization of Section 1 TULIP New dose

deliveryCompact beam line- Optimization of Section 1

- Final mechanical spec.

de e ybeam line

Combine acceleration Combine acceleration d t fl ibilit ithd t fl ibilit ith

New mechanical

designand gantry flexibility with and gantry flexibility with active energy variationactive energy variation

g


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