february, 2002 genetics 453 evolutionary genetics...
TRANSCRIPT
February, 2002Genetics 453
Evolutionary Genetics
Chromosome Rearrangements
Joe Felsenstein
Department of Genome SciencesUniversity of Washington, Seattle
email: [email protected]
Chromosome Rearrangements
Inversion Translocation Transposition Tetraploidy
Additional question: when these occur they are
rare in a population: how do they spread?
plate
hot spot
Formation of the Hawaiian Islands
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A Paracentric Inversion
A Pericentric Inversion
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A translocation
Before
After
Breaks
Rearrangement
at first division of meiosis metaphase
EFGHIJ
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CD
NOP KLM
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A translocation heterozygote
pairs with a pair of untranslocated chromosomes
A pair of translocated chromosomes�
Barriers between mating of polyploids and euploids
gametes
triploid offspring
a tetraploid an ordinary diploid
gametes
the resulting aneuploid offspring
This freeware-friendly presentation prepared with
• Linux (operating system)
• PDFLaTeX (mathematical typesetting and PDF preparation)
• Idraw (drawing program to modify plots and draw figures)
• Adobe Acrobat Reader (to display the PDF in full-screen mode)
(except that we had to use Microsoft Windows to project this as the Xserver I have in Linux is not too great)