first year - i semester 4 0+0+4 120 ugd100112...study program: medical laboratory technicians code...

Study Program: MEDICAL LABORATORY TECHNICIANS

Code

FIRST YEAR - I SEMESTER

COURSE Credits Hours Overall workload

3MF100212 Anatomy 7 3+3+1 210

Introduction to human genetics 5 2+2+1 150

Histology and Embryology 6 2+3+1 180

Communication skills 6 2+3+1 180

Clinical phychology 2 1+1+1 60

UGD100112

Foreign language 1 – English

Foreign language 1 – Italian

Foreign language 1 – German

Foreign language 1 – French

Foreign language 1 – Spanish

Foreign language 1 – Russian

4

0+0+4

120

UGD102712 Sports and recreation* 0 0+0+2

0

Code

FIRST YEAR - II SEMESTER


Physiology 4 2+1+1 120

Biochemistry 4 2+1+1 120

Microbiology and Parasitology 6 2+3+1 180

Nursing care 6 2+3+1 180

Ecology and Hygiene 2 2+0+1 60

Epidemiology 4 2+1+1 120

Computer Science 4 2+1+1 120

Code

SECOND YEAR – III SEMESTER


Pathophysiology 6 2+3+1 180

Pathology 6 2+3+1 180

Pharmacology 4 2+1+1 120

Introduction to internal medicine 6 3+2+1 180

Immunology 3 1+1+1 90

Cell biochemistry 5 2+2+1 150

Code

SECOND YEAR - IV SEMESTER


Good laboratory practice 5 2+2+1 150

Analytical chemistry 5 2+2+1 150

Introduction to transfusiology 5 2+2+1 150

Medical histology 4 2+1+1 120

Biostatistics 4 2+1+1 120

Instrumental analysis 5 2+2+1 150

Elective course group 1 2 2+0+1 60

Code

THIRD YEAR – V SEMESTER


Introduction to clinical practice 5 2+1+1 150

Introduction to infectious diseases 5 2+2+1 150

Clinical and toxicological analyses 6 3+2+1 180

Bromatology 6 3+2+1 180

Laboratory safety 4 2+1+1 120


Code

THIRD YEAR - IV SEMESTER


Clinical microbiology 4 1+2+1 120

Clinical biochemistry 6 3+2+1 180

Clinical tranfusiology 4 1+2+1 120

Professional practice 4 0+4+0 120


Bachelor thesis 8 240

LIST OF ELECTIVE COURSES

Code

SECOND YEAR – IV SEMESTER (Group 1)


Nutritionism-modelling and

optimization

2 2+0+1 60

Public health 2 2+0+1 60

Intrahospital infections 2 2+0+1 60

Code

SECOND YEAR –V SEMESTER (Group 2)


Virusology 4 2+1+1 120

Methodology of scientific research

in Health Care

4 2+1+1 120

Nuclear medicine 4 2+1+1 120

Code

THIRD YEAR- VI SEMESTER (Group 3)


Citological analysis in early

diagnostics of malignant diseases

4 2+1+1 120

Immunological laboratory

techniques

4 2+1+1 120

Evaluation of instruments, methods

and reagents

4 2+1+1 120

COURSE PROGRAMME INFORMATION IN ACCORDANCE WITH ARTICLE 4 FROM

THE REGULATIONS BOOK FOR COMPULSORY COMPONENTS OF THE COURSE

PROGRAMMES FROM THE FIRST, SECOND AND THIRD CYCLE STUDIES

Annex No.3 Course Programme- first/second/third cycle studies

1. Course title Anatomy

2. Code

3. Study programme Medical laboratory technicians

4. Organizer of the study programme(unit or

institute, faculty, department)

Faculty of Medical Sciences

University "Goce Delchev" Stip

5. Level of studies (first, second and third

cycle)

First cycle

6. Academic year / semester First 7. Number of

credits

7

8. Lecturer/ Instructor Prof. Svetlana Jovevska PhD

9. Required prerequisite courses

10. Course objectives (competencies):

Introduction to anatomy as morphological science, mastering of professional

terminology, complete study of the locomotion system extremities.Introduction to the

anatomy of the chest, abdomen and pelvis, and skeletotopical and holotopical ratios in

these physical bodies gaps.

11. Course content:

Theoretical instruction

1. Introduction to osteology and anatomy, types of bones, bone components, technical

terminology. Bones of fixed and movable part of the upper limb bones of fixed and

movable part of the lower limb, chest bone and body.

2. Introduction to sindezmology, wrist, components of the joint, types of joints.

Syndezmology of the upper limb, Syndezmology of the trunk and lower limb

3. Miology, Angiology and Neurology of the upper limb. Miology, Angiology and

Neurology of the lower limb.

4. Orientacion of bone fracture, spatula, upper arm, forearm bones (radius and ulna)

Idowu chest, breast structure, the system of organs for breathing, cardiovascular

organs. Abdominal wall muscle, vasculature, innervation, ratios.

5.Organs in the abdominal cavity-peritoneum, esophagus, stomach, organs in the

abdominal cavity-small and large intestine, liver, bile tract, pancreas

6.Spleen, kidney, adrenal gland, urinary tract, pelvic cavity-limits and construction;

urinary organs, female sex organs, male sex organs

7. Arteries of the head and neck, veins and lymph vessels in the head and neck

8. Cranial nerves-number nomenclature, proportions, cranial nerve-inervation areas

9.Organs in the head and neck-topography ratios, endocrine glands.

10. Organs of the digestive system in head and neck organs of the respiratory system

in head and neck.

11. Sensory organs, eye and ear, nervous system, construction, types of nerve fibers

division of the nervous system, ventricular system

12. Spinal cord, rombest brain, midbrain, membranes of the brain.

Practical instruction

1.Orientation of bone fracture, spatula, upper arm, forearm bones (radius and ulna)

Skeleton of hand: (bunch of hand), hands bones and bones of the fingers, chest and

spine, joints of the lower limb, Gaza pelvic-bone, joints of coxae and sacrum bone

skeleton of above the knee-femora, and shin-bones of tibia, fibula, patelae.

2. Skelet foot-bones of the foothill, knee and toes, joints of the upper extremity, chest

and spine, lower extremity joints, muscles, and blood vessels of the upper limb.

3. Muscles and blood vessels of the lower limb, innervation of upper and lower

extremity, chest-wall construction, division of mediastinum, borders, composition,

topography, Mediastinal organizational relationships; structure and topography of the

respiratory system.

4. Anatomy of the system for blood-heart and major blood vessels, and topography

ratios, abdominal wall-building: muscle ratios of muscle organs, vasculature and

innervation, orientation in the abdominal cavity-peritoneum, esophagus, stomach, and

topography ratios.

5.Topography of the organs in the abdominal cavity-structure and orientation of the

small and large intestine, orientation models of liver, bile tract, pancreas, orientation

models of spleen, kidney, adrenal gland, urinary tract anatomy.

6.Pelvic wall construction, topographic relationships of organs, pelvic organs, pelvic

cavity-urines authorities, relations with other organs, vascularization and innervation,

female genital-orientation, relations with other organs, male sex organs-orientation,

relations with other authorities.

7. Vasculature of the head and neck, venous, lymphatic system of the head and neck

8. Spinal nerves, mouth

9. Organs of the digestive system located in the head and neck, respiratory organs

situated in the head and neck.

10. Nasal cavity-anatomical parts, structure, function, endocrine glands-topography

ratios.

11. Eye-anatomy, proportion, anatomy of the orbit, ear-anatomy, relationships with

other agencies.

12. Senses of taste, smell, touch and balance, autonomic nervous system-anatomical

division function.

12. Course methodology:Interactive classes, individual consultations with students

13. Total available time 7 ECTS х 30 hours = 210 hours

14. Distribution of available time 45+45+15+ 15+90

15. Forms of teaching activities 15.1. lectures / theoretical

teaching,

e-teaching

45 hours

15.2. theoretical and practical

exercises,

e-exams, seminars, team

work

45 hours

16. Other forms of activities 16.1. Project work 15 hours

16.2. Individual work 15 hours

16.3. Homework 90 hours

17. Assessment method

17.1. Tests / oral exams 70 points

17.2. Seminar paper / project (presentation: written and/or 10 points

oral)

17.3. Attendance and participation 20 points

18. Grading system (points / grade) up 50 points 5 (five) (F)

51 to 60 points 6 (six) (E)

61 to 70 points 7 (seven) (D)

71 to 80 points 8 (eight) (C)

81 to 90 points 9 (nine) (B)

91 to 100 points 10 (ten) (A)

19. Signature and final exam

prerequisites

Attendance- at least 7 (60%) continuous checks

at lectures and 10 tutorials, for final exam scored

42 points and passed continuous checks.

20. Language of instruction Macedonian language

21. Method of monitoring the quality of

instruction

Self-evaluation

22.

Literature

22.1.

Required literature

No. Author Title Publisher Year

1. Prof.dr.Shumanov et al. Anatomy of man-script educational

work

2. A. Kargovska-Klisarova,

N.. Djordjevic, D..

Lazarova

Anatomy of man-

Osteologija

educational

work

3. A. Kargovska-Klisarova

A. Kargovska-

Klisarova

A.Kargovska-Klisarova,

Anatomy of human-arm

and chest

Anatomy of man-Foot

Anatomy of man-

MD. Dzhidrova, A.

Strateska-Zafiroska

N.. Christ-Djordjevic, A..

Kargovska-Klisarova

Abdomen

Anatomy of man-Pelvis

22.2.

Supplementary literature


1. Sinelnikov Anatomical Atlas of

man (I, II, III part)

2. F.N. Netter Atlas of human

anatomy

3.


1. Course title Introduction to human genetics

2. Code


4. Organizer of the study

programme(unit or institute,

faculty, department)



5. Level of studies (first, second and

third cycle)

First cycle

6. Academic year / semester first 7. Number of

credits

5

8. Lecturer/ Instructor Prof. Darko Bosnakovski


10. Course objectives(competencies):

Introduction to basic scientific knowledge of cell biology and genetics.

11. Course content:

1. Morphology and physiology of the cell.

2. DNA, iRNK, rRNK, tRNA,

3. Transcription, translation, replication of the DNA.

4. Inheritance of properties-principles, gene interaction; Genes- structure and function

genome, genotype, genetic code, alleles, and gene expression.

5. Structure and function of the chromosome. Mitosis and meiosis.

6. Autosomal, recessive inheritance, X linked inheritance, intermediate and

codominant inheritance.

7. Numerical chromosomal aberrations: aneuploidy, heteroploidy, monosomy,

nullisomy, trisomy.

8. Structural aberration: deletions, duplications, translocations, inversions.

9. Mutations. Mutagenic factors.

10. Autosomal and X-linked genetic diseases.

11. Genetic basis of malignancy (cancer).

12. Genetic engineering.

12. Course methodology:Lectures,exercises, seminar paper and practical activities

13. Total available time 5 ECTS х 30 hours =150

14. Distribution of available time 30+30+15+15+60


teaching,

e-teaching

30 hours


exercises,


work

30 hours






17.2. Seminar paper / project (presentation: written and/or

oral)

10 points









prerequisites

42 points acquired

20. Language of instruction Macedonian


instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Нада Митева

(Nada Miteva)

Општа Биологија

(цитологија, генетика,

ембриологија)

UKIM 2000

2. Мирјана Ќаева

Пејковска

(Marija Kaeva

Pejkovska)

Медицинска генетика

( medical genetics)

UGD 2008

3.

22.2.



1. Essentials of Genetics Klug, Cummings and

Spencer

Benjamin

Cummings

2012


1. Course title Histology and Embryology

2. Code








third cycle)

First cycle

6. Academic year / semester First semester 7. Number of

credits

6

8. Lecturer/ Instructor Assistant professor Nevenka Velickova PhD

9. Required prerequisite courses Enrolled first year of studies

10. Course objectives (competencies): Introducing the histological structure, structure and

function of all types of tissues, organs and organ systems in man.

11. Course content:


Epithelial tissues

Connective tissue

Muscle tissue

Nervous tissue

Gastrointestinal system

RES

Respiratory system. urogenital system

Nervous system. Endocrine system

Spermatogenesis and oogenesis

Embryonic development

Organogenesis

Placentation


Making permanent histological preparations

Epithelial tissues

Conective tissue

Muscle tissue

Nervous tissue

Gastrointestinal system

Glands in the gastrointestinal system

RES

Respiratory system. urogenital system

Nervous system. Endocrine system

Spermatogenesis and oogeneza

12. Course methodology: Lectures,exercises,seminar paper and practical activities

13. Total available time 6 ECTS + 30 hours = 180 hours



teaching,

e-teaching

30 hours


exercises,


work

45 hours







oral)

10 points









prerequisites

42 points acquired



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Луис Карлос

Жунквеира, Хосе

Карнеиро

Основи на

хистологијата

Табернакул 2010

2. Хистологија со

ембриологија

Нада Митева

3. Хистологија со Невена Костовска,

ембриологија Лилјана Миленкова

22.2.



1. Danica Roganivik -

Zafirova

Cytology


1. Course title Communication skills

2. Code








third cycle)

First cycle


credits

6

8. Lecturer/ Instructor Assistant professor Gordana Panova

9. Required prerequisite courses Enrolled in first year

10. Course objectives (competencies): Knowledge and understanding of basic

communication rules and the individual needs to communicate with other people

- Organizing an active and independent learning communication skills and preparing

students for effective learning basic communication skills

- Training for establishing effective communication between staff health workers,

patients and their relatives and friends, as well as the formation of feedback information

for successful communication, with special emphasis on health communication.

- Communication advantages, cooperation and teamwork with the University and in

health care facilities

11. Course content:

Communication (definition, verbal and nonverbal communication styles). Importance of

non-verbal communication, body language (posture, eye contact, pitch, and loudness,

adequate mimics, personal space ...). Ability to hear, barriers for good communication,

negotiation, communication between healthcare professionals (code of conduct,

speech, dress, etc.) Communication between patient- doctor, patient-nurse, health

worker (problematic reactions, adequate reactions), Tech Troubleshooting and

relaxation techniques, Burn Out (definition, cause, solution), aggressive communication

style, passive communication style.Communication between health workers in all

health institutions, outpatient clinics, hospitals, clinics, sanatoriums.

12. Course methodology:lecture, exercises, consultations

13. Total available time 6ECTS + 30 hours = 180 hours



teaching,

e-teaching

30 hours


exercises,


work

45 hours







oral)

10 points









prerequisites

Passed two colloquia, attendance and

presentiation of project assignment, and

acquired at least 42 points.



instruction

Self-evaluation

Written and oral presentation of the learning

content,practical examples from hospitals

22.

Literature

22.1.

Required literature


1. Doc.dr.G.Panova Communication skills UGD-Stip

2010

2. K.R.Seturman Communication skills in

clinical practice

Tabernakul

2010

3. Hilde and Tom Eide, Communication Udruzhenje

med.sesti

Belgrade

2006

22.2.



1. Marcia Lewis Carroll

Tamparo Medical

Law, Ethics and

Bioethics Academic

Press,

Tabernakul-

Skopje

2010

2. Marich John Medical

Communication skills

in clinical practice

Faculty of

Medicine,

Belgrade,

2005

3. R.C.Petterson

Based Learning

problems

Biokonto Igalo 2008

Annex

No.3

Course Programme - first, second and third cycle of study

1. Course title Clinical psychology

2. Code



programme (unit/ institute,

department)



5. Level of study (first, second, third

cycle)

First cycle

6. Academic year / semester First Academic

year

first semester

(1+1+1)

7. Number of

ECTS credits

2

8. Lecturer/ Instructor Prof. Lence MIloseva, Ph.D



-To become familiar with basic concepts and tasks of clinical psychology and health

psychology and their applicability in medical settings.

-To gain knowledge and understanding of the concepts, structure, psychological

processes and personality changes through different developmental periods.

- Introduction to basic principles of psychological approach, preparation and

implementation of psychological interventions with patients and/or inpatients;

knowledge and understanding of human behavior in medical settings, the person’s

reactions to illness.

-To become familiar with biopsychosocial model of health, psychological aspects of

somatic diseases, and some of the most common mental disorders; assessment of

different approaches to diagnosis and treatment and understanding of the link of these

different approaches to their potential impact on patients.

-To gain knowledge and methods for maintaining an promoting mental health and well

being .

-To develop communication skills (doctor/patient).

11. Course content:

General part

Introduction to Medical Psychology as a science (Clinical and Health

psychology in medical settings).Biopsychosocial model of health and

illness.

Human development. Child and adolescent psychology. Psychology of

adulthood and aging.

Psychology of patients (Psychological aspects of hospitalization. Child as a

patient. Adult as a patient. Geriatric patients. Psychological preparation for

medical examinations and surgery interventions; intensive care).

Psychology of pain (Psychological aspects of pain and methods of coping).

Communication in medical settings.

Special part

Stress and coping.

Mental health and mental disorders.

Psychoneuroimmunology, AIDS and cancer; Psycho-oncology;

Psychological aspects of chronic and terminal illness.

Psychosomatic illness; Psychological aspects of cardiovascular

disease; brain injury; Brain stroke; Psychological aspects in prevention

of somatic illness; Psychological aspects of pregnancy.

Death and dying.

Positive health psychology.

Health promotion. Family, health and illness.

12. Course methodology:

seminars, interactive method: group work, reports, homework, seminar papers,

discussion, debate, cooperative studying techniques, individual work, simulation of

extra-curricular educational activities, individual studying

13. Total amount of available time: 2ECTS х 30 hours = 60 hours

14. Distribution of available time: 15+15+15+5+10

15. Forms of teaching activities 15.1. Lectures- theoretical

classes

15 hours

15.2. Practice(laboratory,

theoretical) seminars, team

work

15 hours





17.1. Tests 70

17.2. Seminar paper/project (presentation: oral and written)

17.3. Attendance and participation

17.4. Oral exam

18. Grading system(points /grade) to 50 points 5 (F)

from 51 to 60 points 6 (E)

from 61 to 70points 7 (D)

from 71to 80 points 8 (C)

from 81to 90 points 9 (B)

from 91 to 100 points 10 (A)


prerequisites

60% success from all pre-exam activities or 42

points from the mid-term tests and the seminar

paper as well as attendance and participation in

class



instruction

Self-evaluation

22.

Literature:

22.1. Required literature

Ordinal Author Title Publisher Year

numbe

r

1. Милошева, Л. Клиничка психологија

– курс на е-учење,

УГД, Факултет за

медицински науки

УГД,

Факултет

за

медицинск

и науки

2013

2. Berger, J, & Mitic, M. Uvod u kliničku

psihologiju

Beograd:

Primenjena

psihologija

2002

3. Милошева, Л. Развојна психологија

Штип: УГД 2013

4. Havelka, M. Zdravstvena psihologija Jastrebarsk

o:Naklada

Slap

2002

22.2.


Ordinal

numbe

r

Author Title Publisher Year

1. Nietzel,M.T.,

Bernstein, D.A. &

Milich, R.

Uvod u kliničku

psihologiju

Jastrebarsko:

Naklada Slap

2002

2. Michie S. Abraham C. Health Psychology in

Practice

Oxford: BPS

Blackwell

Publishing

2004

3. Marks, D.F., Murray,

M., & Evans, B.

Health psychology:

Theory, research, and

practice

London:

SAGE

2011

Annex No.3 Course Programme- first cycle studies

1. Course title Foreign Language1 (English 1)

2. Code UGD100112



program(unit or institute, faculty,

department)




third cycle)

First cycle

6. Academic year / semester first semester 7. Number of credits 4

8. Lecturer/ Instructor Prof. Biljana Ivanovska, PhD Prof. Tole Belčev and

Senio Lecturer MA Snezhana Kirova

9. Required prerequisite courses Enrolled first year

10. Course objectives (competencies): The aim ofthe course is to enable students to supplement

and expand their language skills and to use them in specific situations, verbal

communications in medicine through the integrated use of linguistic feature sof discourse.

11. Course content:

Medical texts are organized according to the classification of human body systems.Practicing

pronunciation medical terms, translation of certain terms and phrases, lexical exercises for

presentation and evaluation of medical terminology,exercise sto prepare students to be

informed,selective and analytical reading through deductive and inductive conclusion, training

students for self-direction,writing a short dialogue, summaries, opinions or short articles on a

given topic.

12. Course methodology: seminars, interactive method: group work, lectures, homework, papers,

discussion, debate, cooperative learning techniques, Individual work, simulation of

extracurricular educational activities, independent learning.



15. Forms of teaching activities 15.1. lectures - theoretical teaching

15.2. Practice (laboratory,theoretical),

seminars, teamwork





17.1. Tests 70 points

17.2. Seminar paper/project (presentation: written and/or oral) 10 points


18. Grading system (points /grade)

up 50 points 5

19.

Signature and final exam

prerequisites

51 to60 points 6

61 to70 points 7

71 to 80 points 8

81 to90points 9

91 to100 points 10

60% of the success of the pre-

test activities, and 42 points

from two colloquia, seminar

paper, attendance at lectures

and exercises

20. Language of instruction English


instruction

Self-evaluation

2.

Literature

22.1.

Required literature


1. Pandora Dimovska Englishfor

medicalanddental

UKIM 2000,

Skopje


1. Course title Foreign Language1 (Italian language 1)

2. Code UGD100212








third cycle)

First cycle

6. Academic year / semester first semester 7. Number of

credits

4

8. Lecturer/ Instructor Assistant Professor Biljana Ivanovska

Professor Tole Belcev

Senior Lecturer Snezana Kirova



Students are to get acquainted with the basic notions of essential Italian vocabulary

used in situation from the everyday life; develop ability to ask and to give information,

to greet, to introduce themselves, to describe the environment where they live and act,

to describe a person’s physical appearance, to speak about their habits and interests,

to communicate on the telephone, to order in a restaurant, to narrate events in the past

etc. Introduction to basic vocabulary, reading, listening, speaking and writing skills

practice. Acquisition of reading and writing skills and basic grammatical word classes:

definite and indefinite article, gender and number of the nouns and adjectives,

descriptive, possessive, demonstrative, interrogative; subject pronouns, numerals,

present tense, prepositions, adverbs of place, etc.

11. Course content:

1. The alphabet, pronunciation, noun, personal information, greetings and farewells

2. Adjectives, personal pronouns, nationality

3. Definite articles

4. The verbs "to have" and "to be”

5. Present simple tense: regular verbs; formal, polite form

6. Writing letters, talking on the phone, requesting and providing information

7. Describing physical appearance, regions and cities in Italy

8. Present simple tense: irregular verbs

9. Leisure activities; describing the environment

10. Modal verbs, numbers, days of the week, telling time

11. Uses of the prepositions, expressing uncertainty, gratitude, indicating possession

12. Uses of the adverbs of place; possessive adjectives

12. Course methodology:Interactive exercises, group work, essays, homework, seminar

paper, discussion, debate, lectures, techniques of cooperative learning, individual

exercises, simulation of extracurricular educational activities, self-directed learning, use

of e-learning in lectures and practical exercises.




teaching,

e-teaching


exercises,


work







oral)

10 points









prerequisites




class

20. Language of instruction Macedonian and Italian language


instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. MARIN,T. &

MAGNELLI,S

Progetto italiano

1(Libro dello studente)

Edilingua

2. MARIN,T. &

MAGNELLI,S

Progetto italiano 1

(Quaderno degli

esercizi)

Edilingua

3.

22.2.



1.

2.

3.

Annex

No.3

Course Programme - first cycle of studies

1. Course title Foreign language 1 (German language 1)

2. Code UGD100312


4. Organizer of the study programme

(unit/ institute, department)



5. Level of studies (first, second,

third cycle)

First cycle

6. Academic year / semester First semester 7. Number of

ECTS credits

6

8. Lecturer/ Instructor Biljana Ivanovska PhD, Marica Tasevska


10. Course objectives (competences): Development of the written and spoken competence

and acquiring the modern and current events in the German-speaking countries.

11. Course content:

Basic German vocabulary, reading, listening, speaking and writing.


Seminars, interactive method: group work, papers, homework, seminar paper,

discussion, debate, techniques of cooperative learning, Individual work, simulation of

extracurricular educational activities, independent learning.

13. Total amount of available time: 4 ECTS х 30 hours = 120 hours



classes


theoretical) seminars,

team work





17.1. Tests 60

17.2. Seminar paper/project (presentation: oral and written) 10

17.3. Attendance and participation

17.4. Oral exam 30

18. Grading system(points /grade) to 50 points 5 (five) (F)

from 51 to 60 points 6 (six) (E)

from 61 to 70points 7 (seven) (D)

from 71to 80 points 8 (eight) (C)

from 81to 90 points 9 (nine) (B)

from 91 to 100 points 10 (ten) (A)


prerequisites




class

20. Language of instruction German language, Macedonian language


instruction

Self-evaluation

22.

Literature:

22.1.

Required literature

Ordinal

numbe

r


1. Susanne Kalender

Petra Klimazyk

Schritte international

1Deutsch als

Fremdsprache/

Hueber

Verlag

2006

2. Dr. Dimitrija Gacov Deutsche Grammatik National

University

Library

“NUB

Kliment

Ohridski”

Skopje

1995

3. Ranka Grceva

Peter Rau

Grosses Makedonisch-

Deutsch, Deutsch-

Makedonisches

Woererbuch

Magor Skopje

2006

22.2.


Ordinal

numbe

r


1. DUDEN Grammatik der

deutschen Sprache

Mannheim/Wi

en/Zürich:

Dudenverlag

(=Der Duden

in 12 Bänden

Bd. 4).

1995

2. Monika Reimann Grundstufen-

Grammatik für Deutsch

als Fremdsprache

Max Hueber

Verlag 2001

Leipzig

1979

Annex

No.3

Course Programme – first cycle studies-

1. Course title Foreign language 1 (French language 1)

2. Course code UGD100412


4. Organizer of the study programme

(unit/ institute, department)



5. Level of studies (first, second, third

cycle)

First cycle

6. Academic year / semester First year / first

semester

7. Number of

ECTS credits

4

8. Lecturer/Instructor Tole Belchev, Biljana Ivanovska, Snezana Kirova

9. Required prerequisite courses Basic knowledge of French acquired in previous

education

10. Course objectives (competences):

Acquisition of skills for oral and written comprehension and expression in given

situations. Capability for correct formulation of simple statements; Capability for

communication in everyday situations; Knowledge of the most important milestones of

the French civilization.

11. Course contents:

Grammar: Mastering the basic rules of pronunciation (dropping vowels, phonetic

bonding, and adding consonants.) Verb groups and their variations in the formation of

the Present Tense. Common and proper nouns, gender and number of nouns. Definite

and indefinite article, partitive article, article omission, connecting pronouns with

propositions. Personal pronouns, use of long pronominal forms, bonding pronouns with

propositions. Gender and number of adjectives, their place in relation to the noun.

Descriptive, demonstrative, possessive, interrogative, exclamative adjectives. Cardinal

and ordinal numbers. Imperative and conditional forms. Formation of negation. Types of

interrogative sentences.

Vocabulary: Description of personalities, professions, hobbies, food, housing ...

Culture and Civilization of France: regions, holidays, cultural landmarks.

12. Course Methodology:

Seminars, interactive methods: group work, lectures, homework, papers, discussions,

debates, cooperative learning techniques, Individual work, simulation for extracurricular

educational activities, independent study.

13. Total amount of available time: 4 ECTS х 30 hours = 120 hours



classes


theoretical) seminars,

team work





17.1. Mid-term tests 40

17.2. Seminar paper/project (presentation: oral and written) 10

17.3. Attendance and participation 20

17.4. Oral exam 30

18. Grading system (points /grade) to 50 points 5

from 51 to 60 points 6

from 61 to 70points 7

from 71to 80 points 8

from 81to 90 points 9

from 91 to 100 points 10


prerequisites

Cumulative score of 60% of all required activities

(midterm tests, attendance and seminar papers)

20. Language of instruction French and Macedonian

21. Course evaluation Self-evaluation

Annex No.3

22.

Literature:

22.1.

Required literature


1. Guy Capelle, Robert

Menand

Taxi! 1 Méthode de

français

Hachette 2002

2. Guy Capelle, Robert

Menand

Taxi! 1 Méthode de

français. Cahier

d'exercices

Hachette 2002

22.2.



1. АТАНАСОВ,

ПОПОСКИ,

КАЛАЈЛИЕВСКА)

Француско -

македонски речник

Просветно

дело

1992

2. ПОПОСКИ,

АТАНАСОВ

Македонско -

француски речник

Просветно

дело

1992

Course Programme- first cycle studies

1. Course title Foreign language 1 (Spanish Language 1)

2. Code



programme (unit or

institute, faculty,

department)


University Goce Delcev

5. Level of studies (first,

second and third cycle)

First cycle

6. Academic year / semester first semester 7. Number of credits 4

8. Lecturer/ Instructor Prof. Dusko Aleksovski

Prof. Biljana Ivanovska

Prof. Tole Belčev

Senior Lecturer MA Snezana Kirova

9. Required prerequisite

courses

none


Ability for oral and written expression and comprehension of simple situations of everyday

life, the ability to transfer content to read simple language and style, the ability of students to

give and seek information, to greet, to communicate by telephone, to discuss the topics of

everyday life, to describe the environment in which they live, to talk about their habits and

interests as well as determining the grammatical structures and contents etc..

11. Course content:

The basic features of the language. Rules for reading and writing. Master the basic

grammatical content: definite and indefinite article, gender and number of nouns, descriptive

adjectives, pointing, possessive, primes. Presentand past tense. Types of sentences. Short

dialogues from everyday life, seasons, writing short and simple compositions containing

studied grammatical structures and terminology.


Seminars, interactive method: group work, lectures, homework, papers, discussion, debate,

cooperative learning techniques, Individual work, simulation for extracurricular educational

activities, independent learning.



15. Forms of teaching

activities

15.1. lectures - theoretical teaching

15.2. Practice(laboratory,theoretical),

seminars, teamwork




17. Assessment method:

Interactive method, group work, lectures, homework, papers, discussion, debate, cooperative

learning techniques, Individual work, simulation extracurricular educational activities, self-

study, etc..


17.2. Seminar paper/project ( presentation: written and/or oral) 10 points


18. Grading system (points

/grade)

up 50 points 5 (five) (F)







prerequisites

60% success from pre- exam activities i.e. 42 points from two

colloquia, seminar paper, attendance at lectures and tutorials

20. Language of instruction Spanish and Macedonian languages

21. Method of monitoring the

quality of instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Ramon Sarmiento “Gramatica progresiva

de español para

extranjeros”

”Colibri”,

Софија

1998

2. A. Jarvis, R. Lebredo, F.

Mena-Ayllón

“Basic Spanish

Grammar”

Houghton

Mifflin

2000

Company -

USA

3.

22.2.



1. A. Gonzales Hermoso,

J. R. Cuenot, M.

Sanchez Alfaro

“Gramatica de español

lengua extranjera”

Madrid.

Spanija

1999

2. Cristina Karpacheva “Manual de español” Sofija 1998

Annex No.3 Course Programme- first/second/third cyclestudies

1. Course title Foreign language 1 (Russian language 1)

2. Code UGD100612







5. Level of studies (first, second

and third cycle)

First cycle


credits

4

8. Lecturer/ Instructor Snezana Kirova, Tole Belcev, Biljana Ivanovska


10. Course objectives (competencies): Ability associated with oral and

written expression and comprehension of simple, everyday situations. The student will

be able to make introductions, to give basic information about him/herself or other

persons, to describe basic activities and to take part in basic everyday dialogues, to

narrate stories, to give and seek information, to greet, to communicate by telephone, to

discuss topics of everyday life, to describe the environment in which they live, to talk

about their habits and interests as well as to learn the grammatical structures and

contents etc..

11. Course content: Basic language features. Reading, writing, spelling rules. Learning the

basic grammatical terms: definite and indefinite articles, gender and number,

descriptive adjectives, demonstrative, possessive adjectives, cardinal numbers.

Present tense and past tense. Accusative case.Types of interrogative and negative

sentences, seasons of the year. Short everyday dialogues and compositions, using the

grammatical structures and terminology they are familiar with.

12. Course methodology: Seminars, interactive methods: group work, essays, homework,

papers, discussions, debate, cooperative learning techniques, individual work,

extracurricular activities, simulations,self-study.



15. Forms of teaching activities 15.1. lectures / theoretical teaching,

e-teaching


exercises,

e-exams, seminars, team work








18. Grading system (points /grade) up 50points 5(five) (F)

51 to 60 points 6(six) (E)






prerequisites

60 % success from the pre-exam activity and the

seminar paper.

20. Language of instruction Macedonian language/ Russian language

21. Method of monitoring the quality

of instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Kathryn Szczepanska Russian – a self-

teaching guide

Wiley 2005

22.2.



2. Kathryn Szczepanska Russian – a self-

teaching guide

Wiley 2005


1. Course title Sports and recreation

2. Code UGD102712



programme(unit or institute, faculty,

department)




third cycle)

First cycle


credits

0

8. Lecturer/ Instructor Associate Prof. Biljana Popeska, PhD



Fulfillment of students’ needs for movement and physical activity. Maintenance and development

of students’ motor abilities.

11. Course content:

1.Basic physical preparation (introduction to fundaments and basic principles of physical activity,

exercise for strengthening of certain muscle groups)

2. Basic physical preparation (introduction to and application of different forms of warming,

exercises for strengthening of certain muscle groups)

3. Aerobics, martial arts and artistic gymnastics (according to the structure of the group)

4. Outdoor activities - hiking and orientation

5. Basketball (practicing basic basketball elements - travelling, passing, dribbling, double

dribbling)

6. Basketball (play)

7. Table tennis and badminton

8. Table tennis and badminton

9. Volleyball (play)

10. Handball (play)

11. Aerobics, martial arts, elementary games (according to the group structure)

12. Testing motor abilities, elementary games, modern and traditional dances

12. Course methodology:method of practical exercise, method of sport training

13. Total available time 12 hours

14. Distribution of available time 0+0+2/ per week


teaching,

e-teaching

0 hours


exercises,

e-exams, seminars,

team work

12 hours




17. Assessment method /

17.1. Tests / oral exams 0

17.2. Seminar paper / project (presentation: written

and/or oral)

0

17.3. Attendance and participation 0








prerequisites

60% presence on the practical activities



instruction

Motor tests, observation, self-evaluation

22.

Literature

22.1.

Required literature


1. Kukolj.M Antropomotorika Faculty of

sport and

physical

education,

Belgrade

2006

2. Wilmore, J. & Costill,

D.

Physiology of sport and

exercise, (Third

edition),

Champaign:

Human Kinetic,

Illinois.

2002

3. Мalacko,J. Bases of sports training

(Osnove sportskog

treninga)

Sports

academy,

Belgrade

2000

22.2.



1. Haywood, K., &

Getchell, N.

Life span motor

development

Champaign:

IL. Human

Kinetics.

2004

2. Magill, R. & Rouge.B Motor Learning Broun

Publishers,

Louisiana

1989

3. Malina, R.,

Bouchard, C. & Bar –

Or, O

. Growth, Maturation

and Physical Activity

(Second Edition).

Champaign:

IL. Human

Kinetics.

Malina,

R.,

BoucharD


1. Course title Physiology

2. Code




department)




third cycle)

First cycle

6. Academic year / semester Second

semester

7. Number of

credits

4

8. Lecturer/ Instructor Assistant professor Darko Bosnakovski PhD

9. Required prerequisite courses Enrolled first year of studies

10. Course objectives (competencies): Introduction to the normal functioning of the human

body and the basic mechanisms of normal functioning of individual organ systems.

During the practical training the students test their theoretical knowledge with the

performance of exercises and experiments in the laboratory and at the same time they

can see some reactions and mechanisms in vitro conditions.

11. Course content:


1. Introduction to Physiology - functional organization and general body cell

organization

2. Bodily fluids and electrolytes, blood

3. Cardiovascular system

4. Nervous system

5. Muscle system

6. Respiratory system

7. Digestive system

8. Urinary system

9. Reproductive system

10. Endocrine system

11. Thermoregulation and metabolism

12.Sensory system


1. Basic elements and function of blood and blood plasma

2. Neuro-muscular system, mionerval link

3. Endocrine glands

4. Heart and the heartbeat, factors that affect heart rate and its registration

5. Breathing system and vital capacity

6. Resorption of nutrients and giving injections

7. Saliva, gastric juice, bile

8. Urinary system

9. Reproductive system - female

10. Reproductive system - male

11. Supply of materials and energy and determination of calorific value of nutrients

12. Thermometers, thermoregulation and getting hypothermia



Interactive teaching: lectures in large groups, discussions and engaging students.

Multimedia teaching.

E-learning.

Continuous on-line contact with students.

Individual consultations with students and consultation groups.


Practical laboratory exercises in small groups.

Auditorial exercises.

Final exercise.

13. Total available time 4 ECTS х 30 hours =120 hours



teaching,

e-teaching

30 hours


exercises,


work

15 hours







oral)

10 points









prerequisites

42 points acquired



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Gayton C.A..

Физиологија човјека и

механизми болести.

Медицинска

наклада,

Загреб.

1995

2.

Трајковски В.

Физиологија со

функционална

анатомија

Филозофски

факултет,

Институт за

дефектологи

ја, Скопје.

2007

3. Ицко Ѓоргоски, Митко

И. Младенов

Физиолошки

практикум

ПМФ-Скопје 2006

22.2. Supplementary literature


1. Практикум по

физиологија со

функционална

анатомија

Трајковски В, Рашиќ

О.

Филозофски

факултет,

Институт за

дефектологи

ја, Скопје.

2008

2. Physiology Linda Costanzo Saunders 2006

3. Human Physiology: The

Mechanisms of Body

Function - 8th Edition

Arthur Vander and

James Sherman and

Dorothy Luciano

McGraw-Hill

Education

2006


1. Course title Biochemistry

2. Code



programme(unit or

institute, faculty,

department)





First cycle

6. Academic year / semester Second semester 7. Number of credits 4

8. Lecturer/ Instructor Assistant Professor Tatjana Ruskovska, PhD


courses


Acquiring theoretical and practical knowledge about life functions through learning about the

structure, biochemical functions and metabolism of biomolecules, regulation of biosynthesis

and degradation, and integration of metabolism.

11. Course content:

- Water and electrolytes

- Proteins – classification, structure, function and metabolism

- Lipids – classification, structure, function and metabolism

- Carbohydrates – classification, structure, function and metabolism

- Enzymes and coenzymes – structure and mechanism of reactions

- Nucleic acids – structure and biosynthesis of proteins

- Conservation of energy and integration of metabolism


Teaching, laboratory experiments, work in groups and individual work.

13. Total available time 4 EKTS x 30 hours =120 hours

14. Distribution of available time 30+15+15+15+45=120


activities

15.1. Lectures - theoretical teaching

30 hours

15.2. Practice(laboratory, theoretical),

seminars, teamwork

15 hours




17. Assessment method:

Interactive method, group work, lectures, homework, papers, discussion, debate, cooperative

learning techniques, Individual work, simulation for extracurricular educational activities, self-

study, etc.





/grade)








prerequisites




Self-evaluation

22.

Literature

22.1.

Required literature


1. Карлсон Биохемија и

патобиохемија

Нид

“Микена”-

Битола

2012

2. Лениџер Принципи на

биохемија

Нид

“Микена”-

Битола

2012

3. Кетрин Декистон,

Џозев Топинг, Роберт

Корект

Општа, органска и

биохемија




1. Џекова С. и сор. Биохемија Нип “Форум”

Скопје

2005

2. Т. Рушковска Основи на биохемија УГД 1993


1. Course title Microbiology and Parasitology

2. Code








third cycle)

First cycle

6. Academic year / semester 2013-2014 /II 7. Number of

credits

6

8. Lecturer/ Instructor Ass. prof. d-r Vaso Taleski, MD, D-r Sc.

Ass. d-r Marina Danilova



Basic aim of the course program is to introduce and enable students to acquire

theoretical, practical knowledge, skills and competences in field of microbiology



1. Introduction of history and development of microbiology science,

significance of microorganisms. Classification of bacteria, taxonomic

categories, nomenclature, size, shape and disposition of bacteria

2. Morphology and structure of bacterial cells: capsule, cell wall, cytoplasmic

membrane, cytoplasm and cytoplasmic inclusions, fimbrae and pili,

flagellum, bacterial spores, bacterial movement. Conditions for growth and

multiplication, growth phases, bacterial colonies

3. Chemical composition of bacteria, metabolism, mechanism of bacterial

feeding, metabolism of energy

4. Metabolism of nucleic acids. DNA replication. Nucleic acids decomposition

Bacterial genetics. Bacterial phenotype and genotype variations. Gene

transfer

5. Spreading of microorganisms. Associations of microorganisms.

Pathogenicity and virulence. Infections and infective diseases. Nonspecific

and specific immunity in humans. Immunotherapy and immune-prophylaxis.

6. Sterilization and disinfection. Antibiotics and chemiotherapeutics.

Microorganism’s resistance toward antibiotics. Side effects of

chemiotherapeutics.

7. Aerobic and anaerobic Gram positive and negative cocci.

8. Gram negative rods. Gram positive rods: sopreforming and non-

sporeforming

9. Spiral bacteria. Rickettsia. Mycobacteria. Actinomyces,Nocardia

10. Morphology, structure, classification and multiplication of viruses.

Importance of viral infections

11. Most important DNA and RNA viruses

12. Morphology, structure, classification and multiplication of fungi. Morphology,

structure, classification and importance of parasites


1. Principles of safety work in microbiology laboratory. Sampling, packaging and

delivering samples for microbiological testing

2. Microscope and microscopic examinations of microorganisms (light

microscope, fluorescence microscope, electron microscope). Staining of

microorganisms (Gram, Giemsa, Ziehl-Neelsen)

3. Culture media and bacterial cultivation. Identification of bacteria (classical

biochemical reactions, automatic systems for identification)

4. Antibiotic susceptibility testing of bacteria/antibiogram (classical diffusion and

dilution methods, automatic systems, E-test). Hemocultures

5. Microbiological diagnosis of wound infections and respiratory infections

6. Microbiological diagnosis of genital-urinary and sexually transmitted infections

7. Microbiological diagnosis of enteropathogens

8. Classical serologic reactions. Rapid tests

9. Immune-enzymes methods (ELISA, VIDAS)

10. Sterilization and Disinfection

11. Methods of viral diagnosis. Hepatitis markers. Diagnosis of HIV infections.

12. Diagnosis of yeasts and parasites

12. Course methodology: Methods of oral and visual learning/presentations and practical

work in the lab.




teaching, e-teaching 30 hours


exercises,


work

45 hours







oral)

10 points

17.3. Attendance and participation during lecturing 10 points

17.4 Attendance and participation during lab practical work 10 points

17.5 Final exam 30 points








prerequisites

Requirements for signature: presence at

lectures and practical work.

Requirements for final exam: at least 42 points

from two colloquia, presence at lectures,

practical lab work and seminars (paper/project -

presentation. Colloquia are not conditionally

connected. For students with points over 37 and

less than 42, professor could organize

additional colloquium with maximum of 10

additional points



instruction

Student evaluation

Self-evaluation

22.

Literature

22.1.

Required literature


1. Greenwood D. et all. Medical microbiology Project of the

Government

of the

Republic of

Macedonia,

for translation

of vocational

and scientific

books

17-

edition,

2006,

Translat

ed in

2011

2.

Panovski N. et all.

Guest / invited author:

Vaso Taleski

Medical microbiology

- General part

Institute of

Microbiology

and

parasitology,

Medical

faculty

Skopje.

2011

3.

Panovski N. et all.

Guest / invited author:

Vaso Taleski

Medical microbiology

- Special part

Institute of

Microbiology

and

parasitology,

Medical

faculty

Skopje.

2011

4. Jawetz, Melnick, &

Adelberg

“Medical Microbiology” The McGraw-

Hill

Companies

24th ed.,

2007

22.2.



1. Milena Petrovska et all. “Handbook on medical

microbiology and

parasitology”

Institute of

Microbiology

and

parasitology,

Medical

faculty

Skopje,

5th ed.

2010

2. Vaso Taleski “Microbiology” Authorized

presentations

2008


1. Course title Nursing care

2. Code








third cycle)

First cycle

6. Academic year / semester 2012/2013

second

7. Number of

credits

6

8. Lecturer/ Instructor Doc.dr.Gordana Panova

9. Required prerequisite courses Enrolled in second, third year

10. Course objectives (competencies): Teaching unit contributes primarily to the

development of the following general and specific competences: Understanding the

role of the nurse not only as the performance of duty but mandatory input of love and

compassion in working with patients on admission procedures sick, making of the

hospital bed and changing the bed cover, perform physical measurements, an

emergency procedure when applied knowledge of various types of diets with different

diseases, measuring temperature and differentiating temperature curves, measurement

of pulse and blood pressure, preparing the patient for diagnostic tests,catheterization,

giving parenteral and intravenous injection, knowledge of the sources of infection and

measures for personal protection, mode of treatment for anaphylactic shock, collapse

and coma, placement and care of the operated patients, nourishing terminally ill and

recognizing the signs of dying and determination of death.


Familiarization with the content and importance of the course Nursing care;

Organization of hospitals and hospital service;

Hospital room, hospital bed and hospital cover;

Admission of patients (new sick and emergency);

Nutrition of patients, cleanliness of the body of the patient and the patient's care for

mental mood;

Observation of the patient, vital signs, and the relationship between them;

Diagnostic testing on the patient;

Control of defecation, urination and care for vomiting;

Storage and delivery of drugs;

Entering injectable drugs in the body;

Prevention and protection against infection;

Medically - tehnical operations in which the nurse assist the physician;

Taking actions in case of anaphylactic shock, collapse, coma and acute respiratory

failure (ARI);

Care of surgical patients;

Care of the elderly, chronically ill and deathbed patients;

12. Course methodology:lecture, exercises, consultations




teaching,

e-teaching

30 hours


exercises,

45 hours


work







oral)

10 points









prerequisites

Passed two colloquia, attendance on lectures

and presentation of seminar paper, and scored

at least 42 points.



instruction

Self-evaluation: Immediate lectures (face to

face) with multimedia presentations, interactive

lessons, conducting practical classes equipped

with cabinets, work phantoms, divide students

into pairs called (role playing) and use of other

educational aids and teaching aids

Written and oral presentation of the learning

content,practical examples from hospitals

22.

Literature

22.1.

Required literature


1. Doc.dr.G.Panova Helth Care painful UGD-Stip

2010

2. Dr. Likar Dusan

General and special

care of the sick;

Prosvetno

delo-Skopje

2010

3. Barham P.. A.

Care of the ill and

medical equipment;

Tabernakul-

Skopje

2011

22.2.



1. Fuchkar G.

Process of health

care;

MedicalSchool

- Zagreb

2007

2. Krstic A.

New content sister

work;

Faculty of

Medicine,

Belgrade,

2005

3. Rozen, Berkin Preventive Health

Care

Tabernakul

Skopje

2011


1. Course title Ecology and hygiene

2. Code








third cycle)

First cycle

6. Academic year / semester

Second

semester

7. Number of

credits

2


9. Required prerequisite courses Enrolled second year of studies

10. Course objectives (competencies): The purpose of this subject is for

the students to gain basic knowledge from the area of medical ecology, the protection

of the environment and hygiene.

11. Course content:

Introduction to ecology

Air pollution

Water pollution

Waste materials

Chemical components in the environment

Climate and Microclimate

Radiation, Noise

Introduction to hygiene

Hygiene in public and communal facilities

Education facilities hygiene

Health facilities hygiene

Personal hygiene


Lectures,exercises,seminars and practical activities




teaching,

e-teaching

30 hours


exercises,


work

0 hours







oral)

10 points









prerequisites

42 points acquired



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Michail Kocubovski Hygiene whit medical

ecology

University of

Goce Delcev

- Stip

2011

2. R. Čosic Udzbenik Higiene 1983

3. Milto Mulev Protection of the

environment

1997

22.2.



1. Kocijancic Radojka Higiena Zavod za

udzbenike I

nastavna

sredstva,

Beograd

2002

Annex No.3


1. Course title Epidemiology

2. Code



program(unit or institute,

Faculty, department)





First cycle


8. Lecturer/ Instructor Prof. Dr. Gorgi Shumanov, PhD


courses

Verified first semester


Acquiring a basic knowledge of epidemiology and public health. Introduction to measures for

prevention and combat diseases and health deterioration. The student will gain knowledge of

the epidemiological characteristics of infectious (intestinal, respiratory, transmissible

infectious diseases, zoonoses and other diseases) and non-infectuous (cardiovascular

disease, cancer, diabetes, traumatism) diseases.

11. Course content:


1. Epidemic process

2. Epidemiological methods

3. Types of outbreaks.

4. Forms of epidemic process

5. The occurrence of infection and communicable diseases and ways of transmitting

infectious diseases.

6. Prevention of disease and ill-health.

7. Preventive medical care in military and emergency conditions.

8. Epidemiological features of intestinal infectious diseases.

9. Epidemiological characteristics of infectious respiratory diseases.

10. Epidemiological characteristics of infectious disease transmission.

11. Epidemiological features of zoonoses.

12. Epidemiological characteristics of non-communicable diseases and health damage.

Practical instruction:

1. Epidemiological methods and design studies

2. Methods of collecting information, epidemiological survey, sample

3. Epidemic process, forms the epidemic process, epidemiological models of disease

occurrence

4. Epidemiological characteristics and examples of alimentary, drip-aerogeni, contact and

transmissible epidemic

5. Immunization: compulsory vaccination and vaccination on epidemiological indications

6. Prevention of occupational exposure

7. Epidemiological features of intestinal infectious diseases

8. Epidemiological characteristics of infectious respiratory diseases

9. Epidemiological features of contact diseases

10. Epidemiological features of transmissible infectious diseases

11. Epidemiological features of chronic non-communicable diseases

12. Epidemiological features of malignant neoplasm, diabetes, addictions.

12. Course methodology:Lectures, exercises, methods of group discussions, individual

assignments, seminar papers, presentation of a scientific work


14. Distribution of available time 30+15+15


activities

15.1. lectures - theoretical teaching

30 hours

15.2. Practice(laboratory,theoretical),

seminars, teamwork

15 hours








18. Grading system (points /grade) up 50 points 5 (five) (F)







prerequisites

Attendance and scored at least 42 points from all pre-

exam activities.



of instruction

Self evaluation

22.

Literature

22.1.

Required literature


1. Gorgi Shumanov,

Blaze Nikolovski

Epidemiology and

Public Health

"Progress",

Tetovo

2009

2. Theodor H.Tulchinski

Elena A.Varavikova

New Public Health Student word

"Skopje

2003

3. Lence Mircevska,

Doncho Donev, Ilija

Gligorov

Health education Bitola 2006

22.2.



1. Blaze Nikolovski Epidemiology "Progress",

Tetovo

2003

Annex No. 3 Course Programme - first cycle studies

1. Course title Computer science

2. Code



programme(unit orinstitute, faculty,

department)



5. Level of studies (first, second, or third

study cycle)

First cycle


8. Lecturer/ Instructor Ass. Professor Zoran Zdravev, PhD


10

.

Course objectives(competencies):

Adopting the basic concepts of computer science and concepts for using computers for

communication, research and office work

11

.

Course content:

Introduction to computer science: algorithms, abstraction, history,

Computer hardware: introduction, types, architecture of computer systems, Murau law

Computer hardware: Peripherals, Computer Memory, digital identification;

Computer software: applicative software, open source software licenses;

Computer software: system software, programming languages;

Computer software: web services, online document storage and editing systems,

Computer networks: LAN, MAN, WAN, topologies, applications that run on network

components, connectivity;

Computer networks: Internet, intranet, extranet, Internet services;

Computer security: a concept, a security risk, malicious software, unauthorized access,

cryptography;

Information systems: introduction, types, ERP, CRM, HR, SCM;

Content Management Systems CMS: DMS, DAMS, WCM, ECP, ERS;

Databases: fundamentals, types, use

12

.

Course methodology: lectures, laboratory exercises, e-learning, individual and team projects,

consultations.

13

.

Total available time 4 ECTS х 30 h = 120 hours

14 Distribution of available time 30+15+15+10 +50 = 120 hours

.

15

.

Forms of teaching activities 15.1 lectures / theoretical

teaching, e-teaching

30 hours

15.2 theoretical and practical

exercises,


work

15 hours

16

.

Other forms of activities 16.1 Project work 15 hours

16.2 Individual work 10 hours

16.3 Homework 50 hours

17 Assessment method

17.1 Tests / oral exams 70 points

17.2 Seminar paper/project (presentation: written and/or oral) 10 points

17.3 Attendance and participation 20 points

18 Grading system (points /grade) Up 50 points 5 (five) (F)






19 Signature and final exam prerequisites 60% of term activities or minimum 42 points from 2

midterm exams, project activities and attendance

on lectures and discussions

20 Language of instruction Macedonian

21 Method of monitoring the quality of

instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Zoran Zdravev etc.. Informatics - script UGD 2012

2. Zoran Zdravev etc..

Practicum in Informatics

UGD 2012

Practicum in

Informatics

UGD 2012

3.

22.2.



1. Glenn Brookshear „Computer Science –

an overview“

Pearson

International

edition

2009

2. Carl Reynolds and Paul

Tymann

„Principles of Computer

Science“

McGraw Hill 2008

3. James O’Brien „Introduction to

Information Systems “

McGraw Hill 2008

Annex No.3


1. Course title Pathophysiology

2. Code






Faculty of Medical science


and third cycle)

First cycle

6. Academic year / semester Second year / third

semester

7. Number of

credits

6

8. Lecturer/ Instructor Prof. dr. Zoran Handziski

9. Required prerequisite courses /

10. Course objectives (competencies): Introducing the students with the general

malfunctions and pathophysiological processes of the organism.

11. Course content:


1. Disorders of the structure and function of macromolecules

2. Disorders of subcelular structures

3. Disorders of energy metabolism and the metabolism of essential nutrients

4. Disorders of the turnover ofspecific metabolic compounds

5. Disorders of the turnover of water and electrolytes.

6. Disorders of the acid-base balance

7. Biologically active endogenous compounds in the pathophysiological processes

8. Disorders of neuro-vegetative regulation. Pathophysiological basis of pain.

9. Disorders of thermoregulation. Imunopathophysiology

10. Inflammation. Overall response of the organism to the harmful effects.

11. Circulatory shock. Disturbance of consciousness.

12. Disorders of development and growth. Malignant transformation and growth.


1. Pathophysiological basis of inheritance of diseases and syndromes

2. Cell death

3. Substrate hipoenergosis-starvation

4. Disorders of protein metabolism

5. Disorders of purine metabolism-Gout

6. Disorders of calcium, phosphate and magnesium turnover

7. Gastrointestinal hormones and neuropeptides

8. Reactions of tissue transplantation

9. Pathophysiology of aging

12. Course methodology: interactive teaching of lectures and tutorials, practical exercises.




e-teaching

30 hours


exercises,


45 hours















prerequisites

The Assessment method is based on the

accumulation of points scored: lectures,

tutorials, colloquia and seminar paper;

• colloquia are independent of each other,

i.e. passing one is not a prerequisite for

taking other colloquium;

• The final exam also does not depend on

colloquiums, they are not a requirement for

passing the final exam, but the total

number of points scored, which should not

be less than 42 points;

• In case of insufficient number of points for

passing the final exam, the professor can

arrange additional colloquium or additional

activity when it has a sufficient number of

candidates.



of instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Gamulin S et al. Pathophysiology 6th edition ,

Zagreb

2005

2. Vaskova O et al. Practicum in general

and special

pathological physiology

Skopje

3. Tadzer I et all. General pathological

physiology

Belgrade

22.2.



Annex No.3


1. Course title Pathology

2. Code




department)



Department of Pathology


third cycle)

First cycle

6. Academic year / semester second year /

third semester

7. Number of

credits

6

8. Lecturer/ Instructor Prof. Gordana Petrushevska, MD, PhD


10. Course objectives (competencies): Acquiring knowledge about etiology, mechanisms

and morphological changes in cells and tissues of the human organism under the

influence of pathological agents and diagnosis of those changes.

11. Course content:

1. Cell injuries, Cell Death, and Adaptations;

2. Acute and Chronic Inflammation;

3. Tissue Repair: Regeneration, Healing, and Fibrosis;

4. Hemodynamic Disorders, Thrombosis, and Shock;

5. Diseases of the Immune System;

6. Neoplasia;

7. Genetic and Pediatric Diseases;

8. Environmental and Nutritional Diseases;

9. General Pathology of Infectious Diseases;

10. Pathology of the Blood Vessels;


theoretical lectures, practical exercises, term papers, individual presentation




teaching,

e-teaching

30 h


exercises,


work

45 h






17.2. Seminar paper/project (presentation: written and/or

oral)

10 points


18. Grading system (points /grade) up 50 points 5 (five) (F)







prerequisites

The total number of pre-exam points scored

should not be less than 42 points.



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Kumar, Abbas,

Fausto, Mitchell

Robbins Basis of

Pathology, 8th

Saunders,

Elsevier

2010

2. Eduard K. Klatt Robbins and

Cotran Atlas of

Pathology

Saunders,

Elsevier

2009

3. Authorized

Lectures

22.2.



Annex No.3

Course Programme- First cycle studies

1. Course title Pharmacology

2. Code






Faculty of Medical science


third cycle)

First cycle

6. Academic year / semester Second/ Third 7. Number of

credits

4

8. Lecturer/ Instructor Ass. Professor dr. Trajan Balkanov



To introduce students with basic pharmacokinetic (absorption, distribution, metabolism

and elimination of drugs) and pharmacodinamic processes in the human organism, the

mechanism of action of drugs, factors that determine safety and efficacy, dosing and

factors affecting dosing of drugs , interactions and side effects of medications, and to

provide a review of the most basic characteristics of most drugs that are now used in

everyday practice

11. Course content:

1. Basic pharmacology, Pharmacodinamic (the effect of the drugs on the human

organism)

2. The mechanism of action of the drugs; Character of action, specificity and selectivity

3. Types of therapy, etiology, symptomatic; Quantitative aspects of the effects of drugs

4. Correlation among structure of the drug and pharmacological response; strength and

effectiveness of the drugs

5. The notion of accumulation and tolerance; mutual effect between the drugs; Side

effects on drugs (toxicity, allergic, genetically determined). Drug addiction

6. Drugs that act through the peripheral nervous system,

7. Pharmacology of the drugs that act through the central nervous system,

8. Treatment of cardiovascular disease, Haemostasis and Thrombosis, drugs that are

used in the treatment of anemia,

9. Treatment of respiratory diseases,

10. Treatment of diseases of the digestive tract,

11. The use of vitamins and hormones in daily therapy practice

12. Anti-infective drugs

12. Course methodology:Research, working in small groups, homework, practical work,

independent seminar paper, discussion, debate, individual work




teaching,

e-teaching

30 hours


exercises,


work

15 hours


16.2. Individual work 10 hour





oral)

10 points









prerequisites

Total number of pre-exam points scored should

not be less than 42 points.



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Ass.prof.dr. Trajan

Balkanov

Prof.dr. Srdjan Pesic

Pharmacology of

dentists – general part

authorized

lectures,

script

2013

2. Ass.prof.dr. Trajan

Balkanov

Pharmacology of

dentists – special part

authorized

lectures,

2013

Prof.dr. Srdjan Pesic script

3.

22.2.




1. Course title Introduction to internal medicine

2. Code





University Goce Delcev, Stip



and third cycle)

First cycle


semester

7. Number of

credits

6

8. Lecturer/ Instructor Prof. d-r Nikola Kamcev

9. Required prerequisite courses none


- to achieve basic knowledge in the basic internal diseases in order to learn the main

principles of health care of these patients

-to be able to practically implement the theoretical knowledge of internal diseases

11. Course content:

Diseases and conditions of the cardiovascular system

Respiratory diseases

Nephrology diseases

Rheumatology diseases and conditions

12. Course methodology:interactive lectures, practical classes, project work



15. Forms of teaching activities /

per week

15.1. Lectures / theoretical -

interactive teaching

45 hours

15.2. Practical exercises,

e-learning, seminar paper

30 hours





17.1. Attendance to the lectures and active participation maximum 10 points

17.2. Attendance to the practical lessons and active

participation

maximum 10 points

17.3 Continuous knowledge checking through exams maximum 2x20

points

17.4. Seminar paper/project (presentation: written and/or oral)

optional

maximum 10 points

17.5. Practical exam maximum 10 points

17.6 Final exam maximum 30 points








prerequisites

Cumulative score of 60% of all required activities

(midterm tests, attendance and seminar papers)



of instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Vladimir Serafimovski

and colleagues

Internal medicine Makedonska

riznica,

Kumanovo

2003

2. Faucu D.L, Kasper D.L.

LondoD.L. Braunwald E,

HauserS.L. JamesonJ.L.

LascalroJ.

Harrison’s principles of

internal Medicine

(Atlas), 17 -th edition

“Tabenakul”

Skopje

2013

22.2.



1. Charles D, Forbs,

William F, Jackson.

Clinical Medicine “Magor”

Skopje

2010

2. Ljubica Georgievska

Ismail, Lidija Poposka,

Ivan Trajkov, Nikola

Gjorgov

Electrocardiography Skopje:

(COBISS.

MK-ID

71834122)

2008

Annex No.3


1. Course title Immunology

2. Code








and third cycle)

First cycle


semester

7. Number of

credits

3

8. Lecturer/ Instructor Prof. d-r Darko Bosnjakovski


10. Course objectives (competencies): Through theoretical instruction students will learn

basic concepts and components of the immune system and how they function.

Through practical instruction students will be introduced to the basic methods of

examination which immunology uses.

11. Course content:

Theoretical instruction:

1.Introduction in Immunology

2. Immune system cells and organs

3. Innate immune responses

4. Complement

5. Acquired immune responses

6. B cells

7. Antibodies

8 T cell

9. Immunological mediators

10. Tolerance

11. Autoimmunity

12. Basic concepts in clinical immunology

Practical instruction:

1. Introduction to immunology and the general of the immune system.

2. Cells of the immune system and isolation

3.Recognition molecules for the cells of the immune system

4. Lymphoid organs and tissues, recognizing of their structural components

5. Enzyme immunoassay (ELISA), Enzyme-immunological test to detect HIV

6. Immunoelectrophoresis, Zone immunoelectrophoresis, Immunofixation

electrophoresis. Applying immunoelectrophoresis.

7. Immunochemical and immuno-physical-chemical methods.Chromatography

column.Ion exchange chromatography.Gelfiltration.Affinity chromatography.

8. Methods for obtaining monoclonal antibodies.

9. Northern and Western blot.

10. Immunocytochemistry and immunofluorescent staining, Principles of

flowcytometry.

11. Intracellular cytokine staining, ELISPOT

12. PCR - polymerase chain reaction, in situ hybridization.


Lectures, group discussions methods, theoretival and laboratory exercises, individual

assignments, seminar paper, presentation of paper.




e-teaching

15 h


exercises,


15 h














19. Signature and final exam At least 42 points acquired.

prerequisites



of instruction

Self-evaluation

22.

Literature

22.1.

Required literature

no. Author Name Publisher Year

1. Kubi Imunology, 6th edition Tabernakul

2011

2. Darko Bosnjakovski

authorozed lectures

Basics in immunology

3. Spiroski M, Trajkov D, et

al

Imunoloski praktikum IIBHG<

Medical

faculty,

Skopje

2006

22.2.


no Author Name Publisher Year

1. Ivan Roitt et al. Immunology, 4th

edition

Mosby 1996

2. Helen Chapel et al Basics in clinical

immunology

Tabernakul 2010

Annex No.3


1. Course title Cell biochemistry

2. Code





Goce Delcev University



third cycle)

First cycle

6. Academic year / semester Second year /

Third semester

7. Number of

credits

5

8. Lecturer/ Instructor Prof. Tatjana Ruskovska



Learning about metabolic processes in the cell and in the whole organism, and their

regulation. Getting a basic knowledge about the research in cell biochemistry.

Course content:


1. Definition of the metabolism. Anabolic and catabolic processes in the organism

of the healthy people.

2. Cofactors and high-energy compounds.

3. Metabolism of carbohydrates, first part. Glycolysis.

4. Metabolic transformation of the pyruvate. The cycle of three carboxylic acids.

5. Respiratory chain and oxidative phosphorylation. Energetic contribution of the

metabolism of carbohydrates,

6. Metabolism of carbohydrates, second part. Glycogenolysis, glycogenesis,

pentose-phosphate cycle, gluconeogenesis.

7. Metabolism of the lipids. Catabolism of the 3-acylglycerols. Β-oxidation of fatty

acids and energetic contribution. Ketogenesis. Biosynthesis of fatty acids,

phospholipids and sterols. Prostaglandins.

8. Metabolism of the lipoproteins in the blood plasma.

9. Metabolism of the proteins.

10. Metabolism of the amino acids.

11. Metabolism of the porphyrins. Metabolism of the nucleotides.

12. Photosynthesis.


1. Biochemical research and its specificity.

2. Basic procedures and techniques in biochemical research.

3. Hydrodynamic methods in cellular biochemistry.

4. Application of the techniques of electrophoresis in the biochemical researches,

first part.

5. Application of the techniques of electrophoresis in the biochemical researches,

second part.

6. Application of the chromatography in analysis of the cell material.

7. Laboratory methods for investigation of mitochondrial respiration.

8. Glycolysis.

9. Pentose-phosphate cycle.

10. Metabolism of the lipids.

11. Photosynthesis.

12. Final experiment.



Interactive teaching: Lectures in large group, discussion and involvement of the

students.

Multimedia teaching.

E-teaching.

Consultation in groups and individually.


Laboratory experiments in small groups.

Theoretical discussion about some experiments.

Final experiment.




teaching,

e-teaching

30


exercises,


work

30

16. Other forms of activities 16.1. Project work 15 Hours

16.2. Individual work 15 Hours

16.3. Homework 60 Hours




oral)

10 points









prerequisites

Acquired at least 42 points



instruction

Self-evaluation

22.

Literature

22.1.

Required literature

No. Аuthor Name Publisher Year

1. S. Dzekova et al BIOHEMIJA Skopje 2006

2. B. Gorgeska Presentations from the

cell biochemistry

lectures

www.ugd.edu

.mk

e-learning

2010

3. B. Gorgeska, D

Gogieva, K Smilkov

Internal script www.ugd.edu

.mk

e-learning

2010

22.2.


No. Author Name Publisher Year

http://www.ugd.edu.mk/




1. Karlson Peter BIOKEMIJA udžbenik

za studente

tehnološkog,

prehrambeno-tehnol.,

biotehnol., prirodosl.-

mat., medicinskog i

farmaceutsko-biokem.

fak. - 8.izd. prema

12.nj.

Školska

knjiga–

Zagreb,

Превод:

Kurzes

Lehrbuch der

Biochemi

1993

2. Stryer, Lubert BIOKEMIJA Školska

knjiga–

Zagreb,876

str. Превод:

Biochemistry,

2nd ed. или

L. Stryer:

BIOCHEMIS

TRY, W. H.

Freeman,

New York,

2006

1991

Annex No.3

Course Programme- first/second/third cycle studies

1. Course title Good Laboratory Practice

2. Code








third cycle)

First cycle


third semester

7. Number of

credits

5

8. Lecturer/ Instructor PhD. Prof. Biljana Gjorgjeska



The aim is to introduce the regulations, development, meaning and content of quality

systems and good laboratory practice (GLP) with separate processing elements of the

quality assurance system and its importance to the pharmaceutical industry.

11. Course content:

Theoretical instrunction

Introduction (Introduction to course content)

International regulations:

1. WHO recommendations

2. EU - Directives

3. USA - legislation (FDA) - differences in relation to the EU;

4. ISO / IEC 17025

5. Accreditation

Regulation in Republic of Macedonia-compared with international regulations:

1. Drug Law, 2. Regulations; 3.Farmacopea.

Good laboratory practice in pharmacy: in the world (EU, USA) and the requirements

today. Documentation system for quality assurance.


Examples of questions and tasks

Development of practical examples and problems in the implementation of standards of

good laboratory practice. Reviewing the process of introducing, implementation and

accreditation.

Final exercise


Lectures, practical laboratory work, individual assignments, group discussion methods.

13. Total available time 150



teaching,

e-teaching

30


exercises,


work

30

16. Other forms of activities 16.1. Project work 15hours






oral)

10 points









prerequisites

The student is responsible to actively monitor all

the activities for which it wins points which

include participation in the ongoing review of

knowledge, to get a signature and to obtain

necessary number of points to be able to take

the final exam.

Criteria for passing:

• The Assessment method is based on the

cumulation of points won from : lectures,

exercises, colloquiums and seminar paper;

• colloquia are independent of each other, i.e.

taking one is not a prerequisite for taking the

other colloquium;

• The final exam is also not dependent on the

midterm, they are not a requirement for passing

the final exam, but the total number of points

scored, which should not be less than 42 points;



arrange additional colloquium, when there is

sufficient number of candidates



instruction

Continuous checking of knowledge:

two written tests (colloquia)

Final exam: written and oral

Self evaluation

22.

Literature

22.1.

Required literature


1. B. Gorgeska Lecture presentations www.ugd.edu

.mk

е-learning

2. Handbook: good

laboratory practice (GLP):

quality practices for

regulated non-clinical

research and

development -2nd ed

World Health

Organization

2009

3. ЗАКОН ЗА ЛЕКОВИТЕ И

МЕДИЦИНСКИТЕ

ПОМАГАЛА

Сл. весник

на РМ

4. Quality assurance of

Pharmaceuticals, Volume

2, 2nd updated edition,

Good manufacturing

World Health

Organization

2007



practices

and inspection

5.

22.2.



1. Б. Ѓорѓеска ˝Документациона основа

за безбедно управување

со квалитетот во

Национална

лабораторија за лекови˝

www.ugd.edu

.mk

2013

2. Leonard Steinborn GMP/ISO

Quality Audit Manual for

Healthcare Manufacturers

and Their Suppliers

CRC Press

LLC

2003

3. Comparison Chart of FDA

and EPA

Good Laboratory Practice

(GLP) Regulations

and the OECD Principles

of GLP

U.S.

Department

of Health and

Human

Services

Food and

Drug

Administratio

n

Office of

Regulatory

Affairs (ORA)

2004



Annex No.3


1. Course title Analytical chemistry

2. Code




department)




third cycle)

First cycle


forth semester

7. Number of

credits

5




The aim is to introduce the fundamentals of analytical chemistry, including chemical

analysis, chemical equilibrium, settling reactions, qualitative and quantitative chemical

analysis and titrimetric analyses.

The purpose of practical work (exercise) is for students to gain knowledge in the field of

chemical analysis. During the laboratory work the students produce chemical analysis,

calculate results and resolve chemical problems.

11. Course content:


1. An introduction to teaching course content. Subject and tasks of analytical chemistry

2. Theory of electrolyte dissociation, degree of el. dissociation, activity in the ions.

Brenshted-Lori, Arenious and Louis theories

3. Water ionization and hydrogen indicator, salt hydrolysis, pH measurement

4. Bufferes, pH of solutions (weak, strong electrolytes and amfolites)

5. Equilibrium in heterogeneous systems, precipitation, dissolution of sediments,

6. Complex compounds balance.

Classical analytical methods

1. Quantitative analysis. Volumetry and titrimetric analyses: definitions, principles and

classification

2. Gravimetry: Principle of operation, types of sediments and measuring mass

Modern analytical methods

1. Separating techniques and fundamentals of chromatography , liquid –liquid

extraction, gas chromatography , HPLC, electrophoresis and electrochromatography .

2. Spectrometric techniques: introduction, radiation and electromagnetic energy level

atomic and molecular spectroscopy, emission spectrometry : flame atomic emission

spectrometry ; spectrometry with inductively coupled plasma .

3. Absorption spectrometry: atomic absorption and atomic fluorescence spectrometry,

ultraviolet and visible spectroscopy, mass spectrometry: basic principles and

application of the technique.

4. Fundamentals of electrochemical methods : potenciometry and pH-metry


1. Solutions, quantitative expression of the composition of the solutions, chemical

equilibrium in homogeneous systems

2. pH , ionic product of water

3. Buffers

https://www.google.com/search?q=PH+hydrogen+indicator&biw=1280&bih=927&tbm=isch&tbo=u&source=univ&sa=X&ei=YIZWUrGIGsnNswaew4HwDg&ved=0CEEQsAQ

4. Product solubility

5. Equilibrium in solutions of weak acids and weak bases

6. Qualitative analysis of cations

7. Qualitative analysis of anions

8. Quantitative analysis ( volumetric methods) – alcalimetry and argentometry

9. Quantitative analysis ( volumetric methods) – complexometry and permanganometry

10. Planar chromatographic methods

11. Spectrophotometric methods : Beer - Lambert law

12. Electrochemical methods : potenciometry and amperometry






teaching,

e-teaching

30 hours


exercises,


work

30 hours







oral)

10 points









prerequisites

Two partial exams (colloquia) on theoretical

lectures and laboratory exercises. The final

assessment is defined by student’s activity and

the knowledge of theoretical lectures, laboratory

exercises and quality of seminar paper.



instruction




Self evaluation

22.

Literature

22.1.

Required literature


1. D. Kelly, P.J, Hains, Analytical chemistry Publishers

Limited,

2002

BIOS Scientific.

Oxford, UK

2. B. Daglas, A. Scug,

Donald M West F.

James Holer Stanley R.

Crouch.

Introduction to

analytical chemistry

Просветно

дело Скопје

(translated to

Macedonian)

2009

22.2.



1. Valentin Mirceski

Analiticka hemija za

farmacevti

2.

3.

Annex No.3


1. Course title Introduction to transfusiology

2. Code








third cycle)

First cycle


forth semester

7. Number of

credits

5

8. Lecturer/ Instructor Prof. Dr. Nikola Kamcev



The aim is to introduce student to the fundamentals of transfusiology.

11. Course content:


• Transfusiology as a science

• Blood donation process

• Special types of blood donation

• ABO groups - blood system

• Rh system and other blood group systems

• Transmission of infectious agents by transfusion

• Ethical aspects related to blood transfusion

• Pre-transfusion testing

• Blood components

• Adverse effects of transfusion

• Diagnosis and treatment of clinical conditions with defects of coagulation factors


• Acceptance and testing of blood donor

• Venepuncture

• Treatment of donated blood

• Determination of blood group

• Determination of the Rh system

• Cross-testing between the blood samples of the patient and donor

• Blood plasma components

• Basic tests of hemostasis

• Control of oral anticoagulant therapy

• Transfusion-transmissible infections (tests)

• Imunohematological analysis

• Promotion of blood donation






teaching,

e-teaching

30 hours


exercises,


work

30 hours







oral)

10 points









prerequisites

At least 42 points acquired.



instruction

Self-evaluation

Annex No.3


1. Course title Medical cytology

2. Code






Faculty of medical science


third cycle)

First cycle


forth semester

7. Number of

credits

4




The purpose of this subject is for the students to get familiar whit the routines,

techniques and methods that are related whit microscopy as well to get basic

knowledge from the area of cell biology. They study the cell chemical methods used in

medicine and are especially important during diagnosing certain diseases. With this the

students develop specific competences in development of scientific research

procedures that are used with microscopy, building an analytical approach that will be

used during the diagnostic of certain hereditary and nonhereditary diseases. In the

Cytology part the students develop basic theoretical foreknowledge for the cell and for

the cell organelles, especially the nucleus structure and constitution of the whole

genetic material. All membrane and nonmembrane organelles are included with special

emphasis on their functions and associated pathologies. In this way the students will be

able to identify a normal cell from physiologically amended cell. Also the students have

a goal to get familiar whit the structure and function of macromolecules in the living cell

and the clinical-biochemical correlations in it. All the theoretical knowledge that the

students gather in this subject is controlled and determined with practical laboratory

work and practice.

11. Course content:

Review the cell and cytoplasm

Chemical composition of the cell;

Cell membrane structure;

Transport through the cell membrane;

Endoplasmic reticulum structure;

Golgi apparatus structure;

Mitochondrial structure;

Structure of lysosomes and peroxisomes;

Nucleus structure

Cell division;

Cell differentiation.

Apoptosis;


Lectures,exercises,research and practical activities




teaching,

e-teaching

30 hours


exercises,


work

15 hours







oral)

10 points









prerequisites

42 points acquired



instruction

Evaluation of the knowledge is continuous and it

is accomplished by evaluating seminar papers,

essays, oral presentations, participation in

discussions, tests and other ways of testing the

knowledge. On the basis of all actions applied

and evaluated, including the final exam, it

evaluates the quality of instruction.

22.

Literature

22.1.

Required literature


1. Michael H..Ross;

Pavlina Vojnic

Cell and molecular

biology


2. Tomas Pollard; William

Earnshaw

Cell Biology Elsevier 2008

3. Liljana Bozinovska Physiology of the

eukaryotic cell

22.2.



1. Danica Roganivik -

Zafirova

Cytology

Annex No.3


1. Course title Biostatistics

2. Code








and third cycle)

First cycle

6. Academic year / semester Second year / forth

semester

7. Number of

credits

4

8. Lecturer/ Instructor Prof.Milka Zdravkovska, MD, PhD


10. Course objectives (competencies): Acquiring knowledge about the basics of medical

biostatistics - ways of collecting data, grouping the data series and their statistical table

and graph.

11. Course content:


1. Concept and development of bistatistics ; statistical table , sample units, types and

properties of statistics , statistical series (atributiv, numerical, spatial, temporal)

2. Methods of data collection: census, registration and preparation of reports, method

of questionnaire - a survey.

3. Tabular and graphical presentation of statistical series. Analysis of the structure of

the series atributive tokens (ie, proportions, rates and indices) .

4. Analysis of the structure of the series with numerical characteristics (mean, median,

mode).

5. Measures of variability: mean deviation, variance and standard deviation , coefficient

of variation .

6. Hypotheses / testing of hypotheses, analysis of statistical relationships in series with

atributive marks (x 2 test and contingency coefficient) .

7. Analysis of relationships in series with numerical characters (Pearson- correlation

coefficient, Spearman- rank correlation coefficient and multiple correlation ) .

8. Method of sampling , estimation of parameters of the sample ( parameter π and the

parameter μ)

9. Testing the significance of differences between the two environments and arithmetic

between two proportions (Student- t t- test for independent and dependent samples ) .

10. Examination of the dynamics of phenomena ( trend , seasonal index)

11. Vital statistics, concepts and sources in demographic statistics.

12. Application of computer science technology in medicine.


1. Plan for stastistic research.

2. Indices of dynamics with constant and variable basis.

3 Calculating the arithmetic mean in nongroup data, grouped in the interval group and

the group without grouped interval.

4. Calculating the median and the mode for nongrouped and grouped data.

5. Standard deviation in nongrouped and grouped data; Coefficient of variation.

6. Calculating the expected frequencies and x2 test.

7. Pearson-correlation coefficient of correlation in nongroup data.

8. Estimation of parameters of the sample (π parameter and the parameter μ)

9. Student-test for two independent large samples and in two proportions.

10. Linear trend of time series (for odd and even number of years) Seasonal index.

11. Calculating birth rates, fertility, mortality, morbidity, natural population growth.

12. Presentation of the statistical program.


Small group work, homework, practical work, project assignments, discussion.




e-teaching

30 h

15.2. theoretical and practical exercises,


15 h

16. Other forms of activities 16.1. Project work 15 h


16.3. Homework 60 h












prerequisites

Scored at least 42 points on all grounds (lectures,

tutorials, colloquia, seminar paper)


21. Method ofmonitoringthe quality of

teaching

Self evaluation

22.

Literature

22.1.

Required literature


1.

2. Jamie F.. Dzhekel,

David L.. Katz, Joan J..

Elmore, Dorothea MJ

Wilde

Epidemiology,

Biostatistics and

Preventive Medicine

Springer 2010

3.

22.2.



Annex No.3


1. Course title Instrumental analysis

2. Code








and third cycle)

First cycle


semester

7. Number of

credits

4

8. Lecturer/ Instructor Prof.Dr. Rubin Gulaboski


10. Course objectives (competencies): Acquiring knowledge about the basics of

instrumental analysis.

11. Course content:

UV-VIS spectrophotometry, Atomic absorption and Emission spectrometry,

Luminiscent methods, Infrared spectrometry, and Turbidimetrics and Nefelometrics,

Refractometrics and Polarimetrics, Mass spectrometry, Centrifugal methods,

Chromatographic methods, General part, Liquid and Gas chromatography.

Electrophoretic techniques, Potentiometric Electrochemical Techniques






e-teaching

30 h



30 h



16.3. Homework 70 h












prerequisites




21. Method ofmonitoring the quality of

instruction

Self evaluation

22.

Literature

22.1.

Required literature

no Author Name Издавач Година

1. David Harvey Modern analytical

chemistry

Prosvetno

delo

2009

2. А.Veljanovski Instrumentalni metodi

vo farmacevtskite

analizi

Studentski

zbor

1995

3.

22.2.


no Author Name Publisher Year

Annex No.3


1. Course title Nutritionism - modeling and optimisation

2. Code








and third cycle)

First cycle


semester

7. Number of

credits

4

8. Lecturer/ Instructor Prof.Dr. Nako Taskov


10. Course objectives (competencies): Through lectures, exercises-workshops,

consultations and prepared seminar paper students shall meet and engage in different

forms, methods, learning strategies and academic research to acquire the theoretical

and practical knowledge related to nutrition.

11. Course content :

1. Basic ingredients

2. Factors that determine nutrition

3. Making the daily meal

4. Energetic metabolism

5. Digestibility of the food

6. Quality of nutrition

7. Quality of food products

8. Losses of the food that can not be reused

9. Losses in thermal processing of foods

10. Nutrition according to age and physical activity

11. Nutrition as prevention of illness

12. Prepared food, organoleptic characteristics






e-teaching

30 h




16.2. Individual work

16.3. Homework 20 h












prerequisites




21. Method ofmonitoringthe quality of

instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Taskov N. “Ishrana i dietetika”

Internal script

22.2.



1. Garrow S. J.,

Ralph A., William

Philip Trehearne

James,

„Human Nutrition and

Diet“

Elsevier 2000

2. Rosic M., Rosic

G., Angelkovic I.,

Principi ishrane i

rekreacije

University

Singidunum,

Belgrade

2009

3.

http://books.google.mk/url?id=a-pSOMMaoaUC&pg=PP1&q=http://www.elsevierhealth.com&clientid=ca-print-elsevier_health_uk-elsevier&channel=BTB-ca-print-elsevier_health_uk-elsevier+BTB-ISBN:0443056277&linkid=1&usg=AFQjCNFjdVCajcQPAWtN71YJKp6RvgGTMg&source=gbs_pub_info_r

Annex No.3 Course Programme - first cycle of studies

1. Course title Public Health

2. Code


4. Organiser of the study

programme(unit i.e. institute,

department)



cycle)

First cycle

6. Academic year / Semester Second year /

fourth semester

7. Credits 2

8. Lecturer/ Instructor Professor D-r Gorgi Sumanov


10. Course objectives (competencies): Acquisition of basic knowledge of the role, need

and content of public health; certain infectious and chronic non infectious diseases as a

public health problem.

11. Course content:


1. Introduction to public health; Organizational setup and goals;

2. Intestinal infectious diseases – public health aspects

3. Respiratory infectious diseases - public health aspects

4. Transmissive infectious diseases - public health aspects

5. Blood and sexually transmited infectious diseases - public health aspects

6. Intrahospital infections; antibiotics resistance as a public health problem

7. Periods of occurrence of chronic degenerative diseases and level of prevention

8. Cardiovascular and cerebrovascular diseases - public health aspects

9. Diabetes and its chronic complications as a public health problem

10. Neoplasms - public health aspects

11. Chronic obstructive pulmonary disease and ulcer disease

12. Addiction diseases as a public health problem

12. Course methodology: Lectures, group discussion methods, individual assignments,

seminar papers;

13. Total time available 60 hours

14. Distribution of the available time 2+0+1


education

30 hours

15.2. Practice(laboratory

theoretical), seminar

papers, teamwork

16. Other forms of activities 16.1. Project work 0




17.1. Tests and a final oral exam 70 points

17.2. Seminar paper/project ( presentation: written and oral ) 10 points


18. Grading system (points / grade) tо 50 points 5 (five) (F)

from 51 tо 60 points 6 (six) (E)

from 61 tо 70 points 7 (seven) (D)

from 71 tо 80 points 8 (eight) (C)

from 81 tо 90 points 9 (nine) (B)

from 91 tо 100 points 10 (ten) (A)


prerequisites

For a signature - presence of at least 7 (60%)

lectures; For the final exam - scored at least 42

points on all grounds;



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Teodor T. Tulcinski,

Elena A. Varavikova

New public health NIP

Studentski

zbor - Skopje

2003

2. Lence Mircevska, Donco

Donev, Ilija Gligorov

Zdravstveno vospitanie Bitola 2006

3. D.Donev, G.Pavlekovi,

l.Z.Kragelj

Health promotion and

disease prevention

Hans Jacobs

publishing

company




1. Course title Intrahospital infections

2. Code




department)



5. Leve of studies (first, second, third

cycle)

First cycle

6. Academic year / Semester Second year /

forth semester

7. Number of

Credits

2

8. Lecturer/Instructor Professor D-r Velo Markovski


10. Course objectives (competencies): To realize the seriousness of the intrahospital

infections as a huge public health problem and to understand the importance of the

control of the intrahospital infections; To know how to define and recognize the

intrahospital infections and the risk factors which influence or are dominant for their

appearing; To acquire knowledge and skills for control, suppression and prevention of

the intrahospital infections;

11. Course content:


1. Definition and meaning of the intrahospital infections

2. Need for epidemiological approach in the control of the intrahospital infections

3. Etiology of the intrahospital infections

4. Occurrence and transmission of the intrahospital infections

5. Types of intrahospital infections

6. Disinfection and sterilization

7. Medical waste and intrahospital infections

8. Prevention of intrahospital infections

9. Types of epidemiological supervision and control of intrahospital infections

10. Organizational placement and law regulative in the control of intrahospital

infections

11. The importance of team work and interdisciplinary approach in control of

intrahospital infections

12. Elements of the control of intrahospital infections

Skills for controlling intrahospital infections:

Appropriate hands hygiene; Control of the hands hygiene of the health care

workers;

Appropriate disinfection of the working surfaces and objects in the hospital

environment;

Appropriate taking of a swab from nose, throat and wound;

Appropriate processing / taking material for microbiological diagnoses from

patients with intrahospital infections;

Being critical in defining and taking the materials for microbiological

diagnoses;

Appropriate packing and transporting of the samples for microbiological

diagnoses;

Procedures in case of occurrence / isolation of MRSA;

Appropriate taking of material for air control in the hospital environment (

operation rooms, intensive care units);

Group discussion – procedures and suggested measures for suppression

and prevention of the intrahospital infections in certain situations (according

to certain examples of intrahospital infections);

Working in small groups/teams - procedures and suggested measures for

suppression and prevention of the intrahospital infections in certain

situations (according to certain examples of intrahospital infections);

Filling a unified application for each patient with intrahospital infection;

Defining incidence and prevalence rate of intrahospital infections

12. Course methodology: Lectures, group discussion methods, individual assignments,

seminar papers;




education

30 hours

15.2. Practice (laboratory


papers, teamwork

/

16. Other forms of activities 16.1. Project work 10hours





17.2. Seminar paper/project ( presentation: written and oral) 10 points


18. Grading system (points / grade) to 50points 5 (five) (F)

from51 to60points 6 (six) (E)

from61 to70points 7 (seven) (D)

from71 to80points 8 (eight) (C)

from81 to90points 9 (nine) (B)

from91 to100points 10 (ten) (A)


prerequisites





21. Method of monitoring the quality of Self evaluation

instruction

Annex No.3


1. Course title Introduction to clinical practice

2. Code






Faculty of Medical sciences


third cycle)

First cycle

6. Academic year / semester 2012-2013

V

7. Number of

credits

5

8. Lecturer/ Instructor Prof. Nikola Kamcev



The purpose of this course is to familiarize students with theoretical and practical

knowledge in clinical practice. Studying this course, students will gain knowledge

about the basic types of laboratories, the behavior and personal protection in them.

They will learn about how to properly take blood, urine and fluid from patients

hospitalized and treated in clinical departments, to handle medical waste, and also to

master the ways of disinfection and sterilization. They will study the basic

characteristics of laboratory equipment and laboratory techniques to learn how to

safely and properly operate them.

The main task of this course is for students to acquire theoretical and practical

knowledge about personal safety and safe behavior in laboratory and clinical

departments. Also objects of study of this subject are plans for emergency situations

and emergency procedures as chemical, electrical and fire safety.

They need to learn how to assess the health status of patients and to determine the

vital parameters (heart rate , arterial pressure , breathing , to learn how to take

different biological materials for analysis , and to learn the basic methods of care and

nutrition patients).

11. Course content:

1. History of clinical practice

2. Types of laboratory facilities according to biosafety

3. Microbiological risk assessment

4. Ethic rules

5. Projecting of laboratory and laboratory equipment

6. Clinical laboratory techniques for taking biological material for analysis

7. Medical waste handling

8. Accreditation and certification


10. Contingency plans and emergency procedures

11. Transport of infected material

12. Checklist for biosafety

13. Transmission of infectious agents

14. Ethical aspects related to blood transfusion

15. Clinical laboratory diagnosis of clinical conditions

12. Course methodology: theoretical work, interactive lectures, individual rasks, seminar

paper




teaching,

e-teaching

30 hours


exercises,


work

15 hours







oral)

10 points





A 8 (eight) (C)




prerequisites

Attendance and activity on lectures and

tutorials, satisfactory colloquia



instruction

Self-evaluation

22 Literature


1. Проф. Д-р

Никола

Камчев

Авторизирани

предавања

авторот 2013

22.

Literature

22.1.

Required literature


1. C. Glen Mayhall Hospital Epidemiology

and Infection Control,

Third Edition,

Philadelphia

, USA

2004

2.

3.

22.2.



Annex No.3


1. Course title Introduction to infectious diseases

2. Code








third cycle)

First cycle

6. Academic year / semester 2012-2013

VI

7. Number of

credits

4

8. Lecturer/ Instructor Velo Markovski,Phd



To master the basic elements of diagnosis, therapy and prophylaxis of infectious

diseases.

11. Course content:


1. Infection, infectious disease (basic features), temperature, species and regulation

2. Principles of diagnosis, therapy and prevention of infectious diseases

3. Fundamentals of Immunology of Infectious Diseases

4. Fundamentals of gastrointestinal infections; dehydration

5. Epidemiological and clinical features of hepatitis

6. Viral rush diseases: varicella-zoster, measles, Rubeola, Flu

7. Parotitis epidemic. Mononucleosis

8. Respiratory infections

9. Characteristics of zoonoses

10. Infectious diseases of the CNS

11. HIV infection


12. Acceptance of patient with an infectious illness and accommodation in isolation

13. Adequate protection of medical personnel and disposal of infectious waste

14. Sampling of biological material for examination

15. Microbiological and serological analyzes in infectology

16. Diagnostic and therapeutic protocol for infectious diseases

17. Registration and check of an infectious diseases

18. Treatment of patient with hepatitis

19. Treatment of the patient with rush of infectous origine

20. Lumbar puncture

12. Course methodology: theoretical and practical work




activities

15.1. lectures / theoretical

teaching,

e-teaching

30 hours


exercises,

30 hours


work







oral)

10 points





A 8 (eight) (C)




prerequisites

Attendance and activity on lectures and

tutorials, satisfactory colloquia



instruction

Self-evaluation

22.

Literature

1.

22.1.

Required literature


1. Authorized

lecture-

1. Faculty of

Medicine-

University

Goce

Delchev-

Stip

2. Infectious

Diseases(selected

chapters),

Faculty of

Medicine, Skopje

3.


Annex No.3


1. Course title Clinical and toxicological analysis

2. Code






Faculty of Medicine


third cycle)

First cycle

6. Academic year / semester 2012/2013 7. Number of

credits

4

8. Lecturer/ Instructor Associated professor PhD Vesna Kostik


10. Course objectives (competencies): Basic principles of toxicological investigation of

certain groups of poisons, their physical and chemical properties, toxicological

importance, toxicity for humans, antidotes, symptoms and medical treatment,

biotransformation in human body, investigation of certain group of poisons in biological

fluids and tissues and other types of materials, biomarkers of poisons and their

determination in biological fluids and tissues.

11. Course content:

1. Toxicology – Division of toxicology, types of toxicological approaches, definition

of term “poison”, toxic and lethal dose, classification of poisons, ration between

dose and effect, characteristics of exposure to toxic substances, ways of

exposure, ways of ingestion of poisons and their impact on human body,

metabolism of poisons in human body, excretion of poisons from human body,

development of tolerance to poisons, accumulation of poisons, classification of

poisonings, antidotes. Performance of toxicological analysis (common rules and

safety rules in toxicology analysis, purity of reagents), group of gases: carbon

monoxide, carbon dioxide, chlorine, hydrogen sulphide, cyan hydrogen.

2. Volatile organic compounds: toxicological importance, physical and chemical

properties, mode of action, symptoms of poisoning, the importance of laboratory

tests in diagnosis of type of poisoning, toxicity of organic solvents, specific

effects of organic solvents, ethanol, methanol, acetic acid, aliphatic

hydrocarbons: hexane, carbon disulphide, dichloromethane, chloroform,

tetrachlorethane, trichloroethylene.

3. III group of poisons (mineral poisons): Types of mineralization of organic

material: dry mineralization, mineralization using low temperatures using

oxidising agents (wet mineralization), and other methods of mineralization

(mineralization using microwaves).

4. Arsenic: Toxicological importance, types of poisonings, toxicologically important

arsenic compounds – arsenic trioxide, arsenates, arsenic hydrogen, arsines,

organic arsenic compounds, toxicity of organic compounds, symptoms of

poisoning, impact on inner organs, antidotes, investigation – classical

techniques, modern techniques for arsenic determination of arsenic in various

types of matrixes (FIAS), interpretation of the results.

5. Antimony: Toxicological importance, physical and chemical properties,

toxicologically important compounds, toxicity, symptoms, antidotes,

determination, interpretation of the results.

6. Mercury: Toxicological importance, physical and chemical properties,

toxicologically important compounds, toxicity, symptoms, antidotes, protection

of professional poisonings, determination in different types of matrixes,

interpretation of the results.

7. Lead: Toxicological importance, physical and chemical properties,

toxicologically important compounds, accidental and professional poisoning,

toxicity, symptoms, antidotes, protection of professional poisonings,

determination in different types of matrixes, interpretation of the results.

8. B. Mineral poisons which are analysed without prior mineralization of organic

material: alkaline compounds, potassium chlorate, sodium chlorate, nitrites,

fluorides, strong mineral acids – sulphuric acid, nitric acid, hydrochloric acid

(toxicological importance, physical and chemical properties, toxicologically

important compounds, toxicity, symptoms, antidotes, protection of professional

poisonings, determination in different types of matrixes, interpretation of the

results).

9. IV group of poisons which are isolated from organic material with liquid-liquid

extraction – Common methods of extraction.

10. A. Poisons which are isolated from acid solutions: glycosides (digitalis

glycosides, , barbiturates, salicylic acid and its compounds, oxalic acid,

dinitrophenol, picric acid (toxicological importance, physical and chemical

properties, toxicologically important compounds, toxicity, symptoms, antidotes,

determination in different types of matrixes, interpretation of the results).

11. B. Poisons which are isolated from alkaline solution: opium alkaloids, morphine

and morphine derivates, atropine, hyosciamine, scopolamine, cocaine,

synthetic local anaesthetics, aconitine, veratrine, physostigmine, nicotine,

coniine, colchicines, pilocarpine, alkaloids of secale cornutum, solanine

(toxicological importance, physical and chemical properties, toxicity, symptoms,

antidotes, determination in different types of matrixes, interpretation of the

results).


Lectures (theoretical teaching), theoretical and practical exercises, preparation of

independent seminar paper




teaching,

e-teaching

45


exercises,


work

30



16.3. Homework 55hours




oral)

10 points









prerequisites

Attendance and at leat 42 points from pre-exam

activities



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Milan Jokanovic Toxicology Elit, Medicina,

Belgrade

2001

2. R. Dreisbach,

W.Robertson

Intoxication,

Prevention,

Diagnosis and

Medical Treatment

Savremena

Administracija,

Belgrade

1989

3. Stanley E. Manahan Toxicological

chemistry and

Biochemistry

Third edition

Lewis

Publishers

A CRC Press

Company

Boca Raton

London New

York

Washington,

D.C.

2003

22.2.



1. Danica Prpic-Majic Toxicological and

chemical analysis

Medicinska

kniga

Beograd-

Zagreb

1985

2. Dr. Momcilo St.

Mokranjac

Toxicological chemistry University of

Belgrade,

Faculty of

Pharmacy

1962

Annex No.3


1. Course title Bromatology

2. Code








third cycle)

First cycle


credits

6

8. Lecturer/ Instructor Associated professor PhD Vesna Kostik


10. Course objectives (competencies): Basic principles of bromatology (food chemistry,

classification of food, food products and drinking water, chemical composition of

food, food product and drinking water, analytical methods and techniques used in

food and water analysis.

11. Course content:

1. Bromatology – History of bromatology, definition, objectives of bromatology,

classification of food components, definition of food, classification of food.

2. Energetic value of food. Principles of rational human nutrition.

3. Water for human consumption.

4. Carbohydrates. Oils and fats

5. Proteins

6. Vitamins, Minerals

7. Meat and meat products, Fish Eggs

8. Milk and milk products Cheese

9. Grains

10. Fruits and fruit products

11. Vegetables and vegetable products

12. Honey

13. Coffee

14. Cacao

15. Tea

16. Sugar (sucrose)

17. Salt

18. Vinegar

19. Food Additives

20. Genetically modified food, Food contamination (chemical, microbiological,

radiological)


Lectures (theoretical teaching), theoretical and practical exercises, preparation of

independent seminar paper

13. Total available time 7 ЕCТS х 30 h= 210 h

14. Distribution of available time 45+45+15+25 +80 = 210 h

. Forms of teaching activities 15.1. lectures / theoretical

teaching,

e-teaching

45


exercises,


work

45

16. Other forms of activities 16.1. Project work 15

16.2. Individual work 25

16.3. Homework 80




oral)

10 points









prerequisites

Attendance and at leat 42 points from pre-

exam activities



instruction

Self-evaluation

22.

Literature

22.1.

Required literature


1. Stanimirovic, S BROMATOLOGIJA 1970

22.2.



1. Belitz, HD, Grosch, W. FOOD CHEMISTRY Springer

Berlin, 3 Ed.

2004

2. Coultate, TP FOOD: THE

CHEMISTRY OF ITS

COMPONENTS

Royal Society

of Chemistry

1995

Annex No.3

Course Programme - first cycle studies

1. Course title Laboratory safety

2. Code



program(unit or institute,



Goce Delcev University - Stip



First cycle

6. Academic year / semester Fifth semester 7. Number of credits 4

8. Lecturer/ Instructor Assistant Professor Tatjana Ruskovska, PhD


courses

none


Introduction and training for personal protection when working in the laboratory, risk

assessment and addressing the issues of safety and biological safety in laboratories.

11. Course content:

1. Types of laboratory facilities according to the biological safety

2. Microbiological risk assessment

3. Regulation of behavior

4. Designing laboratories and facilities

5. Laboratory equipment

6. Handling the waste

7. Accreditation and issuance of certificates

8. Laboratory techniques


10. Contingency plans and emergency procedures

11. Transport of infectious material

12. Reviewing a list of biological safety


Work in small groups, seminar paper, practical work, discussion, debate, individual work




activities

15.1. Lectures - theoretical teaching

30 hours

15.2. Exercises (laboratory, theoretical),

seminars, teamwork

15 hours









/grade)








prerequisites

Attendance and scored at least 42 points from all pre-exam

activities.




Self-evaluation

22.

Literature

22.1.

Required literature


1. Nikola Kamcev Safety at work in the

laboratory

UGD 2010

2. Danijela Janikevik

Ivanovska

Lectures 2013

22.2.



1. WHO Biosafety manual WHO 2004

2. JUAT Rules of accreditation JUAT 2002

Annex No.3


1. Course title Clinical microbiology

2. Code





University “Goce Delcev”



third cycle)

First cycle

6. Academic year / semester 2013-2014 / VI 7. Number of

credits

4

8. Lecturer/ Instructor Ass. prof. d-r Vaso Taleski, MD, D-r Sc.



Basic aim of the course programme is to introduce and enable students to acquire

theoretical, practical knowledge, skills and competences in field of microbiology.

11. Course content:


1. Introduction to history and development of microbiology as a science,

significance of microorganisms. Classification of bacteria, taxonomic

categories, nomenclature, size, shape and disposition of bacteria

2. Morphology and structure of bacterial cells: capsule, cell wall, cytoplasmic

membrane, cytoplasm and cytoplasmic inclusions, fimbrae and pili, flagellum,

bacterial spores, bacterial movement. Conditions for growth and multiplication,

growth phases, bacterial colonies

3. Chemical composition of bacteria, metabolism, mechanism of bacterial feeding,

metabolism of energy

4. Metabolism of nucleic acids. DNA replication. Nucleic acids decomposition.

Bacterial genetics. Bacterial phenotype and genotype variations. Gene transfer

5. Spreading of microorganisms. Associations of microorganisms. Pathogenicity

and virulence. Infections and infective diseases. Nonspecific and specific

immunity in humans. Immunotherapy and immune-prophylaxis.

6. Sterilization and disinfection. Antibiotics and chemiotherapeutics.

Microorganism’s resistance toward antibiotics. Side effects of

chemiotherapeutics.

7. Aerobic and anaerobic Gram positive and negative cocci.

8. Gram negative rods. Gram positive rods: sopreforming and non-sporeforming

9. Spiral bacteria. Rickettsia. Mycobacteria. Actinomyces,Nocardia

10. Morphology, structure, classification and multiplication of viruses. Importance of

viral infections

11. Most important DNA and RNA viruses

12. Morphology, structure, classification and multiplication of fungi. Morphology,

structure, classification and importance of parasites


13. Principles of safety in microbiological laboratory. Sampling, packaging and

delivering samples for microbiology testing

14. Microscope and microscopic examinations of microorganisms (light

microscope, fluorescence microscope, electron microscope). Staining of

microorganisms (Gram, Giemsa, Ziehl-Neelsen)

15. Culture media and bacterial cultivation. Identification of bacteria (classical

biochemical reactions, automatic systems for identification)

16. Antibiotic susceptibility testing of bacteria/antibiogram (classical diffusion and

dilution methods, automatic systems, E-test). Hemocultures

17. Microbiological diagnosis of wound infections and respiratory infections

18. Microbiological diagnosis of genital-urinary and sexually transmitted infections

19. Microbiological diagnosis of enteropathogens

20. Classical serologic reactions. Rapid tests

21. Immune-enzymes methods (ELISA, VIDAS)

22. Sterilization and Disinfection

23. Methods of viral diagnosis. Hepatitis markers. Diagnosis of HIV infections.

24. Diagnosis of yeasts and parasites


Methods of oral and visual learning/presentations and practical work in the lab.


14. Distribution of available time 1+2+1 per week


teaching,

e-teaching

15 hours


exercises,


work

30 hours







oral)

10 points

17.3. Attendance and participation during lecturing 10 points

17.4 Attendance and participation during lab practical work 10 points

17.5 Final exam 30 points








prerequisites

Requirements for signature: presence at

lecturing and practical work.

Requirements for final exam: at least 42 points

from two colloquia, presence at lecturing,

practical lab work and seminar paper/project -

presentation. Colloquia are not conditionally

connected. For students with points over 37 and

less than 42, the professor could organize

additional colloquium with maximum of 10

additional points



instruction

Student evaluation

Self-evaluation

22.

Literature

22.1.

Required literature


1. Greenwood D.

et all.

Medical

microbiology

Project of the

Government of the

Republic of Macedonia,

for translation of

vocational and scientific

books

17-

edition,

2006,

Transla

ted in

2011

2.

Panovski N. et

all.

Guest / invited

author: Vaso

Taleski

Medical

microbiology

- Genera

l part

Institute of Microbiology

and parasitology,

Medical faculty Skopje.

2011

3.

Panovski N. et

all.

Guest / invited

author: Vaso

Taleski

Medical

microbiology

- Special

part


and parasitology,

Medical faculty Skopje.

2011

4. Jawetz,

Melnick, &

Adelberg

“Medical

Microbiology”

The McGraw-Hill

Companies

24th

ed.,

2007



1. Milena

Petrovska et all.

“Handbook on

medical

microbiology

and

parasitology”


and parasitology,

Medical faculty Skopje,

5th ed.

2010

2. Vaso Taleski “Microbiology” Authorized

presentations

2008

Annex No.3


1. Course title Clinical biochemistry

2. Code




department)




third cycle)

First cycle

6. Academic year / semester Third year / Sixth

semester

7. Number of

credits

8. Lecturer/ Instructor Prof. Tatjana Ruskovska



Learning the work and methods in the clinical biochemistry laboratories, and principles

for good laboratory practice in laboratory medical diagnostics.

11. Course content:


1. Theoretical basics of clinical enzymology 1.

2. Theoretical basics of clinical enzymology 2.

3. Diagnostic significance of AST, ALT, CK and amylase.

4. Diagnostic significance of γ-GT, LDH and alkaline phosphatase.

5. Microelements, macroelements and acid-base balance 1.

6. Microelements, macroelements and acid-base balance 2.

7. Enzyme and immunochemical methods: theoretical basics.

8. Hormones and tumour markers: methods for their determination and diagnostic

significance.

9. Urine analysis: chemical examination.

10. Urine analysis: examination of the sediment 1.

11. Urine analysis: examination of the sediment 2.

12. Hematology analyzers with threefold and fivefold differential blood test.


1. Determination of the activity of AST and ALT in serum.

2. Determination of the activity of amylase in serum and urine.

3. Determination of the concentration of calcium and phosphorus in serum and

urine

4. Determination of iron concentration and TIBC in serum.

5. Determination of the concentration of sodium and potassium in serum and

urine.

6. Introducing of the principle of the gas analysis method.

7. Determination of cortisol with EIA method.

8. Introduction with the automatic immunohemiluminiscent analyzer functions and

work.

9. Making a complete urine examination 1.

10. Making a complete urine examination 2.

11. Making a hemogram with automatical hematology analyzer.

12. Final exercise.



- Interactive teaching: Lectures in large groups with discussions and engaging

the students.

- Multimedia teaching.

- E-learning.

- Individual consultations with students and consultations in groups.


- Practical laboratory exercises in small groups.

- Auditoria exercises.

- Visiting clinical and biochemical laboratory and demonstrating the operation of

automatic biochemical analyzer.

- Final exercise.


14. Distribution of available time 24 hours of theoretical tuition+24 hours of

practical tuition+12 hours of other forms of

activities / per week


teaching,

e-teaching

45 hours


exercises,


work

30 hours







oral)

10 points









prerequisites

Attendance and at least 42 points acquired from

pre-exam activities



instruction

Self-evaluation

22.

Literature

22.1

.

Required literature


1. Carl A. Burtis, Edward

R. Ashwood, David E.

Bruns

TIETZ, Fundamentals

of Clinical Chemistry,

6th edition

Saunders,

Elsevier

2008

2. Рушковска Татјана Clinical biochemistry Script for

intern use

2010

3. Мајкл Л. Бишоп,

Едвард П. Фоди,

Лари Е. Шоеф

Clinical chemistry (

principles, procedures

and correlations ) –

Fifth edition

Prosvetno

delo, Skopje

Translated

book –

Project of the

Government

- Republic of

Macedonia

2009

4. Александар К.

Брауни, Џон К.

Керноан

Medical biochemistry Translated

book –

Project of the

Government

- Republic of

Macedonia

22.2

.



Annex No.3


1. Course title Clinical transfusiology

2. Code








third cycle)

First cycle

6. Academic year / semester Third year /

Sixth semester

7. Number of

credits

4

8. Lecturer/ Instructor Prof. D-r Nikola Kamcev



Gaining theoretical and practical knowledge in the field of clinical transfusion which

will allow to overcome the basics of genetics and immunology in transfusion, blood

group systems and their clinical significance, receiving blood products and their

clinical use, treatment with blood and blood products in surgery, gynecology, neonatal

period, a syndrome of massive transfusion, transfusion of apheresis application and

the basic principles of the haemostasis laboratory and clinical diagnosis of

hemorrhagic and thrombotic diseases, their prevention and treatment as well as

transfusion aspects in tissue and organ transplantation.

11. Course content:


1. Basics in clinical transfusion

2. Basics of genetics and immunology in transfusion

3. Blood group systems and their clinical significance

4. Immunoserology in clinical practice

5. Blood and blood products therapy.

6. Diagnosis of haemorrhagic syndrome.

7. Chemotherapy in patients with impaired haemostasis

8. Massive transfusion syndrome

9. Aspects of blood transfusion in neonatal period

10. Transfusion of apheresis

11. Cryoconservation of blood cells

12. Transplantation of stem cells and HLA system



the students.


- E-learning.



14. Distribution of available time 1 + 2 + 1


teaching,

e-teaching

15 hours


exercises,

30 hours


work







oral)

10 points









prerequisites

Attendance and at least 42 points acquired

from pre-exam activities



instruction

Self-evaluation

22.

Literature

Required literature


1. Vukman Gligorovikj,

Bela Balint

Clinical transfusion Belgrade 1998

2.

3.

Milenka Blagoevska

Prof. D-r Nikola Kamcev

Transfusion

Authorized lectures

Skopje 2011

2012


1. Course title Methodology of scientific research in Health Care

2. Code




department)


Department of Public Health and Health Protection


cycle)

First cycle

6. Academic year / Semester Fourth semester 7. Number of ECTS

credits

4

8. Lecturer/Instructor Professor D-r Gorgi Sumanov


10. Course objectives (competencies): Acquiring knowledge for the basic methods and

methodology of scientific research; Using biomedical databases and practicing evidence

based on medicine; Acquiring skills for doing researches; Implementation of a research

project; Rules for preparation of a manuscript for publication of the results of a scientific

research; Rules and preparation for a successful presentation of a scientific labour in the

form of oral or poster presentation.

11. Course content:


1. Basic terms of science and scientific method

2. Ethics and responsible behavior in the scientific research

3. Epidemiological methods in the scientific research

4. Types of researches – Design of studies

5. Using biomedical databases and practicing evidence based on medicine

6. Strategies for searching literature

7. Planning and implementation of scientific research

8. Scientific labour – classification of the papers

9. Parts of scientific labour

10. Preparing for manuscript and publication

11. Quoting references

12. Writing style and presentation of the scientific labour


1. Ethics in the scientific research: case reports and discussion

2. Internet research – using biomedical databases

3. Strategies for searching literature

4. Critical analyses of a paper (example from published papers)

5. Planning a research

6. Ways of collecting information - constructing a questionnaire

7. Project assignment for a scientific research project for a given hypothesis - small

groups work

8. Presentation of the project assignments– critical analysis

9. Presentation of the project assignments– critical analysis

10. Independently making an abstract from published papers (in extenso)

11. Presentation of abstracts – critical analysis

12. Oral/Poster presentation of the scientific labour

12. Course methodology: Lectures, exercises, group discussions methods, individual

assignments, seminar papers, presentation of scientific papers;


14. Allocation of the available time 2+1+1


education

30 hours

15.2. Practice (laboratory


papers, teamwork

15 hours






17.2. Seminar paper/project ( presentation: written and oral ) 10 points


18. Grading system (points / grade) tо 50points 5 (five) (F)

from51 tо 60points 6 (six) (E)

from61 tо 70points 7 (seven) (D)

from71 tо 80points 8 (eight) (C)

from81 tо 90points 9 (nine) (B)

from 91 tо 100points 10 (ten) (A)


prerequisites






instruction

Self evaluation

Annex No.3


1. Course title Nuclear medicine

2. Code








third cycle)

First cycle

6. Academic year / semester Third year / Fifth

semester

7. Number of

credits

4

8. Lecturer/ Instructor Doc. D-r Zdenka Stojanovska



11. Course content:


1. Physical basics of nuclear medicine.

2. Basics of radiopharmacy.

3. Nuclear and medical investigations in haematology.

4. Nuclear and medical investigations in cardiology.

5. Nuclear and medical investigations in nephrology.

6. Nuclear and medical investigations in GIT system.

7. Nuclear and medical investigations in hepatobiliary system

8. Nuclear and medical investigations in endocrinology.

9. Nuclear and medical investigations in neurology and psychiatry.

10. Nuclear and medical investigations in oncology

11. Therapeutic application of radionuclides.




the students.


- E-learning.



- Practical laboratory exercises in small groups.

- Auditoria exercises.

- Visiting clinical and biochemical laboratory and demonstrating the operation of

automatic biochemical analyzer.

- Final exercise.


14. Distribution of available time


teaching,

e-teaching

30 hours


exercises,


work

15 hours







oral)

10 points









prerequisites





instruction

Self-evaluation

22.

Literature

Required literature


1. O. Vaskova, S. Miceva

Ristevska, D. Pop

Gjorcheva, D.

Miladinova, S.

Loparska, E. J.

Ivanovska

Fundamentals of

Nuclear medicine

Skopje 2008

Annex No.3


1. Course title Immunological laboratory techniques

2. Code








third cycle)

First cycle

6. Academic year / semester Third year /

Sixth semester

7. Number of

credits

4

8. Lecturer/ Instructor Prof. D-r Darko Bosnakovski



Introduction to basics of laboratory techniques in immunology.

11. Course content:


1. Introduction to Immunology - immune system , types of immunity

2. Antigens, antibodies (immunogenicity and antigenicity), structure, classes and

subclasses, interactions.

3. Methods of separation of immune complexes, Methods of precipitation - gel ,

radial immunodiffusion

4. PAGE- electrophoresis, western blot

5. Methods of direct and indirect immunofluorescence

6. ELISA and RIA

7. Methods of selective separation of cells - filtration through cotton , separation

by density gradient

8. FACS

9. Agglutination methods - direct and indirect Coombs test

10. Determination of blood groups

11. Monoclonal antibody - methods of obtaining and applying

12. Labelling of antibodies for diagnosis and therapy of malignant diseases



the students.


- E-learning.



14. Distribution of available time 2 + 1+ 2


teaching,

e-teaching

30 hours


exercises,


work

15 hours







oral)

10 points









prerequisites





instruction

Self-evaluation

22.

Literature

Required literature


1. Richard A. Goldsby,

Thomas J. Kindt,

Barbara A. Osborne,

Immunology Translated

book from

Government

2012

Janis Kuby of R.

Macedonia

Annex No.3


1. Course title Evaluation of instruments, methods and reagents

2. Code








third cycle)

First cycle


credits

2


9. Required prerequisite courses Prerequisite for entering the subject 1: Listened

to Analytical chemistry 1 and 2, Instrumental

pharmaceutical analysis


The aim of the study of subject Evaluation of instruments, methods and reagents in the

Faculty of Medical Sciences in Study Programme of Pharmacy is to explain the

principles of the spectrophotometric, electrochemical and thermo analytical methods

and the principles of validation of their use. To explain the principles of the system of

validation of iinstruments, methods and reagents and to present some practical cases.

11. Course content:


Quality control of analytical methods. Theoretical basis and analytical importance of

spectrophotometric, electrochemical and thermo analytical methods for analyses in

general analytical and biochemical practice.

Spectroscopic methods for analyses, introduction, UV-Vis spectrophotometry, AAS,

calibration of instruments and validation of methods. Electrochemical methods,

introduction, electrogravimetry, ion selective electrodes, calibration of instruments and

validation of methods. Thermo analytical methods, introduction, thermo gravimetric

analyses, differential calorimetric analyses, calibration of instruments and validation of

methods.

Chromatographic (HPLC, GC, TLC, HPTLC, gel and ion chromatography SFC)

methods, introduction, calibration of instruments and validation of methods.

Reagents, pharmacopoeia procedures for standardization of reagents and volumetric

solutions.


Cases of quantitative analyses of nonorganic/organic compounds in simple samples,

pharmaceutical and complex biological samples using electrogravimetry, potentiometric

titrations, UV-Vis spectrophotometry, AAS, calorimetric analyses or chromatography.

Comparison and validation of methods. General pharmacopoeia reagents, making,

labeling and storing.


Lectures, practical laboratory work, individual assignments, group discussion methods




teaching,

17

e-teaching


exercises,


work

18


16.2. Individual work hours

16.3. Homework hours




oral)

10 points









prerequisites

The student is responsible to actively monitor all

the activities with which it wins points, which

include participation in the ongoing review of

knowledge to get signature and to obtain

necessary number of points to be able to

takethe final exam.

Criteria for passing:

• The Assessment method is based on the

cumulation of points won: lectures, exercises,

colloquiums and paper work;

• colloquia are independent of each other, i.e.

taking one is not a prerequisite for taking the

other colloquium;

• The final exam is also not dependent on the

midterm, they are not a requirement for passing

the final exam, but the total number of points

scored, which should not be less than 42 points;



arrange additional colloquium, when there is

sufficient number of candidates



instruction




Self-evaluation

22.

Literature

22.1.

Required literature


1. Habibur Rachman Applications of

Analytical

Techniques/Methods of

Drug Analyses

Lap Lambert

Academic

Publishing

2012

2. European

Pharmacopoeia, 6th

Edition,

Council of

Europe,

Strasbourg,

2008

3. Б. Ѓорѓеска Презентации од

предавања и вежби

22.2.



1. Ashutosh Car Pharmaceutical drug

analysis

New Age

International

Ltd.

2005

2. D. G. Watson, Pharmaceutical

analysis, A Textbook

for Pharmacy Students

and Pharmaceutical

Chemists,

Churchill

Livingstone,

Oxford,

1999

3.

first year - i semester 4 0+0+4 120 ugd100112...study program: medical laboratory technicians code...

Documents