ANZOS 2013 abstracts e35

p = 0.4) or PI (2.7 ± 0.0 vs 2.7 ± 0.0, p = 0.53) inthe HE vs LGI groups respectively. The prevalenceof infants who were small or large for gestationalage was similar in both groups (p = 0.81). In multi-variate regression analysis, dietary glycaemic load(GI x carbohydrate content) was the only signif-icant dietary predictor (p = 0.046) of the primaryoutcomes after adjustment for type of delivery(spontaneous, Caesarean or instrumental) and gen-der, but explained less than 1% of the variation.

A low intensity dietary intervention in pregnancywith either a low GI or conventional healthy dietdoes not influence pregnancy outcomes in healthywomen.

http://dx.doi.org/10.1016/j.orcp.2013.12.569

71

Fitness, function, activity andscreen time—–Can benefits from a12 week exercise program bemaintained? The RESIST study

Megan L. Gow 1,2,∗, Nancy vanDoorn 3,4, Mandy Ho 1,2, Carolyn R.Broderick 3,4, Louise A. Baur 2,5, ChrisT. Cowell 1,2,5, Sarah P. Garnett 1,2,5

1 Institute of Endocrinology andDiabetes, The Children’s HospitalWestmead, Westmead, NSW,Australia2 Discipline of Pediatrics and ChildHealth, University of Sydney, Sydney,NSW, Australia3 The Children’s Hospital Institute ofSports Medicine, The Children’sHospital Westmead, Westmead, NSW,Australia4 School of Medical Sciences,University of New South Wales,Sydney, NSW, Australia5 Kids Research Institute, TheChildren’s Hospital Westmead,Westmead, NSW, Australia

Introduction: Adolescent obesity is associatedwith poor fitness and decreased capacity to performfunctional tasks. This study examined the effect ofa structured exercise program as part of a lifestyleintervention on fitness, physical function, physicalactivity and screen time.

Methods: Participants were obese 10—17 yearolds, with insulin resistance participating in a12 month RCT, known as RESIST. The primaryaim of RESIST was to determine the optimaldietary macronutrient content to improve insulin

sensitivity. As part of RESIST, 99 adolescents par-ticipated in two supervised exercise sessions perweek for 12 weeks. Fitness (peak oxygen uptake)and physical function (exercise time and anaerobicthreshold) were measured by gas analysis duringthe Bruce treadmill protocol at baseline, postintervention and at follow up 6 months aftercompletion of the exercise intervention. Physicalactivity and screen time were measured by a vali-dated questionnaire (CLASS) and body compositionby dual energy X-ray absorptiometry.

Results: At baseline peak oxygen uptake(VO2max) was low (estimated marginal mean ±SEM = 23.8 ± 0.5 mL/kg/min), as was exercise timeand anaerobic threshold, however, all improvedpost intervention by 5.8% [95%CI: 0.8—11.3], 8.5%[95%CI: 3.8—13.3] and 19.7% [95%CI: 10.4—29.0],respectively. These improvements were maintainedat follow up. Compared to baseline, post interven-tion physical activity levels increased by 21 min/day[95%CI: 7—35] and screen time decreased by48 min/day [95%CI: 17—78] but had returned tobaseline levels by follow up. Decreased percentagebody fat was associated with increased peak oxygenuptake (r = −0.24, P = 0.032) and increased exercisetime (r = −0.30, P = 0.008).

Conclusions: A structured exercise programcan lead to sustainable improved aerobic fitness,including improved exercise tolerance, facilitat-ing functional task performance. However, fitnesslevels were still low, warranting further inves-tigation into optimal exercise interventions andstrategies to improve physical activity and screentime long-term.

http://dx.doi.org/10.1016/j.orcp.2013.12.570