“Flow Characterization in a Microfluidic Compact Disc (CD) Platform for

Clinical Diagnosis”

SURF-IT Fellow: Bryce Kubo

Mentor: Professor Marc Madou

Kameel Abi-Samra

What is microfluidics?

Fig. 5 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

http://www.ayhanozdemir.net/STEEL%20REINFORCED%20PE%20SPIRAL%20CORRUGATED%20PIPE%20MANUFACTURING%20LINE_files/image007.jpg

What I am testing

Materials: Plastic vs. Silicon Speed of Rotation: Slow vs. Fast Width of the Channels: Wide vs. Narrow Distance from Center: Close vs. Far

ρωc2ṝ∆r = a(4γ/Dh) + b

The angular frequency in which the liquid will break through the capillary valve and begin flowing

Burst Frequency

M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

How can a simple plastic CD be used for biomedical testing?

Mixing Liquids Valving Metering

Valving

Fig. 2 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

Metering

Fig. 4 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

SpinDEP

Fig. 1 from R. Martinez-Duarte, et al, “The Integration of 3D Carbon Dielectrophoresis on a Rotating Platform”

Any Questions?