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1260 UNIVERSITY COLLEGE HOSPITAL.-ICTERUS NEONATORUM. of wind and weather. They will almost certainly be found to have left their mark upon the public health in an unex- pected prevalence of pneumonia, pleurisy, and allied inflammatory ailments. The time-honoured and truly wise injunction with regard to change of clothing during May might this year be transferred with general advantage to our chilly June. Particularly should the elderly and the very young be clad with careful regard for sudden changes in the outer temperature, and if any one point more than another should be emphasised in making such arrangements, it is the great advantage, almost the necessity, of wearing next the skin a layer of woollen material. UNIVERSITY COLLEGE HOSPITAL. LORD HERscHELL presided at the public dinner in aid of the funds of this institution, which took place at the 116tel Métropole on Tuesday last. A large and distinguished com- pany were present His lordship urged the claims of the chaiity upon public benevolence, observing that the number of patients had greatly increased during the past year, and the funds of the hospital were still deficient in relation to its needs. He alluded to a scheme on foot for rebuilding the hospital, and trusted that when that was done they would, with the assistance of the public, have a building befitting the great work the institution was doing for the inhabitants of London. The donations in connexion with I the festival amounted to over .E1900. INTRA-PULMONARY INJECTION OF CREASOTE. DR. T. STACHIEWICZ of Görbersdorf has followed up the attempts to arrest tuberculosis by deep injections of creasote into the substance of the lung, which met with such favourable results in the hands of Dr. Rosenbusch (see THE LANCET, p. 643, March 31st, 1888), but without being able to show nearly such good effects; indeed, in one case fever and haemoptysis came on, and the cough and ex- pectoration increased. Notwithstanding his unpromising results, Dr. Stachiewicz is disposed to think that intra- pulmonary injections of creasote may perhaps be of service where the cavities are superficial, or where there are hydatids or gangrene of the 1-ung, and he suggests that it may perhaps be resorted to in some desperate cases of phthisis merely as a last resort. ICTERUS NEONATORUM. SEVERE icterus neonatorum is usually observed, according to Kehrer, on the second or third day after birth. Baginsky noted the first discolouration on the face and breast, the abdomen, extremities, and eyes being affected later. Frerichs found the weight of the liver in the seven-months’ fcetua to be 1-17th of the weight of the entire body, and in the foetus at term 1-25th; in a child aged sixteen months it was only 1-33rd ; it is larger in the mature fcetus than both the lungs, according to Beneke and Baginsky. The red corpuscles, which number from six to seven millions per cubic centi- metre on the first day of life, are found to number only from four to five millions on the fourth or fifth day. Hofmeier ascertained the size of the red corpuscles to be very variable; that they are more spherical than in the blood of adults; that they show no tendency to form rouleaux ; that the white corpuscles are often in greater proportion than in adult’s blood, and that they accumulate in rouleaux; that they are viscid, deliquescent, and easily destroyed. Ponfick and Silbermann found "shadows" of red blood-corpuscles to be more abundant the greater the disturbance during the first days of life. Silbermann injected haemoglobin into the blood of frogs, dogs, and puppies, and found that the changes in the blood, urine, and liver corresponded with those which are seen in new-born infants during the first days of life. Hofmeier showed that in jaundiced infants during the first ten days of life there was a decided loss of weight and a great increase in the elimination of urea, uric acid infarcts, and albumen. Perls has shown that bile has the power of dissolving the red corpusclefl, of depressing the temperature and cardiac action, and of paralysing the activity of nerve and muscle. Currier in the Archives of Paediatrics, No. 53, draws a clear distinction between cases of icterus due to excess of bcemoglobin in the blood, those which are due to resorption of bile, and those which result from septic elements and conditions. He considers that to speak with Silbermann and Schmidt of any fermentation process occurring in the blood in cases of non-septic icterus is incorrect. ___ TESTIMONIAL TO DR. GEORGE JOHNSON. NUMEROUS friends and former pupils attended with the medical staff at King’s College on June 14th,when,in the name of the subscribers, Sir Joseph Lister presented Dr. George Johnson with the testimonial portrait painted by Mr. Frank HolJ, R.A. Professor Bentley, late Dean of the Medical Department, also presented a handsome volume containing the names of subscribers, and Sir William Bowman spoke briefly on behalf of the College Council. Dr. Johnson, in reply, gave an interesting summary of his career from its commencement. He made graceful allusion to the help and encouragement he had received from Dr. Robert Bentley Todd, and later from Sir Thomas Watson; he also spoke of his work in connexion with kidney disease, and of the discus. sion which was roused by his theory of collapse and his treat- ment of cholera. The portrait at first sight, perhaps, is a little disappointing, but it grows upon those who are familiar with Dr. Johnson’s face in thoughtful repose. ST. THOMAS’S HOSPITAL. THE distribution of prizes to the students of St. Thomas’s Hospital will take place in the Governors’ Hall, on Thursday, July 5th, by Professor George G. Stores, D.C.L., LLD.,D.Sc., M.P., President of the Royal Society. Mr. Nettleship has been appointed Dean of the Medical School, in the place of Dr. Ord, who has so well filled this post for the past ten years, and to whose ability and unsparing energy much of the great success of this school is due. FOREIGN UNIVERSITY INTELLIGENCE. l3erlia. Prof. Ernst Pfitzer, of Heidelberg, is proposed as the new Director of the Botanic Gardens, in succession to Prof. Eichler. Buda Pesth.-Prof. Franz Yarga has been appointed Director of the Veterinary Institute. Greifswald.-Dr. F. Loeffler, staff surgeon and privat docent in the University of Berlin, has been appointed to the Professorship of Hygiene. Jena.--For the Anatomical Chair there were proposed, in addition to Prof. Furbringer of Amsterdam, Profs. Carl Bardleben of Jena and Stohr of Wiirzburg, and also, but with a smaller number of votes, Profs. Born of Breslau, Ruge of Heidelberg, and Roux of Breslau. Vienna.-Prof. J. Hyrtl has given six_scholarships for medical students, open to those of all nations. DEATHS OF EMINENT FOREIGN MEDICAL MEN. THE deaths of the following eminent foreign medical men are announced :-Dr. Karl Kilcher, assistant in the Bohemian Laboratory of Pathological Anatomy, from blood poisoning, contracted during the pursuance of researches on the blood of typhus fever patients.-Dr. Franz Torday, Docent in children’s diseases in Buda Pesth.-Dr. Josef Ossikovszki, Professor of Physiological and Pathological Chemistry in the University of Clausenburg.

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1260 UNIVERSITY COLLEGE HOSPITAL.-ICTERUS NEONATORUM.

of wind and weather. They will almost certainly be foundto have left their mark upon the public health in an unex-pected prevalence of pneumonia, pleurisy, and allied

inflammatory ailments. The time-honoured and truly wiseinjunction with regard to change of clothing during Maymight this year be transferred with general advantage toour chilly June. Particularly should the elderly and thevery young be clad with careful regard for sudden changesin the outer temperature, and if any one point more thananother should be emphasised in making such arrangements,it is the great advantage, almost the necessity, of wearingnext the skin a layer of woollen material.

UNIVERSITY COLLEGE HOSPITAL.

LORD HERscHELL presided at the public dinner in aid ofthe funds of this institution, which took place at the 116telMétropole on Tuesday last. A large and distinguished com-pany were present His lordship urged the claims of thechaiity upon public benevolence, observing that the numberof patients had greatly increased during the past year, andthe funds of the hospital were still deficient in relation toits needs. He alluded to a scheme on foot for rebuildingthe hospital, and trusted that when that was done theywould, with the assistance of the public, have a buildingbefitting the great work the institution was doing for theinhabitants of London. The donations in connexion with Ithe festival amounted to over .E1900.

INTRA-PULMONARY INJECTION OF CREASOTE.

DR. T. STACHIEWICZ of Görbersdorf has followed up the

attempts to arrest tuberculosis by deep injections ofcreasote into the substance of the lung, which met withsuch favourable results in the hands of Dr. Rosenbusch (seeTHE LANCET, p. 643, March 31st, 1888), but without beingable to show nearly such good effects; indeed, in one casefever and haemoptysis came on, and the cough and ex-pectoration increased. Notwithstanding his unpromisingresults, Dr. Stachiewicz is disposed to think that intra-pulmonary injections of creasote may perhaps be of servicewhere the cavities are superficial, or where there are

hydatids or gangrene of the 1-ung, and he suggests thatit may perhaps be resorted to in some desperate cases ofphthisis merely as a last resort.

ICTERUS NEONATORUM.

SEVERE icterus neonatorum is usually observed, accordingto Kehrer, on the second or third day after birth. Baginskynoted the first discolouration on the face and breast, theabdomen, extremities, and eyes being affected later. Frerichsfound the weight of the liver in the seven-months’ fcetua tobe 1-17th of the weight of the entire body, and in the foetusat term 1-25th; in a child aged sixteen months it was only1-33rd ; it is larger in the mature fcetus than both the lungs,according to Beneke and Baginsky. The red corpuscles,which number from six to seven millions per cubic centi-metre on the first day of life, are found to number only fromfour to five millions on the fourth or fifth day. Hofmeierascertained the size of the red corpuscles to be very variable;that they are more spherical than in the blood of adults;that they show no tendency to form rouleaux ; that thewhite corpuscles are often in greater proportion than inadult’s blood, and that they accumulate in rouleaux; thatthey are viscid, deliquescent, and easily destroyed. Ponfickand Silbermann found "shadows" of red blood-corpusclesto be more abundant the greater the disturbance during thefirst days of life. Silbermann injected haemoglobin into theblood of frogs, dogs, and puppies, and found that the changesin the blood, urine, and liver corresponded with those whichare seen in new-born infants during the first days of life.

Hofmeier showed that in jaundiced infants during thefirst ten days of life there was a decided loss of weight anda great increase in the elimination of urea, uric acid infarcts,and albumen. Perls has shown that bile has the power of

dissolving the red corpusclefl, of depressing the temperatureand cardiac action, and of paralysing the activity of nerveand muscle. Currier in the Archives of Paediatrics, No. 53,draws a clear distinction between cases of icterus due toexcess of bcemoglobin in the blood, those which are due toresorption of bile, and those which result from septicelements and conditions. He considers that to speak withSilbermann and Schmidt of any fermentation processoccurring in the blood in cases of non-septic icterus isincorrect.

___

TESTIMONIAL TO DR. GEORGE JOHNSON.

NUMEROUS friends and former pupils attended with themedical staff at King’s College on June 14th,when,in the nameof the subscribers, Sir Joseph Lister presented Dr. GeorgeJohnson with the testimonial portrait painted by Mr. FrankHolJ, R.A. Professor Bentley, late Dean of the Medical

Department, also presented a handsome volume containingthe names of subscribers, and Sir William Bowman spokebriefly on behalf of the College Council. Dr. Johnson, inreply, gave an interesting summary of his career from itscommencement. He made graceful allusion to the help andencouragement he had received from Dr. Robert BentleyTodd, and later from Sir Thomas Watson; he also spoke ofhis work in connexion with kidney disease, and of the discus.sion which was roused by his theory of collapse and his treat-ment of cholera. The portrait at first sight, perhaps, is alittle disappointing, but it grows upon those who are

familiar with Dr. Johnson’s face in thoughtful repose.

ST. THOMAS’S HOSPITAL.

THE distribution of prizes to the students of St. Thomas’sHospital will take place in the Governors’ Hall, on Thursday,July 5th, by Professor George G. Stores, D.C.L., LLD.,D.Sc.,M.P., President of the Royal Society. Mr. Nettleship hasbeen appointed Dean of the Medical School, in the place ofDr. Ord, who has so well filled this post for the past tenyears, and to whose ability and unsparing energy much ofthe great success of this school is due.

FOREIGN UNIVERSITY INTELLIGENCE.

l3erlia. Prof. Ernst Pfitzer, of Heidelberg, is proposed asthe new Director of the Botanic Gardens, in succession toProf. Eichler.Buda Pesth.-Prof. Franz Yarga has been appointed

Director of the Veterinary Institute.Greifswald.-Dr. F. Loeffler, staff surgeon and privat

docent in the University of Berlin, has been appointed to theProfessorship of Hygiene.Jena.--For the Anatomical Chair there were proposed, in

addition to Prof. Furbringer of Amsterdam, Profs. CarlBardleben of Jena and Stohr of Wiirzburg, and also, butwith a smaller number of votes, Profs. Born of Breslau, Rugeof Heidelberg, and Roux of Breslau.

Vienna.-Prof. J. Hyrtl has given six_scholarships formedical students, open to those of all nations.

DEATHS OF EMINENT FOREIGN MEDICAL MEN.

THE deaths of the following eminent foreign medical menare announced :-Dr. Karl Kilcher, assistant in the BohemianLaboratory of Pathological Anatomy, from blood poisoning,contracted during the pursuance of researches on the bloodof typhus fever patients.-Dr. Franz Torday, Docent inchildren’s diseases in Buda Pesth.-Dr. Josef Ossikovszki,Professor of Physiological and Pathological Chemistry inthe University of Clausenburg.