fsa 28 feb 2003 - landlaeknir.is · sykursýki af tegund tvö 832 lÆknablaÐiÐ2002/88...

empty Sigurethur HelgasonRitstjoacuteri Kliacuteniacuteskraleiethbeininga

Kliacuteniacuteskar leiethbeiningar

Forsiacuteetha Gaeligethi ogeftirlit

Stofnanir og starfsfoacutelk iacuteheilbrigethisthornjoacutenustu

Lyacuteethheilsa Soacutettvarnir Heilbrigethistoumllfraeligethi Kvartanir og

kaeligrur


Landlaeligknisembaeligttieth

Uacutetgaacutefa

Skraacutening iacuteheilbrigethisthornjoacutenustu


--Bakverkir--Barnaastmi--Beinthornynning af

voumlldum sykurstera--Endurliacutefgun - nyacutett--Hjarta- og

aeligethasjuacutekdoacutemar--Huacuteethfluacuterhuacuteethgoumltun--Houmlfuethaacuteverkar--Klamyacutediacutea--Langvinn lungnateppa

- nyacutett--Lifrarboacutelga C--MS--Neyethargetnaetharvoumlrn--Ofnaeligmislost--Ristilkrabbamein--Sykursyacuteki af tegund 2--Um kliacuteniacuteskar

leiethbeiningar--Aethrir vefir--Fraeligethslufundir--Leiethbeiningar iacute

vinnslu

Loumlg og reglugerethir

Eyethubloumleth

Aethrir vefir

English


Kliacuteniskar leiethbeiningar

SkilgreiningKliacuteniacuteskar leiethbeiningar (clinical guidelines) eru kerfisbundnar leiethbeiningar (ekki fyrirmaeligli) um aacutekvarethanir sem luacuteta aethkliacuteniacuteskum vandamaacutelum iacute laeligknisfraeligethi THORNaeligr taka mieth af bestu thornekkingu aacute hverjum tiacutema og eru lagethar fram iacute thornviacute skyni aethveita sem besta meethfereth meeth sem minnstri aacutehaeligttu aacuten oacutehoacuteflegs kostnaethar meira

Erlendar stofnanir semgefa uacutet kliacuteniacuteskar

leiethbeiningar

Scottish IntercollegiateGuideline Network

NICE

New Zealand GuidelinesGroup

Naacutenar um gereth kliacuteniskra leiethbeininga

Styacuterihoacutepur Stuethningsaethilar

Vinnuhoacutepar Vinnulag vieth gereth kliacuteniacuteskar leiethbeininga

Stigun raacuteethlegginga

Kliacuteniacuteskar leiethbeiningarsem nuacute eru iacute vinnslu

Influacuteensa - lyfjameethfereth

Offita barna Greining og meethfereth

Eyrnaboacutelga Greining og meethfereth

Uppfaeligrt 25 apriacutel 2003

Sjaacute einnig Stuethningsaethilar Prentvaelign uacutetgaacutefa

Landlaeligknisembaeligttieth Austurstroumlnd 5 170 Seltjarnarnes siacutemi 510 1900 fax 510 1919 toumllvupoacutestur posturlandlaekniris




kaeligrur

Kliacuteniacuteskar leiethbeiningar Um kliacuteniacuteskar leiethbeiningar Vinnuhoacutepar

Vinnuhoacutepar

Vinnuhoacutepar vieth gereth kliacuteniacuteskra leiethbeininga

Aacutehaeligttumat kransaeligethasjuacutekdoacutema (Leiethbeiningar uacutetgefnar 2001)Gunnar Toacutemasson laeligknirSigurethur Helgason laeligknir Bakverkur (Leiethbeiningar uacutetgefnar iacute desember 2002)Magnuacutes Oacutelason laeligknirGiacutesli THORN Juacuteliacuteusson laeligknirRagnar Joacutensson laeligknirSigurethur Helgason laeligknir Barnaastmi (Leiethbeiningar uacutetgefnar iacute maiacute 2002)Bjoumlrn Aacuterdal laeligknirGunnar Joacutenasson laeligknirIngoacutelfur Kristjaacutensson laeligknirRannveig Einarsdoacutettir lyfjafraeligethingurSigurethur Helgason laeligknir (formaethur)Sigurethur Kristjaacutensson laeligknir Beinthornynning (iacute vinnslu)Aethalsteinn Guethmundsson laeligknir (formaethur)Ari Joacutehannesson laeligknirBjoumlrn Guethbjoumlrnsson laeligknirRannveig Einarsdoacutettir lyfjafraeligethingurSigriacuteethur Bjoumlrnsdoacutettir laeligknirSigurethur Helgason laeligknir Beinthornynning af voumlldum sykurstera (Leiethbeiningar uacutetgefnar iacute februacutear 2002)Aethalsteinn Guethmundsson laeligknirBjoumlrn Guethbjoumlrnsson laeligknir (formaethur)Rannveig Einarsdoacutettir lyfjafraeligethingurSigurethur Helgason laeligknir Braacuteethir kransaeligethasjuacutekdoacutemar (Leiethbeiningar uacutetgefnar iacute mars 2002)Daviacuteeth O Arnar laeligknirRagnar Daniacuteelssen laeligknir

Braacuteethur niethurgangur hjaacute boumlrnum (iacute vinnslu)Luacutether Sigurethsson laeligknirUacutelfur Agnarsson laeligknir

BuprenorphineErla Axelsdoacutettir laeligknirGuethbjoumlrn Bjoumlrnsson laeligknirMatthiacuteas Halldoacutersson laeligknirTHORNoacuterarinn Tyrfingsson laeligknirTHORNoacuterethur G Oacutelafsson laeligknir

Endurliacutefgun seacuterhaeligfeth (Leiethbeiningar uacutetgefnar iacute mars 2003)Daviacuteeth O Arnar laeligknirHjalti Maacuter Bjoumlrnsson laeligknir

Faglegir umsagnaraethilarAri Joacutehannesson laeligknirFelix Valsson laeligknirHrafnkell Oacuteskarsson laeligknirLaacuterus Petersen Landssambandi Sloumlkkvilieths og sjuacutekraflutningamannaRagnar Danielsen laeligknirTHORNoacuterir B Kolbeinsson laeligknir

--Hjarta- ogaeligethasjuacutekdoacutemar

--Huacuteethfluacuterhuacuteethgoumltun--Houmlfuethaacuteverkar--Klamyacutediacutea--Langvinn lungnateppa


leiethbeiningar--- Vinnuhoacutepar--- Vinnulag--- Stigun raacuteethlegginga--- Stuethningsaethilar--- Styacuterihoacutepur

--Aethrir vefir--Fraeligethslufundir--Leiethbeiningar iacute

vinnslu


Eyethubloumleth

Aethrir vefir

English

Rannveig Einarsdoacutettir lyfjafraeligethingurSigurethur Helgason laeligknir Hoacutepur stofnaethur iacute oktoacuteber 2002Huacuteethfluacuterun og goumltun (Leiethbeiningar uacutetgefnar iacute september 2000)Aacuternyacute Sigurethardoacutettir hjuacutekrunarfraeligethingurAacutesa Atladoacutettir hjuacutekrunarfraeligethingurMatthiacuteas Halldoacutersson laeligknirSigurethur Helgason laeligknir (formaethur)

Houmlfuethaacuteverkar (Leiethbeiningar uacutetgefnar iacute noacutevember 2001)Kristinn R Guethmundsson laeligknir (formaethur)Bjarni Hannesson laeligknirGunnar Toacutemasson laeligknirSigurethur Helgason laeligknirTHORNorbergur Houmlgnason laeligknir

Influacuteensa (iacute vinnslu)Gunnar Gunnarsson laeligknirGunnar Toacutemasson laeligknirMagnuacutes Gottfreethsson laeligknir (formaethur)

Kinnholuboacutelga hjaacute boumlrnum (iacute vinnslu)Friethrik Guethbrandsson laeligknirKarl G Kristinsson laeligknirVilhjaacutelmur A Arason laeligknir (formaethur)THORNoacuteroacutelfur Guethnason laeligknir

Klamyacutediacutea ( Leiethbeiningar uacutetgefnar iacute februacutear 2001)Joacuten Hjaltaliacuten Oacutelafsson laeligknirOacutelafur Steingriacutemsson laeligknirRannveig Einarsdoacutettir lyfjafraeligethingurReynir Toacutemas Geirsson laeligknirSigurethur Helgason laeligknirSteingriacutemur Daviacuteethsson laeligknir (formaethur)

Langvinnir lungnateppusjuacutekdoacutemar (Leiethbeiningar uacutetgefnar iacute mars 2003)Gunnar Guethmundsson laeligknirHalldoacuter Joacutensson laeligknirJoacuten Bjarnarson laeligknirSigurethur Helgason laeligknirTHORNoacuterarinn Giacuteslason laeligknir (formaethur)

Mjaethmarbrot forvarnir og meethfereth (iacute vinnslu)Aethalsteinn Guethmundsson laeligknirFriethrik V Guethjoacutensson laeligknirHalldoacuter Joacutensson laeligknirJoacuten Ingvar Ragnarsson laeligknirOacuteloumlf R Aacutemundadoacutettir sjuacutekrathornjaacutelfiSigurethur Helgason laeligknirYngvi Oacutelafsson laeligknirTHORNorvaldur Ingvarsson laeligknir (formaethur)

Faglegir raacuteethgjafarGirish HirlekarOacutelafur R IngimarssonPaacutell Torfi OumlnundarsonPeacutetur HannessonSigurethur B THORNorsteinsson

Myndgreining (Leiethbeiningar uacutetgefnar iacute september 2000)Aacutesmundur Brekkan laeligknir (formaethur)Baldur F Sigfuacutesson laeligknirEythornoacuter Bjoumlrgvinsson laeligknirHalldoacuter Benediktsson laeligknirHaukur Valdimarsson laeligknirKolbruacuten Benediktsdoacutettir laeligknirOacutelafur Kjartansson laeligknirSigurethur Helgason laeligknir

Endurskoethun iacute mars 2003Anna Bjoumlrg Halldoacutersdoacutettir roumlntgenlaeligknirGuethlaugur Einarsson geislafraeligethingurGuethmundur Joacuten Eliacuteasson roumlntgenlaeligknirHalldoacuter Benediktsson roumlntgenlaeligknirIethunn Leifsdoacutettir roumlntgenlaeligknirJoumlrgen Albrechtsen roumlntgenlaeligknirKolbruacuten Benediktsdoacutettir roumlntgenlaeligknir (formaethur)Kristbjoumlrn Reynisson roumlntgenlaeligknirPeacutetur Hannesson roumlntgenlaeligknir

Neyethargetnaetharvoumlrn (Leiethbeiningar uacutetgefnar iacute mars 2001 endursk noacutevember 2002 og mars 2003)Anna Bjoumlrg Aradoacutettir hjuacutekrunarfraeligethingurHjoumlrdiacutes Harethardoacutettir laeligknir

LaeligknablaethiethHliacuteethasmaacutera 8 - 201 KoacutepavogiSiacutemi 564 4104 - Fax 564 4106

2 tbl 88 aacuterg 2002

Houmlfundar

AethalsteinnGuethmundsson12Sigurethur Helgason23Bjoumlrn Guethbjoumlrnsson4

Yfirlit

InngangurEnglish SummaryMeingerethSkilgreiningarMeethferethBisfosfoacutenoumltOumlstroacutegenRaloxifen og tiacuteboacuteloacutenTestoacutesteroacutenKalsiacutetoacuteniacutenTiacuteaziacuteeth thornvagraeligsilyfNyacutejar meethferetharleiethirSamantektHeimildir

Lykiloreth

sykursterar beinthorneacutettnibeinthornynningbisfosfoacutenoumlt D-viacutetamiacutenkalk karlhormoacutenkvenhormoacuten

Almennt

1Oumlldrunarsvieth2Landspiacutetali - Hrafnistu3Landlaeligknisembaeligttieth4Rannsoacuteknarstofa iacutegigtsjuacutekdoacutemumFyrirspurnir BjoumlrnGuethbjoumlrnsson netfangbjorngulandspitaliisGrein thornessi er afraksturstarfshoacuteps um kliacuteniacuteskarleiethbeiningar aacute vegum

Fraeligethigreinar

Forvarnir og meethferethbeinthornynningar af voumlldumsykurstera KliacuteniacuteskarleiethbeiningarBeinthornynning er algeng og alvarleg hjaacuteverkun langtiacutemameethferethar meethsykursterum Meeth virkri forvoumlrn ogeetha seacutertaeligkri meethfereth gegnbeinthornynningu er unnt aeth draga uacuter thorneim heilsufarsvanda ogsamfeacutelagskostnaethi sem hlyacutest af beinthornynningu af voumlldumsykursterameethferethar Leiethbeiningar thornessar eru settar fram samkvaeligmt goacuteethriog skynsamlegri aacutekvarethanatoumlku (evidence based) og eru aeligtlaethar laeligknumsem bera aacutebyrgeth aacute meethfereth sjuacuteklinga aacute langtiacutema sykursterameethfereth Iacutedaglegu starfi getur verieth erfitt aeth fylgja thornessum leiethbeiningum til daeligmiseru beinthorneacutettnimaeliglingar eingoumlngu framkvaeligmdar iacute Reykjaviacutek og aacute Akureyri

Inngangur

Sykursterar eru algeng meethfereth vieth moumlrgum boacutelgu- ogbandvefssjuacutekdoacutemum og thorneir eru einnig notaethir til oacutenaeligmisbaeliglingar tildaeligmis eftir liacuteffaeligraiacutegraeligethslur Samkvaeligmt nyacutelegri iacuteslenskri rannsoacutekn maacutegera raacuteeth fyrir thornviacute aeth ruacutemlega 2000 einstaklingar seacuteu aacute samfelldrisykursterameethfereth heacuter aacute landi aacute hverjum tiacutema Helstu aacutebendingar erulangvinnir gigtarsjuacutekdoacutemar (43) lungnasjuacutekdoacutemar (33) eethaboacutelgusjuacutekdoacutemar iacute goumlrn (8) (1)

Sykursterar eru algengasti lyfjaflokkurinn sem orsakar beinthornynningu aethminnsta kosti meethal yngra foacutelks (2) Afleiethingar beinthornynningar aacute heilsufarog liacutefsgaeligethi einstaklinga sem nota sykurstera eru umtalsverethar Fimmtaacutenproacutesent thorneirra sem faacute langtiacutemameethfereth meeth sykursterum veretha fyrirsamfallsbroti iacute hrygg aacute fyrsta meethferetharaacuterinu og thornriethjungur beinbrotnar aacutefyrstu fimm aacuterum meethferethar (3) THORNoacutett ekki seacute aeth fullu ljoacutest hvernigsykursterar valda beinthornynningu er um aeth raeligetha samverkan af haeliggaribeinnyacutemyndun og aukinni beineyethingu meethan aacute meethfereth stendur (4)

Langflestir thorneirra sem nota sykurstera til lengri tiacutema tapa umtalsverethribeinthorneacutettni sem siacuteethan veldur aukinni haeligttu aacute beinbrotum Beintap thornetta erhlutfallslega hraethast fyrstu meethferetharmaacutenuethina Faraldsfraeligethilegarrannsoacuteknir hafa syacutent aeth haeligtta aacute beinbrotum thornaacute seacuterstaklega iacute hrygg ogmjoumlethm eykst iacute reacutettu hlutfalli vieth skammtastaeligreth og tiacutemalengdmeethferetharinnar (5)

Kannanir heacuterlendis og erlendis hafa syacutent aeth mjoumlg stoacuter hluti thorneirra sjuacuteklingasem nota sykurstera faeligr oacutefullnaeliggjandi forvoumlrn gegn beinthornynningu (1 6-8)THORNessar rannsoacuteknir syacutena aeth einstaklingar sem hafa thornekkta beinthornynningu(jafnvel meeth beinbrotum) iacute upphafi sykursterameethferethar njoacuteta ekki thorneirrarmeethferethar sem voumll er aacute iacute dag Aacute undanfoumlrnum aacuterum hafa opnast nyacuteirmoumlguleikar til greiningar beinthornynningu og ekki siacuteethur varethandi forvoumlrn og

Tafla I

Tafla II

Tafla III

Tafla IV

Tafla V

Sykursyacuteki af tegund tvouml

832 LAElig K NAB LAETHI ETH 200288

Taeligkifaeligrisskimun aacutehaeligttuhoacutepa aacute eins til thornriggja aacutera fresti

Iacute aacutehaeligttuhoacutepi eru thorneir sem

hafa haacutethornryacutesting hjarta- eetha aeligethasjuacutekdoacutem eru ekki af evroacutepskum uppruna

eru of feitir eru 20 eetha meira yfir kjoumlrthornyngd hafa skert sykurthornol (IGT ndash impaired glucose= thornyngdarstuethull (BMI ndash body mass index) ge27 tolerance) eetha haeligkkaethan foumlstu bloacuteethsykur

(IFG ndash impaired fasting glucose) hafa haeligkkaethar bloacuteethfitur seacuterstaklega TG

og laacutegt HDL hafa fengieth sykursyacuteki aacute meethgoumlngu

eiga foreldra eetha systkin meeth sykursyacuteki eru 45 aacutera eetha eldri

TG triglyceridethornriacuteglyacuteseriacuteeth HDL high densityhaacutethorneacutettni liacutepoacuteproacutetiacuten

Taeligkifaeligrisskimun meeth fastandi sykri iacute heilbloacuteethi (iacute sermi)

Ekki sykursyacuteki lt 56 (65) ge 56 (65)

Endurtaka

lt 56 (61) 56-60 (61-69) 2 gildi ge 61 (70)

Sykursyacuteki

Haeligkkaethur foumlstu bloacuteethsykur (hugleietha sykurthornolsproacutef)

Meethhoumlndlunarmarkmieth og tiacuteethni eftirlits

Maeliglistaeligreth Tiacuteethni Viethmiethunarmoumlrk

HbA1c Aacute thornriggja til toacutelf maacutenaetha fresti lt 70

Liacutekamsthornyngd Vieth hverja komu til laeligknis

Liacutekamsthornyngdarstuethull BMI Einstaklingsbundieth(Karlar 20-25)(Konur 19-24)

Bloacuteeththornryacutestingur Vieth hverja komu til laeligknis lt 14080

Heildarkoacutelesteroacutel Aacuterlega lt 50 mmoacutellHDL-koacutelesteroacutel Aacuterlega gt 12 mmoacutellLDL-koacutelesteroacutel Aacuterlega lt 30 mmoacutellTHORNriacuteglyacuteseriacuteeth Aacuterlega lt 17 mmoacutell

Sykraethur bloacuteethrauethi HDL high densityhaacutethorneacutettni liacutepoacuteproacutetiacuten LDL low densitylaacutegthorneacutettni liacutepoacuteproacutetiacuten

Starfshoacutepur aacute vegum Land-

laeligknisembaeligttis hefur unnieth

aeth gereth kliacuteniacuteskra leiethbeininga

um greiningu og meethfereth

sykursyacuteki af tegund tvouml Iacute

hoacutepnum eru Aacutestraacuteethur B

Hreietharsson Houmlrethur Bjoumlrns-

son (formaethur) Rafn Bene-

diktsson Ragnar Gunnarsson

Rannveig Einarsdoacutettir og

Oacutefeigur THORNorgeirsson

Hoacutepurinn lauk vinnu iacute juacuteniacute

2002 og thornaacute birtust leiethbein-

ingarnar aacute vef Landlaeligknis

Vieth vinnuna var einkum

stuethst vieth nyacutelegar nyacutesjaacutelensk-

ar leiethbeiningar um efnieth thornar

sem thornaeligr thornoacutettu aethgengi-

legastar og byggethar aacute

gagnreyndri laeligknisfraeligethi eins

og sjaacute maacute aacute sloacuteethinni

wwwnzggorgnz

librarycfm

F R AElig ETH I G R E I N A R K L Iacute N Iacute S K A R L E I ETH B E I N I N G A R F R Aacute L A N D L AElig K N I S E M B AElig T T I N U


Toumllur iacute sviga eiga vieth maeliglingar iacute sermi

Kliacuteniacuteskar leiethbeiningar um myndgreiningu

Iacuteslenskar leiethbeiningar um myndgreiningu hafa verieth gefnar uacutet og eru nuacute aethgengilegar aacuteupplyacutesingavef LSH THORNaeligr eru einkum byggethar aacute breskum leiethbeiningum sem voru gefnar uacutet 1998 afUK Royal College of Radiologists og evroacutepskum leiethbeiningum fraacute aacuterinu 2000 EuropeanCommission Referral Guidelines for Imaging en thornaeligr byggja aacute grunni hinna breskuEvroacutepuleiethbeiningarnar hafa verieth thornyacuteddar aacute fjoumllmoumlrg tungumaacutel thorn aacute m finnsku doumlnsku og saelignskuVoru thornaeligr hafethar aeth leietharljoacutesi vieth gereth iacuteslensku leiethbeininganna en innihald thorneirra thornoacute lagaeth aethiacuteslenskum aethstaeligethum

Markmieth leiethbeininganna er aeth leiethbeina um val aacute rannsoacuteknum og veita upplyacutesingar umgeislaskammta og kostnaeth vieth myndgreiningarannsoacuteknir iacute von um aeth hvort tveggja skili seacuter iacutemarkvissri notkun myndgreiningarthornjoacutenustu

Leiethbeiningarnar eru birtar vieth houmlndina aacute heimasiacuteethu myndgreiningarthornjoacutenustu aacute upplyacutesingavef LSHog undir Nyacuteir vefir aacute forsiacuteethu vefsins

Leiethbeiningarnar eru unnar iacute samvinnu Landspiacutetala - haacuteskoacutelasjuacutekrahuacutessLandlaeligknisembaeligttisins og Feacutelags iacuteslenskra roumlntgenlaeligkna

Landlaeligknisembaeligttieth Landspiacutetali - haacuteskoacutelasjuacutekrahuacutes Feacutelag iacuteslenskra roumlntgenlaeligkna

Vinnuferlar um seacuter-haeligfetha endurliacutefgun erubyggethir aacute althornjoacuteethlegumleiethbeiningum iacute endur-liacutefgun sem gefnar voru

uacutet aacuterieth 2000 (Inter-national Guidelines2000 on Cardiopul-

monary Resuscitationand Emergency

Cardiovascular Care)Ferlarnir voru thornyacuteddir ogstaethfaeligrethir af Hjalta MaacuteBjoumlrnssyni og Daviacuteeth O

Arnar og hafa veriethstaethfestir af

EndurliacutefgunarraacuteethiFeacutelagi slysa- og braacuteetha-

laeligkna Feacutelagi hjarta-laeligkna Feacutelagi heimilis-laeligkna og Feacutelagi svaeligf-

ingar- og gjoumlrgaeligslu-laeligkna

128 LAElig K N AB LAETHI ETH 200389


Vinnuferlar fyrir endurliacutefgunVinnuferlar fyrir endurliacutefgun

Fyrra ABCDAacutehersla Aeth veita grunnendurliacutefgun og gefa rafstueth

bull Staethfesta meethvitundarleysibull Raeligsa neyetharteymibull Saeligkja rafstuethtaeligkiOpna (Airway) Opna oumlndunarveg lyfta undir houmlkuBlaacutesa (Breathing) Blaacutesa lofti iacute sjuacutekling meeth maska og belg eetha blaacutestursgriacutemuHnoetha (Circulation) Hefja hjartahnoeth nema merki um bloacuteethflaeligethi seacuteu til staetharStuetha (Defibrillation) Meta takt og stuetha VFpuacutelslausan VT allt aeth thornrisvar iacute roumleth ef thornarf

(Einfasa stuethtaeligki 200 J 300 J 360 J Tviacutefasa stuethtaeligki 150 J 200 J 200 J)

Taktur eftir fyrstu thornrjuacute stueth

Viethvarandi eethaendurtekieth VFVT

Athuga liacutefsmoumlrkFrekari lyfjameethferethDraga bloacuteethprufur

(K+ Ca2 Mg2+ hjartaensiacutem)Hjartaliacutenurit

Seinna ABCDAacutehersla Naacutekvaeligmari greining og meethfereth

(Minnisregla ndash thornarf ekki aeth framkvaeligma iacute thornessari roumleth)

Airway Barkathornraeligetha eins fljoacutett og haeliggt er og setja loft iacute belgBreathing Staethfesta legu aacute barkarennu meeth skoethun og taeligkiBreathing Tryggja barkarennu helst meeth seacutertilgerethri festinguBreathing Staethfesta suacuterefnismettun og loftskiptiCirculation IV naacutel (aeligethaleggur)Circulation Greina takt ndash hjartarafsjaacuteCirculation Gefa lyf iacute samraeligmi vieth takt og aacutestand sjuacuteklingsDifferential diagnosis Mismunagreiningar leita aeth undirliggjandi orsoumlk og meethhoumlndla ef haeliggt er

Adrenaliacuten 1 mg IV gusa endurtekin aacute thornriggja til fimm miacutenuacutetna frestieetha

Vasoacutepressiacuten 40 U IV gusa (tvaeligr lykjur) Einn skammtur einu sinni

Stuetha ef takttruflun er enn til staethar1 x 360 J (eetha tviacutefasa 200 J) innan 30-60 sekuacutendna

Reyna aftur aeth stuetha ef takttruflun er enn til staethar30-60 sekuacutendum eftir hverja lyfjagjoumlf

Iacutehuga hjartslaacutettartruflanalyfAmiacuteoacutedaroacuten 300 mg IV Liacutedoacutekaiacuten 075 mgkg IV

Magnesiacuteum 1-2 g IV aacute tveimur miacutenuacutetum Iacutehuga basagjoumlf

Sleglatif og sleglahraethtaktur aacuten merkja um bloacuteethflaeligethi(VF1puacutelslaus VT2)

Jaacute

Nei

1 VF = Ventricular Fibrillation2 VT = Ventricular Tachycardia

Nota Vasoacutepressiacuten frekar efhjartastopp er talieth af voumlld-um bloacuteeththornurrethar iacute hjarta Ef

Vasoacutepressiacuten er notaeth maacutegefa Adrenaliacuten 1 mg aacute

thornriggja til fimm miacutenuacutetnafresti 10-15 miacutenuacutetum siacuteethar

Amiacuteoacutedaroacuten maacute gefa 300 mgiacute gusu Siacuteethan maacute endurtaka

150 mg gusur ef enn VFpuacutelslaus VT haacutemarks-

skammtur 24 g aacute 24klukkustundum

Gefa Magnesiacuteum ef thornekkthypomagnesemiacutea eetha

hraethtaktur meeth gleiethumQRS-bylgjum

Biacutekarboacutenat maacute gefa efum er aeth raeligetha thornekkta

hyperkalemiacuteu efnaskipta-syacuteringu eetha eitrun af voumlld-

um thornriacutehringlaga geeth-deyfetharlyfja

Unnur Steina BjoumlrnsdoacutettirSigurveig THORN Sigurethardoacutett-ir og Bjoumlrn Ruacutenar Luacuteethviacuteks-son skipuethu vinnuhoacutep um

leiethbeiningar um ofnaeligmis-lost THORNaeligr hafa verieth unnar

iacute samvinnu vieth SigurethHelgason ritstjoacutera kliacuten-

iacuteskra leiethbeininga ogRannveigu Einarsdoacutettur

yfirlyfjafraeligething LSH Leieth-beiningarnar hafa verieth

samthornykktar af Feacutelagi iacutes-lenskra ofnaeligmis- og

oacutenaeligmislaeligkna og verethaendurskoethaethar iacute ljoacutesi

nyacuterrar vitneskju en eigisiacuteethar en eftir tvouml aacuter



Grunur um ofnaeligmislostUrticaria (ofsaklaacuteethi)

Angioedema (ofsabjuacutegur)Hvaeligsandi oumlndun

Liacutefshaeligttuleg einkenniPuacutels BloacuteeththornryacutestingurMerki um suacuterefnisskort

MismunagreiningarOacutevenjuleg sjuacutekdoacutemsmynd

Endurmat

MeethferetharmoumlguleikarAdrenaliacuten IMAntihistamiacutenBarksterar

Fjarlaeliggja ofnaeligmisvald

Kalla eftir aethstoeth (112 neyetharhnappur)Adrenaliacuten Fullorethnir 03-05 mg IM (11000 03-05 ml)

Boumlrn 001 mgkg IM (haacutemark 03-05 mg)Antihistamiacuten Fullorethnir Diacutefenhyacutedramiacuten 50-75 mg IV aacute 5-10 miacutenuacutetum IM eetha PO

Boumlrn 1 mgkg IV eetha PO (haacutemark 75 mg)Fjarlaeliggja ofnaeligmisvald

Ef sjuacuteklingur svarar ekki meethfereth skal hefjaENDURLIacuteFGUN O2 iacute nefgriacutemu halda suacuterefnismettun iacute bloacuteethi gt 90

Hroumleth voumlkvun (09 NaCl Ringerslausn eetha kvoethulausn)BarksterarBloacuteeththornryacutestingshaeligkkandi innrennslislyf (Vasopressors)Berkjuviacutekkandi innoumlndunarlyf

Fullorethnir Ventoliacuten 2 mgml 25 ml gefnir iacute frietharpiacutepu meeth O2

Boumlrn Ventoliacuten 01 mgkg gefnir iacute frietharpiacutepu meeth O2 (haacutemark 5 mg)

BarkathornraeligethingBarkaaacutestunga (varhugavereth lt 10 aacutera)

EndurmatNaacutekvaeligm saga ndash orsakaleit (lyf faeligetha umhverfi athafnir)Voumlktun eftir ofnaeligmislost

Vaeligg ndash miethlungs (ofsaklaacuteethi berkjukrampi) 12 klukkustundirAlvarleg (breyting aacute liacutefsmoumlrkum viethvarandi berkjukrampi) gt 24 klukkustundir

Kennsla ndash raacuteethleggingarEpiPen sprautaMedic Alert merki

NEI

NEI

JAacute

JAacute

IV ndash intravenous = iacute aeligeth IM ndash intramuscular = iacute voumlethva PO ndash per os = um munn

Ofnaeligmislost (anaphylaxis)Ofnaeligmislost (anaphylaxis)

Meethfereth ndash flaeligethirit

Ef grunur er um ofnaeligmislost aacute aeth gefa adrenaliacuten iacute voumlethva (03 til 05 mg eetha 03 til 05 ml af 11000 lausn) og fjarlaeliggja ofnaeligmisvald strax

LAElig K NAB LAETHI ETH 200288 921




Ofnaeligmislost ndash Notkun og skammtastaeligrethir lyfja

FullorethnirI Adrenaliacuten 03-05 mg Ef gefieth er iacute voumlethva thornaacute skal nota iacute thornynningunni 11000 en 110000 thornynnt iacute 5

ml af 09 NaCl ef gefieth er IV eetha iacute barkasloumlngu Endurtaka aacute 10-15 miacutenuacutetna fresti thornar til svoumlrunnaeligst Reacutett er aeth byrja meeth laeliggri skammta hjaacute oumlldruethum eetha hjartasjuacuteklingum (02-04 mg)

II AntihistamiacutenA H1-hemjarar

ndash Difenhyacutedramiacuten 25-75 mg IV aacute 5-10 miacutenuacutetum IM eetha PO maacute endurtaka aacute sex klukkustunda fresti

ndash Clemastinum (Tavegylreg) 1-3 mg PO maacute endurtaka aacute 12 klukkustunda fresti

B H2-hemjararndash Ranitidin 300 mg PO aacute soacutelarhring eetha 50 mg IV aacute aacutetta klukkustunda frestindash Cimetidine 300 mg PO

III BarksterarA Prednisoacuteloacuten 05-1 mgkgsoacutelarhring iacute tveimur til thornremur joumlfnum skoumlmmtum PO

B Metyacutelprednisoacuteloacuten (Solu-Medrolreg) 1-2 mgkgsoacutelarhring iacute tveimur joumlfnum skoumlmmtum IV

C Hyacutedroacutekortiacutesoacuten (Solu-Cortefreg) 150-200 mg IV aacute sex til aacutetta klukkustunda fresti (5-10 mgkg)Minnka skammt niethur iacute ekkert aacute tveimur til fjoacuterum doumlgum eftir einkennum

IV Bloacuteeththornryacutestingshaeligkkandi innrennslislyf ndash VasopressorsA EfedriacutenAdrenaliacutenNorepinephrine 2-12 gmiacuten

B Doacutepamiacuten 2-20 gkgmiacuten

V Ef sjuacuteklingur er aacute -hemjandi meethferethA Gluacutekagon 1-5 mg IV gefieth aacute tveimur til fimm miacutenuacutetum

B Isoacuteproacuteterenoacutel Upphafsskammtur er 2 gmiacuten tiacutetreraeth thornar til aeth hjartslaacutettur er 60 sloumlg aacute miacutenuacutetuogeetha eethlilegum bloacuteeththornryacutestingi hefur verieth naacuteeth

BoumlrnI Adrenaliacuten

11000 001 mgkg IM (= 001 mlkg IM) eetha adrenaliacuten 110000 001 mgkg (=01 mlkg) IV(mest 03-05 mg) THORNennan skammt maacute endurtaka aacute 15 miacutenuacutetna fresti tvisvar sinnum


ndash Difenhyacutedramiacuten 1 mgkg IV IM eetha PO aacute sex klukkustunda fresti iacute aeth minnsta kosti 48 klukku-stundir mest 75 mgskammt

ndash Clemastinum INN (Tavegylreg) 002-006 mgkg skammt eetha 3-6 aacutera 05 mg PO 6-12 aacutera 05-1 mg PO maacute endurtaka aacute 12 klukkustunda fresti

B H2-hemjararndash Ranitidin 1 mgkgskammt IV 2-3 mgkgskammt PO (mest 300 mg) endurtaka eftir 12

klukkustundir ndash Cimetidine 10 mgkgskammt (mest 300 mg) IV eetha PO endurtaka eftir aacutetta klukkustundir

III BarksterarPrednisoacuteloacuten 05-1 mgkg PO iacute tveimur til thornremur joumlfnum skoumlmmtum Solumedrol 1 mgkg IV gefieth aacute30 miacutenuacutetum (skammtur fyrir boumlrn raeligethst af sjuacutekdoacutemsaacutestandi fremur en aldri og staeligreth) maacute endurtakaaacute aacutetta klukkustunda fresti iacute 48 klukkustundir

THORNungaethar konurOumlruggt er talieth aeth nota adrenaliacuten diacutefenhyacutedramiacuten og barkstera THORNoacute er raacuteethlegt aeth gefa efedriacuten 10-15mg IV ( gtgt adreniacutesk aacutehrif hefur minni aacutehrif aacute samdraacutett legs en adrenaliacuten) ef ekki er um liacutefshaeligttu-leg einkenni aeth raeligetha



Houmlfundar

Almennt

Umraeligetha amp freacutettir

Leiethbeiningar um lungnateppuEfnt hefur verieth til aacutetaks til aeth vekja athygli raacuteethamannaheilbrigethisstarfsmanna og almennings um allan heim aacute langvinnri lungnateppusem vaxandi heilbrigethisvandamaacuteli Aacutetakieth nefnist Global initiative forchronic Obstructive Lung Disease skammstafaeth GOLD Til thorness aeth baeligtagreiningu og meethfereth sjuacutekdoacutemsins hafa verieth teknar saman althornjoacuteethlegarleiethbeiningar sem voru gefnar uacutet 4 apriacutel 2001 Aeth leiethbeiningunum standameethal annars WHO og NHLBI (National Heart Lung and Blood Institute iacuteBandariacutekjunum) Styacuterihoacutepur um kliacuteniacuteskar leiethbeiningar hefur aacutekveethieth aethkynna thornaeligr og viacutesa til thorneirra aacute vef Landlaeligknisembaeligttisins Af thornessu tilefnihefur seacuterstakur vinnuhoacutepur verieth stofnaethur og iacute honum eru GunnarGuethmundsson lungnalaeligknir Halldoacuter Joacutensson heimilislaeligknir Joacuten Bjarnarsonheimilislaeligknir og THORNoacuterarinn Giacuteslason lungnalaeligknir Leiethbeiningarnar hafa veriethsendar hoacutepi laeligkna til umfjoumlllunar THORNaeligr hafa thornegar verieth samthornykktar af Feacutelagiiacuteslenskra heimilislaeligkna

AEligskilegt er aeth leiethbeiningar thornessar verethi teknar til faglegrar umfjoumlllunar afsem flestum einstaklingum og seacutergreinafeacuteloumlgum Aacutebendingum um breytingarstuddum heimildum maacute koma til formanns vinnuhoacutepsins THORNoacuterarins Giacuteslasonarthorarig landspitaliis

Leiethbeiningarnar maacute einnig naacutelgast aacute heimasiacuteethu GOLD www goldcopdcom

Workshop Report eru lengstar og iacutetarlegastar

Excutive Summary er nokkueth styttri og thornar er haeliggt er skoetha oumlll atriethileiethbeininganna iacute einu pdf-skjali

Pocket Guide er stuttur uacutetdraacutettur uacuter aethalatriethunum AEligtlunin er aeth birta hann aacuteiacuteslensku siacuteethar



Lyacuteethheilsa Soacutettvarnir Heilbrigethistoumllfraeligethi Kvartanir og kaeligrur

Kliacuteniacuteskar leiethbeiningar Aethrir vefir

Aethrir vefir

Aethrir vefir

meeth kliacuteniacuteskum leiethbeiningum

Tengingar aacute vefi sem annaeth hvort gefa uacutet kliacuteniacuteskar leiethbeiningar eetha dreifa thorneim og gera thornaeligraethgengilegar aacute rafraelignu formi

BandariacutekinAgency for Healhtcare Research and Quality AHRQ aacuteethur AHCPR httpwwwahcprgovclinicNational Guideline ClearinghousehttpwwwguidelinegovSTATICwhatsnewguidelaspview=whatsnewguidelUS Preventive Services Task Force USPSTF og PPIP eetha ldquoPut Prevention Into Practicerdquo httpwwwahcprgovclinicppipixhtmNational Heart Lung and Blood Institute NHLBI httpwwwnhlbinihgovguidelinesindexhtmCenters for Disease Control and Prevention CDC prevention guidelineshttpwondercdcgovwonderprevguidprevguidshtml National Institute of Health NIH Consensus Statements

KanadaCCOHTA httpwwwccohtacaentry_ehtmlBC council on Clinical Practice guidelines httpwwwhlthgovbccamspprotoguidesCanadian Task Force on Preventive health care httpwwwctfphcorgClinical practice guidelines infobase httpmdmcacpgsnewcpgs

Landlaeligknisembaeligttieth - Aethrir vefir

httpwwwlandlaekniristemplate1asppageid=444 (1 of 3) [2122003 225946]


U M R AElig ETH A amp F R Eacute T T I R F R Aacute L A N D L AElig K N I S E M B AElig T T I N U

Erlendar kliacuteniacuteskar leiethbeiningarErlendar kliacuteniacuteskar leiethbeiningar

Iacute TILEFNI THORNESS aeth nuacute eru taeligp thornrjuacute aacuter fraacute thornviacute vinna viethkliacuteniacuteskar leiethbeiningar hoacutefst aacute vegum Landlaeligknis-embaeligttisins viljum vieth kynna thornaeligr erlendu stofnanirsem vieth teljum skara fram uacuter aacute thornessu sviethi Iacute oumlllum til-vikum standa heilbrigethisyfirvoumlld aeth stofnununum ogmeginmarkmieth thorneirra er aeth baeligta gaeligethi auka skil-virkni (effectiveness) og jafnraeligethi iacute heilbrigethisthornjoacuten-ustu meeth gereth kynningu og hagnyacutetingu (implemen-tation) aacute kliacuteniacuteskum leiethbeiningum sem byggja aacute gagn-reyndri laeligknisfraeligethi (evidence based) Sjuacuteklingumal-menningi og heilbrigethisstarfsfoacutelki eru veittar aacutereieth-anlegar leiethbeiningar um bdquobestu vinnubroumlgethldquo (bestpractice) aacute hverjum tiacutema Iacute sumum tilvikum standastofnanirnar liacuteka aeth thornjaacutelfun heilbrigethisstarfsfoacutelks iacutegereth og kynningu aacute kliacuteniacuteskum leiethbeiningum Von-umst vieth til aeth laeligknar og annaeth heilbrigethisstarfsfoacutelkgeti soacutett gagnlegar upplyacutesingar aacute thornessa staethi thornoacutettlistinn seacute ekki taeligmandi

Statens beredning foumlr medicinsk utvaumlrdering (SBU)var stofnueth 1978 iacute thorneim tilgangi aeth vinna gagnryacutenieth uacuterrannsoacuteknum aacute heilbrigethistaeligkni Mat thorneirra naeligr baeligethitil nyacuterrar taeligkni og taeligkni sem er iacute almennri notkuninnan heilbrigethisgeirans Yfir 50 skyacuterslur hafa veriethbirtar eftir uacutetgaacutefudagsetningu aacute wwwsbuse admin

New Zealand Guideline Group var stofnaeth 1996 meeththornaeth aeth meginmarkmiethi aeth thornjaacutelfa heilbrigethisstarfsfoacutelkiacute gereth og kynningu gagnreyndra kliacuteniacuteskra leiethbein-inga Aacute aacuterunum 1998 til 2002 hafa verieth birtar um 40leiethbeiningar og er thorneim raethaeth iacute efnisroumleth Sjaacute wwwnzggorgnz librarycfm

United States Preventive Services Task Force(USPSTF) iacute Bandariacutekjunum eru thornverfagleg samtoumlksem vinna aeth gereth og uacutetbreiethslu kliacuteniacuteskra leiethbein-inga sem byggja aacute gagnreyndri laeligknisfraeligethi odphposophsdhhsgovpubs

National Health and Medical Research Council(NHMRC) iacute Aacutestraliacuteu eru thornverfagleg samtoumlk semvinna meethal annars aeth gereth og uacutetbreiethslu kliacuteniacuteskraleiethbeininga sem byggja aacute gagnreyndri laeligknisfraeligethiYfir 40 leiethbeiningar hafa verieth birtar eftir uacutetgaacutefu-dagsetningu aacute wwwhealthgovaunhmrcpublications

Canadian Task Force on Preventive Health Care(CTFPHC wwwctfphcorg) sem var stofnaeth 1976hefur thornroacuteaeth mjoumlg faacutegaetha aethferethafraeligethi vieth mat aacute gaeligeth-um rannsoacutekna sem nota aacute vieth gereth kliacuteniacuteskra leiethbein-inga Aethferethafraeligethi thornessi er meethal annars notueth afUnited States Preventive Services Task Force semeinnig hefur naacuteieth samstarf aacute oumlethrum sviethum viethCTFPHC Nuacute er buacuteieth aeth vinna leiethbeiningar um yfir200 heilbrigethistengd efni

The Scottish Intercollegiate Guidelines Network(SIGN) sem var stofnaeth 1993 og myndar thornetta netfjoumlldi laeligkna og annarra heilbrigethisstarfsmanna Oumllllaeligknafeacuteloumlg og seacutergreinafeacuteloumlg iacute Skotlandi eiga fulltruacuteathornarna auk fulltruacutea fraacute hjuacutekrunarfraeligethingum lyfja-fraeligethingum tannlaeligknum og oumlethrum starfsgreinum semtengjast heilbrigethismaacutelum SIGN hefur thornegar birt 64leiethbeiningar Sjaacute lista iacute birtingarroumleth aacute www show scotnhsuksignguidelines

National Institute for Clinical Excellence (NICE) varstofnaeth iacute apriacutel 1999 sem seacuterstoumlk heilbrigethisstofnun(Special Health Authority) fyrir England og WalesStofnunin er hluti af National Health Service (NHS)og stendur aeth uacutetgaacutefu annars vegar aacute kliacuteniacuteskum leieth-beiningum (niacuteu birtar) og hins vegar heilbrigethis-taeligkniuacutettektum (health technologies (including medi-cines medical devices diagnostic techniques andprocedures)) sem nuacute eru ruacutemlega 50 talsins og maacutenaacutelgast aacute wwwniceorguk

Guideline Development Department Dutch Institutefor Healthcare Improvement (CBO) www cbonlYfir 50 skyacuterslur hafa verieth birtar en einungis aacute hol-lensku enn sem komieth er Sjaacute wwwcbonl product richtlijnen

Vakin er athygli aacute aeth meeth thornviacute aeth nota vefuacutetgaacutefuLaeligknablaethsins er auethvelt aeth smella beint aacute sloacuteethirnartil aeth komast aacute viethkomandi heimasiacuteethur

Styacuterihoacutepur umkliacuteniacuteskarleiethbeiningar

Ari Joacutehannesson laeligknir formaethur

Einar Magnuacutessonlyfjafraeligethingur

Gunnar Toacutemasson laeligknir Halldoacuter Joacutensson laeligknirHaukur Valdimarsson laeligknir Rannveig Einarsdoacutettir

kliacuteniacuteskur lyfjafraeligethingur Sigurethur Guethmundsson

landlaeligknir Sigurethur Helgason laeligknir

ritstjoacuteri Sveinn Magnuacutesson laeligknir

SEARCH NICE

Advancedraquo

Welcome to NICE Technology Appraisals Completed Appraisals 23 February 2003

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Completed AppraisalsAll guidance documents for completed technology appraisals are listed below

For the documents and related material click on the title in the list The list can be sorted by referencenumber title (alphabetically) wave number and date of publication - simply click on the relevant columnheading in the blue box once or twice depending on the whether you want an ascending or descending listFor more information on using the list and the terms and abbreviations used click here

No Title Wave Publication

Date Review

Date

33 Advanced Colorectal Cancer - irinotecan oxaliplatinamp raltitrexed (NO 33)

3 January 2002 April 2005

19 Alzheimers disease - donepezil rivastigmine andgalantamine (N0 19)

2 January 2001 December 2003

11 Arrhythmias - implantable cardioverter defibrillators(N0 11)

2 September 2000 September 2003

38 Asthma - inhaler devices for older children (No 38) 4 April 2002 April 2005

10 Asthma - inhalers for children under five (N0 10) 1 August 2000 August 2003

13 Attention deficit hyperactivity disorder (ADHD) -methylphenidate (N0 13)

2 October 2000 August 2003

23 Brain cancer - temozolomide (N0 23) 2 April 2001 March 2004

6 Breast cancer - taxanes (N0 6) 1 June 2000 September 2001

30 Breast cancer - taxanes - review (N0 30) R September 2001 August 2003

34 Breast cancer - trastuzumab (NO 34) 3 March 2002 April 2005

54 Breast Cancer - Vinorelbine (No 54) 3 December 2002 June 2005

5 Cervical smear tests - liquid based cytology (N0 5) 1 June 2000 May 2003

17 Colorectal cancer - laparoscopic surgery (N0 17) 2 December 2000 August 2003

40 Crohns disease (No 40) 4 March 2002 May 2005

51 Depression and anxiety - computerised cognitivebehaviour therapy (No 51)

October 2002 June 2005

21 Diabetes (type 2) - pioglitazone (N0 21) 2 March 2001 August 2002

9 Diabetes (type 2) - rosiglitazone (N0 9) 1 August 2000 August 2002

53 Diabetes - Long acting insulin analogues (No 53) 6 December 2002 November 2005

7 Dyspepsia - proton pump inhibitors (N0 7) 1 July 2000 June 2003

15 Flu - zanamivir (Relenza) (N0 15) 2 November 2000 June 2002

12 Glycoprotein IIbIIIa inhibitor guidance for acutecoronary syndromes (N0 12)


47 Glycoprotein IIbIIIa inhibitor guidance for acutecoronary syndromes - review (NO 47)

R September 2002 July 2005

Completed Appraisals - NICE

httpwwwniceorgukcatta1aspc=153 (1 of 3) [2322003 114029]

Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit

Faacutemenn thornjoacuteeth aacute aeth nyacuteta vandaethefni fraacute oumlethrumNyacutetur traustsAlthornjoacuteethaheilbrigethisstofnunarinnar

Almennt

Leiethbeiningarnar hafa veriethgerethar aethgengilegar aacute vef umkliacuteniacuteskar leiethbeiningar sem er aethfinna aacute heimasiacuteethu landlaeligknisUmsjoacuten meeth gereth thorneirra hefurstyacuterihoacutepur um kliacuteniacuteskarleiethbeiningar undir stjoacutern AraJoacutehannessonar og ritstjoacuternSigurethar Helgasonar


Skotar framarlega iacute flokkivieth gereth kliacuteniacuteskraleiethbeiningaIacute thornessum pistli verethur vakin athygli aacute voumlnduethu efni um kliacuteniacuteskarleiethbeiningar sem Skotar hafa unnieth og birt aacute netinu Aacute vefilandlaeligknisembaeligttisins - wwwlandlaekniris - er tengill aacute thornennanskoska vef en auk thorness er sloacuteethin birt heacuter aeth aftan

Scottish Intercollegiate Guidelines Network (SIGN) var stofnaeth 1993og eins og nafnieth gefur til kynna myndar thornetta net fjoumlldi laeligkna ogannarra heilbrigethisstarfsmanna Meethal annars eiga thornarna fulltruacutea oumllllaeligknafeacuteloumlgseacutergreinafeacuteloumlg iacute Bretlandi auk thorness sem thornarna eru fulltruacutearfraacute hjuacutekrunarfraeligethingum lyfjafraeligethingum tannlaeligknum og oumlethrumstarfsgreinum sem tengjast heilbrigethismaacutelum Houmlfuethstoumlethvar SIGN eruiacute huacutesnaeligethi skoska laeligknafeacutelagsins iacute Edinborg og nyacutetur thornessi virtastofnun mikils stuethnings laeligknafeacutelagsins og einstakra fagfeacutelaga

Faacutemenn thornjoacuteeth aacute aeth nyacuteta vandaeth efni fraacute oumlethrum

Suacute aacutekvoumlrethun styacuterihoacuteps um kliacuteniacuteskar leiethbeiningar aacute Iacuteslandi aeth bendaheilbrigethisstarfsfoacutelki aacute leiethbeiningar SIGN byggist aacute eftirtoumllduVinnulag vieth gereth SIGN leiethbeininga er mjoumlg vandaeth (val verkefnaheimildarvinna samsetning vinnuhoacutepa) og lyacutetur viethurkenndumgaeligethakroumlfum Leitast er vieth aeth koma sannreyndum (evidence based)vinnubroumlgethum iacute notkun thornannig aeth gagnast megiheilbrigethisthornjoacutenustunni Raacuteethleggingar innan leiethbeininga eru beinttengdar thorneim viacutesindalega grunni sem aeth baki liggur thornegar thorness erkostur Leiethbeiningarnar faacute mjoumlg viacuteethtaeligka kynningu sem droumlg ogboethieth er upp aacute umraeligethur (fundi) meethal heilbrigethisstarfsmanna umeinstakar leiethbeiningar aacuteethur en aeth formlegri uacutetgaacutefu kemur Aacute thornessumfundum hafa allir reacutett aacute aeth koma skoethunum siacutenum aacute framfaeligri

Framsetning leiethbeininganna thornoacutetti mjoumlg aethgengilegheildarleiethbeiningar og siacuteethan einnar til fjoumlgurra blaethsiacuteethna aacutegrip (quickreference) Faacutemenn thornjoacuteeth hefur minni toumlk aacute aeth vinna mikinn fjoumlldaleiethbeininga og henni er thornviacute nauethsynlegt aeth nyacuteta vinnu annarra seacutethorness nokkur kostur

Nyacutetur trausts Althornjoacuteethaheilbrigethisstofnunarinnar

SIGN vinnur iacute naacuteinni samvinnu vieth heilbrigethisyfirvoumlld ogsjuacuteklingasamtoumlk vieth gereth leiethbeininga Nyacuteverieth var stofnunin valin tilaeth hafa umsjoacuten meeth leiethbeiningum uacutetgefnum afAlthornjoacuteethaheilbrigethisstofnuninni og maacute aeligtla aeth thornaeth hafi komieth til vegna

Clinical Guidelines - Numerical List

Items marked are available in Acrobat format (info)

No Guideline TitleQuick

referenceguide

Fullguideline

PublicationDate

66Diagnosis and managementof childhood otitis media inprimary care (185K) (687K)

February2003

65 The immediate dischargedocument

IDDtemplate(261K) (611K)

January 2003

64

Management of patients withstroke rehabilitationprevention and managementof complications anddischarge planning

(217K) (914K)November

2002

63 British Guideline on themanagement of asthma (656K) (in sections)

January 2003

62 Prophylaxis of venousthromboembolism (290K) (11MB)

October 2002

61 Investigation ofpost-menopausal bleeding (262K) (723K)

September2002

60 Postnatal depression andpuerperal psychosis (198K) (741K)

June 2002

59Community management oflower respiratory tractinfection in adults (133K) (392K)

June 2002

58Safe sedation of childrenundergoing diagnostic andtherapeutic procedures (198K) (782K)

February2002

57 Cardiac rehabilitation(76K) (357K)

January 2002

56Prevention and managementof hip fracture in olderpeople

(225K) (974K)

January 2002

55 Management of diabetes(462K) (926K)

November2001


httpwwwsignacukguidelinespublishednumlisthtml (1 of 4) [2322003 120120]

Sigurethur Helgason

131313

13131313

13

13

Scottish Intercollegiate Guidelines NetworkThe British Thoracic Society

British Guideline on theManagement of Asthma

British Association for Accident and Emergency

Medicine

General PracticeAirways Group

Royal College of Paediatricsand Child HealthRoyal Paediatric

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Royal College of Physiciansof London

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Information on the full guideline produced by the National Collaborating Centre for Mental Healthfrom which the NICE guideline has been prepared is given in Section 6 of the NICE guideline

Clinical Guideline 1SchizophreniaCore interventions in the treatment and management of schizophrenia in primary and secondary care

Issue dateDecember 2002

The algorithms and pathways to care on this poster form part of the NICE guideline onschizophrenia (see above) Copies of the NICE guideline can be obtained free of charge from theNICE website (wwwniceorguk) and from the NHS Response Line (phone 0870 1555 455 andquote reference number N0176) A version for people with schizophrenia their advocates andcarers and the public called Treating and managing schizophrenia (core interventions)is alsoavailable from the website and the NHS Response Line (quote reference number N0177 for anEnglish-only copy and N0178 for a copy that has the text in both English and Welsh)

This guidance is written in the following contextThis guidance represents the view of the Institute which was arrived at after carefulconsideration of the evidence available Health professionals are expected to take it fully intoaccount when exercising their clinical judgment The guidance does not however override theindividual responsibility of health professionals to make decisions appropriate to thecircumstances of the individual patient in consultation with the patient andor guardian or carer

National Institute for Clinical Excellence

11 StrandLondon WC2N 5HR

wwwniceorguk

ISBN 1-84257-257-1Published by the National Institute for Clinical ExcellenceDecember 2002Design by Anytime After 9 LtdPrinted by Abba Litho Sales Limited London

copyCopyright National Institute for Clinical Excellence December 2002 All rights reserved This material may be freelyreproduced for educational and not-for-profit purposes within the NHS No reproduction by or for commercialorganisations is allowed without the express written permission of the National Institute for Clinical Excellence

SchizophreniaCore interventions in the treatment andmanagement of schizophrenia in primary andsecondary care

Clinical practice algorithms and pathways to careDecember 2002

Developed by the National Collaborating Centre for Mental Health

Guidance on theuse of debridingagents and specialist wound care clinics fordifficult to healsurgical wounds

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Summary and Conclusions

Prevention Diagnosisand Treatment of VenousThromboembolismA Systematic Review

The Swedish Council on Technology Assessment in Health Care

CARDIACREHABILITATIONSUMMARY ANDRESOURCE KIT

BEST PRACTICEEVIDENCE-BASEDGUIDELINE

AUGUST 2002

Exercise-Based Cardiac Rehabilitation Programs for Coronary Artery Disease A Systematic Clinical and Economic Review

Technology Report

Issue 34 March 2003

v

assessment From these 99 articles 5 new EX CR trials and 5 new CCR trials were included in our review The 10 new trials are more recent than those included in the Cochrane review which included 36 trials That brings the total number of trials analysed in our meta-analysis to 46 The clinical meta-analysis found that CCR showed a trend toward reduction in total mortality although this was not statistically significant (RR 087 95 CI 074 to 102) However cardiac mortality was reduced (RR 080 95 CI 065 to 099) EX CR reduced total mortality (RR 076 95 CI 059 to 098) and reduced cardiac mortality (RR 073 95 CI 056 to 096) Health related quality of life (HRQoL) outcomes were not pooled but there was evidence of a consistent improvement in HRQoL across the nine trials reporting this outcome although few studies showed improvement above that measured in the usual care groups Meta-regression analysis failed to demonstrate the presence of any significant sub-group effects Sub-groups analysed included EX CR or CCR duration of program intensity of program follow-up period all post MI or other than just MI patients gender age trials pre- or post-1995 and quality of trials In the review of economic evidence 614 potentially relevant studies were found Of these 64 were retrieved for full text assessment and 6 were ultimately included in the review Three were full economic evaluations and 3 were cost studies Only 1 included study was RCT-based It was an economic evaluation located in Canada and concluded that an eight-week supervised exercise plus counselling program cost US$9200 per QALY and US$21800 per life-year gained during the year of follow-up Another Canadian-based economic evaluation found that it costs less than US$15000 per year of life saved for a supervised CR program for men A US study found that it cost US$4950 per year of life saved through CR The cost studies based in Sweden and the US concluded that CR may be cost saving compared to standard care for patients with CAD due to lower rehospitalization rates and lower mean patient costs Conclusions The systematic review of clinical evidence supports the findings of the previous Cochrane review in that CR which includes exercise has beneficial effects on cardiac mortality and total mortality (although the trend for CCR on total mortality was not significant) It appears that CCR has a somewhat more positive effect overall on risk factors than EX CR Few studies have examined the impact of CR on HRQoL and in those that have there was a non-significant trend that CR which includes exercise enhances quality of life relative to usual care Although recent trials have increasingly recruited patients who have had revascularization or angina the representation of women and the elderly in the trials remains poor The long-term (ie 10 years or more) mortality benefit of CR tends to diminish This may be associated with a reduction in exercise behaviour The results of the included economic studies were consistent in that the three full economic evaluations all suggested CR which includes exercise is cost-effective and the three cost studies all suggested CR which includes exercise may reduce costs to health care systems due to reduced rehospitalization and drug utilization Although the cost studies suggest that over time cost savings would result from switching to CR from standard care in the short term there would likely be a significant budget impact For example at an average cost of C$1000 per patient making supervised cardiac rehabilitation standard practice for Canadian CAD patients could increase short run annual expenditures in Canada by C$225 million

Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Anna OacutelafsdoacutettirBjoumlrnsson

Yfirlit

AethdragandinnLeiethbeiningar

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Gaeligethi laeligknisthornjoacutenustu aukinmeeth vefi um kliacuteniacuteskarleiethbeiningarAacute vegum landlaeligknisembaeligttisins hefur verieth unnieth aeth thornviacute aacute undanfoumlrnummisserum aeth byggja upp vef undir heitinu Kliacuteniacuteskrar leiethbeiningar THORNegarer komieth talsvert efni aacute vefinn en 26 vinnuhoacutepar hafa unnieth aeth gereth thornessSjouml thorneirra hafa thornegar uacutetbuacuteieth efni sem er komieth aacute vefinn yacutemist tilbuacuteieth eetha iacutevinnslu Alls hafa um 70 laeligknar tekieth thornaacutett iacute vinnslu efnisins auk foacutelks uacuteroumlethrum heilbrigethissteacutettum Vefurinn er vistaethur aacute heimasiacuteethulandlaeligknisembaeligttisins wwwlandlaekniris undir LeiethbeiningarEftirlit aacutevalstiku vinstra megin aacute siacuteethunni Auk thorness hefur thornaeth efni sem er tilbuacuteiethverieth gefieth uacutet aacute geisladiski aacutesamt vefnum Lyfjavali 2000 Iacute biacutegereth erennfremur aeth helstu aacutehersluatriethi sem birt eru aacute yfirlitssiacuteethu hversmaacutelaflokks aacute vefnum verethi uacutetbuacutein sem ploumlstueth minnisbloumleth THORNaeth verkefni ernokkueth dyacutert og verethur sennilega haacuteeth thornviacute aeth fjaacutermagn faacuteist til verksins

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Aethdragandinn

Aethdragandinn aeth gereth kliacuteniacuteskra leiethbeininga aacute netinu er saacute aeth leitaeth var tilSigurethar Helgasonar heilsugaeligslulaeligknis iacute Aacuterbaelig siacuteethla aacuters 1999 og hannbeethinn aeth taka aeth seacuter ritstjoacutern thornessa vefjar Hann var ekki meeth oumllluoacutekunnur sliacutekri uppbyggingu eftir aeth hafa unnieth aeth hliethstaeligethu verkefni semfjallaethi um Lyfjaval Fagraacuteeth Laeligknafeacutelags Iacuteslands undir forystu PaacutelmaJoacutenssonar hafethi thornaacute um eins aacuters skeieth unnieth aeth tilloumlgum um gereth kliacuteniacuteskraleiethbeiningar og sett fram moacutetaethar hugmyndir thornar aeth luacutetandi (Laeligknablaethieth1999 851004) THORNaeth sem yacutetti thornessu af staeth var aeth iacute loumlndunum allt iacutekringum okkur er mikieth af sliacuteku efni Vieth houmlfethum dregieth lappirnar svoliacutetiethiacute thornessum efnum og laeligknar sem soacutett hafa menntun siacutena til yacutemissa landa hafanotast vieth thornaeligr leiethbeiningar sem thornekkja uacuter naacutemi siacutenu og stoumlrfum erlendisSigurethur var fyrst raacuteethinn til eins aacuters og aeth thornviacute loknu var raacuteethning hans

Aacute thornessari siacuteethu eru aeth finna tengla aacute helstu kliacuteniacutesku leiethbeiningarnar fyrir krabbamein ATH Siacuteethan er iacute vinnslu

StaethurSjuacutekdoacutemaflokkur

SOR (The SOR Project of the National Federation of French Cancer Centers Clinical PracticeGuidelines in Oncology)

GynecologicalCancers

GastrointestinalCancer

Hemopathy Head and NeckCancer

Lung Cancer Other cancertypes

Ovarian Cancer Carcinoma of thecolon

Hodgkins Disease Malignant tumours ofthe salivary glands

Malignantmesothelioma

Epithelial tumours ofthe thymus

Carcinoma of thecervix

Hepatocellularcarcinoma

Epidermoid cancersof the oropharynx

Osteosarcoma

Cancer of theendometrium

Carcinoma of theoesophagus

Cancer of the rectum

Cancer Care OntarioBreastCancer


GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer

Hematology LungCancer

ApprovedPracticeGuidelines

Approved PracticeGuidelines






PracticeGuidelines inProgress

Practice Guidelinesin Progress






ApprovedEvidenceSummaries

Approved EvidenceSummaries





EvidenceSummaries inProgress






Melanoma Neuro-OncologyPediatricCancer

Sarcoma SupportiveCare

SystemicTreatment



Practice Guidelines Approved PracticeGuidelines

PracticeGuidelines










ASCO American Society of Clinical Oncology BreastCancer

ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers

AntiemeticAnemiaplatelettransfusions

ColonyStimulatingFactorsProtecants

SOR

httpwwwkmlshiskl1htm (1 of 4) [2422003 143742]

The Role ofBisphosphonatesin Breast Cancer

2000 Updateof ColorectalCancerSurveillanceGuidelines

UnresectableNon-Small-CellLung Cancer

The Role OfBisphosphonatesIn MultipleMyeloma

1997 Update ofRecommendationsfor the Use ofTumor Markers inBreast andColorectal Cancer

Recommendations forthe Use of Antiemetics

1996 Update ofRecommendations forthe Use ofHematopoieticColony-StimulatingFactors

RecommendedBreast CancerSurveillance

RecommendedColorectalCancerSurveillanceGuidelines

Tumor Markers inBreast andColorectal Cancer

Use of Epoetin inPatients With Cancer


PostmastectomyRadiotherapy

Platelet Transfusion forPatients With Cancer

Use of HematopoieticColony-StimulatingFactorsEvidence-BasedPractice Guidelines

1998 Update ofRecommendedBreast CancerSurveillanceGuidelines

The Use ofChemotherapy andRadiotherapyProtectants

NICE (National Institute for Clinical Excellence)Brain Cancer Breast

CancerCervicalSmear Tests

ColorectalCancer

Leukaemia Lung Cancer Lymphoma

Brain cancer -temozolomide(N0 23)

Breast cancer -taxanes (N0 6)

Cervical smeartests - liquidbased cytology(N0 5)

AdvancedColorectalCancer -irinotecanoxaliplatin ampraltitrexed (NO33)

Leukaemia(chronic myeloid)- imatinib (N0 50)

Lung cancer -docetaxelpaclitaxelgemcitabine andvinorelbine (N026)

Lymphoma(follicularnon-Hodgkins) -rituximab (no 37)

Breast cancer -taxanes - review(N0 30)

Colorectalcancer -laparoscopicsurgery (N0 17)

Leukaemia(lymphocytic) -fludarabine (N029)

Breast cancer -trastuzumab (NO34)

Breast Cancer -Vinorelbine (No54)

OvarianCancer

PancreaticCancer

Ovarian cancer(advanced) -PLDH (Caelyx)(No45)

Pancreaticcancer -gemcitabine (N025)

Ovarian Cancer -paclitaxel (No55)

Ovarian cancer -taxanes (N0 3)

Ovarian cancer -topotecan (N028)

SOR


The Periodic Maintenance Lubrication Intervals schedule is taken directly from a 1980 edition Suzuki FS50 factory owners manual

Before starting any work always consult the manual for your scooters model amp year and be sure you know what youre doing

MethodologyQuestions set by a multidisciplinary groupLiterature searches using these questionsMeta-analyses randomised controlled trials

required for A recommendationParticular attention paid to

ndash study size ITT analysesndash predefined goals

Levels of Evidence for Databull Level 1 Randomized controlled trials (RCTs) with

sufficient numbers or good quality meta-analyses based on RCTs

bull Level 2 RCTs with smaller numbers (therefore insufficient power)

bull Level 3 Non-randomized controlled or cohort studies case series case-controlled or cohort studies cross sectional or high quality retrospective studies

bull Level 4 Evidence based on the published opinion of expert committees for example consensus guidelines committees

bull Level 5 Evidence which expresses the opinion of the committee member(s) who have reviewed the literature and guidelines following discussion with peers

See also Italian

COCHRANE DEPRESSION ANXIETYAND NEUROSIS GROUP

Abstracts of Cochrane Reviews

The Cochrane Library Issue 1 2003The full text of these reviews and protocols is available in The Cochrane Library

indicates the review is new in the current release of the Library indicates the review has been substantially amended since the last issue of the

Library

Note Protocols are the introduction objectives materials and methods for reviewscurrently being prepared and do not therefore have abstracts

Whats new in this issue

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About The Cochrane Library

Reviews

Active placebos versus antidepressants for depression (Cochrane Review)

Antidepressant and benzodiazepine for major depression (Cochrane Review)

Antidepressant treatment for post-natal depression (Cochrane Review)

Antidepressants for depression in medical illness (Cochrane Review)

Antidepressants versus placebo for the depressed elderly (Cochrane Review)

Antidepressants versus psychological treatments and their combination for bulimianervosa (Cochrane Review)

Antidepressants versus placebo for people with bulimia nervosa (Cochrane Review)

Cognitive behaviour therapy for chronic fatigue syndrome in adults (Cochrane Review)

Drugs versus placebo for dysthymia (Cochrane Review)

Effectiveness and cost effectiveness of counselling in primary care (Cochrane Review)

Interventions for pathological gambling (Cochrane Review)

Interventions for preventing eating disorders in children and adolescents (CochraneReview)

Interventions for vaginismus (Cochrane Review)

Kava extract for treating anxiety (Cochrane Review)

Lithium for maintenance treatment of mood disorders (Cochrane Review)

Melatonin for the prevention and treatment of jet lag (Cochrane Review)

Pharmacotherapy for Posttraumatic Stress Disorder (Cochrane Review)

Psychological debriefing for preventing post traumatic stress disorder (PTSD) (CochraneReview)

Psychosocial and pharmacological treatments for deliberate self harm (CochraneReview)

COCHRANE DEPRESSION ANXIETY AND NEUROSIS GROUP abstracts

httpwwwupdate-softwarecomabstractsg240indexhtm (1 of 3) [2242003 203324]

Psychotherapy for bulimia nervosa and binging (Cochrane Review)

Selective serotonin reuptake inhibitors (SSRIs) for depression (Cochrane Review)

St Johns wort for depression (Cochrane Review)

The use of antidepressants for Generalized Anxiety Disorder (This review has beenwithdrawn by the editorial group Abstract not available)

Transcranial magnetic stimulation for treating depression (Cochrane Review)

Treatment discontinuation with selective serotonin reuptake inhibitors (SSRIs) versustricyclic antidepressants (TCAs) (Cochrane Review)

Tricyclic drugs for depression in children and adolescents (Cochrane Review)

Tryptophan and 5-Hydroxytryptophan for Depression (Cochrane Review)

Valproate for acute mood episodes in bipolar disorder (Cochrane Review)

Valproic acid valproate and divalproex in the maintenance treatment of bipolar disorder(Cochrane Review)

Protocols

5HT-1 agonists for generalized anxiety (Cochrane Protocol)

A comparison of active drugs for the treatment of dysthymia (Cochrane Protocol)

Acupuncture for depression (Cochrane Protocol)

Amitriptyline versus other tricyclic drugs and selective serotonin reuptake inhibitors(SSRIs) for depression (Cochrane Protocol)

Antidepressant dose-increase for non-responders to a standard dose for depression(Cochrane Protocol)

Antidepressants alone versus psychotherapy alone for depression (Cochrane Protocol)

Antidepressants for depressed elderly (Cochrane Protocol)

Antidepressants for bipolar depression (Cochrane Protocol)

Benzodiazepines for generalized anxiety (Cochrane Protocol)

Brief cognitive-behavioural therapies versus other brief psychological therapies fordepression (Cochrane Protocol)

Brief psychological therapies versus treatment as usual for depression (CochraneProtocol)

Carbamazepine for bipolar affective disorders (Cochrane Protocol)

Combinations of pharmacotherapy and psychotherapy for depression (CochraneProtocol)

Duration of treatment with antidepressants in depressive disorder (Cochrane Protocol)

Electroconvulsive therapy for depressed elderly (Cochrane Protocol)

Exercise therapy for depression and other neurotic disorders (Cochrane Protocol)

Exercise therapy for chronic fatigue syndrome (Cochrane Protocol)

Folate for depressive disorders (Cochrane Protocol)

Gabapentin in the treatment of acute affective episodes in bipolar disorderefficacy andacceptability (Cochrane Protocol)

Individual psychotherapy in the outpatient treatment of adults with anorexia nervosa(Cochrane Protocol)

Initial high dose versus standard dose of antidepressants for depression (CochraneProtocol)

Inositol for depressive disorders (Cochrane Protocol)



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No one can keep up to date with therelevant evidence in their field ofinterest The major bibliographicdatabases cover less than half theworlds literature and are biased towardsEnglish language publications Of theevidence available in the majordatabases only a fraction can be foundby the average searcher Textbookseditorials and reviews which have notbeen prepared systematically may beunreliable Much evidence isunpublished but unpublished evidencemay be important More easilyaccessible research reports tend toexaggerate the benefits of interventions

The Cochrane Library solves many ofthese problems Published on aquarterly basis and made available bothon CD-ROM and the Internet (see Howto get access) it is the best singlesource of reliable evidence about theeffects of health care

The Cochrane Library consists of aregularly updated collection ofevidence-based medicine databasesincluding The Cochrane Database ofSystematic Reviews - evidence basedsystematic reviews prepared by theCochrane Collaboration which providehigh quality information to peopleproviding and receiving care and those

AbstractsThe Abstracts of Cochrane Reviews areavailable without charge and can bebrowsed or searched

Quick Reference CardA quick reference card offering usefulinformation and tips about using the newinternet version of The Cochrane Library isnow available in PDF format Click here todownload a copy Please acknowledgeUpdate Software as the source of this guideif you wish to distribute it for trainingpurposes

Further useful reference materialNICS user guide to The Cochrane LibraryCRD training and reference material

Provisional Publication Dates for 2003

Issue 1 2003 20 January 2003Issue 2 2003 22 April 2003Issue 3 2003 21 July 2003Issue 4 2003 20 October 2003


httpwwwupdate-softwarecomcochranedefaulthtm (1 of 2) [2242003 203417]

A substantive amendment to this systematic review was last made on 18 November 2002 Cochrane reviews are regularly checked and updated if necessary

Background Bipolar disorder is a common debilitating illness characterised by acute affective episodes with full or partial inter-episode remission Effective and acceptable treatment of acute episodes is required Valproate has become a leading adjunctive and alternative mood stabilising treatment to lithium in bipolar disorder

Objectives To determine the efficacy and acceptability of valproate in the treatment of acute episodes of bipolar disorder

Search strategy The search included the Cochrane Collaboration Depression Anxiety and Neurosis Controlled Trials Registrar (CCDANCTR) the Cochrane Controlled Clinical Trials Register (CCTR) reference lists of relevant papers and books and contact with authors of trials experts and pharmaceutical companies

Selection criteria Randomised controlled trials comparing valproate with placebo other mood stabilisers and antipsychotic medication in the treatment of any bipolar affective episode Participants were of both sexes of all ages with a diagnosis of bipolar affective disorder approximating to ICD 10 Code F31and DSM IV 296

Data collection and analysis Methodological quality was assessed independently by two reviewers blind to the authorship and source of papers

Ten randomised controlled trials were found comparing valproate with other interventions in mania None was found examining its use in depression or mixed affective episodes Data were extracted on the main outcome failure to respond by the end of the study assessed by a less than 50 reduction in the Young Mania Rating Scale or the SADS-S mania scale Three trials (316 participants) compared valproate with placebo Three trials (158 participants) compared valproate with lithium Two trials (363 participants) compared valproate with olanzapine One trial (36 participants) compared valproate with haloperidol Two trials (59 patients) compared valproate with carbamazepine

Acceptability of treatment was estimated using the outcome measure total number of subjects withdrawing from the study Three trials (321 patients) contributed to the comparison between valproate and placebo two studies (144 patients) contributed to the comparison with lithium One study (30 patients) provided data on this outcome in the comparison between valproate and carbamazepine Pooled relative risks (with 95 confidence intervals) were calculated using fixed effect approaches

Main results Valproate was more efficacious than placebo (RRR 38 RR 062

From The Cochrane Library Issue 1 2003 Oxford Update Software Ltd All rights reserved


Macritchie K Geddes JR Scott J Haslam D de Lima M Goodwin G

ABSTRACT

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of 2Valproate for acute mood episodes in bipolar disorder (Cochrane Review)

2242003httpwwwupdate-softwarecomabstractsab004052htm

95 CI 051 to 077) in the treatment of mania There was no significant difference between valproate and lithium (RRI 5 RR 105 95 CI 074-150) or between valproate and carbamazepine (RRR 34 RR 066 95 CI 038 to 116) Valproate was less effective than olanzapine (failure to achieve clinical response RRI 25 RR 125 95 CI 101 to 154 average of 28 point less change on the Mania Rating Scale (95 CI 083 to 479) There were no significant differences in acceptability as measured by total number of subjects withdrawing from the study There were significant differences in the side effect profiles of valproate and olanzapine with more sedation and weight gain on olanzapine

Reviewers conclusions There is consistent if limited evidence to suggest that valproate is an efficacious treatment for acute mania Valproate may be less effective than olanzapine but may cause less sedation and weight gain More well designed randomised controlled trials investigating the relative efficacy and acceptability of valproate in the treatment of the full range of acute affective episodes occurring in bipolar disorder are required

Citation Macritchie K Geddes JR Scott J Haslam D de Lima M Goodwin G Valproate for acute mood episodes in bipolar disorder (Cochrane Review) In The Cochrane Library Issue 1 2003 Oxford Update Software

This is an abstract of a regularly updated systematic review prepared and maintained by the Cochrane

Collaboration The full text of the review is available in The Cochrane Library (ISSN 1464-780X)

The Cochrane Library is prepared and published by Update Software Ltd All rights reserved

See wwwupdate-softwarecom or contact Update Software infoupdatecouk for information on subscribing to The Cochrane Library in your area

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Page 2 of 2Valproate for acute mood episodes in bipolar disorder (Cochrane Review)


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1 PREMEDLINE Ulrich ML Rotzinger S Asghar SJ Jurasz P Tanay VA Dunn SM Radomski M Greenshaw A Silverstone PH Effects of dextroamphetamine lithium chloride sodium valproate and carbamazepine on intraplatelet Ca2+ levels [Journal Article] Journal of Psychiatry amp Neuroscience 28(2)115-25 2003 March

bull

2 MEDLINE Oluboka OJ Bird DC Kutcher S Kusumakar V A pilot study of loading versus titration of valproate in the treatment of acute mania [Clinical Trial Journal Article Randomized Controlled Trial] Bipolar Disorders 4(5)341-5 2002 Oct UI 12479668

bull

Pre-MEDLINE MEDLINE

Search History Results Display

1(controlled or randomized or double blind or sham or placebo)mp [mp=ti ab rw sh]

332920

2 (depression or bipolar or depressed)mp [mp=ti ab rw sh] 161368

3 valproatemp [mp=ti ab rw sh] 3958

4 2 and 3 377

5 1 and 4 104

6 limit 5 to human [Limit not valid in Pre-MEDLINE records were retained] 103

7 6 not reviewmp [mp=ti ab rw sh] 84

Enter Keyword or phrase

Abstracts English Language Review Articles EBM Reviews Human Latest Update Ovid Full Text Available

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Background Constraints on resources and time often render treatments for anxiety such as psychological interventions impracticable while synthetic anxiolytic drugs are effective but are often burdened with adverse events Options which are effective and safe would be of considerable interest and a welcome addition to the therapeutic repertoire

Objectives To assess the effectiveness and safety as reported in rigorous clinical trials of kava extract compared with placebo for treating anxiety

Search strategy All publications describing (or which might describe) randomised double-blind placebo-controlled trials of kava extract for anxiety were sought through electronic searches on EMBASE MEDLINE AMED (British Library) CISCOM (Research Council for Complementary Medicine London) CentralCCTR and CCDANCTR The search terms that were used were kava kawa kavain Piper methysticum and Rauschpfeffer (German common name for Piper methysticum) Additionally manufacturers of kava preparations and experts on the subject were contacted and asked to contribute published and unpublished material Hand-searches of relevant medical journals (Erfahrungsheilkunde 1996 - 2002 Forsch Komplementaumlrmed Klass Naturheilkd 1994 - 2002 Phytomed 1994 - 2002 Alt Comp Ther 1995 - 2002) conference proceedings (eg FACT - Focus on Alternative and Complementary Therapies 1996 - 2002) and our own files were conducted The searches were updated to August 2002 No restrictions regarding the language of publication were imposed

Selection criteria To be included studies were required to be randomised controlled trials (RCTs) ie trials with a randomised generation of allocation sequences and conducted placebo-controlled and double-blind ie trials with blinding of patients and care providers Trials using oral preparations containing kava extract as the only component (mono-preparation) were considered Trials using single constituents of kava extract alone assessing kava extract as one of several active components in a combination preparation or as a part of a combination therapy were excluded

Data collection and analysis Data were extracted systematically according to patient characteristics interventions and results Methodological quality of all trials was evaluated using the standard scoring system developed by Jadad and colleagues The screening of studies selection data extraction validation and the assessment of methodological quality were performed independently by the two reviewers Disagreements in the evaluation of individual trials were resolved through discussion


Kava extract for treating anxiety (Cochrane Review) Pittler MH Ernst E

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Page 1 of 2Kava extract for treating anxiety (Cochrane Review)


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Underlined text links to on-line full-text or medline abstractFor an exhaustive bibliography of everything having to do with pharmaceuticalpromotion visit Healthy Skepticism

Original StudiesAttitudes and Practices

Gibbons RV Landry FJ Blouch DL et al A comparison of physicians and patientsattitudes toward pharmaceutical industry gifts JGIM 1998 13151-154

Hodges B Interactions with the pharmaceutical industry experiences and attitudes ofpsychiatry residents interns and clerks CMAJ 1995 Sep 1153(5)553-9

Lurie N Rich EC Simpson DE et al Pharmaceutical representatives in academicmedical centers Interaction with faculty and housestaff J Gen Int Med 19905240-243

Mainous III AG Hueston WJ Rich EC Patient perceptions of physician acceptance ofgifts from the pharmaceutical industry Arch Fam Med 4 1995 335-9

McKinney WP Schiedermayer DL Lurie N et al Attitudes of internal medicine facultyand residents toward professional interaction with pharmaceutical sales representativesJAMA 1990 Oct 3264(13)1693-7

Steinman MA Shlipak MG McPhee SJ Of principles and pens attitudes and practicesof medicine housestaff toward pharmaceutical industry promotions Am J Med 2001May110(7)551-7

Influence on Behavior Beliefs and AttitudesAvorn J Chen M Hartley R Scientific versus commercial sources of influence on theprescribing behavior of physicians Am J Med 1982734-8

Caudill TS Johnson MS Rich EC McKinney WP Physicians pharmaceutical salesrepresentatives and the cost of prescribing Arch of Fam Med 19965201-206

Chew LD et al A Physician Survey of the Effect of Drug Sample Availability onPhysicians Behavior J Gen Int Med 200015 478-483

Chren MM Landefeld CS Physicians behavior and their interaction with drugcompanies JAMA 1994271684-689

Orlowski JP and Wateska L The effects of pharmaceutical firm enticements on physicianprescribing patterns Chest 1992 102270-273

Peay MY Peay ER The role of commercial sources in the adoption of a new drug SocSci Med 1988261183-9

Bias in Promotional MaterialsStryer D and Bero LA Characteristics of materials distributed by drug companies Anevaluation of appropriateness J Gen Int Med 199611575-583

Ziegler MG Lew P Singer BC The accuracy of drug information from pharmaceuticalsales representatives JAMA 19952731296-1298Comments in JAMA19952741267-1268

Wilkes MS Doblin BH Shapiro MF Pharmaceutical advertisements in leading medicaljournals expertsrsquo assessments Ann Intern Med 1992116912-9

Pharmaceutical SamplesTong KL Lien CY Do pharmaceutical representatives misuse their drug samples CanFam Physician 1995411363-1366

No Free Lunch Required Reading

httpwwwnofreelunchorgrequiredhtm (1 of 2) [2242003 215747]

Westfall JM McCabe H Nicholas RA Personal use of drug samples by physicians andoffice staff JAMA 1997278141-143 Comments in JAMA 19982791698-99

Systematic ReviewsLexchin J What information do physicians receive from pharmaceutical representativesCan Fam Phys 199743941-945

Lexchin J Interactions between physicians and the pharmaceutical industry what doesthe literature say CMAJ 1993 1491401-7

Wazana A Physicians and the Pharmaceutical Industry Is a gift ever just a gift JAMA2000 283 No 3

Commentaries essays and editorialsChren MM Landefeld S Murray TH Doctors drug companies and gifts JAMA19892623448-51

Griffith D Reasons for not seeing drug reps BMJ 1999 319 69-70

Lexchin J Doctors and detailers Therapeutic education or pharmaceutical promotionInt J Health Services 198919663-679

Shaughnessy AF and Slawson DC Pharmaceutical representatives (editorial) BMJ19963121494

Shaughnessy AF Slawson DC Bennett JH Separating the wheat from the chaffidentifying fallacies in pharmaceutical promotion J of Gen Int Med 1994 10563-8

Waud DR Pharmaceutical promotions--a free lunch N Engl J Med 1992327351-3

Wolfe SM Why do American drug companies spend more than $12 billion a yearpushing drugs Is it education or promotion J of Gen Int Med 199611 637-9

Position PapersAmerican College of Physicians-American Society of Internal Medicine Position PaperPhysician-Industry Relations Part 1 Individual Physicians Ann Intern Med2002136396-402

American College of Physicians-American Society of Internal Medicine Position PaperPhysician-Industry Relations Part 2 Organizational Issues Ann Intern Med2002136403-406

American College of Physicians Position Paper Ethics Manual 4th edition April 11998

Canadian Medical Association Policy Summary Physicians and the pharmaceuticalindustry CMAJ Feb 1 1992

Council on Ethical and Judicial Affairs American Medical Association Gifts tophysicians from industry JAMA 1991 261 501

Council on Ethical and Judicial Affairs American Medical Association Guidelines ongifts to physicians from industry an update Food and Drug Law Journal 199247445-458

Royal College of Physicians The Relationship between physicians and thepharmaceutical industry Journal of the Royal College of Physicians of London 198620(4)235-42

copy 2002 No Free Lunch



The National The National Institute for Clinical Institute for Clinical ExcellenceExcellenceNICEwwwniceukorg

Wisdom Teeth Removal

These should not be removed unless they are diseased or causing problems This means that patients will not be exposed to unnecessary risks of surgery and that

around pound5million capacity will be released

The Chief Dental Officers in both England amp Wales supported this guidance

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Welcome to NICE Technology Appraisals Appraisals in Progress ECT - Electroconvulsive Therapy 8 April 2003

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ECT - Electroconvulsive TherapyTitle The clinical effectiveness and cost effectiveness of electroconvulsive

Therapy (ECT) for depressive illness schizophrenia catatonia andmania

Scope Consultation on a draft scope took place in October 2001

Appraisal Status In progressExpected Date of Issue April 2003 Project team Technology AppraisalProject Manager

Kathleen Dalby E-mail enquiries kdnicenhsuk

Executive Lead Professor Peter LittlejohnsTechnical Lead Dr Sarah GarnerCommunications Manager Lucy Betterton E-mail enquiries LucyBettertonnicenhsuk ScheduleClosing date for invited comments on Scope 15 October 2001Information Meeting for consultees 17 January 2002Closing date for invited submissions 25 February 2002First Appraisal Committee Meeting 26 June 2002Second Appraisal Committee Meeting 24 July 2002Third Appraisal Committee Meeting 22 October 2002 Review GroupSchool of Health and Related Research University of Sheffield

Invited Stakeholders

Association of Anaesthetists of Great Britain and Ireland

Association of British Health-Care Industries

British Psychological Society

Dantec Dynamics Ltd

Department of Health

Depression Alliance

ECT Anonymous

Ectron Ltd

Health Technology Board for Scotland

Isle of Wight Portsmouth and South East Hampshire Health Authority

Long Term Medical Conditions Alliance

Manic Depression Fellowship

Mental Health Act Commission

MIND

MIND Cymru

National Schizophrenia Fellowship

Royal College of Anaethetists

Royal College of Nursing

Royal College of Psychiatrists

SANE

ECT - Electroconvulsive Therapy - NICE

httpwwwniceorgukcataspc=20218 (1 of 3) [842003 094627]

Sigurethur Helgason

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Bi-polar disorder - new drugsTitle The clinical effectiveness and cost effectiveness of new drugs for

bi-polar disorder This page contains information on key dates contacts and consultees for the above appraisal Asdocuments relating to this appraisal eg the Scope press releases Appraisal ConsultationDocument and Final Appraisal Determination are produced they will be published on the websiteLinks to these documents can be found at the bottom of the page As this page is updated a shorthistory will be created in the Project History section below Scope Consultation on a draft scope took place in May 2002

Status In progressExpected Date of Issue July 2003 Project team Technology AppraisalsProject Manager


Executive Lead Andrea SutcliffeTechnical Lead Dr Sarah GarnerCommunications Manager Lucy Betterton Email enquiries LucyBettertonnicenhsuk ScheduleClosing date for invited comments on draftscope

30 May 2002

Final scope published June 2002Information Meeting for consultees 15 August 2002Closing date for invited submissions 21 October 2002First Appraisal Committee Meeting 25 February 2003Second Appraisal Committee Meeting 24 April 2003 Review GroupNHS Centre for Reviews and Dissemination University of York

Invited ConsulteesAstraZeneca

British Association for Psychopharmacology

Cambridge City PCT


Eli Lilly


Institute of Psychiatry



Marceacute Society

Mental After Care Association

Mental Health Foundation

Mentality

MIND

MIND Cymru

National Collaborating Centre for Mental Health

Bi-polar disorder - new drugs - NICE


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Welcome to NICE Clinical Guidelines Guidelines and cancer service guidance in progress Eating disorders 18 April 2003

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Eating disordersFull title Eating disorders the management of anorexia nervosa bulimia nervosa and binge eating disorders

The full scope for this Guideline can be found at the bottom of the page when finalised

Status In progressExpected date of issue January 2004

Lead Collaborating Centre The National Collaborating Centre for MentalHealth

Contact person Catherine Pettinari

Email Catherinepettinarivirginnet

NICE project team Guidelines Coordinator Elaine Paton

Email enquiries eatingdisordersnicenhsuk

Guidelines Commissioning Manager Christine Sealey

Executive Lead Andrea Sutcliffe

Communications Manager Phil Ranson

Email enquiries PhilipRansonnicenhsuk

Provisional schedule Consultation on draft scope bystakeholders

May-June 2001

Meeting with patientcarerstakeholder organisations

July 2001

Final scope posted on website November 2001 First Guideline Development Groupmeeting

March 2002

Submission of evidence bystakeholders

May 2002

Consultation on first draft ofguideline by stakeholders

June 2003

Consultation on final draft ofguideline

August 2003

Expected date of issue January 2004

Guideline Development GroupThe Guideline Development Group (GDG) oversees the development process

Stakeholders

Eating disorders - NICE


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Welcome to NICE Clinical Guidelines Guidelines and cancer service guidance in progress Self Harm 18 April 2003

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Self HarmFull title Self harm the short-term physical and psychological management and secondary preventionof self harm in primary and secondary care


Status In ProgressExpected date of issue March 2004

Lead Collaborating Centre The National Collaborating Centre for MentalHealth is leading this work

Contact person Rebecca King

Email rebeccakingvirginnet

NICE project team

Guidelines Coordinator Elaine Paton

Email enquiries selfharmnicenhsuk



Communications Manager Lucy Betterton

Email enquiries LucyBettertonnicenhsuk


8 February - 8 March 2002


March 2002

Final scope posted on website May 2002 First Guideline Development Groupmeeting

May 2002


TBC


September 2003


November 2003

Expected date of issue March 2004


Stakeholders

Self Harm - NICE


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Obsessive compulsive disorder (OCD)Full title Anxiety Management of obsessive compulsive disorder in adults in primary secondary andcommunity care


Status NewExpected date of issue February 2005



Email catherinepettinarivirginnet


Email enquiries ocdptsdnicenhsuk

Guidelines Commissioning Manager Chirstine Sealey

Executive Lead Andrew Dillon



Provisional schedule Consultation on draft anxiety scopeby stakeholders

27 November ndash 3 January 2002


4 March 2002

Final scope posted on website February 2003 First Guideline Development Groupmeeting

March 2003


TBC


July 2004


October 2004

Expected date of issue February 2005

The Editorial BoardThe Guideline Development Group (GDG) oversees the development process

Obsessive compulsive disorder (OCD) - NICE


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Post-traumatic Stress Disorder (PTSD)Full title Anxiety Management of post-traumatic stress disorder in adults in primary secondary andcommunity care


Status In ProgressExpected date of issue January 2005











27 November - January 2002


4 March 2002

Final scope posted on website April 2003 First Guideline Development Groupmeeting

February 2003


FebruaryMarch 2003


June 2004


August 2004


Guideline Development Group (GDG)The Guideline Development Group (GDG) oversees the development process

Post-traumatic Stress Disorder (PTSD) - NICE


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Welcome to NICE Clinical Guidelines Guidelines and cancer service guidance in progress Depression in children 18 April 2003

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Depression in childrenFull title Depression in children identification and management of depression in children and young peoplein primary care and specialist services


Status In progressExpected date of issue March 2005


Contact person Michelle Clark

Email michelleclarkuclacuk

NICE project team


Email enquiries depressioninchildrennicenhsuk

Guidelines Commissioning Manager Chris Sealey





28th November - 9th January 2003


10th December 2002


February 2003


TBC


August 2004


December - January 2004



Stakeholders

Depression in children - NICE


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Welcome to NICE Clinical Guidelines Completed guidelines and cancer service guidance Schizophrenia core interventions in the treatment and management of schizophrenia in primary and secondary care18 April 2003

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Schizophrenia core interventions in the treatmentand management of schizophrenia in primary andsecondary care

The National Institute for Clinical Excellence has issued its first fully commissioned clinical guideline on theappropriate treatment and care of individuals with schizophrenia within the NHS in England and WalesNICE clinical guidelines ensure that no matter where people live in England and Wales they can beconfident that the health professionals caring for them are working to high-quality evidence based nationalstandards

2003008 NICE welcomes full schizophrenia guideline and training programme

25 March 2003

The National Institute for Clinical Excellence (NICE or the Institute) has today (25 March 2003)welcomed the publication of the full schizophrenia guideline by the National Collaborating Centre forMental Health (NCCMH)

In addition the Institute supports the launch of a new training package that will enable healthcareprofessionals to familiarise themselves with the schizophrenia guideline in an interactive trainingprogramme

Schizophrenia guideline training website

25 March 2003

The National Collaborating Centre for Mental Health has developed a training website for healthprofessionals that gives information on how to understand and use the NICE schizophrenia guidelinewhat the guideline is and how it was developed and the basic concepts underlying the evidence-basedguideline

Click on the link above to access the website (please note this will take you to the Royal College ofPsychiatrists website)

2002062 First clinical guideline from NICE sets out recommendations for NHS care in schizophrenia

4 December 2002

The National Institute for Clinical Excellence has issued its first fully commissioned clinical guidelineon the appropriate treatment and care of individuals with schizophrenia within the NHS in England andWales NICE clinical guidelines ensure that no matter where people live in England and Wales they canbe confident that the health professionals caring for them are working to high-quality evidence basednational standards

Media Briefing - Clinical guideline on Schizophrenia

4 December 2002

Schizophrenia core interventions in the treatment and management of schizophrenia in primary andsecondary care (NICE guideline)

4 December 2002

This is the NICE guideline that has been issued as guidance to the NHS in England and Wales

Schizophrenia core interventions in the treatment and management of schizophrenia in primary and secondary care - NICE


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Appraisals in ProgressAll the technology appraisals currently in development are listed below Click on a title to go to a summarysheet showing key dates the project history contact details and a list of the consultees for the appraisal

The list can be sorted by title (alphabetically) wave number or anticipated publication date - simply clickon the relevant column heading in the blue box once or twice depending on whether you want an ascendingor descending list For more information on using the list and the terms and abbreviations click here

Title Wave AnticipatedPublication

Date

Alzheimers disease - memantine (Ebixa) 8 TBC

Asthma (uncontrolled) - Omalizumab (Xolair) 8 TBC

Atopic dermatitis (eczema) - Pimecrolimus (Elidel) and tacrolimus(Protopic)

8 TBC

Atopic dermatitis (eczema) - topical steroids 8 TBC

Bi-polar disorder - new drugs 6 July 2003

Breast cancer (early) - hormonal treatments 8 TBC

Breast Cancer - capecitabine 6 May 2003

Colorectal cancer - capecitabine and tegafur uracil 6 May 2003

Conduct disorder parent training programmes for treatment andprevention

8 TBC

Coronary events - statins 8 TBC

Coronary Imaging - myocardial perfusion scintigraphy in the diagnosis andmanagement of cardiac disease

7 November 2003

Dementia (non-Alzheimer) - New pharmaceutical treatments 8 TBC

Diabetes (Type 2) - Glitazones (review) R April 2003

Diabetes - patient education models 6 May 2003

Diabetic foot ulcers - new treatments 8 TBC

Dual chamber pacing 8 TBC

Dyspepsia - Proton pump inhibitors (PPIs) (review) R May 2004

ECT - Electroconvulsive Therapy 6 April 2003

Epilepsy in adults - newer drugs 6 October 2003

Epilepsy in children - newer drugs 6 October 2003

Flu - (prophylaxis) amantadine and oseltamivir 6 October 2003

Gastro-intestinal stromal tumours - imatinib (Glivec) 8 TBC

Heart disease - drug eluting stents for the prevention of restenosis andreview of coronary artery stents

7 August 2003

Hepatitis C - pegylated interferons ribavarin and alfa interferon 7 November 2003

Appraisals in Progress - NICE


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Sigurethur Helgason
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Osteosarcoma






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ColorectalCancer

LungCancer

MultipleMyeloma

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OvarianCancer

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of 2Valproate for acute mood episodes in bipolar disorder (Cochrane Review)


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HTA - Guidelines

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COPD

aethrir vefir

laeligknablaeth


SIGN

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form1

x

f9 Go

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f3 GO

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form1

x

f1 Leitaroreth

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form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

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kaeligrur


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vinnslu


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Endurtaka

lt 56 (61) 56-60 (61-69) 2 gildi ge 61 (70)

Sykursyacuteki































wwwnzggorgnz

librarycfm






































Jaacute

Nei



























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referenceguide

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(225K) (974K)

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Sigurethur Helgason

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13




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n D

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no

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y A

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rais

al G

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ance

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o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

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SystemicTreatment




PracticeGuidelines











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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1






vinnslu


Eyethubloumleth

Aethrir vefir

English














Houmlfundar


Yfirlit


Lykiloreth


Almennt


Fraeligethigreinar


Inngangur





Tafla I

Tafla II

Tafla III

Tafla IV

Tafla V













Endurtaka

lt 56 (61) 56-60 (61-69) 2 gildi ge 61 (70)

Sykursyacuteki































wwwnzggorgnz

librarycfm






































Jaacute

Nei



























Endurmat














NEI

NEI

JAacute

JAacute


































Houmlfundar

Almennt












Aethrir vefir

Aethrir vefir



























SEARCH NICE

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Cymraeg

Vision Impaired

Email notify

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Date Review

Date
































Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

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Dantec Dynamics Ltd


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SANE



Sigurethur Helgason

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30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



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MIND Cymru




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March 2002


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4 March 2002


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4 March 2002


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10th December 2002


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25 March 2003




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Using this Site

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Cymraeg

Vision Impaired

Email notify

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1



Houmlfundar


Yfirlit


Lykiloreth


Almennt


Fraeligethigreinar


Inngangur





Tafla I

Tafla II

Tafla III

Tafla IV

Tafla V













Endurtaka

lt 56 (61) 56-60 (61-69) 2 gildi ge 61 (70)

Sykursyacuteki































wwwnzggorgnz

librarycfm






































Jaacute

Nei



























Endurmat














NEI

NEI

JAacute

JAacute


































Houmlfundar

Almennt












Aethrir vefir

Aethrir vefir



























SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

Publications

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Conference

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Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date Review

Date
































Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy











Dantec Dynamics Ltd


Depression Alliance

ECT Anonymous

Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

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f1 ssserver_siteini

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f3 GO

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f1 Leitaroreth

f2


form1

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f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

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f7 simple

f6 19915

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form1

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f6 20079

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form1

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Endurtaka

lt 56 (61) 56-60 (61-69) 2 gildi ge 61 (70)

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librarycfm






































Jaacute

Nei



























Endurmat














NEI

NEI

JAacute

JAacute


































Houmlfundar

Almennt












Aethrir vefir

Aethrir vefir



























SEARCH NICE

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Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




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Protocols


























Search


About

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ABSTRACT

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332920



4 2 and 3 377

5 1 and 4 104






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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1



































Jaacute

Nei



























Endurmat














NEI

NEI

JAacute

JAacute


































Houmlfundar

Almennt












Aethrir vefir

Aethrir vefir



























SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Date Review

Date
































Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

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Dantec Dynamics Ltd


Depression Alliance

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Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

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About NICE


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30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

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MIND Cymru




SEARCH NICE

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March 2002


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4 March 2002


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4 March 2002


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FebruaryMarch 2003


June 2004


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SEARCH NICE

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10th December 2002


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25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

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Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1















Endurmat














NEI

NEI

JAacute

JAacute


































Houmlfundar

Almennt












Aethrir vefir

Aethrir vefir



























SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

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Conference

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Links

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Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date Review

Date
































Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy











Dantec Dynamics Ltd


Depression Alliance

ECT Anonymous

Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

Advancedraquo


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About NICE


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Vision Impaired

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30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

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MIND Cymru




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May-June 2001


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Stakeholders



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NICE project team










March 2002


May 2002


TBC


September 2003


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Self Harm - NICE


SEARCH NICE

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4 March 2002


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4 March 2002


February 2003


FebruaryMarch 2003


June 2004


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HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


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COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

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CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1






























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referenceguide

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Sigurethur Helgason

131313

13131313

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13




Medicine



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n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

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SystemicTreatment




PracticeGuidelines











ColorectalCancer

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1





Aethrir vefir

Aethrir vefir



























SEARCH NICE

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Date Review

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Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

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Dantec Dynamics Ltd


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MIND Cymru





SANE



Sigurethur Helgason

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30 May 2002




Cambridge City PCT


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Marceacute Society



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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1





















SEARCH NICE

Advancedraquo


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About NICE


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Cymraeg

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Email notify

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Date Review

Date
































Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


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Press Office

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Job Vacancies

Links

News Archive

Using this Site

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Cymraeg

Vision Impaired

Email notify

Privacy











Dantec Dynamics Ltd


Depression Alliance

ECT Anonymous

Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

Advancedraquo


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About NICE


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Cymraeg

Vision Impaired

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30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

MIND

MIND Cymru




SEARCH NICE

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March 2002


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4 March 2002


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25 March 2003




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SEARCH NICE

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Using this Site

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Cymraeg

Vision Impaired

Email notify

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1



Houmlfundar

Yfirlit


Almennt













referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


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June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

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SOR













See also Italian





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Search


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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1




referenceguide

Fullguideline

PublicationDate


February2003



January 2003

64



2002


January 2003


October 2002


September2002


June 2002


June 2002


February2002


January 2002


(225K) (974K)

January 2002


November2001



Sigurethur Helgason

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

131313

13131313

13

13




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

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Dantec Dynamics Ltd


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30 May 2002




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25 March 2003




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Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1




Medicine



Respiratory Society


Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

Advancedraquo


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Dantec Dynamics Ltd


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MIND Cymru





SANE



Sigurethur Helgason

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30 May 2002




Cambridge City PCT


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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

Cya

n D

ON

O








wwwniceorguk







Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




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Protocols


























Search


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ABSTRACT

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332920



4 2 and 3 377

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gfedc gfedc




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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1


Tech

no

log

y A

pp

rais

al G

uid

ance

- N

o2

4

April 2001






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


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Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1






AUGUST 2002


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Links

News Archive

Using this Site

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Cymraeg

Vision Impaired

Email notify

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Dantec Dynamics Ltd


Depression Alliance

ECT Anonymous

Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

Advancedraquo


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About NICE


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Using this Site

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Cymraeg

Vision Impaired

Email notify

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30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

MIND

MIND Cymru




SEARCH NICE

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March 2002


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4 March 2002


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NICE project team










10th December 2002


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August 2004





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25 March 2003




25 March 2003




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4 December 2002


4 December 2002




SEARCH NICE

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Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1


Technology Report

Issue 34 March 2003

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy











Dantec Dynamics Ltd


Depression Alliance

ECT Anonymous

Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

Publications

Press Office

Conference

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Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

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30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

MIND

MIND Cymru




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

v


Sigurethur Helgason
Sigurethur Helgason
Sigurethur Helgason



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














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SOR













See also Italian





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Protocols


























Search


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ABSTRACT

Order full review



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Limit to


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332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1



Houmlfundar


Yfirlit


Almennt




Aethdragandinn
















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

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Dantec Dynamics Ltd


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MIND

MIND Cymru





SANE



Sigurethur Helgason

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30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

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4 March 2002


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4 March 2002


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NICE project team










10th December 2002


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25 March 2003




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4 December 2002


4 December 2002




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Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1















Osteosarcoma






GenitourinaryCancer

GynecologicalCancer

Head andNeckCancer






























SystemicTreatment




PracticeGuidelines











ColorectalCancer

LungCancer

MultipleMyeloma

TumorMarkers



SOR





















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

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About NICE


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Links

News Archive

Using this Site

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Cymraeg

Vision Impaired

Email notify

Privacy











Dantec Dynamics Ltd


Depression Alliance

ECT Anonymous

Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

Publications

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Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy






30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

MIND

MIND Cymru




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Using this Site

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May-June 2001


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March 2002


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4 March 2002


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4 March 2002


February 2003


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June 2004


August 2004





SEARCH NICE

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Using this Site

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Cymraeg

Vision Impaired

Email notify

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NICE project team










10th December 2002


February 2003


TBC


August 2004





Stakeholders



SEARCH NICE

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Using this Site

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Cymraeg

Vision Impaired

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25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1




















ColorectalCancer














OvarianCancer

PancreaticCancer






SOR













See also Italian





Library



Search abstracts




Reviews
































Protocols


























Search


About

Log on

Whats in


How to get access



Document Delivery

Feedback




The Cancer Library

Acluster


Meerkat



























ABSTRACT

Order full review



Search abstracts

















Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




gfedc

gfedc











ABSTRACT

Order full review



Search abstracts






whats new

facts amp fallacies

required reading

medical students

things you can do

take the pledge

pen amnesty

paraphernalia


join or contribute

comments

about us















































SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy











Dantec Dynamics Ltd


Depression Alliance

ECT Anonymous

Ectron Ltd






MIND

MIND Cymru





SANE



Sigurethur Helgason

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy






30 May 2002




Cambridge City PCT


Eli Lilly





Marceacute Society



Mentality

MIND

MIND Cymru




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

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Links

News Archive

Using this Site

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Cymraeg

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f9 Go

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f6 20079

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aethrir vefir

laeligknablaeth


SIGN

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HTA leit

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form1

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f9 Go

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f3 GO

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form1

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f6 20079

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f6 42424

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8 TBC







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7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1


Search


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gfedc gfedc




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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1













ABSTRACT

Order full review



Search abstracts

















Limit to


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Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






gfedc gfedc




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gfedc











ABSTRACT

Order full review



Search abstracts






whats new

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

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f6 19915

f10


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x

f6 20079

f7 simple

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f9 Go

f10


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f6 20115

f7 simple

f8

f9 Go

f10


form1

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f6 33922

f7 simple

f8

f9 Go

f10


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x

f6 57890

f7 simple

f8

f9 Go

f10


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x

f6 33920

f7 simple

f8

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f10


form1

x

f6 42424

f7 simple

f8

f9 Go

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f1 Leitaroreth

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form1

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f1 Leitaroreth

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form2

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f1 [Hraethval]

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f1












Limit to


bull


bull

Pre-MEDLINE MEDLINE



332920



4 2 and 3 377

5 1 and 4 104






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gfedc

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ABSTRACT

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1









ABSTRACT

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

whats new

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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1



























SEARCH NICE

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30 May 2002




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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

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10th December 2002


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TBC


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25 March 2003




25 March 2003




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4 December 2002


4 December 2002




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Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

SEARCH NICE

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May-June 2001


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June 2003


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Cymraeg

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NICE project team










March 2002


May 2002


TBC


September 2003


November 2003



Stakeholders

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4 March 2002


March 2003


TBC


July 2004


October 2004





SEARCH NICE

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Cymraeg

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4 March 2002


February 2003


FebruaryMarch 2003


June 2004


August 2004





SEARCH NICE

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Using this Site

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Cymraeg

Vision Impaired

Email notify

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NICE project team










10th December 2002


February 2003


TBC


August 2004





Stakeholders



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25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

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Using this Site

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Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

SEARCH NICE

Advancedraquo


E-newsletter

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NICE project team










March 2002


May 2002


TBC


September 2003


November 2003



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Using this Site

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Cymraeg

Vision Impaired

Email notify

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4 March 2002


March 2003


TBC


July 2004


October 2004





SEARCH NICE

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E-newsletter

About NICE


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Using this Site

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Cymraeg

Vision Impaired

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4 March 2002


February 2003


FebruaryMarch 2003


June 2004


August 2004





SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy







NICE project team










10th December 2002


February 2003


TBC


August 2004





Stakeholders



SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Using this Site

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Cymraeg

Vision Impaired

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25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Clinical Audit

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News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Cymraeg

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4 March 2002


March 2003


TBC


July 2004


October 2004





SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Using this Site

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Cymraeg

Vision Impaired

Email notify

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4 March 2002


February 2003


FebruaryMarch 2003


June 2004


August 2004





SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


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Publications

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Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy







NICE project team










10th December 2002


February 2003


TBC


August 2004





Stakeholders



SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Using this Site

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Cymraeg

Vision Impaired

Email notify

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25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


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Clinical Audit

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Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

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Conference

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Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy
















4 March 2002


February 2003


FebruaryMarch 2003


June 2004


August 2004





SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

Publications

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Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy







NICE project team










10th December 2002


February 2003


TBC


August 2004





Stakeholders



SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


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News Archive

Using this Site

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Cymraeg

Vision Impaired

Email notify

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25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy







NICE project team










10th December 2002


February 2003


TBC


August 2004





Stakeholders



SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

form3

x

f1

SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

Board Meetings


Citizens Council

Publications

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Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




25 March 2003




25 March 2003




4 December 2002



4 December 2002


4 December 2002




SEARCH NICE

Advancedraquo


E-newsletter

About NICE


Clinical Guidelines


Clinical Audit

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Citizens Council

Publications

Press Office

Conference

Job Vacancies

Links

News Archive

Using this Site

English

Cymraeg

Vision Impaired

Email notify

Privacy




Date




8 TBC







8 TBC



7 November 2003













7 August 2003























HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

f2


form1

x

f1 Leitaroreth

f2


form2

x

f1 [Hraethval]

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SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


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HTA - Guidelines

LL index KL

vinnuhoacutepar

CIOP

DM II

x Ray


anaphylax

COPD

aethrir vefir

laeligknablaeth


SIGN

SIGN depr

SIGN BTS asthma

SIGN hip fract

SBU dvt

NZGG card rehab

CPG HTA

KM onc index

suzuki

methodology

levels of evidence



valproate bipolar


nofreelunchorg

NICE

nice guide

wisdom

vinnulag

why CPG

HTA leit

NICEpdf


form1

x

f9 Go

f8

f7 simple

f6 153

f10


form1

x

f1 ssserver_siteini

f2

f3 GO

f4


form1

x

f1 Leitaroreth

f2


form1

x

f9 Go

f8

f7 simple

f6 17935

f10


form1

x

f9 Go

f8

f7 simple

f6 20218

f10


form1

x

f9 Go

f8

f7 simple

f6 19915

f10


form1

x

f6 20079

f7 simple

f8

f9 Go

f10


form1

x

f6 20115

f7 simple

f8

f9 Go

f10


form1

x

f6 33922

f7 simple

f8

f9 Go

f10


form1

x

f6 57890

f7 simple

f8

f9 Go

f10


form1

x

f6 33920

f7 simple

f8

f9 Go

f10


form1

x

f6 42424

f7 simple

f8

f9 Go

f10


form1

x

f1 Leitaroreth

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form1

x

f1 Leitaroreth

f2


form2

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f1 [Hraethval]

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fsa 28 feb 2003 - landlaeknir.is · sykursýki af tegund tvö 832 lÆknablaÐiÐ2002/88...

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