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Functional interactions between large-scale networks during memory search

Supplementary Materials

James E. Kragel1,2, & Sean M. Polyn1

1Department of Psychology, Vanderbilt University, Nashville, TN 37240, 2Neuroscience GraduateProgram, Vanderbilt University, Nashville, TN

Supplementary Materials 1

*

*

Rt Sp Rs−8−6−4−2

02468

101214

β (a

u)

PM/IC6

PC/IC23

MP/IC26

PC/IC23

+ MP/IC26

PC/IC23

+ PM/IC6

PC/IC23

+ MP/IC26

+ PM/IC6

vmPFC

mPFC mPFC

vmPFC

SPL

SPL

RSC

AGL

AGR

SPL

RSC

HF

IFGSMG

SFG

**

Rt Sp Rs−8−6−4−2

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β (a

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SFG

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Rt Sp Rs−8−6−4−2

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β (a

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IFG

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Rt Sp Rs−8−6−4−2

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β (a

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RSC

*

*

Rt Sp Rs−8−6−4−2

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β (a

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vmPFC

HF

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Rt Sp Rs−8−6−4−2

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β (a

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mPFC

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Rt Sp Rs−8−6−4−2

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β (a

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AGL

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β (a

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RSC

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Rt Sp Rs−8−6−4−2

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β (a

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vmPFC

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β (a

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SPL

Supplementary Figure 1. Individual regions of interest within the DMN exhibit memory searchrelated activity. Center panel depicts a surface projection of all ROIs constructed from PM/IC6,PC/IC23, and MP/IC26 in green, red, and blue respectively. Overlap of ROIs is depicted by logicaladdition of their respective colors. Regions exhibited significant (p < 0.05, Bonferroni-corrected formultiple comparisons across all 53 ROIs) effects are marked with an asterisk, including transientrecall related (Rt), speech related (Sp), and sustained recall related (Rs). A horizontal bar denotesa significant differences between transient, recall related activity and the speech control task.vmPFC, ventromedial prefrontal cortex; IFG, inferior frontal gyrus; SFG, superior frontal gyrus;AGL, left angular gyrus; RSC, retrosplenial cortex; mPFC, medial prefrontal cortex; SPL, superiorparietal lobule; HF, hippocampal formation. au, arbitrary units.


RFP/IC14

DFP/IC7

DFP/IC7 + RFP/IC

14

IPSPPC

SFGR

rPFC

PFCL

PFCR

HF

SMG

SFGL

SPL

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Rt Sp Rs−8−6−4−2

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β (a

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SFGR

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β (a

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rPFC

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β (a

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PFCL

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β (a

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SPL

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Rt Sp Rs−8−6−4−2

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β (a

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SMG

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β (a

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IPS

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β (a

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PPC

**

Rt Sp Rs−8−6−4−2

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β (a

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HF

*

Rt Sp Rs−8−6−4−2

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β (a

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SFGL

**

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Rt Sp Rs−8−6−4−2

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β (a

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PFCR

Supplementary Figure 2. Individual regions of interest within the DAN exhibit memory searchrelated activity. Center panel depicts a surface projection of all ROIs constructed from DFP/IC7,and RFP/IC14 in blue and red respectively. Overlap of ROIs is depicted by logical addition oftheir respective colors. Regions exhibited significant (p < 0.05, Bonferroni-corrected for multiplecomparisons across all 53 ROIs) effects are marked with an asterisk, including transient recallrelated (Rt), speech related (Sp), and sustained recall related (Rs). A horizontal bar denotes asignificant differences between transient, recall related activity and the speech control task. SFGR,right superior frontal gyrus; SPL, superior parietal lobule; PPC, posterior parietal cortex; PFCR,right prefrontal cortex; HF, hippocampal formation; rPFC, rostrolateral prefrontal cortex; IPS,intraparietal sulcus; SMG, supramarginal gyrus; SFGL, left superior frontal gyrus; PFCL, leftprefrontal cortex.


SM/IC24

TI/IC12

CER/IC13

TI/IC12

+ SM/IC24

IFGR

rPFCR

rPFCL

PreCuR

IFGL

HF

PreCuL

SFG

*

Rt Sp Rs−8−6−4−2

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β (a

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rPFCL

*

Rt Sp Rs−8−6−4−2

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β (a

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rPFCR

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Rt Sp Rs−8−6−4−2

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β (a

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IFGR

*

Rt Sp Rs−8−6−4−2

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β (a

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IFGL

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Rt Sp Rs−8−6−4−2

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β (a

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PreCuR

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Rt Sp Rs−8−6−4−2

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β (a

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HF

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Rt Sp Rs−8−6−4−2

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β (a

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PreCuL

*

Rt Sp Rs−8−6−4−2

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β (a

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SFG

Supplementary Figure 3. Regions of interest constructed from large-scale functional networksexhibit search related activity. Center panel depicts a surface projection of all ROIs constructedfrom SM/IC24, TI/IC12, and CER/IC13 in green, red, and blue respectively. Overlap of ROIs isdepicted by logical addition of their respective colors. Regions exhibited significant (p < 0.05,Bonferroni-corrected for multiple comparisons across all 53 ROIs) effects are marked with anasterisk, including transient recall related (Rt), speech related (Sp), and sustained recall related(Rs). A horizontal bar denotes a significant differences between transient, recall related activityand the speech control task. SFG, superior frontal gyrus; rPFCR, right rostrolateral prefrontalcortex; IFGR, right inferior frontal gyrus; PreCuR, right precuneus; HF, hippocampal formation;rPFCL, left rostrolateral prefrontal cortex; IFGL, left inferior frontal gyrus; PreCuL, left precuneus.


VP/IC20

*

Rt Sp Rs−8−6−4−2

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vmPFC

vmPFC

Supplementary Figure 4. Regions of interest constructed from large-scale functional networksexhibit search related activity. Center panel depicts a surface projection of all ROIs constructedfrom VP/IC20 in red. Regions exhibited significant (p < 0.05, Bonferroni-corrected for multiplecomparisons across all 53 ROIs) effects are marked with an asterisk, including transient recallrelated (Rt), speech related (Sp), and sustained recall related (Rs). vmPFC, ventromedial prefrontalcortex.


Supplementary Table 1. Recall-driven effects in component derived regions of interest.

Network Region extent (voxels) x,y,z (mm) tRs tRt tRt−Sp

PM/IC6 Hippocampus (R) 178 21,-34,-5 -2.8 4.25 4.23

Precuneus (L) 260 -9,-58,16 -2.86 3.19 5.33

Supramarginal Gyrus (R) 60 57,-22,43 -3 1.75 1.69

Anterior Cingulate (L) 27 -3,8,31 -4.58 3.7 3.72

Middle Frontal Gyrus pars Orbitalis (R) 284 6,65,-8 -5.53 3.36 4.54

Inferior Frontal Gyrus pars Orbitalis (R) 33 30,29,-8 -2.16 1.86 2.02

Inferior Frontal Gyrus pars Triangularis (R) 99 42,29,7 -1.97 2.75 3.1

Inferior Frontal Gyrus pars Opercularis (R) 75 42,11,25 -5.07 2.71 4.25

Superior Frontal Gyrus (R) 24 18,32,37 -1.76 3.49 3.84

Superior Frontal Gyrus (R) 147 24,8,52 -5.41 2.48 4.08

DFP/IC7 Parahippocampal Gyrus (R) 41 21,5,-20 -4.29 5.10 4.58

Amygdala (L) 25 -18,2,-20 -2.93 4.67 3.63

Precuneus (R) 1852 -3,-76,52 -6.68 3.74 4.88

Inferior Parietal Lobule (L) 73 -57,-34,43 -4.15 2.53 1.84

Middle Frontal Gyrus pars Orbitalis (L) 138 -27,32,-20 -1.68 0.55 0.80

Superior Frontal Gyrus pars Orbitalis (R) 92 18,14,-20 -2.29 1.04 1.78

Superior Frontal Gyrus (L) 921 -24,38,34 -6.44 3.21 3.73

Middle Frontal Gyrus (R) 340 30,38,25 -3.99 3.65 4.22

Middle Frontal Gyrus (R) 129 36,-4,55 -5.52 3.17 4.80

TI/IC12 Hippocampus (R) 151 33,-16,-8 -2.24 4.11 4.05

Hippocampus (L) 128 -33,-10,-11 -2.52 3.73 3.48

Supramarginal Gyrus (L) 173 -54,-31,25 -3.92 3.38 2.7

Supramarginal Gyrus (R) 247 51,-31,25 -3.34 2.81 2

Precuneus (R) 49 12,-64,25 -3.01 4.67 6.76

Anterior Cingulate (R) 304 3,35,1 -2.44 3.55 3.75


Middle Frontal Gyrus pars Orbitalis (L) 336 -36,47,-5 -3.88 4.15 3.56


CER/IC13 Middle Frontal Gyrus (L) 125 -30,50,31 -5.75 2.71 3.26


RFP/IC14 Hippocampus (R) 67 15,-31,-2 -2.29 5.09 6.01

Parahippocampal Gyrus (R) 27 24,11,-23 -4.67 3.31 4.09

Precuneus (R) 43 12,-58,25 -4.57 3.67 5.1

Inferior Parietal Lobule (R) 955 51,-52,43 -4.88 2.75 4.11

Inferior Parietal Lobule (L) 199 -48,-40,49 -6.36 1.81 3.1

Middle Frontal Gyrus (L) 32 -30,17,46 -2.97 3.1 4.4


VP/IC20 Middle Frontal Gyrus pars Orbitalis (R) 887 3,32,-11 -2.37 2.21 3.32



PC/IC23 Precuneus (R) 2575 15,-64,25 -5.92 3.9 5.72

Anterior Cingulate (L) 390 0,41,1 -3.22 3.66 4.15

SM/IC24 Superior Frontal Gyrus pars Orbitalis (R) 24 9,47,-23 -3.42 0.372 1.38

Inferior Frontal Gyrus pars Opercularis (L) 21 -60,8,16 -1.92 3.94 4.28



Middle Frontal Gyrus (L) 66 -30,20,40 -2.87 2.98 3.4

MP/IC26 Parahippocampal Gyrus (R) 38 24,-25,-20 -2.31 1.88 2.14

Inferior Frontal Gyrus pars Orbitalis (L) 48 -33,17,-23 -2.76 2.81 2.64

Posterior Cingulate (L) 286 -3,-55,28 -3.46 3.3 4.74

Angular Gyrus (L) 258 -51,-67,31 -4.1 3.76 3.76

Angular Gyrus (R) 184 54,-61,34 -3.5 2.72 3.28

Medial Superior Frontal Gyrus (R) 3552 3,56,22 -4.48 3.78 4.36

Note: Emphasized t-values indicate p < 0.05, Bonferroni corrected. Coordinates are reported in

Talairach space. R, right; L, left. Transient recall-related, sustained recall-related, and speech-

related effects are denoted by Rt, Rs, and Sp, respectively.


Supplementary Table 2. Spatial loadings of recall-related functional networks identified with

independent component analysis.

Network Region BA extent peak coordinate (mm) t

PM/IC6 – positive Posterior Cingulate (R) 30 2349 9,-53,8 32.97

Posterior Cingulate (L) 30 -9,-56,10 29.33

Inferior Frontal Gyrus (R) 9 34,6,27 16.84

Culmen (L) -20,-40,-12 14.35

Lentiform Nucleus (R) 32,-14,4 14.27

Postcentral Gyrus (R) 2 48,-23,41 13.91

Fusiform Gyrus (R) 37 26,-40,-11 11.90

Insula (R) 13 37,24,16 11.36

Claustrum (R) 24,25,-0 10.23

Sub-Gyral (R) 6 748 20,1,51 18.72

Cingulate Gyrus (L) 32 -15,5,40 17.47

Cingulate Gyrus (R) 24 1,-3,42 12.26

Medial Frontal Gyrus (R) 10 317 4,59,2 13.77

Superior Temporal Gyrus (R) 38 47 35,22,-27 9.93

Middle Temporal Gyrus (L) 19 60 -37,-80,18 9.31

Pyramis (L) 21 -28,-78,-32 9.17

Medial Frontal Gyrus (R) 8 23 15,27,40 7.97

PM/IC6 – negative Superior Temporal Gyrus (L) 39 1225 -46,-55,31 25.19

Precuneus (L) 31 -15,-53,32 14.84

Cingulate Gyrus (L) 23 -1,-19,33 13.16


Middle Temporal Gyrus (L) 21 786 -50,-32,-6 21.52

Inferior Parietal Lobule (R) 40 480 48,-51,41 21.07

Superior Temporal Gyrus (R) 22 557 43,-33,-2 19.47

Middle Temporal Gyrus (R) 20 60,-43,-8 8.55

Caudate (R) 38,-12,-11 7.94


Superior Frontal Gyrus (R) 6 1067 9,19,61 14.43

Superior Frontal Gyrus (L) 8 -32,23,52 13.87

Superior Frontal Gyrus (R) 9 23,47,34 12.77


Middle Frontal Gyrus (R) 8 43,27,38 10.69

Middle Frontal Gyrus (L) 10 -28,45,3 10.42



Precentral Gyrus (L) 6 -46,-1,50 9.10

Fastigium (R) 461 7,-59,-21 13.43

Tuber (R) 29,-59,-26 10.00

Declive (L) -12,-63,-11 9.18

Insula (R) 13 90 43,6,-1 12.72

Caudate (L) 140 -11,18,-6 11.73

Parahippocampal Gyrus (L) 34 -14,-3,-17 8.80

Postcentral Gyrus (L) 3 73 -7,-34,69 11.30

Cuneus (R) 18 29 15,-77,14 8.92

Middle Occipital Gyrus (R) 18 20 40,-77,-9 8.79

Cuneus (L) 18 20 -6,-85,10 8.07

DFP/IC7 – positive Precuneus (L) 7 2358 -4,-77,43 28.20

Superior Parietal Lobule (L) 7 -10,-61,53 22.26

Superior Parietal Lobule (R) 7 9,-63,53 17.42

Superior Parietal Lobule (R) 7 31,-49,52 14.73

Precuneus (L) 7 -4,-46,43 13.61

Inferior Parietal Lobule (R) 40 31,-34,37 13.51




Cingulate Gyrus (R) 31 6,-28,37 8.96


Middle Frontal Gyrus (L) 8 1296 -23,30,37 19.73



Anterior Cingulate (L) 32 -20,27,12 10.15

Medial Frontal Gyrus (L) 6 -18,6,51 9.12

Parahippocampal Gyrus (L) 34 322 -20,1,-13 15.98

Inferior Frontal Gyrus (L) 47 -25,29,-11 11.99

Superior Temporal Gyrus (L) 38 -56,6,-5 11.09


Parahippocampal Gyrus (R) 34 1237 21,1,-10 14.47

Caudate (R) 15,9,25 13.80

Medial Frontal Gyrus (R) 9 23,31,27 13.63

Superior Temporal Gyrus (R) 22 49,5,1 11.95

Caudate (R) 15,22,10 10.89

Middle Frontal Gyrus (R) 11 21,26,-10 10.80

Lentiform Nucleus (R) 29,-0,11 9.42

Claustrum (R) 35,-13,-3 7.38

Middle Temporal Gyrus (R) 39 167 45,-53,6 11.78

Middle Temporal Gyrus (R) 39 37,-68,15 8.20

Fusiform Gyrus (R) 37 51,-51,-15 7.40

Culmen (L) 89 -25,-33,-28 10.75

Sub-Gyral (R) 6 131 20,6,57 10.48

Precentral Gyrus (R) 6 31,-10,53 10.01

Cerebellar Tonsil (R) 41 27,-35,-32 10.33

Declive (R) 167 4,-74,-12 10.20

Uvula (L) -25,-67,-23 9.31

Culmen (L) -34,-50,-27 7.94

Inferior Parietal Lobule (L) 40 64 -54,-36,38 8.93

Fusiform Gyrus (R) 37 50 40,-54,-15 8.65


Pyramis (R) 21 26,-64,-27 8.27

Inferior Frontal Gyrus (R) 46 27 43,30,11 8.02

DFP/IC7 – negative Insula (L) 13 3498 -37,-22,7 21.57

Paracentral Lobule (L) 5 -15,-29,48 19.44

Sub-Gyral (L) -23,-41,0 18.82

Lingual Gyrus (R) 30 21,-38,-0 18.66


Cuneus (L) 17 -17,-78,2 12.85

Medial Frontal Gyrus (R) 6 12,-27,56 12.72

Cuneus (R) 17 18,-71,9 11.71

Inferior Parietal Lobule (L) 40 -40,-28,42 11.68

Culmen (R) 360 4,-49,-12 17.15

Cerebellar Tonsil (L) -6,-55,-32 8.97

Angular Gyrus (R) 39 74 37,-56,32 11.84

Inferior Temporal Gyrus (L) 20 157 -44,-4,-33 11.18

Parahippocampal Gyrus (R) 36 194 32,-19,-23 10.78

Middle Temporal Gyrus (R) 21 41,3,-31 7.86

Fusiform Gyrus (R) 20 54,-19,-28 7.61

Middle Occipital Gyrus (R) 18 47 32,-89,-0 9.98

Inferior Occipital Gyrus (L) 18 23 -28,-91,-6 8.85

TI/IC12 – positive Claustrum (L) 7980 -36,-4,-6 31.47

Claustrum (R) 37,-1,-5 31.42

Superior Temporal Gyrus (L) 22 -48,-13,5 31.31

Transverse Temporal Gyrus (R) 41 37,-25,8 27.50



Anterior Cingulate (R) 24 1,30,8 19.69





Posterior Cingulate (L) 30 324 -17,-59,4 13.63

Posterior Cingulate (R) 31 9,-63,18 12.48

Precuneus (L) 31 -9,-69,28 8.81

Fusiform Gyrus (L) 18 30 -20,-91,-11 9.08

Postcentral Gyrus (R) 7 30 9,-53,62 8.27

Declive (R) 24 23,-79,-15 7.82

TI/IC12 – negative Superior Frontal Gyrus (L) 8 4657 -20,24,44 25.08

Sub-Gyral (L) 6 -18,0,56 17.74




Caudate (R) 20,6,25 13.62


Medial Frontal Gyrus (R) 6 17,-13,52 12.25

Thalamus (L) 294 -6,-34,7 12.59

Thalamus (L) -1,-3,12 12.23

Thalamus (R) 9,-18,17 9.07

Precuneus (L) 7 51 -23,-62,39 10.15

Declive (R) 77 26,-52,-10 9.79

Medial Frontal Gyrus (L) 11 108 -3,49,-14 9.66

Superior Frontal Gyrus (R) 10 10,60,-7 9.23

Medial Frontal Gyrus (L) 11 -6,27,-11 8.46

Middle Occipital Gyrus (L) 19 55 -31,-82,10 9.57

Cuneus (L) 19 -21,-81,29 8.33

Middle Occipital Gyrus (R) 19 66 26,-80,19 9.31

Precuneus (R) 7 26 17,-57,43 8.83

CER/IC13 – positive Culmen (L) 3133 -23,-53,-21 24.27

Declive (R) 10,-59,-16 22.74


Pyramis (L) -6,-70,-23 21.22

Pyramis (R) 24,-70,-28 20.60

Tuber (L) -39,-64,-28 18.77

Culmen (R) 26,-39,-25 17.92

Culmen (L) -6,-49,-10 12.59


Lentiform Nucleus (L) 70 -12,-7,-3 10.78

Thalamus (L) -20,-20,11 7.49

Middle Frontal Gyrus (R) 8 76 37,33,38 10.23


Thalamus (R) 23,-30,2 9.22


Lentiform Nucleus (R) 24 26,8,3 7.98

CER/IC13 – negative Inferior Frontal Gyrus (L) 13 403 -34,10,-13 17.54

Inferior Temporal Gyrus (L) 20 -48,-26,-11 13.09

Middle Temporal Gyrus (L) 20 -62,-40,-10 9.82

Middle Occipital Gyrus (L) 37 -56,-63,-7 9.16


Middle Temporal Gyrus (R) 21 197 54,-27,-7 14.41

Medial Frontal Gyrus (L) 6 187 -12,4,51 13.70


Precentral Gyrus (L) 4 -12,-19,57 8.66


Precentral Gyrus (L) 6 30 -42,-1,25 9.76

Cingulate Gyrus (R) 24 24 12,-1,51 9.39


Thalamus (R) 50 4,-3,13 8.4706

RFP/IC14 – positive Medial Frontal Gyrus (R) 8 6398 4,30,37 22.60



Claustrum (R) 29,11,-1 20.67





Thalamus (R) 4,-11,12 16.25

Thalamus (R) 7,-27,-0 15.88


Pyramis (L) 482 -25,-69,-28 19.69

Declive (L) -42,-65,-15 7.64

Declive (L) -6,-76,-15 7.50


Fusiform Gyrus (R) 20 49,-31,-15 9.52



Culmen (R) 147 2,-30,-24 12.72

Culmen (R) 10,-48,-20 7.95

Cingulate Gyrus (R) 31 136 3,-42,33 12.38

Precuneus (R) 31 6,-61,29 9.09


Inferior Parietal Lobule (L) 40 -46,-62,44 10.09



RFP/IC14 – negative Middle Occipital Gyrus (R) 19 549 40,-82,8 19.59

Middle Occipital Gyrus (R) 18 23,-90,10 17.02


Lingual Gyrus (R) 18 7,-97,-6 7.62

Superior Frontal Gyrus (L) 9 445 -9,56,29 15.18




Cuneus (L) 19 325 -15,-78,29 14.28

Precuneus (L) 7 -7,-58,50 13.72

Precuneus (L) 7 -26,-52,51 8.24

Claustrum (L) 62 -31,5,10 11.24

Caudate (L) 37 -12,18,14 10.64

Cuneus (L) 17 33 -4,-98,-1 9.88


Parahippocampal Gyrus (R) 35 35,-17,-14 9.33

Cingulate Gyrus (L) 24 61 -4,-0,40 8.75

VP/IC20 – positive Anterior Cingulate (R) 24 2751 1,28,-2 41.58

Subcallosal Gyrus (R) 25 4,7,-10 28.03

Caudate (L) -14,14,0 23.92



Subcallosal Gyrus (R) 34 24,4,-12 7.32

Middle Frontal Gyrus (R) 6 34 34,5,60 10.79


Superior Frontal Gyrus (L) 6 30 -23,26,55 8.98

VP/IC20 – negative Lentiform Nucleus (L) 521 -17,-11,3 13.95

Parahippocampal Gyrus (L) -23,-9,-15 11.03

Inferior Frontal Gyrus (L) 47 -36,23,1 9.57


Superior Temporal Gyrus (L) 38 38 -39,17,-26 10.39

Thalamus (R) 100 15,-8,4 10.11

Culmen (L) 39 -6,-49,-10 9.19

Uvula (R) 21 18,-73,-25 8.26

PC/IC23 – positive Posterior Cingulate (L) 30 5726 -6,-43,22 31.11

Precuneus (R) 31 12,-63,20 29.60


Precuneus (L) 31 -7,-63,20 27.36

Precuneus (R) 7 1,-73,38 25.49

Precuneus (L) 19 -34,-70,33 20.77


Culmen (R) 7,-42,4 18.69

Thalamus (L) -6,-20,8 16.15

Thalamus (L) -26,-31,7 11.06

Precuneus (L) 7 -7,-43,49 9.91

Anterior Cingulate (L) 24 422 -0,36,8 16.15



Superior Temporal Gyrus (R) 38 154 38,14,-25 11.15


Lingual Gyrus (L) 17 23 -15,-89,1 9.96

Nodule (R) 23 7,-53,-26 9.57

PC/IC23 – negative Medial Frontal Gyrus (R) 8 653 9,38,38 13.82

Superior Frontal Gyrus (R) 6 14,-8,61 13.62




Middle Frontal Gyrus (R) 6 20,-9,42 7.55


Insula (L) 13 124 -39,-5,1 12.29


Insula (R) 13 44 34,-1,19 9.82


Cingulate Gyrus (L) 24 35 -18,-6,47 8.47

Cingulate Gyrus (R) 32 20 18,5,30 8.02

SM/IC24 – positive Precentral Gyrus (L) 6 2270 -51,-10,27 29.97


Claustrum (L) -31,-11,8 18.80


Transverse Temporal Gyrus (L) 41 -37,-34,12 13.80

Claustrum (L) -26,7,16 11.31

Cingulate Gyrus (L) 24 -9,5,37 10.12



Precentral Gyrus (R) 6 1857 48,-11,34 27.53

Superior Temporal Gyrus (R) 41 51,-25,8 16.25

Insula (R) 13 32,-9,15 13.97

Superior Temporal Gyrus (R) 22 49,-5,0 13.11

Lentiform Nucleus (R) 21,-10,-3 9.28

Declive (L) 652 -17,-59,-19 19.22

Declive (R) 7,-62,-19 18.29

Culmen (R) 26,-53,-23 12.43

Tuber (L) -36,-61,-25 10.78



Caudate (R) 18,6,22 9.63

Medial Frontal Gyrus (R) 8 9,38,38 9.39

Precuneus (L) 31 221 -1,-69,25 14.25


Cuneus (L) 19 -12,-87,34 8.71



Medial Frontal Gyrus (R) 10 30 7,46,-6 8.90

SM/IC24 – negative Claustrum (R) 133 35,14,1 17.87

Parahippocampal Gyrus (L) 36 114 -26,-40,-7 14.60

Insula (L) 13 144 -36,9,-5 13.10



Paracentral Lobule (L) 4 154 -4,-33,61 11.20

Precuneus (L) 7 -12,-57,50 7.16


Caudate (L) 66 -9,8,3 10.28

Anterior Cingulate (L) 24 100 -1,32,16 10.16

Parahippocampal Gyrus (R) 30 30 9,-48,6 8.33

Precuneus (R) 7 22 9,-47,60 8.02

MP/IC26 – positive Medial Frontal Gyrus (R) 9 4401 1,48,28 35.83








Posterior Cingulate (L) 31 1153 -4,-55,24 22.64



Thalamus (L) -9,-33,1 7.69

Thalamus (L) 103 -6,-9,12 18.46

Claustrum (L) 194 -31,6,-5 16.78



Middle Temporal Gyrus (R) 39 270 48,-61,29 14.19


Middle Occipital Gyrus (R) 19 606 29,-85,11 12.07

Inferior Occipital Gyrus (R) 19 40,-69,-6 11.24

Pyramis (R) 24,-70,-28 11.11


Declive (R) 23,-60,-10 8.03

Declive (R) 10,-80,-13 7.80

Cuneus (R) 18 12,-91,21 7.68

Tuber (L) 69 -28,-72,-26 11.77



Claustrum (L) 95 -34,-13,3 10.13

Middle Temporal Gyrus (R) 21 30 57,-27,-1 9.98


Parahippocampal Gyrus (L) 20 -25,-23,-13 9.28

Postcentral Gyrus (L) 40 83 -37,-26,45 9.27


MP/IC26 – negative Inferior Parietal Lobule (L) 1340 -29,-47,32 22.76


Precuneus (R) 7 28,-62,34 13.86

Precuneus (R) 7 3,-71,39 12.85


Claustrum (R) 72 29,13,9 12.32

Fusiform Gyrus (L) 36 175 -48,-36,-23 11.24

Caudate (L) -20,-34,15 9.65

Caudate (L) -34,-41,0 9.09

Medial Frontal Gyrus (R) 10 168 15,35,-12 11.07

Medial Frontal Gyrus (R) 25 13,16,-14 9.75



Culmen (L) 30 -3,-34,-17 10.43

Middle Frontal Gyrus (L) 11 27 -22,35,-13 9.56

Claustrum (L) 23 -25,19,3 8.72


Note: R, right; L, Left. BA = approximate Brodmann’s area. Coordinates are reported in Talairach

space.

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