functional neonatal echocardiography in haemodynamic disturbancies

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The HIP Trial is funded by the European Commission within the 7th Framework Programme Functional Neonatal Echocardiography in Haemodynamic Disturbancies Jana Semberova Institute for the Care of Mother and Child, Prague, Czech Republic

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International conference «Actual approaches to the extremely preterm babies: International experience and Ukrainian realities» (Kyiv, Ukraine, March 5-6, 2013)

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Page 1: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Functional Neonatal Echocardiography in

Haemodynamic Disturbancies

Jana Semberova

Institute for the Care of Mother and Child, Prague, Czech Republic

Page 2: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

What can we see on echo when something goes

wrong

Page 3: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Bedside neonatal echocardiography

• Targeted neonatal echocardiography

• Point of care echocardiography (POCT echo)

• Functional echocardiography

Page 4: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

WHY to perform the scan

• Circulatory failure – major cause of neonatal morbidity

and mortality

• Measures currently used to assess circulatory status

often inadequate

• Circulation management varies widely

• Lack of standardized approach

• Echo can help to assess haemodynamic status and

perhaps to guide treatment

Page 5: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

WHEN to perform the scan?

• Routine (e.g. PDA assesment)

• Clinical status

• Functional assessment – findings may change over

time, sometimes very quickly

Page 6: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

The role of functional Echo

• Structure – exclude CHD

• PDA

• PPHN

• Filling, contractility, flow

• Other: Pericardial fluid, line position etc.

Page 7: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

CHD - TOF

Page 8: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

CHD - VSD

Page 9: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

PDA – Left to Right

Page 10: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

PDA - Bidirectional

Page 11: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

PDA – flow pattern, pressure gradient

Page 12: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

PDA heart failure

Page 13: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Pulmonary Hypertension

Page 14: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

PPHN - TVI

Page 15: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Contractility assessment

Page 16: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Good Contractility

Page 17: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Poor Contractility

Page 18: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Hypertrophy

Page 19: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

LVOTO

Page 20: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Filling (preload assessment – extracardiac IVC filling)

Page 21: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Pericardial fluid

Page 22: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Line position

Page 23: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Normal Finding

Significant Left to Right Shunt - PDA

Coarctation of the Aorta

Low LV Output – Heart Failure

Abdominal Aorta Flow

Page 24: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Other findings

• Air embolia

• Tumor

• Thrombus

• Etc….

Page 25: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Functional assessment

• Quantification and normative values

• LVO, RVO – influenced by shunts

• SVC flow, SF, EF

• TDI, strain, strain rate, speckle tracking – not used

routinely in neonates, more research tools

• Visual assesment (Eyeballing)

Page 26: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Page 27: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Management

according to Echo findings ???

What to do with what we find

• Fluid administration

• Inotrope administration

• Clinical status!

• So far limited evidence of outcome improvement

Page 28: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Evolution over the time

Day 1 Day 7 Day 38

Page 29: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Evolution over the time

FS 19% FS 36%

Page 30: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

• CLOSE COOPERATION WITH PEDIATRIC

CARDIOLOGIST CRUCIAL

• Practice, recognition and availability of functional

neonatal echo varies among countries/centers

Page 31: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

TNE Guidelines

Page 32: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Practice in Czech Republic

• Tertiary units have someone who is able to perform

neonatal Echo

• Close cooperation with cardiology and cardiac surgery

(Cardiology center)

• Good prenatal diagnostics (lot of CHD recognized

prenatally-delivery in the hospital with cardiology and

cardiac surgery care)

• Self education, courses available

Page 33: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Summary

• Functional Echo – useful tool in circulatory status

assessment

• Management can’t be based on Echo findings only

• Close cooperation with cardiologist necessary

Page 34: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Special thanks to Dr. Jachym Kucera

Page 35: Functional Neonatal Echocardiography in Haemodynamic Disturbancies

The HIP Trial is funded by the European Commission within the 7th Framework Programme

Thank you for your attention