gc column selection chart
TRANSCRIPT
Zebron, Inferno, Guardian, WAXPLUS, and MultiResidue are trademarks of Phenomenex, Inc. © 2010 Phenomenex, Inc. All rights reserved.
GC Column Selection ChartThe polarity scale is based on their McReynolds value, which provides a systematic approach to ranking GC stationary phases by polarity.
2007WINNER
PO48
8111
09_L
ApplicationsColumn ProfileComposition Specifications Benefits
O O
H
H
H
H
C C
O O
H
H
H
H
C C
O O
H
H
H
H
C C
Si O
CH3
CH3
Si O
Si O
(CH2 )3
NC
Si OSi O
CH3
CH3
Si O
CH3
CH3
Si OSi O
CH3
CH3
Si O
(CH2 )3
NC
Si O
CH3
CH3
Si OSi O
CH3
CH3
Si OSi O
CH3
CH3
Si O
CH3
CH3
Si O
CH3
CH3
Si OSi O
CH3
CH3
Si O
CH3
CH3
Si O
CH3
CH3
Si O
CH3
CH3
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Scale
136 %94 %
Dimethylpolysiloxane Cyanopropylphenyl
Temperature limits -20 to 260 °C
USP phase G43Available with Guardian™ integrated guard columns
Formulated for low bleed•
Increased temperature limit speeds run times and re-equilibration•
Available in Fast GC dimensions•
Separate volatile organic flavor and fragrance additives and residual solvents •in industrial or pharmaceutical products (OVIs)
Volatile organic •compounds (VOCs)Residual solvents in •pharmaceutical products (OVIs)
US EPA Methods 501.3, •502.2, 503.1 524.2, 601, 602, 624, 8010, 8015, 8020, 8021, 8240, 8260
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Optimized for separating volatile organic compounds (VOCs)
~exclusive~
11 ProprietaryTemperature limits - 60 to 320/340 °C (isothermal/TPGC)
EPA Method 8081A, 8141, 8151 Certified
Designed for the separation of all types of pesticides, herbicides, and •insecticides
Provides baseline resolution and confirmation of all 20 chlorinated pesticides •regulated under EPA Method 8081 in ≤10 min
MS Certified phase provides low bleed performance for pesticide confirmation •by MS
Low activity, decreased breakdown of sensitive pesticides such as DDT•
Organochlorine pesticides•Organophosphorus •pesticidesNitrogen containing •pesticidesHerbicides•
Insecticides•Aroclors/PCBs•Multi-pesticide residue •methodsHaloacetic acids •
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Novel phase designed for pesticides, herbicides, and insecticides
~exclusive~
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15 Proprietary
Temperature limits - 60 to 320/340 °C (isothermal/TPGC)
EPA Method 8081A, 8141, 8151 Certified
Designed for the separation of all types of pesticides, herbicides, and •insecticides
Provides baseline resolution and confirmation of all 20 chlorinated pesticides •regulated under EPA Method 8081 in ≤10 min
MS Certified phase provides low bleed performance for pesticide confirmation •by MS
Low activity, decreased breakdown of sensitive pesticides such as DDT•
Organochlorine pesticides•Organophosphorus •pesticidesNitrogen containing •pesticidesHerbicides•
Insecticides•Aroclors/PCBs•Multi-pesticide residue •methodsHaloacetic acids•
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Novel phase designed for pesticides, herbicides, and insecticides
82007
WINNER
2009WINNER
2009WINNER
5 %95 %Dimethylpolysiloxane Phenyl
Temperature limits -60 to 400/430 °C (isothermal/TPGC)*
USP phase G27Available with Guardian™ integrated guard columns*0.53 mm ID columns are rated to 400 °C max operational temperature
Non-metal 5 % - phenyl - 95 % - dimethylpolysiloxane phase stable to •430 °C
Rugged high temperature, polyimide coated, fused silica tubing•
Provides true boiling point separation for hydrocarbon distillation methods•
Provides robust column performance for high temperature bake outs•
High boiling petroleum •productsSimulated distillation •methodsPolymers/Plastics•High molecular weight waxes•
Triglycerides•Diesel fuel•Motor oils•Surfactants•Long-chained hydrocarbons•
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staBIlItyHigh temperature stability (430 °C) for high boiling compounds
85 %95 %
Dimethylpolysiloxane Phenyl
Temperature limits -60 to 360/370 °C (isothermal/TPGC)
USP phase G27Available with Guardian™ integrated guard columns
Highly inert – improved peak shape for acidic/basic compounds•
MS certified low-bleed levels provide maximum sensitivity•
Industry leading QC specifications ensure column-to-column performance•
Traditional bonding chemistry provides the same selectivity as the ZB-5 •columns
Drugs of abuse•Nitrosamines•Phenols•
FAMEs•Pesticides•EPA Methods•
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Low-bleed column with the same selectivity as the ZB-5
9 ProprietaryTemperature limits - 60 to 340/360 °C (isothermal/TPGC)*
Available with Guardian™ integrated guard columns*Thicker films (≥1.0 µm df) are rated to 320/340 °C (isothermal/TPGC).
Temperature limits - 60 to 400 °C (isothermal/TPGC)Available with Guardian™ integrated guard columns
Unique low polarity si-arylene column for MS detectors•
Provides alternative selectivity to standard 5-type phases•
Often used for confirmation of pesticide, PCB, or other environmental samples•
Good tool for sample screening to identify unknown contaminants•
Non-metal si-arylene GC column stable to 400 ˚C•
Good tool for general screening to identify unknown samples•
Individually tested for low bleed, MS certified•
Polychlorinated Biphenyls (PCBs)•Pesticides•Herbicides•
Polychlorinated Biphenyls (PCBs)•Pesticides•Herbicides•EPA Methods•
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Low polarity si-arylene column with bleed and sensitivity levels designed for MS detectors
Enhanced durability with 400 ˚C temperature stability
85 %95 %
Dimethylpolysiloxane Phenyl-Arylene
Temperature limits -60 to 325/350 °C (isothermal/TPGC)
USP phase G27Available with Guardian™ integrated guard columns
Low bleed (MS certified) especially suited to high sensitivity work using •GC/MS
Extremely inert for active compounds such as drugs or pesticides•
Fully conditioned within 35 minutes•
Enhanced resolution of PAHs and other multi-ring aromatic compounds•
Drugs•Amines•Alkaloids•FAMEs•Halo-hydrocarbons•Dioxins•
Polyaromatic •hydrocarbons (PAHs)Polychlorinated biphenyls •(PCBs)/AroclorsAcids•Pesticides/Herbicides•
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Arylene phase for enhanced resolution of PAHs and multi-ring aromatic compounds
85 %95 %
Dimethylpolysiloxane Phenyl
Temperature limits -60 to 360/370 °C (isothermal/TPGC)*
USP phase G27Available with Guardian™ integrated guard columns*Thicker films (≥1.0 µm df) are rated to 340/360 °C (isothermal/TPGC).
Low bleed (MS certified) especially suited to high sensitivity work using •GC/MS
Extremely inert for active compounds such as drugs or pesticides•
Resilient to dirty samples – long column life•
Great column for unknown samples•
Alkaloids•Drugs•FAMEs•Halo-hydrocarbons•Phenols•Pesticides/Herbicides•
Residual solvents•PCBs/Aroclors•Essential oils/Flavors•Semi-volatiles•Dioxins•
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Versatile low polarity column for unknown samples
5100 %Dimethylpolysiloxane
Temperature limits -60 to 400/430 °C (isothermal/TPGC)*
USP phase G2Available with Guardian™ integrated guard columns*0.53 mm ID columns are rated to 400 °C max operational temperature
Non-metal 100 % dimethylpolysiloxane phase stable to 430 °C•
Rugged high temperature polyimide coated, fused silica tubing•
Provides true boiling point separation for hydrocarbon distillation methods•
Provides robust column performance for high temperature bake outs•
High boiling petroleum •productsSimulated distillation •methodsLong-chained hydrocarbons•
Polymers/Plastics•High molecular weight waxes•Diesel fuel•Motor oils•
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staBIlItyHigh temperature stability (430 °C) for non-polar compounds
5100 %Dimethylpolysiloxane
Temperature limits -60 to 360/370 °C (isothermal/TPGC)*
USP phase G2Available with Guardian™ integrated guard columns
Lowered bleed (MS certified) especially suited to high sensitivity work using •GC/MS
Extremely inert for active compounds such as drugs or pesticides•
Improved signal-to-noise ratio for better sensitivity and mass spectral •integrity
Identical selectivity to ZB-1•
Drugs of abuse•Amines•Acids•Polychlorinated biphenyls •
(EPA Method 1668)Flavors & fragrances•Diesel fuel•Pesticides•
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Extremely low bleed column for non-polar compounds
5100 %Dimethylpolysiloxane
Temperature limits -60 to 360/370 °C (isothermal/TPGC)*
USP phase G2*Thicker films (≥1.0 µm df) are rated to 340/360 °C (isothermal/TPGC).
Low activity•
High efficiency•
Excellent resolving power of critical pairs in complex petrochemical samples •
Low bleed (MS certified)•
Essential oils•Gases (refinery) •Hydrocarbons•MTBE •Natural gas odorants•
Oxygenates and GROs•Semi-volatiles•Simulated distillation•Sulfur compounds (light)•Solvent impurities•
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Non-polar phase suited for true boiling point separations
1835 %65 %
Dimethylpolysiloxane Phenyl
Temperature limits 50 to 340/360 °C (isothermal/TPGC)
USP phase G42
Temperature limits -60 to 400 °C (isothermal/TPGC)
USP phase G42
Intermediate polarity column for high molecular weight analysis•
Inert to minimize analyte adsorption, improve efficiency, and reproducibility•
More rugged (longer column life) than other polar phases•
Often resolves compounds that co-elute on ZB-1 or ZB-5 phases•
First non-metal, 35 %-Phenyl columns stable to 400 ˚C•
Great for high molecular weight compounds•
Individually tested for low bleed, MS certified•
Pesticides•Aroclors•Drugs of abuse•
Amines•Semi-volatiles•Steroids•
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Intermediate polarity column for high molecular weight
1914 %86 %
Dimethylpolysiloxane Cyanopropylphenyl
Temperature limits -20 to 280/300 °C (isothermal/TPGC)
EPA Method 8081A Certified*Thicker films (≥ 1.0 µm df) are rated to 260/280 °C (isothermal/TPGC).
Specially tested to ensure good response for DDT and endrin•
Guaranteed column for pesticide analysis•
Organochlorine pesticides•Aroclors•Organophosphorus •pesticides
Nitrogen containing •pesticidesPolaRIty
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Specially tested to ensure good response for DDT and endrin
2450 %50 %PhenylDimethylpolysiloxane
Temperature limits 40 to 320/340 °C (isothermal/TPGC)
USP phase G3
High polarity column capable of high temperature bake-out to remove •contaminants
Inert to minimize analyte adsorption, improve efficiency, and reproducibility•
More rugged (longer column life) than other polar phases•
Great for drug screening and environmental compounds•
Drugs of abuse•Pesticides/Herbicides•Aroclors•Antidepressants•
Cholesterols•Triglycerides•Steroids•Glycols•
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High polarity column capable of high temperature bake-out to remove contaminants
52100 %Polyethylene Glycol
100 % aqueous stable•
Extremely inert for acidic compounds•
Enhanced selectivity for low boiling solvents•
High retention of alcohols and chlorinated solvents•
Alcohols•Aldehydes•Aromatics•Essential oils•Flavors & fragrances•Glycols•
Pharmaceuticals•OVIs•Solvents•Styrene•Xylene isomers•Alcoholic beverages•
Temperature limits 20 to 250/260 °C (isothermal/TPGC)
USP phase G16PolaRIty
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100 % aqueous stable with high retention of alcohols and chlorinated solvents
57100 %Polyethylene Glycol
Temperature limits 40 to 250/260 °C (isothermal/TPGC)
USP phase G16
Low bleed; MS certified•
Highly stable, long lifetime•
Low activity for amines•
Excellent chromatography of polar complex mixtures•
Alcohols•Aldehydes•Aromatics•Essential oils•Flavors & fragrances•Glycols•
Pharmaceuticals •Solvents•Styrene•Xylene•Basic compounds •
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Bonded, solvent rinsable phase excellent for separating polar complex mixtures
58Nitroterephthalic Acid Modified Polyethylene Glycol
Temperature limits 40 to 250/260 °C (isothermal/TPGC)
USP phase G35
Temperature limits -20 to 260/280 °C (isothermal/TPGC)
Temperature limits -60 to 320/340 °C
Temperature limits -60 to 340/360 °C (isothermal/TPGC)
High polarity column•
Provides better peak shape for underivatized acids•
Bonded, solvent rinsable •
Replaces OV-351•
Specifically designed for blood alcohol analysis•
More accurate results for post mortem samples •
Resolves t-butanol and n-propanol, for greater selection of internal standards•
Fast run time with baseline resolution of key components in just 2 minutes•
Enhanced resolution of ethanol and acetone peaks•
Provides fast analysis with great peak shape•
Improves resolution of target analytes from matrix interferences•
Specially deactivated to improve quantitation for drug compounds•
Provides accurate and reproducible results for Certificate of Analysis (COA)•
Resolve methanol and ethanol from all other denaturant peaks•
Great resolution of fusel alcohols•
Acrylates•Alcohols•Aldehydes•Flavor mixtures•Free fatty acids•
Ketones•Organic acids•Phenols•Volatile free acids•
Blood alcohol analysis•Glycols•Abused inhalant anesthetics•Industrial solvents•
Drugs of abuse•General drug screen•Designer drugs•
Bioethanol•Alcohol•Fusel alcohols•
ASTM D 5501•ASTM D 4806•prEN 15376•
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Provides better peak shape for underivatized acids
More accurate results for blood alcohol analysis in post mortem samples
Optimized phase for the separation of drugs of abuse
Fast and accurate bioethanol analysis
Polarity Scale
Pro
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1835 %65 %
Dimethylpolysiloxane Phenyl
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9 Proprietary
loW HIgH
Enhanced durability witih 400 ˚C temperature stability
Aroclors•Semi-volatiles•Amines•EPA Methods 508, 608, •8081, 8141, 8151
Pesticides•Drugs of abuse•Pharmaceuticals•Steroids•Chemicals•
Note: Consider using ZB-MultiResidue 1 and 2 as a more rugged alternative for pesticide analysis.
Proprietary
Proprietary
Proprietary
ZB-1
ZB-1ms
ZB-1Ht INFERNo™
ZB-5
ZB-5ms
ZB-5msi
ZB-5Ht INFERNo™
ZB-XlB
ZB-XlB-Ht INFERNo™
ZB-multiResidue™-1
ZB-624
ZB-multiResidue™-2
ZB-35
ZB-35Ht INFERNo™
ZB-1701P
ZB-50
ZB-WaXPLUS™
ZB-WaX
ZB-FFaP
ZB-BaC1 & 2
ZB-dRug-1
ZB-BIoEtHaNol
www.phenomenex.com
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