generic elavil tablets for treatment of depression

Generic Elavil Tablets

Generic Elavil (Tryptomer Tablets) is used for the relief of symptoms of depression. Endogenous depression is more likely to be alleviated than are other depressive states.

Chemical Structure

The active pharmaceutical ingredient contained in Generic Elavil (Tryptomer Tablets) is Amitriptyline Hydrochloride.Each 10 mg Generic Elavil tablet for oral administration contains 10 mg of Amitriptyline Hydrochloride.

Active Ingredient

Treatment Of Depression: Generic Elavil (Tryptomer Tablets) is used for the relief of symptoms of depression. Endogenous depression is more likely to be alleviated than are other depressive states.Pain Relief: Amitriptyline Hydrochloride (Generic Elavil) is different from other pain relief drugs and is used to improve your pain control for nerve pain, for example shooting, stabbing or burning pains.

Indications

Recommended Adult Dosage

Treatment of Depression: The recommended initial dosage for adults is 75 mg of Amitriptyline HCl (Tryptomer Tablets) a day in divided doses. If necessary, this may be increased to a total of 150 mg per day. Increases are made preferably in the late afternoon and/or bedtime doses.

Recommended Adult Dosage

Pain Relief: The recommended starting dose for Amitriptyline HCl for pain is 10mg once a day. The dose is usually taken 1 or 2 hours before normal sleep time. Take the dose regularly every day. It may be 2 weeks before you start to see a real benefit. Your dose of Generic Elavil (Tryptomer Tablets) may be slowly increased to between 50mg and 75mg a day depending on how helpful it is for your pain relief.

Missed Dose

If it is almost time for your next dose, skip the dose you missed and take your next dose on schedule. Otherwise, take it as soon as you remember, and then go back to taking Generic Elavil (Tryptomer Tablets) as you would normally. Do not take a double dose to make up for the dose that you missed.

Contraindications

Generic Elavil (Tryptomer Tablets) is contraindicated in patients with the following conditions:

Hypersensitivity to Amitriptyline Hydrochloride or any inactive component of this medication.

Should not be given concomitantly with a monoamine oxidase inhibiting compound. Hyperpyretic crises, severe convulsions, and deaths have occurred in patients receiving tricyclic antidepressant and monoamine oxidase inhibiting medicines simultaneously.

Contraindications

Generic Elavil is not recommended for use during the acute recovery phase following myocardial infarction.

Amitriptyline HCl is contraindicated for the treatment of depression in patients 12 years of age and under.

Amitriptyline HCl is contraindicated for the treatment of nocturnal enuresis.

Side Effects of Generic Elavil Tablets

The following side effects have been reported with the use of Generic Elavil (Tryptomer Tablets) :Cardiovascular:Cardiovascular Hypotension, syncope, hypertension, tachycardia, palpitation, myocardial infarction, arrhythmias, heart block, stroke, non-specific ECG changes and changes in AV conduction.


CNS and Neuromuscular: Confusional states; disturbed concentration; disorientation; delusions; hallucinations; excitement; anxiety; restlessness; drowsiness; insomnia; nightmares; numbness; tingling, and paresthesias of the extremities; peripheral neuropathy; incoordination; ataxia; tremors; coma; seizures; alteration in EEG patterns; extrapyramidal symptoms, including abnormal involuntary movements and tardive dyskinesia; dysarthria; tinnitus.


Anticholinergic: Dry mouth, blurred vision, mydriasis, disturbance of accommodation, increased intraocular pressure, constipation, paralytic ileus, hyperpyrexia, urinary retention, dilatation of urinary tract.Allergic: Skin rash, urticaria, photosensitization, oedema of face and tongue.


Haematologic:Bone marrow depression including agranulocytosis, leukopenia, eosinophilia, purpura, thrombocytopenia.Gastrointestinal:Nausea, epigastric distress, vomiting, anorexia, stomatitis, peculiar taste, diarrhoea, parotid swelling, black tongue, rarely hepatitis (including altered liver function and jaundice).


Endocrine: Testicular swelling and gynecomastia in the male, breast enlargement and galactorrhea in the female, increased or decreased libido, impotence, elevation or lowering of blood sugar levels, syndrome of inappropriate ADH (antidiuretic hormone) secretion.Other:Dizziness, weakness, fatigue, headache, weight gain or loss, oedema, increased perspiration, urinary frequency, mydriasis, drowsiness, alopecia.

Warnings And Precautions

Patients of any age with Major Depressive Disorder may experience worsening of their depression and/or the emergence of suicidal ideation and behaviour (suicidality), whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs.

A major depressive episode may be the initial presentation of bipolar disorder.

Patients and their families should be alerted about the need to monitor for the emergence of anxiety, agitation, panic attacks, insomnia, irritability, hostility, impulsivity, akathisia, hypomania, mania, worsening of depression, and suicidal ideation, especially early during antidepressant treatment.


Amitriptyline HCl should be used with caution in patients with a history of seizures, in patients with impaired liver function and, because of its atropine-like action, in patients with a history of urinary retention, or with narrow angle glaucoma or increased intraocular pressure. In patients with narrow-angle glaucoma, even average doses may precipitate an attack.

Hyperpyrexia has been reported when tricyclic antidepressants are administered with anticholinergic agents or with neuroleptic medicines, particularly during hot weather.

Close supervision is required when amitriptyline is given to hyperthyroid patients or those receiving thyroid medication.


Tricyclic antidepressant medicines, including amitriptyline, particularly when given in high doses, have been reported to produce arrhythmias, sinus tachycardia, and prolongation of the conduction time. Myocardial Infarction and stroke have been reported with medicines of this class.

When Amitriptyline HCl is used to treat the depressive component of schizophrenia, psychotic symptoms may be aggravated.

Epidemioioqical studies have suggested an increased risk of congenital abnormalities associated with use of tricyclic antidepressants in pregnancy.

Storage Instructions

Keep Generic Elavil (Tryptomer Tablets) in a cool, dry place where the temperature stays below 30C. Do not store Generic Elavil, or any other medicine, in a bathroom or near a sink. Keep away from children and pets.

Overdose Symptoms

High doses of Amitriptyline Hcl (Generic Elavil Tablets) may cause temporary confusion, disturbed concentration or transient visual hallucinations. Over dosage may cause drowsiness; hypothermia; tachycardia and other arrhythmic abnormalities, such as bundle branch block; ECG evidence of impaired conduction; congestive heart failure; dilated pupils; disorders of ocular motility; convulsions; severe hypotension; stupor; coma and polyradiculoneuropathy; constipation.Other symptoms may be agitation, hyperactive reflexes, muscle rigidity, vomiting, hyperpyrexia, or any of the symptoms listed under side effects.

Overdose Treatment

All patients suspected of having taken an overdose should be admitted to a hospital as soon as possible. Treatment is symptomatic and supportive. The stomach should be emptied as quickly as possible by emesis followed by gastric lavage upon arrival at the hospital. Following gastric lavage, activated charcoal may be administered. An ECG should be taken and close monitoring of cardiac function instituted if there is any sign of abnormality.An open airway should be maintained along with an adequate fluid intake. Body temperature should be regulated.

Manufactured by Wockhardt Ltd., India.

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Tryptomer Tablets

Generic Elavil Tablets

The Swiss Pharmacy, Geneva Switzerland

generic elavil tablets for treatment of depression

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