1. Generic Tegretol TabletsGeneric Tegretol (Zeptol Tablets) is used forcontrolling Partial seizures with complexsymptomatology, Generalized tonic-clonic seizures(grand mal) and Mixed seizure patterns which includethe above, or other partial or generalized seizures(Epileptic Seizures). Generic Tegretol is also used inthe treatment of the pain associated with truetrigeminal neuralgia (facial nerve problem). The Swiss Pharmacy, Geneva Switzerland

2. Generic Tegretol TabletsChemical Structure The Swiss Pharmacy, Geneva Switzerland 3. Generic Tegretol TabletsActive IngredientThe active pharmaceutical ingredientcontained in Generic Tegretol Tabletsis Carbamazepine. Each 200 mgTegretol tablet contains 200 mg ofCarbamazepine. The Swiss Pharmacy, Geneva Switzerland 4. Generic Tegretol TabletsRecommended DosageEpilepsy:Adults and children over 12 years of age:Initial: 200 mg twice a day. Increase at weeklyintervals by adding up to 200 mg/day using a twice aday regimen until the optimal response is obtained.Dosage generally should not exceed 1000 mg dailyin children 12-15 years of age, and 1200 mg daily inpatients above 15 years of age.Maintenance: Adjust dosage to the minimumeffective level, usually 800-1200 mg daily. The Swiss Pharmacy, Geneva Switzerland 5. Generic Tegretol TabletsRecommended DosageEpilepsy Children 6-12 years of age:Initial:100 mg twice a day. Increase at weeklyintervals by adding up to 100 mg/day using a twice aday regimen until the optimal response is obtained.Dosage generally should not exceed 1000 mg dailyMaintenance: Adjust dosage to the minimumeffective level, usually 400-800 mg daily. The Swiss Pharmacy, Geneva Switzerland 6. Generic Tegretol TabletsRecommended DosageEpilepsy Children under 6 years of age:Initial: 10-20 mg/kg/day twice a day. Increase weekly toachieve optimal clinical response administered thrice aday or four times a day.Maintenance:Ordinarily, optimal clinical response isachieved at daily doses below 35 mg/kg.Combination Therapy:Tegretol may be used alone or with otheranticonvulsants. When added to existing anticonvulsanttherapy, the drug should be added gradually while theother anticonvulsants are maintained or graduallydecreased, except phenytoin, which may have to beincreased. The Swiss Pharmacy, Geneva Switzerland 7. Generic Tegretol TabletsRecommended DosageTrigeminal Neuralgia Adult Dosage:Initial: On the first day, 100 mg twice a day for atotal daily dose of 200 mg. This daily dose may beincreased by up to 200 mg/day using increments of100 mg every 12 hours, only as needed to achievefreedom from pain. Do not exceed 1200 mg daily.Maintenance: Control of pain can be maintained inmost patients with 400-800 mg daily. However,some patients may be maintained on as little as 200mg daily, while others may require as much as 1200mg daily. The Swiss Pharmacy, Geneva Switzerland 8. Generic Tegretol TabletsContraindicationsGeneric Tegretol Tablets (Zeptol Tablets) iscontraindicated in patients with the followingconditions:Hypersensitivity to Carbamazepine, or anyinactive component of this medication.In patients with a history of previous bonemarrow depression.In patients with a known sensitivity to any of thetricyclic compounds, such as amitriptyline,desipramine, imipramine, protriptyline,nortriptyline, etc The Swiss Pharmacy, Geneva Switzerland 9. Generic Tegretol TabletsContraindicationsGeneric Tegretol Tablets (ZeptolTablets) is contraindicated inpatients with the followingconditions:Its use with monoamine oxidase inhibitors is notrecommendedCoadministration of carbamazepine withnefazodone is contraindicated. The Swiss Pharmacy, Geneva Switzerland 10. Generic Tegretol TabletsSide Effects of Generic Tegretol TabletsThe most common side effects of GenericTegretol (Zeptol Tablets) are dizziness,drowsiness, unsteadiness, headache, ataxia,fatigue, diplopia, leukopenia, oedema, fluidretention, weight increase, hyponatraemia andblood osmolarity decreased, nausea, vomiting ,and allergic skin reactions (dermatitis allergic,urticaria). The Swiss Pharmacy, Geneva Switzerland 11. Generic Tegretol TabletsWarnings And PrecautionsHaematological effects: Agranulocytosis and aplasticanaemia have been associated with Tegretol; however,due to the very low incidence of these conditions,meaningful risk estimates for Tegretol are difficult toobtain. .Serious dermatologic reactions: Serious dermatologicreactions, including toxic epidermal necrolysis (TEN; alsoknown as Lyells syndrome) and Stevens-Johnsonsyndrome (SJS), have been reported very rarely withTegretol.Seizures: Tegretol should be used with caution inpatients with mixed seizures which includes absences,either typical or atypical. The Swiss Pharmacy, Geneva Switzerland 12. Generic Tegretol TabletsWarnings And PrecautionsOther dermatologic reactions: Mild skin reactions, e.g.isolated macular or maculopapular exanthema, can alsooccur and are mostly transient and not hazardous. Theyusually disappear within a few days or weeks, eitherduring the continued course of treatment or following adecrease in dosage.Renal function: Baseline and periodic completeurinalysis and BUN determinations are recommended.Anticholinergic effects: Tegretol has shown mildanticholinergic activity. Patients with increased intraocularpressure should therefore be closely observed duringtherapy. The Swiss Pharmacy, Geneva Switzerland 13. Generic Tegretol TabletsWarnings And PrecautionsPsychiatric effects: The possibility of activation of alatent psychosis and, in elderly patients, of confusion oragitation should be borne in mind. An analysis of reports ofsuicidality from placebo-controlled clinical studies ofeleven medicines used to treat epilepsy as well aspsychiatric disorders, and other conditions revealed thatpatients receiving an ti-epileptic drugs had approximatelytwice the risk of suicidal behaviour or ideation (0.43%)compared to patients receiving placebo (0.22%).Endocrinological effects: The reliability of hormonalcontraceptives may be adversely affected by Tegretol andwomen of childbearing age should be advised to considerusing alternative forms of birth control while takingTegretol. The Swiss Pharmacy, Geneva Switzerland 14. Generic Tegretol TabletsOverdose SymptomsThe first signs and symptoms of overdoseappear after 1 to 3 hours. Neuromusculardisturbances are the most prominent.Cardiovascular disorders are generally milder,and severe cardiac complications occur onlywhen very high doses (>60 g) have beeningested. The Swiss Pharmacy, Geneva Switzerland 15. Generic Tegretol TabletsOverdose SymptomsRespiration: Irregular breathing, respiratorydepression.Cardiovascular System: Tachycardia, hypotension orhypertension, shock, conduction disorders.Nervous System and Muscles: Impairment ofconsciousness ranging in severity to deep coma.Convulsions, especially in small children. Motorrestlessness, muscular twitching, tremor, athetoidmovements, opisthotonos, ataxia, drowsiness,dizziness, mydriasis, nystagmus, adiadochokinesia,ballism, psychomotor disturbances, dysmetria. Initialhyperreflexia, followed by hyporeflexia.Gastrointestinal Tract: Nausea, vomiting. The Swiss Pharmacy, Geneva Switzerland 16. Generic Tegretol TabletsOverdose SymptomsKidneys and Bladder: Anuria or oliguria, urinaryretention.Laboratory Findings: Isolated instances ofoverdosage have included leukocytosis,reduced leukocyte count, glycosuria, andacetonuria. EEG may show dysrhythmias.Combined Poisoning: When alcohol, tricyclicantidepressants, barbiturates, or hydantoins aretaken at the same time, the signs andsymptoms of acute poisoning with Tegretol maybe aggravated or modified. The Swiss Pharmacy, Geneva Switzerland 17. Generic Tegretol TabletsOverdose TreatmentIn cases of severe poisoning is criticallydependent upon prompt elimination ofGeneric Tegretol which may be achievedby inducing vomiting, irrigating thestomach, and by taking appropriate stepsto diminish absorption. If these measurescannot be implemented without risk onthe spot, the patient should be transferredat once to a hospital, while ensuring thatvital functions are safeguarded. There isno specific antidote. The Swiss Pharmacy, Geneva Switzerland 18. Generic Tegretol TabletsZeptol Tablets manufactured bySun PharmaceuticalsFor more information click here The Swiss Pharmacy, Geneva Switzerland