genetic disorders bedlington terrier

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Genetic Disorders Genetic Disorders Bedlington Terrier Bedlington Terrier

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Page 1: Genetic Disorders Bedlington Terrier

Genetic DisordersGenetic Disorders

Bedlington TerrierBedlington Terrier

Page 2: Genetic Disorders Bedlington Terrier

Introduction Introduction

When choosing any breed of dog you must be When choosing any breed of dog you must be aware of potential health concerns aware of potential health concerns All dogs mixes and pure bred can have health All dogs mixes and pure bred can have health concerns concerns The more popular breeds and their mixes will The more popular breeds and their mixes will have more genetic problems listed and more have more genetic problems listed and more likely to have puppies with problems . likely to have puppies with problems . Make sure your breeder offers a written health Make sure your breeder offers a written health guarantee good for one year.guarantee good for one year.Have the puppy heath checked at your Have the puppy heath checked at your VeterinarianVeterinarian

Page 3: Genetic Disorders Bedlington Terrier

Gastrointestinal DisordersGastrointestinal Disorders

Chronic hepatitisChronic hepatitis is a catch-all diagnosis for a number of is a catch-all diagnosis for a number of diseases where there is inflammation and death of liver diseases where there is inflammation and death of liver tissue. Affected dogs develop a slowly progressive liver tissue. Affected dogs develop a slowly progressive liver disease. There are many possible causes including disease. There are many possible causes including viruses, bacterial infection, and some drugs. A familial viruses, bacterial infection, and some drugs. A familial predisposition to the development of chronic hepatitis predisposition to the development of chronic hepatitis exists in some breeds, although the cause is unclear. exists in some breeds, although the cause is unclear. These breeds are listed below.These breeds are listed below.In Bedlington terriers an inherited defect in the In Bedlington terriers an inherited defect in the metabolism of copper is known to cause chronic metabolism of copper is known to cause chronic hepatitis (copper-associated hepatitis/copper toxicosis in hepatitis (copper-associated hepatitis/copper toxicosis in Bedlington terriers). It is estimated that 25% of Bedlington terriers). It is estimated that 25% of Bedlington terriers have the disorder, and 50% are Bedlington terriers have the disorder, and 50% are carriers (ie. they will not become ill, but can transmit the carriers (ie. they will not become ill, but can transmit the disorder to their offspring). disorder to their offspring).

Page 4: Genetic Disorders Bedlington Terrier

Eye DisordersEye Disorders

GlaucomaGlaucoma is a leading cause of blindness in dogs. It is the result of is a leading cause of blindness in dogs. It is the result of increased fluid pressure within the eye (elevated intraocular increased fluid pressure within the eye (elevated intraocular pressure or IOP). If the pressure can not be reduced, there will be pressure or IOP). If the pressure can not be reduced, there will be permanent damage to the retina and optic nerve resulting in visual permanent damage to the retina and optic nerve resulting in visual impairment. Complete blindness can occur within 24 hours if the impairment. Complete blindness can occur within 24 hours if the IOP is extremely elevated or can occur slowly over weeks or months IOP is extremely elevated or can occur slowly over weeks or months if the elevation is mild. Glaucoma is usually very painful. It is if the elevation is mild. Glaucoma is usually very painful. It is considered a medical emergency Unfortunately it is not usually considered a medical emergency Unfortunately it is not usually apparent until dogs reach 3 year of ageapparent until dogs reach 3 year of age . .CataractsCataracts:: Can be congenital, juvenile or as a result of old age Can be congenital, juvenile or as a result of old age Retinal dysplasiaRetinal dysplasia:: The condition is present from birth. At 3 to 4 weeks The condition is present from birth. At 3 to 4 weeks of age, the breeder may notice that severely affected pups are less of age, the breeder may notice that severely affected pups are less active and frequently bump into objects. A veterinarian will be best active and frequently bump into objects. A veterinarian will be best able to examine the pup's eyes for this condition with an able to examine the pup's eyes for this condition with an ophthalmoscope at 12 to 16 weeks of age, when the retina is ophthalmoscope at 12 to 16 weeks of age, when the retina is maturemature

Page 5: Genetic Disorders Bedlington Terrier

Eye DisordersEye DisordersProgressive retinal atrophyProgressive retinal atrophy: : deterioration of the retinal cells causes blindness. deterioration of the retinal cells causes blindness. Generalized PRA - early onset:Generalized PRA - early onset: The first sign is generally failing night vision, as The first sign is generally failing night vision, as early as 6 weeks of age, and this progresses to complete loss of vision by about 1 - 2 early as 6 weeks of age, and this progresses to complete loss of vision by about 1 - 2 years of age. Collies may retain some vision until the age of 2 - 3 years. In miniature years of age. Collies may retain some vision until the age of 2 - 3 years. In miniature schnauzers, poor night vision usually develops later (6 months to a year) and there is schnauzers, poor night vision usually develops later (6 months to a year) and there is advanced loss of vision by 3 to 4 years. Affected Alaskan malamutes are day-blind advanced loss of vision by 3 to 4 years. Affected Alaskan malamutes are day-blind (hemeralopia) at 8 to 10 weeks of age; night vision is never affected.(hemeralopia) at 8 to 10 weeks of age; night vision is never affected.

Generalized PRA (progressive rod-cone degeneration) - late onset:Generalized PRA (progressive rod-cone degeneration) - late onset: Generally Generally night blindness is noticed between 2 and 5 years of age (depending on the breed) night blindness is noticed between 2 and 5 years of age (depending on the breed) progressing to total blindness within a year or so. Peripheral vision is lost first.progressing to total blindness within a year or so. Peripheral vision is lost first.

Central PRA (CPRA) - retinal pigment epithelial dystrophy (RPED): Central PRA (CPRA) - retinal pigment epithelial dystrophy (RPED): Loss of vision Loss of vision occurs much more slowly than in generalized PRA, without initial night blindness. occurs much more slowly than in generalized PRA, without initial night blindness. Affected dogs may not lose vision completely. Because the changes are in the centre Affected dogs may not lose vision completely. Because the changes are in the centre of the retina, affected dogs initially have trouble locating still objects in bright light. of the retina, affected dogs initially have trouble locating still objects in bright light.

Page 6: Genetic Disorders Bedlington Terrier

In ConclusionIn ConclusionBedlington Terriers have 5 health concerns Disorders relatively common in this breed are : Chronic Hepatitis , Retinal Dysplasia

Note above disorder(s) is very common in this breed. Do not take lightly the other disorders. Some are very serious .

Information for this presentation as a public service provided by: www.delayrekennel.com with information provided by :

A joint initiative of the Sir James Dunn Animal Welfare Centre at the Atlantic Veterinary College, University of Prince Edward Island, and the Canadian Veterinary Medical Association..

Permission is granted to reprint pages from the database, provided that credit is given as follows: Crook A et al. 2011. Canine Inherited Disorders Database

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Page 7: Genetic Disorders Bedlington Terrier

About the PresenterAbout the Presenter

Member of the Canine Ambassador Program with Orange Empire Member of the Canine Ambassador Program with Orange Empire Dog Club. Educating people in the joy canines bring into our lives Dog Club. Educating people in the joy canines bring into our lives through their relationship, interaction, and unconditional love. through their relationship, interaction, and unconditional love. Pet Professional specializing in the training of puppies in Sun Valley Pet Professional specializing in the training of puppies in Sun Valley since 1974 . since 1974 . Breeder of Silky Terriers and Wire Fox TerriersBreeder of Silky Terriers and Wire Fox TerriersMy boarding, training and breeding kennel was awarded Small My boarding, training and breeding kennel was awarded Small Business of the Year 2000 Business of the Year 2000 Better Business Bureau A+ rating Better Business Bureau A+ rating I have owned and/or bred 21 Conformation Champions including 6 I have owned and/or bred 21 Conformation Champions including 6 International Champions International Champions Member and former Vice President of the City of Angels Silky Member and former Vice President of the City of Angels Silky Terrier ClubTerrier ClubPast President of Sun Valley Chamber of CommercePast President of Sun Valley Chamber of CommerceHave also served on the boards of Associated Terrier Breeders, Have also served on the boards of Associated Terrier Breeders, Animal Safe Haven Foundation, United Chambers of CommerceAnimal Safe Haven Foundation, United Chambers of Commerce