Genotyping Results

Each person was typed for 3 unlinked Short Tandem Repeat loci (STR)

vWFII – chromosome 12, intron 40 of the vWF geneUT 2203 – chromosome 4, 60.16 cMUT 1376 – chromosome 4, 132.05 cM

Individual genotyping results are in the MED2011_FALL_Genotypes.pdf file

Allele frequencies for this class are compared to previous medical school classes and to other world populations using a neighbor-joining tree based on genetic distance estimates

Example – 3 STR markers

UT1376 288, 288

UT2203 199, 202

vWFII 154, 162

A size marker (orange)is used to establish allele sizes

STR Genotype

150-180 bp

Size ranges for all alleles 185-205 bp 277-305 bp

vWFII UT2203 UT1376

Allele frequencies

vWFII UT2203 UT1376

allele (bp) allele (bp) allele (bp)

freq

uen

cy

freq

uen

cy

freq

uen

cy

Genotype Summary and Sharing83 Participants, 3 STRs

vWFII Counts154, 162 7154, 166 4154, 174 2158, 162 5158, 166 4158, 170 1162, 162 9162, 166 19162, 170 1162, 174 2162, 178 2164, 168 1166, 166 8166, 170 2166, 174 3170, 174 1174, 174 3

No call 9

UT2203Count

s199, 199 24199, 202 39202, 202 9

No call 11

UT1376 Counts281, 289 2285, 285 1285, 289 10285, 293 2285, 297 1289, 289 25289, 293 16289, 297 1291, 291 1293, 293 2293, 297 1

No call 21

3 Loci Combined Counts162, 166 199, 199 289, 289 4158, 162 199, 202 289, 289 3162, 166 199, 202 281, 289 2162, 162 199, 202 289, 289 2162, 162 199, 199 289, 289 2

No Call 25Unique 45

Population Tree