Geographical Management of Cancer Health Disparities Program

(GMaP)&

Biospecimen Science Management of Cancer Health

Disparities Program (BMaP)

Program Meeting

July 14, 2011

1

Welcome and Opening Remarks

2

Session I – G/BMaP Overview & Update

Session II – Panel Discussion Identifying Funding, Training, and Collaboration Opportunities

Session III – Envisioning the G/BMaP Initiative: Short Term• New collaborations and projects

• New supplement guidelines

Session IV – Envisioning the G/BMaP Initiative: Long Term• Partnership/Organizational Structure

• Nature of Research Question

• Scope/Structure: Training, Biospecimens

3

Session IG/BMaP Overview & Update

4

5

200920082006 2010 2011

Summit 2006

2 Original Pilots 12 ARRA Supplements

Region 6University of

California Davis

Region 1Georgetown

University

• GMaP Summit

• Regional Needs Assessments

• Evaluation• Program

Meeting• Implementation

Plan

6

Region 1

Region 2

Region 3

7

Ming Zhao NCI-CRCHD G/BMaP Program DirectorLucile Adams-Campbell Georgetown Lombardi Comprehensive Cancer Center BMaP PISarah Reisinger Georgetown Lombardi Comprehensive Cancer Center BMaP RCSteve Patierno George Washington Cancer Institute GMaP PISarah Hijaz George Washington Cancer Institute GMaP RC

Liz Perruccio NCI-CRCHD G/BMaP Program DirectorSamuel Adunyah Meharry Medical College BMaP PIRoland Cooper Meharry Medical College BMaP RCSteven Akman Wake Forest University Health Sciences GMaP PITasha Smith Wake Forest University Health Sciences GMaP RC

Mary Ann Van Duyn NCI-CRCHD G/BMaP Program DirectorJack Pledger H. Lee Moffitt Cancer Center & Research Institute BMaP PIDiana Lima H. Lee Moffitt Cancer Center & Research Institute BMaP RCEdward Partridge University of Alabama at Birmingham GMaP PICathy Meade H. Lee Moffitt Cancer Center & Research Institute GMaP PIIsabel Scarinci University of Alabama at Birmingham GMaP PITeresita Antonia H. Lee Moffitt Cancer Center & Research Institute GMaP PIAllison McGuire University of Alabama at Birmingham GMaP RC

Region 4

Region 5

Region 6

8

Anil Wali NCI-CRCHD G/BMaP Program DirectorMary O'Connell New Mexico State University BMaP PILeticia Vilchis New Mexico State University BMaP RCAmelie Ramirez University of Texas Health Science Center at San Antonio GMaP PIKipling Gallion University of Texas Health Science Center at San Antonio GMaP PIAlan E. C. Holden University of Texas Health Science Center at San Antonio GMaP RC

Rina Das NCI-CRCHD G/BMaP Program DirectorJulian Schink Northwestern University BMaP PISteve Rosen* Northwestern University BMaP PIErika de la Riva Northwestern University BMaP RCRobert Beck Fox Chase Cancer Center GMaP PILinda Fleisher Fox Chase Cancer Center GMaP PIMelissa Simon Northwestern University GMaP PIDelroy Louden Lincoln University GMaP PICarrie Norbeck Fox Chase Cancer Center GMaP RC

Carmen Moten NCI-CRCHD G/BMaP Program DirectorElizabeth Klonoff Comprehensive SDSU/UCSD Cancer Center Partnership BMaP PIEbere Iweriebor Comprehensive SDSU/UCSD Cancer Center Partnership BMaP RCBeti Thompson Fred Hutchinson Cancer Research Center GMaP PIHeidi Harbach Fred Hutchinson Cancer Research Center GMaP RC

Program Goals GMaP BMaP

Advance the science of cancer health

disparities in these regions

Contribute to the next generation of cancer health

disparities researchers

Achieve measurable

reductions in cancer health disparities in these regions

Create unique, centralized, public resources for multiethnic

biospecimen collection/banking, which ensure that samples are:

From diverse cultural backgrounds

Of high quality

Broadly available to researchers

Guiding Principles

Building G/BMaP Connectivity Bridging between existing NCI/NIH supported Research and Training Programs and G/BMaP Networks

E.g. CNP, PNRP, PRCHD, CURE Trainees; NON, NCCCP, SPORES, MB-CCOPS/CCOPS, GWAS, TCGA, EDRN; NCCR, ACS

Building Collaborative Research Capacity: Growing a Team Science and Collaborative Research Base within our Regions

E.g. RO1s,PO1s, SPORE-like Grants, Cooperative Agreements, Contracts

Infrastructure• 12 G/BMaP RC (and National

Coordinator)• Elective and Core Leads in place• Regional communication in

place

Partnership• 17 Regional Planning Meetings • 72 Institutions participated in

the RAT• Regional expansion

• Output• Several publications• 16 Abstracts/posters• Website

development • BMaP Database Pilot

Proposal

Accomplishments to Date

NCI Investment to date: $2.9M + 12 ARRA supplements in FY09 These funds have supported enhanced:

Value of Collaborating Regionally to Address Disparities

Improves the state of disparities science• Highlights importance of reaching across programs and

institutions• Leveraging institutional resources and breaks down

research silos• Enhances research and training capabilities regionally

and for community benefit

Value of Collaborating Regionally to Address Disparities

Benefits the researcher, as well• Improves

• programmatic activities• tracking and support of patients between jurisdictions• faculty/trainee/student participation in CHD research

• Expands• capacity for unaddressed issues within a region

• Enhances• design of collaborative regional studies• access to shared resources 13

Looking Ahead

Changing Healthcare Environment: Health Reform• Government role will increase

• Access and coverage will expand at payment rates lower than current levels

• Changes to the structure and methods of payment for providers

• Management role in healthcare delivery decisions will increase

15

NCI Research Funding

• NCI funding will remain flat for the foreseeable future

• Comparative effectiveness research will be funded

• Leveraging resources to support NCI goals will be important

16

Collaborations Will Be Key

17

Collaborations Will Be Key

Short Term

• New collaboration• New supplement opportunities

New Collaboration: BMaP Pilot

• Test the feasibility of developing a central, searchable, web-based database of de-identified biospecimen data for collaborative research in cancer health disparities

Facilitate joint, hypothesis –driven research collaborations across sties

Enable data sharing Provide access to research/tools Establish proof-of-principle for team science

New Supplement Opportunities

BMaP170K TC/Region/one yr.5 FTE BMaP Coordinator + .5

FTE BMaP Database Entry

GMaP170K TC/Region/one yr1 FTE GMaP Coordinator

Key Activities• Sustain infrastructure• Strengthen partnership

base (NON, CURE, NCCCP)

• Conduct Year 1 of two year pilot

Key Activities• Sustain infrastructure• Strengthen partnership base

(Community)• Participate in cross-regional

BMaP biospecimen database pilot

Supplement TimelineKey Dates

Release date July 11, 2011

Submission deadline July 27, 2011

Anticipated start date September 1, 2011

Long Term

• Questions for discussion

Questions for DiscussionHow should G/BMaP be structured in the future?

•Should institutions join individually or in pairs?

•Should equal numbers of majority/minority institutions be mandated?

•How do we ensure community engagement?

How should G/BMaP conduct research in the future?

•Should each region focus on one disparities research problem or pursue multiple topic areas?

How should G/BMaP be organized in the future?

•Can we improve G/BMaP’s current mix of cores/electives?

•How can we include the training of diverse investigators into G/BMaP?

Thank you!