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Glaucoma Tasneem Al-Abbadi

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Page 1: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Glaucoma

Tasneem Al-Abbadi

Page 2: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Definition

Pathophysiology

Classification and symptom

Diagnosis

treatment

Page 3: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

It is a group of eye diseases in which damage to the optic nerve (optic neuropathy) is usually “ not always” caused by raised ocular pressure (normal IOP is 15.5 mmHg) acting

on the nerve head

Its optic neuropathy and visual field defect

with or without increase intraocular pressure

Definition

Page 4: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Definition

Pathophysiology

Classification and symptom

Diagnosis

Treatment

Page 5: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Anatomy physiology pathology

Pathophysiology

Page 6: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Pathway of aqueous humor flow:

Anatomy physiology pathology

Conventional pathway

Uveo-scleal Pathway

Page 7: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Anatomy physiology pathology

Mechanical damage To optic nerve axons by the raised IOP Ischemia of nerve fibers caused by impaired perfusion pressure (reducing blood flow at optic nerve head)

Page 8: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

-Family history of glaucoma

-Age 60 and older.

-Eye injury , certain eye surgeries or chronic eye inflammation.

-Diabetes, high blood pressure, heart disease or hypothyroidism .

-steroids for long periods of time

Risk factors of glaucoma:

Page 9: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Definition

Pathophysiology

Classification and symptom

Diagnosis

treatment

Page 10: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Classification

Primary glaucoma Congenital glaucoma Secondary glaucoma

Chronic open angle glaucoma Acute and chronic closed angle glaucoma

Primary Rubella Secondary to other inherited ocular disorders (e.g. aniridia; absence of iris)

**Corneal diameter will be increased. **white eye NOT red

Trauma Ocular surgery Associated with other ocular diseases (uveitis) by { hypopyon , posterior synechea , steriod tt } Raised episcleral venous pressure Steroid induced

Page 11: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Open angle glaucoma

The angle between cornea and iris

The drainge system slowly gets clogged over time ,so gradual increase in pressure in optic nerve

This increase result in atrophy of outer rim of nerve that result in decrease peripheral vision

Over time loss in central vision

Page 12: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea
Page 13: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Mening the passage for aqueous humor outflow is too narrow that push lens against iris

Rapid incrase in pressure

Severe eye pain redness blurred vision headache nausea visual haloes

Closed angle glaucoma narrow

Open angle glaucoma~most

common

Page 14: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Because the vision loss is gradual, usu. Bilateral and asymmetrical the patient usually present when severe damage has occurred & Its painless .

Most patients are detected by optometrist routine examination. Other sign is disck cupping .

Visual field defect : Gradual loss of peripheral vision, usually in both eyes, Tunnel vision in the advanced stages

Symptoms

Page 15: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Definition

Pathophysiology

Classification and symptom

Diagnosis

treatment

Page 16: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

IOP

Viual field

Look for optic nerve :direct observation

imaging{cupping}

Diagnosis

Thining the outer rim of

nerve

POAG criteria: (you need 2 out

of 3)

Page 17: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

POAG criteria: (you need 2 out of 3) 1. IOP 2. Visual field changes 3. Optic nerve damage (cupping) Cupping takes place first then the visual field changes.

Visual field changes: 1) nasal step 2) arcuate scotoma 3) tunnel vision 4) blurring in central vision

POAG: Primary open angle glaucoma

Page 18: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

The optic disc marks the exit point of the retinal nerve fibers from the eye. With a sustained rise in IOP the nerve fibers atrophy, leaving the characteristic sign of chronic

glaucoma—the cupped, pale optic disc.

Optic disc cupping

Page 19: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Definition

Pathophysiology

Classification and symptom

Diagnosis

Treatment

Page 20: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Aim of treatment is to decrease the IOP Amount of decrease depends on the level at which no more damage to the optic nerve happens .

This level differs from patient to other

Modalities :

1- Medical Treatment

2- Laser Treatment

3- Surgical Treatment

Management:

Page 21: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Decrease production of aqueous humor

Increase outflow of aqueous humor

Increase outflow and Decrase production

Medical Treatment

Beta adrenergic receptor antagonist

Prostaglandin analogis

Alpha adrenergic

agonist

Page 22: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Trabeculoplasty Open trabecular meshwork for open angle glaucoma

Iridotomy Use laser to puch a tiny hole in iris to treat close angle glaucoma

Surgical Treatment

Page 23: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea

Definition

Pathophysiology

Classification and symptom

Diagnosis

treatment

Page 24: Glaucoma · Mening the passage for aqueous humor outflow is too narrow that push lens against iris Rapid incrase in pressure Severe eye pain redness blurred vision headache nausea