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    The Facts of Life for

    Researchers

    There are more applications for grant support thanever before.

    Resources are either constant or diminishing.

    Approximately one application in seven is funded;approximatelysix-of seven applications fail.

    It is, therefore, essential that individuals planning inthis careers understand the grant writingprocess.

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    Any Well-trained Person Can

    Become Funded

    YOUR KEYS TO SUCCESS

    Your Idea!

    Your Commitment!

    Your Grant-Writing Skills!

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    YOUR IDEA IS KEY!

    HOW TO DEVELOP

    AN IRRESISTIBLE,

    FUNDABLE IDEA?

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    What Makes an Idea Irresitible?

    Paradigm Shifters

    Paradigm Pioneers

    Settlers

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    The Important of Being First!

    You Need to MakeYourselfFirst in

    Whatever Category

    You Choose!

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    KEY Elements in

    Developing a Good Idea

    Be KnowledgeableExtensively read existing literature.

    Be ThoughtfulDevote time to just thinking.

    Be OpenShare ideas with your colleagues.

    Be Creative

    Look for parallels with other fields.

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    Critical Assessment

    of Your Ideas

    Assess Yourself

    Assess the Competition

    Assess Funding Potential

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    Assess Yourself

    Critically assess whether you have thenecessary expertise, resources, personnel,time, preliminary studies, data, or otherevidence of productivity in order to betruly competitive.

    It could be that the worst thing that couldhappen to you is that you would receivea grant award before you are truly ready.

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    Assess the Competition

    Thoroughly search the literature

    Use reference databases extensively

    (e.g.,Pubmed, Science Citation Index, Medline,

    Highwire, etc.)

    Search databases of funded grants

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    Search the Biomedical Literature

    http://highwire.stanford.edu

    A free Highwire Email-alerting Service

    Frequent notification of published articles that

    match your interest

    No limit to number of alerts you can register

    Match interests by either author or subject

    Provides hyperlink to the article/abstract

    Access to the article is often free

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    Search the Biomedical Literature

    PubCrawler

    http://www.pubcrawler.ie

    Medline and Genbank searches

    Provides informationdaily

    Either email or web-based format

    It goes to the library. You go to the pub!

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    Assess the CompetitionSearch databases of existing grants:

    CRISP(Computer Retrieval of Information on Scientific Projects)http://crisp.cit.nih.gov/

    CRIS(Current Research Information System)http://cristel.nal.usda.gov:8080

    NSF Awards

    http:www.nsf.gov/verit/srchawad.htm

    Community of Sciencehttp://fundedresearch.cos.com

    NASA Task Bookhttp://peer1.nasaprs.com/peer review/taskbook/

    http://fundedresearch.cos.com/http://peer1.nasaprs.com/peer%20review/taskbook/http://peer1.nasaprs.com/peer%20review/taskbook/http://fundedresearch.cos.com/
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    Assess Potential for Funding

    Find theAgency andFunding MechanismThat Fits Your Idea

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    Assess Potential for Funding

    Since all funding agencies have amission, it is

    important to:

    Understand that funding your proposal must help

    the funding agency achieve its goals.

    Know what an agency can/will fund.

    Become aware of all agency programannouncements regarding research

    opportunities.

    Contact theprogram officer first and listen carefully

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    Know How Applications

    Are Made to NIH

    Investigator-initiated application Most common kind

    Response to Program Announcement (PA) No fund set aside

    Regular receipt dates; regular study section

    Program can fund out of priority order

    Response to Request for Applications (RFA) Funds are set aside

    One date for receipt; special study section

    Your project must fit the need closely to be competitive

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    NIH

    Small Research Grants (R03)

    Does not disqualify applicant as a new investigator

    Not all NIH Institutes support R03

    Check with institute program officers

    Less emphasis is placed upon preliminary data

    Therefore, a useful mechanism of developing

    preliminary data for later R01 application

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    Exploratory/Developmental

    Grants (R21)

    Encourage development of new research activities in categoricalprogram areas.

    Used by Institutes to innovate in specificprogrammatic areas (PA/RFA)

    Oftenhigh risk/high return research

    Often limited/no need for preliminary data

    Limited time and budget

    Encourage subsequent R01 support

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    NIH Program Officers

    Are of Great Value to You

    Planning Phase: Help you to choose funding vehicle and to understand priorities

    Writing Phase: Can help establish appropriate scope

    Sometimes will provide feedback on aims

    Submission: Assistance with the cover letter

    Review Phase: Important feedback on proposals review and on future submission

    Funding Phase:

    Advocate within the program

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    NIH Process

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    Identifying Potential

    Funding Opportunities

    Proactively Search for Funding Opportunities

    It is critical to identify funding opportunities at the

    earliest possible time

    Periodically contact Program Officer

    Take full advantage of your Institutional resources

    Also plan to personally invest search time weekly

    Use a planned search strategy

    Take full advantage of the internet

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    Use Email Alert Services

    Community of Science

    http://www.cos.com/services/fundings.html

    NSFs Custom News Service

    http://www.nsf.gov/home/cns/index.cfm

    Grantsnet

    http://www.grantsnet.com

    Grants.gov

    http://www.grants.gov/ReceiveGrantOppotunitieyNotification

    http://www.nsf.gov/home/cns/index.cfmhttp://www.grantsnet.com/http://www.grants.gov/ReceiveGrantOppotunitieyNotificationhttp://www.grants.gov/ReceiveGrantOppotunitieyNotificationhttp://www.grantsnet.com/http://www.nsf.gov/home/cns/index.cfm
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    Federal Research Budgets

    for the BIG SIX for 2005

    Funding Agency 2005 Budget % Change 2004

    NIH ~$28.6 billion + 2.0%NASA ~$16.1 billion + 4.5%

    DOD ~$70.3 billion + 7.1%

    DOE ~$3.3 billion + 4.3%

    NSF ~$5.5 billion - 1.9%

    USDA ~$2.4 billion + 7.8%

    NEH ~$0.1 billion 0%

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    YOUR SECOND KEY IS

    COMMITMENT!

    To Research

    To the Grant-Writing Process

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    Do You Really Want to Compete?

    Identify and stay focused on your longterm goal; avoid diversification

    Conscientiously get to know your field; theliterature, the leaders, the funding sources

    Network: success rarely develop out of shyness

    Always be mentally prepared for rejection

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    An Essential Need of a

    Committed Grant Writer

    CREATE TIME

    Time to look for funding opportunities

    Time to understand what is required to becompetitive

    Time to write a competitive proposal

    Time to get critical review from your colleagues

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    Maximize Lead Time

    Takes Commitment

    Proactively Search for

    Funding OpportunitiesThe window of opportunity for many grant

    applications is often open for only a limited

    time.It is, therefore,criticalto identify funding

    opportunities at the earliest possible time.

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    Maximize Lead Time

    Takes Commitment

    Lead Time is Important!

    NIH Request for Application (RFA)

    OVERWEIGHT AND OBESITY IN THE WORKPLACE

    Release date: October 7, 2003

    RFA: HL-04-006Letter of Intent Deadline: February 15, 2004*

    Application Receipt Deadline: March 12, 2004**

    * Average is 3-4 months ** Average is 4-8 months

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    Maximize Lead Time

    Takes Commitment

    Finding NIH RFAs

    http://grants1.nih.gov/grants/guide/rfa-files/index.html

    This index is updated every Friday afternoon.

    http://grants1.nih.gov/grants/guide/rfa-files/index.htmlhttp://grants1.nih.gov/grants/guide/rfa-files/index.htmlhttp://grants1.nih.gov/grants/guide/rfa-files/index.htmlhttp://grants1.nih.gov/grants/guide/rfa-files/index.html
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    Create Quality Time

    Takes Commitment

    Clear your schedule to the greatest extentpossible

    Eliminate non-essential activities

    Minimize disruptive influences, e.g.,schedule phone, email, and office hours

    Write time on your dayplanner to work onfunding opportunities

    Learn to say NO!

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    Create Quality Time

    Takes Commitment

    Time to get in-house review of your proposal:

    It is essentialthat you getcriticalreview from yourknowledgeable colleagues.

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    YOUR THIRD KEY IS

    GRANTSMANSHIP SKILLS!

    Successful Grantsmanship requires that you pay attention to:

    Mechanics - knowing how to fill out the form correctly

    Conceptunderstanding the purpose of grantapplications

    Psychologyappreciating that grant applications areread by people

    Writingadopting the tricks of the trade used by

    professional grant writers Logicpresenting your ideas in a clear and maximally

    understandable way

    Timeunderstanding that writing a quality applicationalways takes time

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    YOUR THIRD KEY IS

    GRANTSMANSHIP SKILLS!

    Know where/how to for funding opportunities

    Maximally convey enthusiasm for your novel idea

    Write with maximal clarity & compelling logic

    Ensure compatibility with mission of funding agency

    Inform the funding agency what to expect for their

    investment in you. Make your application reviewer friendly

    Avoid avoidable mistakes

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    Elements of Grant Success

    Good Good

    Ideas Reviewers

    Good Good

    Timing Luck

    Good GoodPresentations Grantsmanship

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    Good Grantsmanship

    Knowing & understanding What to do

    How to do it When to do it

    What to dowhen things dont go as planned

    Being willing to do what is needed Passion & Commitment

    Doing itdoing what is needed Commitment

    Understanding Peer Review Process

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    Most Common Reasons

    for Application Failure

    Lack of a good, original idea

    Lack of sufficient commitment

    1. Problem to be studied lacks significances

    2. Lack of an understandable rationale

    3. Insufficient demonstration of knowledge base

    4. Lack of essential experience/expertise/ resources5. Diffuse, superficial or unfocused approach

    6. Interdependence of aims upon outcomes

    7. Unrealistic amount of work proposed

    8. Uncertain outcomes and future directions

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    You Do Not Want a Reviewer to Make This

    Comment About Your Application

    This application is characterized by ideas that

    are both original and scientifically important.

    Unfortunately, the ideas that are scientifically

    important are not original and the ideas thatare original are not scientifically important.

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    You Do Not Want a Reviewer to Make This

    Comment About Your Application

    In addition to proposing a research

    design that is a fishing expedition,

    the applicant also proposes to use

    every type of bait and piece of tackle

    ever known to mankind.

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    GRANT WRITERS SEMINARS

    AND WORKSHOPS

    THE FUNDAMENTALS OFGRANT WRITING

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    The Realities of Pursuing

    Grant Support

    Enthusiasm cannot bedirectlycommunicated to the grant agency.

    Ideas must first be transferred, therefore,to a written application.

    The application must then be screened andevaluated by a review panel.

    There are more good ideas than there areresources to support them.

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    Pathway to Grant Support

    The Applicant

    The Idea

    The Applicantion

    The Review Group

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    Characteristics of a

    Successful Grant-Writer

    Make a good first impression

    Is well-prepared

    Is credible

    Deliver a clear message

    Provides supporting documentation

    Has appropriate endorsements

    Has something special to offer

    Is persistent

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    Successful Grant-Writers

    Rule # 1

    DO NOT write the application for

    yourselfunless you are going to fundit yourself.

    You MUST convince the entire reviewcommittee and the funding agency.

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    Successful Grant-Writers

    Rule # 2

    STUDY SECTION DO NOT FUND !

    INSTITUTE FUNDS !

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    Successful Grant-Writers

    Rule # 3

    You must satisfy

    the needs of

    reviewers

    and the needs ofthe funding agency.

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    Who Are Your Reviewers?

    They are:

    Accomplished Dedicated

    Knowledgeable

    Conscientious Fair

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    Who Are Your Reviewers --

    Really?

    They are actually:

    Overly committed and over worked

    Underpaid for their efforts

    Tired

    Inherently skeptical Overly critical

    Looking for the easiest way to get

    the job done well

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    KEY POINT

    The primary key to achieving

    success in any grant applicationis to engender enthusiasm in thereviewerwho then becomes an

    advocate for the applicationsproposal.

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    What Do Reviewers

    Look for First?

    Whats the title? Is it interesting?

    Who is the applicant? Is the application complete?

    Have the directions been followed?

    Are there volumes of appendices? Is the application reviewer-friendly?

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    Is Your Application

    Reviewer-Friendly?

    KEY POINT

    While the guidelines specified aboveestablish the minimum type sizerequirements, PIs are advised thatreadability is of paramount importance and

    should take precedence in selection of anappropriate font for use in the proposal.

    NSF Instructions to Applicants, 2003

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    What Do Reviewers

    Look for Second?

    The key criteria that every grantapplicationmust address:

    Significance

    Approach

    Applicant

    Innovation

    Environment/Resources

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    Does Your Application

    Measure Up?

    SIGNIFICANCE

    Does this study address an importantproblem?

    If the aims of the application are

    achieved, will the field be advanced? How will the project contribute to the

    overall mission of the funding agency?

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    Does Your Application

    Measure Up?

    APPROACH/WORKPLAN

    Are the conceptual framework, design,

    methods, and analyses adequatelydeveloped, well-integrated, andappropriate?

    Is the completion schedule reasonable? Does the applicant acknowledge potential

    problem areas and consider alternativetactics?

    A i i

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    Does Your Application

    Measure Up?

    APPLICANT

    Is the applicant appropriately trained andwell-suited to carry out the work?

    Is the work proposed appropriate to the

    experience level of the applicant and

    other members of the team?

    Is the role of consultants or collaborators

    adequately justified?

    D Y A li i

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    Does Your Application

    Measure Up?

    ENVIRONMENT

    Does the environment in which the workwill be done contribute to theprobability of success?

    Do the proposed activities take advantage

    of unique features of the environment?

    What is the contribution of the sponsoring

    institution to the proposed work?

    D Y A li i

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    Does Your Application

    Measure Up?

    INNOVATION

    Does the project employ novelconcepts, approached, or methods?

    Are the aims original and innovative?

    Does the project challenge existing

    paradigms or develop new

    methodologies or techniques?

    Wh D R i

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    What Do Reviewers

    Look for Last?

    What singles outthis grant applicationfrom all others under consideration?

    WHY IS THIS GRANT SPECIAL

    AND, THEREFORE,DESERVING SUPPORT?

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    GRANT WRITERS SEMINARS

    AND WORKSHOPS

    TIP ONHOW TO WRITE

    FOR YOUR REVIEWERS

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    KEY POINTS

    For clarity of presentation, usesimple declarative sentences.

    Avoid complicated words, unusualabbreviations, and tortuous syntax.

    Avoid discontinuities in reading thatinterrupt concentration.

    Avoid weak words that convey doubt.

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    Abbreviations & Acronyms

    Keep the use of abbreviation and acronymsto a minimum.

    Overuse of these abbreviated wordforms is confusing and disruptive.

    Use only internationally-accepted

    abbreviations/acronyms. Try to avoid use of applicant-invented

    abbreviations/acronyms.

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    Weak Words

    Avoid weak words that may introducedoubt in the mind of the reviewersabout your ability to do the work.

    Example:

    We willtry to establish...vs.

    We expect to establish...

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    Weak Words

    Avoid weak words that may introducedoubt in the mind of the reviewersabout your ability to do the work.

    Example:

    Ifwe can demonstrate that...vs.

    We expect to demonstrate that...

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    Weak Words

    Avoid weak words that may introducedoubt in the mind of the reviewersabout your ability to do the work.

    Example:

    Webelieve that...vs.

    We expect that...

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    KEY POINTS - Continued

    Put the most important material up front;structure your presentation pyramidally.

    Use eye-catching headlines to convey yourmain points.

    Summarize the main points in an opening

    paragraph. Use new paragraphs to emphasize concepts

    and specific points and leavespaces

    between paragraphs.

    C t l St t f th

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    Conceptual Structure of the

    Ideal Grant Application

    IdeaSupporting

    Ideas, Concepts

    Details of the PlanAppendices

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    Use Informative Subheadings

    Example:Western Blot Analysis of VCAM Expression in

    Tumor Cells Following Transfection

    NOT

    Western Blot

    Example:Statistical Analysis of the Effectiveness of the

    Counseling Intervention

    NOT

    Data Analysis

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    Get Your Message Up Front

    Justice John Paul Stevens of the

    Supreme Court refusedtodelay an Illinois SupremeCourt rulinggiving custody of

    ababy boy to thebiologicalfather who hasnever seen him.

    W it As Th h F

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    Write As Though For

    a Newspaper

    REMEBER THAT PARAGRAPHS ARE:

    Arbitrary units designed to group information

    related to an idea or concept. Somewhat subjective as to what constitutes the

    functional unit.

    Basically under the control of the writer.

    Therefore, try to avoid excessively long orexcessively short paragraphs or sections.

    Three to four per page is ideal.