helpful allergic hypersensitivity ppt

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Page 1: Helpful Allergic Hypersensitivity PPT

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Fig 15Fig 15--1(2007; 161(2007; 16--1(2003)1(2003)

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xposurexposure

to allergento allergenPlasma cellsPlasma cells

produce IgEproduce IgE

IgE binds FcRIgE binds FcR

mastmast

22ndnd exposureexposure

to allergento allergenAllergenAllergen

crosslinkscrosslinksDegranulationDegranulation

of mastof mast

mastmast

cells/basophilscells/basophils

ce s asop sce s asop s

Release ofRelease of

mediators (causingmediators (causing

allergy symptoms)allergy symptoms)

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15-1 (2007)

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Table 16.3 Goldsby et al. 2003,

15-3 (2007)

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To et al., 2012

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Th2Various

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Kim et al., 2012. The

man arts to asthma . 

 Nat Immunol.

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Kim et al., 2012. The

man arts to asthma . 

 Nat Immunol.

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Kim et al., 2012. The

many parts to asthma .

a mmuno .

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Viswanathan and Busse, 2012

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