herbicidec919297.r97.cf2.rackcdn.com/72ftuniiidyf1x2zunrg9nanxcvk57-optimized-pub.pdfknow your...
TRANSCRIPT
Herbicide Classification Guide
i
HERBICIDE RESISTANCE: Take Action Against Herbicide ResistanceHerbicide resistance is here. And it’s going to take an industrywide effort to minimize it.
Which is why the soy checkoff has partnered with land-grant university weed scientists, ag chemical companies, various commodity groups and others to develop Take Action, a comprehensive herbicide-resistance weed-management program.
Take Action is a step-by-step approach of identifying weeds, understanding herbicides and implementing best weed-management practices.
This Herbicide Classification Guide is an important step in the program. By better knowing herbicides by their sites of action groups, you can diversify your herbicide programs to reduce your risk for herbicide resistance.
Take Action Before It Costs YouHerbicide resistance costs U.S. farmers an estimated $2 billion a year in decreased land values, decreased yields and increased input costs. And that figure is growing. So whether you have seen herbicide resistance or not, it is important to have a weed-management plan in place to prevent and control herbicide-resistant weeds.
Diversify Your PracticesEffective herbicide-resistance management is a balance of chemical and nonchemical management tactics to minimize the spread of herbicide- resistant weeds. To fight resistance in your fields, diversify your weed- management practices such as planting cover crops, incorporating tillage practices, managing field borders and cleaning equipment before moving to the next field.
Diversify Your Sites of ActionRepeated use of herbicides with the same site of action can lead to herbicide-resistant weed populations. This guide is developed to help you diversify the herbicide sites of action you use and create your own weed-management plan.
ii
Mode of Action vs. Site of ActionA MODE OF ACTION (MOA) describes the process within the plant that is inhibited by the herbicide. Another way to think of it is “how” the herbicide works. For example, amino acid inhibitors are a mode of action that disrupts the formation of amino acids.
A SITE OF ACTION (SOA) describes the physical location within the plant where the herbicide binds. This can also be thought of as “where” the herbicide works. For example, within the amino acid synthesis inhibitors mode of action, there are two different site-of-action groups. These are the ALS inhibitors and the EPSP synthase inhibitors (i.e., glyphosate). Herbicides within these two sites of action inhibit different enzymes within the weed.
Some farmers have been using different herbicides to add diversity to their weed management program and fight the development of resistance. However, it’s not enough to just use different herbicides. Farmers must ensure they are using effective herbicides with different sites of action, which offers actual diversity.
AN EXAMPLE:
This year a farmer chose to use a herbicide in the site of action group 2. In order to prevent herbicide resistance in his fields, the farmer should choose an effective herbicide in a different site-of-action group the next year, such as a herbicide in site-of-action group 10 or group 14.
It is important to note that the farmer could also use herbicides in group 9. While herbicide site-of-action groups 2 and 9 all have the same mode of action, they have different sites of action, which makes the herbicide effective because each site-of-action group targets a different enzyme.
Take Action with Sites of ActionHere is how you can Take Action against herbicide-resistant weeds and keep them from spreading.
Know your weeds. Understand what weeds are present in your fields and what options you have to control those weeds.
Know your herbicide site of action. Keep a running log of what herbicide products you sprayed last and their site- of-action groups.
Use multiple effective herbicide sites of action. Use this Herbicide Classification Guide to determine what other herbicide options you have to control those weeds that fall within a different site of action.
You can look up sites of action and the products that fall within that site of action or specific herbicides and premixes by product name.
• To look up a specific site of action, use the numbered list at the front of the guide.
• To look up a specific herbicide or premix, use the alphabetical listing in the back of the guide.
For more information on herbicide resistance, or to download a mobile version of this guide for your smartphone or tablet, visit www.TakeActionOnWeeds.com and check out the Site of Action Lookup Tool.
iii
ACCAse InhIbItors (acetyl CoA carboxylase)
ALs InhIbItors (acetolactate synthase)
MICrotubuLe InhIbItors
t1r1 AuXIn reCePtors(synthetic auxins)
PhotosysteM II InhIbItors(different binding than 6 & 7)
PhotosysteM II InhIbItors(different binding than 5 & 7)
PhotosysteM II InhIbItors (different binding than 5 & 6)
LIPId synthesIs InhIbItor(not ACCase)
ePsP synthAse InhIbItor (5-enolpyruvyl-shikimate-
3-phosphate)
GLutAMIne synthetAse InhIbItor
Phytoene desAturAse (Pds) InhIbItor
doXP synthAse InhIbItor (1-deoXy-d-XyuLose
5-PhosPhAte)
PPo InhIbItors
LonG-ChAIn fAtty ACId InhIbItors
sPeCIfIC sIte unknown
nuCLeIC ACId InhIbItor
AuXIn trAnsPort InhIbItor
PhotosysteM I eLeCtron dIverter
hPPd InhIbItors
by
sIte-of-ACtIon GrouP
by Site-o
f-Actio
n g
rou
p
This section groups herbicides by their sites of action to assist you in selecting herbicides 1) to maintain greater diversity in herbicide use and 2) to rotate among effective herbicides with different sites of action to delay the development of herbicide resistance.
1
ACCAse InhIbItors (acetyl CoA carboxylase)
MOA: Lipid Synthesis Inhibitors
Other Sites of Action within the same Mode of Action: None
Site of ActionS
ite-O
f-A
ct
iOn
Gr
Ou
p
1
ProductActive ingredient (Trade Name)
AdditionAl SoA
Assure II quizalofop
AxIAl sTArpinoxaden (Axial XL)
fluroxypyr (Starane) 4
AxIAl xl pinoxaden
ClInCher cyhalofop
DIsCover nG clodinafop
FoxFIrefenoxaprop (Tecoma)
pinoxaden (Axial XL)
FusIlADe Dx fluazifop
FusIon fluazifop (Fusilade DX)
fenoxaprop (Puma)
PoAsT sethoxydim
PoAsT Plus sethoxydim
rebelexcyhalofop (Clincher)
penoxsulam (Grasp) 2
rezulTbentazon (Basagran) 6
sethoxydim (Poast)
rICesTAr fenoxaprop
seleCT MAx clethodim
TArGA quizalofop
TeCoMA fenoxaprop
WolverIne
fenoxaprop (Tecoma)
pyrasulfotole 27
bromoxynil (Buctril) 6
1
1
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
Amazon sprangletop
Barnyardgrass
Downy brome (cheatgrass)
Giant foxtail
Giant green foxtail
Green foxtail
Italian ryegrass
Itchgrass
Johnsongrass
Large crabgrass
Late watergrass
Little seed canarygrass
Persian darnel
Smooth crabgrass
Wild oat
Accase inhibitors
The acetyl-coenzyme A carboxylase (ACCase)-inhibiting
herbicides include the cyclohexanedione, phenoxyproprionate
and phenylpyrazolin herbicides. These herbicides block the first
committed step in de novo fatty acid synthesis. The growth
of susceptible plants is halted, and plants gradually die because
of the absence of phospholipids for building new cell membranes.
resistant weed species in u.S. – 15
2
ALs InhIbItors (acetolactate synthase)
MOA: Amino Acid Synthesis Inhibitors
Other Sites of Action within the same Mode of Action: Group 9
Site of Action
2
ProductActive ingredient (Trade Name)
AdditionAl SoA
ACCenT Q nicosulfuron
ACColADe flumetsulam
AFFInITy broADsPeC(Affinity Tankmix)
thifensulfuron (Harmony)
tribenuron (Express)
AFForIA
thifensulfuron (Harmony)
tribenuron (Express)
flumioxazin (Valor) 14
AGIlITy sG
dicamba (Clarity) 4
thifensulfuron (Harmony)
tribenuron (Express)
metsulfuron (Ally)
Ally metsulfuron
Ally exTrA
thifensulfuron (Harmony)
tribenuron (Express)
metsulfuron (Ally)
AMber triasulfuron
AuThorITy AssIsTsulfentrazone (Spartan) 14
imazethapyr (Pursuit)
AuThorITy FIrsTsulfentrazone (Spartan) 14
cloransulam (FirstRate)
AuThorITy xl(Authority Maxx)
sulfentrazone (Spartan) 14
chlorimuron (Classic)
AuTuMn iodosulfuron
AuTuMn suPeriodosulfuron (Autumn)
thiencarbazone (Varro)
bAsIs blenDrimsulfuron (Resolve)
thifensulfuron (Harmony)
beACon primisulfuron
beyonD imazamox
CAnoPy chlorimuron (Classic)
metribuzin (Metribuzin) 5
Sit
e-O
f-A
ct
iOn
Gr
Ou
p22
3
CAnoPy exchlorimuron (Classic)
tribenuron (Express)
CAPrenothiencarbazone (Varro)
tembotrione (Laudis) 27
ClAssIC chlorimuron
CleArMAx imazamox
CleArPAThquinclorac (Facet) 4
imazethapyr (Newpath)
component of orIon florasulam
Corvusthiencarbazone (Varro)
isoxaflutole (Balance Flexx) 27
enlITe
chlorimuron (Classic)
thifensulfuron (Harmony)
flumioxazin (Valor) 14
envIve
chlorimuron (Classic)
thifensulfuron (Harmony)
flumioxazin (Valor) 14
envoke trifloxysulfuron
everesT flucarbazone
exPress tribenuron
exTreMe imazethapyr (Pursuit)
glyphosate (glyphosate) 9
FIerCe xlT
flumioxazin (Valor) 14
pyroxasulfone (Zidua) 15
chlorimuron (Classic)
FInesse chlorsulfuron (Glean)
metsulfuron (Ally)
FInesse GrAss AnD broADleAF
chlorsulfuron (Glean)
flucarbazone (Everest)
FIrsTrATe cloransulam
GAnGsTerflumioxazin (Valor) 14
cloransulam (FirstRate)
GleAn chlorsulfuron
GolDsky
pyroxsulam (PowerFlex HL)
florasulam
fluroxypyr (Starane) 4
GrAsP penoxsulam
hArMony thifensulfuron
horneT clopyralid (Stinger) 4
flumetsulam (Python)
2
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
ProductActive ingredient (Trade Name)
AdditionAl SoA
4
Huskie Complete
pyrasulfotole 27
bromoxynil (Buctril) 6
thiencarbazone (Varro)
instigaterimsulfuron (Resolve, Matrix)
mesotrione (Callisto) 27
leadoffrimsulfuron (Resolve)
thifensulfuron (Harmony)
londax bensulfuron
matrix rimsulfuron
maveriCk sulfosulfuron
newpatH imazethapyr
nortHstarprimisulfuron (Beacon)
dicamba (Clarity) 4
olympus propoxycarbazone
optillsaflufenacil (Sharpen) 14
imazethapyr (Pursuit)
optill pro
saflufenacil (Sharpen) 14
imazethapyr (Pursuit)
dimethenamid-p (Outlook) 15
orionflorasulam
mCpa (MCPA) 4
osprey mesosulfuron
panoflexthifensulfuron (Harmony)
tribenuron (Express)
peak prosulfuron
permit halosulfuron
permit plusthifensulfuron (Harmony)
halosulfuron (Permit)
plateau imazapic
powerflex Hl pyroxsulam
pre-pare flucarbazone
prequelrimsulfuron (Resolve)
isoxaflutole (Balance) 27
prioritycarfentrazone (Aim) 14
halosulfuron (Permit)
pursuit imazethapyr
pytHon flumetsulam
quelex*halauxifen 4
florasulam
raptor imazamox
2
Sit
e-o
f-A
ct
ion
Gr
ou
p
ProductActive ingredient (Trade Name)
AdditionAl SoA
5
ravetriasulfuron (Amber)
dicamba (Clarity) 4
razeflucarbazone (Everest)
fluroxypyr (Starane) 4
realm qrimsulfuron (Resolve)
mesotrione (Callisto) 27
rebelexcyhalofop (Clincher) 1
penoxsulam (Grasp)
regiment bispyribac
require qrimsulfuron (Resolve)
dicamba (Clarity) 4
resolve rimsulfuron
resolve qrimsulfuron (Resolve)
thifensulfuron (Harmony)
rimfire maxpropoxycarbazone (Olympus)
mesosulfuron (Osprey)
sCepter imazaquin
sierra flucarbazone
soniCsulfentrazone (Spartan) 14
cloransulam (FirstRate)
spiritprosulfuron (Peak)
primisulfuron (Beacon)
stanzaclopyralid (stinger) 4
flumetsulam (Python)
staple pyrithiobac
starane flexflorasulam
fluroxypyr (Starane) 4
steadfast qnicosulfuron (Accent Q)
rimsulfuron (Resolve)
strada orthosulfamuron
supremaCy
fluroxypyr (Starane) 4
thifensulfuron (Harmony)
tribenuron (Express)
suprendprometryn (Caparol) 5
trifloxysulfuron (Envoke)
surestart ii
acetochlor (Surpass) 15
clopyralid (Stinger) 4
flumetsulam (Python)
surveilflumioxazin (Valor) 14
cloransulam (FirstRate)
2 ProductActive ingredient (Trade Name)
AdditionAl SoA
Sit
e-o
f-A
ct
ion
Gr
ou
p
6
synCHrony chlorimuron (Classic)
thifensulfuron (Harmony)
tripleflex ii
acetochlor (Harness) 15
clopyralid (Stinger) 4
flumetsulam (Python)
trivenCe
chlorimuron (Classic)
flumioxazin (Valor) 14
metribuzin (Metribuzin) 5
upbeet triflusulfuron
valor xltflumioxazin (Valor) 14
chlorimuron (Classic)
varisito*imazamox (Raptor)
bentazon (Basagran) 6
varro thiencarbazone
yukondicamba (Banvel) 4
halosulfuron (Permit)
ProductActive ingredient (Trade Name)
AdditionAl SoA 2
Sit
e-o
f-A
ct
ion
Gr
ou
p
7
Sit
e-o
f-A
ct
ion
Gr
ou
p
2
resistant weed species in u.S. – 45
Annual bluegrass
Barnyardgrass
Bushy wallflower
California arrowhead
Cheat (rye brome)
Common chickweed
Common cocklebur
Common lambsquarters
Common ragweed
Common sunflower
Eared redstem
Eastern black nightshade
Flixweed
Giant foxtail
Giant ragweed
Green foxtail
Horseweed
Italian ryegrass
Japanese brome
Johnsongrass
Kochia
Livid amaranth
Marshelder
Mayweed chamomile
Palmer amaranth
Perennial ryegrass
Powell amaranth
Prickly lettuce
Prickly sida
Redroot pigweed
Redstem
Rice flatsedge
Ricefield bulrush
Russian thistle
Shattercane
Smallflower umbrella sedge
Smallseed flaxfalse
Smooth pigweed
Spiny sowthistle
Tall waterhemp
Variable flatsedge
Wild mustard
Wild oat
Yellow foxtail
Yellow nutsedge
ALS inhibitors
ALS inhibitors are also called acetohydroxy acid synthase
inhibitors. These herbicides are inhibitors of a common
enzyme leading to the synthesis of the branch-chain amino
acids leucine, valine and isoleucine. ALS inhibitors are used in
all of the major agronomic crops (i.e., corn, cotton, pastures,
peanut, small grains, soybean, turf and wheat) and typically
have residual activity. Symptoms of these herbicides include
growth cessation, internodal shortening, purple foliage and
shortened lateral roots (“bottle-brush” roots). Five herbicide
families constitute the ALS-inhibiting herbicides:
• sulfonylureas
• imidazolinones
• triazolopyrimidine sulfonanilides
• pyrimidinylthiobenzoic acids
• sulfonylaminocarbonyltriazolinones
8
MICrotubuLe InhIbItors MOA: Seedling Root Growth Inhibitors
Other Sites of Action within the same Mode of Action: None
Site of Action
3
ProductActive ingredient (Trade Name)
AdditionAl SoA
kerb pronamide
ProWl h2o pendimethalin
sonAlAn ethalfluralin
TreFlAn trifluralin
Sit
e-O
f-A
ct
iOn
Gr
Ou
p 3
9
Annual bluegrass
Goosegrass
Green foxtail
Johnsongrass
Palmer amaranth
Wild oat
3
Resistant weed species in U.S. – 6
Microtubule Inhibitors
Benzamide, dinitroaniline, phosphoramidate and pyridine
compounds are group 3 herbicides that bind to tubulin,
a major microtubule protein. The herbicide–tubulin complex
inhibits polymerization of microtubules at the assembly end
of the protein-based microtubule, leading to a loss of
microtubule structure and function, and cell wall formation
is negatively affected. Dinitroaniline herbicides are volatile,
readily dissipating into the atmosphere and, therefore,
often require soil incorporation (either disked into the soil
or through irrigation) for maximum efficacy.
SIt
e-o
f-A
ct
Ion
GR
oU
p
10
t1r1 AuXIn reCePtors(synthetic auxins)
MOA: Growth Regulators
Other Sites of Action within the same Mode of Action: Group 19
Site of Action
4
ProductActive ingredient (Trade Name)
AdditionAl SoA
2,4-D 2,4-D
AGIlITy sG
dicamba (Clarity)
thifensulfuron (Harmony) 2
tribenuron (Express) 2
metsulfuron (Ally) 2
AxIAl sTArpinoxaden (Axial XL) 1
fluroxypyr (Starane)
bAnvel dicamba
broADheADcarfentrazone (Aim) 14
quinclorac (Facet)
bronATebromoxynil (Buctril) 6
MCPA (MCPA)
CArnIvore
MCPA (MCPA)
clopyralid (Stinger)
bromoxynil (Buctril) 6
ClArITy dicamba
CleArPAThquinclorac (Facet)
imazethapyr (Newpath) 2
ColT + sAlvo(Trump Card)
2,4-D (2,4-D)
fluroxypyr (Starane)
ColT + sWorDMCPA (MCPA)
fluroxypyr (Starane)
component of Quelex* halauxifen
CurTAIlclopyralid (Stinger)
2,4-D (2,4-D)
CurTAIl Mclopyralid (Stinger)
MCPA (MCPA)
DIFlexx* dicamba
enlIsT Duo2,4-D (2,4-D)
glyphosate (glyphosate) 9
FACeT quinclorac
4
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
11
GolDsky
pyroxsulam (PowerFlex HL) 2
florasulam 2
fluroxypyr (Starane)
GrAnDsTAnD triclopyr
horneTclopyralid (Stinger)
flumetsulam (Python) 2
MArksMAndicamba (Clarity)
atrazine (AAtrex) 5
MCPA MCPA
norThsTArprimisulfuron (Beacon) 2
dicamba (Clarity)
obeyclomazone (Command) 13
quinclorac (Facet)
orIonflorasulam 2
MCPA (MCPA)
PArAMounT quinclorac
PulsArdicamba (Clarity)
fluroxypyr (Starane)
Quelex*halauxifen
florasulam 2
rAvetriasulfuron (Amber) 2
dicamba (Clarity)
rAzeflucarbazone (Everest) 2
fluroxypyr (Starane)
reQuIre Qrimsulfuron (Resolve) 2
dicamba (Clarity)
shoTGunatrazine (AAtrex) 5
2,4-D (2,4-D)
sTAnzAclopyralid (Stinger)
flumetsulam (Python) 2
sTArAne fluroxypyr
sTArAne Flexflorasulam 2
fluroxypyr (Starane)
sTArAne nxTfluroxypyr (Starane)
bromoxynil (Buctril) 6
sTATusdiflufenzopyr 19
dicamba (Clarity)
sTInGer clopyralid
suPreMACy
fluroxypyr (Starane)
thifensulfuron (Harmony) 2
tribenuron (Express) 2
4 ProductActive ingredient (Trade Name)
AdditionAl SoA
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
12
surestart ii
acetochlor (Surpass) 15
clopyralid (Stinger)
flumetsulam (Python) 2
tripleflex ii
acetochlor (Harness) 15
clopyralid (Stinger)
flumetsulam (Python) 2
weld (full deCk)
mCpa (MCPA)
fluroxypyr (Starane)
clopyralid (Stinger)
widematCHclopyralid (Stinger)
fluroxypyr (Starane)
yukondicamba (Banvel)
halosulfuron (Permit) 2
4ProductActive ingredient (Trade Name)
AdditionAl SoA
Sit
e-o
f-A
ct
ion
Gr
ou
p
13
4
Sit
e-o
f-A
ct
ion
Gr
ou
p
Barnyardgrass
Kochia
Prickly lettuce
Smooth crabgrass
Spreading dayflower
Tall waterhemp
Wild carrot
Yellow starthistle
resistant weed species in u.S. – 8
t1r1 Auxin receptors
The benzoic acids, phenoxycarboxylic acids, pyridine carboxylic
acids and quinoline carboxylic acids collectively form the group
of synthetic auxin herbicides. Herbicides in this group have
activity similar to that of endogenous auxin, although the
true mechanism is not well understood. Symptoms include
abnormal growth and eventual plant death. The oldest
selective herbicide, 2,4-D, is categorized in this group.
14
PhotosysteM II InhIbItors(different binding than 6 & 7)
MOA: Photosynthesis Inhibitors
Other Sites of Action within the same Mode of Action: Group 6, Group 7
Site of Action
5
ProductActive ingredient (Trade Name)
AdditionAl SoA
AATrex atrazine
ACuron*
bicyclopyrone 27
mesotrione (Callisto) 27
atrazine (AAtrex)
s-metolachlor (Dual Magnum) 15
AnTheM ATz
pyroxasulfone (Zidua) 15
fluthiacet (Cadet) 14
atrazine (AAtrex)
AuThorITy MTzsulfentrazone (Spartan) 14
metribuzin (Metribuzin)
beTAMIxdesmedipham (Betenex)
phenmedipham
beTenex desmedipham
bICeP II MAGnuM(bicep lite II Magnum)
s-metolachlor (Dual II Magnum) 15
atrazine (AAtrex)
bounDAry
s-metolachlor (Dual Magnum) 15
metribuzin (Metribuzin)
breAkFree nxT ATz(breakfree nxT lite)
acetochlor (Breakfree NXT) 15
atrazine (AAtrex)
bulleTalachlor (Micro-Tech) 15
atrazine (AAtrex)
CAllIsTo xTrAmesotrione (Callisto) 27
atrazine (AAtrex)
CAnoPychlorimuron (Classic) 2
metribuzin (Metribuzin)
CAPArol prometryn
CInCh ATz(Cinch ATz lite)
s-metolachlor (Dual II Magnum) 15
atrazine (AAtrex)
component of beTAMIx phenmedipham
5
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
15
DeGree xTrAacetochlor (Degree) 15
atrazine (AAtrex)
exPerT
s-metolachlor (Dual Magnum) 15
atrazine (AAtrex)
glyphosate (glyphosate) 9
FIelD MAsTer
acetochlor (Harness) 15
atrazine (AAtrex)
glyphosate (glyphosate) 9
FulTIMe nxTacetochlor (TopNotch) 15
atrazine (AAtrex)
GuArDsMAn MAx(G-Max lite)
dimethenamid-P (Outlook) 15
atrazine (AAtrex)
hArness xTrAacetochlor (Harness) 15
atrazine (AAtrex)
keysTone nxT(keystone lA nxT)
acetochlor (Surpass NXT) 15
atrazine (AAtrex)
lexAr ez
mesotrione (Callisto) 27
s-metolachlor (Dual II Magnum) 15
atrazine (AAtrex)
luMAx ez
mesotrione (Callisto) 27
s-metolachlor (Dual II Magnum) 15
atrazine (AAtrex)
MArksMAndicamba (Clarity) 4
atrazine (AAtrex)
MeTrIbuzIn metribuzin
PrInCeP simazine
ProGress
desmedipham (Betenex)
phenmedipham
ethofumesate (Nortron) 16
shoTGunatrazine (AAtrex)
2,4-D (2,4-D) 4
sInbAr terbacil
suPrenDprometryn (Caparol)
trifloxysulfuron (Envoke) 2
TrIvenCe
chlorimuron (Classic) 2
flumioxazin (Valor) 14
metribuzin (metribuzin)
velPAr hexazinone
velPAr AlFAMAxhexazinone (Velpar)
diuron (Karmex) 7
5 ProductActive ingredient (Trade Name)
AdditionAl SoA
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
16
5
Sit
e-o
f-A
ct
ion
Gr
ou
p
17
5
Sit
e-o
f-A
ct
ion
Gr
ou
p
Annual bluegrass
Barnyardgrass
Common groundsel
Common lambsquarters
Common purslane
Common ragweed
Eastern black nightshade
Giant foxtail
Goosegrass
Halberdleaf orach
Horseweed
Jimsonweed
Kochia
Ladysthumb
Lateflowering goosefoot
Palmer amaranth
Pennsylvania smartweed
Powell amaranth
Prostrate pigweed
Redroot pigweed
Shepherd’s-purse
Smooth pigweed
Swollen fingergrass
Tall waterhemp
Velvetleaf
Yellow foxtail
resistant weed species in u.S. – 26
photosystem ii inhibitors
The phenylcarbamates, pyridazinones, triazines, triazinones
and uracils (group 5) include herbicides that inhibit photosyn-
thesis by binding to the QB-binding niche of the D1 protein
of the photosystem II complex in chloroplast thylakoid
membranes. While having the same mode of action as groups 6
and 7, group 5 herbicides bind in a different QB-binding site
of action. Herbicide binding in this site negatively affects
processes and products necessary for the transport of
chemical energy. Death in susceptible plants generally occurs
via cell membrane disintegration because of the creation of
triplet state chlorophyll, singlet oxygen and lipid peroxidation.
18
PhotosysteM II InhIbItors (different binding than 5 & 7)
MOA: Photosynthesis Inhibitors
Other Sites of Action within the same Mode of Action: Group 5, Group 7
Site of Action
6
ProductActive ingredient (Trade Name)
AdditionAl SoA
bAsAGrAn bentazon
bronATebromoxynil (Buctril)
MCPA (MCPA) 4
buCTrIl bromoxynil
CArnIvore
MCPA (MCPA) 4
clopyralid (Stinger) 4
bromoxynil (Buctril)
huskIepyrasulfotole 27
bromoxynil (Buctril)
huskIe CoMPleTe
pyrasulfotole 27
bromoxynil (Buctril)
thiencarbazone (Varro) 2
rezulTbentazon (Basagran)
sethoxydim (Poast) 1
sTArAne nxTfluroxypyr (Starane) 4
bromoxynil (Buctril)
sTorMbentazon (Basagran)
acifluorfen (Ultra Blazer) 14
vArIsITo*imazamox (Raptor) 2
bentazon (Basagran)
WolverIne
fenoxaprop (Tecoma) 1
pyrasulfotole 27
bromoxynil (Buctril)
6
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
19
6
Common groundsel
resistant weed species in u.S. – 1
photosystem ii inhibitors
The benzothiadiazinones, nitriles and phenylpyridazines
(group 6) include herbicides that inhibit photosynthesis
by binding to the QB-binding niche of the D1 protein of the
photosystem II complex in chloroplast thylakoid membranes.
While having the same mode of action as groups 5 and 7,
group 6 herbicides bind in a different QB-binding site of action.
Herbicide binding in this site negatively affects processes
and products necessary for the transport of chemical energy.
Death in susceptible plants generally occurs via cell membrane
disintegration because of the creation of triplet state
chlorophyll, singlet oxygen and lipid peroxidation.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
20
PhotosysteM II InhIbItors (different binding than 5 & 6)
MOA: Photosynthesis Inhibitors
Other Sites of Action within the same Mode of Action: Group 5, Group 6
Site of Action
7
ProductActive ingredient (Trade Name)
AdditionAl SoA
CoTorAn fluometuron
DIrex diuron
kArMex diuron
lInex linuron
lorox linuron
suPerWhAM propanil
velPAr AlFAMAxhexazinone (Velpar) 5
diuron (Karmex)
7
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
21
7
Annual bluegrass
Barnyardgrass
Common purslane
Horseweed
Powell amaranth
Redroot pigweed
Ricefield bulrush
Smallflower umbrella sedge
Swollen fingergrass
resistant weed species in u.S. – 9
photosystem ii inhibitors
The amides and ureas (group 7) include herbicides that
inhibit photosynthesis by binding to the QB-binding niche
of the D1 protein of the photosystem II complex in chloroplast
thylakoid membranes. While having the same mode of action
as groups 5 and 6, group 7 herbicides bind in a different
QB-binding site of action. Herbicide binding in this site
negatively affects processes and products necessary for
the transport of chemical energy. Death in susceptible plants
generally occurs via cell membrane disintegration because
of the creation of triplet state chlorophyll, singlet oxygen
and lipid peroxidation.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
22
LIPId synthesIs InhIbItor (not ACCase)
MOA: Seedling Shoot Growth Inhibitors
Other Sites of Action within the same Mode of Action: Group 15, Group 16
Site of Action
8
ProductActive ingredient (Trade Name)
AdditionAl SoA
bolero thiobencarb
ePTAM ePTC
erADICAne ePTC
FAr-Go triallate
ro-neeT cycloate
suTAn + butylate
8
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
23
8
Annual bluegrass
Barnyardgrass
Early watergrass
Late watergrass
Wild oat
resistant weed species in u.S. – 5
Lipid Synthesis inhibitor
The phosphorodithioates and thiocarbamates (group 8) are
herbicides known to inhibit several plant processes, including
biosynthesis of fatty acids and lipids, proteins, isoprenoids,
flavonoids and gibberellins. It is currently thought that these
effects may be linked by the conjugation of acetyl-coenzyme A
and other sulfhydryl-containing molecules by thiocarbamate
sulfoxides. Herbicides with this MOA may be referred to as
the lipid and secondary biosynthesis inhibitors. To maximize
efficacy in controlling weeds, thiocarbamates are typically
incorporated into the soil. Seedlings of susceptible weed
species fail to emerge, and phytotoxic symptoms are
characterized by tightly whorled leaves that do not unroll
in a normal fashion.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
24
ePsP synthAse InhIbItor (5-enolpyruvyl-shikimate-3-phosphate)
MOA: Amino Acid Synthesis Inhibitors
Other Sites of Action within the same Mode of Action: Group 2
Site of Action
9
ProductActive ingredient (Trade Name)
AdditionAl SoA
CAllIsTo GTmesotrione (Callisto) 27
glyphosate (glyphosate)
enlIsT Duo2,4-D (2,4-D) 4
glyphosate (glyphosate)
exPerT
s-metolachlor (Dual Magnum) 15
atrazine (AAtrex) 5
glyphosate (glyphosate)
exTreMeimazethapyr (Pursuit) 2
glyphosate (glyphosate)
FIelD MAsTer
acetochlor (Harness) 15
atrazine (AAtrex) 5
glyphosate (glyphosate)
FlexsTAr GTfomesafen (Flexstar) 14
glyphosate (glyphosate)
hAlex GT
s-metolachlor (Dual Magnum) 15
mesotrione (Callisto) 27
glyphosate (glyphosate)
rounDuP glyphosate
seQuenCe
s-metolachlor (Dual Magnum) 15
glyphosate (glyphosate)
TouChDoWn glyphosate
9
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
25
9
Annual bluegrass
Common ragweed
Giant ragweed
Goosegrass
Hairy fleabane
Horseweed
Italian ryegrass
Johnsongrass
Junglerice
Kochia
Palmer amaranth
Rigid ryegrass
Spiny amaranth
Tall waterhemp
resistant weed species in u.S. – 14
epSp Synthase inhibitor
Group 9, the glycines, includes only glyphosate. Glyphosate
inhibits enolpyruvyl shikimate-3-phosphate synthase (EPSPS),
which leads to depletion of the aromatic amino acids
tryptophan, tyrosine and phenylalanine, all needed for protein
synthesis or for biosynthetic pathways leading to growth.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
26
GLutAMIne synthetAse InhIbItorMOA: Nitrogen Metabolism Inhibitor
Other Sites of Action within the same Mode of Action: None
Site of Action
10
ProductActive ingredient (Trade Name)
AdditionAl SoA
lIberTy glufosinate
10
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
27
10
Italian ryegrass
resistant weed species in u.S. – 1
Glutamine Synthetase inhibitor
Herbicides in group 10 are glufosinate and bialaphos,
the phosphinic acids. They inhibit the activity of glutamine
synthetase, the enzyme that converts glutamate and
ammonia to glutamine. Accumulation of ammonia in the
plant destroys cells and directly inhibits photosystem I
and photosystem II reactions. Ammonia also reduces
the pH gradient across the membrane that can uncouple
photophosphorylation.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
28
Phytoene desAturAse (Pds) InhIbItor MOA: Pigment Inhibitor
Other Sites of Action within the same Mode of Action: Group 13, Group 27
Site of Action
12
ProductActive ingredient (Trade Name)
AdditionAl SoA
brAke F2fomesafen (Flexstar) 14
fluridone (Sonar)
sonAr fluridone
12
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
29
12
Hydrilla
resistant weed species in u.S. – 1
phytoene Desaturase (pDS) inhibitor
Herbicides in group 12 include the amides, anilidex, furanones,
pheno`xybutan-amides, pyridazinones and pyridines that
block carotenoid synthesis by inhibition of phytoene
desaturase. Carotenoids play an important role in dissipating
the oxidative energy of singlet oxygen and other radicals.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
30
doXP synthAse InhIbItor (1-deoxy-d-xyulose 5-phosphate)
MOA: Pigment Inhibitors
Other Sites of Action within the same Mode of Action: Group 12, Group 27
Site of Action
13
ProductActive ingredient (Trade Name)
AdditionAl SoA
CoMMAnD clomazone
obeyclomazone (Command)
quinclorac (Facet) 4
13
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
31
13
Barnyardgrass
Resistant weed species in U.S. – 1
DoXp Synthase Inhibitor
Clomazone (group 13) is metabolized to the 5-keto form of
clomazone that is herbicidally active. The 5-keto form inhibits
1-deoxy-D-xylulose 5-phosphate synthase, a key component
of plastid isoprenoid synthesis for production of carotenoids.
SIt
e-o
f-A
ct
Ion
GR
oU
p
32
PPo InhIbItorsMOA: Cell Membrane Disrupters
Other Sites of Action within the same Mode of Action: Group 22
Site of Action
14
ProductActive ingredient (Trade Name)
AdditionAl SoA
AFForIA
thifensulfuron (Harmony) 2
tribenuron (Express) 2
flumioxazin (Valor)
AIM carfentrazone
AnTheMpyroxasulfone (Zidua) 15
fluthiacet (Cadet)
AnTheM ATz
pyroxasulfone (Zidua) 15
fluthiacet (Cadet)
atrazine (AAtrex) 5
AnTheM Flexpyroxasulfone (Zidua) 15
carfentrazone (Aim)
AuThorITy AssIsTsulfentrazone (Spartan)
imazethapyr (Pursuit) 2
AuThorITy elITesulfentrazone (Spartan)
s-metolachlor (Dual Magnum) 15
AuThorITy FIrsTsulfentrazone (Spartan)
cloransulam (FirstRate) 2
AuThorITy MTzsulfentrazone (Spartan)
metribuzin (Metribuzin) 5
AuThorITy xl(Authority Maxx)
sulfentrazone (Spartan)
chlorimuron (Classic) 2
brAke F2fomesafen (Flexstar)
fluridone (Sonar) 12
broADAxe
s-metolachlor (Dual Magnum) 15
sulfentrazone (Spartan)
broADheADcarfentrazone (Aim)
quinclorac (Facet) 4
CADeT fluthiacet
CobrA lactofen
14
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
33
enlITe
chlorimuron (Classic) 2
thifensulfuron (Harmony) 2
flumioxazin (Valor)
envIve
chlorimuron (Classic) 2
thifensulfuron (Harmony) 2
flumioxazin (Valor)
FIerCeflumioxazin (Valor)
pyroxasulfone (Zidua) 15
FIerCe xlT
flumioxazin (Valor)
pyroxasulfone (Zidua) 15
chlorimuron (Classic) 2
FlexsTAr fomesafen
FlexsTAr GTfomesafen (Flexstar)
glyphosate (glyphosate) 9
GAnGsTerflumioxazin (Valor)
cloransulam (FirstRate) 2
MArvelfluthiacet (Cadet)
fomesafen (Flexstar)
oPTIllsaflufenacil (Sharpen)
imazethapyr (Pursuit) 2
oPTIll Pro
saflufenacil (Sharpen)
imazethapyr (Pursuit) 2
dimethenamid-P (Outlook) 15
PhoenIx lactofen
PreFIx
s-metolachlor (Dual Magnum) 15
fomesafen (Reflex)
PrIorITycarfentrazone (Aim)
halosulfuron (Permit) 2
reFlex fomesafen
resourCe flumiclorac
shArPen saflufenacil
solsTICemesotrione (Callisto) 27
fluthiacet (Cadet)
sonICsulfentrazone (Spartan)
cloransulam (FirstRate) 2
sPArTAn sulfentrazone
sPArTAn ChArGesulfentrazone (Spartan)
carfentrazone (Aim)
sTorMbentazon (Basagran)
acifluorfen (Ultra Blazer)
14 ProductActive ingredient (Trade Name)
AdditionAl SoA
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
34
14
Sit
e-o
f-A
ct
ion
Gr
ou
p
surveilflumioxazin (Valor)
cloransulam (FirstRate) 2
trivenCe
chlorimuron (Classic) 2
flumioxazin (Valor)
metribuzin (metribuzin) 5
ultra blazer acifluorfen
valor flumioxazin
valor xltflumioxazin (Valor)
chlorimuron (Classic) 2
verdiCtsaflufenacil (Sharpen)
dimethenamid-p (Outlook) 15
ProductActive ingredient (Trade Name)
AdditionAl SoA
35
14
Sit
e-o
f-A
ct
ion
Gr
ou
p
Common ragweed Tall waterhemp
resistant weed species in u.S. – 2
ppo inhibitors
These chlorophyll synthesis inhibitors (PPO-inhibitors)
comprise several herbicide families: the diphenylethers
(e.g., fomesafen), N-phenylphthalimides (e.g., flumioxazin),
oxadiazoles (e.g., oxadiargyl), oxazolidinediones, phenylpyrazoles
(e.g., flufenpyr-ethyl), pyrimidindiones (e.g., butafenacil),
thiadiazoles and triazolinones (e.g., azafenidin, sulfentrazone).
Herbicides in this category inhibit protoporphyrinogen oxidase
(PPG oxidase or Protox), an enzyme involved in chlorophyll
and heme synthesis. Inhibition leads to an accumulation of PPIX,
the first light-absorbing chlorophyll precursor. Light absorption
by PPIX apparently produces triplet state PPIX that interacts
with ground state oxygen to form singlet oxygen. Triplet PPIX
and singlet oxygen lead to the formation of lipid radicals
that initiate a chain reaction of lipid peroxidation and cause
cellular leakage and plant death.
36
LonG-ChAIn fAtty ACId InhIbItorsMOA: Seedling Shoot Growth Inhibitors
Other Sites of Action within the same Mode of Action: Group 8, Group 16
Site of Action
15
ProductActive ingredient (Trade Name)
AdditionAl SoA
ACuron*
bicyclopyrone 27
mesotrione (Callisto) 27
atrazine (AAtrex) 5
s-metolachlor (Dual Magnum)
AnTheMpyroxasulfone (Zidua)
fluthiacet (Cadet) 14
AnTheM ATz
pyroxasulfone (Zidua)
fluthiacet (Cadet) 14
atrazine (AAtrex) 5
AnTheM Flexpyroxasulfone (Zidua)
carfentrazone (Aim) 14
AuThorITy elITesulfentrazone (Spartan) 14
s-metolachlor (Dual Magnum)
bICeP II MAGnuM(bicep lite II Magnum)
s-metolachlor (Dual Magnum)
atrazine (AAtrex) 5
bounDAry
s-metolachlor (Dual Magnum)
metribuzin (Metribuzin) 5
breAkFree nxT ATz(breakfree nxT lite)
acetochlor (Breakfree NXT)
atrazine (AAtrex) 5
broADAxe
metolachlor (Dual Magnum)
sulfentrazone (Spartan) 14
bulleTalachlor (Micro-Tech)
atrazine (AAtrex) 5
CInCh ATz(Cinch ATz lite)
s-metolachlor (Dual Magnum)
atrazine (AAtrex) 5
DeFIne flufenacet
DeGree acetochlor
15
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
37
Degree Xtraacetochlor (Degree)
atrazine (AAtrex) 5
Dual MagnuM s-metolachlor
eXpert
s-metolachlor (Dual Magnum)
atrazine (AAtrex) 5
glyphosate (glyphosate) 9
FielD Master
acetochlor (Harness)
atrazine (AAtrex) 5
glyphosate (glyphosate) 9
Fierceflumioxazin (Valor) 14
pyroxasulfone (Zidua)
Fierce Xlt
flumioxazin (Valor) 14
pyroxasulfone (Zidua)
chlorimuron (Classic) 2
FultiMe nXtacetochlor (TopNotch)
atrazine (AAtrex) 5
guarDsMan MaX (g-Max lite)
dimethenamid-p (Outlook)
atrazine (AAtrex) 5
HaleX gt
s-metolachlor (Dual Magnum)
mesotrione (Callisto) 27
glyphosate (glyphosate) 9
Harness acetochlor
Harness Xtraacetochlor (Harness)
atrazine (AAtrex) 5
intrro alachlor
Keystone nXt(Keystone la nXt)
acetochlor (Surpass NXT) x
atrazine (AAtrex) 5
leXar eZ
mesotrione (Callisto) 27
s-metolachlor (Dual Magnum)
atrazine (AAtrex) 5
luMaX eZ
mesotrione (Callisto) 27
s-metolachlor (Dual Magnum)
atrazine (AAtrex) 5
Micro-tecH alachlor
optill pro
saflufenacil (Sharpen) 14
imazethapyr (Pursuit) 2
dimethenamid-p (Outlook)
outlooK dimethenamid-p
15 ProductActive ingredient (Trade Name)
AdditionAl SoA
SIt
e-o
f-A
ct
Ion
GR
oU
p
38
prefix
s-metolachlor (Dual Magnum)
fomesafen (Reflex) 14
sequenCe
s-metolachlor (Dual Magnum)
glyphosate (glyphosate) 9
surestart ii
acetochlor (Surpass)
clopyralid (Stinger) 4
flumetsulam (Python) 2
surpass nxt acetochlor
topnotCH acetochlor
tripleflex ii
acetochlor (Harness)
clopyralid (Stinger) 4
flumetsulam (Python) 2
verdiCtsaflufenacil (Sharpen) 14
dimethenamid-p (Outlook)
warrant acetochlor
zemaxmesotrione (Callisto) 27
s-metolachlor (Dual Magnum)
zidua pyroxasulfone
15ProductActive ingredient (Trade Name)
AdditionAl SoA
Sit
e-o
f-A
ct
ion
Gr
ou
p
39
15
Sit
e-o
f-A
ct
ion
Gr
ou
p
Italian ryegrass
resistant weed species in u.S. – 1
Long-chain fatty Acid inhibitors
Acetamide, chloroacetamide, oxyacetamide and tetrazolinone
compounds are group 15 herbicides that are thought to inhibit
very long-chain fatty acid synthesis. These compounds affect
susceptible weeds before emergence but do not inhibit
seed germination.
40
sPeCIfIC sIte unknown MOA: Seedling Shoot Growth Inhibitors
Other Sites of Action within the same Mode of Action: Group 8, Group 15
Site of Action
1616
ProductActive ingredient (Trade Name)
AdditionAl SoA
norTron ethofumesate
ProGress
desmedipham (Betenex) 5
phenmedipham 5
ethofumesate (Nortron)
16
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
41
16
resistant weed species in u.S. – 0
Specific Site unknown
The benzofuranes (group 16) are herbicides known to inhibit
several plant processes, including biosynthesis of fatty acids
and lipids, proteins, isoprenoids, flavonoids and gibberellins.
It is currently thought that these effects may be linked by
the conjugation of acetyl-coenzyme A and other sulfhydryl-
containing molecules by thiocarbamate sulfoxides. Herbicides
with this MOA may be referred to as the lipid and secondary
biosynthesis inhibitors. To maximize efficacy in controlling
weeds, thiocarbamates are typically incorporated into the
soil. Seedlings of susceptible weed species fail to emerge,
and phytotoxic symptoms are characterized by tightly
whorled leaves that do not unroll in a normal fashion.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
42
nuCLeIC ACId InhIbItorMOA: Undefined
Other Sites of Action within the same Mode of Action: None
Site of Action
17
ProductActive ingredient (Trade Name)
AdditionAl SoA
MsMA MsMA
17
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
43
17
Common cocklebur
Resistant weed species in U.S. – 1
nucleic Acid Inhibitor
Herbicides in group 17 have an unknown MOA.S
Ite-o
f-A
ct
Ion
GR
oU
p
44
AuXIn trAnsPort InhIbItorMOA: Growth Regulators
Other Sites of Action within the same Mode of Action: Group 4
Site of Action
19
ProductActive ingredient (Trade Name)
AdditionAl SoA
component of sTATus diflufenzopyr
sTATusdiflufenzopyr
dicamba (Clarity) 4
19
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
45
19
resistant weed species in u.S. – 0
Auxin transport inhibitor
The phthalamates (e.g., naptalam) and semicarbazones
(e.g., diflufenzopyr) are group 19 herbicides. These herbicides
inhibit polar transport of naturally occurring auxin, indoleacetic
acid and synthetic auxin-mimicking herbicides in sensitive
plants. Auxin-transport inhibition causes an abnormal
accumulation of auxin in the meristematic regions, thereby
disrupting the auxin balance needed for plant growth.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
46
PhotosysteM I eLeCtron dIverterMOA: Cell Membrane Disrupters
Other Sites of Action within the same Mode of Action: Group 14
Site of Action
22
ProductActive ingredient (Trade Name)
AdditionAl SoA
GrAMoxone sl paraquat
reGlone diquat
22
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
47
22
American black nightshade
Dotted duckweed
Goosegrass
Hairy fleabane
Horseweed
resistant weed species in u.S. – 5
photosystem i electron Diverter
The bipyridyliums (e.g., paraquat, diquat) are examples
of herbicides that accept electrons from photosystem I
and reduce them to form a herbicide radical. The radical
then reduces molecular oxygen to form superoxide radicals.
The superoxide radicals lead to the formation of hydrogen
peroxide and hydroxy radicals that destroy lipid membrane
fatty acids and chlorophyll, thereby causing membrane
destruction, cellular leakage and a very rapid plant death
in sunlight.
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
48
hPPd InhIbItorsMOA: Pigment Inhibitors
Other Sites of Action within the same Mode of Action: Group 12, Group 13
Site of Action
27
ProductActive ingredient (Trade Name)
AdditionAl SoA
ACuron*
bicyclopyrone
mesotrione (Callisto)
atrazine (AAtrex) 5
s-metolachlor (Dual Magnum) 15
ArMezon topramezone
bAlAnCe Flexx isoxaflutole
CAllIsTo mesotrione
CAllIsTo GTmesotrione (Callisto)
glyphosate (glyphosate) 9
CAllIsTo xTrAmesotrione (Callisto)
atrazine (AAtrex) 5
CAPrenothiencarbazone (Varro) 2
tembotrione (Laudis)
component of ACuron* bicyclopyrone
component of huskIe pyrasulfotole
Corvusthiencarbazone (Varro) 2
isoxaflutole (Balance Flexx)
hAlex GT
s-metolachlor (Dual Magnum) 15
mesotrione (Callisto)
glyphosate (glyphosate) 9
huskIepyrasulfotole
bromoxynil (Buctril) 6
huskIe CoMPleTe
pyrasulfotole
bromoxynil (Buctril) 6
thiencarbazone (Varro) 2
IMPACT topramezone
InsTIGATe
rimsulfuron (Resolve, Matrix) 2
mesotrione (Callisto)
lAuDIs tembotrione
27
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
49
by Pro
du
ct
lexAr ez
mesotrione (Callisto)
s-metolachlor (Dual II Magnum) 15
atrazine (AAtrex) 5
luMAx ez
mesotrione (Callisto)
s-metolachlor (Dual II Magnum) 15
atrazine (AAtrex) 5
PreQuelrimsulfuron (Resolve) 2
isoxaflutole (Balance)
reAlM Qrimsulfuron (Resolve) 2
mesotrione (Callisto)
solsTICemesotrione (Callisto)
fluthiacet (Cadet) 14
WolverIne
fenoxaprop (Tecoma) 1
pyrasulfotole
bromoxynil (Buctril) 6
zeMAxmesotrione (Callisto)
s-metolachlor (Dual II Magnum) 15
27
Sit
e-O
f-A
ct
iOn
Gr
Ou
p
ProductActive ingredient (Trade Name)
AdditionAl SoA
Palmer amaranth Tall waterhemp
resistant weed species in u.S. – 2
HppD inhibitors
Callistemon, isoxazole, pyrazole and triketone herbicides (group 27) inhibit a key step in plastoquinone biosynthesis; its inhibition gives rise to bleaching symptoms on new growth. symptoms on plants result from an indirect inhibition of carotenoid synthesis because of the involvement of plastoquinone as a cofactor of phytoene desaturase.
50
by Pro
du
ct
by
product
51
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
2,4-D 2,4-D
AAtrex atrazine 5
Accent Q nicosulfuron
AccolADe flumetsulam 2
Acuron*
bicyclopyrone
mesotrione (Callisto)
atrazine (AAtrex)
s-metolachlor (Dual Magnum)
Affinity BroADSpec(Affinity tankmix)
thifensulfuron (Harmony) 2
tribenuron (Express) 2
AfforiA
thifensulfuron (Harmony)
tribenuron (Express)
flumioxazin (Valor))
Agility Sg
dicamba (Clarity) 4
thifensulfuron (Harmony) 2
tribenuron (Express) 2
metsulfuron (Ally) 2
Aim carfentrazone
Ally metsulfuron 2
Ally extrA
thifensulfuron (Harmony)
tribenuron (Express)
metsulfuron (Ally)
AmBer triasulfuron 2
Anthempyroxasulfone (Zidua)
fluthiacet (Cadet)
Anthem AtZ
pyroxasulfone (Zidua) 15
fluthiacet (Cadet) 14
atrazine (AAtrex) 5
Anthem flexpyroxasulfone (Zidua)
carfentrazone (Aim)
ArmeZon topramezone 27
ASSure ii quizalofop
Authority ASSiStsulfentrazone (Spartan) 14
imazethapyr (Pursuit) 2
Authority elitesulfentrazone (Spartan)
s-metolachlor (Dual Magnum)
Authority firStsulfentrazone (Spartan) 14
cloransulam (FirstRate) 2
Product Active ingredient (Trade Name)
Site of Action
53
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
Authority mtZsulfentrazone (Spartan)
metribuzin (Metribuzin)
Authority xl(Authority maxx)
sulfentrazone (Spartan) 14
chlorimuron (Classic) 2
Autumn iodosulfuron
Autumn Superiodosulfuron (Autumn) 2
thiencarbazone (Varro) 2
AxiAl StArpinoxaden (Axial XL)
fluroxypyr (Starane)
AxiAl xl pinoxaden 1
BAlAnce flexx isoxaflutole
BAnvel dicamba 4
BASAgrAn bentazon
BASiS BlenDrimsulfuron (Resolve) 2
thifensulfuron (Harmony) 2
BeAcon primisulfuron
BetAmixdesmedipham (Betenex) 5
phenmedipham 5
Betenex desmedipham
BeyonD imazamox 2
Bicep ii mAgnum(Bicep lite ii magnum)
s-metolachlor (Dual II Magnum)
atrazine (AAtrex)
Bolero thiobencarb 8
BounDAry
s-metolachlor (Dual Magnum)
metribuzin (Metribuzin)
BrAke f2fomesafen (Flexstar) 14
fluridone (Sonar) 12
BreAkfree nxt AtZ(Breakfree nxt lite)
acetochlor (Breakfree NXT)
atrazine (AAtrex)
BroADAxe
s-metolachlor (Dual Magnum)
15
sulfentrazone (Spartan) 14
BroADheADcarfentrazone (Aim)
quinclorac (Facet)
BronAtebromoxynil (Buctril) 6
mcpA (MCPA) 4
Buctril bromoxynil
Bulletalachlor (Micro-Tech) 15
atrazine (AAtrex) 5
Product Active ingredient (Trade Name)
Site of Action
54
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
cADet fluthiacet
cAlliSto mesotrione 27
cAlliSto gtmesotrione (Callisto)
glyphosate (glyphosate)
cAlliSto xtrAmesotrione (Callisto) 27
atrazine (AAtrex) 5
cAnopy chlorimuron (Classic)
metribuzin (Metribuzin)
cAnopy exchlorimuron (Classic) 2
tribenuron (Express) 2
cApArol prometryn
cAprenothiencarbazone (Varro) 2
tembotrione (Laudis) 27
cArnivore
mcpA (MCPA)
clopyralid (Stinger)
bromoxynil (Buctril)
cinch AtZ(cinch AtZ lite)
s-metolachlor (Dual II Magnum)
15
atrazine (AAtrex) 5
clArity dicamba
clASSic chlorimuron 2
cleArmAx imazamox
cleArpAthquinclorac (Facet) 4
imazethapyr (Newpath) 2
clincher cyhalofop
coBrA lactofen 14
colt + SAlvo(trump card)
2,4-D (2,4-D)
fluroxypyr (Starane)
colt + SworDmcpA (MCPA) 4
fluroxypyr (Starane) 4
commAnD clomazone
component of Acuron* bicyclopyrone 27
component of BetAmix phenmedipham
component of huSkie pyrasulfotole 27
component of orion florasulam
component of Quelex* halauxifen 4
component of StAtuS diflufenzopyr
corvuSthiencarbazone (Varro) 2
isoxaflutole (Balance Flexx) 27
cotorAn fluometuron
Product Active ingredient (Trade Name)
Site of Action
55
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
curtAilclopyralid (Stinger)
2,4-D (2,4-D)
curtAil mclopyralid (Stinger) 4
mcpA (MCPA) 4
Define flufenacet
Degree acetochlor 15
Degree xtrAacetochlor (Degree)
atrazine (AAtrex)
Diflexx* dicamba 4
Direx diuron
DiScover ng clodinafop 1
DuAl mAgnum s-metolachlor
enliSt Duo2,4-D (2,4-D) 4
glyphosate (glyphosate) 9
enlite
chlorimuron (Classic)
thifensulfuron (Harmony)
flumioxazin (Valor)
envive
chlorimuron (Classic) 2
thifensulfuron (Harmony) 2
flumioxazin (Valor) 14
envoke trifloxysulfuron
eptAm eptc 8
erADicAne eptc
evereSt flucarbazone 2
expert
s-metolachlor (Dual Magnum)
atrazine (AAtrex)
glyphosate (glyphosate)
expreSS tribenuron 2
extremeimazethapyr (Pursuit)
glyphosate (glyphosate)
fAcet quinclorac 4
fAr-go triallate
fielD mASter
acetochlor (Harness) 15
atrazine (AAtrex) 5
glyphosate (glyphosate) 9
fierceflumioxazin (Valor)
pyroxasulfone (Zidua)
Product Active ingredient (Trade Name)
Site of Action
56
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
fierce xlt
flumioxazin (Valor)
pyroxasulfone (Zidua)
chlorimuron (Classic)
fineSSe chlorsulfuron (Glean) 2
metsulfuron (Ally) 2
fineSSe grASS AnD BroADleAf
chlorsulfuron (Glean)
flucarbazone (Everest)
firStrAte cloransulam 2
flexStAr fomesafen
flexStAr gtfomesafen (Flexstar) 14
glyphosate (glyphosate) 9
foxfirefenoxaprop (Tecoma)
pinoxaden (Axial XL)
fultime nxtacetochlor (TopNotch) 15
atrazine (AAtrex) 5
fuSilADe Dx fluazifop
fuSion fluazifop (Fusilade DX) 1
fenoxaprop (Puma) 1
gAngSterflumioxazin (Valor)
cloransulam (FirstRate)
gleAn chlorsulfuron 2
golDSky
pyroxsulam (PowerFlex HL)
florasulam
fluroxypyr (Starane)
grAmoxone Sl paraquat 22
grAnDStAnD triclopyr
grASp penoxsulam 2
guArDSmAn mAx(g-max lite)
dimethenamid-p (Outlook)
atrazine (AAtrex)
hAlex gt
s-metolachlor (Dual Magnum)
15
mesotrione (Callisto) 27
glyphosate (glyphosate)
hArmony thifensulfuron
hArneSS acetochlor 15
hArneSS xtrAacetochlor (Harness)
atrazine (AAtrex)
hornetclopyralid (Stinger) 4
flumetsulam (Python) 2
Product Active ingredient (Trade Name)
Site of Action
57
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
huSkiepyrasulfotole
bromoxynil (Buctril)
huSkie complete
pyrasulfotole 27
bromoxynil (Buctril) 6
thiencarbazone (Varro) 2
impAct topramezone
inStigAterimsulfuron (Resolve, Matrix) 2
mesotrione (Callisto) 27
intrro alachlor
kArmex diuron 7
kerB pronamide
keyStone nxt(keystone lA nxt)
acetochlor (Surpass NXT) 15
atrazine (AAtrex) 5
lAuDiS tembotrione
leADoffrimsulfuron (Resolve) 2
thifensulfuron (Harmony) 2
lexAr eZ
mesotrione (Callisto)
s-metolachlor (Dual II Magnum)
atrazine (AAtrex)
liBerty glufosinate 10
linex linuron
lonDAx bensulfuron 2
lorox linuron
lumAx eZ
mesotrione (Callisto) 27
s-metolachlor (Dual II Magnum)
15
atrazine (AAtrex) 5
mArkSmAndicamba (Clarity)
atrazine (AAtrex)
mArvelfluthiacet (Cadet) 14
fomesafen (Flexstar) 14
mAtrix rimsulfuron
mAverick sulfosulfuron 2
mcpA mcpA
metriBuZin metribuzin 5
micro-tech alachlor
mSmA mSmA 17
newpAth imazethapyr
Product Active ingredient (Trade Name)
Site of Action
58
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
northStArprimisulfuron (Beacon)
dicamba (Clarity)
nortron ethofumesate 16
oBeyclomazone (Command)
quinclorac (Facet)
olympuS propoxycarbazone 2
optillsaflufenacil (Sharpen)
imazethapyr (Pursuit)
optill pro
saflufenacil (Sharpen) 14
imazethapyr (Pursuit) 2
dimethenamid-p (Outlook) 15
orionflorasulam
mcpA (MCPA)
oSprey mesosulfuron 2
outlook dimethenamid-p
pAnoflexthifensulfuron (Harmony) 2
tribenuron (Express) 2
pArAmount quinclorac
peAk prosulfuron 2
permit halosulfuron
permit pluSthifensulfuron (Harmony) 2
halosulfuron (Permit) 2
phoenix lactofen
plAteAu imazapic 2
poASt sethoxydim
poASt pluS sethoxydim 1
powerflex hl pyroxsulam
pre-pAre flucarbazone 2
prefix
s-metolachlor (Dual Magnum)
fomesafen (Reflex)
preQuelrimsulfuron (Resolve) 2
isoxaflutole (Balance) 27
princep simazine
prioritycarfentrazone (Aim) 14
halosulfuron (Permit) 2
progreSS
desmedipham (Betenex)
phenmedipham
ethofumesate (Nortron)
prowl h2o pendimethalin 3
Product Active ingredient (Trade Name)
Site of Action
59
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
pulSArdicamba (Clarity)
fluroxypyr (Starane)
purSuit imazethapyr 2
python flumetsulam
Quelex*halauxifen 4
florasulam 2
rAptor imazamox
rAvetriasulfuron (Amber) 2
dicamba (Clarity) 4
rAZeflucarbazone (Everest)
fluroxypyr (Starane)
reAlm Qrimsulfuron (Resolve) 2
mesotrione (Callisto) 27
reBelexcyhalofop (Clincher)
penoxsulam (Grasp)
reflex fomesafen 14
regiment bispyribac
reglone diquat 22
reQuire Qrimsulfuron (Resolve)
dicamba (Clarity)
reSolve rimsulfuron 2
reSolve Qrimsulfuron (Resolve)
thifensulfuron (Harmony)
reSource flumiclorac 14
reZultbentazon (Basagran)
sethoxydim (Poast)
riceStAr fenoxaprop 1
rimfire mAxpropoxycarbazone (Olympus)
mesosulfuron (Osprey)
ro-neet cycloate 8
rounDup glyphosate
Scepter imazaquin 2
Select mAx clethodim
SeQuence
s-metolachlor (Dual Magnum)
15
glyphosate (glyphosate) 9
ShArpen saflufenacil
Shotgunatrazine (AAtrex) 5
2,4-D (2,4-D) 4
SierrA flucarbazone
Product Active ingredient (Trade Name)
Site of Action
60
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
SinBAr terbacil
SolSticemesotrione (Callisto) 27
fluthiacet (Cadet) 14
SonAlAn ethalfluralin
SonAr fluridone 12
Sonicsulfentrazone (Spartan)
cloransulam (FirstRate)
SpArtAn sulfentrazone 14
SpArtAn chArgesulfentrazone (Spartan)
carfentrazone (Aim)
Spiritprosulfuron (Peak) 2
primisulfuron (Beacon) 2
StAnZAclopyralid (Stinger)
flumetsulam (Python)
StAple pyrithiobac 2
StArAne fluroxypyr
StArAne flexflorasulam 2
fluroxypyr (Starane) 4
StArAne nxtfluroxypyr (Starane)
bromoxynil (Buctril)
StAtuSdiflufenzopyr 19
dicamba (Clarity) 4
SteADfASt Qnicosulfuron (Accent Q)
rimsulfuron (Resolve)
Stinger clopyralid 4
Stormbentazon (Basagran)
acifluorfen (Ultra Blazer)
StrADA orthosulfamuron 2
SuperwhAm propanil
SupremAcy
fluroxypyr (Starane) 4
thifensulfuron (Harmony) 2
tribenuron (Express) 2
SuprenDprometryn (Caparol)
trifloxysulfuron (Envoke)
SureStArt ii
acetochlor (Surpass) 15
clopyralid (Stinger) 4
flumetsulam (Python) 2
SurpASS nxt acetochlor
Product Active ingredient (Trade Name)
Site of Action
61
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
Surveilflumioxazin (Valor)
cloransulam (FirstRate)
SutAn + butylate 8
Synchrony chlorimuron (Classic)
thifensulfuron (Harmony)
tArgA quizalofop 1
tecomA fenoxaprop
topnotch acetochlor 15
touchDown glyphosate
treflAn trifluralin 3
tripleflex ii
acetochlor (Harness)
clopyralid (Stinger)
flumetsulam (Python)
trivence
chlorimuron (Classic) 2
flumioxazin (Valor) 14
metribuzin (Metribuzin) 5
ultrA BlAZer acifluorfen
upBeet triflusulfuron 2
vAlor flumioxazin
vAlor xltflumioxazin (Valor) 14
chlorimuron (Classic) 2
vAriSito*imazamox (Raptor)
bentazon (Basagran)
vArro thiencarbazone 2
velpAr hexazinone
velpAr AlfAmAxhexazinone (Velpar) 5
diuron (Karmex) 7
verDictsaflufenacil (Sharpen)
dimethenamid-p (Outlook)
wArrAnt acetochlor 15
welD (full Deck)
mcpA (MCPA)
fluroxypyr (Starane)
clopyralid (Stinger)
wiDemAtchclopyralid (Stinger) 4
fluroxypyr (Starane) 4
wolverine
fenoxaprop (Tecoma)
pyrasulfotole
bromoxynil (Buctril)
Product Active ingredient (Trade Name)
Site of Action
62
Herb
icid
e Cla
ssifi
catio
n b
y P
ro
du
ct
yukondicamba (Banvel)
halosulfuron (Permit)
ZemAxmesotrione (Callisto) 27
s-metolachlor (Dual Magnum)
15
ZiDuA pyroxasulfone
Product Active ingredient (Trade Name)
Site of Action
63
This comprehensive herbicide guide was developed with funding from the soy checkoff. The Take Action initiative is supported by the following ag chemical companies and major commodity groups:
*Indicates product is not registered for use at the time of printing.Heap, I. The International Survey of Herbicide Resistant Weeds. Online. Internet, Monday, November 17, 2014. Available www.weedscience.org.Technical editing for this guide was led by Christy Sprague, Ph.D., Michigan State University in partnership with other universities in the soybean-growing regions of the United States.The United Soybean Board and all Take Action partners, including the companies mentioned above, neither recommend nor discourage the implementation of any advice contained herein, and is not liable for the use or misuse of the information provided. ©2014 United Soybean Board.
For more information and links to additional resources, visit www.TakeActionOnWeeds.com.