Abdominal Aortic Aneurysm/Dissection/Injuries

Abdominal Aortic AneurysmMay 2009: Annals of Internal Medicine In The Clinic

Endovascular Repair of Abdominal Aortic Aneurysm N Engl J Med 2008;358:494-501

Aortic InjuriesAcute Aortic Dissection Lancet 2008; 372: 55–66Blunt Aortic Injury N Engl J Med 2008;359:1708-16Commotio Cordis N Engl J Med 2010;362:917-27

Alcohol

Alcohol UseMar 2009: Annals of Internal Medicine In The Clinic

Alcohol-use disorders Lancet 2009; 373: 492–501Alcoholic Hepatitis N Engl J Med 2009;360:2758-69Naltrexone for the Management of Alcohol Dependence N Engl J Med 2008;359:715-21

Allergy/Rhinitis/Sinusitis

Acute RhinitisNov 2007: Annals of Internal Medicine In The Clinic

Acute SinusitisSep 2010: Annals of Internal Medicine In The Clinic

Food Allergy N Engl J Med 2008;359:1252-60Peanut allergy Lancet 2008; 371: 1538–46

AnesthesiaGeneral Anesthesia, Sleep, and Coma N Engl J Med 2010;363:2638-50

ARMDAge-related macular degeneration Lancet 2008; 372: 1835–45Age-Related Macular Degeneration N Engl J Med 2008;358:2606-17Ranibizumab Therapy for Neovascular Age-Related Macular Degeneration N Engl J Med 2010;363:1648-55

Asthma

AsthmaJun 2007: Annals of Internal Medicine In The Clinic

Asthma N Engl J Med 2009;360:1002-14Asthma in Pregnancy N Engl J Med 2009;360:1862-9Emergency Treatment of Asthma N Engl J Med 2010;363:755-64Leukotrienes N Engl J Med 2007;357:1841-54

Alzheimer's DiseaseAlzheimer's Disease N Engl J Med 2010;362:329-44

DementiaApr 2008: Annals of Internal Medicine In The Clinic

Early Alzheimer's DiseaseN Engl J Med 2010;362:2194-201

Back PainAcupuncture for Chronic Low Back Pain N Engl J Med 2010;363:454-61

Low Back PainMay 08: Annals of Internal Medicine In The Clinic

Lumbar Spinal Stenosis N Engl J Med 2008;358:818-25

Barrett's EsophagusBarrett's Esophagus N Engl J Med 2009;361:2548-56Barrett’s oesophagus Lancet 2009; 373:850–61

Behavorial SciencesAssessment of Patients Competence to Consent to Treatment N Engl J Med 2007;357:1834-40Behavioral Management for Anorexia Nervosa N Engl J Med 2009;360:500-6Bipolar Disorder — A Focus on Depression N Engl J Med 2011;364:51-9Borderline personality disorder Lancet 2011; 377: 74–84Eating disorders Lancet 2010; 375: 583–93Evaluation and Management of Enuresis N Engl J Med 2009;360:1429-36Initial Management of Epilepsy N Engl J Med 2008;359:166-76

InsomniaJan 2008: Annals of Internal Medicine In The Clinic

Jet Lag N Engl J Med 2010;362:440-7Obsessive-compulsive disorder Lancet 2009; 374: 491–99Schizophrenia Lancet 2009; 374: 635–45Social anxiety disorder Lancet 2008; 371: 1115–25Suicide Lancet 2009; 373: 1372–81The Delayed-Start Study Design N Engl J Med 361;13

Blood Pressure/SyncopeDecompression illness Lancet 2010; 377: 153–64Dietary Therapy in Hypertension N Engl J Med 2010:362:2102-12

HypertensionDec 2008: Annals of Internal Medicine In The Clinic

Neurogenic Orthostatic Hypotension N Engl J Med 2008;358:615-24Phosphodiesterase Type 5 Inhibitors for Pulmonary Arterial Hypertension N Engl J Med 2009;361:1864-71Renovascular hypertension in children Lancet 2008; 371: 1453–63Use of Diuretics in Patients with Hypertension N Engl J Med 2009;361:2153-64

Breast Cancer

Breast CancerApr 2010: Annals of Internal Medicine In The Clinic

Breast Reconstruction after Surgery for Breast CancerN Engl J Med 2008;359:1590-601

Early breast cancer Lancet 2009; 373: 1463–79Gene-Expression Signatures in Breast Cancer N Engl J Med 2009;360:790-800Radiation Therapy for Early-Stage Breast Cancer after Breast-Conserving Surgery N Engl J Med 2009;360:63-70Susceptibility Pathways in Fanconi's Anemia and Breast Cancer N Engl J Med 2010;362:1909-19Triple Negative Breast Cancer N Engl J Med 2010;363:1938-48

Cardiology GeneralCardiac Development and Implications for Heart Disease N Engl J Med 2010;363:1638-47Cardiac Plasticity N Engl J Med 2008;358:1370-80Chronic Venous Insufficiency and Varicose Veins N Engl J Med 2009;360:2319-27Dilated cardiomyopathy Lancet 2010; 375: 752–62Myocarditis N Engl J Med 2009;360:1526-38Obstructive sleep apnoea and its cardiovascular consequences Lancet 2009; 373: 82–93

Peripheral Arterial DiseaseMar 2007: Annals of Internal Medicine In The Clinic

Preoperative EvaluationJul 2007: Annals of Internal Medicine In The Clinic

Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease N Engl J Med 2010;363:1341-50Should Coronary Calcium Screening Be Used in Cardiovascular Prevention Strategies N Engl J Med 2009;361:990-7Targeted Temperature Management for Comatose Survivors of Cardiac Arrest N Engl J Med 2010;363:1256-64Uric Acid and Cardiovascular Risk N Engl J Med 2008;359:1811-21

Cardiac ArrythmiaArrhythmogenic right ventricular cardiomyopathy Lancet 2009; 373: 1289–1300

Atrial FibrillationDec 2010: Annals of Internal Medicine In The Clinic

Long-QT Syndrome N Engl J Med 2008;358:169-76The QT syndromes long and short Lancet 2008; 372: 750–63

Cancer GeneralChemotherapy-Induced Nausea and Vomiting N Engl J Med 2008;358:2482-94EGFR Antagonists in Cancer Treatment N Engl J Med 2008;358:1160-74Preservation of Fertility in Patients with Cancer N Engl J Med 2009;360:902-11Stereotactic Radiosurgery for the Management of Brain N Engl J Med 2010;362:1119-27

MetastasesTumor Angiogenesis N Engl J Med 2008;358:2039-49

Celiac DiseaseCeliac Disease N Engl J Med 2007;357:1731-43Coeliac disease Lancet 2009; 373: 1480–93

Childhood Behavorial DisordersAutism Lancet 2009; 374: 1627–38Tourette's Syndrome N Engl J Med 2010;363:2332-8

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary DiseaseMar 2008: Annals of Internal Medicine In The Clinic

Immunologic Aspects of Chronic Obstructive Pulmonary Disease N Engl J Med 2009;360:2445-54Infection in the Pathogenesis and Course of Chronic Obstructive Pulmonary Disease N Engl J Med 2008;359:2355-65Outpatient Management of Severe COPD N Engl J Med 2010;362:1407-16Pulmonary Rehabilitation for Management of Chronic Obstructive Pulmonary Disease N Engl J Med 2009;360:1329-35

Colorectal CancerColorectal Cancer Lancet 2010; 375: 1030–47

Colorectal Cancer ScreeningFeb 2008: Annals of Internal Medicine In The Clinic

Molecular Basis of Colorectal Cancer N Engl J Med 2009;361:2449-60Screening for Colorectal Cancer N Engl J Med 2009;361:1179-87

Community InfectionBacterial septic arthritis in adults Lancet 2010; 375: 846–55

Cellulitis and Soft-Tissue InfectionsJan 2009: Annals of Internal Medicine In The Clinic

Vertebral Osteomyelitis N Engl J Med 2010;362:1022-9

Clostridium difficile

Clostridium DifficileOct 2010: Annals of Internal Medicine In The Clinic

Clostridium difficile — More Difficult Than Ever N Engl J Med 2008;359:1932-40

CirrhosisLiver cirrhosis Lancet 2008; 371: 838–51Management of Varices and Variceal Hemorrhage in Cirrhosis N Engl J Med 2010;362:823-32

Renal Failure in Cirrhosis N Engl J Med 2009;361:1279-90

Connective Tissue Disorders

SclerodermaN Engl J Med 2009;360:1989-2003

Critical Care MedicineActivated Protein C for Sepsis N Engl J Med 2009;361:2646-52Glycemic Control in the ICU N Engl J Med 2010;363:2540-6Parenteral Nutrition in the Critically Ill Patient N Engl J Med 2009;361:1088-97

CroupCroup Lancet 2008; 371: 329–39Croup N Engl J Med 2008;358:384-91

CVAIntracerebral haemorrhage Lancet 2009; 373: 1632–44Moyamoya Disease and Moyamoya Syndrome N Engl J Med 2008;359:613-26Stroke Lancet 2008; 371: 1612–23

Transient Ischemic AttackJan 2011: Annals of Internal Medicine In The Clinic

Deep Venous Thrombosis Atheroembolic renal disease Lancet 2010; 375: 1650–60

Deep Venous ThrombosisSep 2008: Annals of Internal Medicine In The Clinic

Venous Thromboembolic Disease and Pregnancy N Engl J Med 2008;359:2025-33

Depression

DepressionMay 2007: Annals of Internal Medicine In The Clinic

Electroconvulsive Therapy for Depression N Engl J Med 2007;357:1939-45Late-Life Depression N Engl J Med 2007;357:2269-76Major Depressive Disorder N Engl J Med 2008;358:55-68Medical Evaluation of Patients Undergoing Electroconvulsive Therapy N Engl J Med 2009;360:1437-44

Dermatology

AcneJul 2008: Annals of Internal Medicine In The Clinic

Atopic Dermatitis N Engl J Med 2008;358:1483-94Current Management of Acute Cutaneous Wounds N Engl J Med 2008;359:1037-46Non-melanoma skin cancer Lancet 2010; 375: 673–85Psoriasis N Engl J Med 2009;361:496-509

Seborrheic Dermatitis N Engl J Med 2009;360:387-96

DiabetesDiabetes in Asia Lancet 2010; 375: 408–18Diabetes in sub-Saharan Africa Lancet 2010; 375: 2254–66

Diabetic KetoacidosisJan 2010: Annals of Internal Medicine In The Clinic

Diabetic retinopathy Lancet 2010; 376: 124–36Glycemic Control in the ICU N Engl J Med 2010;363:2540-6Lipid-induced insulin resistance unravelling the mechanism Lancet 2010; 375: 2267–77Stress hyperglycaemia Lancet 2009; 373: 1798–807

Diabetes Type 1Genetics of Type 1A Diabetes N Engl J Med 2009;360:1646-54Gestational diabetes the need for a common ground Lancet 2009; 373: 1789–97Type 1 diabetes, hyperglycaemia, and the heart Lancet 2008; 371: 1790–99

Diabetes Type 2Genomics, Type 2 Diabetes, and Obesity N Engl J Med 2010;363:2339-50

Type 2 DiabetesMar 2010: Annals of Internal Medicine In The Clinic

Type 2 diabetes pathogenesis and treatment Vol 371 June 28, 2008

DiarrheaBacterial Diarrhea N Engl J Med 2009;361:1560-9Norovirus Gastroenteritis N Engl J Med 2009;361:1776-85

Dyslipidemia

DyslipidemiaAug 2010: Annals of Internal Medicine In The Clinic

Hypertriglyceridemia N Engl J Med 2007;357:1009-17

EmbryologyBiliary atresia Lancet 2009; 374: 1704–13Cleft lip and palate Lancet 2009; 374: 1773–85Effect of In Utero and Early-Life Conditions on Adult Health and Disease N Engl J Med 2008;359:61-73Gestational trophoblastic disease Lancet 2010; 376: 717–29Hypoplastic left heart syndrome Lancet 2009; 374: 551–64Necrotizing Enterocolitis N Engl J Med 2011;364:255-64Prenatal Screening for Aneuploidy N Engl J Med 2009;360:2556-62Tetralogy of Fallot Lancet 2009; 374: 1462–71Velocardiofacial syndrome, DiGeorge syndrome the chromosome 22q11.2 deletion syndromes Lancet 2007; 370: 1443–52

EndocrineHyperparathyroidism Lancet 2009; 374: 145–58Hypoparathyroidism N Engl J Med 2008;359:391-403

HypothyroidismDec 2009: Annals of Internal Medicine In The Clinic

Iodine-deficiency disorders Lancet 2008; 372: 1251–62Precocious Puberty N Engl J Med 2008;358:2366-77Predisposing Factors for Adrenal Insufficiency N Engl J Med 2009;360:2328-39

EndometriosisEndometriosis N Engl J Med 2009;360:268-79Endometriosis N Engl J Med 2010;362:2389-98Gonadotropin-Releasing Hormone Agonists for Endometriosis N Engl J Med 2008;359:1136-42

ENTMeniere’s disease Lancet 2008; 372: 406–14Epistaxis N Engl J Med 2009;360:784-9Vitiligo N Engl J Med 2009;360:160-9

Genetics & CancerCancer Immunology N Engl J Med 2008;358:2704-15Chromosomal Abnormalities in Cancer N Engl J Med 2008;359:722-34DNA Damage, Aging, and Cancer N Engl J Med 2009;361:1475-85Epigenetics in Cancer N Engl J Med 2008;358:1148-59Inherited Susceptibility to Common Cancers N Engl J Med 2008;359:2143-53Molecular Basis of Metastasis N Engl J Med 2008;359:2814-23Oncogenes and Cancer N Engl J Med 2008;358:502-11

Genetics: GeneralAncestry and Disease in the Age of Genomic Medicine N Engl J Med 2010;363:1551-8Cell Death N Engl J Med 2009;361:1570-83Genomewide Association Studies and Assessment of the Risk of Disease N Engl J Med 2010;363:166-76Genomewide Association Studies and Human Disease N Engl J Med 2009;360:1759-68Genomic Medicine — An Updated Primer N Engl J Med 2010;362:2001-11Immunodeficiency and Genetic Defects of Pattern-Recognition Receptors N Engl J Med 2011;364:60-70Nanomedicine N Engl J Med 2010;363:2434-43Telomere Diseases N Engl J Med 2009;361:2353-65

Genetically Inheirted DiseasesAutosomal Dominant Polycystic Kidney Disease N Engl J Med 2008;359:1477-85

Cystic fibrosis Lancet 2009; 373: 1891–904

Genetic Disorders of Renal Phosphate TransportN Engl J Med 2010;362:2399-409

Glucose-6-phosphate dehydrogenase deficiency Lancet 2008; 371: 64–74Hereditary spherocytosis Lancet 2008; 372: 1411–26Neurofibromatosis type 2 Lancet 2009; 373: 1974–86New Therapeutic Approaches to Mendelian Disorders N Engl J Med 2010;363:852-63Phenylketonuria Lancet 2010; 376: 1417–27Tuberous sclerosis Lancet 2008; 372: 657–68Williams–Beuren Syndrome N Engl J Med 2010;362:239-52

GERD

Gastroesophageal Reflux DiseaseAug 2008: Annals of Internal Medicine In The Clinic

Gastroesophageal Reflux Disease N Engl J Med 2008;359:1700-7

GenitourinaryBladder cancer Lancet 2009; 374: 239–49Genital herpes Lancet 2007; 370: 2127–37Idiopathic Urgency Urinary Incontinence N Engl J Med 2010;363:1156-62Urinary Stress Incontinence in Women N Engl J Med 2008;358:1029-36

Gout

GoutFeb 2010: Annals of Internal Medicine In The Clinic

Gout Lancet 2010; 375: 318–28

Grave's Disease

Graves' DiseaseN Engl J Med 2008;358:2594-605

Graves' OphthalmopathyN Engl J Med 2009;360:994-1001

Graves' Ophthalmopathy N Engl J Med 2010;362:726-38

GynecologyFunctional Hypothalamic Amenorrhea N Engl J Med 2010;363:365-71Hair Loss in Women N Engl J Med 2007;357:1620-30Hormonal Contraception in Women of Older Reproductive Age N Engl J Med 2008;358:1262-70Metformin for the Treatment of the Polycystic Ovary Syndrome N Engl J Med 2008;358:47-54Uterine Fibroid Embolization N Engl J Med 2009;361:690-7

Vaginitis and CervicitisSep 2009: Annals of Internal Medicine In The Clinic

HepatobillaryAcute Calculous Cholecystitis N Engl J Med 2008;358:2804-11Acute liver failure Lancet 2010; 376: 190–201Alpha1-Antitrypsin Deficiency N Engl J Med 2009;360:2749-57Haemochromatosis Lancet 2007; 370: 1855–60Hepatopulmonary Syndrome — A Liver-Induced Lung Vascular Disorder N Engl J Med 2008;358:2378-87Phototherapy for Neonatal Jaundice N Engl J Med 2008;358:920-8Ursodeoxycholic Acid for the Treatment of Primary Biliary Cirrhosis N Engl J Med 2007;357:1524-9

Hearing LossCochlear Implants for Children with Severe-to-Profound Hearing Loss N Engl J Med 2007;357:2380-7Idiopathic Sudden Sensorineural Hearing Loss N Engl J Med 2008;359:833-40Profound Deafness in Childhood N Engl J Med 2010;363:1438-50Sudden sensorineural hearing loss Lancet 2010; 375: 1203–11

Heart FailureBiomarkers in Heart Failure N Engl J Med 2008;358:2148-59

Heart FailureJune 2010: Annals of Internal Medicine In The Clinic

Heart failure Lancet 2009; 373: 941–55Systolic Heart Failure N Engl J Med 2010;362:228-38

HematologyAtypical Hemolytic–Uremic Syndrome N Engl J Med 2009;361:1676-87Hereditary Angioedema N Engl J Med 2008;359:1027-36Myelodysplastic Syndromes N Engl J Med 2009;361:1872-85Porphyrias Lancet 2010; 375: 924–37

Hemorrhagic FeverDengue Lancet 2007; 370: 1644–52Ebola haemorrhagic fever Lancet 11/16/2010Omsk haemorrhagic fever Lancet 2010; 376: 2104–13Pathogenic flaviviruses Lancet 2008; 371: 500–09

Hepatitis BHepatitis B virus infection Lancet 2009; 373: 582–92

Hepatitis B Virus InfectionN Engl J Med 2008;359:1486-500

Hepatitis C

Acute hepatitis C Lancet 2008; 372: 321–32

Hepatitis CJun 2008: Annals of Internal Medicine In The Clinic

HIVAntiretroviral therapy and management of HIV infection Lancet 2010; 376: 49–62Postexposure Prophylaxis for HIV Infection N Engl J Med 2009;361:1768-75

The Challenge of HIV-1 Subtype DiversityN Engl J Med 2008;358:1590-602

HPV & Cervical CancerHPV Vaccination for the Prevention of Cervical Intraepithelial Neoplasia N Engl J Med 2009;361:271-8Human papillomavirus and cervical cancer Lancet 2007; 370: 890–907

Inflammatory Bowel Disease/Diverticular DiseaseDiverticulitis N Engl J Med 2007;357:2057-66Inflammatory Bowel Disease N Engl J Med 2009;361:2066-78

Intestinal TransplantationN Engl J Med 2009;361:998-1008

InfluenzaClinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection N Engl J Med 2010;362:1708-19Historical Perspective — Emergence of Influenza A (H1N1) Viruses N Engl J Med 2009;361:279-85Human infection with highly pathogenic H5N1 influenza virus Lancet 2007; 371: 1464–75

InfluenzaNov 2009: Annals of Internal Medicine In The Clinic

Influenza Vaccines for the Future N Engl J Med 2010;363:2036-44Prevention and Treatment of Seasonal Influenza N Engl J Med 2008;359:2579-85Update on Avian Influenza A (H5N1) Virus Infection in Humans N Engl J Med 2008;358:261-73

Irritable Bowel Disease

Irritable Bowel SyndromeJuly 2007: Annals of Internal Medicine In The Clinic

Irritable Bowel Syndrome N Engl J Med 2008;358:1692-9

ImmunologyCommon variable immunodeficiency a new look at an old disease Lancet 2008; 372: 489–502Graft-versus-host disease Lancet 2009; 373: 1550–61Infection in Solid-Organ Transplant Recipients N Engl J Med 2007;357:2601-14

Interleukin-17 and Type 17 Helper T Cells N Engl J Med 2009;361:888-98Sublingual Immunotherapy N Engl J Med 2008;358:2259-64

LeukemiaAcute lymphoblastic leukaemia Lancet 2008; 371: 1030–43Chronic lymphocytic leukaemia Lancet 2008; 371: 1017–29

LymphomaAggressive Lymphomas N Engl J Med 2010;362:1417-29Early-Stage Hodgkin's Lymphoma N Engl J Med 2010;363:653-62Monoclonal Antibody Therapy for B-Cell Non-Hodgkin's Lymphoma N Engl J Med 2008;359:613-26Mycosis fungoides and Sézary syndrome Lancet 2008; 371: 945–57

MalariaArtesunate for the Treatment of Severe Falciparum Malaria N Engl J Med 2008;358:1829-36Malaria in children Lancet 2010; 375: 1468–81Malaria Prevention in Short-Term Travelers N Engl J Med 2008;359:603-12

Menopause & PMS

MenopauseApr 2009: Annals of Internal Medicine In The Clinic

Menopause Lancet 2008; 371: 760–70Premenstrual syndrome Lancet 2008; 371: 1200–10

MIAcute myocardial infarction Lancet 2008; 372: 570–84Implantable Cardioverter–Defibrillators after Myocardial Infarction N Engl J Med 2008;359:2245-53Time to Treatment in Primary Percutaneous Coronary Intervention N Engl J Med 2007;357:1631-8

MicrobiologyA Critical Appraisal of Chronic Lyme Disease N Engl J Med 2007;357:1422-30Advances in the Development of Vaccines against Neisseria meningitidis N Engl J Med 2010;362:1511-20Aspergillosis N Engl J Med 2009;360:1870-84Chagas disease Lancet 2010; 375: 1388–402Community-associated meticillin-resistant Staphylococcus aureus Lancet 2010; 375: 1557–68Control of Neglected Tropical Diseases N Engl J Med 2007;357:1018-27Fungal Nail Disease N Engl J Med 2009;360:2108-16Human African trypanosomiasis Lancet 2010; 375: 148–59Infectious Mononucleosis N Engl J Med 2010;362:1993-

2000Lymphatic filariasis and onchocerciasis Lancet 2010; 376: 1175–85Maternal and neonatal tetanus Lancet 2007; 370: 1947–59Permethrin and Ivermectin for Scabies N Engl J Med 2010;362:717-25Tick-borne encephalitis Lancet 2008; 371: 1861–71

Migraine

MigraineNov 2007: Annals of Internal Medicine In The Clinic

Recent developments in migraineThe Lancet Vol 372 October 18, 2008

Triptan Therapy in Migraine N Engl J Med 2010;363:63-70

Mitral ValveMitral Regurgitation Due to Degenerative Mitral-Valve Disease N Engl J Med 2010;363:156-65Mitral stenosis Lancet 2009; 374: 1271–83Mitral-Valve Repair for Mitral-Valve Prolapse N Engl J Med 2009;361:2261-9

Multiple MyelomaAutologous Hematopoietic Stem-Cell Transplantation for Multiple Myeloma N Engl J Med 2009;360:2645-54Multiple myeloma Lancet 2009; 374: 324–39

Multiple SclerosisMultiple sclerosis Lancet 2008; 372: 1502–17

MuscularJuvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood Lancet 2008; 371: 2201–12Polymyalgia rheumatica and giant-cell arteritis Lancet 2008; 372: 234–45

NephrolithiasisCalcium Kidney Stones N Engl J Med 2010;363:954-63

NephrolithiasisAug 2009: Annals of Internal Medicine In The Clinic

NeurologyHead and neck cancer Lancet 2008; 371: 1695–709Malignant Gliomas in Adults N Engl J Med 2008;359:492-507Prolactinomas N Engl J Med 2010;362:1219-26Recent Advances in Head and Neck Cancer N Engl J Med 2008;359:1143-54Recent Advances in Neuroblastoma N Engl J Med 2010;362:2202-11Transverse Myelitis N Engl J Med 2010;363:564-72

NosocomialAcinetobacter Infection N Engl J Med 2008;358:1271-81Hospital-Acquired Infections Due to Gram-Negative Bacteria N Engl J Med 2010;362:1804-13

ObesityChildhood obesity Lancet 2010; 375: 1737–48Nonsurgical Management of Obesity in Adults N Engl J Med 2008;358:1941-50

ObesityOct 2008: Annals of Internal Medicine In The Clinic

ObstetricsEctopic Pregnancy N Engl J Med 2009;361:379-87Epidural Analgesia for Labor and Delivery N Engl J Med 2010;362:1503-10Maternal and Neonatal Herpes Simplex Virus Infections N Engl J Med 2009;361:1376-85Molar Pregnancy N Engl J Med 2009;360:1639-45Nausea and Vomiting in Pregnancy N Engl J Med 2010;363:1544-50Pre-eclampsia Lancet 2010; 376: 631–44Recurrent Miscarriage N Engl J Med 2010;363:1740-7

OpthamologyPrimary Open-Angle Glaucoma N Engl J Med 2009;360:1113-24Primary Retinal Detachment N Engl J Med 2008;359:2346-54Retinal-Vein Occlusion N Engl J Med 2010;363:2135-44Trachoma Lancet 2007; 371: 1945–54

OsteoarthritisMinimally Invasive Total Knee Arthroplasty for Osteoarthritis N Engl J Med 2009;360:1749-58

OsteoarthritisAug 2007: Annals of Internal Medicine In The Clinic

Osteoarthritis of the Hip N Engl J Med 2007;357:1413-21

OsteoporosisBisphosphonates for Osteoporosis N Engl J Med 2010;363:2027-35Osteoporosis in Men N Engl J Med 2008;358:1474-82

Ovarian CancerOvarian cancer Lancet 2009; 374: 1371–82Screening for Ovarian Cancer N Engl J Med 2009;361:170-7.

Pancreas

Acute PancreatitisNov 2010: Annals of Internal Medicine In The Clinic

Acute Pancreatitis Lancet 2008; 371: 143–52Pancreatic Cancer N Engl J Med 2010;362:1605-17

Parkinson’s DiseaseLevodopa for the Treatment of Parkinson's Disease N Engl J Med 2008;359:2468-76Parkinson’s disease Lancet 2009; 373: 2055–66

Peptic Ulcer / CancerGastric cancer Lancet 2009; 374: 477–90

Helicobacter pylori InfectionN Engl J Med 2010;362:1597-604

Management of Acute Bleeding from a Peptic Ulcer N Engl J Med 2008;359:928-37Peptic ulcer disease Lancet 2009; 374: 1449–61

Pneumonia

Community-Acquired PneumoniaOct 2009: Annals of Internal Medicine In The Clinic

Pathogenesis, treatment, and prevention of pneumococcal pneumonia Lancet 2009; 374: 1543–56

PretermChronic Lung Disease after Premature Birth N Engl J Med 2007;357:1946-55Management and Outcomes of Very Low Birth Weight N Engl J Med 2008;358:1700-11The Enigma of Spontaneous Preterm Birth N Engl J Med 2010;362:529-35The Sudden Infant Death Syndrome N Engl J Med 2009;361:795-805

Primary Ovarian InsufficiencyPrimary ovarian insufficiency Lancet 2010; 376: 911–21Primary Ovarian Insufficiency N Engl J Med 2009;360:606-14

Prostate/Male ReproductiveErectile Dysfunction N Engl J Med 2007;357:2472-81Gynecomastia N Engl J Med 2007;357:1229-37

Localized Prostate CancerN Engl J Med 2007;357:2696-705

Prostate cancer Lancet 2008; 371: 1710–21

Pulmonary EmbolismAcute Pulmonary Embolism N Engl J Med 2008;358:1037-52Acute Pulmonary Embolism N Engl J Med 2008;359:2804-13Acute Pulmonary Embolism N Engl J Med 2010;363:266-74New diagnostic strategies for pulmonary embolism Lancet Vol 371 April 19, 2008Pulmonary embolism in pregnancy Lancet 2010; 375: 500–12

RadiologyComputed Tomography — An Increasing Source of Radiation Exposure N Engl J Med 2007;357:2277-84

Renal

Acute kidney injuryThe Lancet Vol 372 November 29, 2008

Chronic Kidney DiseaseFeb 2009: Annals of Internal Medicine In The Clinic

Hemodialysis N Engl J Med 2010;363:1833-45Oral Phosphate Binders in Patients with Kidney Failure N Engl J Med 2010;362:1312-24Rejection of the Kidney Allograft N Engl J Med 2010;363:1451-62Renal cell carcinoma Lancet 2009; 373: 1119–32Renal-Artery Stenosis N Engl J Med 2009;361:1972-8Rhabdomyolysis and Acute Kidney Injury N Engl J Med 2009;361:62-72Small Renal Mass N Engl J Med 2010;362:624-34Stage IV Chronic Kidney Disease N Engl J Med 2010;362:56-65Uremia N Engl J Med 2007;357:1316-25

RespiratoryAcute Lower Respiratory Tract Infection N Engl J Med 2008;358:716-27Airway Mucus Function and Dysfunction N Engl J Med 2010;363:2233-47Low-Tidal-Volume Ventilation in the Acute Respiratory Distress Syndrome N Engl J Med 2007;357:1113-20Lung Cancer N Engl J Med 2008;359:1367-80Sarcoidosis N Engl J Med 2007;357:2153-65

Rheumatoid Arthritis

Rheumatoid ArthritisJul 2010: Annals of Internal Medicine In The Clinic

Rheumatoid arthritis Lancet 2009; 373: 659–72

Skeletal PathologyAdolescent idiopathic scoliosis Lancet 2008; 371: 1527–37Anterior Cruciate Ligament Tear N Engl J Med 2008;359:2135-42Infection Associated with Prosthetic Joints N Engl J Med 2009;361:787-94Pathogenesis and management of Paget’s disease of bone Lancet 2008; 372: 155–63Rotator-Cuff Failure N Engl J Med 2008;358:2138-47Spinal muscular atrophy Lancet 2008; 371: 2120–33

Temporomandibular DisordersN Engl J Med 2008;359:2693-705

SLEAntiphospholipid syndrome Lancet 2010; 376: 1498–1509

Systemic Lupus Erythematosus N Engl J Med 2008;358:929-39

Sickle Cell DiseaseHydroxyurea for the Treatment of Sickle Cell Anemia N Engl J Med 2008;358:1362-9Iron-Chelating Therapy for Transfusional Iron Overload N Engl J Med 2011;364:146-56Pulmonary Complications of Sickle Cell Disease N Engl J Med 2008;359:2254-65Sickle-cell disease Lancet 2010; 376: 2018–31

Smoking

Nicotine AddictionN Engl J Med 2010;362:2295-303

Smoking CessationFeb 2007 Annals of Internal Medicine In The Clinic

Tobacco addiction Lancet 2008; 371: 2027–38Varenicline for Tobacco Dependence N Engl J Med 2008;359:2018-24

TuberculosisMDR Tuberculosis — Critical Steps for Prevention and Control N Engl J Med 2010;363:1050-8

TuberculosisJun 2009: Annals of Internal Medicine In The Clinic

Tuberculosis Lancet 2007; 370: 2030–43

ThrombogenesisPlatelet Activation and Atherothrombosis N Engl J Med 2007;357:2482-94Platelets, Petechiae, and Preservation of the Vascular Wall N Engl J Med 2008;359:1261-70Mechanisms of Thrombus Formation N Engl J Med 2008;359:938-49

ToxinsAcetylcysteine for Acetaminophen Poisoning N Engl J Med 2008;359:285-92Carbon Monoxide Poisoning N Engl J Med 2009;360:1217-25Fomepizole for Ethylene Glycol and Methanol Poisoning N Engl J Med 2009;360:2216-23Snake bite Lancet 2010; 375: 77–88

Trauma/BurnsBlast injuries Lancet 2009; 374: 405–15Excision and Skin Grafting of Thermal Burns N Engl J Med 2009;360:893-901

VitaminsVitamin D Insufficiency N Engl J Med 2011;364:248-54