HIGH YIELD TOPICS OF MRCP-1 (PASSMEDICINE)

CARDIOLOGY Hypertension (33) Atrial Fibrillation (24) Infective Endocarditis (22) ECG (18) Hypertrophic Obstructive Cardiomyopathy (13) Long QT Syndrome (13) Heart Sounds (12) Pulmonary Arterial Hypertension (12) Acute Coronary Syndrome (11) Pulmonary Embolism (10) Myocardial Infarction (10) Heart Failure (9) Jugular Venous Pulse (9) Statins (9) Warfarin (9) Aortic Stenosis (7) Thiazide Diuretics (7) Acute Pericarditis (6) B-Type Natriuretic Peptide (6) Aortic Dissection (6) Angina Pectoris (5) Tricuspid Regurgitation (5) Supraventricular Tachycardia (5) Wolff-Parkinson White (5) Ventricular Tachycardia (5) Peri-Arrest Rhythms (5) Prosthetic Heart Valves (5) DVLA: Cardiovascular Disorders (5) Dilated Cardiomyopathy (4) Eisenmenger’s Syndrome (4) ACE Inhibitors (4) Clopidogrel (4) Loop Diuretics (4) Chest Pain (4) Broad Complex Tachycardia (3) Cardiac Enzymes and Protein Markers (3) Cardiac Imaging: Non-Invasive Techniques (3) Exercise (3) Pulses (3)

Amiodarone (3) Pre-Eclampsia (3) Eclampsia (3) Takayasu’s Arteritis (3) Brugada Syndrome (3) Percutaneous Coronary Intervention (3) Cholesterol Embolisation (3) Adult Advanced Life Support (3) Torsades de Pointes (3) Adenosine (3) Arrhythmogenic Right Ventricular Cardiomyopathy (2) Dipyridamole (2) Coronary Circulation (2) Atrial Myxoma (2) Hypercalcaemia: Features (2) Coarctation of the Aorta (2) Ventricular Septal Defect (2) Atrial Flutter (2) Complete Heart Block (2) Aortic Regurgitation Malignant Hypertension (1) Isolated Systolic Hypertension (1) Blood pressure measurement (1) Centrally Acting Hypertensives (1) Diabetes Mellitus: Hypertension Management (1) Pacemakers: Temporary (1) Chronic Heart Failure: Diagnosis (1)

RESPIRATORY COPD (23) Asthma (18) Lung Cancer (16) Sarcoidosis (12) Pneumothorax (9) Alpha-1 Antitrypsin Deficiency (7) Lung Fibrosis (6) Transfer Factor (6) Smoking Cessation (5) Extrinsic Allergic Alveolitis (5) Bronchiectasis (5) Non-Invasive Ventilation (5) Pneumonia (5) Chest X-ray (4) Pleural Effusion (4) Altitude Related Disorders (4) Obstructive Sleep Apnoea (4) Respiratory Alkalosis & Acidosis (4) Oxygen Dissociation Curve (4) Psittacosis (3) Allergic Bronchopulmonary Aspergillosis (3) Silicosis (3) Respiratory Physiology: Lung Volumes (3) Oxygen Therapy (3) Idiopathic Pulmonary Fibrosis (3) Eosinophilic Granulomatosis with Polyangitis (3) Kartagener’s Syndrome (2) Pulmonary Function Tests (2) Pulmonary Hypertension (2) Klebsiella (2) Leukotriene Receptor Antagonists (2) Acute Respiratory Distress Syndrome (2) Rheumatoid Arthritis (2) Asbestos & Mesothelioma (2)

GASTROENTEROLOGY Colorectal Cancer (11) Acute Pancreatitis (11) Coeliac Disease (10) Clostridium Difficile (9) Haemochromatosis (9) Helicobacter Pylori (8) Ulcerative Colitis (8) Crohn’s Disease (8) Hepatitis B Serology (8) Variceal Haemorrhage (6) Irritable Bowel Syndrome (6) Drug-Induced Liver Disease (6) Spontaneous Bacterial Peritonitis (6) Non-Alcoholic Fatty Liver Disease (5) Oesophageal Cancer (5) Hepatocellular Carcinoma (5) Autoimmune Hepatitis (4) Wilson’s Disease (4) Primary Biliary Cholangitis (4) Refeeding Syndrome (4) Peutz-Jeghers Syndrome (4) Angiodysplasia (4) Ischaemia to the Lower Gastrointestinal Tract (4) Inflammatory Bowel Disease: Key Differences (3) Carcinoid Tumours (3) Dysphagia (3) Achalasia (3) Anal Fissure (3) Obesity: Bariatric Surgery (3) Gilbert’s Syndrome (3) Hepatorenal Syndrome (3) Whipple’s Disease (3) Small Bowel Bacterial Overgrowth Syndrome (3) Scoring Systems for Liver Cirrhosis (3) Acute Upper & Upper Gastrointestinal Bleeding (3) Barrett’s Oesophagus (3) Pancreatic Cancer (3) Aminosalicylate Drugs (2) Pernicious Anaemia (2) Ischaemic Hepatitis (2) Primary Sclerosing Cholangitis (2) Acute Liver Failure (2) Zollinger-Ellison Syndrome (2) Liver Cirrhosis (2) Chronic Pancreatitis (2)

HIV: Biliary and Pancreatic Disease (2) Malabsorption (2) Pregnancy: Jaundice (2) Budd-Chiari Syndrome (2) Alcoholic Liver Disease (2) Gastrointestinal Physiology: Enzymes (2) Gastric Cancer (2) Pyogenic Liver Abscess (2) Proton Pump Inhibitors (1)

INFECTIOUS DISEASES HIV (33) Meningitis (14) Malaria (13) Syphilis (11) Tuberculosis (8) Trypanosomiasis (8) Classification of Bacteria (7) Vaccinations (7) Gastroenteritis (7) Animal and Human Bites (7) Post-Exposure Prophylaxis (7) Amoebiasis & Giardiasis (6) STI: Ulcers (6) Lyme Disease (6) Chlamydia (6) Hepatitis C (6) Schistosomiasis (6) Gonorrhoea (5) Aspergilloma (5) Urinary Tract Infection in Adults (5) Infectious Mononucleosis (5) Leptospirosis (5) Chickenpox Exposure in Pregnancy (5) Pneumonia: Causes (5) Hepatitis B (4) Leishmaniasis (4) Toxoplasmosis (4) Tetanus (4) Legionella (4) Genital Warts (4) Leprosy (3) Splenectomy (3) Botulism (3) Nematodes (3) Enteric Fever (Typhoid/Paratyphoid) Mycoplasma Pneumoniae (3) Epstein-Barr Virus: Associated Conditions (3) Streptococci (3) Anthrax (3) Bacterial Vaginosis (3) Rabies (3) Antibiotic Guidelines (1) Antifungal Agents (2) Antiviral Agents (4)

Dengue Fever (2) Chikungunya (2) Brucellosis (2) Listeria (2) Strongyloides Stercoralis (2) H1N1 (2) Zika Virus (2) Trimethoprim (2) Staphylococcal Toxic Shock Syndrome (2) Cellulitis (2) Identifying Gram Positive Bacteria (2) MRSA (2) Diphtheria (2) Cat Scratch Disease (2) Necrotising Fasciitis (2) Parvovirus B19 (2)

NEPHROLOGY Chronic Kidney Disease (13) Diabetes Insipidus (13) ADPKD (11) Renal Stones (11) Acute Kidney Injury (10) Renal Transplant (6) Benign Prostatic Hyperplasia (5) Minimal Change Disease (5) IgA Nephropathy (5) Glomerulonephritides (5) Spironolactone (4) Goodpasture’s Syndrome (4) Nephrotic Syndrome (4) Systemic Lupus Erythematosus: Renal Complications (4) Haemolytic Uraemic Syndrome (4) Prostate Cancer (4) Henoch-Schonlein Purpura (3) Renal Cell Cancer (3) Rhabdomyolysis (3) Fibromuscular Dysplasia (3) Renal Vascular Disease (3) Membranous Glomerulonephritis (3) Renal Cell Cancer (3) Amyloidosis (3) Metabolic Acidosis (3) Haematuria (2) Focal Segmental Glomerulosclerosis (2) Bladder Cancer: Risk Factors (2) Plasma Exchange (2) Fanconi Syndrome (2) Membranoproliferative Glomerulonephritis (2) Cystinuria (2) Fluid Therapy (2) Arteriovenous Fistulas (2) Erythropoietin (2) Alport’s Syndrome (2) Peritoneal Dialysis (2) Rapidly Progressive Glomerulonephritis (2) Nephrotoxicity due to Contrast Media (2)

HAEMATOLOGY & ONCOLOGY Cytotoxic Agents (17) Tumour Markers (9) Blood Products & Transfusion (10) Chronic Lymphocytic Leukaemia (9) Hereditary Angioedema (7) Waldenstrom’s Macroglobulinaemia (7) Sickle Cell (7) Hodgkin’s Lymphoma (6) Thrombotic Thrombocytopaenic Purpura (6) Haematological Malignancies (6) G6PD Deficiency (6) Primary Immunodeficiency (5) ITP (5) Myeloma (5) Allergy Tests (5) Von Willebrand’s Disease (5) Superior Vena Cava Obstruction (5) Burkitt’s Lymphoma (5) Hereditary Spherocytosis (5) Autoimmune Haemolytic Anaemia (5) Polycythaemia (5) Acute Intermittent Porphyria (4) Acute Myeloid Leukaemia (4) Chronic Myeloid Leukaemia (4) Lead Poisoning (4) Wiskott-Aldrich Syndrome (3) Neutropenia & Neutropenic Sepsis (3) Vitamin B12 Deficiency (3) Factor V Leiden (3) Thrombocytosis (3) Leucocyte Alkaline Phosphatase (3) Anti-Oestrogen Drugs (3) Neoplastic Spinal Cord Compression (3) Haemolytic Anaemia (3) Cryoglobulinaemia (3) Methaemoglobulinaemia (3) Anaphylaxis (3) Paroxysmal Nocturnal Haemoglobinuria (3) Tumour Lysis Syndrome (3) Anti-Oestrogen Drugs (3) Antithrombin III Deficiency (2) Acute Lymphoblastic Leukaemia (2) Chemotherapy Side-Effects: Nausea and Vomiting Deep Vein Thrombosis (2)

Antiphospholipid Syndrome: Pregnancy Sideroblastic Anaemia (2) Haemophilia (2) Leukemoid Reaction (2) Myelofibrosis (2) Carcinogens (2) Beta-Thalassaemia Trait (2) Hyposplenism (2) Venous Thromboembolism (2) Blood Films (2) Thymoma (2)

NEUROLOGY Parkinson’s Disease (16) Stroke (16) Epilepsy & Status Epilepticus (15) Migraine (13) Brain Lesions (13) Degenerative Cervical Myelopathy (12) Guillain-Barre Syndrome (11) Multiple Sclerosis (10) Visual Field Defects (9) Motor Neuron Disease (7) Phenytoin (7) Myasthenia Gravis (7) Benign Paroxysmal Positional Vertigo & Vertigo (6) Neuroleptic Malignant Syndrome (6) 5-HT3 Antagonists (5) Cluster Headache (5) Lambert-Eaton Syndrome (5) Myotonic Dystrophy (5) Paraneoplastic Syndromes Affecting Nervous System (5) Essential Tremor (5) Tuberous Sclerosis (5) Subarachnoid Haemorrhage (5) Wernicke’s Encephalopathy (4) Idiopathic Intracranial Hypertension (4) Peripheral Neuropathy (4) Neurofibromatosis (4) Restless Legs Syndrome (4) Bell’s Palsy (4) Normal Pressure Hydrocephalus (4) Subacute Combined Degeneration of the Spinal Cord (4) Neuropathic Pain (4) Spastic Paraparesis (3) Third Nerve Palsy (3) Von Hippel-Lindau Syndrome (3) Facial Nerve Palsy (3) Chorea (3) Meniere’s Disease (3) Sodium Valproate (3) Head Injury (3) Post-Lumbar Puncture Headache (3) Herpes Simplex Encephalitis (3) Friedrich’s Ataxia (3) Common Peroneal Nerve Lesion (3) DVLA: Neurological Disorders (3) Creutzfeldt-Jakob Disease (3)

Absence Seizures (2) Transient Ischaemic Attack (2) Transient Global Amnesia (2) Cataplexy (2) Syringomyelia (2) Ataxia Telangiectasia (2) Brown-Sequard Syndrome (2) HSMN (2) Brain Abscess (2) Progressive Supranuclear Palsy (2) Cerebrospinal Fluid (2) Subdural Haemorrhage (2) Rinne’s and Weber’s Test (2) Anti-NMDA Receptor Encephalitis (2) Gingival Hyperplasia (2) Hemiballism (2) Triptans (2) Intracranial Haemorrhage (2) Cerebellar Syndrome (2) Intracranial Venous Thrombosis (2)

OPHTHALMOLOGY Sudden Loss of Vision (7) Age-Related Macular Degeneration (6) Horner’s Syndrome (5) Primary Open-Angle Glaucoma (4) Acute Angle Closure Glaucoma (4) Relative Afferent Pupillary Defect (4) Herpes Zoster Ophthalmicus (3) Retinitis Pigmentosa (3) Rheumatoid Arthritis: Ocular Manifestations (3) Diabetic Retinopathy (2) Holmes-Adie Pupil (2) Angioid Retinal Steaks (2) Blepharitis (2)

PSYCHIATRY Antipsychotics & Atypical Antipsychotics (10) Personality Disorders (9) Selective Serotonin Reuptake Inhibitors and Their Side Effects (9) Charles-Bonnet Syndrome (7) Unexplained Symptoms (7) Schizophrenia (5) Post-Traumatic Stress Disorder (5) Post-Partum Mental Health Problems (3) Hypomania vs. Mania (3) Cotard Syndrome (3) Tricyclic Antidepressants (3) Depression (3) Bulimia Nervosa and Anorexia Nervosa (3) Alcohol Withdrawal (2) Korsakoff’s Syndrome (2) Lithium (2) Benzodiazepines (2) Suicide: Risk Factors (2)

GERIATRIC MEDICINE Alzheimer’s Disease (11) Acute Confusional State (5) Lewy Body Dementia (4) Dementia (3) Vascular Dementia (2) Delirium vs. Dementia (2) Pressure Ulcers (2)

PALLIATIVE MEDICINE & END OF LIFE CARE Palliative Care Prescribing: Pain (23)

ENDOCRINOLOGY Diabetes Mellitus (40) Primary Hyperaldosteronism (11) SGLT-2 Inhibitors (9) Addison’s Disease (9) Acromegaly (9) Cushing’s Syndrome (8) Graves’ Disease (7) Thyroid Eye Disease (5) Sulfonylurea (5) Corticosteroids (5) Hypercalcaemia (5) Hypothyroidism (5) Primary Hyperparathyroidism (5) Multiple Endocrine Neoplasia (4) Polycystic Ovarian Syndrome (4) Gynaecomastia (4) Urinary Incontinence (4) Hypoglycaemia (4) Thiazolidinediones (4) Prolactin and Galactorrhoea (3) Thyroid Cancer (3) Prediabetes and Impaired Glucose Regulation (3) Insulinoma (3) Pregnancy: Thyroid Problems (3) Pregnancy: Diabetes Mellitus (3) Klinefelter’s Syndrome (3) Glycosylated Haemoglobin (3) Subacute (De Quervain’s) Thyroiditis (3) Toxic Multinodular Goitre (2) Menstrual Cycle (2) Subclinical Hyperthyroidism (2) Phaeochromocytoma (2) Metabolic Syndrome (2) Thyroid Storm (2) Kallmann’s Syndrome (2) Hashimoto’s Thyroiditis (2) Pendred’s Syndrome (2) Sick Euthyroid Syndrome (2) Gitelman’s Syndrome (2) DVLA: Diabetes Mellitus

RHEUMATOLOGY Osteoporosis (14) Rheumatoid Arthritis (13) Gout (11) Ankylosing Spondylitis (10) Systemic Lupus Erythematosus (9) Marfan’s Syndrome (8) Bisphosphonates (6) Osteomalacia (6) Dermatomyositis (6) Antiphospholipid Syndrome (5) Reactive Arthritis (5) Temporal Arteritis (5) Paget’s Disease of the Bone (5) Septic Arthritis (5) Pseudogout (4) Raynaud’s (4) Lower Back Pain (4) Systemic Sclerosis (4) ANCA (4) Psoriatic Arthropathy (4) Osteoarthritis (4) Azathioprine (3) Elbow Pain (3) Lateral Epicondylitis (3) Osteomyelitis (3) Sjogren’s syndrome (3) Adhesive Capsulitis (3) Carpal Tunnel Syndrome (3) Polyarteritis Nodosa (3) Avascular Necrosis of the Hip (3) McArdle’s Disease (2) Sulfasalazine (2) Behcet’s Syndrome (2) Still’s Disease in Adults (2) Drug-Induced Lupus (2) Osteopetrosis (2) Pseudoxanthoma Elasticum (2) Methotrexate (2) Discoid Lupus Erythematosus (2) Familial Mediterranean Fever (2) Tumour Necrosis Factor (2) Chronic Fatigue Syndrome (2) Mixed Connective Tissue Disease (2) Denosumab (2)

DERMATOLOGY Acne Rosacea (9) Psoriasis (7) Erythema Nodosum (6) Seborrheic Dermatitis in Adults (6) Eczema (6) Scabies (5) Lichen Planus (5) Pellagra (5) Acne Vulgaris (5) Skin Disorders Associated with Malignancy (4) Malignant Melanoma (4) Pyoderma Gangrenosum (4) Shin Lesions (4) Bullous Pemphigoid (4) Pemphigus Vulgaris (3) Pityriasis Rosea (3) Pityriasis Versicolor (3) Molluscum Contagiosum (3) Keloid Scars (3) Pompholyx (3) Hereditary Haemorrhagic Telangiectasia (3) Dermatitis Herpetiformis (3) Porphyria Cutanea Tarda (3) Skin Disorders Associated with Pregnancy (3) Skin Disorders Associated with Diabetes (3) Squamous Cell Carcinoma of the Skin (3) Venous Ulceration (3) Hirsutism and Hypertrichosis (3) Zinc Deficiency (3) Alopecia (2) Alopecia Areata (2) Vitiligo (2) Erythema Ab Igne (2) Retinoids (2) Basal Cell Carcinoma (2) Guttate Psoriasis (2) Actinic Keratoses (2) Erythema Multiforme (2) Keratoacanthoma (2) Stevens-Johnson Syndrome (2) Acanthosis Nigricans (2) Impetigo (2) Skin Disorders Associated with Tuberculosis (1) Yellow Nail Syndrome (1)

Fungal Nail Infections (1) Lichen sclerosus (1) Granuloma Annulare (1)

CLINICAL SCIENCES Screening Test Statistics (19) Significance Tests (14) Turner’s Syndrome (11) Numbers Needed to Treat and Absolute Risk Reduction (10) X-Linked Recessive & Conditions (10) Gastrointestinal Hormones (10) HLA Associations (8) Complement Deficiencies (8) Study Designs (8) Hyperlipidaemia (8) Hypocalcaemia (7) Hypersensitivity (7) Normal Distribution (6) Odds and Odds Ratio (6) Respiratory Physiology (6) Hyponatraemia (6) Hypokalaemia (6) Down’s Syndrome (6) Cell Organelles (6) Mitochondrial Diseases (5) Cystic Fibrosis (5) Cardiac Action Potential (5) Homocystinuria (5) Familial Hypercholesterolaemia (5) Confidence Interval and Standard Error of the Mean (4) Bias (4) Relative Risk (4) Cell Cycle (4) Cell Division (4) DiGeorge Syndrome (4) Vitamin B (4) Immunoglobulins (4) Interferon (4) Autosomal Dominant & Conditions (4) Membrane Receptors (4) Antibiotics (4) Molecular Biology Techniques (4) Cell Surface Proteins (4) Inherited Metabolic Disorders (3) T-Helper Cells (3) Autosomal Recessive Conditions (3) Oncogenes (3) Dermatomes (3) Troponin (3) Cranial Nerves (3) Polymerase Chain Reaction (3)

Ricketssiae (3) Helminths (3) HIV (3) Cranial Nerves (3) Cytokines (3) Antidiuretic Hormone (3) Incidence and Prevalence (2) Upper Limb Anatomy (2) Patent Ductus Arteriosus (2) Ulnar Nerve (2) Cardiovascular Physiology (2) Campylobacter (2) Renal Anatomy (2) Trinucleotide Repeat Disorders (2) Metabolic Alkalosis (2) Renin & Renin-Angiotensin-Aldosterone System (2) Brain Tumours (2) p53 (2) Fitness to Fly (2) Pulmonary Surfactant (2) Congenital Infections (2) Vitamin C Deficiency (2) Immune System Cells (2) Endothelin (2) Sleep Stages (2) Breastfeeding: Contraindications (2) Eschericia Coli (2) Vitamin D (2) Fibrates (2) Renal Stones (2) Anderson-Fabry Disease (2) Herpes Simplex Virus (2) Renal Tubular Acidosis (2) Iron Metabolism (2) SIADH: Causes (2) Hyperkalaemia (2) Tumour Suppressor Genes (2) Rickets (2) Patients Who Refuse Treatment (2) Prader-Willi Syndrome (2) Atrial Natriuretic Peptide (2) Vitamin K (2) Foramina of the Skull (2) Anaesthetic Agents (2) Acute Phase Proteins (2) Epidermis (2) Achondroplasia (2)

PHARMACOLOGY & TOXICOLOGY Metformin 15) Paracetamol Overdose (13) Pharmacokinetics (9) P450 Enzyme System (9) Heparin (9) Monoclonal Antibodies (8) Tricyclic Overdose (8) Lithium Toxicity (8) Ciclosporin (7) Adrenoceptors, Agonists & Antagonists (7) Cocaine (6) Digoxin and Digoxin Toxicity (5) Antibiotics: Gross Mechanism of Action (5) Hypomagnesaemia (5) Tuberculosis: Drug Side-Effects and Mechanism of Action (5) Trastuzumab (5) Phosphodiesterase Type V Inhibitors (5) Ethylene Glycol Toxicity (5) Drug-Induced Impaired Glucose Tolerance (4) Quinolones (4) Carbon Monoxide Poisoning (4) Aspirin (4) Adrenaline (4) Drugs Causing Photosensitivity (4) Drugs Causing Ocular Problems (3) Drug-Induced Thrombocytopenia (3) Salicylate Overdose (3) Oculogyric Crisis (3) Therapeutic Drug Monitoring (3) Allopurinol (3) Combined Oral Contraceptive Pill (3) Cyanide Poisoning (3) Prescribing in Pregnant Patients (3) Drugs Causing Lung Fibrosis (3) Acute Intermittent Porphyria: Drugs (3) Octreotide (3) Methanol Poisoning (3) Flecainide (2) Calcium Channel Blockers (2) Side-Effects of Common Drugs: Anti-Anginals (2) Drug Causes of Urticaria (2) Amiodarone and the Thyroid Gland (2) Prescribing in Patients with Renal Failure (2) Organophosphate Insecticide Poisoning (2)

Haemodialysis in Overdose (2) Dopamine Receptor Agonists (2) Ecstasy Poisoning (2) Macrolides (2) Antiarrhythmics: Vaughan Williams Classification (2) Prescribing in Patients with Heart Failure (1)