hipotiroid kongenital dan penanganannya

8/3/2019 Hipotiroid Kongenital Dan Penanganannya

1/13

54974/43039,/,3!03,3,3,33,

ff@f

,:9,80/4907,3&3;0789,8789037/,,.,3,

,,37:3,&9,7,34,,79,-,7,9

/,7/*07,44.4/


2/13

,19,78

!

03/,::,3

3,2308,

!02078,,38

!02078,,3!03:3,3

0,,38

,3488

944

5/0244

!,9403088

!03,9,,8,3,,3

425,8

!743488

,34881107038,

!03:9:5

,19,7!:89,,


3/13

!03/,::,3

47243974/8,3,950393:39:209,-482003073:978/,34347,3

90724030888079,207,38,35079:2-:,3/,350702-,3,3-07-,,,73,3 !,/,

5074/0 798 :, :39: 50702-,3,3 8:8:3,3 8,7,1 5:8,9 /,3 9:,347243 3

202503,7: -0-07,5, ,73,3 /,3 80 20,: -07-,, 54, ,9;,8 0342 /,3

839088 574903 8079, 70805947 ,3 2025:3, ,79 50393 :39: -07-,, ,9;9,8

81:38 974/ 5,/, 2,8, -, /,3 ,3, /,5,9 -07,-,9 0,3,3 209,-4 ,3

/902:,3 5,/, /0,8, -07503,7: 5,/, 5079:2-:,3 /,3 50702-,3,3 ,703,

2,9:7,8 ,73,3 /,3 47,3 ,9,: ,73,3 85081 ,3 207:5,,3 503,9:7

50702-,3,3 -07,39:3 5,/, 010 47243 974/ 803, 4380:038 3

/81:38974/-07,39:35,/,:8,2:,92-:3,5,/,2,8,-,/,3,3,5,-,54974/820 5,/, ,33 ,9,: -, -,7: ,7 9/, /4-,9 2030-,-,3 0,3,3

39009:,/,3,9,:1:3830:744,320309,53203:3:,3-09,5,503933,

507,3 47243 974/ /,,250702-,3,349,8,,92,8, 90780-:9!,/,2,,,,3

8,,-:,93,,3/-,,89039,30,3,3.43039,5,/,003,7974/

3,2308,

3,23088 ,3 .072,9 5,/, 0:,7, /,5,9202-,39:2030,,3/,3488

/03,3 203,3,,3 ,5,, -: -07,8, /,7 /,07, 43/4 03/027,,9 897:2,

5,/, -: 7,,9 5034-,9,3 ,39 974/,9: ,2 ,9,: 9/, 7,,9 897:2, 5,/,

0:,7,/,350702-,3,3,3,%,35,,/,3, 87335,/,-,-,7: ,7 5,803

8073 /,9,3 907,2-,9 /03,3 0:,3 709,7/,8 50702-,3,3 /8079, /03,3,,

9:2-:,9,:507,,,3503/05,/,-,-,7:,78,25,:8,23:0:,39/,

85081


4/13

!02078,,38

!,/, 38508 ,,3/902:,3 /, -08,7:9 073 073,:2-., :-:3

:-:3 -08,7 0-,7 ,9,: 907,2-,9 203:9:5 :98 2,7242,9, 8:,7, 807, -, :7,3

,91!03,25,31880,880507983/742,/433,2:35,/,83/742,/43-,

0-,91!,/,8,,9/902:,35,8035,/,:2:23,9,25,5:.,9!,/, ,3,,3

0- -08,7 2:33 /902:,3 ,, -4/4 /, 202-08,7 709,7/,8 5079:2-:,3

/,3 9,3/,9,3/, 709,7/,8 2039, !,/, 702,, 5:-079,8 5704 /,5,9 907,/ /,3

2:33,/,502-08,7,380,9:78,/8,2535489:79:-:503/0

!02078,,3!03:3,3

!02078,,3 1:38 974/ % /,3 %$ /,:,3 :39:202,89,3/,3488

,5,-,/902:,3,/,7%703/,/8079,,/,7%$,32033,92,,/,3488

/,5,9 /90,,3 , .:9411 ,/,, a&2 , 3, %$ a&2 /,3,5

3472, ,/,7 %$ a&2 /,3,5 ,-3472, /,3 507: 502078,,3 38 /,3

502078,,3%$/,3%5,82,,,/,7%$93a&2/,3%703/,

a2 -,/-07 907,5 97483/,3/,:,3 502078,,3 0- ,3:9,/03,3

,/,7%$/,39,7,a&2/,:,3502078,,3:,323:02:/,3

!02078,,3/,7,50710703,5:39:203,,/,3,,3:,3420489,98

5,-, -: /.:7, 203/079, 54974/ 2,, -, 507: /5078, ,39-4/

,39974/ ,/,7 % /5078, -, ,/, /:,,3 /018038 % ,9: -, /03,3

472430974/9/,,/,708543

!02078,,37,/44,3/,:,3,39,7,,344745507:97,84347,1

9/,203:3,,37,/,857480/:73207:5,,3,9073,9;05079,2,,3/,3:7,3

:39: 503.97,,3 974/ 430 ,0 :39: 203, 5079:2-:,3 /,7 -, /,3 :39:

203039:,35030-,-3,2,,/,:,3502078,,38397,1003,7974/


5/13

!,/, 502078,,3 203:3:,3 503:7:3,3 042-,3 ! /,3 % /,3

42508"#$ ,32002,/,3203:3:,3503:7:3,3,9;9,8/,7-039707

/,301:8507.,7/:2

0,,38

0-,3,,3 ,3, /03,3 54974/ 43039, 0,, 38 5,/, 5074/0

3043,9, 8,3,9, ,7,3 ,9,: 73,3 /,3 9/, 85081 2085:3 907/,5,9 ,03088

003,7974/4259

07,9-,/,3/,3 5,3,3 ,7,/,, 3472, 909,5::7,305,,/,5,980/9

2033,9 ,703, 280/02, 49, 907:8 18448 ,3 -0705,3,3,3 ,3

/80-,-,3 40 2,9:7,8 :4743/ 43:,8 ,3 907,2-,9 2:33 207:5,,3

0,, 5,3 ,, 08:9,3 202-07 2,,3 907:9,2, 0,2-,3,3 :7,3 23,9

8423403 /,3 807,3,3 90780/, 8,,9 /7,,9 8073 2:3.: 80,2, :2:7 -:,3

5079,2,08:9,3-073,5,880-,,3,703,/,,3-08,79072,8:0584/0,530,

5073,5,8,3-07-:3/,3/:39078:2-,9$3/742/897085073,5,8,3,3,8:,

/,5,9907,/,,390703,80/9203,38-,3,9/:79/,8007,2,,3/,3

-,8,3, ,2-,3 :33 ,/, 43895,8 ,3 -,8,3, 9/, -0708543 907,/,5

5034-,9,3 !07:9 -08,7 /,3 -,8,3, ,/, 073, :2-,8 $:: -,/,3 8:-3472,

8073 /-,,/,3:9 907:9,2, 9:3,2:33/33 /,3-:724990/

/02,039,/,39:3,2:33,/,,/,2-,9-83,39:3,7/420,/,3

01:8 507,7/:2 ,825942,9 -,8,3, ,/, 302, 2,7489 8073 ,/, /,3

7017,907 907,/,5 5034-,9,3 /03,3 02,93 ,703, 0,,0,, 2:3.: 80.,7,

-079,,5/,34888073,907,2-,9

,31089,8 3 907:8 -0702-,3 #09,7/,8 50702-,3,3 18 /,3 2039,

203,/ 0--08,7 80,2,-:,3-:,3 -07:93,/,35,/,:8,-:,3,2-,7,3

38-0702-,380503:3,,,3,,/,/01803847243974/5,78,0,,3,

/,5,90-73,3/,3438093,907,2-,9085:3,78:8:-:203,3/:380:2,

47243 974/ 907:9,2, % 47243 3 9/, .::5 :39: 203/:3 -, ,3


6/13

203:8: /03,3 54974/820 43039, /,3 9/, 2025:3, 503,7: 5,/, :

8733974/3043,9:8

!079:2-:,3,3,907803/,90897029,8503/0/,3::7,305,,3472,,9,:

-,,32033,9439,30,,390747/,354890747907-:,0-,7 !03,2,9,39,3/,3

5,/, 8,,9 ,7 /,5,9 -07507,380-,, 50/42,3 ,, :39: 20303, 54974/820

43039,,3, -, -,7: ,7 3472, 202 1439,30,54890747 ,3 0-

-08,7/,7.2,9,3,9,25,90758,0-,7/,302-,9,3/:3,30-,7907,9

.0:38:7,5,50-7,80259/,3045,2,9,202-03,::9907-:,/,3/,

,3 90-, 8079, 0-,7 907::7 0 :,7!079:2-:,3 907,2-,9007503/0/,3

90-,907/,5,903/,5,302,/,9,8,;:,/,3/,39,7,007/,3-,:%,3,30-,7

/,3 ,7 503/0 :9 073 /,3 -0788 /,3 80/9 073,9 80/02, 9,25,

907:9,2,5,/,:9045,2,9,5:3:39,3,3/,3039,,089073,,7490302,

/,5,92030-,-,3,73,:9203,/:33909,5807,3,909,55:9:905,,

90-, /,37,2-:9 ,8,72:/, 5,9,/,3 958,78 7,2-:9203:7:3 ,:0-,,3

-,,/,,3-,8,3,9,25,20307:9907:9,2,09,-,203,38

!0702-,3,3 -,8,3, 907,2-,9 , 54974/ 9,25, 09,7 /,3 ,2-,3

/,,2-0,,7/:/:/,3 -07/7$:,7,3, 807,/,3 -, 9/,2,: -0,,7 -07-.,7,

%3,9 709,7/,8 18/,32039,2033,980,,3/03,3:8,3,,9:7,8808:,

/,5,9907,2-,9,9,:9/,907,/8,2,80,

949-,8,3,54943909,55,/,0,/,,3,3,7,3907,/580:/45079741

4949 2030:7: 83/742 4.070-70$020,30 83/7420 3, ,3 90703,

/,5,9 -07503,25,3 ,9098 ,703, 580:/45079741 907:9,2, 5,/, 4949 -098

!,94030883, -0:2 /09,: !07:-,,3 :97,897:9:7, /,3 8942, ,3 9/,

850819,25,5,/,-4584949,302-,3472,/03,35034-,9,3$3/7423

.03/07:3 -0702-,3 5,/,,3, ,, ,3 90, /,2,9 5,/, 8,:/,7, ,3/:3,3,7/,7507,3,380/,7, !03/079,203/079,54974/820,30-,2,

/,30--07,9


7/13

,3488

,3488/90,,3/03,3,3,2308,502078,,318/,3503:3,3&39:

,8:83/,348,3,,/,,54974/820.43039,

944/,3!,9403088

803088%74/07:5,,35030-,-907-08,754974/82043039,34303/027,

7,07:5,,3,-,9/,79/,,/,3,,73,3974/949,,03088,9,:5,78, 545,8, ,3/,5,9907,/,-,9,,3,503:7:3,3003,7 974/0

0070945/83/,5,9907,/,03088:3,907,,9,:545,8,,9470309

/,33:3,32:33-07507,35,/,/803088974/3,2:3/02,380-,,3

-08,75030-,-3,-0:2/09,:

0108390889748307:5,,30,3,3907-,3,43039,,703,0,3,30309010

,3//,5,9,3,/,,

O0,,,32034380397,8,3503,3,5,34/:2O01047,31,84/:2,703,0,3,3032%!,9,:5,/,0307,9388902

O0105,/,839088,9,:503,-:3,34/:2


8/13

O0105,/,/04/38,8

#088903%$$3/742 70889038 472430 -072,31089,8 8,3,9 :,8 80-,, ,-,9 /,7

-07:7,3 ,9,: 9/, ,/,3, 708543 03/ 47,3 907,/,5 472430 ,3 -448

,91, 3 /,5,9 /80-,-,3,703, /0105,/, 70805947,9,:5489 70805947%$

7088903 ,/,, 8:,9: 0,/,,3 003,7 974/ 701,907 907,/,5 7,38,3 %$

,33,1:3870805947%$ ,-,92:9,8 70805947%$ /010240:075,/,

80-,,30:,7,,8:8/03,37088903%$,3/9,3/,/03,3,/,7807:2%$

93/,3807:247243974/3472,,9,:203:7:3/8079,003,7974/3472,

,9,:545,89

$39088,9,:80708%$-07:7,354974/82 80397, /80-,-,3 ,703, 0,3,3 5,/, 54188 ,9,:

549,,2:8!,/,-,8,3,9,7,3/03,3570;,038,39,7,8,25,

0,7,3%$207:5,,38,,8,9:/,7-0-07,5,47243,3907,907,9

/03,3 47243457490354188,3 9078:8:3 ,9,8 8:-:39 -09,85081 /,3

,1, ,3 ,2 0-07,5,,8:8 54974/820 43039, 90, /,547,3 /03,3

,/,7%/,3%,3703/,/,3%$

,39,907::7/,,247243

/,3$

54188,35,/,,/,7,33427,!,/,8,9:1,2503,39,38:,9:-,8,/,,2

7045,/,038:-:39-09,2030-,-,3507:-,,3431472,943,,3

203.0,503,9,38:-:39-09,/,3,1,

03:7:33,97,385479%80:07$3/742 3 907,/ ,-,9 2:9,8 2434.,7-4,90 97,38547907 %

207:5,,3 1,89,94780:07 ,91 97,385479 472430 974/0/,,280 ,8,3,

5,/, , , 203,-,-,3 54974/820 /03,3 0,3,3 30:744 805079

0,2-,9,3 50702-,3,3 2030:7: /8943, 54943,80397, ,3:,3

5,3/,3,32,9,8079,,/,7%2033,9


9/13

#0889038472430974/07:5,,3 83/742 ,-,9 /,7 9/, 708543813, ,73,3 9,709 907,/,5

472430 974/ /9,3/, /03,32033,93, ,/,7% /,3 % /,,2 87:,8

/03,3,/,7%$80/92033,9,9,:3472,#0889038907,/,547243974/

9,25,3, -07-0/, ,39,7 ,73,3 /,3 /80-,-,3 40 .,.,9 70805947 39 %0,

/902:,3 24/:8 50,78,3 ,:94842, 708081 /,3 ,:94842, /423,3 ,3

203:3:,309074039,8,3:,33

3089,,34974033089 -,,3 497403 40 -: /,5,9 2032-:,3 43/4 ,33 /,3

54974/820 3043,9, -,9 3089 ,3 5,3 8073 ,/,, 4//, -,8,3,

/70805,3 /,,2 0850947,3 :39: 5034-,9,3 ,82, ,9,: 80-,, 5034-,9,3

974948488 2,9073, ,3, 4-,9 -, 503/079, ,82, 207:5,,3 1472:,8

42508 ,3 203,3/:3 -07-,, 803,, ,3 80.,7, 549038, /,5,9

20203,7: 1:38 974/ -: -,-, 3 -,8,3, 90, 203:3,,3 4//,

80,2,-079,:39,:39,35,203,,2502-039:,343/4,3-08,7/,38:/,

203,/0:974/80,2,0,2,3,33203,/8,3,9803891907,/,5907,/3,

54974/820 ,3 /3/:8 4//, 2:33 ,703, 20,3820 503:7,3,3

,2-,3 4//, 9474/ :3, 203425038,8 ,/,7 4//, ,3 5,82, 2,8

2,9:7 54974/820802039,7, :, /,8,3 40 ,:94,39-4/ 2,9073,

2030,970805947 %$ ,3 //,5,9 80.,7, 97,385,8039, !03::7,3 /,5,9

/,:,3 80-,, ,39-4/ 503,2-,9 503,9,3 %$ % %$ -3/3

3-93 ,39-4/08 ,9,: 80-,, ,39-4/ 5030,9 .! %$ % %$

-4.3 ,39-4/08 -:-: 3 -,8,3,202 974/98 ,9741,9: 5,7:

,39-4/ 5,/, 3043,9:78 809,7 23: /,3 54974/8203, /,5,9 20309,5

80,2,-:,3

!02-07,34/:27,/4,9180,2,0,2,35,/,907,5,307974/,9,:

507974/820 /,5,9207:8, 974/ ,33!,/, -,3, ,8:8 54974/820 ,3

/92-:,39/,//:,,/,3,0,2,38,,9502-07,3$09,5502-07,3


10/13

4/:2 7,/4,91 5,/, ,39, /03,3 :8, 70574/:91 ,7:8 //,:: 908

0,2,3

5/0244

38/0354974/43039,-07;,7,8,39,730,7,:2:23,80-08,7

0,7,3 /:5 03,3 5030-,- 9078073 ,/,, /803088 974/ ,3

203.,:5,8:80- 8073/902:,35,/,,3,507025:,3/,75,/, ,,

/03,3 507-,3/3,3 3, /03,3 83/742 43 202 7084 , 0-

93:39:203/079,54974/43039,/-,3/3,3,3472,38/0354974//

3/4308,/5077,,3,:0-93,9:80-08,70,7,3/:5 !70;,038

30-703/,5,/,207,074/,,2/,30-935,/,09:7:3,3

$5,34/,3207,,8/,,2

!030-,- 5974/ ,3 5,3 8073 / /:3, ,, /018038 4/:2 ,3

207:5,,3425430354497483%/,3974/497433%3,,3,7/,7

-:/03,3/018384/:2-07,9,,3203,,254974/,3 9/,907425038,8

,703,47243974/-:9/,/,5,9200,95,8039,

,3, 1,947 ,3 -07507,3 5,/, 54974/ 803, ,2-,7,3 383,

-07;,7,8%07,/3,54974/9/,/503,7:401,947047,18848,04342

2,:5:3 2 /,3 9/, 907/,5,9 570/08 :39: 443,3 0938 9079039: &2:23,

,8:8 974/ 43039, 92-: 80.,7, 8547,/ ,947 0309 ,3, -07507,3 5,/,

54974/9509079039:,3/9:7:3,380.,7,,:94842,708081

!03,9,,8,3,,3

0/,203948,

5,5:3 5030-,- 54974/820 907,5 503,39 /03,3 47243 974/ 80,:

/3/,8,3 /,3 01091 %74833,97:2 507 47, 207:5,,3 4-,9 5,3

5077,,3 97483 ,3-0787:,8 203,,2/04/3,8507107 203,/


11/13

974/497433 80-,,3 9 ,3 -0787:,8 -07,8, /,7 9 /,3 -:,3 ,38:3 /,7

003,7 974/,, 907,5 /03,3 974833,97:2,,3 203,,8,3 9 /,3 9

4885,/,-,,/,,2747,2,3,,30--08,79,25,3,20207:,3

809,72747,2/03,3/488,,2747,2,2

,/,79/,3%$,7:8/5,39,:907:8/,3/5079,,3,3/,,27039,33472,

,::/,3,5-,,97483:,/:3,,380-,,907,5503,392,,,/,79

,7:8/5079,,3,380/90-93:39:203425038,8/0180389909,53

/09,:-,,,/,793472,203,23,/,793472,

4320/,203948,

$:502039,8 4/:2 8,3,9 /-:9:,3 907:9,2, / /,07, /018038 4/:2

&2:23,,3,,3203/079,54974/43039,/,3203/,5,9705,.0203947243

974/ ,8:5,3 2,,3,3 ,3 203,3/:3 497403 ,7:8 /-,9,8 805079 ,85,7,:8

-,,2 -744:-8,.,3,.,3,3 4-, 8,,/, /,3 8:8:0/0, ,703,/,5,9

7303:7:3,3,-847-8$4/:2%7483

425,8

0,3,339009:,/,3,9,:1:3830:744,320309,5/,35079:2-:,3

,2-,9/,30,2-,9,32,9:7,89:,3

!743488

,807,3,/908/3/,3503.0,,3,3,/0:,9-07,39:35,/,:8,

2:,92-:3,5,/,2,8,-,,9,:,3,%,35,5034-,9,3503/079,-,/,5,9

2033,,-,9,/,3,4-897:85073,1,8,3,9,:3108503079,/,32070,,,3

/:5.0-4/03,3/080382039,%07,5/03,347243974/2032-:,3

5079:2-:,3307347,2,9:7,89:,3/,350702-,3,3808:,3,2:3

50702-,3,32039,:7,3/,5,9/7,2,,3


12/13

,34881107038,

$3/742043

0,3,3-,,,380,,7,3907,/5,/,/,39,7,-,43482,

438$3/7420/9,3/,400,3,3,,9,:.,.,92039,2:,/,7,380/,3

8,25, -07,9 %09,5 ,257 802:, ,3, ,3 203/079, 0,3,3 3 /,5,9 -0,,7

202-,., /,3 207,,9 /73, 803/7 $3/742 43,/,, 8:,9: :25:,3 0,,

,-,9 /,7 ,-3472,9,8 7424842 -,8,3, 7424842 ,3 9/, -07,8

2028,,3/780,2,20488803,907,/3/;/:/03,37424842

!/:2:23,-2434820 0-0./,30-73,3/,75,/,-,3472,

909,5 ,/, :,,32025,3,3/,3 -07,9 -,/,3 3472, 907:9,2, /,7,3

.::5:2:7!079:2-:,3 5489 3,9, 907,2-,9#09,7/,8 3 0- 3,9, 5/ 9,:3

5079,2, !03/079, 907,2-,9 /:/: -07/7 -07,,3 !,/, 9,:39,:3 -07:93,

5079:2-:,3,,-,,302:/,3709,7/,83,25, 0,802-, 80,2,5074/0

,/408.039 3, 2434820 8,3,9 275 8,9: /3 ,33, 804,4, ,,

-07,/,, 203:3:,3 0,, ,8 1,.08 24344/ /80-,-,3 40

5079:2-:,39:,3/,3,73,347,33900038,"703/,/49"2-0."/0-0"-,8,3,2-0.,9,:/49

!03:9:5

54974/ 43039,207:5,,3 ,3:,3 5079:2-:,3 003,7 974/ 80.,7,

43039, ,348854974/ 43039, /90,,3 -07/,8,7,3 ,3,23088 0,,

38502078,,318,-47,947:2/,38733$7335,/,54974/43039,

/,:,35,/,23: 5079,2, -, ,7 :39:203.0,425,8 ,3:9 $0,3

2,,,,38,,-:,98024,-072,31,,9


13/13

,19,7!:89,,

02,3 # 0843 909-44 41 50/,97.8

9

0/943!,/05,

$,:3/07880;07!

#:/454112,3#:/45::,,750/,97#:/45,,79,!

$09,9$!:73,2,8,7#3,/#,39,#2,5::2,8,,080,9,3/-:/,32:503,9/,,2,,79,&!

,,3930 ,3/7,3 ! 73843 2507038;0 50/,97. 4859,20/.30!,/05,48-80;07!

:43843,8,7/,8,750/,97/8,,79,!

hipotiroid kongenital dan penanganannya

Documents