histo on your nerves ssn histology october 26th, 2004 missy walker, maw2106@columbia.edu so young...

Download Histo On Your Nerves SSN Histology October 26th, 2004 Missy Walker, maw2106@columbia.edu So Young Kim, sk2298@columbia.edu

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  • Slide 1
  • Histo On Your Nerves SSN Histology October 26th, 2004 Missy Walker, maw2106@columbia.edu So Young Kim, sk2298@columbia.edu
  • Slide 2
  • Node of Ranvier Perikaryon Myelin- Producing Cell So whats in a nerve? Axon Hillock Dendrite Axon Terminal Axon Nucleus of myelin- producing cells
  • Slide 3
  • Axon vs. Dendrite Axon Dendrite NO Synthetic Machinery!
  • Slide 4
  • Nervous System Classifications
  • Slide 5
  • Spinal Cord
  • Slide 6
  • Spinal Cord: White Matter
  • Slide 7
  • Myelin Production in CNS Oligodendrocytes
  • Slide 8
  • Spinal Cord Gray Matter
  • Slide 9
  • Spinal Cord Cajals Silver
  • Slide 10
  • Meninges
  • Slide 11
  • Astrocytes No collagen in the CNS!!!
  • Slide 12
  • Brain
  • Slide 13
  • Cerebellum
  • Slide 14
  • Cerebellum
  • Slide 15
  • Purkinje Cell
  • Slide 16
  • Cerebral Cortex
  • Slide 17
  • Slide 18
  • Cerebellum vs. Cerebral Cx
  • Slide 19
  • Cerebellum vs. Cerebral Cortex
  • Slide 20
  • Pyramidal Cells vs. Spinal Cord Gray Matter
  • Slide 21
  • Peripheral Nervous System (PNS) Nervous tissue outside of the brain and spinal cord Somatic Nervous System Innervates skeletal muscle For conscious movement Cell bodies in CNS Autonomic Nervous System Innervates smooth muscle and glands For organ function and regulation Cell bodies in CNS and PNS Sympathetic & Parasympathetic
  • Slide 22
  • ANS - Ganglia Sympathetic GANGLIA in thorax contain: neuronal cell bodies satellite cells (support cells of the neuron) Synapses occur Presynaptic fibers myelinated Postsynaptic fibers unmyelinated
  • Slide 23
  • Enteric NS - Ganglia Myenteric plexus in ENS Within Smooth Muscle of Gut NO Collagen (as in CNS) Glial cells (no Schwann cells) Nuclei are euchromatic Gut has mind of its own
  • Slide 24
  • ENS Ganglion vs ANS Ganglion
  • Slide 25
  • Cross section of nerve Organization by Connective Tissues Endoneurium collagen fibers associated with individual neurons -Schwann cells within Perineurium layer(s) of connective tissue cells, create fascicles Epineurium dense cnxtive tissue binding fascicles into a bundle
  • Slide 26
  • Peripheral nerve Epineurium Perineurium Endoneurium
  • Slide 27
  • Periph nerve - longitudinal section Endoneurium Perineurium Epineurium
  • Slide 28
  • Longitudinal Section Cajal stain
  • Slide 29
  • Peripheral Nerve High Power (Cajal) Nodes of Ranvier Neurilemma (cytoplasm of Schwann cells) Whats the black?
  • Slide 30
  • Peripheral Nerve High Power (H&E) Whats the purple? Whats the white?
  • Slide 31
  • Cross Section Peripheral Nerve Whats the purple?
  • Slide 32
  • Peripheral Nerve Why is this a Nerve, not a Ganglion?
  • Slide 33
  • Key Points for PNS Ganglia Contain cell bodies for motor ANS Satellite cells are the supporting cell bodies (not glial, Schwann, or others of CNS) Peripheral Nerves Schwann cells make mylin sheath Node of Ranvier / saltatory conduction / Na channels Endoneurium around neurons, which form fascicles Perineurium around fascicles, which form bundles Epineurium around bundles
  • Slide 34
  • Same or different?
  • Slide 35
  • Slide 36
  • What are these?
  • Slide 37
  • Questions 1 & 2... A B
  • Slide 38
  • Question 3... Figure A Figure B
  • Slide 39
  • Question 4...
  • Slide 40
  • Question 5...
  • Slide 41
  • Question 6...
  • Slide 42