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Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis Imperfecta

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Page 1: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

Histology Unit 2 Seminar

Plan for tonight

Unit 3: Histology Project Topic Selection

Unit 2 Self-Assessment: Selected Questions (8)

Marfan Syndrome

Osteogenesis Imperfecta

Page 2: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

Unit 3 HISTOLOGY PROJECT PART 1:Topic, Outline and References

Topic Proposal: The topic should be on any of the systems covered in part 1 of this course (Histology) and be either a tissue or organ. This outline must be uploaded to dropbox by the end of Unit 3.

For the tissue or organ that you selected, you should:

• Describe the histological characteristics of the tissue or organ.• Correlate the structural characteristics of the tissue with their

function.• Discuss the importance of histological characteristics of the tissue or

organ to the body function as a whole.References: The document should also include the references that you used (at least 3 other than your book). For information on APA reference style please go to the Kaplan Writing Center.

Page 3: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question1Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Page 4: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question1Classify the following epithelial tissue marked with the arrows in the image below are:

Layer of flattened cells.

Basement membrane

What types of tissues are lined with this type of epithelium?

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Page 5: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question1Classify the following epithelial tissue marked with the arrows in the image below are:

Layer of flattened cells.

Basement membrane

What types of tissues are lined with this type of epithelium?

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Tissues that need broad membranes for molecular diffusion and filtration.

Kidney Bowman’s Capsules and Glomeruli.

Lung Alveoli

Page 6: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 2Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Page 7: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 2Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

What types of tissues are lined with this type of epithelium?

Basement membrane

Layer of cells as tall as they are wide.

Page 8: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 2Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

What types of tissues are lined with this type of epithelium?

Basement membrane

Layer of cells as tall as they are wide.

Protection, water-electrolyte balance (requiring active transport).

Covering of ovaries

Kidney Collection Tubules

Page 9: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 3Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Page 10: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 3Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Basement membrane

Single layer of cells attached to basement membrane. Uneven location of nuclei makes cells appear to be stratified.

What types of tissues are lined with this type of epithelium?

Page 11: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 3Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Basement membrane

Single layer of cells attached to basement membrane. Uneven location of nuclei makes cells appear to be stratified.

What types of tissues are lined with this type of epithelium?

Secretion and absorption

Lining of trachea and upper respiratory tract.

Page 12: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 4Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

Page 13: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 4Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

What types of tissues are lined with this type of epithelium?

Basement membrane

Multiple cell layers with cells furthest from the basement membrane becoming squamous.

Page 14: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 4Classify the following epithelial tissue marked with the arrows in the image below are:

Simple squamous epithelium

Simple cuboidal epithelium

Simple columnar epithelium

Stratified epithelium

Pseudostratified epithelium

What types of tissues are lined with this type of epithelium?

Protection:

Lining of esophagus (non-keratinized)

Protection and dehydration prevention:

Skin (keratinized)

Basement membrane

Multiple cell layers with cells furthest from the basement membrane becoming squamous.

Page 15: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 5This muscle type has nuclei located at the periphery of the cell.Skeletal muscle

Cardiac muscle

Smooth muscle

None of the above

Page 16: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 5This muscle type has nuclei located at the periphery of the cell.Skeletal muscle

Cardiac muscle

Smooth muscle

None of the above

Hints!

Mus

cle

Fib

er

Nuc

lei

Page 17: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 6This muscle type is the least able to regenerate in adulthood.Skeletal muscle

Cardiac muscle

Smooth muscle

None of the above

Page 18: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 6This muscle type is the least able to regenerate in adulthood.Skeletal muscle

Cardiac muscle

Smooth muscle

None of the above

This one you either know it or you don’t.

Page 19: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 7Epithelial tissue consists of:Aggregated polyhedral cells

Elongated contractile cells

Fixed and wandering cells

Neurons with elongated processes

Glial cells with elongated processes

Page 20: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Self-Assessment Question 7Epithelial tissue consists of:Aggregated polyhedral cells

Elongated contractile cells Muscle cells

Fixed and wandering cells Cells of the immune system

Neurons with elongated processes Nerve cells

Glial cells with elongated processes Support cells for nerves

Page 21: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Marfan SyndromeAbout Marfan Syndrome

Marfan syndrome is a disorder of the connective tissue. Connective tissue holds all parts of the body together and helps control how the body grows. Because connective tissue is found throughout the body, Marfan syndrome features can occur in many different parts of the body.

Marfan syndrome features are most often found in the heart, blood vessels, bones, joints, and eyes. Sometimes the lungs and skin are also affected. Marfan syndrome does not affect intelligence.

About 1 in 5,000 people have Marfan syndrome. This includes men and women of

all races and ethnic groups.

ReferenceNational Marfan Foundation (2011). Retrieved online from http://www.marfan.org/marfan/2280/About-Marfan-Syndrome

Page 22: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Marfan SyndromeWhat body systems are affected?Heart and Blood Vessels (Cardiovascular)* Enlarged or bulging aorta, the main blood vessel that carries blood from the heart (aortic dilation or aneurysm)* Separation of the layers of the aorta that can cause it to tear (aortic dissection)* “Floppy” mitral valve (mitral valve prolapse – MVP)

Bones and Joints (Skeletal system) * Long arms and legs* Tall and thin body type* Curvature of the spine (scoliosis or kyphosis)* Chest sinks in (pectus excavatum) or sticks out/pigeon breast (pectus carinatum)* Long, thin fingers* Flexible joints* Flat feet* Teeth that are too crowded

Eyes (Ocular system) * Severe nearsightedness (myopia)* Dislocated lens of the eye* Detached retina* Early glaucoma* Early cataracts

Other Body Systems * Stretch marks on the skin, not explained by pregnancy or weight gain * Sudden collapse of the lung (spontaneous pneumothorax)* Swelling of the sac around the spinal column (dural ectasia). This is found with CT or MRI scans of the back

ReferenceNational Marfan Foundation (2011). Retrieved online from http://www.marfan.org/marfan/2320/Features

Page 23: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Marfan Syndrome

Normal Medial Aortic Wall Marfan Medial Aortic Wall

Fibrosis (Collagen)

Layer

Spongiosa (Loose

Connective Tissue)

Layer

Ventricularis (Elastin) Layer

Ventricularis (Elastin) Layer

Page 24: Histology Unit 2 Seminar Plan for tonight Unit 3: Histology Project Topic Selection Unit 2 Self-Assessment: Selected Questions (8) Marfan Syndrome Osteogenesis

UNIT 2: Osteogenesis imperfectaBrittle Bone Disease

CauseDefect in gene that produces Type I Collagen.

SymptomsAll people with OI have weak bones, which makes them susceptible to fractures. Persons with OI are usually below average height ( short stature). However, the severity of the disease varies greatly.

The classic symptoms include: * Blue tint to the whites of their eyes (blue sclera) * Loose joints * Multiple bone fractures * Flat feet * Early hearing loss (deafness) * Poor teeth

Symptoms of more severe forms of OI may include: * Bowed legs and arms * Kyphosis (excess curvature of spine) * Scoliosis (S-curve (sideways curve) of spine)