history of the dan l. duncan cancer center 1997strategic plan recommendation 2002successful p20...
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History of the History of the Dan L. Duncan Cancer CenterDan L. Duncan Cancer Center
1997 Strategic plan recommendation
2002 Successful P20 application
2003-2005 Programs, shared resources, organizational structure, infrastructure
2006 P30 CCSG submitted Duncan gift
2007 NCI Cancer Center grant awarded
Mission of the Mission of the Dan L. Duncan Cancer CenterDan L. Duncan Cancer Center
• To provide exceptional patient care
• To provide outstanding education for students
• To conduct innovative research into the causes, prevention and treatment of cancer
• To provide community outreach and education, especially to the underserved
To prevent and ultimately cure cancer in all of its forms
Hospital Partnerships and Hospital Partnerships and
Patient Care ProgramsPatient Care Programs
Harris CountyHospital District
BCM Affiliates & FacilitiesBCM Affiliates & Facilities
BCM Clinic
Rice Consortium
Texas Children’s Hospital
St. Luke’s Hospital
Alkek Research Tower
Baylor College of Medicine
Ben Taub General Hospital
Michael E. DeBakey VA Medical Center
Research ProgramsResearch Programs
Cancer Biology Franko DeMayo, PhD
Molecular Carcinogenesis Janet Butel, PhD
Nuclear Receptors Orla Conneely, PhD
Breast Cancer Dan Medina, PhD
Cell and Gene Therapy Malcolm Brenner, MD, PhD
Prostate Cancer Tim Thompson, PhD
Cancer Prevention Powel Brown, MD, PhD
Pediatric Cancer David Poplack, MD
Membership and Grant SupportMembership and Grant Support
Total members 270
NCI Grant Support ≈$ 40M
Total Cancer Funding ≈$100M
SPOREs 3
Program Projects 5
U01 Mouse Models 4
U54 2
U19 2
LLS SCOR 1
U01 Redes en Accion 1
Developing ProgramDeveloping ProgramWorking GroupsWorking Groups
Gastrointestinal Cancer
Pancreas Cancer
Lymphoma
Melanoma
Gene sequencing of human tumors
Shared ResourcesShared Resources Genetically Engineered Mouse Franco DeMayo, PhD
Integrated Microscopy Mike Mancini, PhD
Protein Expression/Proteomics
Genomic Profiling ………………………
Biostatistics/Data Management
Clinical Trials Support Unit
Cell Processing/Vector Production
Dean Edwards, PhD
Lisa White, PhD and Eastwood Leung, PhD
Sue Hilsenbeck, PhD
Martha Mims, MD, PhD
Adrian Gee, PhD
Cytogenetics Core
Flow Cytometry
Rizwan Naeem, MD
Dorothy Lewis, PhD
Tissue Acquisition/ Pathology Tom Wheeler, MD
Other Baylor Core FacilitiesOther Baylor Core Facilities
• Bioinformatics Research Center
• Blot Analysis
• DNA Sequencing
• Interdepartmental Deconvolution Microscope
• Vector Development
• Mouse Phenotyping
Clinical ResearchClinical Research
• 4,000 new cancer patients diagnosed annually in partner hospitals
• 40% minority; 55% female
• 90 Investigator-initiated trials
• NCI-funded cooperative group membership- SWOG - COG
- NSABP - PBTC
- ACOSOG - CALGB
Nanoshell Treatment of Nanoshell Treatment of U373 Glioma CellsU373 Glioma Cells
Bare-NS Anti-IL-13r-NS
Live
Dead
PEG-NS
In press, Neuro-Oncology, 2007
Future Plans of the DLDCC in Future Plans of the DLDCC in Nanotechnology & NanomedicineNanotechnology & Nanomedicine
• Continue ongoing collaborations on nanotechnology projects with Rice and UT
• High priority for ongoing/future research
• Encourage faculty participation in the Keck Center Nanobiology Training program
• Encourage trainees to participate in training programs/projects in nanotechnology
• Commitment to space in the Rice Consortium building