how dna computers will work

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Search HowStuffWorks How DNA Computers Will Work by Kevin Bonsor NGS Sample Preparation magnamedics.com Mag. Bead cleanup, size selection reliable, easy, reduced costs NGS Sample Preparation magnamedics.com Mag. Bead cleanup, size selection reliable, easy, reduced costs Computer Electronics Home / Tech / Computer / Computer Hardware / Desktops MORE STUFF LIKE THIS 10 Ways 3D Printing Could Change the World How Transparent Texting Works Puzzle: Central Processing Unit 392 Tweet Tweet 48 36 739 Like Like Page 1 2 3 4 SURPASSING SILICON? Although DNA computers haven't overtaken siliconbased microprocessors, researchers have made some progress in using genetic code for computation. In 2003, Israeli scientists demonstrated a limited, but functioning, DNA computer. You can read more about it at National Geographic. DNA Computing Technology DNA computers can't be found at your local electronics store yet. The technology is still in development, and didn't even exist as a concept a decade ago. In 1994, Leonard Adleman introduced the idea of using DNA to solve complex mathematical problems. Adleman, a computer scientist at the University of Southern California, came to the conclusion that DNA had computational potential after reading the book "Molecular Biology of the Gene," written by James Watson, who codiscovered the structure of DNA in 1953. In fact, DNA is very similar to a computer hard drive in how it stores permanent information about your genes. Adleman is often called the inventor of DNA computers. His article in a 1994 issue of the journal Science outlined how to use DNA to solve a wellknown mathematical problem, called the directed Hamilton Path problem, also known as the "traveling salesman" problem. The goal of the problem is to find the shortest route between a number of cities, going through each city only once. As you add more cities to the problem, the problem becomes more difficult. Adleman chose to find the shortest route between seven cities. You could probably draw this problem out on paper and come to a solution faster than Adleman did using his DNA testtube computer. Here are the steps taken in the Adleman DNA computer experiment: 1. Strands of DNA represent the seven cities. In genes, genetic coding is represented by the letters A, T, C and G. Some sequence of these four letters represented each city and possible flight path. 2. These molecules are then mixed in a test tube, with some of these DNA strands sticking together. A chain of these strands represents a possible answer. 3. Within a few seconds, all of the possible combinations of DNA strands, which represent answers, are created in the test tube. 4. Adleman eliminates the wrong molecules through chemical reactions, which leaves behind only the flight paths that connect all seven cities. The success of the Adleman DNA computer proves that DNA can be used to calculate complex mathematical problems. However, this early DNA computer is far from challenging siliconbased computers in terms of speed. The Adleman DNA computer created a group of possible answers very quickly, but it took days for Adleman to narrow down the possibilities. Another drawback of his DNA computer is that it requires human assistance. The goal of the DNA computing field is to create a device that can work independent of human involvement. Three years after Adleman's experiment, researchers at the University of Rochester developed logic gates made of DNA. Logic gates are a vital part of how your computer carries out functions that you command it to do. These gates convert binary code moving through the computer into a series of signals that the computer uses to perform operations. Currently, logic gates interpret input signals from silicon transistors, and convert those signals into an output signal that allows the computer to perform complex functions. The Rochester team's DNA logic gates are the first step toward creating a computer that has a structure similar to that of an electronic PC. Instead of using electrical signals to perform logical operations, these DNA logic gates rely on DNA code. They detect fragments of genetic material as input, splice together these fragments and form a single output. For instance, a genetic gate called the "And gate" links two DNA inputs by chemically binding them so they're locked in an endtoend structure, similar to the way two Legos might be fastened by a third Lego between them. The researchers believe that these logic gates MOST WATCHED MOST POPULAR 10 DIY Projects for Tech Nerds How to Keep Your Laptop Cool 5 Ways to Troubleshoot Your Internet Connection Real Tech or 'Star Trek'? 10 Longestrunning TV Shows DON'T MISS Stuff You Should Know: Demystifying Your World Adventure Animals Auto Culture Entertainment Health Home & Garden Lifestyle Money Science Tech Video Shows Quizzes

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Search HowStuffWorks  

How DNA Computers Will Workby Kevin Bonsor

NGS Sample Preparationmagnamedics.com

Mag. Bead cleanup, size selection reliable, easy, reduced costs

NGS SamplePreparation

magnamedics.com

Mag. Bead cleanup, size selectionreliable, easy, reduced costs

Computer Electronics

Home /  Tech /  Computer /  Computer Hardware /  Desktops

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SURPASSING SILICON?Although DNA computers haven't overtakensilicon­based microprocessors, researchers havemade some progress in using genetic code forcomputation. In 2003, Israeli scientistsdemonstrated a limited, but functioning, DNAcomputer. You can read more about it at NationalGeographic.

DNA Computing Technology

DNA computers can't be found at your local

electronics store yet. The technology is still in

development, and didn't even exist as a concept a

decade ago. In 1994, Leonard Adleman introduced

the idea of using DNA to solve complex mathematical

problems. Adleman, a computer scientist at the

University of Southern California, came to the conclusion that DNA had computational potential after reading

the book "Molecular Biology of the Gene," written by James Watson, who co­discovered the structure of

DNA in 1953. In fact, DNA is very similar to a computer hard drive in how it stores permanent information

about your genes.

Adleman is often called the inventor of DNA computers. His article in a 1994 issue of the journal Science

outlined how to use DNA to solve a well­known mathematical problem, called the directed Hamilton Path

problem, also known as the "traveling salesman" problem. The goal of the problem is to find the shortest

route between a number of cities, going through each city only once. As you add more cities to the

problem, the problem becomes more difficult. Adleman chose to find the shortest route between seven

cities.

You could probably draw this problem out on paper and come to a solution faster than Adleman did using

his DNA test­tube computer. Here are the steps taken in the Adleman DNA computer experiment:

1. Strands of DNA represent the seven cities. In genes, genetic coding is represented by the letters A,

T, C and G. Some sequence of these four letters represented each city and possible flight path.

2. These molecules are then mixed in a test tube, with some of these DNA strands sticking together. A

chain of these strands represents a possible answer.

3. Within a few seconds, all of the possible combinations of DNA strands, which represent answers, are

created in the test tube.

4. Adleman eliminates the wrong molecules through chemical reactions, which leaves behind only the

flight paths that connect all seven cities.

The success of the Adleman DNA computer proves that DNA can be used to calculate complex

mathematical problems. However, this early DNA computer is far from challenging silicon­based computers

in terms of speed. The Adleman DNA computer created a group of possible answers very quickly, but it

took days for Adleman to narrow down the possibilities. Another drawback of his DNA computer is that it

requires human assistance. The goal of the DNA computing field is to create a device that can work

independent of human involvement.

Three years after Adleman's experiment, researchers at the University of Rochester developed logic gates

made of DNA. Logic gates are a vital part of how your computer carries out functions that you command it

to do. These gates convert binary code moving through the computer into a series of signals that the

computer uses to perform operations. Currently, logic gates interpret input signals from silicon transistors,

and convert those signals into an output signal that allows the computer to perform complex functions.

The Rochester team's DNA logic gates are the first step toward creating a computer that has a structure

similar to that of an electronic PC. Instead of using electrical signals to perform logical operations, these

DNA logic gates rely on DNA code. They detect fragments of genetic material as input, splice together

these fragments and form a single output. For instance, a genetic gate called the "And gate" links two

DNA inputs by chemically binding them so they're locked in an end­to­end structure, similar to the way two

Legos might be fastened by a third Lego between them. The researchers believe that these logic gates

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might be combined with DNA microchips to create a breakthrough in DNA computing.

DNA computer components ­­ logic gates and biochips ­­ will take years to develop into a practical,

workable DNA computer. If such a computer is ever built, scientists say that it will be more compact,

accurate and efficient than conventional computers. In the next section, we'll look at how DNA computers

could surpass their silicon­based predecessors, and what tasks these computers would perform.

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Add a comment 13 comments

Ethan Smith · El Centro College

Amazing wonderful yet horrifying information to know. No telling what governments would do tomanipulate the latest breakthroughs in advanced computing technology along withbiotechnology.

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Reply · Like · March 19 at 4:43pm

Vanitha Veluswamy · Works at Student

its an amazing technology.

Reply · Like ·   · September 14, 2011 at 9:58am2

Prashant Babu · Works at Uttam Galva Steels Ltd

hai

Reply · Like · October 1, 2011 at 9:28pm

Prashant Babu · Works at Uttam Galva Steels Ltd

u r looking very cute.

Reply · Like · October 1, 2011 at 9:28pm

Prashant Babu · Works at Uttam Galva Steels Ltd

add me as frnd

Reply · Like · October 1, 2011 at 9:28pm

Jishin Dev · Coorg Institute of Technology, Ponnampet

Truely and friendly saying, I thought of that once before.

Reply · Like ·   · April 24, 2011 at 7:09pm2

Raj Sharan · St.Paul's High School

but it will take too long.

Reply · Like · June 18, 2011 at 10:39am

Trust Okoroego · Lead Programmer at Digitrust nigeria

does that mean we are going to have up to gigahertz processor just the size of a cloth button.

Reply · Like · May 13, 2011 at 4:36am

J.d. Vader Nelson · 4 at 4

Holy crap, I can't stop thinking now.

Reply · Like · May 11, 2011 at 9:23am

Godar Jader · Chief Executive Officer at Awrosoft

Nice

Reply · Like · May 14, 2011 at 12:25pm

Indika Kalupahana · University of Kelaniya

there are no any note, or explanation about how to make the bio chip....

Reply · Like · April 25, 2011 at 9:26am

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