Human Physiology

Physiology 1 Section 3056 – Mon LabSection 3057 – Wed Lab

Dorena Rodedrode@santarosa.edu577-0379 8am – 8pm

Course Web Sitewww.dorenarode.com/physiology

Lecture notes Study guide Old tests Study questions Syllabus Links to other resources

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Why? To get email alerts, updates, and study

tips To take pretest (4 easy extra credit

points) Monitor grades Upload your student report

Course Requirements

Attendance at lecture and laboratory 11 quizzes (drop lowest two) 3 midterms Final

Mostly just a fourth midterm Small section cumulative final

Written/Oral Report Sign ups will be in lab

Lab assignments; lab quizzes More details later

How to study for this class

Use Chat Room to meet study partners

Science in Perspective

Everything

Truth

PhysiologyHow the Body Works

Web of Life

Whole Picture

Complex Whole

Scientific Knowledge

Science in Perspective

Exercise decreases resting heart rate

Aspirin decreases heart attacks

How the heart beats

Other heart related studies

Assumptions about heart

Scientific Method FOX pg 4-6

1. Observing natural phenomenon 2. Guessing “How”

(formulate hypothesis) 3. Design experiment 4. Do experiment 5. Collect/analyze data 6. Draw conclusions

Biological Organization

cells

Basic unit of structure and function in the body

tissues

Groups of cells with a similar function.

muscular

nervous

epithelial

connective

organs

Anatomical and functional units formed

by collections of the four tissue types.

Heart

Liver

Skin

systems

Collections of organs

that perform a common function.

systems

nervous

endocrine

musculoskeletal

circulatory

respiratory

urinary

digestive

immune

reproductive

integumentary

Homeostasis

State of dynamic internal constancy.

We maintain homeostasis by using negative feedback mechanisms.

Sensor EffectorIntegration Unit

Set Point

Sensor EffectorIntegration Unit

Set Point

Essential Parameters

heat (measured as temperature) pH oxygen ion concentrations water blood pressure glucose

pH regulation

What is pH?

pH = -log [H+]

As hydronium ion concentration goes up the pH goes down.

pH regulation

Why do we control pH?

Chemical reactions happen at only certain pH

Proteins are active at certain pH

pH regulation

How do we control pH?

1. Normal plasma pH = 7.42. Bicarbonate buffers small changes in pH3. We do something and pH drops4. Change in pH is detected by sensor

(aortic and carotid bodies)5. Signal sent to control center

typically either a hormone or nerve impulse6. pH value compared to set point7. If outside set point range, then a signal is sent to an effector

Effectors are typically a muscle or gland. Once activated the cells react to the stimulus and typically produce either a protein or release vesicles.

8. Effectors involved in pH regulation:pulmonary system, renal system, bones

Lab this week: Lab 1 Lab 2(skip question 5) Should Bill buy Sammy?