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    MARKET ASSESSMENTCASE STUDY :

    HYPERTENSION

    Presented By :Vartika Yadav BM 13

    Tanvi Patil BM 18Gargi Indurkar BM 20

    Pooja Jadhav BM- 21Shweta Bansal BM - 23

    Presented To: Prof. Suhas Tambe

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    Objective

    To find out the potential patient poolof hypertension for a leadingpharmaceutical company in five

    European Union countries.

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    Overview :Introduction

    Hypertension / HTN HighBlood Pressure or ArterialHypertension.

    Chronic condition, blood pressure inarteries is elevated.

    BP : classified by two measurements.

    Systolic : Blood pressure within range of100-140 mmHg.

    Diastolic : Blood pressure within range of

    60-90 mmHg.

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    Hypertension is also classified : Primary (essential)and Secondary hypertension.

    Primary Hypertension : 90-95% cases , which meanshigh bp with no underlying medical cause.

    Secondary Hypertension : 5-10% cases, caused by

    other conditions that have an effect on kidneys,arteries, heart or endocrine system.

    CLASSIFICATION

    SYSTOLICPRESSURE

    DIASTOLICPRESSURE

    mmHg kPa mmHg kPa

    Normal 90119 1215.9 6079 8.010.5

    Prehypertension 120139 16.018.5 8089 10.711.9

    Stage 1 140159 18.721.2 9099 12.013.2

    Stage 2 160 21.3 100 13.3

    Isolated systolichypertension

    140 18.7

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    Causes

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    Symptoms

    P

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    Prevent on anManagement

    Maintain normalbody weight .

    Reduce dietary

    sodium intake. Engage in regular

    aerobic physical

    activity such asbrisk walking.

    Limit alcohol

    consumption to no

    Lifestylemodifications

    Medications

    Drug Combinations:viz,

    calcium channelblockers anddiuretics, beta-blockers and

    diuretics,

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    Epidemiology

    Source : JAMA. 2003;289(18):2363-2369. doi:10.1001/jama.289.18.2363

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    Prevalence : Age

    The prevalence in the age group 35 to 44 years was 14% in the North American countries and27% in Europe, increasing to 53% and 78%, respectively, among persons aged 65 to 74 years.

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    Prevalence : Mortality

    Source : JAMA. 2003;289(18):2363-2369. doi:10.1001/jama.289.18.2363

    C lid t d ti t l d

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    Consolidated patient pool andepidemiology of

    hypertension(2011)Country Incidences Total

    PopulationPatient pool

    UK 41.7% 5,83,54,430 2,43,33,797

    Spain 46.8% 3,94,78,150 1,84,75,774

    Germany 55.3% 8,20,12,000 4,53,52,636

    Italy 37.7% 5,68,62,800 2,14,37,275

    France 29.7% 5,80,26,000 1,72,33,722

    ConsolidatedPatient Pool

    43.03%29,47,33,380

    12,68,33,204

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    Population vs. PatientPool

    0

    1

    2

    3

    4

    5

    6

    7

    8

    910

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    MARKET ESTIMATION

    The markets of the developing world are alteringmore radically than those of the developed worldHypertension (>1B patients by 2025)Diabetes (84m in 1995 to 228m in 2025 >70M in India

    alone)

    By the 2020 the global Pharmaceuticals marketwill be worth about $1.3 Trillion ($800Billion today)