ibm aspera in life sciences

© 2014 IBM Corporation

IBM Aspera in Life SciencesMoments matter.


Agenda

Disruption for the Life Sciences Industry

Why IBM Aspera is the Right Response to Industry Change

Executive Life Sciences Agendas for IBM Aspera

Why IBM is the Right Choice for Life Sciences

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petabytes (1015 bytes) of data being currently stored at the European Bioinformatics Institute in the UK; the genomic data doubling in size each year.1

DISRUPTOR: Big data and the cloud explosion has arrived for Life Sciences executives

“Aspera is the industry standard for the

transport and management of large

data files produced by life sciences.”Sifei HeCloud Product Director, BGI

genomes per week being generated today at $1000 each. The first human genome mapped in 2002 took 20 institutions working together for 13 years and cost $3 billion. Each genome is approximately 3 billion nucleotides. 2

of enterprises face significant roadblocks that hold them back from moving beyond cost reduction to faster time-to-market and better orchestration of their businesses.4

is the amount of server workload that will be virtualized in the cloud by the end of 2014. Cloud growth rates are 5x normal IT growth rates.3

20 60% 83%

3

300+


DISRUPTOR: Three quarters of Life Sciences enterprises have a weak digital-physical strategy – or none at all

Integrated digital-physical strategy

Limited digital strategy

No digital strategy

Source: Question B4–What kind of digital strategy does your enterprise have?; Global n=2,869; Life Sciences n=95 14

28%

51%

21%

have an integrateddigital-physical

strategy

Life Sciences

Digital Strategy

21%

Collaborative research teams that are geographically dispersed need to swiftly communicate and collaborate with one another as well as with third-party commercial or academic research groups.

31%

Underperformers

39%

Outperformers

85%increase

Integratingthe digital backbone to “customer”

effecting systems reaps rewards

Benefits of Integrated Digital Strategy


DISRUPTOR: Life Sciences CxOsunderstand the need to collaborate more extensively across internal and external boundaries in the future

Source: Question B2–How strong is your collaboration with partners/suppliers and employees?; Global n=1,390; Life Sciences n=95 to 97 15

39% of outperforming Life Sciences enterprises promote the development and usage of employee networks. Only 31% of underperforming enterprises do.

Partners/suppliers Employees

48% 84%

Today 3–5 Years

34% 82%

Today 3–5 Years

47% 48%

84%

34%

82%

141%

High level of collaboration with partners and employees needed

75%increaseincrease


DISRUPTOR: Industry Leaders are Struggling with Synchronization and Timely File Transport

Does your company have the ability to synchronize its critical internal and external systems?

6

of organizations regard synchronization as critical to their overall success …

17%

83%

Yes, encompassing everyone

No, not with everyone

3%

34%

73%

Not critical Neutral Critical

Value chain synchronization

survey – Feb, 2012 for IBM

… however, only cansynchronize their internal and external systems to drive business performance and success

17%73%


Agenda

Disruption for the Life Sciences Industry




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IBM Aspera Solutions Add Key Capabilities In IBM’s Market Leading Data Movement and Managed File Transfer Capability

Community-Centric

Multi-protocol edge gateway for universal connectivity to the

business community

Person-Centric

File sync and share

Emerging Use Cases

Governance

Security Common perimeter services, proxy and authentication

Actionable visibility for business, operations and compliance

Direct to Cloud …

System-Centric

Automated, reliable, secure transfers for system integration

High-Speed Large file/data set transfer and sync

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Smarter Commerce: IBM Aspera Capabilities Resolve Life Sciences Imperatives

R&D Transformation• Collaborative Research and Data Set

Sharing• Data transfers

"With Aspera, we get a full suite of solutions that accelerates almost every aspect of our highly customized workflows, giving us a key strategic advantage over others...” 1

- VP of Infrastructure & Technical Services

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Improve R&D

Processes


of organizations report they arechallenged to move big data quickly andefficiently enough to meet business requirements. 1

Smarter Commerce: IBM Aspera Capabilities Accelerate Business Value with Cumulative Benefits

According to a recent study, IBM Smarter Commerce pays back $12.05 USD for every $1 USD spent. 4

bandwidth utilization by FTP on high speed lines over distance without IBM Asperatechnology. 2

The number of hours it now takes to setup for large file projects, down from 2-3 weeks without IBM Asperatechnology. 4

Transcontinental file transfer speed improvements after deploying a High Speed File Transfer & Sync with no hardware or network upgrades required. 3

88% 100x<3% 2-3

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Agenda

Disruption in the Life Sciences Industry




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IBM Aspera for Chemicals & Petroleum Operations and Technology

Executives

ImproveR&D

Processes

High Speed Data Sharing & Distribution

High Speed Worldwide Data Transfer

COO

Collaboration Leader

Quality Assurance Lead

________________________

CTO

Research Ops Lead

B2B Integration Leader

________________________

FSS HFT

Eliminate the bottlenecks of traditional TCP and

physical data transport solutions by enabling

ultra-secure IBM Aspera High-Speed File Transfer

(HSFT) on premise and on the cloud to accelerate transfers to dislocated research and analysis

facilities and data centers.

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Increase flexibility and just in time

collaboration capabilities of local and

remote teams and personnel allowing

highly secure mobile, web and desktop access to all assets through the IBM Aspera File Sharing

Suite (FSS).

HSS

Utilizing IBM Aspera High Speed Sync (HSS) for

extremely fast and efficient cloud, data

center and on premise and off-shore/remote

synchronization for sharing, distribution and

disaster recovery.

High Speed Data Center & Cloud Sync

CIO

Cloud Systems Leader

VP of Data Centers

________________________

© 2014 IBM Corporation© 2014 IBM Corporation13

TOFROM

FSSHIGH SPEED DATA SHARING

AND DISTRIBUTION

SmarterCommerce B2B

Inconsistent

& Slow

Coordinated

& Fast


reduction in transmit time from days to minutes

reduction in cost in physical shipping and transportable

hardware costs

FSS HIGH SPEED DATA SHARING & DISTRIBUTION

As provider bioinformatics and healthcare data collection and processing, a better file transfer solution was needed that could integrate directly into the tumor research consortium web portals and that would provide fast transfer speeds, security, and data integrity.

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genomic research


Information Needs To Be Coordinated With A Growing Set of Participants:

Big data analytics team and software engineers

External partners, researchers and

educational institutions

Journal audit and

review team

Mark Has To Deal With A Growing

Set Of Data Types As Well:

QA scientists at experiment origin

Experiment design and process scientists

Genome re-sequencing, targeted re-sequencing, RNASeq, small RNA and De novo assembly files

Sensor and experiment machinery logs

Large database sets for neuroscience,and systems biology data

Video and imaging studies


Speed and security issues hamper most file sharing solutions today – IBM Aspera File Sharing Suite with FASP™ technology addresses all these issues and more to help collaborators do more. Faster.

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

MORE

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LIFE SCIENCES DATA FILE SIZES AND VOLUMES ARE EXPLODINGFOR EXECS LIKE MARK


WITH THE POWER OF IBM ASPERA FILE SHARING SUITE MARK HAS TOOLS TO COLLABORATE AT SPEED WITH HIS EXTENDED QUALITY ASSURANCE TEAM

Browser plugin or installed desktop or mobile app

Supports significant files sizes including big data analysis, genomic and bio-

informatics research.

DESKTOP & BROWSER

ACCESS

MULTI PROTOCAL

SIGN ON SUPPORT

LARGE FILE SUPPORT AT

SPEED

APIs FOR SEAMLESS

WORKFLOW

FSS can be integrated to

existing collaboration

systems

Easily integrated

into mobile and cloud platform

solutions.

All files for shared

individuals and teams can be synced across

all access points

FSS

Supports local (SAML) or managed (LDAP) login compliance

or both.

Provides encrypted

transfers and

federated data access

HIGH SPEED DATA SHARING & DISTRIBUTION

Accelerate the sharing of information between people, systems and communities and provide high performance distribution and synchronization of large files while lessening the security risk from sharing file based information

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

MORE

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THE IBM ASPERA FILE SHARING SUITE HELPS MARK’S TEAM COMPLY FASTERWITH NEW RESEARCH DEMANDS AND IMPROVED USER EXPERIENCE

Mark is the QA executive lead for a genomic research analysis and distribution company working with a large research consortium on new cancer experiments.


IBM Aspera File Sharing Suite creates a new paradigm of speed and agility

for sharing between life sciencesprofessionals.

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

MORE

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QUALITYASSURANCE

Mark can quicklycreate a new shared space

for the research team that is secure and easily accessible from

mobile, web or integrated into existing collaboration solutions.

Safety reports and video analysis of experiment operations are now able to be sent across the satellite uplinkin record time for review and analysis.

External researchers and data partners are able to download large files without worrying about older versions or extra versions being sent via e-mail since everything is consolidated and versioned.

Research teams can access reports requiring design changes and can securely exchange experimental filesfor improved and updated machinery and operations improvements quickly and easily.

With individual user

authentication and file history

and auditing the QA organization has a complete

history of document

creation and retrieval.


FASP TECHNOLOGY IS THE SECRET SAUCE THAT MAKES IBM ASPERA FILE SHARING SUITE UNMATCHED FOR LIFE SCIENCES TEAM COORDINATION

Bit AES encryption in which the key is re-initialized throughout the duration of the transfer using cipher feedback to protect against all standard attacks.

Reduction in transfer times –transfer that was taking 20 minutes now less than 1 min

Increase in total data shared per day - from 5GB to 190GB

HIGH SPEED MARKETING COORDINATION

IBM Aspera’spatented FASP transport technology is a proven standard for the high-speed movement of large files or large collections of files over wide area networks (WANs).

FSS

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

MORE

20x

38x

128

18


TOFROM

HFTHIGH SPEED WORLDWIDE DATA

TRANSFER

Limited &

Inefficient

Boundless &

Efficacious

SmarterCommerce B2B


Increase in speed over FTP for file delivery across the

WAN

600%A research center North America that uses the powerful tools of genomics and bioinformatics to understand, study, and generate data for the international scientific community needed a faster and more secure way to distribute 20GB+ data sets internationally than physical shipments.

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“Using Aspera, we don’t have to handle and ship drives. We can move all the data online. We have gone from spending 4 hours packing disks to 5 minutes using Aspera.” –Senior Software Engineer

global transfers

HIGH SPEED WORLDWIDE DATA TRANSFERHFT


LIFE SCIENCES OPERATIONS EXECUTIVES LIKE BRYAN ARE FACING LARGER FILE SIZES AND CONSTRAINED BANDWIDTH OPTIONS

US National Center for Biotechnology Information in Bethesda, Maryland. Each day last year, the EBI received about 9 million online requests to query its data, a 60% increase over 2011. 1

Analysis locations today can be 1000s of kilometers away from researchers.

Next-Generation Sequencing means larger data sets than ever before 2

Researchers like BGI have over 150 genome sequencing instruments working around the clock generating massive amounts of data for analysis. 1

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HIGH SPEED WORLDWIDE DATA TRANSFER

New research technologies create tens of gigabytes of data for each experimental run. Aspera software moves these large genomic data sets across the globe, achieving max transfer speeds and enabling more productive research and faster time to market.

HFT

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

MORE


IBM ASPERA HIGH SPEED FILE TRANSFER HELPS BRYAN’S ORGANIZATION UNLOCK LIMITS TO FILE TRANSFER SPEED AND DISTANCE

Bryan’s team can utilize web, mobile, desktop or server clients for ingestion to the cloud, local storage or both.

Transfer distances and bandwidth become non-issues with 99% network utilization.

Transfer large file sets like genomic data from experiments up to 1000x faster than before.

Security is a high priority at life sciences firms and Bryan can take comfort that his solution is compliant.

TRANSFER

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

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• File workflow and routing

• Advanced user and server management

• Complete monitoring and reporting

• High-availability configuration (active/active or active/passive)

• Extensive API support for embedding into existing transport solutions

HFT

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IBM ASPERA HIGH SPEED FILE TRANSFER HELPS BRYAN’S TEAM PROVIDE BETTER RESEARCH EXPERIENCES THAN EVER BEFORE

Bryan’s team is supporting a new medical research operation in Africa for a new client. The location is remote and connectivity is limited to VSAT and 2G cellular services. Physical transport of collected data is too expensive and takes too long to meet SLA requirements.


HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

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SUPER COMPUTING

RESEARCHCENTER

Bryan’s team does not have the budget or the time to make any significant improvements to his

company’s physical network hardware or cable infrastructure

but they must move all the research data for analysis within

12 hours after collection to meet SLA deadlines.

Security requirements for the content is at an all-time high as world reaction to mis-communicated data is a concern and overall security is regulated by the local and international governments.

Bryan’s group decides to deploy the IBM Aspera High Speed File Transfer solution in order to overcome bandwidth limitations with traditional FTP file transfers and maximize the network they have.

The team is able to deliver very large data sets, imaging and video for analysis and research to their data centers all over the world in record time.

Bryan’s team now has the ability to

move huge (100GB+) data sets faster and more securely than

ever before to cloud or directly to the companies super

computing data centers for analysis

around the world.

HFT


IBM ASPERA PATENTED FASP TECHNOLOGY DELIVERS BLISTERING SPEEDS REGARDLESS OF TRADITIONAL FILE AND NETWORK LIMITATIONS

Maximum transfer speed,

bandwidth utilization and maximum I/O

throughput on any storage

platform regardless of

number or size of files

HOW TO MAKE

IT HAPPEN:

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• Deployed across enterprise servers, private, public and hybrid clouds

• Powerful and flexible security model combining authorization, user management, and access control

• Search, filtering, and sorting capabilities

HFT

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FILE SIZEINDEPENDENT

DISTANCEINDEPENDENT

Transfer, replicate or synchronize your data in all types of scenarios: one-to-one, hub and spoke, unidirectional and multi-directional

INFRASTRUCTURE AGNOSTIC

Locate your big data anywhere and move it seamlessly with high-speed,

secure transfers

ANY DEPLOYMENT

MODEL

ON PREMISES CLOUDHYBRID


HSS

Speedy & Reliable

Sluggish & Unpredictable

SmarterCommerce B2B

TO

HIGH SPEED DATA CENTER AND

CLOUD SYNC


Weeks for full system implementation and turn up

average throughput on data transfer rates between

synchronized sites

Multinational company active in over 180 countries needed a way to synchronize petabyte sized file systems with 100s of millions of files across the country and around the world quickly and securely.

2

8Gbs

HIGH-SPEED DATA CENTER AND CLOUD SYNCHSS

disaster readiness


Reduce the time to send and

receive secure files even across remote or poor

data connections at

up to 1000x faster than

standard protocols like

FTP.

Cloud usage and sensor growth means Life Sciences must synchronize more data than

ever between data centers and user systems

Experiment photo/video, logs and sensor dump data archival

External partner/equipment manuals, firmware, updates, etc.

Data migration of NGS research for analysis and consolidation

Remote sync of data centers and servers for disaster

recovery

DATA SETS GET ARE GETTING BIGGER AND SCIENCE IS DRIVING MORE REMOTE LOCATIONS AND BIG DATA SERVICES

HSS HIGH-SPEED DATA CENTER AND CLOUD SYNC

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

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LARGE DATA

FILES & SETS


IBM Aspera Sync intelligently

recognizes changes and file system

operations, instantaneously synchronizing of

millions of files and multi-terabyte file

sets at multi-gigabit transfer speeds to remote peers with

encryption in transit and at rest that

assures maximum security of business-

critical digital assets.

IBM ASPERA HIGH SPEED SYNC DELIVERS FASTER, MORE RELIABLY AND MORE SECURELY THAN RSYNC

Exabytes of data are created

every single day across the globe

2.5 1000x

IBM Aspera High Speed

Sync is up to 1000 times faster than traditional

rSync

40%

Current per annum

growth rate in enterprise storage each

year

HSS HIGH-SPEED DATA CENTER AND CLOUD SYNC

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

MORE


IBM Aspera FASP technology is an

evolutionary leap in rapid file movement virtually eliminating time constraints and

throughput bottlenecks on even the most fragile and

underpowered networks.

IBM ASPERA HIGH SPEED SYNC GENERATES SIGNIFICANT SPEED IMPACTS WITHOUT ANY HARDWARE OR NETWORK ENHANCEMENTS

in network utilization.From 2% to 99% for file transfers.

Transfer that was taking 10 hours now takes 26 minutes.

in hardware and network upgrades. Aspera solutions are all software based.

20X + FASTER

$0 INVESTMENT

97%INCREASE

HIGH-SPEED DATA CENTER AND CLOUD SYNCHSS

HOW TO MAKE

IT HAPPEN:

DO

MORE

FASTERKNOW

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Agenda

Disruption in the Life Sciences Industry




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IBM is dedicated to your success, in your industry

Unparalleled

Industry Expertise

• Accelerate solution design and thorough business process expertise

• Reduce project risk with reusable implementation patterns and support for industry standards

• Providing services to the top life sciences organizations worldwide.

Extensive Industry

Support Community

• IBM partners with the top life sciences research organizations in the world to invest in innovative design, functionality, and integration

• Dedicated resources within Global Business Services with an average of more than 10 years of experience

• Services organization closely aligned with software products to effectively translate technology into business outcomes

Significant Technical

Investment

• Over $3 billion invested in the last 3 years to create a truly smarter approach to commerce

• Integrated products for easier implementation and increased speed to value

• Synchronized product roadmaps across software portfolio

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