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Purnima Menon, PhD Senior Research Fellow and Theme Leader for South Asia Nutrition Programs Kathmandu | May 17, 2017 Implementation science and research in nutrition scale up efforts

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Purnima Menon, PhD Senior Research Fellow and Theme Leader for South Asia Nutrition Programs Kathmandu | May 17, 2017

Implementation science and research in nutrition scale up efforts

Acknowledgements

§  Research collaborators o Rahul Rawat, Marie Ruel, Phuong Nguyen, Sunny Kim, Rasmi Avula, Kuntal Saha

(Alive & Thrive , POSHAN) o Shams El Arifeen and Masum Billah (icddr,b) & Stuart Gillespie and Andrew Kennedy

for work on Transform Nutrition §  Funding

o Bill & Melinda Gates Foundation for work on Alive & Thrive and POSHAN o DFID UK for work on Transform Nutrition

§  Other o David Pelletier and other members of the Society for Implementation Science in

Nutrition

Presentation objectives

§ Connect nutrition interventions to delivery platforms and define implementation research

§ Showcase examples of implementation research in nutrition § Reflect on challenges and opportunities in the context of addressing

wasting in South Asia

1. Definitions: Implementation research in nutrition

§  Interventions: Things we want to get out there o Iron-folic acid supplements o Zinc tablets with oral rehydration

salts o Information o Nutritional counseling o Food supplements o RUTF o Treatment protocols

§  Delivery platforms: Ways in which we can get things out there o Primary health center, well-child

check-up o Primary health center, antenatal

care o Community outreach program with

home visits by health workers o Mass media campaign o Facility-based platforms for

treatment

Defining terms

THE SITUATION IN SOUTH ASIA

Akseer  et  al.,  BMJ  2017  

No  standard  coverage  indicator  related  to  screening  or  treatment  for  severe  was3ng  

0  

10  

20  

30  

40  

50  

60  

70  

80  

90  

100  

%  

Sources: NFHS-4. RSoC data was used for indicators on pregnancy registration, food supplementation during pregnancy, lactating and for children, visits by health worker, pediatric IFA and deworming for children.  

SUBNATIONAL ANALYSES SHOW FURTHER VARIABILITY (COVERAGE BY STATE IN INDIA)

Menon  et  al  2017  

Data  from  coverage  indicator  related  to  screening/growth  monitoring  not  available  yet  

Characteris3cs,  Capaci3es    and  Dynamics    

Nutritional

Status

Enabling  Environment:  Government,    funders,  civil  

society,  private  sector  

ImplemenDng  organizaDons  

Clients,  households  

and  communiDes  

Frontline    workers,    

supervisors    and  

managers  

Nutrition Interventions

Nutrition Outcomes

But, why this gap?

The Black Box of

Implementation

Vitamin & Mineral Powder

Slide  credit:  D.  PelleDer  and  the  Society  for  ImplementaDon  Science  in  NutriDon  

Opening the Black Box of Implementation (Five Domains)

Nutritional Status

Adapted from Damschroeder et al., Implementation Science 4:50, 2009

1. Objects of Implementation

2. Implementing Organization(s) Frontline workers,

supervisors and managers

4. Individuals, households and communities

3. Enabling Environment: Government, funders, civil society, private

sector •  Nutrition-specific

interventions

•  Nutrition-sensitive interventions

•  National multisectoral agendas

•  NGO projects (usually sub-national)

•  Implementation innovations

5.

Implementation Processes

Initiation, Planning&Design, Implementation,

Sustaining

Slide  credit:  D.  PelleDer  and  the  Society  for  ImplementaDon  Science  in  NutriDon  

Adapted from Damschroeder et al.,Implementation Science 4:50, 2009

Implementation Outcomes

Client

Outcomes

2. Implementing Organizations

Objects (adapted) • Core components • Peripheral components

3. Enabling Environment and Stakeholder Dynamics:

Perceived and Actual: source, evidence, advantage, adaptability, trialability, complexity, design quality and packaging, cost

5. Implementation Processes  

Staff (frontline, supervisors and managers): •  Knowledge, skills, beliefs, motivation

and incentives, workload, self-efficacy, stage of change, values, intellect, competence, learning style, openness, access to materials and resources, accountabilities

SISN’s Five Domains of Implementation: Black Boxes Within Black Boxes

Needs, resources, capacities, social, cultural, behavioral, economic, political factors

1. Objects of Implementation

Organizational Characteristics: •  Leadership, commitment, readiness,

management, competing pressures and priorities, incentives, compatibility with mission, capacity and resources to adopt, adapt, implement, support, monitor and adjust, accountabilities

Government and donor policies, practices, resources & regulations, peer/ network influences, national, societal & cultural influences, accountabilities

4. Individuals, households and communities:

Intervention/ Innovation / Guideline/ Practice / Policy (unadapted) •  Core

components •  Peripheral

components

Initiating, Scoping & Engaging •  assessing fit and readiness with

opinion leaders, formal leaders, champions, facilitators, partners

Planning •  Theory of Change / PIP •  Formative research •  Design & adaptation •  Implementation strategy Implementation, Iterative Improvements & Scaling Up •  components, sequence, intensity •  duration, quality improvement, •  process evaluation, operations •  research, special studies •  decisions and adjustments Commitment, Support, Financing & Sustainability •  continuous advocacy, networking,

engagement, strategizing, vigilance, reporting and documentation  

AAA  

Pathway  to  impact  for  nutriDon  intervenDons  

INPUTS    (Domain  1)   PROCESSES   OUTCOMES   IMPACTS  

IntervenDon  design  &  

implementaDon  plans,  training  

content,  training  plans  

Choice  of  food/MN  

intervenDons,  ProducDon/  procurement  

           

(Domains  2,3)  Upstream  Processes  

 Management  capaciDes  Training  processes,    moDvaDons  

 ProducDon  capaciDes  

             

                 

(Domains  2,3)  Midstream  Processes  

 Supervision  &  management  processes  

 Supply  chain  for  foods/MNS  

           

(Domain  4)  Downstream  Processes  

 Frontline  capaciDes,  work  loads  

 Local  supply  chain/stock  

issues  Local  product  promoDon  

 (Domain    5)  Quality,  scale    

equity  of  service  delivery,  access  to  products  and  

food  

Contextual  factors  at  community  and  household  levels  affecDng  demand,  uDlizaDon,  adherence  and  sustainability,  including  

individual  capaciDes  of  user  communiDes    

(Domain  6)  UDlizaDon/  demand  of  

services,  foods  and  products  

(Domain  7)  IMPROVED  NUTRITION  BEHAVIORS  

 IMPROVED  

NUTRITIONAL  STATUS  

(Dom

ains  5,6)  

Coverage  /  Ad

herence  

BCC  Foods/M

Ns  

ENABLING  POLICY  ENVIRONMENTS  &  GOVERNANCE  

Strategies  for  demand  creaDon  ,    

sensiDzaDon,  advocacy,  

sustainability    

Contextual  factors  at  naDonal  and  organizaDonal  level  affecDng  implementaDon  and  sustainability,  including  

stakeholders  

*  Domains  1-­‐7  are  defined  below.    Menon  et  al.  gAnnals  of  the  NYAS,  2014  

“Implementation research is the systematic approach to understanding and addressing barriers to effective and quality implementation of nutrition interventions, strategies and policies (typically in specific contexts)”

(WHO/TDR Implementation Research Toolkit, 2014)

Implementation Research (IR)

What do implementation research studies on look like?

§ Formative research studies § Process evaluations nested in impact evaluations § Experimental studies with operational end-points § Stand-alone operational assessments § Responsive rapid studies/analytics § Costing studies § Creative routine monitoring § Implementation-focused analyses of secondary data?

Scaling up : nine key elements

1)  Clear  vision  and  goal  for  impact  

2)  IntervenDon  characterisDcs  3)  Enabling  operaDonal  

context  4)  Catalysts,  champions,  

ownership  5)  Relevant  pathways  

6)  OperaDonal  and  strategic  capaciDes  7)  Adequacy,  stability  and  flexibility  of  funding  8)  Enabling  policy  and  governance  system  9)  Mechanisms  for  learning  &  accountability  

Gillespie,  Menon  and  Kennedy,  Advances  in  Nutri/on,  2015  

Scaling up is highly dependent on operational contexts and implementation research needs to help shed light on the intersection Intervention complexity with implementation context complexity     Simpler  interven3on     Complex  interven3on  Simpler    context      

   

Vit  A  supplementaDon  through  campaign.    DistribuDon  of  micronutrient  powders  to  homes  through  NGO  plahorm  

Complex  (mulD-­‐component)  behavioral  change  communicaDon  intervenDon  through  community-­‐based  nutriDon-­‐focused  NGO  program  plahorm.    Agricultural  diversificaDon  intervenDon  through  nutriDon-­‐focused  NGO  program  plahorm  

Complex    context  

Vit  A/iron-­‐folate/calcium  supplementaDon,  nutriDon  counseling  through  mulD-­‐purpose,  mulD-­‐Dered  government  health  system  

Integrated  complex  behavioral  change  communicaDon,  micronutrient  supplementaDon  and  agricultural  extension  intervenDon  through  women’s  self-­‐help  groups  and  links  with    government  health  systems.    Integrated  con3nuum  of  care  (community  to  facility  and  back  to  community)  for  screening,  iden3fica3on,  referral,  treatment  and  follow-­‐up  and  management,  of  severe  acute  malnutri3on    through  mul3-­‐purpose,  mul3-­‐3ered  government  system  

Some challenges with implementation research

§ The best place to do this research is within and with programs being implemented.

§ Requires reconciling research objectives and values with program implementation objectives and values

§ Requires adequate funding for research on implementation and utilization of programs

§ Funding and publication bias can discourage relevant research.

§ Contextual factors are critically important, especially social, organizational and political contexts

2. Some examples of implementation research in nutrition

73.7  

90.9  

75.8  87.9  

32.1  

63.8  

30.0  

45.5  

6.3  12.4  

0  

20  

40  

60  

80  

100  

Baseline  2010   Endline  2014  %  Achieving  m

inim

um  diet  d

iversity  

VN  -­‐  Intensive   VN  -­‐  Non  intensive  BD  -­‐  Intensive   BD  -­‐  Non  intensive  ET    

Example 1. Results from behavior change intervention evaluations targeting infant feeding in Bangladesh, Ethiopia and Vietnam (children 6-23 months)

Bangladesh  context:  outreach  program,  household  food  diversity  &  resources  

Vietnam  context:  facility-­‐based  program  à  lower  reach  to  women  with  children  >6  mo  of  age;    high  at  baseline,  low  potenDal  to  benefit;  economic  constraints  on  food  purchase  were  low  

Ethiopia  context:    outreach  program,    low  household  food  diversity  and    resources  

18.9  

57.8  

17.8  

28.4  

48.5  

87.6  

51.2  53.5  

72.4  82.8  

0  

20  

40  

60  

80  

100  

Baseline  2010   Endline  2014  

%  Exclusiv

ely  breashed

 

VN  -­‐  Intensive   VN  -­‐  Non  intensive  BD  -­‐  Intensive   BD  -­‐  Non  intensive  ET    

Results from breastfeeding behavior change intervention evaluations in Bangladesh, Ethiopia and Vietnam (children 0-6 months)

Bangladesh  context:  outreach  program,  low  levels  of  women  in  work  force  

Vietnam  context:  facility-­‐based  program,  lower  reach,    high  parDcipaDon  of  women  in  work  force,  formula  markeDng  rampant  

Ethiopia  context:  outreach  program,  low  parDcipaDon  of  women  in  workforce  

45.1  

24.3  

11.3  

5.8  

13.5    No  visit    <  50%  recommended  visits  50  -­‐  74%  recommended  visits  75  -­‐  99%  recommended  visits  ≥  100%  recommended  visits  

Utilization of nutrition counseling at health facilities in Vietnam was less than optimal despite availability and quality [demand side constraints]

0-­‐5.9  months  

6-­‐23.9  months  

    (n=502)   (n=506)  Ever  seen  MTBT  logo   91.2   96.8  Ever  heard  the  name  of  MTBT    

77.3   88.1  

Ever  seen  an  invitaDon  card    

49.4   63.2  

Ever  received  an  invitaDon  card  

39.0   50.3  

Have  been  to  MTBT     47.6   62.1  Number  of  Dme  visited  MTBT  in  the  last  6  mos  

1.7±1.4   1.3±0.1  

Nguyen  et  al.,  2015  

Example 3: Multiple interventions, across the continuum of care, 2 major delivery platforms, (Odisha, India)

0  10  20  30  40  50  60  70  80  90  100  

Pregnancy   0-­‐6  months   6-­‐24  months  

Avula  et  al.,  2015  

INDIA NFHS-3 – had a question on weight measurements in the ICDS! Eighteen percent of children age 0-59 months in areas served by an anganwadi centre have had their weight measured in an AWC. Orissa is the only state where more than half of the children under age five were weighed in an anganwadi centre. There are 11 states where not even 10 percent of children in areas covered by an anganwadi centre were weighed in an AWC. With the exception of Bihar and Uttar Pradesh, all these states belong to the North and Northeastern regions. With 24 percent of children under age 5 being weighed, Himachal Pradesh is an exception in the northern region. Similarly, Meghalaya, Mizoram and Sikkim are exceptions in the northeastern region, as at least 23 percent children under age five are weighed in each of these three states.  

Example 4: Integrating nutrition interventions in routine health systems in Bangladesh: sick child visits

0  

10  

20  

30  

40  

50  

60  

70  

ObservaDon  of  service  delivery  

Weighed  and  recorded  weight  

Measured  and  recorded  height  

Clinically  diagnosed  for  SAM  

Demonstrate  IYCF  pracDce  using  visual  job  aids  

Checked  child's  weight  against  a  growth  chart  

Counselled  on  ensuring  Vitamin  A  capsule  

Give  age  specific  advice  on  inclusion  of  salt  in  complemetary  food  Used  BCC  materials  to  raise  awareness  on  nutriDon  

Counselled  mothers  on  food  and  care  required  for  underweight  children  

NutriDonal  assessment  

NutriDon    counseling    

N=>500  sick  child  case  management  observaDons  

Saha  et  al.,  2015;  Billah  et  al.,  BMC  Public  Health,  forthcoming  

§  Interventions o Challenges vary

tremendously by intervention type

o Even seemingly simple interventions have significant systems and capacity needs

o People must want the intervention (e.g., facility-based counseling is not usually demanded)

§ Delivery platforms o Reach and maturity of

the platform is critical o Ability to assure quality

and intensity differs by context, even for same type of platform

o Assuring intervention coverage even within “at-scale” delivery platforms require investments in monitoring, incentives and systems capacities

Reflections from implementation research I have been involved in

3. Approaching implementation research in the context of preventing and treating wasting

ISSUES TO CONSIDER IN IMPLEMENTATION RESEARCH ON WASTING PREVENTION AND TREATMENT

Con3nuum  of  preven3on  and  treatment  for  was3ng  

PrevenDon   IdenDficaDon   Treatment   PrevenDon  of  relapse  

How  to  effecDvely  deliver  prevenDve  acDons  to  address  undernutriDon  –  at  scale?    What  plahorms  work  best  to  reach  children  with  prevenDve  services?  

What  plahorms  and  approaches  integrated  into  plahorms  are  most  effecDve  to  support  screening  and  iden/fica/on?        What  metrics  (W/H  vs.  MUAC)  are  more  feasible  to  integrate?  

How  to  match  treatment  modaliDes  to  context?      How  best  to  integrate  treatment  with  prevenDon?  How  to  moDvate  and  support  staff  who  deliver  these  programs?  

How  best  can  we  set  up  supporDve  systems  to  prevent  relapse?    What  are  the  most  feasible  “graduaDon  criteria”?  

COSTING  STUDIES!  

Illustra/ve  ques/ons  

Closing thoughts § Tremendous opportunities and a great

need to invest in understanding how to support effective interventions both for prevention and treatment of malnutrition.

§  Implementation research, embedded in the systems of intervention delivery, can help identify ways to strengthen delivery

§ Key areas for wasting-focused implementation research are on integration with prevention, screening and identification, development and validation of coverage measurements, uptake and adherence, prevention of relapse, and more.

Photo:  P.  Menon,  2013,  Uzar  Pradesh  

An implementation research framework and agenda (2014)

FURTHER READING ON LINKING WASTING AND STUNTING