improved diagnostic test benefits children with acute myeloid

Improved diagnostic test benefits children with acute

myeloid leukemia and Molecular probes identify

changes in fibronectin that may lead to disease

MOLECULAR BIOLOGY

MARCOS RESTREPO ARANGOSECOND YEAR MEDICAL STUDENT

MEDELLÍN2013

Introduction The laboratory techniques that scientist are trying to improve are focus in the objetive of facilitate to the doctor the way of treatment of some disease by understanding the molecular compotation of these. So this way the patients are going to receive more effective’s treatment. Other one is to diagnostic rapidly the presence or the inition of a disease.


myeloid luekemia

The flow citometry is a technique that is use in laboratorys to find cells that

are extrange in a sample, that has 1000 cell. So the technique classified

the cancer cells from the normal cells.


myeloid luekemia

The idea of this technique is to improve it with the objective to

identify minimal residual disease. With identifying this minimal trail of

pathology it would be easier to focus the treatment and identify which

patients are allowed to receive some special handling.


myeloid luekemiaThe study also make a comparison of the methods that are usually used to

identify de ALL and AML. With the objective to identify which technique is better to handling the patients. The methods that the study compares are the evaluation by microscopy, the PCR

and the flow cytometry.


myeloid luekemiaAs result of the study the better was the flow cytometry. Because the PCR

has false positives result. The microscopy evaluation results very difficult to identify the cancer cells

from normal cells. And flow cytometry can detect de minimal

residual disease.


myeloid luekemia

Molecular probes identify changes in fibronectin that

may lead to disease

Know the knowledge of the microscopy things take more

importance in the medical world because the new explanation of the behavior of a disease. In these case the scientist are trying to find why

some malformation of the fribronectin fiber are related with

the development of some pathologies.


may lead to disease

The fibronectin fibers are related with the development of some disease. The scientist try to find probes that can make easier to

follow the mechanism of malformation of this fiber. The

important is to understand how this malformation cant influence in the

pathology.


may lead to disease

In the experiment the scientist fined some probes that permit identify the proteins and molecules that are involved in the process of the malformation of the fibronectin fiber. And with this understand better.


may lead to disease

With that probes they can not only see how do the deformation take place, they can regulate this, with signalization, and control de express of the sites that are involved in the deformation.


may lead to disease

MEDICAL APLICATION

Bio molecular tastes and techniques have a very important application to medicine. These applications are focus to different objective, but all of them are do it to find the welfare of the patient.

MEDICAL APLICATION

Is very interest to find the better treatment of a patient that has a specific pathology. This method improves the singular treatment and the survival patient prognosis.

MEDICAL APLICATION

See how the pathology develop in the patients with the particular characteristic of them, we can make a more central treatment and maybe be more effective to bite the disease. With these improving the medical execution.

MEDICAL APLICATION

Diagnostic pathology before express the real disease. This objective would represent a very important form to know how to proceed with a patient that is in risk

BIBLIOGRAPHY

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improved diagnostic test benefits children with acute myeloid

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