in vivo kinematics of anterior cruciate ligament...

1
Background Rotatory instability after ACL reconstruction (ACLR) can impair clinical outcomes 1,2 . The anterolateral complex provides rotary stability, and extra articular surgery in combination with ACLR has been proposed 3,4 . However, the extra articular surgery may over-constrain the knee joint 5 and induce lateral compartment osteoarthritis 6 . Adding this surgery remains controversial. Aim To compare tibiofemoral kinematics after ACLR alone versus ACLR plus lateral extra articular tenodesis (ACLR+LET) during dynamic activities. Hypothesis The side-to-side-difference (SSD) of tibial rotation and anterior translation relative to the femur will be less after ACLR+LET in comparison to ACLR-alone. In Vivo Kinematics of Anterior Cruciate Ligament Reconstruction with Lateral Extra Articular Tenodesis During Downhill Running Daisuke Chiba, Felipe Suntaxi, Bryson Lesniak, Andrew Sheean, Robert Tisherman, Freddie H. Fu, William Anderst, Volker Musahl Biodynamics Lab, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA Biodynamics Lab website: bdl.pitt.edu Introduction Methods Results Discussion References The SSD in ATT was greater in ACLR+LET patients compared with ACLR patients. This difference was significant at 0% of the gait cycle (p = 0.029, Figure 2A). No differences in TR were found between ACLR and ACLR+LET (Figure 2B). SSD in ATT and TR did not change over the first 40% of gait cycle. Main Finding ACLR+LET reduced the ATT, compared with ACLR, only at foot strike. The SDD of 3 to 4 mm in ATT was not statistically significant, but potentially clinically significant. This finding agrees with a previous in vivo study which showed LET reduced antero- posterior tibial translation 9 . On the contrary, our result disagrees with a previous cadaveric study which showed LET was not associated with the ATT 5 , and a clinical study using Lachman test that showed LET restored normal ATT 10 . Strength of the Study: This randomized study measured in vivo knee kinematics during a dynamic functional activity. Limitations: The relatively small sample size and evaluation at only 6-months post- surgery. These will be addressed by testing the remainder of the enrolled patients at 6-months post-surgery and all patients at 1-year follow-up. Clinical Significance At six months post-surgery, concomitant extra articular surgery with ACLR appears to restrict the anterior tibial translation in comparison to ACLR. Decreased anterior tibial translation after LET may affect graft healing during early rehabilitation. 1. Kocher et al., AJSM, 2004. 2. Tanaka et al., KSSTA, 2012. 3. Sonnery- Cottet et al., AJSM, 2015. 4. Zaffagnini et al., AJSM, 2017. 5. Geeslin et al., AJSM, 2018. 6. O’Brien et al., AJSM, 1991. 7. Anderst et al., Med Eng Phys., 2009. 8. Grood et al., J Biomech Eng., 1983. 9. Bignozzi et al., KSSTA, 2009. 10. Sonnery-Cottet et al., KSSTA, 2018. Subjects: 20 patients provided informed consent in this IRB-approved study and were randomized during surgery to receive ACLR or ACLR+LET. 10 patients (5 subjects in each group) have completed 6-month post-surgical kinematic testing (average age: 20.5 ± 7.4 years, 4F/6M). Kinematics of contralateral unaffected knee served as the control. Inclusion: a quantitative pivot-shift > 6 mm lateral translation or > 10 m/sec 2 tibial acceleration. Surgery: ACLR: anatomical single bundle; LET: Modified Lamaire’s technique. Data Collection Data Analysis The primary outcome variables were anterior tibial translation (ATT) and tibial rotation (TR) over the initial 40% of gait cycle. Non-paired t-test compared the SSD of kinematic values between ACLR and ACLR+LET at each 10% of the gait cycle. Changes in the SSD among each 10% gait cycle were identified by using repeated measured ANOVA (post-hoc test: Tukey test). P-value ≤ 0.05 was defined as statistically significant. Figure 1: (A) Participants performed three trials of downhill running (self-selected speed; average 2.0 m/s) on an instrumented treadmill while (B) synchronized biplane radiographs were collected at 150 images/s over the first 40% of the gait cycle. (C) Bilateral knee CT scans were collected and used to create 3D bone models. (D) Patient specific 3D bone models were created. (E) 3D knee kinematics were determined using a validated CT model-based tracking process 7 . (F) Knee translations were calculated from femur origin to tibia origin and knee rotations were calculated using standard methods 8 . A B C D E F Digitally Reconstructed Radiograph #2 Digitally Reconstructed Radiograph #1 Simulated X-ray Source #1 Simulated X-ray Source #2 3D Bone Model Figure 2. SSD in ATT (Figure 2A) and TR (Figure 2B). *: p-value ≤ 0.05 between ACLR and ACLR+LET. Error bar indicates ±1 Standard Deviation

Upload: others

Post on 08-Aug-2020

4 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: In Vivo Kinematics of Anterior Cruciate Ligament ...bdl.pitt.edu/wp-content/uploads/2019/01/ACLEAT_Chiba.pdf · Background • Rotatory instability after ACL reconstruction (ACLR)

Background• Rotatory instability after ACL reconstruction (ACLR) can impair clinical outcomes1,2. • The anterolateral complex provides rotary stability, and extra articular surgery in

combination with ACLR has been proposed3,4.• However, the extra articular surgery may over-constrain the knee joint5 and induce

lateral compartment osteoarthritis6. Adding this surgery remains controversial.Aim• To compare tibiofemoral kinematics after ACLR alone versus ACLR plus lateral

extra articular tenodesis (ACLR+LET) during dynamic activities.Hypothesis• The side-to-side-difference (SSD) of tibial rotation and anterior translation relative to

the femur will be less after ACLR+LET in comparison to ACLR-alone.

In Vivo Kinematics of Anterior Cruciate Ligament Reconstruction with Lateral Extra Articular Tenodesis During Downhill Running

Daisuke Chiba, Felipe Suntaxi, Bryson Lesniak, Andrew Sheean, Robert Tisherman, Freddie H. Fu, William Anderst, Volker MusahlBiodynamics Lab, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA

Biodynamics Lab website: bdl.pitt.edu

Introduction

Methods

Results

Discussion

References

• The SSD in ATT was greater in ACLR+LET patients compared with ACLR patients. This difference was significant at 0% of the gait cycle (p = 0.029, Figure 2A).

• No differences in TR were found between ACLR and ACLR+LET (Figure 2B).• SSD in ATT and TR did not change over the first 40% of gait cycle.

Main Finding• ACLR+LET reduced the ATT, compared with ACLR, only at foot strike.

• The SDD of 3 to 4 mm in ATT was not statistically significant, but potentially clinically significant.

• This finding agrees with a previous in vivo study which showed LET reduced antero-posterior tibial translation9.

• On the contrary, our result disagrees with a previous cadaveric study which showed LET was not associated with the ATT5, and a clinical study using Lachman test that showed LET restored normal ATT10.

• Strength of the Study: This randomized study measured in vivo knee kinematics during a dynamic functional activity.

• Limitations: The relatively small sample size and evaluation at only 6-months post-surgery. These will be addressed by testing the remainder of the enrolled patients at 6-months post-surgery and all patients at 1-year follow-up.

Clinical Significance• At six months post-surgery, concomitant extra articular surgery with ACLR

appears to restrict the anterior tibial translation in comparison to ACLR. • Decreased anterior tibial translation after LET may affect graft healing during

early rehabilitation.

1. Kocher et al., AJSM, 2004. 2. Tanaka et al., KSSTA, 2012. 3. Sonnery-Cottet et al., AJSM, 2015. 4. Zaffagnini et al., AJSM, 2017. 5. Geeslin et al., AJSM, 2018. 6. O’Brien et al., AJSM, 1991. 7. Anderst et al., Med EngPhys., 2009. 8. Grood et al., J Biomech Eng., 1983. 9. Bignozzi et al., KSSTA, 2009. 10. Sonnery-Cottet et al., KSSTA, 2018.

Subjects: 20 patients provided informed consent in this IRB-approved study and were randomized during surgery to receive ACLR or ACLR+LET.• 10 patients (5 subjects in each group) have completed 6-month post-surgical

kinematic testing (average age: 20.5 ± 7.4 years, 4F/6M). • Kinematics of contralateral unaffected knee served as the control.• Inclusion: a quantitative pivot-shift > 6 mm lateral translation or > 10 m/sec2 tibial

acceleration.• Surgery: ACLR: anatomical single bundle; LET: Modified Lamaire’s technique.

Data Collection

Data Analysis• The primary outcome variables were anterior tibial translation (ATT) and tibial

rotation (TR) over the initial 40% of gait cycle. • Non-paired t-test compared the SSD of kinematic values between ACLR and

ACLR+LET at each 10% of the gait cycle. • Changes in the SSD among each 10% gait cycle were identified by using repeated

measured ANOVA (post-hoc test: Tukey test).• P-value ≤ 0.05 was defined as statistically significant.

Figure 1: (A) Participants performed three trials of downhill running (self-selected speed; average 2.0 m/s) on an instrumented treadmill while (B) synchronized biplane radiographs were collected at 150 images/s over the first 40% of the gait cycle. (C) Bilateral knee CT scans were collected and used to create 3D bone models. (D) Patient specific 3D bone models were created. (E) 3D knee kinematics were determined using a validated CT model-based tracking process7. (F) Knee translations were calculated from femur origin to tibia origin and knee rotations were calculated using standard methods8.

A B

C D

E

F

Digitally Reconstructed Radiograph #2

Digitally Reconstructed Radiograph #1

Simulated X-raySource #1

Simulated X-raySource #2

3D Bone Model

Figure 2. SSD in ATT (Figure 2A) and TR (Figure 2B). *: p-value ≤ 0.05 between ACLR and ACLR+LET. Error bar indicates ± 1 Standard Deviation