EVERY URINARYCONDITION DESERVES TO BEDILUTEDTailored nutritional solutionsto support feline and canineurinary health

INCRED IBLE IN EVERY DETA IL

MAIN RISK FACTORS55-65%

IdiopathicCystitis

15-21% Urolithiasis

10-21% Urethral

plugs

1-2% Neoplasia

1-8% Infection

10% Anatomic

defects

9% Behaviour disorders

CAT

40% Cystitis (Urinary Tract

Infection included)

18% Others

18% Urolithiasis

24% Incontinence

DOG

LOWER URINARY TRACT DISEASE:

ONE DISEASE –MULTIPLECONDITIONSLower urinary tract disease (LUTD) encompasses a varietyof conditions that affect the bladder and urethra. That’swhy, despite significant advances in veterinary medicine andthe latest diagnostic technologies, LUTD remains challenging to manage.

MOSTCOMMONLUTD

CLINICAL SIGNS

RECURRENCE IS COMMON

Source: Lulich JP, Osborne CA, Bartges JW et al - Canine lowerurinary tract disorders. In Ettinger SJ, Feldman EC, (eds). Textbook ofVeterinary Internal Medicine Diseases of the Dog and Cat. 5th edition.Philadelphia: WB Saunders Co, 2000: 1747-1781.

1 Chew D – Canine and Feline Nephrology and Urology; p 336; Elsevier 2011.2 Bartges J & Polzin DJ – Nephrology and Urology of Small Animals. Wiley-Blackwell 2011.

Source: Susan Little, The Cat: Clinical Medicineand Management. Elsevier 2012. ISBN: 978-1-4377-0660-4 page 981.

Periuria(urinating ininappropriateplaces)

Anuresis(unable topass urine)

Dysuria(painfulurination)

Haematuria(blood in urine)

Stranguria(straining whileurinating)

In cats, Feline IdiopathicCystitis (FIC) is a chronicdisease with frequent

relapses.

Pollakiuria(increasedfrequency ofurination)

50%of cats with FIC can haveanother episode within

12 months1.

Urolithiasis can recur if the risk factors do not change(diet, lifestyle, infection,

weight, etc.).

same circumstances =

same consequences2

In dogs, where UrinaryTract Infections are themost common LUTD,

5%of positive culturesare from recurrent

infections1.

Stress

Overweight or obesity

Insufficient water intake

Inadequate diet

Existing disease

Medical treatment

Age

Breed

Gender

URINARYSIGNS

High quality proteins

Controlled and balanced mineral

content

ROYAL CANIN RSS PERFORMANCE

02FOOD

3Landsberg G, Milgram B, Mougeot I - Therapeutic effects of an alphacasozepine and L-tryptophan supplemented diet on fear and anxiety in the cat. *National Research Council, Nutrient requirements of dogs and cats, 2006.

01

WET OR SPECIFIC DRY FORMULA COULD INCREASE WATER INTAKE

ml/kg*Daily water requirement

DOGml/kg*

CAT

Daily water requirement

METASTABLE SUPERSATURATIONCrystal solubility

No crystal formation/dissolution

LABILE SUPERSATURATIONCrystal formation

UNDERSATURATION

WET ORI

mCATAT

Daily water re

WHATEVER THE CONDITION,

NUTRITION PLAYSA KEY ROLE TOHELP SUPPORT APET WITH LUTDControlling water, nutrient and mineral intake can play a key role in supporting a urinary patient’s recovery.

HYDRATIONINCREASING WATERINTAKE TO DILUTE URINE

LUTD CAN BEDIET-RESPONSIVE3

WET DIETS OR A SPECIFIC DRY FORMULATIONCAN INCREASE WATER INTAKE

• Nutritional management plays aprimary role in the dissolution ofstruvite uroliths.

• Low calcium oxalate (CaOx) RSS willreduce the formation of CaOx crystals.

• Specific nutrients are useful in themanagement of cats with FIC.

High quality proteins

Controlled and balanced mineral

content

No crystal f

ROYAL CANIN® DIETSincrease water intakeand guarantee high

Relative Supersaturation (RSS)performance in mixed feeding

Specific nutrientslike L-tryptophan

or alpha-casozepine

FELINE NUTRITIONAL MANAGEMENT

DECISION TREECANINE NUTRITIONAL MANAGEMENT

DECISION TREEDISSOLUTION OF PURE STRUVITE CRYSTALS/STONES AND REDUCTION OF FORMATION OF CALCIUM OXALATE

OR STRUVITE CRYSTALS/STONES

LONG TERMMANAGEMENT

OF CATS WITH FIC

IDEALWEIGHT

IDEALWEIGHT

NEUTERED OR PRONE TOWEIGHT GAIN

NUTRIENT INTOLERANCE

IDEALWEIGHT

NEUTERED OR PRONE TOWEIGHT GAIN

NUTRIENT INTOLERANCE

OVERWEIGHT/OBESE(BCS=6)

P

>

AGE

S

I

P

H

CAT D

i

DOG

URINARY

HYPOALLERGENIC

URINARY

SATIETY

URINARY

CALM

URINARY S/O URINARY S/O URINARY S/O URINARY S/O URINARY URINARY S/OMODERATE CALORIE

URINARY S/OMODERATE CALORIE

SINGLECONDITION

MULTIPLECONDITIONS

MULTIPLECONDITIONS

SINGLECONDITION

DISSOLUTION OF PURE STRUVITE CRYSTALS/STONES AND REDUCTION OF FORMATION OF CALCIUM OXALATE

OR STRUVITE CRYSTALS/STONES

REDUCTION OFFORMATION OFURATE CYSTINE OR XANTHINE

CRYSTALS/STONES

sSMALL DOGS

U/CAGEING 7+

< 7 YEARS OLD > 7 YEARS OLD

< 10kg Body Weight > 10kg Body Weight

OVERWEIGHT/OBESE(BCS=6)>

+ + URINARY

HYPOALLERGENIC

URINARY

SATIETY+ ++

WHAT IT IS

WHEN TO USE IT

PROBLEMOR RISK

AT HOME HEMATURIA DETECTION

TEST

DIAGNOSIS

W

W

W

W

W

LITTER GRANULES FOR BETTER FOLLOW UP

RECURRENCE IS COMMON

Early detection of signs of recurrence can reduce complications

• White granules with a reagent incorporated that turns fromwhite to blue when it comes intocontact with blood.

HEMATURIA DETECTION should be used as a followup after an episode of LUTD.

VETERINARYRECOMMENDATION• Medication• Adapted

nutrition• HEMATURIA

DETECTION

IF GRANULESTURN BLUE,CONSULT YOUR VETFOLLOW UP

CAT OWNERS WORRY ABOUT THEIR PET’S HEALTH

Difficult to have effective follow up at home

CATS OFTEN HIDE SIGNS OF DISEASE

Difficult to detect healthproblems at an early stage

HEMATURIA IS A STRONG INDICATOROF MOST LUTD

Early detection of this key indicator can enable earlier intervention

ROYAL CANIN HEMATURIA DETECTION BY BLÜCARE IS A TOOL WHICH ENABLES

EARLY DETECTION OF BLOOD IN A CAT’S URINE MAKING HEALTH

MANAGEMENT EASIER

A BREAKTHROUGHTOOL FOR

HAEMATURIA DETECTION

LUTD SIGNS ARECHALLENGINGTO FOLLOW

Spread the granulesover the cat litter.

Inspect the litter boxafter the cat urinates.

If the granules arewhite, the test is negative.

If the granules haveturned blue,the testis positive and indicatesthe presence of bloodin the cat’s urine.

Consult your vetwithout delay.

HOW TO USE IT

SYSTEM

SYSTEM

SYSTEM

MAIN FEATURES AND BENEFITS

URINARY TRACT HEALTH

COGNITION AND VITALITY

AGEING SUPPORT

HIGHLY PALATABLE PRODUCTS

URINARY SECURITY

Effective struvite stonedissolution and specificallyformulated for up to 80%

of all urinary stones.

Support dogs’ vitality and cognition with an exclusive

blend of nutrients and antioxidants. Also supports

kidney health.

To facilitate food intake with ageing dogs suffering

from poor appetite.

RSS tested to reduce the risk of struvite and calcium oxalate

crystal formation.

SYSTEM

DRY1kg / 3.5kg / 8kg

WETPOUCH 85g

COMPLIANT MIXED FEEDING COMBINATION

NEW PRODUCT INNOVATION

URINARY S/O AGEING 7+Cutting edge innovation to effectively manage and support ageing dogs with LUTD.

MORE THAN 1/5DOGS DEVELOP COGNITIVE DYSFUNCTION

SYNDROME AFTER 9 YEARS OLD

OTHER ISSUES EFFECTING AGEING DOGS INCLUDE:

Increased susceptibility to infection

Decreased capacity to retain water

Behavioural changes

Increased sensitivity to stimuli

Sarcopenia

Poor appetite

Reduced nutrient absorption

LOWER URINARY TRACT DISEASE:

ONE GOAL

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4 Buffington CA et al -Clinical evaluation of multimodal environmental modification (MEMO) in the management of cats with idiopathic cystitis. J Feline Med Surg. 2006 Aug;8(4):261-8.

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0102

Over the years, we have continued towards a common goal of ensuring the best urinaryhealth for pets. As your nutritional partner, we are determined to go further in oursearch for more innovative nutritional solutions and services to ensure your clients aremore satisfied and your business more successful.

Together, we can support your patients to help maintain their urinary health.

• History • Clinical examination• Radiography • Urinalysis• Ultrasonography

• Increase water intake• Diet adaptation• Medical treatment• Environmental modification(FIC cats)

• Lifestyle changes• Surgery

• Regular urinalysis• Specific diet• Weight monitoring (in petsat risk of obesity)

• Environmental changes incats (identify triggeringfactors)4

• Hematuria Detection

• To build awareness and knowledge

• To ensure long termcompliance

• To minimise concern• To help avoidrecurrence

DIAGNOSIS

MANAGEMENT PROTOCOL

FOLLOW UP

TO MINIMISE RECURRENCE

PET OWNER

COMMUNICATION

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