institute of cancer research - institut du cancer icr’s activities in cancer imaging

Institute of Cancer Research - Institut du cancer

ICR’s Activities in ICR’s Activities in Cancer ImagingCancer Imaging


Funding Sources for Imaging Research in Funding Sources for Imaging Research in CanadaCanada

Federal• Canadian Institutes of Health Research (CIHR)• Natural Science and Engineering Research Council (NSERC)• Canadian Foundation for Innovation (CFI)• National Research Council (NRC)• Natural Resources Canada (NRCan)

• Canada Research Chairs (CRC)• Canada Excellence Research Chairs (CERC)• Networks of Centres of Excellence (NCE)• Centres of Excellence for Commercialization and Research(CECR)

Other• Cancer – Canadian Cancer Research Alliance (CCRA)

Provinces (Alberta Innovates, OICR); NGOs (CCS, TFRI)

CIHRCIHR

Created in 2000 to replace the Medical Research Council CIHR is Canada’s federal funding agency for health research CIHR’s mission is to create new scientific knowledge and to enable its

translation into improved health, more effective health services and products, and a strengthened Canadian health care system.

CIHR supports more than 13,200 health researchers and trainees across Canada

CIHR funds both investigator-initiated research as well as research on targeted priority areas

CIHR builds research capacity in under-developed areas and training the next generation of health researchers

CIHR focuses on knowledge translation that facilitates the application of the results of research and their transformation into new policies, practices, procedures, products and services

CIHR operates with a $1 billion annual budget CIHR has 13 virtual Institutes



Canadian Institutes of Health Research Canadian Institutes of Health Research (CIHR)(CIHR)

In the beginning ………In the beginning ………



Bringing a community together

Outcomes of the first workshopOutcomes of the first workshop

• Brought the oncology, cardiology and neurology imaging communities together

• Provided a series of recommendation for addressing the challenges in imaging

• Led to $10M, in Budget 2010, to support the first national imaging clinical trials network – MITNEC

• MITNEC now coordinating clinical trials on the new products produced in the Isotope initiative



Making International Connections

Imaging Workshop – Canada/US/UKImaging Workshop – Canada/US/UKLinking ‘omics to Patient care Through ImagingLinking ‘omics to Patient care Through Imaging

The workshop was jointly organized by CIHR-ICR, NCI and CRUK and hosted by the Canadian High Commission in London, UK

The event brought together leading academic imaging and molecular science researchers from Canada (9); the UK (12); and the US (10), as well as organizing committee members, program staff and representatives of other UK research agencies

The goal of the workshop was to assess the feasibility of combining imaging expertise, resources and infrastructures among the three countries

The workshop included keynote presentations (two from each country); short presentations from participating researchers; a series of three breakout sessions; and informal networking opportunities

Discussions focused on finding common solutions to the existing barriers to translational research in cancer imaging


Key Recommendations from the Key Recommendations from the Canada/US/UK WorkshopCanada/US/UK Workshop

The workshop generated great enthusiasm for the development of

Canada/UK/US collaborations that could address an identified need to:

Optimize and validate innovative imaging platforms and methods that meet the

sensitivity and specificity performance requirements for specific cancer problems

Provide robust quantitative measurements (as opposed to traditional qualitative methods), and optimize these methods for more efficient large-scale metadata analysis, and correlation with other research domains such as genomics, epigenetics, proteomics and other laboratory biomarker measurements.

Promote Interdisciplinary research in imaging and molecular sciences so more effective molecular or mechanistic-based solutions for data integration across the three imaging research domains can be explored and shared both nationally and internationally.


Development of a Management Development of a Management PlanPlan

Funding Opportunity: Quantitative Imaging for Prediction and/or Evaluation of Responses to Cancer Therapies

The six-page Management Plan covered: Goals of the program – establish two Canadian teams as an integral part of QIN

Program delivery model – submit directly to NIH

Funding opportunity announcement – CIHR website, NIH Guide for Grants and Contracts

Relevance review – NCI program staff, CIHR for eligibility check of applicant

Review of full applications – NIH and NCI policies and procedures, CIHR observer

QIN executive committee – CIHR representative on QIN Executive Committee

Communications – NCI and CIHR, French and English, for CIHR formal news releases through Canadian Minster of Health

Ownership of IP - awardees

Access to Information and privacy act - according to national regulations

Termination – provide notice in writing, meet to discuss future of program

Dispute resolution - resolved jointly by NCI and CIHR

Agreement non-legally binding Collaboration Contact information


Funding Opportunity: Funding Opportunity: Quantitative Imaging for Quantitative Imaging for Prediction and/or Evaluation of Responses to Prediction and/or Evaluation of Responses to

Cancer TherapiesCancer Therapies

September 2013 - Alert imaging research community to the upcoming call

October 2013 – Post funding opportunity on CIHR website with links to the NIH websites

November 2013 – Webinex for interested researchers Applications due February 2014 ICR, in partnership with Genome BC, will provide funding to

support up to two Canadian QIN nodes for five years Investment will be up to $400,000 per node per annum – this

aligns well with the funding for the US nodes Program will be run by the NIH through their regular processes. The top two fundable Canadian applications will be funded


Canadian Participation in Canadian Participation in QINQIN

As permitted under existing laws, regulations and policies

the Canadian teams will participate in and contribute to:

QIN research activities collaborative working groups consensus publications monthly teleconferences annual and semi-annual meetings other participatory activities of the Network


Going Forward



We’re growing!

institute of cancer research - institut du cancer icr’s activities in cancer imaging

Documents

imaging research

cancer slide

cancer imaging slide

research capacity

translational research

results of research

medical research council

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