intussusception of the large colon in a horse

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similarities and disparities of this condition to achaIasia of man and megaesophagus of dogs are discussed. Gastroesophageal Ulceration and Candidiasis in Foals. Gross, Thelma L. and Mayhew, fan G. JA VMA, Vol. 182, No. 12, (1983): 1370-1373. Gastroesophageal candidiasis was associated with ulceration in 5 foals and was characterized clinically by signs of severe abdominal pain and occult blood in gastric fluid and feces. Clinical demonstration of Candida was by bytology and culture of gastric fluid or by gastroscopy and biopsy. Candida was confirmed by cytology and culture of gastric fluid or by gastroscopy and biopsy. Candida colonized the hyperkeratotic mucosa surrounding the ulcers, and the associated suppurative inflammation resulted in splitting of the mucosal epithelium. Loss of the protective superficial mucosa may have allowed invasion by bacteria leading to ulceration. Persistent Cloaca and Atresia in a Foal. W.S. Furie. Equine Practice, Vol. 5, No. 1, (1983): 30-33. A full-term Thoroughbred filly with no external anal opening and no apparent rectum was eulhanized. Autopsy results are presented. Development of the human fetal hindgut is discussed and illustrated by a line drawing. Extrapolation of data from human studies is made. Color plates are included. CongenRal Intestinal Agangtionosis in White Foals, Vonderfecht, S.L., Trommershausen Bowling, A. and Cohen, M. Vet. Pathol., 20, (1983): 65-70. A congenital and probably hereditary neurological defect has been identified in the intestinal tract of six foals produced from the breeding of overo (a type of spotting pattern) horses. The foals had white hair and pink skin with the exception of occasional pigmented foci about the muzzle, ventral abdomen, and hindquarters. The foals appeared normal at birth, but within a few hours developed symptoms of colic. At necropsy, the only significant finding was a narrow, pale segment of large intestine. This abnormality either was confined to the small colon and rectum or involved the entire colon and rectum. Microscopically, myenteric and submucosal neuronal plexuses were absent throughout the large intestine and extensive portions of the small intestine The only other significant finding was the lack of melanin in the skin. Right Dorsal Displacement of the Large Colon in the Horse, Huskamp, B. and Kapt, N. Equine Practice, Vol. 5, No. I, (I983): 20-29. The condition defined as right dorsal displacement of the large colon is described. Line drawings illustrating the normal position of the large colon and right dorsal displacement are included. The history and physical and clinical findings of cases presented in the author's practice are given. A rectal examination as a diagnostic aid is described. Treatment regimens are described in 48 cases. The etiology of the condition as described in the author's experience is discussed. Intussusception of the Large Colon in a Horse, Dyson, Sue and Orsini, James. JAVMA, Vol. 182, No. 7, (1983): 720. This case report describes a horse that was presented with the chief complaint of an acute abdomen. The actual presenting signs were of such a nature that medical therapy was instituted with reevaluation during the subsequent 12 hours. The filly continued to have signs ol mild abdominal discomfort with Volume 4, Number 1 taehyeardia. Subsequent abdominoparacentesis and rectM examination revealed changes which indicated a surgical problem to be present. Exploratory celiotomy was performed which revealed a colonic intussusception of the pelvic flexure. Resection of this portion of the colon was not required. The patient recovered uneventfully postoperatively, There is presently only one report of such a problem in the literature, with an additional one noted by personal communication. Jejunal Intussusception Associated with Leiomyoma in an Aged Horse. Collier, Michael A. and Trent, Ava M. JA VMA, Vol. 182, No. 8, (1983): 819-821. Jejunal intussusception associated with an intramural mass was diagnosed in an aged horse, based on the results of physical, laboratory, and surgical examinations. The intramural mass was diagnosed histologically as a leiomyoma. Approximately 10 m of jejunum was resected successfully. Following surgery, D-xylose absorption was reduced but absorption at 90 days was a, dequate. The ease of postoperative nutritional adaptation in this case was attributable to the preservation of the ileum at surgery. Leiomyoma of the Small Intestine in a Horse. Hanes, Gary E. and Robertson, James T. JA VMA, Vol. 182, No. 12, (1983): 1398. A leiomyoma of the wall of the jejunum was diagnosed at postmortem examination of an I I-year-old Morgan gelding. Although this neoplasm resulted in intestinal obstruction and secondary gastric rupture, the focal nature of the mass suggests the possibility of surgical resection and intestinal anastomosis. Although rare, tumors of this nature should be included in the differential diagnosis of obstructive bowl disease. Isolation of Virus and Antibody Containing Immune Complexes from Mink with Aleutian Disease by Affinity Chromatography of Equine Complement Clq. Burger, D., Sriranganathan, N., McDonald, T.L_ and Gorham, J.R. Am. J. Vet Res., 44, (1983):86. Affinity chromatography on immobilized equine complement Clq was used for the isolation of complement- binding immune complexes in sera of mink infected with Aleutian disease virus. Immune complexes were isolated and quantitated from four of five infected mink, as early as two weeks after infection and before hypergammaglobulinemiahad appeared. The quantity ofimmunoglobulin G in these immune complexes ranged from 180 to 370 ug/ml serum. There were no Clq-binding immune complexes found in mink which were negative for Aleutian disease antibody. Using tz~i-labeled BSA- anti-BSA complexes, we demonstrated that the affinity columns bound selectively immune complexes which had formed in antibody excess, whereas immune complexes in antigen excess were not hound. By neutralization of sensitized virus with anti-mink IgG serum, non-Clq-binding immune complexes were also detected, which indicates circulating immune complexes in persistently infected mink are heterogeneous as far as their reactivity with equine Clq is concerned. 41

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Page 1: Intussusception of the large colon in a horse

similarities and disparities of this condition to achaIasia of man and megaesophagus of dogs are discussed.

Gastroesophageal Ulceration and Candidiasis in Foals. Gross, Thelma L. and Mayhew, fan G. JA VMA, Vol. 182, No. 12, (1983): 1370-1373.

Gastroesophageal candidiasis was associated with ulceration in 5 foals and was characterized clinically by signs of severe abdominal pain and occult blood in gastric fluid and feces. Clinical demonstration of Candida was by bytology and culture of gastric fluid or by gastroscopy and biopsy. Candida was confirmed by cytology and culture of gastric fluid or by gastroscopy and biopsy. Candida colonized the hyperkeratotic mucosa surrounding the ulcers, and the associated suppurative inflammation resulted in splitting of the mucosal epithelium. Loss of the protective superficial mucosa may have allowed invasion by bacteria leading to ulceration.

Persistent Cloaca and Atresia in a Foal. W.S. Furie. Equine Practice, Vol. 5, No. 1, (1983): 30-33.

A full-term Thoroughbred filly with no external anal opening and no apparent rectum was eulhanized. Autopsy results are presented. Development of the human fetal hindgut is discussed and illustrated by a line drawing. Extrapolation of data from human studies is made. Color plates are included.

CongenRal Intestinal Agangtionosis in White Foals, Vonderfecht, S.L., Trommershausen Bowling, A. and Cohen, M. Vet. Pathol., 20, (1983): 65-70.

A congenital and probably hereditary neurological defect has been identified in the intestinal tract of six foals produced from the breeding of overo (a type of spotting pattern) horses. The foals had white hair and pink skin with the exception of occasional pigmented foci about the muzzle, ventral abdomen, and hindquarters. The foals appeared normal at birth, but within a few hours developed symptoms of colic. At necropsy, the only significant finding was a narrow, pale segment of large intestine. This abnormality either was confined to the small colon and rectum or involved the entire colon and rectum. Microscopically, myenteric and submucosal neuronal plexuses were absent throughout the large intestine and extensive portions of the small intestine The only other significant finding was the lack of melanin in the skin.

Right Dorsal Displacement of the Large Colon in the Horse, Huskamp, B. and Kapt, N. Equine Practice, Vol. 5, No. I, (I983): 20-29.

The condition defined as right dorsal displacement of the large colon is described. Line drawings illustrating the normal position of the large colon and right dorsal displacement are included. The history and physical and clinical findings of cases presented in the author's practice are given. A rectal examination as a diagnostic aid is described. Treatment regimens are described in 48 cases. The etiology of the condition as described in the author's experience is discussed.

Intussusception of the Large Colon in a Horse, Dyson, Sue and Orsini, James. JAVMA, Vol. 182, No. 7, (1983): 720.

This case report describes a horse that was presented with the chief complaint of an acute abdomen. The actual presenting signs were of such a nature that medical therapy was instituted with reevaluation during the subsequent 12 hours. The filly continued to have signs ol mild abdominal discomfort with Volume 4, Number 1

taehyeardia. Subsequent abdominoparacentesis and rectM examination revealed changes which indicated a surgical problem to be present. Exploratory celiotomy was performed which revealed a colonic intussusception of the pelvic flexure. Resection of this portion of the colon was not required. The patient recovered uneventfully postoperatively,

There is presently only one report of such a problem in the l i terature, with an addi t iona l one noted by personal communication.

Jejunal Intussusception Associated with Leiomyoma in an Aged Horse. Collier, Michael A. and Trent, Ava M. JA VMA, Vol. 182, No. 8, (1983): 819-821.

Jejunal intussusception associated with an intramural mass was diagnosed in an aged horse, based on the results of physical, laboratory, and surgical examinations. The intramural mass was diagnosed histologically as a leiomyoma. Approximately 10 m of jejunum was resected successfully. Following surgery, D-xylose absorption was reduced but absorption at 90 days was a, dequate. The ease of postoperative nutritional adaptation in this case was attributable to the preservation of the ileum at surgery.

Leiomyoma of the Small Intestine in a Horse. Hanes, Gary E. and Robertson, James T. JA VMA, Vol. 182, No. 12, (1983): 1398.

A leiomyoma of the wall of the jejunum was diagnosed at postmortem examination of an I I-year-old Morgan gelding. Although this neoplasm resulted in intestinal obstruction and secondary gastric rupture, the focal nature of the mass suggests the possibility of surgical resection and intestinal anastomosis. Although rare, tumors of this nature should be included in the differential diagnosis of obstructive bowl disease.

Isolation of Virus and Antibody Containing Immune Complexes from Mink with Aleutian Disease by Affinity Chromatography of Equine Complement Clq. Burger, D., Sriranganathan, N., McDonald, T.L_ and Gorham, J.R. Am. J. Vet Res., 44, (1983):86.

Aff in i ty c h r o m a t o g r a p h y on immobi l i zed equ ine complement Clq was used for the isolation of complement- binding immune complexes in sera of mink infected with Aleutian disease virus. Immune complexes were isolated and quantitated from four of five infected mink, as early as two weeks after infection and before hypergammaglobulinemia had appeared. The quantity ofimmunoglobulin G in these immune complexes ranged from 180 to 370 ug/ml serum. There were no Clq-binding immune complexes found in mink which were negative for Aleutian disease antibody. Using tz~i-labeled BSA- anti-BSA complexes, we demonstrated that the affinity columns bound selectively immune complexes which had formed in antibody excess, whereas immune complexes in antigen excess were not hound. By neutralization of sensitized virus with anti-mink IgG serum, non-Clq-binding immune complexes were also detected, which indicates circulating immune complexes in persistently infected mink are heterogeneous as far as their reactivity with equine Clq is concerned.

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