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BIBLIOGRAPHY Abbott, P.J. (1986). Caffeine: a toxicological review. Med. J. Aust. 145: 518-521. Abraham, S., Faulkin, L.J., Hillyard, L.A. and Mitchell, D.J. (1984). Effect of dietary fat on tumorigenesis in the mouse mammary gland. J. Natl. Cancer Inst. 72: 1421-1429. Afanas'ev, Y.J. and Israfilova, R. Sh. (198ij). Changes in histochemical and morphometric parameters of the mouse mammary gland in response to different doses of vitamin A. Bull. Exp. Biol. Med-Engl (Tr) 96: 1774- 1778. Anderson, R.R. (1974). Development and structure of the mammary gland. In: B.L. Larson and V.R. Smith (eds), Endocrinological control of lactation: A comprehensive treatise, Vol .. I. Academic Press, New York, pp. 97-140. Anderson, R.R. (1976). Relation between mammary gland develop- ment and body weight. J. Dairy Sci. 59: 1518-1521. Anderson, R.R. (1978). Embryonic and fetal development of the mammary apparatus. In: B.L. Larson (ed), Lactation: A comprehensive treatise, Vol. IV. Academic Press, New York, pp. 3-37. Aranda, J.V., Gorman, W., Loughnan, P.M. and Aldridge, A. (1978). Pharmacokinetic profile of caffeine in the premature infant with apnea. J. Pediat. 94: 663-668. * Arjungi, K.N. (1976). Areca Nut: A review. Arzneim. Forsch. 26: 951-956. M.J. (1984). Products of metabolism of caffeine. In: P.B. Dew (ed), Caffeine: perspectives from recent research. International Life Science Institute, Springer-Verlag, 3-38. Atal, C.K.(1980). In: Chemistry and pharmacology of vas1c1ne: A new oxytocic and abortifacient. _Rajbandhu Industrial Co., New Delhi;. Aylsworth, C.F., Jone, C., Trosko, J.E., Meites, J. and Welsch,· C.C. (1984). Promotion of 7,12-dimethylbenz [a)-anthracene-induced mammary tumorigenesis by high dietary fat in the rat. Possible role of intercellular communication. J. Natl. Cancer Inst. 72 637-647.

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Page 1: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

BIBLIOGRAPHY

Abbott, P.J. (1986). Caffeine: a toxicological review. Med. J. Aust. 145: 518-521.

Abraham, S., Faulkin, L.J., Hillyard, L.A. and Mitchell, D.J. (1984). Effect of dietary fat on tumorigenesis in the mouse mammary gland. J. Natl. Cancer Inst. 72: 1421-1429.

Afanas'ev, Y.J. and Israfilova, R. Sh. (198ij). Changes in histochemical and morphometric parameters of the mouse mammary gland in response to different doses of vitamin A. Bull. Exp. Biol. Med-Engl (Tr) 96: 1774-1778.

Anderson, R.R. (1974). Development and structure of the mammary gland. In: B.L. Larson and V.R. Smith (eds), Endocrinological control of lactation: A comprehensive treatise, Vol .. I. Academic Press, New York, pp. 97-140.

Anderson, R.R. (1976). Relation between mammary gland develop­ment and body weight. J. Dairy Sci. 59: 1518-1521.

Anderson, R.R. (1978). Embryonic and fetal development of the mammary apparatus. In: B.L. Larson (ed), Lactation: A comprehensive treatise, Vol. IV. Academic Press, New York, pp. 3-37.

Aranda, J.V., Gorman, W., Loughnan, P.M. and Aldridge, A. (1978). Pharmacokinetic profile of caffeine in the premature infant with apnea. J. Pediat. 94: 663-668.

* Arjungi, K.N. (1976). Areca Nut: A review. Arzneim. Forsch. 26: 951-956.

Arna~d, M.J. (1984). Products of metabolism of caffeine. In: P.B. Dew (ed), Caffeine: perspectives from recent research. International Life Science Institute, Berl~n. Springer-Verlag, 3-38.

Atal, C.K.(1980). In: Chemistry and pharmacology of vas1c1ne: A new oxytocic and abortifacient. _Rajbandhu Industrial Co., New Delhi;.

Aylsworth, C.F., Jone, C., Trosko, J.E., Meites, J. and Welsch,· C.C. (1984). Promotion of 7,12-dimethylbenz [a)-anthracene-induced mammary tumorigenesis by high dietary fat in the rat. Possible role of intercellular communication. J. Natl. Cancer Inst. 72 637-647.

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113

Aylsworth, C.F., Cullum, M.E., Zile, M.H. and Welsch, C.W. (1986). Influence of dietary retinyl acetate on normal rat mammary gland development and on the enhancement of 1,12-Dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by high levels of dietary fat. J. Natl. Cancer Inst. 76: 339-345.

Balinsky, B.I. (1950). On the prenatal growth of the mammary gland in the mouse. J. Anat. 84: 227-235.

Banerjee, M.R. (1976). Response of mammary cells to hormones. Int. Rev. Cyt, 47: 1-84.

Banerjee, M.R. and Banerjee, D.N. (1971). Hormonal regulation of RNA synthesis and membrane ultra-structure in mouse mammary gland. Exp. Cell Res. 64: 307-316.

Banerjee, M.R. and Rogers, F.M. (1971). Stimulation of the synthesis of macromolecules by ovarian hormones during early development of the mouse mammary gland. J. Endocrinol. 49: 39-49.

Banerjee, M.R. and Walker, R.J. (1967). Variable duration of DNA synthesis in mammary gland cells duri·ng pregnancy and lactation of C3H/He mouse. J. Cellular Physiol. 69: 133-142.

Banerjee, M.R., Wood, B.G., Lin, F.K. and Crump, L.R. (1976).

Bani,

Bani,

Organ culture of. whole mammary gland of tghe mouse. TCA Manual. 2: 457-462.

G.' Bigazzi, M. and Bani, D. (1985). Effects of relaxin on the mouse mammary gland I. The myoepi-thelial cells. J. Endocrinol. Invest. 8: 207-215.

G. ' Bigazzi, M. and Bani, D. (1986). The effects of relaxin on the mouse mammary gland II. The epithelium. J. Endocrinol. Invest. 9: 145-152.

Bartus, R.T., Dean, R.L. and Beer, B. (1980). Memory deficit in aged cebus monkeys and facilitation with central cholinomimetics. Neurobiol. Aging 1: 145-152.

Bassler, R. (1970). The structural changes Pathol. 53: 1-89.

morphology in female

of hormone induced breast. Curr. Top.

Bennet, D.C., Peachy, L.A., Durbin, H., Rudland, P.S. (1978). A possible mammary stem cell line. Cell 15: 283-298.

Benson, G.K., Folley, S.J. (1957). The effect of oxytocin on mammary gland involution in the rat. J. Endocrinol • .!..§.: 189-201.

Bhide, S.V., Gothoskar, S.V. and Shivapurkar, N.M. (1984). Arecoline tumorigenicity in Swiss strain mice on normal and vitamin B deficient diet. J. Cancer Res. Clin. Oncol,.',107: 169-171.

Page 3: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

114

Bhide, S. V., Shi.vapurkar, N .M., Gothoskar, S. V. and Ramadi ve, K.J.(1979). Carcinogenicity of betal quid ingredients: Feeding mice with aqueous extract and the polyphenol fraction of betel nut. Br. J. Cancer. 40: 922-926. --

Bachert, G., Rahm, U. and Schnieders, B. (1978). Pharmaco­kinetics of embryotoxic direct-acting alkylating agents: comparison of DNA alkylation of various rna ternal tissues and the embryo during organogenesis. In: D ~ Neubert, H. J. Merker, H. Nan and J. Langman ( eds). Role of pharmacokinetics in prenatal and perinatal toxicology, George Thieme Verlag, Stuttgart, PP. 235-261.

Bolander Jr., F.F. (1983). Persistent alterations in hormonal senstivities of mammary glands from parous mice. Endocrinol. 112: 1796-1800.

Boyland, E. and Ner1

y, R. (1969). Mercapturic acid formation during the metabolism of arecoline and arecaidine in the rat. Biochem. J. 113: 123-130.

Bresciani, F. (1965). Effect of ovarian hormones on duration of DNA synthesis in cells of the C3H mouse mammary gland. Exp. Cell. Res. 38: 13-82.

Bresciani, F. (1968). Topography of DNA synthesis mammary gland of the C3H mouse and i_ ts by ovarian hormones: An autoradiogra6hic Cell Tissue Kinet. I: 51-63. r

in the control study.

I I

Burg, A.W. and \.Jarner, E. (1972). Tissue ;distribution of caffeine,and its metabolites in the mouse. Biochem. Pharmacal. 21: 923-936.

Burton, K.A. (1956). A study of the conditions and mechanisms of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J. 62: 315-318.

Carroll, K.K. (1975). Experimental factors in hormone dependent 35: 3374-3383.

evidence of dietary cancer. Cancer Res.

Carroll, K.K., Hopkins, G.J. and Kennedy, T.G. (1982). relation to mammary carcino-20: 689-690.

Essential fatty acids in genesis. Prpg. Lipid Res.

Carroll, K.K. and Khor, H.T. (1971). Effects of level and type pf dietary fat on incidence of mammary tumors induced in female sprague~Dawley rats by 7,12-dimethylbenz[a] anthracene. Lipids,~: 415-420.

Cayen, I

M.N. and Dvornik, D. (1978). Combined clofibrate and diosgenin on cholesterol in rats. Atheroscler. 29: 317-327.

effects of metabolism

Page 4: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

Cayen, M.N. and on lipid 162-174.

115

Dvornik, D. (1979). metabolism in rats.

Effect of J. Lipid

diosgenin Res. 20:

Cayen, M.N., Ferdinandi, E.S., Graselin, E. and Dvornik, D. ( 1979). Studies on the disposition of diosgenin in rats, dogs, monkeys and man. Atherosclerosis 33: 71-87.

Cerecedo, L. R., Panzarella, E.C. (1952). Studies deficiency in three 48: 41-47.

F.P., Vasta, A.B., deRenzo, on the essential fatty acid

strains of mice. J. Nutri.

Chaube, S. and Murphy, M.L. (1968). of the ~ecent drugs active Adv. Teratol. 3: 181-237.

The teratogenic effects in cancer chemotherapy.

Chen, C.L. and Meites, J. (1970). Effects of estrogen and progesterone on serum and pituitary prolactin levels in ovariectomized rats. Endocrinol. 86:53-55.

Chopra, R.N. and Ghosh, S. (1925). Some observations on the pharmacological action and therapeutic properties of Adhatoela Vasica. Ind. J. Med. Res. fl= 205-212.

Chopra, R.N. (1933). Indigenous drugs of India.\ I

Chopra, R.N., Chopra, I.C. and Verma, B.S. (1969). Supplement to gloss\=ry of Indian medicinal plants. CSIR, New Delhi.

Chopra, R.N., Nayar, S.L. and Chopra, I.C. (1956). of Indian Medicinal plants. CSIR, New Delhi.

Clinton, S.K., Truex, C.R. and Visek, W.J. (1979). protein, aryl hydrocarbon hydroxylase and carcinogenesis in rats. J. Nutr. 109: 55-62.

Glossery

Dietary chemical

Cohen, L.A., Thompson, D.O., Maeura, Y., Choi, K., Blank, M.E. and Rose, D.P. (1986). Dietary fat and mammary cancer 1. Promoting effects of different dietary fat on N-Nitrosomethylurea-Induced rat mammary tumorigene~is. J. Natl. Cancer Inst. 77: 33-42.

Cole, H.O. (1933). The mammary gland of the mouse during estrous c~cle pregnancy and lactation. Proc. Roy. Soc. Lond.l (Biol.) 114: 136-161.

I --

Collins, T .F., (1981). caffeine Toxicol.

We~sch, J. J. , Black, T. N. and Collins, E. V. A study of the teratogenic potential of given by oral intubation to rats. Regul.

Pharmacal. 1: 355-378.

Page 5: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

116

Connors, T .A. (1975). Cytotoxic agents in teratogenic research. In: C.L. Berry and D.F. Poswillo (eds), Teratology, trends and applicatio~, Springer-Verlag, Berlin, Heidelberg, New York. pp.49-79.

Cowie, A.T. gland rats.

(1949). The relative growth in normal, gonadectomized and J. Endocrinol. 6: 146-157.

of the mammary adrenalectomized

Cowie, A. T., Folley, S .J. '· Mal press, F .H., Richardson, K.C. (1952). Studies on the hormonal induction of mammary growth and lactation in the goat. J. Endocrinol. 8: 64-88.

Cowie, A.T., Forsyth, I.A. and Hart, r.c'. (1980). Hormonal control of lactation. Monographs on endocrinology, Springer-Verlag, Berlin, Vol.15.

Daniel, C.W. (1975). mouse mammary 21_: 1-19.

Regulation of cell epithelium. Adv.

division in Exp. Med.

aging Biol.

Delouis, C., Djiane, J., Houdebine, L.M. and Terqui, M. ( 1980). Relation betwen hormones and mammary gland function. J. Dairy Sci. 63, 1492-~513.

Denda,

Dhawan,

A., Yokose, Y., Emi,. Y., Murata, Y., Quara, T., Sunagawa·, M., Mikani, S., Takana'si, S. and Konisho, Y. (1983). Effects of caffeine on pancreatic tumori­genesis by 4-Hydroxy-aminoquinone11-oxide in partially pancreatectomized rats. Carcinogenesis, 4: 17-22.

I

B.N., Dubey, M.P., Mehrotra, B.N., Rastogi, R.P. and Tandon, J .S. (1980). Screening of Indian plants for biological activity. Part JX. Indian J. Exp. Biol. 18: 594-606.

DiCarlo, R., Muccioli, G., Bellusi, Q., Portaleone, P., Ghi, P., Racca, S. and Di Carlo, :F. (1986). Steroid, prolactin and dopamine recept.drs · in normal and pathologic breast tissue. Ann~ N.Y. Acad. Sci. 464: 559-562.

Dixit, V.P., Khanna, P. and Bhargava, S.K. (1978). of Momordica Charantia L. Fruit extract testicular function of dog. 34: 280-286.

Effects on the

Donovan, P.J. and DiPaolo, J.A. (1974). of chemical carcinogen induced cultured syrian hamster cells. 2730-2737.

Darrington, J. and Gore-Langton, R.E. inhibits estrogen synthesis in (Lond) 290: 600-602.

Caffeine enhancement transformation of Cancer Res. 34:

(1981). Prolactin the ovary. Nature

Page 6: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

117

Dulbecco, R., Allen, W .. R., . Bologna, M. and Bowman, M. ( 1986). Marker evolution during the development of the rat mammary gland: Stem cells identified by markers and the role of myoepithelial cells. Cancer Res. 46: 2449-2456.

Dulbecco, R., Henahan, M. and Armstrong, B. (1982). types and morphogenesis in the mammary Proc. Natl. Acad. Sci. 79: 7346-7350.

Cell gland.

Dulbecco, R.' Unger, M.' Armstrong, B. • Bowman, M. and Syka, P. (1983). Epithelial cell types and their evolution in the rat mammary gland determined by immunological markers. Proc. Natl. Acad. Sci. USA. 80: 1033-1037.

Dunlop, M. and Court, J.M. (1981). Effects of maternal caffeine ingestion on neonatal growth in rats. Biol. Neonate. 39: 178-184.

Enami, J. , Enami, S. and Koga, M. (1983). Grm.,rth of normal and neoplastic mouse mammary epithelial cells in primary culture: Stimulation by conditioned medium from mouse mammary fibroblasts. Gann. 74: 845-853.

Faulkin, L.J., Abraham, S., Mitchell, D.J. and Hillyard, L.A. (1986). Effects of dietary fat on mammary development relative to age and hormones in BALB/c mice. Proc. Soc. Exp. Biol. Med. 181: 575-585.

Faulkins, L.J. and DeOme, K.B. (1960). Regulation of growth and spacing of gland elements in the mammary fat pad of the C3H mouse. J. Natl. Cancer Inst. 24; 953-963.

FendeJI, L.D. and Smith, J.R. (1970). Betel nut associated cancer report of case. J. Oral Surg. 28: 455-456.

Floss, H.G., Cassady, J.M. and Robbers, J.E. (1973). Influence of Ergot alkaloids on pituitary prolactin and prolactin~dependent processes. J. Pharm. Sci~ 62: 699-715.

Foster, R.C. (1977). Changes in the mouse mammary epithelial cell size during mammary gland development. Cell Different. £: 1-8.

Fried, P.A. and O'Connell, C.M. (1987). A comparison of the effects of prenatal exposure to Tobacco, Alcohol, cannabis and caffeine on birth size and subsequent growth. Neutotoxicol. Teratol. 2: 79-85.

Page 7: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

118

Friedberg, S.H., Oka, T. and Topper, Y.J. (1970). Development of insulin sensitivity by mouse mammary gland in vitro. Proc. Natl. Acad. Sci. U.S.A. 67: 1493-1500.

Fujii, T. and Nishimura, H.(l972). Adverse effects of prolonged administration of caffeine on rat fetus. Toxicol. Appl. Pharmacal. 22: 449-457.

Fulkerson, W.J. and induction · of 63: 167-173.

McDowell, lactation

G.H. (1974). in ewes. J.

Artificial Endocrinol.

Fulkerson, W.J., McDowell, G.H. and Fell, L.R. (1975). Artificial indue tion of lactation in ewes: the role of prolactin. Aust. J. Biol. Sci. 28: 525-530.

Furuhashi, N., Sato, S., Suzuki, M., Hiruta, M., Tanaka, M. and Takahashi, T. (1985). Effects of caffeine ingestion during pregnancy. Gynecol. Obstet. Invest. 1.2.: 187-191.

Gaitonde, B.B. and Jetmalani, M.H. (1969). Antioxytocic action of saponin isolated from Asparagus racemousus willd. (Shatavari) on uterine muscle. Arch. Int. Pharmacodyn. 179: 121-129.

Gandilhon, P., Melancon,~. and Djiane, K. (1982). Comparison of ovariectomy and retinyl acetate on the growth of established 7,12-dimethyl benz[a] anthracene induced mammary tumors in the rat. J. Natl. Cancer Inst. 69 447-451.

Gardner, W.U. (1940). Growth of the hypophysectomized mice. Proc. Med. 45: 835-837.

mammary glands in Soc. Expt. Biol.

Garg, S.K. and Garg, G.P. (1971). Antifertility screening of plants. VII. Effect of five indigenous plants on early pregnancy in albino rats. Ind. J. Med. Res. 59: 302-306.

Gilbert, E.F. and Pistley, W.R. (1973). Effect on the oppspring of repeated caffeine administration to pregnant rats. J. Reprod. Fertil. 34: 495-499.

* Gilbert, R.M. (1976). Caffeine as a drug of abuse. In: R.J. Gibbins, Y. Israel, H. Kolant, R.E. Popham, W. Schmidt and R.G. Smart (eds), Research advances in alcohol and drug problems. John Wiley and Sons, New York. Vol. III: 49-75.

Page 8: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

119

Goldstein, A. and Warren, R. (1962). Passage of into human gonadal and fetal tissue. Pharmac. 11: 166-168.

caffeine Biochem.

Grobstein, C. (1967). Mechanisms of organogenetic tissue interaction. Natl. Cancer Inst. Monogr. 26: 279-299.

i

Gupta, O.P., Sharma, M.L., Ray Ghatak, B.J. and Atal, C.K. (1977). Potent uterine activity of alkaloid vasicine. Ind. J. Med. Res. 66: 865-871.

Gupta;

'

V.N., Jain, Synthesis ll: 74-75.

M.P., A tal, of vasicine

C.K., Bhardawaj, analogues. Ind.

M. (1982). J. Chern.

Gurkaio, V.K. and Zabezhinski, M.A. (1982). On participation of autonomic nervous system in the mechanism of chemical carcinogenesis. Neoplasma. ~: 301-307.

Harbison, R.D. (1980). Teratogens. In: Toxicology, J. Donll, C.D. Klasseu and M.O. Amdur (Eds), MacMillan, New York, pp. 158-175.

Harness, J.R. and Anderson, R.R. (1975). Effect of relaxin on mammary gland growth and lactation in the rat. Proc. Soc. Exp. Biol. Med. 148: 933-936.

Hart, I

I.C. and Morant, S.V. (1980). Roles of prolactin, growth hormone, insulin and thyroxine in steroid-induced lactation in goats. J. Endocrinol. 84: 343-351.

Haslam, S.Z. and Shyamala, G. (1981). Relative distribution of estrogen and progesterone receptors among the epithelial, adipose and connective tissue components of the mammary gland. Endocrinology. 108: 825-830.

Hawrylewicz, E.J., Huang, H.H. and Kissane, J.Q. (1982). Enhancement of 7,12-dimethylbenz[a) anthracene (DMBA) mammary tumorigenesis by high dietary protein in rats. Nutr. Rep. Int. 26: 793-896.

Hilgers, J. and Sonnenberg, tumorigenesis. In: and human pathology, Press, Amsterdam, pp.

A. ( 1985). Viral and non viral J. Hilgers (ed), Reteroviruses Elsevier/North-Holland Biomedical 87-99.

Hirono, I. (1981). Natural carcinogenic products of plant origin. Crit. Rev. Toxicol. ~: 235-277.

Hogg, N.A.S., Harrison, C.J. and Tickle, C. (1983). formation in the developing mouse mammary J. Embryol. and Expt. Morpho~. 73: 39-57.

Luman gland.

Page 9: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

120

Hooley, R.D., Canbell, J.J. and Feudlay, J.K. importance of protactin for lactation J. Endocrinol. 79: 301-310.

(1978). The in the ewe.

Hoshino, H. and skin tumor 83-85.

Tanooka, H. (1979) . induction in mice.

Caffeine Toxicol.

enhances Lett. 4:

Imagawa, W., Tomooka, Y., Hamamoto, S. and Nandi, S. (1985). Stimulation of mammary epithelial cell growth in vitro: Interaction of epidermal growth factor and mammogenic hormones. Endocrinology 116: 1514-1524.

International Agency for Research on Cancer (1985). Evaluation of the carcinogenic risk of chemicals to humans: Tobacco habbits other than smoking: Betel-quid and areca nut chewing, and some related nitrosamines. IARC Monogr. 37: 141-200.

*Jacobsohn, D. (1961). In: The mammary gland and its secreti.on. S.K. Kon and A.T. Cowie (Eds). 127-160.

Jacobson, S.W., Fein, G.G., Jacobson, J.L., Schwartz, P.M. and Dowler, J.K. (1984). Neonatal correlates of prenatal exposure to smoking, caffeine and alcohol. Infant Behav. Dev. 7: 253-265.

Kakakunga, T. (1975). Caffeine inhibits cell by 4-Nitroquinoline-1-oxide. Nature

transformation 258: 248-250.

Kapadia, J.T., Chung, E.B., Ghohs, B., Shukla, Y.N., Basak, S.P., Morton, J.F. and Pradhan, S.N. (1978). Carcino­genicity of some folk medicinal herbs in rats. J. Natl. Cancer Inst. 60: 683-686.

Keelar, R.F., Young, S. and Brown D. (1976). exencephaly and cranial bleb produced alkaloid solasodine. Res. Commun. Pharmacal. Jl: 723-730.

Spina bifida, by the solanum Chern. Pathol.

King, M.M., Bailey, D.M. and Gibson, D:D. (1979). Incidence and growth of mammary tumors induced by 7,12-dimethylbenz[ a] anthracene as related to the dietary content of fat and antioxidant. J. Natl. Cancer Inst. 63: 657-663.

Kleinberg, D.L. and Newman, C.B. (1986). The pituitary gland in primate mammary development: Evidence that prolactin is not essential. Ann. N.Y. Acad. Sci. 464: 37-43.

Page 10: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

121

Kleinberg, D.L., Niemann, W., Flamm, E., Cooper, P., Babitsky, G. and Valensi, Q. (1985). Primate mammary development: Effects of hypophysectomy, Prolactin inhibition and growth hormone administration. J. Clin. Invest. 1..2: 1943-1950.

Knazek, R.A., Lin, S.C., Bodwin, J.S. and Vonderhaar, B.K. (1980). Requirement of essential fatty acids in

Leavitt,

the diets for development of the mouse mammary gland. J. Natl. Cancer Inst. 64: 377-382.

w. w.' Chen, T,J.' Allen, T.C. (1978). receptors. In: B.W. (Eds), Receptors and

Do,

Potentiation of prosta­of isolated rat uterus Ind. J. Med. Res. 73:

y .s.' Carlton, B.D. and Biology of progesterone

O'Malley and L. Birnbaumer hormone ac tio11. Vol. II.

Acad. Press, New York, pp. 157-188.

Leavitt, W.W., Toft, D.O., Strott, C.A. and O'Malley, B.W. (1974). hamster during 1053.

A specific progesterone receptor in the uterus, physiologic properties and regulation the estrus cycle. Endocrinol. 94: 1041-

Ledinko, N. and Evans, M. ( 1973). transformation of hamster

Enhancement of adenovirus cells by N-methyl-N-

nitrosoguanidine, caffeine and hydroxylamine. Cancer Res. 33: 2936-2938.

Levine, J.F. and Stockdale, F.E. (1984). promote the growth of mammary Cell Res. 151: 112-122.

3T3-LI adipocytes epithelium. Exp.

Caffeine metabolism Levy, M. and Zylber-Katz, E. (1982). and coffee attributed sleep Pharmacal. Ther. 33: 770-775.

disturbance. Clin.

Lu, K.H., Amenomori, Y., Chen, C.L. and Meites, J. (1970). Effects of central acting drugs on serum and pituitary prolactin levels in rats. Endocrinol. 87: 667-672.

Page 11: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

122

Lyons, W.R., Li, C.H. and Johnson, R.E. (1958). The hormonal control of mammary growth and lactation. Rec. Prog. Horm. Res. ~: 219-250.

Lyons, W.R. and McGinty, D.A. (1941). Effects of estrone and progesterone on male rabbit mammary glands I. Varying doses of progesterone. Proc. Soc. Exp. Biol. Med. 48: 83-89.

Malberger, E., Gutterman, E., Bartfield, E. and Zajicek, mammary gland cycle. Acta

G. (1987). Cellular changes in the epithelium during the menstrual Cytologica. 31: 305-308.

Manni, A., Badger B., Wright, C., Ahmed, S.R. and Demers, L.M. (1987). Effects of progestins on growth on experimental breast cancer in culture: Interaction with estradiol and prolactin and involvement of the polyamine pathway. Cancer Res. 47: 3066-3071.

Mathew, A.G., Venkataraman, S.D. and Govindrajan, V.S. (1963). Studies on Arecanut: Part I Changes in chemical composition and physical characteristics on nuts with maturity. Indian J. Technol. 2: 90-96.

Hauvais-Jarvis, P., Kuttenn, F. and Gompel, A. (1986).

Mayers,

McCann,

Antiestrogen action of progesterone in breast tissue. Breast Cancer Res. and Treat. 8: 179-188.

J.A. (1919). Studies on the mammary gland IV. The histology of the mammary gland in male and female albino rats from birth to ten weeks of age. Am. J. Anat. 25: 394-435.

S.M., Mack, R. and Gale, C. (1959). role of oxytocin in stimulating the prolactin. Endocrinol. 64: 87~-889~

The possible release of

Medicinal plants of India, Vol. I. (1976). of Medical Research, New Delhi.

Indian Council

Mehrotra, P.K. and Kamboj, V.P. (1978). of coronairidine hydrochloride agent of plant origin. Planta 349.

Hormonal profile an antifertility Medica. 34: 345-

Mehta, R.G. and Banerjee, M.R. promoting hormones on during lobulo-alveolar mammary gland in organ 80: 501-516.

(1975). Action of growth­macromolecul~r biosynthesis

development of the entire culture. Acta Endocrinol.

Page 12: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

123

Meltzbl r, L. T. and Rosecrans, the disruptive effects controlled behaviour.

J. A. ( 1982). Tolerance to of arecoline on schedule­Psychopharmacology 78: 150-

. 155.

Mester, J. and Baulieu, E. (1984). synergy and antagonism Biochem. Sci. 9: 56-59.

Effects of progesterone: with oestrogens. Trends

Meyer, B.N., Wall, M.E., Wani, M.C. and Taylor, H.I. (1985). Plant antitumor agents, 21. Flavones coumarins and an alkaloid from Sarg~ntia greggii. J. Natur. Prod. 48: 952-956.

Minton, J.P., Abou-isoa, H., Foecking, M.K. and Sriram, M.G. (1983). Caffeine and unsaturated diet significantly promotes D.M.B.A.-induced breast cancer in rats. Cancer, 11: 1249-1253.

Miyamoto-Tiaven, M.J., Hillyard, L.A. and Abraham, Influence of dietary fat on the growth ducts in BALB/C mice. J. Natl. Cancer 179-188.

s. (1981). of mammary Inst. 67:

Molinengo, L., Cassone, M.C. and Orsetti, M. (1986). Action of arecoline on the levels of acetylcholine, norepine­phrine and dopamine in the mouse central nervous system. Pharm. Biochem. Behav. 24: 1801-1803.

Montgomery, In:

D. (1976). Experiments with a single factor. Douglas C. Montgomery (ed), Design and analysis

of experiments, John Wiley and Sons, New York. pp.33-70.

Moon, R.D., Griffith, D.R. and Tu!)ner, C.W. (1959). and experimental growth i of rat mammary Proc. Soc. Exp. Biol. Med. 101: 788-790.

Moon, R.C., Thompson, H.J.' Becti, P.J. (1979). hydroxyphenyl) retinamide, a new retinoid prevention of breast cancer in the rat. Res. 39: 1339-1346. I

Normal gland.

N-(4-for

Cancer

Page 13: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

124

Muldoon, T.G. (1986). Steroid hormone receptor regulation by various hormonal factors during mammary develop­ment and growth in· the normal mouse. Ann. N.Y. Acad. Sci. 464: 17-36.

Murphy, M.L., Moro, A.D. and Lacon, C.R. (1958). The compara­tive effects of five polyfunctional alkylating agents with additional notes on the chick embryo. Ann. N.Y. Acad. Sci. 68: 762-782.

Nagasawa, H~ (1982). Role of prolactin or placental lactogen in mammary tumor development in experimental animals. In: B.S. Leung (ed), Hormonal regulation of mammary tumors, Vol. II. Eden Press, Montreal, pp. 1-25.

Nagasawa, H.' Aoki, M. and Mori, A.T. (1987). Effects of different schedules of progesterone treatment on mammary tumorigenesis and uterine adenomyosis in SHN virgin mice. Life Sci. 40: 2597-2602.

Nagasawa, H., Fujii, M. and Hogiwara, K. (1985). Inhibition by medroxy-progesterone acetate of precancerous mammary hyperplastic alveolar nodule formation in mice. Breast Cancer Res. and Treat. 5: 31-36.

Nagasawa, H., Ohta, K., Nakajima, K., Noguchi, Y., Miura, K., Niki, K. and Namiki, H.C. (1986). Inter­relationship between pituitary and ovarian hormones in normal and neoplastic growth of mammary glands of mice. Ann. N.Y. Acad. Sci. 464: 301-315.

Nagasawa, H. and Sakurai, N. (1986). Effects of ingestion of caffeine on mammary ;rowth and duction in mice. Life Sciences 39: 351-357.

chronic repro-

Nagasawa, H. and Yanai, R. (1972). Inhibitory effect of estrogen on mammary growth and its counteraction by pituitary isograft in mice. Endocrinol. Jpn. 19: 107-110.

Nagasawa, H., Yanai, R., Iwahashi, H., Fujimoto, M. and Kuretani, K. (1967). Effect of pituitary isografts on the growth of spontaneous mammary tumor in mice. Gann. 58: 337-342.

Nagasawa, H., Yanai, R., Nakajima, Y., /Namiki, H., Kihuyama, S. and Shiota, K. (1980). Inhibitory effects of potassium thiocyanate on normal and neoplastic mammary development in female mice. Eur. J. Cancer 16: 473..:.;480.

Page 14: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

125

Nakagj wa, I., Sasaki, A., Kajimoto, M., Fukuyama, T., Suzuki, r T. and Yamada, E. (1974). Effect of protein, nutrition on growth, longevity and incidence of lesions in the rat. J. Nutr. 104: 1576-1583.

;~andi, S. ( 1958). Endocrine control of mammary gland develop­ment and function in the C3H/He Crgl Mouse. J. Natl. Cancer Inst. 21: 1039-1062.

0:­

Nandi, S. (1959). Hormonal control I

lactogenesis in the C3H/1He Calif. Publ. Zool. 65: 1-128.

of mammogenesis and Cragl mouse. Univ.

Nathanson, I.T., Shaw, D.T. and Franseen, C.C. (1939). Effect of simultaneous administration of growth complex and estradiol on mammary gland of hypophy­sectomized rat. Proc. Soc. Exp. Biol. Med. 42: 652-655.

Navlor, B. and Poyser, N.L. (1975). Effects of oestradiol and progesterone on the in vitro production of prostaglandin F2 by the guinea pig uterus. Brit. J. Pharmacal. 55: 229-232.

Nery, R. (1971). The metabolic interconversion of arecoline and arecoline 1-oxide in the rat. Biochem. J. 122: 503-508.

Neville, M.C. (1983). Regulation of mammary development and lactation. In: Margaret, C. Neville and Marianne, R. Neifert (eds), Lactation, Plenum Press. pp. 104-140.

Neville, M.C.(1987). Mammary cultures on A model system for mammary function. Sci. 2: 107-111.

* j

floating gels: News in Physiol.

Nieschulz, 0. and Schmersahl; P. (1967). in betel (Areca catechu).

Effective substances Naturwissenschaften.

54: 21. I

Nolen, G.A. (1982). A reproduction/teretology study of brewed and instant decaffeidated coffees. J. Toxicol. Environ. Health. 10: 769-783.

Nomura, T. (1976). Diminuation of tumorigenesis initiated by 4-nitroquinoline-1-oxide by post treatment with caffeine in mice. Nature (London), 260: 547-549.

Page 15: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

126

Oka, T., f?erry, J.W. and Topper, Y.J. (1974). Changes in insulin responsiveness during development of mammary epithelium. J. Cell Biol. 62: 550-556.

Oka, T. and Topper, Y.J. (1972). Is for mammary epithelium? Proc. USA 69: 1693-1696.

prolactin mitogenic Natl. Acad. Sci .•

Ormerod, E.J. and Rudland, P.S. (1984). Cellular composition and organization of ductal buds in developing rat mammary glands. Evidence for morphological inter­mediates between epithelial and myoepithelial cells. Amer. J. Anatomy 170: 631-652.

Ota, H., Wakizaka, A. and Furushima, M. (1986). Modulation of ovarian LH receptor and serum hormone levels in rats with hyperprolactinemia induced by adminis­tration of ovine prolactin or sulpiride. Tohoku J. Exp. Med. 148: 213-217.

Overstreet, D.H., Booth, R.A., Dana, R., Risch, S.C. and Janowsky, D. S. (1986). Enhanced elevation of corti­costerone following arecoline administration to rats selectively bred for increased cholinergic function. Psychopharmacology 88:-129-130.

(1986). Behavioural tolerance Overstreet, D.H. Jamal, O.S. to arecoline in rats: and prevention by Psycopharmacology 89:

Cross tolerance to oxtremorine pretreatment with atropine.

118-120.

Packard, D.S. Jr., Men~ies, R.A. and Skalko, R.G. (1973). Incorporation of thymidine and its analogue, bromo­deoxyuridine into embryos and maternal tissues of the mouse. Differentiation 1: 397-405.

Panigrahi, G.B. and Rao, A.R. (1982). Chromosome breaking ability of arecolin~, a major betel nut alkaloid, in mouse bone marrow cells in vivo. Mutat. Res. 103: 197-204.

Panigrahi, G.B. and Rao, A.R. (1983). Influence of caffeine on arecoline-induced SCE in mouse bone-marrow cells in vivo. Mut. Res. 122: 347-353.

Panigrahi, G.B. and Rao, A.R. (1986). Study of the genotoxi­city of the total aqueous extract of betel nut and its tannin. Carcinogenesis. 2: 37-39.

Patel, A.B. and Kanitkar, V .K. willd from Bordi as a Ind. Vet. J 46: 718-724.

(1969). Asparagus racemosus galactogogue in buffaloes.

Platzek, T., Bachert, G. and Rahm, V. (1983). , Embryotoxici ty induced by alkylating agents. Teratogenicity of acetoxymethyl-methyl nitrosamine: Dose response relationship applicat-ion route dependency and phase specificity. Arch. Toxicol. 52: 45-69.

Page 16: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

127

Platzek, T., Bachert, G., Schneider, W. and Neubert, D. ( 1982). Embryotoxicity induced by alkylating agents: I. Ethylmethane sulfonate as a teratogen in mice. A model for dose response relationships of alkylating agents. Arch. Toxicol. 51: 1-25.

Pozniak, P. (1985). The coffee: a review. 1133.

carcinogenicity J. Am. Diet

of caffeine and Assoc. 85: 1127-

Pradham, S.N. and Datta, of arecoline in 49-58.

S.N. (1970). Behavioral effects rats. Psychopharmacologia. 17:

Prakash, A.O. and Mathur, R. (1979). Studies on oestrous cycle of albino rats. Response to Embelia ribes extracts. Planta Medica. 36: 134-141.

Pyska, H., Styczynski, H. (1979). Effects of various protein levels in the diet on mammary gland growth in rats. J. Dairy Res. 46: 551-554.

Radcliffe, J.D. and Moon, R.C. (1983). Effect of N-(4-hydroxyphenyl) retinamide on feed intake, grwoth and mammary gland development in rats. Proc. Soc. Exp. Biol. Med. 174: 270-275.

Radner, C.P. (1972). Myoepithelial cell differentiation on rat mammary glands. J. Anat. 111: 381-398.

Ranadive, K.J., Gothoskar, S.V., Rao, A.R., Tezabwalla, B.U. and Ambaye, R.Y. (1976). Experimental studies on betel nut and tobacco carcinogenicity. Int. J. Cancer 17: 469-476.

Rao, A.R. (1981). Inhibitory action of Asparagus racemosus on DMBA-induced mammary carcinogenesis in rats. Int. J. Cancer 28:607-610.

Rao,

Rao,

A • R. (1984) . ingredients the buccal 581-586.

Modifying influences of betal quid on B(a)P induced carcinogenesis in

pouch of hamster. Int. J. Cancer 33:

M.N.A., Krishnan, Synthesis of for oxytocic J. Pharm. Sci.

S., Jain, M.P. and Anand, K.K. (1982). vas1c1ne and vas1c1none derivatives and bronchodilatory activity. Ind.

44: 151-153.

Page 17: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

128

Raynaud, A. (1961). Morphogenesis of the mammary gland.

Reece,

In: S. K. Kon and A. T. Cowie ( Eds), Molk: The mammary gland and its secretion, Vol. I. pp. 3-46.

R. p.' gland rat.

Turner, C.W. and Hill, A.T. (1936). development in the hypophysectomized

Proc. Soc. Exp. Biol. Med. 34: 204-207.

Mammary albino

Risch, S.C., Siever, L.J., Gillin, J.C., Janowsky, D.S., Sitaram, N., Weker, J., Cohen, R.M. and Murphy, D.L. (1983). Differential mood effects of arecoline in depressed patients and normal volunteers. Psychopharmacol. Bull. 12: 696-698.

Rivera, E.M. (1971). Mammary.gland culture. In: J.C. Daniel and Jr. W.H. Freeman (Eds), Methods in mammalian embryology. Co. San Fransisco, pp. 442-471.

Rogers, A.E. and Wetsel, W.C. (1981). Mammary carcinogenesis in rats fed different amounts and types of fat. Cancer Res. 41: 3735-3737.

Rolland, R., Dejong, F.H., Schellekens, L.A. and Lequin, R.M. (1975). The role of prolactin in the restoration of ovarian function during the early post partum period in the human female. II. A study during inhibition of • lactation by bromoergocryptine. Clin. Endocrinol. 4: 27-38.

Rothwell, k. (1974). Dose related carcinogenesis in mouse skin (London), 252: 69-70.

inhibition of by caffeine.

chemical Nature

Rudland, P.S., Bennett, D.C., Ritter, M.A., Newman, R.A. and Warburton, M.J. (1980). Differentiation of a rat mammary stem cell line in culture. In: L. Jiminez de Asna, R. Lovi, Montalcini, R. Shields and S. Jacobelli (Eds), Control mechanisms in animal cells. Raven Press, New York. pp. 341-365.

Russo., I. H. and Russo, J. (1978). Development stages of the rat mammary gland as. a determinant of its susceptibility to 7,12-dimethylbenz[a] anthracene. J. Natl. Cancer Inst. 61: 1439-1449.

Russo, J., Tay, L.K. and Russo, I.H. (1982). Differentiation of the mammary gland and susceptibility to carcino­genesis. Breast Cancer Res. Treatm. 2: 5-73.

Page 18: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

129

Sabnis, P.B., Gaitonde, B.B. and Effect of alcoholic extract on mammary glands of rats. .§.: 55-57.

•.. ~._.

Jetmalani, M. (1968). of Asparagus racemosus

Ind. J. Exptl. Biol .

Mesenchyme specific Science

Sakakura, T., Nishizuka, T. and Dawe, C.J. (1976). dependent morphogenesis and epithelium cytodifferentiation in mouse mammary gland. 194: 1439-1441.

Sakakura, T. , tence gland Biol.

Sakagami, Y. and Nishizuka, Y. (1979). Persis­of responsiveness of adult mouse mammary to induction by embryonic mesenchyme. Dev.

72: 201-210.

Sakakura, T., Sakagami, Y., Nishizuka, Y. (1982). Dual origin of mesenchymal tissues participating in mouse mammary gland embryogenesis. Develop. Biol • .21_: 202-208.

Samson, W.K., Lumpkin, M.D. and McCann, S.M. (1986). Evidence for a physiological role for oxytocin in the control of protactin secretion. Endocrinol. 119: 554-560.

Sanz, M.C.A., Liu, J., Huang, H.H. and Hawrylewicz (1986). Effect of dietary protein on morphologic development of rat mammary gland. J. Natl. Cancer Inst. 77: 477-487. •

Schams, D. and Karg, H. (1972). The immediate response of the prolactin levels to estrogen infusions in dairy cows. Acta Endocrinol. 69: 47-52.

Schams, D., Russe, I., Schallenberger, E., Prokopp, S. and Chan, J .S.D. (1984). The role of steroid hormones, prolactin and placental lactogen on mammary gland development in ewes and beifers. J. Endocrinol. 102 : 121-130.

Sheffield, L.G., Sinha, Y.N. and Welsch, C.W.(1985). Cholera toxin treatment increases in vivo growth and develop­ment of the mouse mammary gland. Endocrinol. 117: 1864-1869.

Shivapurkar, N.M., Ranadive, S.N., Gothoskar, S.V., Bhide, S.V. and Ranadive, K.V. (1980). Tumorigenic effect of aqueous and polyphenolic fraction of betal nut in swiss strain mice. Indian J. ~xp. Biol. 18: 1159-1161.

Page 19: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

130

Shyamala, G.' Ferenezy, A. (1984). Mammary fat pad may be a potential site for initiation of estrogen action in normal mouse mammary glands. Endocrinology 115: 1078-1082.

Silberstein, G.B., Strickland, P., Trumpbour, V., Coleman, S. and Daniel, C.W. (1984). In vivo, cAMP stimulates growth and morphogenesis of mouse mammary ducts. Proc. Natl. Acad. Sci. USA. 81: 4950-4954.

Sinha, A. (1984). Teratogenicity and carcinogenicity studies of betel nut on mice. Ph.D. thesis (unpublished), Jawaharlal Nehru University, New Delhi.

Sinha, A. and Rao, A.R. (1985). Embryotoxicity of betel nuts in mice. Toxicol. 37: 315-326.

Sinha, Y .N. and Tucker, (1966). of rats between 0 and 100 Physiol. 210: 601-665.

Mammary days of

gland growth age. Am. J.

Sitaram, N., Weingartner, H. and Gillin, J.C. (1978). Human serial learning: Enhancement with arecoline and choline and impairment with scopolamine. Science 201: 274-276.

Sonnenberg, A., Daams, H., Van Der Valk, M.A., Hilkens, J. and Hilgers, J. (1986). Development of mouse mammary gland: ldentification of stages in differ­entiation of luminal and myoepithelial cells using monoclonal antibodies and polyvalent antiserum against keratin. J. Histochem. Cytochem. 34: 1037-1046.

Spindel, E. (1984). The methylxanthine beverages and foods: Consumption and health effects. G.A. Spiller (ed), Alan R. Liss. Inc. New York. 355-363.

Spindel, E., Arnold, M., Cusack, B. and Wurtman, R.J. (1980). Effects of caffeine on anterior pituitary and thyroid function in the rat. J. Pharmacal. Exp. Ther. 214: 58-62.

Spindel, E., Griffith, L. and Wurtman, J. (1983). Neuro­endocrine effects of caffeine. II. Effects on thyrotropin and corticosterone secretion. J. Pharmacal. Exp. Ther. 225: 346-350.

Squartini, F. (1983). The mammary lobules in cancerous breast: Human findings and experimental background. In: K.H. Hollman and J.M. Verley (eels), New frontiers in mammary pathology, Vol. 2. Plenum Press, New York, pp. 165-210.

Page 20: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

131

Stich, H.F. and Stich, W. 1(1982). Chromosome damaging activity of saliva of betel nut and tobacco chewers. Cancer Lett. 15: 193-202.

Stich, H. F., Stich, W. and Lam, P.P.S. (1981). Potentiation of ~enotoxicity by concurrent application of compounds found in betel quid: atzl.coline, eugenol, quercetin, chlorogenic acid and Mn • Mutation Res. 90: 355-363.

Strum, J.M. (1979). A mammary gland whole mount that preserves cell fine structure for microscopy. J. Histochem. Cytochem. 27:

technique electron

1271-1274

Subramanian, M.G. and Gala, R.R. (1976). The influence of cholinergic, adrenergic and seratonergic drugs on the afternoon surge of plasma prolactin in ovariectomized, estrogen-treated rats. Endocrinol. 98: 842-848.

Subramanian, M.G. and Gala, R.R. (1977). Specificity of arecoline and apomorphine and the site of actien of arecoline in inhibiting the diurnal prolactin surge. Proc. Soc. Exp. Biol. Med. 155: 353-356.

Takanashi, H., Umeda, M. aberrations an~

cells induced by Re. 78: 67-77.

and Hirano, I. mutation in pyrrolizidine

(1980). cultured

alkaloids.

Chromosomal mammalian Mutation

Takayama, S. and Kuwahara, N. (1982). Long on the effect of caffeine in Wistar 11: 365-371.

term rats.·

study Gann,

* Tanimura, T. (1968). Relationship of dosage and time of thiotepa

Anatomica administration to teratogenic effects of in mice. Sonderabdruck OkuJ~mas folia. Japonica 44: 203.

Tannenbaum, A. and Silverstone, H. (1949). The genesis and growth of tumors IV. Effects of varying the proportion of protein (casein) in the diet. Cancer Res. 49: 162-173.

Theiss, J.C. and Shimkin, M.D. (1978). Inhibiting effect of caffeine on spontaneous and urethan-induced lung tumors in strain A mice Cancer Res. 38: 1757-1761.

Page 21: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

132

Topper, Y.J. and Freeman, C.S. (1980). Multiple interactions in the developmental biology mammary gland. Physiol. Rev. 60: 1049-1105.

hormone of· the

Topper, Y.J., Nicholas, K.R., ~hankaran, L. and Kulski, J.K. (1984). Insulin biblogy from the perspective of studies on mammary gland development. Biochem. Action Harm. Vol. XI: 163-186.

Trenin, G.G. (1951). Relaxin and mammary growth in the mouse. Proc. Soc. Exp. Bioi. Med. 78: 9-11.

Turner, C. V. and Gomez, E. T. ( 1933). The normal development of the mammary gland of . the male and female albino mouse. Mo. Agric. Station Res. Bull. 182: 3-20.

Uchida, K., Takase, H. ' Nomura, y.' Takeda, K.' Takenchi, N. and Ishikawa, Y. (1984). Changes in biliary and fecal bile acids in mice after treatments with diosgenin and beta-sitosterol. J. Lipid Res. 25: 236-245.

* Vale, W., Rivier, C., Brown, M., Chan, L., Ling, N. and

Vane,

Rivier, J. (1976). In: F. Labrie, J. Meites and G. Pelletier (eds}~, Hypothalamus and endocrine functions, Plenum Press, New York, pp. 397.

J.R. (1971). Inhibition of as a mechanism of action Nature, New Biol. 231: 232.

-- i

prostagland in synthesis for aspirin like drugs.

Wada, H., Turner, C.W. (1959). Effect of relaxin on mammary

Wagner,

Wang ,

gland growth in female. mice. Proc. Soc. Exp. Bioi. Med. 101: 707-709.

H. and Wolff, P. (1977). In: New natural products and plant drugs with ./pharmacological, biological or therapeutical activity. H. Wagner and P. Wolff (Eds). Springer-Verlag.

C. and Chan, V. (1982). Divergant effects of prolactin on estrogen and progesterone. production by granulosa cells of rat graffian follicles. Endocrinol. 110: 1085-1093.

Wang, C., Hsueh, A.J.W. and Erickson, G.F. (1980). Prolactin inhibition of estrogen production by cultured rat gransulosa cells. Mol. Cell Endocrinol. 20: 135-144.

Page 22: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

133

Watkinson, B. and Fried, P.A. (1985). Maternal caffeine use before, during and after pregnancy and effects upon offspring. Neurobehav. Toxicol. Teratol. 7: 9-17.

Wealth of India (1948-1956). Council for Scientific and Industrial Research, New Delhi.

Weathersbee, P.S., Ax, R.L. and Lodge, J.R. (1975). Caffeine mediated changes of sex ratio in chinese hamsters, cricetulus griseus. J. Reprod. Fertil. 43 :141-143.

Weathersbee, P.S. and Lodge, J.R. (1977). direct and indi~ect influence on J. Reprod. Med. 19: 55-63.

Caffeine: its reproduction.

Weiner, R.I. and Bethea, C.L. (1982). Hypothalamic control of prolactin secretion. In: Louis, V. A. Violi (Ed), Current Endocrinology. pp. 19-51.

Welsch, C.W. and Aylsworth, C.F. (1983). Enhancement of murine mammary tumorigenesis by feeding high levels of dietary fat. A hormonal mechanism. J. Natl. Cancer Inst. 70: 215-221.

Welsch, C. W., De Hoog, .J. V., 0 'Connor, D.H. and Sheffield, L.G. (1985). Influence of dietary fat levels on development and hormone responsiveness of the mouse mammary gland. Cancer Res. 45: 6147-6154.

Welsch, C.W. and Nagasawa, H. mammary tumorigenesis: 951-963.

(1977). Prolactin and murine A review. Cancer Res. 37:

Welsch, C.W., Sciescka, K.M., Senn, E.R. and De Hoog, J.V. (1983). Caffeine (1,3,7-trimethylxanthene), A tempera­te promotor of DMBA-induced rat mammary gland carcino­genesis. Int. J. Cancer 32: 479-484.

Welsch, U., Singh, S., Buchhcim, W., Patton, S. (1984). Internalisation of ferritin-concanavalin A by the lactating mammary cell in vivo. Cell Tissue Res. 235: 433-438. '

Williams, J.M. and Daniel, C.W. (1983). Mammary duct elonga­tion: Differentiation of myoepitheliam and basal lamina during branching morphogenesis. Dev. Biol. 97: 274-290.

Winterhoff, S.H., Gumbinger, H.G. Antihormonal effects of Medica. 45: 78-86.

and Kemper, F.H. plant extracts.

(1982). Planta

Page 23: J. - Shodhganga : a reservoir of Indian theses @ INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/16305/12/12... · Prpg. Lipid Res. Carroll, ... A study of the teratogenic potential

*

*

134

Yamanaka, H. , Nagao, M. , Sugimura, T. , Furuya, T. , Shirai, A. and Matsushima, T. (1979). Mutagenicity of pyrrolizidine alkaloids in the salmonella/mammalian­microsome test. Mutation Res. 68: 211-216.

Yanai, R. and Nagasawa, H. (1971). Enhancement by pituitary isografts mammary hyperplastic nodules in adreno ovariectomized mice. J. Nat1. Cancer Inst. 46: 1251-1255.

Yang, J.A., Huber, S.A. and Lucas, Z.J. (1979). of DNA synthesis in cultured lymphocytes cells by extracts of betel nut, tobacco leaf. Plant substances associated with the Oro-respiratory epithelium. Cancer 4802-4809.

Zetterberg, G. (1959). The mutagenic effect of caffeine, caffei~e and dimethylsulphate ophiostoma back mutation test. Hereditas, 46:

Original not seen.

Inhibition and tumor and miang cancer of Res. 39:

8-ethoxy­in the

279.