jason h.t. bates phd, dsc molecular physiology ...presdent/jason bates cv 05-23-14.pdf ·...

CURRICULUM VITAE

JASON H.T. BATES PhD, DSc

Professor

Departments of Medicine and

Molecular Physiology & Biophysics

University of Vermont

Burlington, VT, U.S.A.

May 2014

1

CONTENTS PAGE

Curriculum Vitae

Personal Data 2

Degrees 2

Scholarships and Awards 2

Post-Doctoral Training 3

Academic Appointments 3

Society Memberships 4

Scientific Productivity

Citation History 5

Refereed Journal Papers 5

Conference Papers 21

Books 23

Book Chapters 24

Invited Reviews and Editorials 26

Abstracts and Conference Presentations 28

Patents 56

Invited Addresses 57

Grants

Salary Support for J.H.T. Bates 65

Salary Support for Personnel working under J.H.T. Bates 65

Operating Grants 66

Major Equipment Grants 67

Operating Grants from Internal Agencies 67

Research Contracts 68

Teaching

Courses taught at McGill University and the University of Vermont 69

Supervision of Post-Doctoral Fellows 70

Supervision of Graduate Students 73

Supervision of Undergraduate Students 76

Services to the University and Scientific Community

University Committees 78

Peer Reviewing 79

Technology Transfer 79

2

PERSONAL DATA

Born 1956, England

Naturalized US citizen

Married, 3 children

Work address: University of Vermont College of Medicine

149 Beaumont Avenue

Burlington

Vermont, 05405-0075

tel: (802) 656-8912; fax: (802) 656-8926

email: [email protected]

DEGREES

B.Sc. (First-class Honours) PHYSICS, Canterbury University, Christchurch, New Zealand, 1978. Senior

project: "A study of buoyant wall attachment jets with respect to certain physical parameters".

(Honours III Physics project report no. 77-1, Canterbury University, Christchurch, New Zealand,

1977.)

Ph.D. MEDICINE, Otago University, Dunedin, New Zealand, 1981. (Thesis: Applications of Modelling and

Image Processing in Medicine)

D.Sc. Canterbury University, Christchurch, New Zealand, 1994.

SCHOLARSHIPS AND AWARDS

1975-77 New Zealand University Grants Committee Junior Scholarship.

1975-77 BP(NZ) Ltd. Undergraduate Bursary.

1977 New Zealand University Grants Committee Senior Scholarship.

1978-80 New Zealand University Grants Committee Postgraduate Scholarship.

Kidson Scholarship.

1981 New Zealand Medical Research Council Post-Doctoral Fellowship.

1983 Royal Society of New Zealand Young Scientist Award

1986-91 Canadian Medical Research Council Scholarship.

1991-94 Chercheur Boursier "Senior 1" of the Fonds de la Recherche en Sante du Quebec.

1994-97 Chercheur Boursier "Senior 2" of the Fonds de la Recherche en Sante du Quebec.

2002 Elected Fellow of the American Institute of Medical and Biological Engineering

2004 Elected Senior Member of Institute of Electrical and Electronic Engineers

2005, 2006 Star Reviewer for the Journal of Applied Physiology (one of 3 selected from 104 Editorial

Board members)

2008 - 2012 Member of Faculty of 1000, Biology

2011 Christie Lecturer, Meakins-Christie Laboratories, McGill University, Montreal

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2012 Invited keynote speaker, 40th Hakone Symposium on Respiration, Shiga, Japan

2013 IEEE Green Mountain Section, 2013 Faculty of the Year Award

POST-DOCTORAL TRAINING

Apr 1981-Mar 1982 Post-doctoral Fellow (funded by the Medical Research Council of New Zealand),

Department of Medicine, Christchurch Clinical School of Medicine, Christchurch,

New Zealand. Supervisor: Prof. D.W. Beaven.

Apr 1982-Jul 1983 Scientific Officer, Department of Medicine, Christchurch Clinical School of

Medicine, Christchurch, New Zealand.

Aug 1983-Jun 1986 Research Fellow, Meakins-Christie Laboratories, McGill University, Montreal,

Quebec, Canada. Supervisor: Prof. J. Milic-Emili.

ACADEMIC APPOINTMENTS

Jul 1986-Jun 1991 Assistant Professor, Department of Medicine, University, Montreal, Quebec, Canada.

Jul 1986-Jul 1999 Research Director, Meakins-Christie Laboratories, McGill University, Montreal,

Quebec, Canada.

Jul 1986-Jan 1988 Associate Member, Biomedical Engineering Unit, McGill University, Montreal,

Quebec, Canada.

Aug 1986-Jul 1999 Medical Scientist, Department of Medicine (Respiratory Division), Royal Victoria

Hospital, Montreal, Quebec, Canada.

Feb 1988-June 1991 Assistant Professor, Department of Biomedical Engineering (joint appointment with

Department of Medicine), McGill University, Montreal, Quebec, Canada.

Sep 1988-Jul 1999 Member, Division of Experimental Medicine, Department of Medicine, McGill

University, Montreal, Quebec, Canada.

Jan 1989-Jul 1999 Medical Scientist, Montreal Chest Hospital, Montreal Quebec, Canada.

Nov 1989-Jul 1999 Associate Member, Department of Physiology, McGill University, Montreal, Quebec,

Canada.

Jul 1991-Dec 1998 Associate Professor, Departments of Medicine and Biomedical Engineering (joint

appointment with tenure), McGill University, Montreal, Quebec, Canada.

Sep 1992-Jul 1999 Associate Member, Department of Electrical Engineering, McGill University,

Montreal, Quebec, Canada.

Jan 1995-July 1998 Associate Director, Meakins-Christie Laboratories, McGill University, Montreal,

Quebec, Canada.

Jan 1999-Jul 1999 Professor, Departments Medicine and Biomedical Engineering, McGill University,


Aug 1999-Sept 2007 Research Professor, Departments of Medicine and Molecular Physiology and

Biophysics, University of Vermont, Burlington, VT, U.S.A.

Aug 1999-Present Member of the Pulmonary/Critical Care Division, Department of Medicine,

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University of Vermont and Fletcher Allen Health Care, Burlington, VT, U.S.A.

Aug 1999-Present Adjunct Professor, Department of Medicine-Royal Victoria Hospital, McGill

University, Montreal, Quebec, Canada.

Aug 1999-2011 Adjunct Professor, Department of Biomedical Engineering, McGill University,


May 2005-Present Member of the Graduate Faculty, University of Vermont.

Sept 2007-Present Professor with tenure, Department of Medicine, University of Vermont, Burlington,

VT, U.S.A.

Feb 2010-July 2014 Interim Director, School of Engineering, University of Vermont, Burlington, VT,

U.S.A.

SOCIETY MEMBERSHIPS

I.E.E.E. Biomedical Engineering Society

American Physiological Society.

Biomedical Engineering Society

American Thoracic Society

American Institute of Medical and Biological Engineering

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SCIENTIFIC PRODUCTIVITY

Citation history from Google Scholar 04-17-14:

All Since 2009

Citations 9745 4195

h-index 56 35

i10-index 175 110

A) Journal Papers

A-1) "57

Fe Mossbauer spectroscopy and non-stoichiometry in the marchasite structure compound FeTe2".

J.B. Ward, V.H. McCann, M.P.L. Quin and J.H.T. Bates. Journal of Physics C: Solid State Physics.

11: 377-385, 1978.

A-2) "Estimation of cardiac output from measurements of expired gas concentrations". A.E. McKinnon,

C.G. Male and J.H.T. Bates. Australian Physical & Engineering Sciences in Medicine. 3: 83-88, 1980.

A-3) "Increasing the analysis rate of automatic analysers by subtractively correcting for specimen

interaction". J.H.T. Bates, T.A. Walmsley and A.E. McKinnon. Journal of Automatic Chemistry. 3:

134-137, 1981.

A-4) "The extent of reflux of unconjugated 14

D-cholic acid from the liver in subjects with normal liver

function". D.M. Collins, J.H.T. Bates, A.H. Maslowski, A.E. McKinnon and C.B. Campbell.

Australian Journal of Experimental Biology and Medical Science. 59: 779-790, 1981.

A-5) "Pulmonary capillary blood flow estimation by computer modelling of physiologic gases I. The

viability of a single breath method". J.H.T. Bates and A.E. McKinnon, Clinical Physics and

Physiological Measurement. 3: 31-43, 1982.

A-6) "Pulmonary capillary blood flow estimation by computer modelling of physiologic gases II. The

viability of a multiple breath method". J.H.T. Bates and A.E. McKinnon. Clinical Physics and

Physiological Measurement. 3: 45-55, 1982.

A-7) "Subtractive image restoration. I: General theory". J.H.T. Bates, A.E. McKinnon and R.H.T. Bates.

Optik. 61: 349-364, 1982.

A-8) "Subtractive image restoration. II: Comparison with multiplicative deconvolution". J.H.T. Bates, A.E.

McKinnon and R.H.T. Bates. Optik. 62: 1-14, 1982.

A-9) "Subtractive image restoration. III: Some practical applications". J.H.T. Bates, W.R. Fright, R.P.

Millane, A.D. Seagar, G.T.H. Bates, W.A. Norton, A.E. McKinnon and R.H.T. Bates. Optik. 62:

333-346, 1982.

A-10) "Correction for the dynamic response of a respiratory mass spectrometer". J.H.T. Bates, G.K. Prisk,

T.E. Tanner and A.E. McKinnon. Journal of Applied Physiology. 55: 1015-1022, 1983.

A-11) "Deconvolution in the study of lipoprotein metabolism". J.H.T. Bates and E.D. Janus. Australasian

Physical and Engineering Sciences in Medicine. 6: 174-178, 1983.

A-12) "Characterising and correcting for the dynamic response of a bag-in-box system". J.H.T. Bates, G.K.

Prisk, T.E. Tanner and A.E. McKinnon. Journal of Applied Physiology. 56: 254-258, 1984.

A-13) "Wiener filtering and cleaning in a general image processing context". J.H.T. Bates, W.R. Fright and

R.H.T. Bates. Monthly Notices of The Royal Astronomical Society. 211: 1-14, 1984.

http://scholar.google.com/citations?user=DHivHM8AAAAJ&hl=en&oi=ao



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A-14) "Effect of mechanical loading on displacements of chest wall during breathing in humans". P.M.

Mengeot, J.H.T. Bates and J.G. Martin. Journal of Applied Physiology. 58: 477-484, 1985.

A-15) "A polynomial method for fitting continuous distributions of exponentials with positivity constraint".

J.H.T. Bates. I.E.E.E. Transactions on Biomedical Engineering. 32: 478-484, 1985.

A-16) "Analysis of the behavior of the respiratory system with constant inspiratory flow". J.H.T. Bates, A.

Rossi and J. Milic-Emili. Journal of Applied Physiology. 58: 1840-1848, 1985.

A-17) "Volume-time profile during relaxed expiration in the normal dog". J.H.T. Bates, M. Decramer, D.

Chartrand, W.A. Zin, A. Boddener and J. Milic-Emili. Journal of Applied Physiology. 59: 732-737,

1985.

A-18) "Effects of thermal adaptation at 40oC on membrane viscosity and the sodium-potassium pump in

chinese hampster ovary cells". D.A. Bates, C. LeGrimellec, J.H.T. Bates, A. Loutfi and W.J.

Mackillop. Cancer Research. 45: 4895-4899, 1985.

A-19) "The minimization of muscular energy expenditure during inspiration in linear models of the

respiratory system". J.H.T. Bates. Biological Cybernetics. 54: 195-200, 1986.

A-20) "Respiratory resistance with histamine challenge by single-breath and forced oscillation methods".

J.H.T. Bates, M. Decramer, W.A. Zin, A. Harf, J. Milic-Emili and H.K. Chang. Journal of Applied

Physiology. 61: 873-880, 1986.

A-21) "A model-free way of representing hyperthermia cell survival data". J.H.T. Bates, E. Przybytkowski,

D.A. Bates, and W.J. Mackillop. Radiation Research. 107: 307-316, 1986.

A-22) "Thermal adatation in CHO cells at 40oC: The influence of growth conditions and the role of heat

shock proteins". E. Przybytkowski, J.H.T. Bates, D.A. Bates, and W.J. Mackillop. Radiation Research.

107: 317-331, 1986.

A-23) "Methacholine-induced airway reactivity of inbred rats". C.G. Wang, G. DiMaria, J.H.T. Bates, R.D.

Guttmann, and J.G. Martin. Journal of Applied Physiology. vol 61: 2180-2185, 1986.

A-24) "Un nuovo metodo di studio della meccanica respiratoria in pazienti con insufficienza respiratoria

acuta durante ventilazione meccanica". A. Rossi, S.B. Gottfried, J.H.T. Bates, L. Zocchi, A. Grassino

and J. Milic-Emili. Medicina Toracica. 8: 219-224, 1986.

A-25) "Frequency-dependent effects of hypercapnia on respiratory mechanics of cats". P.D. Sly, J.H.T.

Bates, T. Kochi, S. Okubo and J. Milic-Emili. Journal of Applied Physiology. 62: 444-450, 1987.

A-26) "General method for describing and extrapolating monotonic transients and its application to

respiratory mechanics". J.H.T. Bates, P.D. Sly and S. Okubo. Medical & Biological Engineering &

Computing. 25: 131-135, 1987.

A-27) "Effect of valve closure time on the determination of respiratory resistance by flow interruption".

J.H.T. Bates, I.W. Hunter, P.D. Sly, S. Okubo, S. Filiatrault and J. Milic-Emili. Medical & Biological

Engineering & Computing. 25: 136-140, 1987.

A-28) "On the difficulties of fitting the double Michaelis-Menton equation to kinetic data". J.H.T. Bates,

D.A. Bates and W.MacKillop. Journal of Theoretical Biology. 125: 237-241, 1987.

A-29) "Partitioning of airway responses to inhaled methacholine in the rat". G.U. DiMaria, C.G. Wang,

J.H.T. Bates, R. Guttmann and J.G. Martin. Journal of Applied Physiology. 62: 1317-1323, 1987.

A-30) "Measurement of respiratory mechanics using the Siemens servo ventilator 900C". P.D. Sly, J.H.T.

Bates and J. Milic-Emili. Pediatric Pulmonology. 3: 400-405, 1987.

7

A-31) "The effect of a proximal compliance on interrupter measurements of resistance". J.H.T. Bates, P.D.

Sly, T. Kochi and J.G. Martin. Respiration Physiology. 70: 301-312, 1987.

A-32) "Effect of lung volume on interrupter resistance in cats challenged with methacholine". P.D. Sly, K.A.

Brown, J.H.T. Bates, P.T. Macklem, J. Milic-Emili and J.G. Martin. Journal of Applied Physiology.

64: 360-366, 1988.

A-33) "A theoretical analysis of the interrupter technique for measuring respiratory mechanics". J.H.T. Bates,

P. Baconnier, and J. Milic-Emili. Journal of Applied Physiology. 64: 2204-2214, 1988.

A-34) "Interrupter resistance elucidated by alveolar pressure measurement in open-chest normal dogs".

J.H.T. Bates, M.S. Ludwig, P.D. Sly, K. Brown, J.G. Martin and J.J. Fredberg. Journal of Applied

Physiology. 65: 408-414, 1988.

A-35) "Noninvasive determination of respiratory mechanics during mechanical ventilation in neonates: A

review of current and future techniques". P.D. Sly, K.A. Brown, J.H.T. Bates, S. Spier and J. Milic-

Emili. Pediatric Pulmonology. 4: 39-47, 1988.

A-36) "Computer analysis of physical factors affecting the use of the interrupter technique in infants". P.D.

Sly and J.H.T. Bates. Pediatric Pulmonology. 4: 219-224, 1988.

A-37) "A subtractive method for decomposing muscle tension into individual twitches". J.H.T. Bates, S.

Janssens, T.X. Jiang, I.W. Hunter and M. Decramer. Computers and Biomedical Research. 21:

570-578, 1988.

A-38) "Evaluation of the flow-volume loop as an intra-operative monitor of respiratory mechanics in

infants". K. Brown, P.D. Sly, J. Milic-Emili and J.H.T. Bates. Pediatric Pulmonology. 6: 8-13, 1989.

A-39) "Measurement of alveolar pressure in closed-chest dogs during flow interruption". J.H.T. Bates, T.

Abe, P.V. Romero, and J. Sato. Journal of Applied Physiology. 67: 488-492, 1989.

A-40) "Correcting for the thermodynamic characteristics of a body plethysmograph". J.H.T. Bates. Annals of

Biomedical Engineering. 17: 647-655, 1989.

A-41) "A Comparison of the dose-response behaviour of canine airways and parenchyma". M.S. Ludwig,

P.V. Romero and J.H.T. Bates. Journal of Applied Physiology. 67: 1220-1225, 1989.

A-42) "Viscoelastic behaviour of lung and chest wall in dogs determined by flow interruption". T.

Similowski, P. Levy, C. Corbeil, M. Albala, R. Pariente, J.-P. Derenne, J.H.T. Bates, B. Jonson and J.

Milic-Emili. Journal of Applied Physiology. 67: 2219-2229, 1989.

A-43) "Respiratory mechanics determined by flow interruption during passive expiration in cats". T. Kochi,

J.H.T. Bates, S. Okubo, E.S. Petersen and J. Milic-Emili. Respiration Physiology. 78: 243-252, 1989.

A-44) "Respiratory mechanics in the normal dog determined by expiratory flow interruption". J.H.T. Bates,

K.A. Brown and T. Kochi. Journal of Applied Physiology. 67: 2276-2285, 1989.

A-45) "The low-frequency dependence of respiratory system resistance and elastance in normal dogs". J.H.T.

Bates, F. Shardonofsky and D.E. Stewart. Respiration Physiology. 78: 369-382, 1989.

A-46) "Interpretation of interrupter resistance after histamine-induced constriction in the dog". M.S. Ludwig,

P.V. Romero, P.D. Sly, J.J. Fredberg and J.H.T. Bates. Journal of Applied Physiology. 68: 1651-1656,

1990.

A-47) "Effect of the thermodynamics of an infant plethysmograph on the measurement of thoracic gas

volume". P.D. Sly, C. Lanteri and J.H.T. Bates. Pediatric Pulmonology. 8: 203-208, 1990.

A-48) "Quasi-static pressure-volume hysteresis in the canine respiratory system in vivo". F.R. Shardonofsky,

J. Sato and J.H.T. Bates. Journal of Applied Physiology. 68: 2230-2236, 1990.

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A-49) "Respiratory mechanics in anesthesia". J. Milic-Emili, F.M. Robatto and J.H.T. Bates. British Journal

of Anesthesia. 65: 4-12, 1990.

A-50) "A theoretical study of the effect of airway smooth muscle orientation on bronchoconstriction". J.H.T.

Bates and J.G. Martin. Journal of Applied Physiology. 69: 995-1001, 1990.

A-51) "Late response of the upper airway of the rat to inhaled antigen." L.J. Xu, D.H. Eidelman, J.H.T. Bates

and J.G. Martin. Journal of Applied Physiology. 69: 1360-1365, 1990.

A-52) "Exponential fitting of pressure volume curves: confidence limits and sensitivity to noise." D.H.

Eidelman, H. Ghezzo and J.H.T. Bates, Journal of Applied Physiology. 69: 1538-1541, 1990.

A-53) "High-frequency characteristics of respiratory mechanics determined by flow interruption". P.V.

Romero, J. Sato, F. Shardonofsky and J.H.T. Bates. Journal of Applied Physiology. 69: 1682-1688,

1990.

A-54) "Two-compartment modelling of respiratory system mechanics at low frequencies: gas redistribution

or tissue rheology?" T. Similowski and J.H.T. Bates. The European Respiratory Journal. 4: 353-358,

1991.

A-55) "Low-frequency respiratory system resistance in the normal dog during mechanical ventilation." J.

Sato, B.L.K. Davey, F. Shardonofsky and J.H.T. Bates. Journal of Applied Physiology. 70:

1536-1543, 1991.

A-56) "Gas physical properties and respiratory system resistance measured by flow interruption". T. Abe, J.

Sato, P. Romero and J.H.T. Bates. Respiration Physiology. 84: 159-170, 1991.

A-57) "Histamine-induced constriction of canine peripheral lung: an airways or tissue response?" M.S.

Ludwig, F.M. Robatto, P.D. Sly, M. Browman, J.H.T. Bates and P.V. Romero. Journal of Applied

Physiology. 71: 287-293, 1991.

A-58) "A nonlinear viscoelastic model of lung tissue mechanics." B. Suki and J.H.T. Bates. Journal of

Applied Physiology. 71: 826-833, 1991.

A-59) "Estimation of time-varying respiratory mechanical parameters by recursive least squares." A.-M.

Lauzon and J.H.T. Bates. Journal of Applied Physiology. 71: 1159-1165, 1991.

A-60) "Deconvolution of tracer and dilution data using the Wiener filter." J.H.T. Bates. I.E.E.E. Transactions

on Biomedical Engineering. 38: 1262-1266, 1991.

A-61) "Partitioning of respiratory mechanics in mechanically ventilated patients." G. Polese, A. Rossi, L.

Appendini, G. Brandi, J.H.T. Bates and R. Brandolese. Journal of Applied Physiology. 71: 2425-

2433, 1991.

A-62) "The flow interruption technique for measuring respiratory resistance." J.H.T. Bates and J. Milic-

Emili. Journal of Critical Care. 6: 227-238, 1991.

A-63) "Lung mechanics - the inverse problem." J.H.T. Bates. Australasian Physical & Engineering Sciences

in Medicine. 14: 197-203, 1991.

A-64) "A comparison of interrupter and forced oscillation measurements of respiratory system resistance in

the dog." J.H.T. Bates, B. Daroczy and Z. Hantos. Journal of Applied Physiology. 72: 46-52, 1992.

A-65) "Factors affecting the accuracy of esophageal balloon measurement of pleural pressure in dogs." G.

Dechman, J. Sato and J.H.T. Bates. Journal of Applied Physiology. 72: 383-388, 1992.

A-66) "A non-statistical approach to estimating confidence intervals about model parameters: application to

respiratory mechanics." J.H.T. Bates and A.-M. Lauzon. I.E.E.E. Transactions on Biomedical

Engineering. 39: 94-100, 1992.

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A-67) "Correcting for the Bernoulli effect in lateral pressure measurements." J.H.T. Bates, P.D. Sly, J. Sato,

B.L.K. Davey and B. Suki. Pediatric Pulmonology. 12: 251-256, 1992.

A-68) "Low-frequency pulmonary impedance in rabbits and its response to inhaled methacholine." R.

Tepper, J. Sato, B. Suki, J.G. Martin and J.H.T. Bates. Journal of Applied Physiology. 73: 290-295,

1992.

A-69) "Time course of respiratory mechanics during histamine challenge in the dog." A.-M. Lauzon, G.

Dechman and J.H.T. Bates. Journal of Applied Physiology. 73: 2643-2647, 1992.

A-70) "Effect of pleural effusion on respiratory mechanics, and the influence of deep inflation, in dogs." G.

Dechman, J. Sato and J.H.T. Bates. European Respiratory Journal. 6: 219-224, 1993

A-71) "Regional lung impedance from forced oscillations through alveolar capsules." B.L.K. Davey and

J.H.T. Bates. Respiration Physiology. 91: 165-182, 1993.

A-72) "Effect of methacholine on low-frequency mechanics of canine airways and lung tissue." J. Sato, B.

Suki, B.L.K. Davey and J.H.T. Bates. Journal of Applied Physiology. 75: 55-62, 1993.

A-73) "Acute pulmonary response to intravenous histamine at fixed lung volume in dogs". J.H.T. Bates and

R. Peslin. Journal of Applied Physiology. 75: 405-411, 1993.

A-74) "Understanding lung tissue mechanics in terms of mathematical models." J.H.T. Bates. Monaldi

Archives for Chest Disease. 48: 134-139, 1993.

A-75) "Influence of the viscoelastic properies of the respiratory system on the energetically optimum

breathing frequency." J.H.T. Bates and J. Milic-Emili. Annals of Biomedical Engineering. 21: 489-

499, 1993.

A-76) "Airway and tissue impedances of canine lungs after step volume changes." J.H.T. Bates, F.A.

Donoso and R. Peslin. Journal of Applied Physiology. 75: 1460-1466, 1993.

A-77) "Stochastic model of the pulmonary airway tree and its implications for bronchial responsiveness."

J.H.T. Bates. Journal of Applied Physiology. 75: 2493-2499, 1993.

A-78) "Breathing patterns in infants and children under halothane anesthesia: effect of dose and CO2." O.

Reich, K. Brown and J.H.T. Bates. Journal of Applied Physiology. 76: 79-85, 1994.

A-79) "Temporal dynamics of pulmonary response to intravenous histamine in dogs: effects of dose and lung

volume." J.H.T. Bates, A.-M. Lauzon, G.S. Dechman, G.N. Maksym and T.F. Schuessler. Journal of


A-80) "Mechanical behaviour of the canine respiratory system at very low lung volumes." G. Dechman, A.-

M. Lauzon and J.H.T. Bates. Respiration Physiology. 95: 119-129, 1994.

A-81) "Oscillatory pressure-flow relationships of canine airways: a steady-state model for different gases." J.

Sato, B.L.K. Davey, B. Suki and J.H.T. Bates. Journal of Applied Physiology. 76: 923-932, 1994.

A-82) "Assessment of acute pleural effusion in dogs by computed tomography." G. Dechman, M. Mishima

and J.H.T. Bates. Journal of Applied Physiology. 76: 1993-1998, 1994.

A-83) "Serial distribution of airway mechanical properties in dogs: effects of histamine." R.H. Habib, B.

Suki, J.H.T. Bates, and A.C. Jackson. Journal of Applied Physiology. 77: 554-566, 1994.

A-84) "Acute pulmonary response to intravenous histamine using forced oscillations through alveolar

capsules in dogs." M. Mishima, Z. Balassy and J.H.T. Bates. Journal of Applied Physiology. 77:

2140-2148, 1994.

A-85) "Lung tissue rheology and 1/f noise". J.H.T. Bates, G.N. Maksym, D. Navajas and B. Suki. Annals of


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A-86) "Altered mechanical properties of lung parenchyma in postobstructive pulmonary vasculopathy."

S.M. Kelly, J.H.T. Bates and R.P. Michel. Journal of Applied Physiology. 77: 2543-2551, 1994.

A-87) "Time course of histamine-induced bronchoconstriction and its adrenergic and H2 modulation." A.-M.

Lauzon, G. Dechman, J.G. Martin and J.H.T. Bates. Respiration Physiology. 99: 127-138, 1995.

A-88) "On the use of the alveolar capsule technique to study bronchoconstriction". A.-M. Lauzon, G.

Dechman and J.H.T. Bates. Respiration Physiology. 99: 139-146, 1995.

A-89) "Changes in regional lung impedance following intravenous histamine bolus in dogs: effects of lung

volume." Z. Balassy, M. Mishima and J.H.T. Bates. Journal of Applied Physiology. 78: 875-880,

1995.

A-90) "Respiratory mechanics and gas exchange in postobstructive pulmonary vasculopathy." S.M. Kelly,

J.H.T. Bates and R.P. Michel. European Respiratory Journal. 8: 202-208, 1995.

A-91) "Bronchoconstriction and broken symmetry." J.H.T. Bates. Comments on Theoretical Biology. 3: 397-

415, 1995.

A-92) "A computer-controlled research ventilator for small animals: design and evaluation." T.F. Schuessler

and J.H.T. Bates. I.E.E.E. Transactions on Biomedical Engineering. 42: 860-866, 1995.

A-93) "The effect of changing end-expiratory pressure on respiratory system mechanics in open- and closed-

chested anesthetized, paralyzed patients." G.S. Dechman, D.A. Chartrand, R.P. Ruiz-Neto and J.H.T.

Bates. Anesthesia & Analgesia. 81: 279-286, 1995.

A-94) "Dynamic viscoelastic nonlinearity of lung parenchymal tissue." D. Navajas, G.N. Maksym and J.H.T.

Bates. Journal of Applied Physiology. 79: 348-356, 1995.

A-95) "A model of transient oscillatory pressure-flow relationships of canine airways." B. Suki, B.L.K.

Davey, J. Sato and J.H.T. Bates. Annals of Biomedical Engineering. 23: 682-690, 1995.

A-96) "Measuring the mechanical properties of the lung in vivo with spatial resolution at the acinar level."

J.H.T. Bates, M. Mishima and Z. Balassy. Physiological Measurement. 16: 151-159, 1995.

A-97) "Ventilatory depression by halothane in infants and children." K.A. Brown, O. Reich and J.H.T. Bates.

Canadian Journal of Anesthesiology. 42: 588-596, 1995.

A-98) "Ventilatory response to cholecystokinin tetrapeptide in anaesthetized dogs." J.H.T. Bates and J.

Bradwejn. NeuroReport. 6: 2513-2517, 1995.

A-99) "The effect of delay in treatment on local control by radiotherapy." W.J. Mackillop, J.H.T. Bates, B.

O'Sullivan and H.R. Withers. International Journal of Radiation Oncology Biology Physics. 34: 243-

250, 1996.

A-100) "Temporal response of lung impedance after i.v. oleic acid in dogs." M. Mishima, Z. Balassy and

J.H.T. Bates. Respiration Physiology. 103: 177-185, 1996.

A-101) "Assessment of local lung impedance by the alveolar capsule oscillator in dogs: a model analysis." M.

Mishima, Z. Balassy and J.H.T. Bates. Journal of Applied Physiology. 80: 1165-1172, 1996.

A-102) "The multilevel mechanical behaviour of the lung during induced bronchoconstriction." J.H.T. Bates.

Australasian Physical & Engineering Sciences in Medicine. 19: 35-45, 1996.

A-103) "A distributed nonlinear model of lung tissue elasticity." G.N. Maksym and J.H.T. Bates. Journal of


A-104) "Temporal dynamics of acute isovolume bronchoconstriction in the rat." J.H.T. Bates, T.F. Schuessler,

C. Dolman and D.H. Eidelman. Journal of Applied Physiology. 82: 55-62, 1997.

11

A-105) "Effect of stochastic heterogeneity on lung impedance during acute bronchoconstriction: a model

analysis." C.W. Thorpe and J.H.T. Bates. Journal of Applied Physiology. 82: 1616-1625, 1997.

A-106) "A model of the spontaneously breathing patient: applications to intrinsic PEEP and work of

breathing." T.F. Schuessler, S.B. Gottfried and J.H.T. Bates. Journal of Applied Physiology. 82: 1694

- 1703, 1997.

A-107) “Monitoring changes in lung air and liquid volumes with electrical impedance tomography.” A. Adler,

R. Amyot, R. Guardo, J.H.T. Bates and Y. Berthiaume. Journal of Applied Physiology. 83: 1762-

1767, 1997.

A-108) “Nonparametric block structured modeling of rat lung mechanics.” G.N. Maksym, and J.H.T. Bates.

Annals of Biomedical Engineering. 25: 1000-1008, 1997.

A-109) “Nonparametric block structured modeling of lung tissue strip mechanics.” G.N. Maksym, R.E.

Kearney and J.H.T. Bates. Annals of Biomedical Engineering. 26: 242-252, 1998.

A-110) "Current patterns and electrode types for single-source electrical impedance tomography of the

thorax." T.F. Schuessler and J.H.T. Bates. Annals of Biomedical Engineering. 26: 253-259, 1998.

A-111) “An adaptive filter to reduce cardiogenic oscillations on esophageal pressure signals.” T.F. Schuessler,

S.B. Gottfried, P. Goldberg, R.E. Kearney and J.H.T. Bates.” Annals of Biomedical Engineering. 26:

260-267, 1998.

A-112) “Isovolume bronchoconstriction by vagal stimulation in dogs: effects of lung inflation pressure.” N.

Shinozuka, T. Nemoto and J.H.T. Bates. Respiration Physiology. 111: 79-88, 1998.

A-113) “Electrical impedance tomography can monitor dynamic hyperinflation in dogs.” A. Adler, N.

Shinozuka, Y. Berthiaume, R. Guardo, and J.H.T. Bates. Journal of Applied Physiology. 84: 726-732,

1998.

A-114) “A micromechanical model of lung tissue rheology”. J.H.T. Bates. Annals of Biomedical

Engineering. 26: 679-687, 1998.

A-115) “Airway-parenchymal interdependence after airway contraction in rat lung explants.” A. Adler, E.A.

Cowley, J.H.T. Bates and D.H. Eidelman. Journal of Applied Physiology. 85: 231-237, 1998.

A-116) “Effects of cholecystokinin tetrapeptide on respiratory function in healthy volunteers.” J. Bradwejn, J-

M. LeGrand, D. Koszycki, J.H.T. Bates, and M. Bourin. American Journal of Psychiatry. 155: 280-

282, 1998.

A-117) “Force heterogeneity in a two-dimensional network model of lung tissue elasticity.” G.N. Maksym, J.J.

Fredberg and J.H.T. Bates. Journal of Applied Physiology. 85: 1223-1229, 1998.

A-118) “Effect of time-varying load on degree of bronchoconstriction in the dog.” N. Shinozuka, J.-P. Lavoie,

J.G. Martin and J.H.T. Bates. Journal of Applied Physiology. 85: 1464-1470, 1998.

A-119) “Effects of lung volume on lung and chest wall mechanics in rats.” T. Hirai, K.A. McKeown, R.F.M.

Gomes and J.H.T. Bates. Journal of Applied Physiology. 86: 16-21, 1999.

A-120) “Estimating respiratory mechanics in the presence of flow limitation.” E. Bijaoui, S.A. Tuck, J.E.

Remmers, and J.H.T. Bates. Journal of Applied Physiology. 86: 418-426, 1999

A-121) “Breathing responses to small inspiratory threshold loads inhumans. S. Yan and J.H.T. Bates. Journal

of Applied Physiology. 86: 874-880, 1999

A-122) “Automatic control of pressure support mechanical ventilation using fuzzy logic.” T. Nemoto, G.E.

Hatzakis, C.W. Thorpe, R. Olivenstein, S. Dial and J.H.T. Bates. American Journal of Respiratory and

Critical Care Medicine. 160: 550-556, 1999.

12

A-123) “Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects

and patients with chronic obstructive pulmonary disease.” M. Mishima, T. Hirai, H. Itoh, Y. Nakano,

H. Sakai, S. Muro, K. Nishimura, Y. Oku, K. Chin, M. Ohi, T. Nakamura, J.H.T. Bates, A.M. Alencar

and B. Suki. Proceedings of the National Academy of Sciences USA. 96: 8829-8834, 1999.

A-124) “Lung micromechanics.” J.H.T. Bates. European Respiratory Monograph. 12: 157-170, 1999

A-125) “Bronchial responsiveness among inbred mouse strains: role of airway smooth muscle shortening

velocity.” A. Duguet, K. Biyah, E. Minshall, R. Gomes, C.-G. Wang, M. Taoudi-Benchekroun, J.H.T.

Bates and D.H. Eidelman. American Journal of Respiratory and Critical Care Medicine. 161: 839-848,

2000.

A-126) “A micromechanical model of airway-parenchymal interdependence.” A. Adler and J.H.T. Bates.


A-127) “Effects of cool, dry air stimulation on peripheral lung mechanics in asthma.” D.A. Kaminsky, J.H.T.

Bates and C.G. Irvin. American Journal of Respiratory and Critical Care Medicine. 162: 179-186,

2000.

A-128) “Comparative respiratory system mechanics in rodents.” R.F.M. Gomes, X. Shen, R. Ramchandani,

R.S. Tepper and J.H.T. Bates. Journal of Applied Physiology. 89: 908-916, 2000.

A-129) “Kinetics of respiratory system elastance after airway challenge in dogs.” A.-M. Lauzon and J.H.T.


A-130) “Specifications for equipment used for infant pulmonary function testing.” U. Frey, J. Stocks, A.

Coates, P. Sly and J.H.T. Bates. European Respiratory Journal. 16: 731-740, 2000.

A-131) “Specifications for signal processing and data handling used for infant pulmonary function testing.” U.

Frey, J. Stocks, P. Sly and J.H.T. Bates. European Respiratory Journal. 16: 1016-1022, 2000

A-132) “Tidal breath analysis for infant pulmonary function testing.” J.H.T. Bates, G. Schmalisch, D. Filbrun

and J. Stocks. European Respiratory Journal. 16: 1180-1192, 2000.

A-133) “Airway branching morphology of mature and immature rabbit lungs.” R. Ramchandani, J.H.T. Bates,

X. Shen, B. Suki and R.S. Tepper. Journal of Applied Physiology. 90:1584-1592, 2001.

A-134) “Respiratory mechanics and lung development in the rat from early age to adulthood.” R.F.M. Gomes,

F. Shardonofsky, D.H. Eidelman, and J.H.T. Bates. Journal of Applied Physiology. 90: 1631-1638,

2001.

A-135) “Mechanical impedance of the lung determined from cardiogenic oscillations.” E. Bijaoui, P.F.

Baconnier, and J.H.T. Bates. Journal of Applied Physiology. 91: 859-865, 2001.

A-136) “Fuzzy logic and mechanical ventilation.” J.H.T. Bates, G.E. Hatzakis and R. Olivenstein. Respiratory

Care Clinics of North America. 9: 363-377, 2001.

A-137) “Effects of deep inspiration on bronchoconstriction in the rat.” T. Hirai and J.H.T. Bates. Respiration

Physiology. 127: 201-215, 2001.

A-138) “Automated analysis of paradoxical ribcage motion during sleep in infants.” K.A. Brown, R. Platt and

J.H.T. Bates. Pediatric Pulmonology. 33: 38-46, 2002.

A-139) “Nonlinearity of respiratory mechanics during bronchoconstriction in mice with airway inflammation.”

S.Wagers, L.Lundblad, H.T. Moriya, J.H.T. Bates, and C.G. Irvin. Journal of Applied Physiology.

92: 1802-1807, 2002.

A-140) “Mechanical properties of the lung and upper airways in patients with sleep-disordered breathing.”

E.L. Bijaoui, V. Champagne P. F. Baconnie, R. J. Kimoff and J.H.T. Bates. American Journal of

13

Respiratory and Critical Care Medicine. 165: 1055-1061, 2002.

A-141) “Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs. forced oscillations.”

S. Tomioka, J.H.T. Bates and C.G. Irvin. Journal of Applied Physiology. 93: 263-270, 2002.

A-142) “Geometric determinants of airway resistance in two isomorphic rodent species.” R.F.M. Gomes and

J. H.T. Bates. Respiratory Physiology & Neurobiology. 130: 317-325, 2002.

A-143) “Dependence of intrapulmonary pressure amplitudes on respiratory mechanics during high-frequency

oscillatory ventilation in preterm lambs.” J.J. Pillow, P.D. Sly, Z. Hantos and J.H.T. Bates. Pediatric

Research. 52:538-544, 2002.

A-144) “Time dependence of recruitment and derecruitment in the lung: a theoretical model.” Jason H.T.

Bates and Charles G. Irvin. Journal of Applied Physiology. 93: 705-713, 2002.

A-145) “A reevaluation of the validity of unrestrained plethysmography in mice”. L. Lundblad, C.G. Irvin, A.

Adler, and J.H.T. Bates. Journal of Applied Physiology. 93: 1198-1207, 2002.

A-146) “Transient mechanical benefits of a deep inflation in the injured mouse lung.” G. Allen, L.K.A.

Lundblad, P. Parsons, and J.H.T. Bates. Journal of Applied Physiology. 93: 1709-1715, 2002.

A-147) “1-antitrypsin determines the pattern of emphysema and function in tobacco smoke –exposed mice:

parallels with human disease.” Y. Takubo, A. Guerassimov, H. Ghezzo, A. Triantafillopoulos, J.H.T.

Bates, J.R. Hoidal, and M.G. Cosio. American Journal of Respiratory and Critical Care Medicine.

166: 1596-1603, 2002.

A-148) “Measuring lung function in mice: the phenotyping uncertainty principle.” J.H.T. Bates and C.G.

Irvin. Journal of Applied Physiology (Invited Review). 94: 1297-1306, 2003.

A-149) “Nonlinear and frequency dependent mechanical behavior of the mouse respiratory system.” H.T.

Moriya, J.C.T.B. Moraes, and J.H.T. Bates. Annals of Biomedical Engineering. 31: 318-326, 2003.

This paper was listed in the online Virtual Journal of Biological Physics Research at

http://www.vjbio.org/bio/

A-150) “Applying fuzzy logic to medical decision-making in the intensive care unit.” J.H.T. Bates and M.P.

Young. American Journal of Respiratory and Critical Care Medicine (Invited Critical Care

Perspective). 167: 948-952, 2003. This paper was reproduced for LNC Resource. The National Source

for Legal Nurse Consulting. Vol. 2, No. 5, May 2005.

A-151) “Measuring the lung function of the mouse: the challenge of size.” C.G. Irvin and J.H.T. Bates.

Respiratory Research. 4: 2003 (http://respiratory-research.com/content/4/1/4).

A-152) “The conceptual basis of mathematics in cardiology: (I) Algebra, functions and graphs.” J.H.T. Bates

and B.E. Sobel. Coronary Artery Disease. 14: 41-59, 2003.

A-153) “The conceptual basis of mathematics in cardiology: (II) Calculus and differential equations.” J.H.T.

Bates and B.E. Sobel. Coronary Artery Disease. 14: 135-148, 2003.

A-154) “The conceptual basis of mathematics in cardiology: (III) Linear systems theory and integral

transforms.” J.H.T. Bates and B.E. Sobel. Coronary Artery Disease. 14: 185-196, 2003.

A-155) “The conceptual basis of mathematics in cardiology: (IV) Statistics and model fitting.” J.H.T. Bates

and B.E. Sobel. Coronary Artery Disease. 14: 267-277, 2003.

A-156) “Dynamic mechanical consequences of deep inflation in mice depend on type and degree of lung

injury.” G.B. Allen and J.H.T. Bates. Journal of Applied Physiology. 96: 293-300, 2004.

14

A-157) “Time course of airway mechanics of the (+)insert myosin isoform knockout mouse.” S.A. Tuck, K.

Maghni, A. Poirier, G.J. Babu, M. Periasamy, J.H.T. Bates, R. Leguillette, A.-M. Lauzon. American

Journal of Respiratory Cell and Molecular Biology. 30: 326-332, 2004.

A-158) “The allergic mouse model of asthma: normal smooth muscle in an abnormal lung?” S. Wagers,

L.K.A. Lundblad, M. Ekman, C.G. Irvin and J.H.T. Bates. Journal of Applied Physiology. 96: 2019-

2027, 2004.

A-159) “Ventilation of patients with acute lung injury and acute respiratory distress syndrome: Has new

evidence changed clinical practice?.” M.P. Young, H.L. Manning, D.L. Wilson, S.A. Mette, R.R.

Riker, J.C. Leiter, S.K. Liu, J.H.T. Bates, and P.E. Parsons. Critical Care Medicine. 32: 1260-1265,

2004.

A-160) “Extravascular fibrin, plasminogen activator, plasminogen activator inhibitors, and airway

hyperresponsiveness.” S.W. Wagers, R.J. Norton, L.M. Rinaldi, J.H.T. Bates, B.E. Sobel, and C.G.

Irvin. Journal of Clinical Investigation. 114: 104-111, 2004.

A-161) “Thoracic gas volume measurements in paralyzed mice.” L.K.A. Lundblad, J. Thompson-Figueroa, T.

Leclair, C.G. Irvin, and J.H.T. Bates. Annals of Biomedical Engineering. 32: 1420-1427, 2004.

A-162) “The "Goldilocks Effect" in Cystic Fibrosis: Identification of a Lung Phenotype in the cftr

Knockout and Heterozygous Mouse.” J.C. Cohen, L.K.A. Lundblad, J.H.T. Bates, M. Levitzky,

and J.E. Larson. BMC Genetics. 5: 21 (6 pages), 2004.

A-163) “Oscillation mechanics of the human lung periphery in asthma.” D.A. Kaminsky, C.G. Irvin, L.

Lundblad, H.T. Moriya, S. Lang, J. Allen, T. Viola, M. Lynn, and Jason H.T. Bates. Journal of


A-164) “Mechanical properties of mouse distal lung: in vivo vs in vitro comparison.” A. Fust, J.H.T.

Bates, and M.S. Ludwig. Respiratory Physiology & Neurobiology. 143: 77-86, 2004.

A-165) “On the terminology for describing the length-force relationship and its changes in airway smooth

muscle.” T.R. Bai, J.H.T. Bates, V. Brusasco, B. Camoretti-Mercado, P. Chitano, L.H. Deng, M.

Dowell, B. Fabry, L.E. Ford, J.J. Fredberg, W.T. Gerthoffer, S.H. Gilbert, S.J. Gunst, C.M. Hai, A.J.

Halayko, S.J. Hirst, A.L. James, L.J. Janssen, K.A. Jones, G.G. King, O.J. Lakser, R.K. Lambert, A.-

M. Lauzon, K.L. Lutchen, G.N. Maksym, R.A. Meiss, S.M. Mijailovich, H.W. Mitchell, R.W.

Mitchell, W. Mitzner, T.M. Murphy, P.D. Paré, R.R. Schellenberg, C.Y. Seow, G.C. Sieck, P.G.

Smith, A.V. Smolensky, J. Solway, N.L. Stephens, A.G. Stewart, D.D. Tang, and L. Wang. Journal of


A-166) “Peak pressures during manual ventilation.” M. Turki, M.P. Young, S.S. Wagers, and J.H.T. Bates.

Respiratory Care. 50: 340-344, 2005.

A-167) “Tumor necrosis factor- overexpression in lung disease: a single cause behind a complex

phenotype.” L.K.A. Lundblad, J. Thompson-Figueroa, T. Leclair, M.J. Sullivan, M.E. Poynter, C.G.

Irvin, and J.H.T. Bates. American Journal of Respiratory and Critical Care Medicine. 171: 1363-1370,

2005.

A-168) “Pulmonary impedance and alveolar instability during injurious ventilation in rats.” G.B. Allen, L.A.

Pavone, J.D. DiRocco, J.H.T. Bates, and G.F. Nieman. Journal of Applied Physiology. 99: 723-730,

2005.

A-169) “The interface between measurement and modeling of peripheral lung mechanics.” J.H.T. Bates, and

K.R. Lutchen. Respiratory Physiology & Neurobiology. 148: 153-164, 2005.

15

A-170) “Airways hyperresponsiveness induced by cationic proteins in vivo: site of action.” T. Homma, J.H.T.

Bates, and C.G. Irvin,. American Journal of Physiology - Lung Cellular and Molecular Physiology.

289: L413-L418, 2005.

A-171) “Modeling the oscillation dynamics of activated airway smooth muscle strips” J.H.T. Bates, and A.-M.

Lauzon. American Journal of Physiology - Lung Cellular and Molecular Physiology. 289: L849-L855,

2005.

A-172) “Exaggerated airway narrowing in mice treated with intra-tracheal cationic protein.” J.H.T. Bates,

S.S. Wagers, R.J. Norton, L.M. Rinaldi, and C.G. Irvin. Journal of Applied Physiology. 100 : 500-

506, 2006.

A-173) “The estimation of lung mechanics parameters in the presence of pathology: A theoretical analysis.“

J.H.T. Bates and G.B. Allen. Annals of Biomedical Engineering. 34: 384-392, 2006.

A-174) “Choosing the Frequency of Deep Inflation in Mice: Balancing Recruitment against Ventilator-

Induced Lung Injury.” G.B. Allen, B.T. Suratt, L. Rinaldi, J.M. Petty, and J.H.T. Bates. American

Journal of Physiology - Lung Cellular and Molecular Physiology. 291: L710-L717, 2006.

A-175) “Intrinsic and antigen induced airway hyperresponsiveness are the result of diverse physiologic

mechanisms.” S. Wagers, H.C. Haverkamp, J.H.T. Bates, R.J. Norton, J.A. Thompson-Figueroa, M.J.

Sullivan, and C.G. Irvin. Journal of Applied Physiology. 102: 221-230, 2007.

A-176) “Airways hyperresponsiveness in allergically inflamed mice: the role of airway closure.” L.K.A.

Lundblad, J. Thompson-Figueroa, G.B. Allen, L. Rinaldi, C.G. Irvin and J H.T. Bates. American

Journal of Respiratory and Critical Care Medicine. 171: 1363-1370, 2007.

A-177) “Parenchymal tethering, airway wall stiffness, and the dynamics of bronchoconstriction.” J.H.T. Bates

and A.-M. Lauzon. Journal of Applied Physiology. 102: 1912-1920, 2007.

A-178) “Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.” S.S. An.

T.R. Bai, J.H.T. Bates, J.L Black, R.H. Brown, V. Brusasco, P. Chitano, L. Deng, M. Dowell, D.H.

Eidelman, B. Fabry, N.J. Fairbank, L.E. Ford, J.J. Fredberg, W.T. Gerthoffer, S.H. Gilbert, R. Gosens,

S.J. Gunst, A.J. Halayko, R.H. Ingram, C.G. Irvin, A.L. James, L.J. Janssen, G.G. King, D.A. Knight,

A.M. Lauzon, O.J. Lakser, M.S. Ludwig, K.R. Lutchen, G.N. Maksym, J.G. Martin, T. Mauad, B.E.

McParland, S.M. Mijailovich, H.W. Mitchell, R.W. Mitchell, W. Mitzner, T.M. Murphy, P.D. Paré,

R. Pellegrino, M.J. Sanderson, R.R. Schellenberg, C.Y. Seow, P.S.P. Silveira, P.G. Smith, J. Solway,

N.L. Stephens, P.J. Sterk, A.G. Stewart, D.D. Tang, R.S. Tepper, T. Tran, L. Wang. European

Respiratory Journal. 29: 834-860, 2007.

A-179) “A recruitment model of quasi-linear power-law stress adaptation in biological soft tissue.” J.H.T.

Bates. Annals of Biomedical Engineering. 35: 1165-1174, 2007.

A-180) “The response to recruitment worsens with progression of lung injury in a mouse model of acid

aspiration.” G.B. Allen, T. Leclair, M. Cloutier, J. Thompson-Figueroa and J.H.T. Bates. American

Journal of Physiology – Lung, Cell and Molecular Physiology. 292: L1580-L1589, 2007.

A-181) “Linking parenchymal disease progression to changes in lung mechanical function by percolation.”

J.H.T. Bates, G.S. Davis, A. Majumdar, K.J. Butnor and B. Suki. American Journal of Respiratory

and Critical Care Medicine. 176: 617-623, 2007.

A-182) “Bronchodilatory effect of deep inspiration on the dynamics of bronchoconstriction in mice.” J.H.T.

Bates, A. Cojocaru, and L.K.A. Lundblad. Journal of Applied Physiology. 103: 1696-1705, 2007.

A-183) “Lung impedance measurements are more useful than simpler measurements of lung function in

animal models of pulmonary disease.” (and rebuttal) J.H.T. Bates. (Point-Counterpoint with Wayne

Mitzner) Journal of Applied Physiology. 103: 1900-1904, 2007. “Last Word” pp. 1909.

16

A-184) “Transforming growth factor-1 suppresses airway hyperresponsiveness in allergic airway disease.”

J.F.Alcorn, L.M. Rinaldi, E.F. Jaffe, M. van Loon, J.H.T. Bates, Y.M.W. Janssen-Heininger, and C.G.

Irvin. American Journal of Respiratory and Critical Care Medicine. 176: 974-982, 2007.

A-185) “Heterogeneity of bronchoconstriction does not distinguish mild asthmatic subjects from healthy

controls when supine.” D.A. Kaminsky, C.G. Irvin, L.K.A. Lundblad, J. Thompson-Figueroa, J.

Klein, M.J. Sullivan, F. Flynn, S. Lang, L. Bourassa, S. Burns, and J.H.T. Bates. Journal of Applied

Physiology. 104: 10-19, 2008.

A-186) “Unrestrained video-assistant plethysmography: a noninvasive method for assessment of lung

mechanical function in small animals.” J.H.T. Bates, J. Thompson-Figueroa, L.K.A. Lundblad,

and C.G. Irvin. Journal of Applied Physiology. 104: 253-261, 2008.

A-187) “The synergistic interactions of allergic lung inflammation and intra-tracheal cationic protein.” J.H.T.

Bates, A. Cojocaru, H.C. Haverkamp, L.M. Rinaldi, and C.G. Irvin. American Journal of Respiratory

and Critical Care Medicine. 177: 261-268, 2008.

A-188) “In silico modeling of interstitial lung mechanics: implications for disease development and repair.” B.

Suki, A. Majumdar, M.A. Nuggent, and J.H.T. Bates. Drug Discovery Today: Disease Models. 4:139-

145, 2008.

A-189) “Computational assessment of airway wall stiffness in vivo in allergically inflamed mouse models of

asthma.” A. Cojocaru, C.G. Irvin, H.C. Haverkamp, and J.H.T. Bates. Journal of Applied Physiology.

104: 1601-1610, 2008.

A-190) “Extracellular matrix mechanics in lung parenchymal diseases.” B. Suki and J.H.T. Bates. Respiratory

Physiology & Neurobiology. 163: 33-43, 2008.

A-191) “Assessment of peripheral lung mechanics.” J.H.T. Bates and B. Suki. Respiratory Physiology &

Neurobiology. 163: 54-63, 2008.

A-192) “Modeling the dynamics of recruitment and derecruitment in mice with acute lung injury.” C.B.

Massa, G.B. Allen, and J.H.T. Bates. Journal of Applied Physiology. 105:1813-1821, 2008.

A-193) “A further theoretical analysis of why venous pressure rises after the onset of LV dysfunction.” S.

Magder, S. Veerassamy, J.H.T. Bates. Journal of Applied Physiology. 106: 81-90, 2009.

A-194) “Neither Fibrin nor PAI-1 Deficiency Protects Lung Function in a Mouse Model of Acute Lung

Injury.” G.B. Allen, M.E. Cloutier, Y.C. Larrabee, K. Tetenev, S.T. Smiley, and J.HT. Bates.

American Journal of Physiology – Lung, Cell and Molecular Physiology. 296: L277-L285, 2009.

A-195) “The Role of Time and Pressure on Individual Alveolar Recruitment.” S.P. Albert, J. DiRocco, G.B.

Allen, J.H.T. Bates, R. Lafollette, B. Kubiak, J. Fischer, S. Maroney, and G.F. Nieman. Journal of


A-196) “Physiologic dysfunction of the asthmatic lung. What’s going on down there anyway?” C.G. Irvin, and

J.H.T. Bates. Proceedings of the American Thoracic Society. 6: 306-311, 2009.

A-197) “Transient oscillatory force-length behavior of activated airway smooth muscle .” J.H.T. Bates, S.R.

Bullimore, A.Z. Politi, J. Sneyd, R.C. Anafi and A-M. Lauzon. American Journal of Physiology –

Lung, Cell and Molecular Physiology. 297: L362-L372, 2009.

A-198) “Animal models of asthma.” J.H.T. Bates, M. Rincon and C.G. Irvin. American Journal of Physiology

– Lung, Cell and Molecular Physiology. 297: L401-L410, 2009.

A-199) “Variation in the rapid shallow breathing index associated with common measurement techniques and

conditions.”. K.N. Patel, K. Ganatra, J.H.T. Bates, and M.P. Young. Respiratory Care. 54: 1462-1466,

2009.

17

A-200) ”Acid aspiration-induced airways hyperresponsiveness in mice.” T. Leclair, J. von Reyn , Y. Larrabee,

M. Cloutier, C.G. Irvin , J.H.T. Bates, and G.B. Allen. Journal of Applied Physiology. 107: 1763-

1770, 2009.

A-201) “Inhaled Salmeterol and/or Fluticasone Alters Structure/Function in a Murine Model of Allergic

Airways Disease.” E.P. Riesenfeld, M.J. Sullivan, J.A. Thompson-Figueroa, H.C. Haverkamp, L.K.A.

Lundblad, J.H.T. Bates, and C.G. Irvin. Respiratory Research. 11: 22, 2010.

A-202) “A breath biofeedback computer game for children with cystic fibrosis.” P.M. Bingham, J.H.T. Bates,

J. Thompson-Figueroa, and T.L. Lahiri. Clinical Pediatrics. 49: 337-342, 2010.

A-203) “The temporal variability of dominant frequency and complex fractionated atrial electrograms

constrains the validity of sequential mapping in human atrial fibrillation.” N. Habel, P. Znojkiewicz,

N. Thompson, J.G. Müller, B. Mason, J. Calame, S. Calame, S. Sharma, G. Mirchandani, D. Janks,

J.H.T. Bates, A. Noori, A. Karnbach, D.L. Lustgarten, B.E. Sobel, and P. Spector. Heart Rhythm. 7:

586-593, 2010.

A-204) “The influence of airway wall stiffness and parenchymal tethering on the dynamics of

bronchoconstriction.” M.A. Khan, R. Ellis, M.D. Inman, J. H.T. Bates, M.J. Sanderson, and L.J.

Janssen. American Journal of Physiology - Lung Cellular and Molecular Physiology. 299: L98-L108,

2010.

A-205) “A multiscale, spatially-distributed model of asthmatic airway hyper-responsiveness.” A. Z. Politi,

G.M. Donovan, M.H. Tawhai, M.J. Sanderson, A.-M. Lauzon, J.H. T. Bates, and J. Sneyd. Journal of

Theoretical Biology. 266: 614-624, 2010.

A-206) “Modeling the complex dynamics of derecruitment in the lung.” B. Ma, and J.H.T. Bates. Annals of


A-207) “A continuous-binding cross-linker model for passive airway smooth muscle.” G.M. Donovan, S.R.

Bullimore, A.J. Elvin, M.H. Tawhai, J.H.T. Bates, A.-M.Lauzon, and J. Sneyd. Biophysical Journal.

99: 3164-3171, 2010.

A-208) “Balancing robustness against the dangers of multiple attractors in a Hopfield-type model of biological

networks.” RC. Anafi, and J.H.T. Bates. PLoS ONE 5(12): e14413.

doi:10.1371/journal.pone.0014413, 2010.

A-209) “Effects of central airway shunting on the mechanical impedance of the mouse lung.” B.L. Schwartz,

R.C. Anafi, M. Aliyeva, J.A. Thompson-Figueroa, G.B. Allen, L.K.A. Lundblad, and J.H.T. Bates.


A-210) “Could an Increase in Airway Smooth Muscle Shortening Velocity Cause Airway

Hyperresponsiveness?.” S.R. Bullimore, S. Siddiqui, G.M. Donovan, J.G. Martin, J. Sneyd, J. H.T.

Bates and A.-M. Lauzon. American Journal of Physiology - Lung Cellular and Molecular Physiology.

300: L121-L131, 2011.

A-211) “Analysis of regional mechanics in canine lung injury using forced oscillations and 3-D image

registration. D.W. Kaczka, K. Cao, G.E. Christensen, J.H.T. Bates, and B.A. Simon. Annals of


A-212) “Detrimental effects of albuterol on airway responsiveness requires airway inflammation and is

independent of beta-receptor affinity in murine models of asthma.” L.K.A. Lundblad, L.M. Rinaldi,

M.E. Poynter, E.P. Riesenfeld, M. Wu, S. Aimi, L.M. Barone, J.H.T. Bates, and C.G. Irvin.

Respiratory Research. 12: 27, 2011.

A-212) “Quantifying the roles of tidal volume and PEEP in the pathogenesis of ventilator-induced lung

injury.” A.S. Seah, K.A. Grant, M. Aliyeva, G.B. Allen, and J.H.T. Bates. Annals of Biomedical

18

Engineering. 39: 1505-1516, 2011.

A-214) “Lung tissue mechanics as an emergent phenomenon.” B. Suki and J.H.T. Bates. Journal of Applied

Physiology. 110: 1111-1118, 2011.

A-215) “Effects of recruitment/derecruitment dynamics on the efficacy of variable ventilation.” B. Ma, B.

Suki, and J.H.T. Bates. Journal of Applied Physiology. 110: 1319-1326, 2011.

A-216) “Multi-scale lung modeling.” M. Tawhai and J.H.T. Bates. Journal of Applied Physiology. 110: 1466-

1472, 2011.

A-217) “Emergence of complex behavior: an interactive model of cardiac excitation provides a powerful tool

or understanding electrical propagation.” P.S. Spector, N. Habel, B.E. Sobel, and J.H.T. Bates.

Circulation: Arrhythmia & Electrophysiology. 4: 586-591, 2011.

A-218) “The mechanical determinants of airways hyperresponsiveness.” J.H.T. Bates, and G.N. Maksym.

CRC Critical Reviews in Biomedical Engineering. 39: 281-296, 2011.

A-219) “Electrogram fractionation: the relationship between spatio-temporal variation of tissue excitation and

electrode spatial resolution.” D.D. Correa de Sa, N. Thompson, J. Stinnett-Donnelly, P. Znojkiewicz,

N. Habel, J.G. Mueller, J.H.T. Bates, and P.S. Spector. Circulation: Arrhythmia & Electrophysiology.

4: 909-916, 2011.

A-220) “Effects of electrode size and configuration on the spatial resolution of intracardiac electrograms.” J.

Stinnett-Donnelly, N. Thompson, N. Habel, V. Petrov-Kondratov, J.H.T. Bates, and P. Spector.

Coronary Artery Disease. 23: 126-132, 2012.

A-221) “The Temporal Evolution of Airways Hyperresponsiveness and Inflammation.” E. Riesenfeld, G.B.

Allen, J.H.T. Bates, M.E. Poynter, M. Wu, S. Aimi, and L.K.A. Lundblad. Journal of Allergy and

Therapy. S1:005. doi:10.4172/2155-6121.S1-005, 2012.

A-222) “Airway responsiveness depends on the diffusion rate of methacholine across the airway wall.” J.H.T.

Bates, C.A. Stevenson, M. Aliyeva, and L.K.A. Lundblad. Journal of Applied Physiology. 112:1670-

1677, 2012.

A-223) “A multi-scale approach to airway hyperresponsiveness: from molecule to organ.” A.-M. Lauzon,

J.H.T. Bates, G. Donovan, M. Tawhai, J. Sneyd, and M.J. Sanderson. Frontiers in Computational

Physiology and Medicine. 3: article 191, 2012.

A-224) “Continuum vs. spring network models of airway-parenchymal interdependence.” B. Ma, and J.H.T.


A-225) “Ablation of multi-wavelet reentry: general principles and in silico analyses.” P.S. Spector, D.D.

Correa de Sa, E..Tischler, N. Thompson, N. Habel, J. Stinnett-Donnelly, B.E. Benson, P. Bielau, and

J.H.T. Bates. Europace. 14: v106-v111, 2012.

A-226) “Airway-parenchymal interdependence in the lung slice.” B. Ma, M.J. Sanderson, and J.H.T. Bates.

Respiratory Physiology & Neurobiology. 185: 211–216, 2013.

A-227) “Modeling and managing airway closure: implications for acute lung injury and asthma.” J.H.T. Bates.

Kokyu (Respiration Research – in Japanese). 32: 82-93, 2013.

A-228) “Linking the development of ventilator-induced injury to mechanical function in the lung.” B.J. Smith,

K.A. Grant, and J.H.T. Bates. Annals of Biomedical Engineering. 41: 527-536, 2013.

A-229) “The inflammatory twitch as a general strategy for controlling the host response.” J.J. Pothen, M.E.

Poynter, and J.H.T. Bates. Journal of Immunology. 190: 3510-3516, 2013.

A-230) “A progressive rupture model of soft tissue stress relaxation.” J.H.T. Bates, and Baoshun Ma. Annals

19

of Biomedical Engineering. 41: 1129-1138, 2013.

A-231) “Elucidating the fuzziness in physician decision making in ARDS.” D.B. Bernstein, B. Nguyen, G.B.

Allen, and J.H.T. Bates. Journal of Clinical Monitoring and Computing. 27:357–363, 2013.

A-232) “Influence of parenchymal heterogeneity on airway-parenchymal interdependence.” B. Ma, B. Breen,

and J.H.T. Bates. Respiratory Physiology & Neurobiology. 188: 94-101, 2013

A-233) “Assessing the progression of ventilator-induced lung injury in mice from dynamic pressure-volume

measurements.” B.J. Smith and J.H.T Bates. IEEE Transactions on Biomedical Engineering. 60:

3449-3457, 2013.

A-234) “Conference Report: Stem Cells and Cell Therapies in Lung Biology and Diseases. University of

Vermont, July 2011.” D.J. Weiss, J.H.T. Bates, T. Gilbert, W.C. Liles, C. Lutzko, J. Rajagopal, D.

Prockop. Annals of the American Thoracic Society. 10: S25-S44, 2013.

A-235) “Ablation of Multi-Wavelet Reentry Guided by Circuit Density and Distribution: Maximizing the

Probability of Circuit Annihilation.” R. Carrick, B. Benson, N. Habel, O.R.J. Bates, J.H.T. Bates, and

P.S. Spector. Circulation: Arrhythmia & Electrophysiology. 6:1229-1235, 2013.

A-236) “Mechanical interactions between adjacent airways in the lung.” B. Ma, and J.H.T. Bates. Journal of


A-237) “Improved Spatial Resolution and Electrogram Wave Direction Independence with the Use of an

Orthogonal Electrode Configuration.” N.C. Thompson, J. Stinnett-Donnelly, N.Habel, B. Benson,

J.H.T. Bates, B.E. Sobel, and P.E. Spector. Journal of Clinical Monitoring and Computing. 28:157-

163, 2014.

A-238) “Computational Models of Ventilator Induced Lung Injury and Surfactant Dysfunction.” J.H.T. Bates,

B.J. Smith, and G. B. Allen. Drug Discovery Today- Disease Models. (in press)

A-239) “Controlling mechanical ventilation in ARDS with fuzzy logic.” D.G. Bernstein, B. Nguyen, and

J.H.T. Bates. Journal of Critical Care. (in press)

A-240) “Variable ventilation as a diagnostic tool for the injured lung.” B.J. Smith and J.H.T. Bates. IEEE

Transactions on Biomedical Engineering. (in press).

A-241) “The non-allergic asthma of obesity: a matter of distal lung compliance.” A. Al-Alwan , J.H.T. Bates,

D. Chapman, D.A. Kaminsky, M.J. DeSarno, C.G. Irvin, and A.E. Dixon. American Journal of

Respiratory and Critical Care Medicine. (in press)

A-242) “A network model of correlated growth of tissue stiffening in pulmonary fibrosis.” C.L.N. Oliveira,

J.H.T. Bates, and B. Suki. New Journal of Physics. (in press)

Papers submitted

A-243) “Digital resolution enhancement of intracardiac excitation maps during atrial fibrillation.” K.B.

Palmer, N.C. Thompson, P.S. Spector, J. Kalifa, and J.H.T. Bates. Journal of Clinical Monitoring and

Computing. (submitted)

A-244) “Modelling the full range of behaviour exhibited by airway smooth muscle under varied strain-rate

amplitudes and deep inspirations." K. Murphy, J. Sneyd, M. Tawhai, J.H.T. Bates, A.-M. Lauzon, and

G. Donovan. Biophysical Journal. (submitted)

20

A-245) “Mapping multi-wavelet reentry without isochrones: An electrogram-guided approach to define

substrate distribution. B.E. Benson, R. Carrick, N. Habel, O. Bates, J.H.T. Bates, P. Bielau, P.

Spector. Circulation: Arrhythmia & Electrophysiology. (submitted)

A-246) “The physiological consequences of distinct asthma phenotypes in the obese.” D. Chapman, C.G.

Irvin, J.H.T. Bates, and A.E. Dixon. Respirology. (submitted)

A-247) “Mechanical breath profile of APRV impacts alveolar recruitment and micro-strain in acute lung

injury.” M. Kollisch-Singule, B. Emr, B. Smith, S. Roy, S. Jain, J. Satalin, K. Snyder, P. Andrews, N.

Habashi, J. Bates, W. Marx, G. Nieman, and L. Gatto. (submitted)

A-248) “Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis.”

D.L., A. Gazdhar, E. Lopez-Rodriguez, P. Mahavadi, A. Günther, J.H.T. Bates, B. Smith, T. Geiser,

M. Ochs, and L. Knudsen. American Journal of Respiratory Cell and Molecular Biology. (submitted)

A-249) “Reentrant Cardiac Arrhythmia: A Case of Dynamic Entrapment.” O.R.J. Bates, J.H.T. Bates, B. Suki,

and P.S. Spector. Journal of Theoretical Biology. (submitted)

A-250) “Mechanical Ventilation of the Lung at Risk of Acute Lung Injury: Harmful or Therapeutic Tool?” G.

Nieman, L. Gatto, W. Marx, J.H.T. Bates, and N. Habashi. Critical Care (submitted).

21

B) Conference Papers

B-1) "Identifying a model of respiratory mechanics using the interrupter technique". J.H.T. Bates, K. Brown

and T. Kochi. IEEE Engineering in Medicine and Biology Annual Conference, November 14-16,

1987. Proceedings pp. 1802-1803.

B-2) "Pressurization artifacts in pneumotachograph measurements of gas flow". J.H.T. Bates. Presented at

the Canadian Medical and Biological Engineering Society Meeting, June 28-30, Montreal, 1988.

Proceedings pp. 25-26.

B-3) "Separating tissue and gas flow effects in respiratory mechanics using gases of different physical

properties." J.H.T. Bates, J. Sato and B.L.K. Davey. Presented at the 6th IMEKO Conference on

Measurement in Clinical Medicine and the 8th Hungarian Conference on Biomedical Engineering,

Sopron, Hungary, August 29-31, 1990. Conference proceedings pg. 147-150.

B-4) "A model of airway-parenchymal interaction in the lung using simulated annealing". J.H.T. Bates, and

D.H. Eidelman. Presented at the Canadian Medical and Biological Engineering Society Meeting,

Toronto, June, 1992. Proceedings pp. 130-131.

B-5) "Monitoring respiratory mechanics in ventilated patients". J.H.T. Bates. In: Recent Advances in

Anesthesia, Pain, Intensive Care and Emergency. A. Gullo (Ed.) A.P.I.C.E., Trieste, 1992, pp. 325-

332.

B-6) "A mobile patient monitoring system for respiratory mechanics." J.H.T. Bates and T.F. Schuessler.

Presented at the 19th Annual Meeting of the Canadian Biomedical Engineering Society, May 12-15,

1993, Carleton University, Ottawa, Canada. Proceedings pp. 66-67.

B-7) "A computer controlled small animal ventilator." T.F. Schuessler and J.H.T. Bates. Presented at the

19th Annual Meeting of the Canadian Biomedical Engineering Society, May 12-15, 1993, Carleton

University, Ottawa, Canada. Proceedings pp. 68-69.

B-8) "A tissue strip oscillator and preconditioning protocol." G.N. Maksym, D. Navajas and J.H.T. Bates.

Presented at the 19th Annual Meeting of the Canadian Biomedical Engineering Society, May 12-15,

1993, Carleton University, Ottawa, Canada. Proceedings pp. 100-101.

B-9) "Estimating tracheal flow in small animals." T. F. Schuessler, J.H.T. Bates and G.N. Maksym.

Presented at the 15th Annual International Meeting of the I.E.E.E. Engineering in Medicine and

Biology Society, San Diego, October 28-31, 1993. Proceedings pp. 560-561.

B-10) "Monitoring respiratory mechanics during anesthesia." J.H.T. Bates, T.F. Schuessler, G. Dechman, P.

Ruiz-Neto and D. Chartrand. Presented at the 15th Annual International Meeting of the I.E.E.E.

Engineering in Medicine and Biology Society, San Diego, October 28-31, 1993. Proceedings pp. 653-

654.

B-11) "Lung parenchyma stress response to step strains." G.N. Maksym, J.H.T. Bates and D. Navajas.

Presented at the 15th Annual International Meeting of the I.E.E.E. Engineering in Medicine and

Biology Society, San Diego, October 28-31, 1993. Proceedings pp. 1116-1117.

B-12) "A non-blurring regularization scheme for electrical impedance tomography." T.F. Schuessler and

J.H.T. Bates. Presented at the 20th Annual Meeting of the Canadian Medical and Biological

Engineering Society, Vancouver, May, 1994. Proceedings pp. 10-11.

B-13) "Distributed modeling of nonlinear tissue elasticity." G.N. Maksym and J.H.T. Bates. Presented at the

20th Annual Meeting of the Canadian Medical and Biological Engineering Society, Vancouver, May,

1994. Proceedings pp. 138-139.

22

B-14) "An adaptive filter for the reduction of cardiogenic oscillations on esophageal pressure signals. T.F.

Schuessler, C.A. Volta, P. Goldberg, S.B. Gottfried, R.E. Kearney, and J.H.T. Bates. Presented at the

17th Annual International Meeting of the I.E.E.E. Engineering in Medicine and Biology, Montreal,

Quebec, Canada, September 1995. Paper no. 4.2.4.1.

B-15) "Utility of an esophageal reference electrode for thoracic electrical impedance tomography." T.F.

Schuessler and J.H.T. Bates. Presented at the 17th Annual International Meeting of the I.E.E.E.

Engineering in Medicine and Biology, Montreal, Quebec, Canada, September 1995. Paper no.

2.5.1.2.

B-16) "A theory for the basis of lung tissue elasticity." G.N. Maksym and J.H.T. Bates. Presented at the

17th Annual International Meeting of the I.E.E.E. Engineering in Medicine and Biology, Montreal,


B-17) "A branching lung model with distributed parameters." C. W. Thorpe and J.H.T. Bates. Presented at

the 17th Annual International Meeting of the I.E.E.E. Engineering in Medicine and Biology, Montreal,


B-18) "Time/frequency analysis of respiratory mechanics via amplitude modulation of multiple carriers."

J.H.T. Bates. Presented at the 17th Annual International Meeting of the I.E.E.E. Engineering in

Medicine and Biology, Montreal, Quebec, Canada, September 1995. Paper no. 4.5.3.20.

B-19) "A convergence estimator for the iterative reconstruction of electrical impedance tomography images."

T.F. Schuessler and J.H.T. Bates. Presented at the Annual Meeting of the I.E.E.E. Biomedical

Engineering Society, Amsterdam, 1996. Paper no. 38.

B-20) "Monitoring of lung volume in dogs with electrical impedance tomography." A. Adler, N. Shinozuka,

R. Guardo, Y. Berthiaume, and J.H.T. Bates. Presented at the Annual Meeting of the I.E.E.E.

Biomedical Engineering Society, Amsterdam, 1996. Paper no. 383.

B-21) “Fitting nonlinear time-domain models of respiratory mechanics to pressure-flow data from an

intubated patient.” J.H.T. Bates and P. Goldberg. Presented at the Joint Meeting of the BMES and

EMBS, Atlanta, October 13-16, 1999.

B-22) “A computer-controlled mechanical ventilator based on a rotating vane.” M. Ahmadi and J.H.T. Bates.

Presented at the Joint Meeting of the BMES and EMBS, Atlanta, October 13-16, 1999.

B-23) “Toward a nonlinear network theory of complex diseases.” J.H.T. Bates. Presented at the International

Conference on Complex Systems, Boston, June 25-30, 2006. Published in online proceedings at

http://necsi.org/events/iccs6/viewpaper.php?id=166

B-24) “Assessment of lung mechanics in mouse models of airways hyperresponsiveness.” J.H.T. Bates.

Presented at the World Congress on Biomechanics, Munich, July 29 - Aug 4, 2006. Medimond

International Proceedings pp. 325-329.

B-25) “Pulmonary mechanics: a system identification perspective.” J.H.T. Bates. Presented at the 31st

Annual International Conference of the I.E.E.E. Engineering in Medicine and Biology Society,

Minneapolis, MN, Sept. 2-6, 2009. Proceedings pp. 170-172.

B-26) “On the ill-conditioned nature of the intracardiac inverse problem.” J.H.T. Bates and Peter S. Spector.

Presented at the 31st Annual International Conference of the I.E.E.E. Engineering in Medicine and

Biology Society, Minneapolis, MN, Sept. 2-6, 2009. Proceedings pp. 3929-3931.

23

C) Books

C-1 “Lung Mechanics. An Inverse Modeling Approach.” J.H.T. Bates. Cambridge University Press,

Cambridge, UK. 2009.

24

D) Book Chapters

D-1) "A lumped-parameter nonlinear model of relaxed expiration of the respiratory system". J.H.T. Bates.

In: Advances in Bioengineering (BED vol 2). S.A. Lantz and A.I. King, eds., ASME, New York, pp.

68-69, 1986.

D-2) "Breathing patterns and the concepts of minimum respiratory work and minimum effort". J.H.T. Bates

and J. Milic-Emili. In: Neurobiology of the Control of Breathing, Eds. C. von Euler and H.

Lagercrantz, Raven Press, New York, 1987. pp. 243-249.

D-3) "The Respiratory System". J.H.T. Bates. In: Concise Encyclopaedia on Biological and Biomedical

Measurement Systems. (P.A. Payne, ed.), Pergamon Press, Oxford, 1991, pp. 325-330.

D-4) "Measuring Pulmonary Compliance". J.H.T. Bates. Cardiopulmonary Review. SensorMedics

Continuing Medical Education Group, Yorba Linda, CA, 1994.

D-5) "Measurement of flow and volume." J.H.T. Bates, M.J. Turner, C.J. Lanteri, B. Jonson and P.D. SLy.

In: Infant Respiratory Function Testing: A Practical Guide. J. Stocks, P.D. Sly, R.S. Tepper and W.J.

Morgan, eds. Wiley, 1996, pp. 81-110.

D-6) "The temporal dynamics of acute induced bronchoconstriction." J.H.T. Bates. In: Bioengineering

Approaches to Pulmonary Physiology and Medicine. M.C.K. Khoo, ed. Plenum, 1996, pp. 213-226.

D-7) “Linear systems and the 1-D Fourier transform.” J.H.T. Bates. In: The Fourier Transform in

Biomedical Engineering, T.M. Peters and J.C. Williams, eds. Birkhauser, Boston, 1997, pp. 25-52.

D-8) “The discrete Fourier transform and the fast Fourier transform.” T.M. Peters and J.H.T. Bates. In: The

Fourier Transform in Biomedical Engineering, T.M. Peters and J.C. Williams, eds. Birkhauser,

Boston, 1997, pp. 175-194.

D-9) "Assessment of mechanics." J.H.T. Bates. In: The Physiological Basis of Ventilatory Support, J.J.

Marini and A.S. Slutsky, eds., .Marcel Dekker, New York, 1998, pp. 231-259.

D-10) “Assessment of lung function in mechanically ventilated patients.” J.H.T. Bates. In: Yearbook of

Intensive Care and Emergency Medicine, J.-L. Vincent, Ed., Springer-Verlag, Berlin, 2002, pp. 579-

586.

D-11) “Optimal delivery of recruitment maneuvers in the injured lung.” J.H.T. Bates and G.B. Allen.

Yearbook of Intensive Care and Emergency Medicine, J.-L. Vincent, Ed., Springer-Verlag, Berlin,

2004, pp 429-435.

D-12) “The physics of expiratory flow limitation.” J.H.T. Bates. Physiologic Basis of Respiratory Disease. Q.

Hamid, J. Shannon, and J. Martin, Eds. BC Dekker, Hamilton, Ontario, 2005, pp. 55-60.

D-13) “Measurement technique in respiratory mechanics.” J.H.T. Bates. Physiologic Basis of Respiratory

Disease. Q. Hamid, J. Shannon, and J. Martin, Eds. BC Dekker, Hamilton, Ontario, 2005, pp. 623-

637.

D-14) “Pulmonary mechanics.” J.H.T. Bates. Wiley Encyclopedia of Biomedical Engineering. M. Akay, Ed.,

Wiley, New York, 2006. DOI: 10.1002/9780471740360.ebs0982. Article Online Posting Date: April

14, 2006

D-15) “Closed-loop ventilation.” J.H.T. Bates. Principles and Practice of Mechanical Ventilation, 2nd

Edition. M. Tobin, Ed., McGraw-Hill, New York, 2006, pp. 365-371.

D-16) “The Netter Collection of Medical Illustrations: Respiratory System.” Second edition (Ed. D.K.

Kaminsky). J.H.T. Bates contributed to Section 2: “Physiology, Pulmonary Mechanics and Gas

Exchange.” Elsevier Saunders, Philadelphia, 2011.

http://www3.interscience.wiley.com/doiinfo.html

25

D-17) “Complexity and emergent phenomena.” B. Suki, J.H.T. Bates, and U. Frey. Handbook of Physiology.

J.J. Fredberg, Ed. American Physiological Society, 2011, Vol. 1, pp. 995 - 1029.

D-18) “Oscillation mechanics of the respiratory system.” J.H.T. Bates, C.G. Irvin, R. Farre and Z. Hantos.

Handbook of Physiology. J.J. Fredberg, Ed. American Physiological Society. Vol 1, pp. 1233-1272,

2011.

D-19) “Animal models of asthma.” J.H.T. Bates, M. Rincon, and C.G. Irvin. Animal Models of Disease:

Translational Medicine Perspective for Drug Discovery and Development. X. Wang, Ed. Bentham

eBooks, pp. 167-195, 2012.

D-20) “Mechanical properties of the lung.” J.H.T. Bates. Comparative Biology of the Lung. J. Tepper, Ed.,

CRC Press. (in press)

D-21) “Measurements in Pulmonology.” J.H.T. Bates, D.W. Kaczka, and G.K. Prisk. The CRC

Physiological Measurement Handbook. John G. Webster, Ed. Taylor and Francis (in press).

26

E) Editorials and Letters

E-1 Reply to Letter-to-the-Editor concerning the paper "Quasi-static pressure-volume hysteresis in the

canine respiratory system in vivo." F. Shardonofsky, J. Sato and J.H.T. Bates. Journal of Applied

Physiology. 69: pp. 2317-2318, 1990.

E-2) “Detecting airways obstruction from the tidal flow profile.” J.H.T. Bates. European Respiratory

Journal (Editorial). 12: 1008-1009, 1998.

E-3) Reply to Letter-to-the-Editor concerning the paper “A reevaluation of the validity of unrestrained

plethysmography in mice.” L.K.A. Lundblad, C.G. Irvin and J.H.T. Bates. Journal of Applied

Physiology. 94: 828-832, 2003

E-4) “The use and misuse of Penh in animal models of lung disease.” J.H.T. Bates, C. G. Irvin, V.

Brusasco, J. Drazen, J. Fredberg, S. Loring, D. Eidelman, M. Ludwig, P. Macklem, J. Martin, J. Milic-

Emili, Z. Hantos, R. Hyatt, S. Lai-Fook, A. Leff, J. Solway, K. Lutchen, B. Suki, W. Mitzner, P. Pare,

N. Pride, and P. Sly. American Journal of Respiratory Cell and Molecular Biology. 31: 373-374, 2004.

F-5) “Penh is not a measure of airway resistance!”. L.K.A. Lundblad, C.G. Irvin, Z. Hantos, P. Sly, W.

Mitzner and J.H.T. Bates. European Respiratory Journal (Letter). 30: 805, 2007.

F-6) “How should airway smooth muscle be punished for causing asthma?” J.H.T. Bates. Journal of

Applied Physiology (Editorial). 104: 575-576, 2008.

F-7) “Mucous obstruction and airway hyperresponsiveness in mice.” L.K.A. Lundblad, J. Thompson-

Figueroa, G.B. Allen, L. Rinaldi, R.J. Norton, C.G. Irvin and J.H.T. Bates. American Journal of

Respiratory and Critical Care Medicine (Reply to letter). 177:1171-1172, 2008.

F-8) “Emergency medicine.” J.H.T. Bates. Journal of Applied Physiology (Commentary). 104: 1849, 2008.

F-9) “Lung tissue mechanics and the occult”. J.H.T. Bates. Biomedical Engineering Society Bulletin

(Viewpoint). 32: 13-14, 2008.

F-10) “Purists versus pragmatists.” JHT Bates. Journal of Applied Physiology (Commentary). 105: 1983.

E-11) “The Multi-Scale Manifestations of Airway Smooth Muscle Contraction in the Lung.” J.H.T. Bates.

Journal of Applied Physiology (Editorial). 109: 269-270, 2010.

E-12) “Airway resistance: synonyms, surrogates, and precision.” Z. Hantos, J.H.T. Bates, C.G. Irvin, L.K.A.

Lundblad, and P.D. Sly,. American Journal of Physiology – Lung, Cellular and Molecular Physiology

(Letter). 300: L506, 2011.

E-13) “Emergent behavior in lung structure and function." B.Suki, and J.H.T. Bates. Journal of Applied

Physiology (Editorial). 110: 1109-1110, 2011.

E-14) “Proceedings from the Montebello round table discussion. Second annual conference on complexity

and variability discusses research that brings innovation to the bedside.” A.J.E. Seely, S.A. Kauffman,

J.H.T. Bates, P.T. Macklem, B. Suki, J.C. Marshall, A.I. Batchinsky, J.L. Perez-Velazquez, A. Seiver,

C. McGregor, G.N. Maksym, M.V. Kamath, T. Similowski, T.G. Buchman, C. Letellier, M. Filoche,

M.G. Frasch, C. Straus, L. Glass, P.J. Godin, J.A. Morris, D. Sow, V. Nenadovic, R.C. Arnold, P.

Norris, and J.R. Moorman. Journal of Critical Care (Editorial). 26: 325-327, 2011.

E-15) “Useful models of asthma need to properly phenotype airway narrowing.” Z. Hantos, L. Lundblad,

J.H.T. Bates, C.G. Irvin, P.D. Sly, and W. Mitzner. American Journal of Respiratory Cell and

Molecular Biology (Letter). 45: 1272-1273, 2011.

E-16) “Preface”. D.W. Kaczka, and J.H.T. Bates. CRC Critical Reviews in Biomedical Engineering. 39:

261-262, 2011.

27

E-17) “Airway resistance: synonyms, surrogates, and precision.” Z. Hantos, J.H.T. Bates, C.G. Irvin, L.K.A..

Lundblad, and P.D. Sly. American Journal of Physiology – Lung Cell and Molecular Physiology

(Letter). 300: L506, 2011.

E-18) “Pleural effusion in ARDS – water, water, everywhere, nor any drop to drain.” M.F. Vidal Melo, and

J.H.T. Bates. Critical Care Medicine (Editorial). 41: 1133-1134, 2013.

E-19) “Understanding alveolar mechanics – it is just a matter of time (Editorial)?” J.H.T. Bates. Critical Care

Medicine. Critical Care Medicine (Editorial). 41: 1374-1375, 2013.

E-20) “Of Course Respiratory Mechanics Are Related To Airway Inflammation in Asthma! The More

Difficult Question Is ‘Why?’” J.H.T. Bates. Clinical & Experimental Allergy (Editorial). 43: 488–490,

2013.

E-21) “Can’t decide whether to chase your favorite horse? Groom it first with Occam’s razor.” J.H.T. Bates.

Journal of Applied Physiology (Commentary). 116: 116, 2014.

28

F) Abstracts and Conference Presentations

F-1) "The estimation of cardiac output from respiratory gases by a computer modelling technique". J.H.T.

Bates and A.E. McKinnon. Presented at The Meeting of the Australasian College of Physical

Scientists and Engineers in Medicine and Biology, Christchurch, New Zealand, August 1980,

Proceedings pp. 27.

F-2) "The determination of a model for plasma clearance of nconjugated (14)D-cholic acid in humans".

J.H.T. Bates, D.M. Collins, A.H. Maslowski, A.E. McKinnon and C.B. Campbell. New Zealand

Medical Journal, vol 91: pp. 405, 1980.

F-3) "Computer processing of autoanalyser data". J.H.T. Bates, T.A. Walmsley and A.E. McKinnon.

Presented at The Conference of The New Zealand Association of Clinical Biochemists, Wellington,

New Zealand, August 1980, Proceedings pp. 19.

F-4) "A multiple-breath method for determining pulmonary capillary blood flow by computer model

fitting". J.H.T. Bates and A.E. McKinnon. New Zealand Medical Journal, vol 94: pp. 353, 1981.

F-5) "Correcting for apparatus errors in mass spectrometer measurements of gas concentration". J.H.T.

Bates, G.K. Prisk and T.E. Tanner. New Zealand Medical Journal, vol 95: pp. 783, 1982.

F-6) "Computational aspects of physiological system modelling". R.H.T. Bates, J.H.T. Bates, P.J. Bones,

R.P. Millane and A.D. Seagar. Presented at BECON'82, the Australian National Bio-Medical

Engineering Conference, Clunies Ross House, Melbourne, Australia, 29 November - 1 December,

1982, Proceedings pp. 4.

F-7) "Lipoprotein metabolism in type III hyperlipoproteinaemia". D.E. Janus, S. Grant, J. Bates and R.

Wootton. Presented to The Christchurch Medical Research Society, (13/4/83), The Australian

Athersclerosis Group (5/5/83)and The Americal Heart Association Meeting(16/11/83).

F-8) "A modeling study of the consequences of constant flow during inspiration". J.H.T. Bates, Andrea

Rossi and Joseph Milic-Emili. Presented at The Fall meeting of the American Physiological Society,

August 26-31, Lexington, Kentucky. Abstract in The Physiologist, vol 27: pp. 213, 1984.

F-9) "Relaxed expirations and viscoelasticity in the normal dog". J.H.T. Bates, D. Chartrand, M. Decramer

and J. Milic-Emili. Presented at The FASEB Meeting, 21-26 April 1985, Anaheim, CA. Abstract in

Federation Proceedings, vol 44: pp. 440, 1985.

F-10) "Upper airway responses to inhaled methacholine in spontaneously breathing anesthetized rats". G.U.

DiMaria, C.G. Wang, J.H.T. Bates and J.G. Martin. Presented at The American Thoracic Society

Meeting, 12-15 May 1985, Anaheim, CA. Abstract in American Review of Respiratory Diseases, vol

131: part 2, pp. A282, 1985.

F-11) "Methacholine induced airway responses in anesthetized inbred rats". C.G. Wang, G.U. DiMaria,

J.H.T. Bates, R. Guttmann and J.G. Martin. Presented at The American Thoracic Society Meeting,

12-15 May 1985, Anaheim, CA. Abstract in American Review of Respiratory Diseases, vol 131: part

2, pp. A282, 1985.

F-12) "Respiratory mechanics during constant flow inflation in mechanically ventilated patients with acute

respiratory failure". A. Rossi, S.B. Gottfried, J.H.T. Bates, L. Zocchi, A. Grassino and J. Milic-Emili.

Presented at The Annual Meeting of the Lung Mechanics Group, Societas Europaea Physiologiae

Clinicae Respiratoriae. The Hague, 26 June, 1985. Abstract in Bulletin Europeen de Physiopathologie

Respiratoire, vol 21: suppl, pp. 56M, 1985.

F-13) "Noninvasive determination of frequency-dependence of respiratory resistance in mechanically

ventilated patients". A. Rossi, J.H.T. Bates, S.B. Gottfried, B.D. Higgs, L. Zocchi, A. Grassino and J.

29

Milic-Emili. Presented at The American Thoracic Society Meeting, Anaheim, CA, 12-15 May 1985.

Abstract in American Review of Respiratory Diseases, vol 131: part 2, pp. A133, 1985.

F-14) "A comparison of upper and lower airway responses to inhaled methacholine". G.U. DiMaria, C.G.

Wang, J.H.T. Bates and J.G. Martin. Presented at the Meeting of The American College of Chest

Physicians, Sydney, Australia, August, 1985.

F-15) "A comparison of upper and lower airway responses to inhaled methacholine in the rat". G.U. Di

Maria, C.G. Wang, J.H.T. Bates and J.G. Martin. Presented at The American Thoracic Society

Meeting, Kansas City, 11-14 May 1986. Abstract in American Review of Respiratory Diseases. vol

133: pp. A15, 1986.

F-16) "The effect of changing arterial CO2 concentration on respiratory mechanics in the cat". P.D. Sly, T.

Kochi, S. Okubo, J.H.T. Bates and J. Milic-Emili. Presented at The American Thoracic Society

Meeting, Kansas City, 11-14 May 1986. Abstract in American Review of Respiratory Diseases. vol

133: pp. A386, 1986.

F-17) "The measurement of respiratory resistance by flow interruption is affected by non-instantaneous

occlusion of the airway opening". J.H.T. Bates, I.W. Hunter, P.D. Sly, S. Okubo, S. Filiatrault and J.

Milic-Emili. Presented at The Fall Meeting of The American Physiological Society, New Orleans,

October 5-9, 1986. Abstract in The Physiologist, vol 29: pp. 144, 1986.

F-18) "Hypercapnia has frequency dependent effects on resistance in the cat". P.D. Sly, J.H.T. Bates, T.

Kochi, S. Okubo and J. Milic-Emili. Presented at The Fall Meeting of The American Physiological

Society, New Orleans, October 5-9, 1986. Abstract in The Physiologist, vol 29: pp. 144, 1986.

F-19) "The physiological meaning of interrupter resistance elucidated by simultaneous measurements of

alveolar pressures". J.H.T. Bates, P.D. Sly, M. Ludwig, K. Brown, J. Martin and J.J. Fredberg.

Presented at The FASEB Meeting, Washington DC, 29 March - 2 April 1987. Abstract in Federation

Proceedings, vol 46: pp. 1107, 1987.

F-20) "Heterogeneity in alveolar pressures during relaxed expiration after induced bronchoconstriction in the

mongrel dog". M.S. Ludwig, P.D. Sly, K. Brown, J. Martin, J.J. Fredberg and J.H.T. Bates. Presented

at The Meeting of the American Thoracic Society, New Orleans, 10-13 May 1987. Abstract in

American Review of Respiratory Diseases, vol 135: pp. A197, 1987.

F-21) "Model simulations of flow-volume loops in ventilated infants". K.A. Brown, P.D. Sly, J.H.T. Bates

and J. Milic-Emili. Presented at The Meeting of the American Thoracic Society, New Orleans, 10-13

May 1987. Abstract in American Review of Respiratory Diseases, vol 135: pp. A68, 1987.

F-22) "Maximal methacholine-induced bronchoconstriction in the cat: effects of lung volume and vagal

section". P.D. Sly, K.A. Brown, J.H.T. Bates, J. Milic-Emili, P.T. Macklem and J.G. Martin.

Presented at The Meeting of the American Thoracic Society, New Orleans, 10-13 May 1987. Abstract

in American Review of Respiratory Diseases, vol 135: pp. A93, 1987.

F-23) "Can mouth pressure be used to measure alveolar pressure in infants?" P.D. Sly, K.A. Brown, M.

Ludwig, J.G. Martin, J.J. Fredberg and J.H.T. Bates. Presented at The Meeting of the American

Thoracic Society, New Orleans, 10-13 May 1987. Abstract in American Review of Respiratory

Diseases, vol 135: pp. A237, 1987.

F-24) "Physical limitations to the use of the interrupter technique in infants". P.D. Sly, J.H.T. Bates and J.

Milic-Emili. Presented at The Meeting of the American Thoracic Society, New Orleans, 10-14 May

1987. Abstract in American Review of Respiratory Diseases, vol 135: pp. A237, 1987.

F-25) "Deconvolving noisy signals with models of the noise". J.H.T. Bates. Presented at The 40th Annual

Conference on Engineering in Medicine and Biology, of the Alliance for Engineering in Medicine and

30

Biology, Niagra Falls, NY, 10-13 September 1987, Proceedings pp. 252.

F-26) "A mechanical model of the chest wall during expiration identified using flow interruption". J.H.T.

Bates, K. Brown, and T. Kochi. Presented at The Fall Meeting of the American Physiological Society,

San Diego, 11-15 October 1987. Abstract in The Physiologist, vol 30: pp. 171, 1987.

F-27) "A model-fitting approach to the estimation of respiratory mechanical parameters". J.H.T. Bates.

Presented at The American Thoracic Society Meeting, Las Vegas, 8-11 May 1988. Abstract in

American Review of Respiratory Diseases, vol 137: pp. 191, 1988.

F-28) "Dose response characteristics of lung parenchymal tissues and peripheral airways". M.S. Ludwig,

P.D. Sly, M. Bowman, G. Sturn, and J.H.T. Bates. Presented at The American Thoracic Society

Meeting, Las Vegas, 8-11 May 1988. Abstract in American Review of Respiratory Diseases, vol 137:

pp. 377, 1988.

F-29) "Stress adaptation and hysteresis during tidal ventilation in normal dogs revealed by flow

interruption". F. Shardonofsky, D.E. Stewart, J. Milic-Emili and J.H.T. Bates. Presented at The

FASEB meeting, Las Vegas, 1-5 May 1988. Abstract in The FASEB Journal, vol 2: pp. A1268, 1988.

F-30) "Low frequency dependence of respiratory resistance and elastance from multiple linear regression and

relaxed expirations". J.H.T. Bates, F. Shardonofsky, and D.E. Stewart. Presented at The FASEB

meeting, Las Vegas, 1-5 May 1988. Abstract in The FASEB Journal, vol 2: pp. A1269, 1988.

F-31) "Pressure generation by the respiratory muscles in anesthetized dogs is suppressed by airway

occlusion". D.E. Stewart, F. Shardonofsky, and J.H.T. Bates. Presented at The FASEB meeting, Las

Vegas, 1-5 May 1988. Abstract in The FASEB Journal, vol 2: pp. A1510, 1988.

F-32) "Effet de la temperature sur la cinetique de l'efflux du melphalan dans les cellules d'ovaire de hamster

chinois". D.A. Bates, S. Desaulniers, B. Courtemanche and J.H.T. Bates. Presented at The ACFAS

Conference, Monteal, May 1988.

F-33) "Modeling the low-frequency behaviour of the respiratory system". J.H.T. Bates. Presented at The

World Congress on Medical Physics and Biomedical Engineering, San Antonio, 6-12 August 1988.

Abstract in Physics in Medicine and Biology, vol 33: suppl 1, pp. 217, 1988.

F-34) "Breath-to-breath variability in different phases of the breathing cycle in anesthetized dogs at rest". W.

de Vries and J.H.T. Bates. Presented at The Fall Meeting of the American Physiological Society,

Montreal, 9-13 October 1988. Abstract in The Physiologist, vol 31: pp. A174, 1988.

F-35) "The resonant frequency of central airways gas investigated with gases of different densities". J. Sato,

T. Abe, P. Romero, and J.H.T. Bates. Presented at The Fall Meeting of the American Society,

Montreal, 9-13 October 1988. Abstract in The Physiologist, vol 31: pp. A221, 1988.

F-36) "Fitting of exponential pressure-volume curves: Sensitivity to noise and completeness of data". D.H.

Eidelman, H. Ghezzo, and J.H.T. Bates. Presented at The Fall Meeting of the American Physiological

Society, Montreal, 9-13 October 1988. Abstract in The Physiologist, vol 31: pp. A221, 1988.

F-37) "The effect of temperature on efflux kinetics of melphalan in CHO cells". D.A. Bates, S. Desaulniers,

L. Simoneau, B. Courtemanche and J.H.T. Bates. Presented at The North American Hyperthermia

Group 9th Annual Meeting, Seattle, 1989.

F-38) "The effects of numerical integration errors on least-squares estimates of respiratory resistance and

elastance". G.K. Prisk and J.H.T. Bates. Presented at The FASEB Meeting, New Orleans, 19-23 May

1989. Abstract in The FASEB Journal, vol 3: pp. A240, 1989.

F-39) "The effect of continuing gas exchange on very low frequency measurements of respiratory

mechanics". H.J.B. Guy, G.K. Prisk and J.H.T. Bates. Presentation at The FASEB Meeting, New

Orleans, 19-23 May 1989. Abstract in The FASEB Journal, vol 3: pp. A688, 1989.

31

F-40) "Quasi-static hysteresis in the respiratory system of the normal dog". F. Shardonofsky, J. Sato and

J.H.T. Bates. Presented at The American Thoracic Society Meeting, Cincinnati, 14-17 May 1989.

Abstract in American Review of Respiratory Diseases, vol 139: pp. A102, 1989.

F-41) "A comparison of the dose response behaviour of canine airways and parenchyma". M.S. Ludwig,

P.V. Romero and J.H.T. Bates. Presented at The American Thoracic Society Meeting, Cincinnati,

14-17 May 1989. Abstract in American Review of Respiratory Diseases, vol 139: pp. A133, 1989.

F-42) "Non-adiabatic gas compression in body plethysmographs". J. Sato, F. Shardonofsky and J.H.T. Bates.

Presented at The American Thoracic Society Meeting, Cincinnati, 14-17 May 1989. Abstract in

American Review of Respiratory Diseases, vol 139: pp. A291, 1989.

F-43) "Effect of the thermodynamics of an infant plethysmograph on the measurement of thoracic gas

volume". P.D. Sly, C. Lanteri and J.H.T. Bates. Presented at The American Thoracic Society Meeting,

Cincinnati, 14-17 May 1989. Abstract in American Review of Respiratory Diseases, vol 139: pp.

A382, 1989.

F-44) "A lumped-parameter model for the low-frequency behaviour of the canine respiratory system". J.H.T.

Bates, F. Shardonofsky and J. Sato. Presented at The 24th Annual Meeting of the SEPCR, Lausanne,

26-30 June 1989. Abstract in The European Respiratory Journal, vol 2: suppl 5, pp. 338s, 1989.

F-45) "Upper airway late responses of sensitized rats to antigen provocation". L. Xu, D.H. Eidelman, J.H.T.

Bates and J.G. Martin. Presented at The Fall Meeting of the American Physiological Society,

Rochester MN, 15-18 October 1989. Abstract in The Physiologist, vol 32: pp. 160, 1989.

F-46) "Recursive least-squares estimation of time-varying respiratory parameters". A.-M. Lauzon and J.H.T.

Bates. Presented at The Fall Meeting of the American Physiological Society, Rochester MN, 15-18

October 1989. Abstract in The Physiologist, vol 32: pp. 194, 1989.

F-47) "Respiratory mechanics determined by forced oscillations through an alveolar capsule". J.H.T. Bates

and S. Filiatrault. Presented at The Fall Meeting of the American Physiological Society, Rochester

MN, 15-18 October 1989. Abstract in The Physiologist, vol 32: pp. 194, 1989.

F-48) "Respiratory mechanics in the rat". D.H. Eidelman, P. Saldiva, M. Ludwig, J.H.T. Bates, J. Milic-

Emili and W. Zin. Presented at The Fall Meeting of the American Physiological Society, Rochester

MN, 15-18 October 1989. Abstract in The Physiologist, vol 32: pp. 194, 1989.

F-49) "The resistance of the respiratory system and the pulmonary airways between 0 and 5 Hz". J. Sato,

B.L.K. Davey, F. Shardonofsky and J.H.T. Bates. Presented at The FASEB Meeting, Washington DC,

April 1990. Abstract in The FASEB Journal, vol 4: pp. A292, 1990.

F-50) "Spectral analysis of the phrenic neurogram throughout inspiration in the dog". B.L.K. Davey, G.

Benchetrit, F.R. Shardonofsky and J.H.T. Bates. Presented at The FASEB Meeting, Washington DC,

April 1990. Abstract in The FASEB Journal, vol 4: pp. A1103, 1990.

F-51) "The effect of pulmonary fibrosis on the distribution of edema: computed tomography (CT) scanning

and morphology". R.P. Michel, M.P. Zwikler, J.H.T. Bates and T.M. Peters. Presented at The World

Conference on Lung Health, Boston, 2-24 May 1990. Abstract in American Review of Respiratory

Diseases, vol 141: pp. A298, 1990

F-52) "Effect of smooth muscle orientation on bronchoconstriction". J.H.T. Bates and J.G. Martin. Presented

at The World Conference on Lung Health, Boston, 20-24 May 1990. Abstract in American Review of

Respiratory Diseases, vol 141: pp. A362, 1990.

F-53) "Limitations of modelling in the interpretation of data in respiratory mechanics." J.H.T. Bates.

Presented at the Joint Meeting SEP-SEPCR, London September 9-14, 1990. (Invited speaker)

Abstract in The European Respiratory Journal, vol 3: suppl 10, pp. 64s, 1990.

32

F-54) "Partitioning of respiratory mechanics in mechanically ventilated COPD patients." G. Polese, A.

Rossi, G. Brandi, L. Appendini, R. Poggi, J.H.T. Bates and R. Brandolese. Presented at the Joint

Meeting SEP-SEPCR, London September 9-14, 1990. Abstract in The European Respiratory Journal,

vol 3: suppl 10, 101s, 1990.

F-55) "Maximal relaxation rate (MRR) of transdiaphragmatic pressure after exercise in healthy subjects." L.

Appendini, G. Vilianis, S. Cardellino, G. Rossi, J.H.T. Bates, L. Dal Vecchio, G. Brandi and A. Rossi.

Presented at the Joint Meeting SEP-SEPCR, London September 9-14, 1990. Abstract in The European

Respiratory Journals, vol 3: suppl 10, pp. 263s, 1990.

F-56) "A nonlinear viscoelastic model of lung tissue mechanics." B. Suki and J.H.T. Bates. Presented at the

Fall Meeting of The American Physiological Society, October 6-10, 1990, Orlando. Abstract in The

Physiologist, vol 33: pp. A-83, 1990.

F-57) "Airways mechanics during large amplitude low frequency oscillation." J. Sato, B.L.K. Davey and

J.H.T. Bates. Presented at the Fall Meeting of The American Physiological Society, October 6-10,

1990, Orlando. Abstract in The Physiologist, vol 33: pp. A-84, 1990.

F-58) "Effect of pleural effusion on respiratory system mechanics." G. Dechman, J. Sato and J.H.T. Bates.

Presented at the FASEB Meeting, Atlanta, 1991. Abstract in The FASEB Journal, vol 5: pp. A1136,

1991.

F-59) "A comparison of interrupter and forced oscillation measurements of respiratory system resistance in

dogs." J.H.T. Bates, B. Daroczy, and Z. Hantos. Presented at the FASEB Meeting, Atlanta, 1991.

Abstract in The FASEB Journal, vol 5: pp. A1136, 1991.

F-60) "The resistance of lung and lung tissue between 0 and 10 Hz in immature rabbits: response to

methacholine." R. Tepper, J. Sato, B. Suki, J.G. Martin, and J.H.T. Bates. Presented at the American

Thoracic Society Meeting, Anaheim, 1991. Abstract in American Review of Respiratory Disease, vol

143: pp. A415, 1991.

F-61) "Chest wall mechanics in mechanically ventilated patients." G. Polese, A. Rossi, G. Brandi, L.

Appendini, R. Poggi, J.H.T. Bates, and R. Brandolese. Presented at the American Thoracic Society

Meeting, Anaheim, 1991. Abstract in American Review of Respiratory Disease, vol 143: pp. A480,

1991.

F-62) "Measurement of regional lung impedance by forced oscillations through an alveolar capsule." J.H.T.

Bates and B.L.K. Davey. Presented at the World congress on Medical Physics and Biomedical

Engineering. Kyoto, Japan, July 7-12, 1991. Abstract in Medical & Biological Engineering &

Computing, vol 29: suppl, pp. 456, 1991.

F-63) "A non-statistical approach to estimating confidence intervals about the parameters of a model of

respiratory system mechanics." J.H.T. Bates and A.-M. Lauzon. Presented at the World congress on

Medical Physics and Biomedical Engineering. Kyoto, Japan, July 7-12, 1991. Abstract in Medical &

Biological Engineering & Computing, vol 29: suppl, pp. 496, 1991.

F-64) "Regularized iterative deblurring of a point spread invariant blur." J.H.T. Bates and B.L.K. Davey.

Presented at the special Richard H.T. Bates Memorial Session at the joint North American Radio

Science and U.R.S.I. Meeting, London, Ontario, July 24-28, 1991. Abstract: proceedings page 697.

F-65) "Airway pressure-flow relationships in the dog: derivation of a model and its implications for

measurement of tissue mechanics." J.H.T. Bates, B. Suki, J. Sato, and B.L.K. Davey. Presented at the

European Respiratory Society Meeting, Brussels, September 21-26, 1991. Abstract in The European

Respiratory Journal, 4: suppl 14, pp. 430s, 1991.

F-66) "Time-course of induced bronchoconstriction assessed by recursive least-squares." A.-M. Lauzon and

33

J.H.T. Bates. Presented at the European Respiratory Society Meeting, Brussels, September 21-26,

1991. Abstract in The European Respiratory Journal, 4: suppl 14, pp. 461s, 1991.

F-67) "Etudes sur la mecanique des systemes respiratoires." J.H.T. Bates. L'Union Medicale du Canada,

Sept/Oct, 1991.

F-68) "Dynamics of acute histamine-induced bronchoconstriction at fixed lung volume in the dog." J.H.T.

Bates and R. Peslin. Presented at the FASEB Meeting, Anaheim, CA, April 5-9, 1992. Abstract in

The FASEB Journal, 6: part 1, pp. A1481, 1992.

F-69) "Canine lung mechanics at very low lung volumes." G. Dechman, A.-M. Lauzon and J.H.T. Bates.

Presented at the FASEB Meeting, Anaheim, CA, April 5-9, 1992. Abstract in The FASEB Journal, 6:

part 1, pp. A1481, 1992.

F-70) "Changes in respiratory system mechanics with pleural effusion: implications for treatment." G.

Dechman, J. Sato and J.H.T. Bates. Presented at the Candian Lung Association Annual Scientific

Congress, Saskatoon, June, 1992.

F-71) "Evidence of plastoelastic behavior of canine respiratory system at very low lung volumes." G.

Dechman, A.-M. Lauzon and J.H.T. Bates. Presented at the European Respiratory Society Meeting,

Vienna, August, 1992. Abstract in The European Respiratory Journal, 5 (suppl 15): 123s, 1992.

F-72) "Dynamics of respiratory mechanical parameters during histamine challenge.." A.-M. Lauzon, G.

Dechman and J.H.T. Bates. Presented at the European Respiratory Society Meeting, Vienna, August,

1992. Abstract in the European Respiratory Journal, 5 (suppl 15): 183s, 1992.

F-73) "Understanding lung tissue mechanics in terms of mathematical models." J.H.T. Bates. Presented at

the European Respiratory Society Meeting, Vienna, August, 1992. (Invited paper)

F-74) "Mecanique pulmonaire durant des oscillations a 6 Hz." J.H.T. Bates and R. Peslin. Presented at the

34th Annual Reunion of the Club de Recherches Cliniques du Quebec, Chateau Montebello, 8-11

October 1992. Abstract in Medecine Sciences. 8 (suppl 2): pp. 15, 1992.

F-75) "Dynamique de la mecanique respiratoire." A.-M. Lauzon and J.H.T. Bates. Presented at the 34th

Annual Reunion of the Club de Recherches Cliniques du Quebec, Chateau Montebello, 8-11 October

1992. Abstract in Medecine Sciences. 8 (suppl 2): pp. 35, 1992.

F-76) "Acute response of canine lung mechanical properties following histamine injection i.v." J.H.T.

Bates. Presented at the Annual Fall Meeting of the Biomedical Engineering Society, Salt Lake City,

October 16-18, 1992. Abstract B2.2 in the conference proceedings.

F-77) "Assessment of respiratory mechanics by flow interruption and its relation to respiratory impedance."

J.H.T. Bates. Presented at the American Thoracic Society Meeting, San Francisco, May 16-19, 1993,

(invited lecture) at the minisymposium "New approaches to evaluation of lung and chest wall

function". (presented by Dr. J. Milic-Emili in my absense).

F-78) "Respiratory input impedance (8-2048 Hz) following bronchoconstriction induced by histamine

injection in dogs." A.C. Jackson, R.H. Habib, J.H.T. Bates, and B. Suki. Presented at the American

Thoracic Society Meeting, San Francisco, May 16-19, 1993. Abstract in American Review of

Respiratory Disease, 147: pp. A450, 1993.

F-79) "A stochastic model of the airway tree and its implications for bronchial hyperresponsiveness." J.H.T.

Bates. Abstract in American Review of Respiratory Disease, 147: pp. A508, 1993.

F-80) "Postobstructive pulmonary vasculopathy alters the mechanical properties of the lung parenchyma."

S.M. Kelly, J.H.T. Bates, and R.P. Michel. Presented at the American Thoracic Society Meeting, San

Francisco, May 16-19, 1993. Abstract in American Review of Respiratory Disease, 147: pp. A540,

1993.

34

F-81) "Effect of severe experimental fibrosis on lung resistance and elastance." R.P. Michel, M.P. Zwikler

and J.H.T. Bates. Presented at the American Thoracic Society Meeting, San Francisco, May 16-19,

1993. Abstract in American Review of Respiratory Disease, 147: pp. A595, 1993.

F-82) "Time course of bronchoconstriction in the dog." A.-M. Lauzon, G. Dechman and J.H.T. Bates.

Presented at Experimental Biology 93, New Orleans, 1993. Abstract in The FASEB Journal. 7: pp.

A8, 1993

F-83) "An ensemble theory for the mechanical properties of lung tissue." J.H.T. Bates and B. Suki.

Presented at Experimental Biology 93, New Orleans, 1993. Abstract in The FASEB Journal. 7: pp.

A8, 1993.

F-84) "The use of computed tomography to assess the change in canine respiratory system volume and shape

in response to acute pleural effusion." G. Dechman, M. Mishima, and J.H.T. Bates. Presented at The

Canadian Lung Association National Conference, Halifax, Nova Scotia, June 24-26, 1993.

F-85) "Age related differences in minute ventilation during halothane anesthesia in children." K. Brown, O.

Reich, and J.H.T. Bates. Anesthesiology. 79: pp. A1175, 1993.

F-86) "Viscoelastic non-linearity of lung tissue." D. Navajas, G.N. Maksym, and J.H.T. Bates. Presented at

the Annual Meeting of the European Respiratory Society, Florence, 1993. Abstract in The European

Respiratory Journal, 6 (suppl. 17): pp. 405s, 1993.

F-87) "Effects of low isoflurane concentration on respiratory mechanics." P.P. Ruiz-Neto, D. Chartrand, J.

Auler, J.H.T. Bates, and G. Dechman. Presented at the 14th International Symposium on Intensive

Care and Emergency Medicine. Brussels, March 15-18, 1994. Abstract in Supplement to Clinical

Intensive Care Medicine. 5: pp. 62, 1994.

F-88) "The time course of histamine induced bronchoconstriction and its modulation by endogenous

catecholamines and through H2 receptors." A.-M. Lauzon, G. Dechman, J.G. Martin, and J.H.T.

Bates. Presented at Experimental Biology 94, Anaheim, April 24-28, 1994. Abstract in The FASEB

Journal. 8: pp. A684, 1994.

F-89) "Following rapid changes in regional lung mechanical impedance with the alveolar capsule oscillator."

Z. Balassy, M. Mishima, and J.H.T. Bates. Presented at Experimental Biology 94, Anaheim, April

24-28, 1994. Abstract in The FASEB Journal. 8: pp. A687, 1994.

F-90) "Effects of lung volume on the acute pulmonary response to i.v. histamine using forced oscillations

through alveolar capsules in dogs." M. Mishima, Z. Balassy, and J.H.T. Bates. Presented at

Experimental Biology 94, Anaheim, April 24-28, 1994. Abstract in The FASEB Journal. 8: pp. A687,

1994.

F-91) "The effect of parallel inhomogeneity on the apparent serial distribution of airway resistance." J.H.T.

Bates. Presented at Experimental Biology 94, Anaheim, April 24-28, 1994. Abstract in The FASEB

Journal. 8: pp. A687, 1994.

F-92) "The effect of changing end-expiratory pressure on respiratory system mechanics in open- and closed-

chested anesthetized, paralyzed, and ventilated patients." G. Dechman, D. Chartrand, P. Ruis, and

J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, Boston, May 22-25,

1994. Abstract in the American Journal of Respiratory and Critical Care Medicine. 149: pp. A223,

1994.

F-93) "Nonlinear dynamic respiratory elastance in anesthetized patients." J.H.T. Bates, G. Dechman, and D.

Chartrand. Presented at the Annual Meeting of the American Thoracic Society, Boston, May 22-25,


1994.

35

F-94) "Peripheral inhomogeneity in lung tissue properties assessed by the alveolar capsule oscillator

technique." J.H.T. Bates, Z. Balassy, and M. Mishima. Presented at the Annual Meeting of the

American Thoracic Society, Boston, May 22-25, 1994. Abstract in the American Journal of

Respiratory and Critical Care Medicine. 149: pp. A537, 1994.

F-95) "Age related differences in Vi with halothane in children." K. Brown, O. Reich, and J.H.T. Bates.

Presented at the Annual Meeting of the American Thoracic Society, Boston, May 22-25, 1994.

Abstract in the American Journal of Respiratory and Critical Care Medicine. 149: pp. A692, 1994.

F-96) "Respiratory system impedance (8-2048 Hz) during bronchoconstriction induced by apnea in dogs."

R.H. Habib, B. Suki, J.H.T. Bates, and A.C. Jackson. Presented at the Annual Meeting of the

American Thoracic Society, Boston, May 22-25, 1994. Abstract in the American Journal of


F-97) "The use of computed tomography to assess change in canine respiratory system volume, shape, and

density in response to acute pleural effusion." G. Dechman, M. Mishima, and J.H.T. Bates. Presented

at the Annual Meeting of the American Thoracic Society, Boston, May 22-25, 1994. Abstract in the

American Journal of Respiratory and Critical Care Medicine. 149: pp. A1103, 1994.

F-98) "Understanding pulmonary compliance." J.H.T. Bates. Whole Body Plethysmography Symposium

(invited), SensorMedics Coorp., May 20, 1994, Back Bay Hilton, Boston, MA.

F-99) "Pulmonary mechanics and bronchoconstriction." J.H.T. Bates. Presented at the World Congress on

Medical Physics and Biomedical Engineering. Rio de Janeiro, August, 1994. (Invited state-of-the-art

presentation). Abstract in Physics in Medicine & Biology. 39a, part 2: pp. 883, 1994

F-100) "Frequency dependence of lung tissue mechanics." J.H.T. Bates. Presented at the World Congress on

Medical Physics and Biomedical Engineering. Rio de Janeiro, August, 1994. (Invited presentation).

Abstract in Physics in Medicine & Biology. 39a, part 2: pp. 885, 1994

F-101) "Measuring pulmonary mechanics at the acinar level in dogs with the alveolar capsule oscillator."

J.H.T. Bates, M. Mishima, and Z. Balassy. Presented at the FESBE Annual Meeting, Caxambu,

Brazil, August 1994. Abstract in the Conference Proceedings, pp. LX.

F-102) "Alveolar capsule oscillators identify the mechanical impedance of tiny peripheral lung regions."

J.H.T. Bates, M. Mishima, and Z. Balassy. Presented at the European Respiratory Society Meeting,

Nice, October 1-5, 1994. Abstract in The European Respiratory Journal. 7 suppl. 18: pp. 408s, 1994.

F-103) "Very localized lung response to bronchoconstrictor detected by alveolar capsule oscillator." M.

Mishima, J.H.T. Bates, Z. Balassy, and K. Kuno. Presented at the Second Joint Meeting of the

Physiological Societies of Japan, U.K. and E.I.R.E. Nagoya Symposium: Integrative Mechanisms in

Physiological Function. Nagoya, Japan, April 1-2, 1995.

F-104) "An analytic model for lung distensibility." G.N. Maksym, and J.H.T. Bates. Presented at the

American Thoracic Society Meeting, Seattle, May 1995. Abstract in the American Journal of


F-105) "Stochastic distributions of properties in a branching model of the lung. C.W. Thorpe, and J.H.T.

Bates. Presented at the American Thoracic Society Meeting, Seattle, May 1995. Abstract in the


F-106) "Nonlinear rat pulmonary mechanics identification." G.N. Maksym, T.F. Schuessler, and J.H.T. Bates.

Presented at the American Thoracic Society Meeting, Seattle, May 1995. Abstract in the American

Journal of Respiratory and Critical Care Medicine. 151: pp. A116, 1995.

F-107) "Simulation of local lung impedance measured by capsule oscillator using asymmetrical branching

model." M. Mishima, K. Kuno, Z. Balassy, and J.H.T. Bates. Presented at the American Thoracic

36

Society Meeting, Seattle, May 1995. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 151: pp. A117, 1995.

F-108) "True and measured intrinsic PEEP in the presence of expiratory effort." T.F. Schuessler, and J.H.T.

Bates. Presented at the American Thoracic Society Meeting, Seattle, May 1995. Abstract in the


F-109) "Effects of expiratory effort and cardiogenic oscillations on the measurement of work of breathing."

T.F. Schuessler, and J.H.T. Bates. Presented at the American Thoracic Society Meeting, Seattle, May


1995.

F-110) "Weaning ventilated patients used fuzzy logic." T. Nemoto, C.W. Thorpe, and J.H.T. Bates. Presented

at the American Thoracic Society Meeting, Seattle, May 1995. Abstract in the American Journal of


F-111) "The temporal dynamics of acute induced bronchoconstriction." Presented at the Biomedical

Simulations Resource short course on Bioengineering Approaches to Pulmonary Physiology and

Medicine. Seattle, May 20, 1995.

F-112) "Suppression of cardiogenic oscillations on esophageal pressure: effect on measurement of intrinsic

PEEP." T.F. Schuessler, C.A. Volta, P. Goldberg, R.E. Kearney, and J.H.T. Bates. Presented at the

Annual Meeting of the Royal Canadian College of Physicians and Surgeons, Montreal, September

1995. Abstract in Clinical and Investigative Medicine. 18: pp. B25, 1995.

F-113) “The effect of treatment delays on local control by radiotherapy.” W.J. Mackillop, JHT Bates, B.

O’Sullivan, and H.R. Withers. Presented at the Annual Meeting of the Royal Canadian College of

Physicians and Surgeons, Montreal, September 1995. Abstract in Clinical and Investigative Medicine.

18: pp. B131, 1995.

F-114) "A computer model of human pulmonary ventilation and gas exchange suitable for calculating

ventilatory uptake of airborne pollutants." C.W. Thorpe, J.H.T. Bates, and J.A. Leech. Presented at

the Annual Meeting of the Royal Canadian College of Physicians and Surgeons, Montreal, September

1995. Abstract in Clinical and Investigative Medicine. 18: pp. B141, 1995.

F-115) "The one-dimensional Fourier transform in physiological signal analysis." Invited paper for mini-

symposium on The Role of the Fourier Transform in Biomedical Engineering, presented at the 17th

Annual International Meeting of the I.E.E.E. Engineering in Medicine and Biology, Montreal,

Quebec, Canada, September 1995.

F-116) "Pulmonary mechanics in dogs with chronic unilateral pulmonary artery ligation." S.M. Kelly, J.H.T.

Bates, and R.P. Michel. Presented at the 1995 Annual Fall Meeting of the Biomedical Engineering

Society, Boston, October, 1995. Abstract in Annals of Biomedical Engineering. 23 (suppl 1), pp. S-

11, 1995.

F-117) "A nonlinear distributed model of lung tissue elasticity." J.H.T. Bates, and G.N. Maksym. Presented

at the 1995 Annual Fall Meeting of the Biomedical Engineering Society, Boston, October, 1995.

Abstract in Annals of Biomedical Engineering. 23 (suppl 1), pp. S-11, 1995.

F-118) "Acute time-course of induced bronchoconstriction in rats: significance of central airway shunting."

J.H.T. Bates, T.F. Schuessler, C. Dolman, and D.H. Eidelman. Presented at the 1995 Annual Fall

Meeting of the Biomedical Engineering Society, Boston, October, 1995. Abstract in Annals of

Biomedical Engineering. 23 (suppl 1), pp. S-15, 1995.

F-119) "Recent advances in the study of lung mechanics." (Invited plenary talk). J.H.T. Bates. Presented at

the IEEE Engineering and Physics in Medicine Meeting, Queenstown, New Zealand, November 20-

37

24, 1995. Proceedings pp. 164.

F-120) "Ozone uptake in a multi-compartment ventilation model." C.W. Thorpe, J.H.T. Bates and J.A. Leech.

Presented at the Annual Meeting of the American Thoracic Society, New Orleans, May 11-15, 1996.

Abstract in American Journal of Respiratory and Critical Care Medicine. 153: pp. A303, 1996.

F-121) "Model-based analysis of patient-ventilator desynchronization during pressure support ventilation."

T.F. Schuessler and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society,

New Orleans, May 11-15, 1996. Abstract in American Journal of Respiratory and Critical Care

Medicine. 153: pp. A372, 1996.

F-122) "Assessment of a fuzzy logic algorithm for weaning patients from mechanical ventilation." T.

Nemoto, C.W. Thorpe, S. Dial and J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, New Orleans, May 11-15, 1996. Abstract in American Journal of Respiratory and

Critical Care Medicine. 153: pp. A607, 1996.

F-123) "Time-course of pulmonary mechanics following vagal stimulation at different lung volumes." N.

Shinozuka, T.J. Nemoto and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic

Society, New Orleans, May 11-15, 1996. Abstract in American Journal of Respiratory and Critical

Care Medicine. 153: pp. A744, 1996.

F-124) "Measurement of frequency and lung volume dependence of respiratory mechanics in the mouse." T.F.

Schuessler, C. Dolman, D.H. Eidelman and J.H.T. Bates. Presented at the Annual Meeting of the

American Thoracic Society, New Orleans, May 11-15, 1996. Abstract in American Journal of


F-125) "Resistance characteristics of seven different in-line pulmonary function testing bacterial filters." P.

Vallinis, J.H.T. Bates, C. Darauay, W.J. Gibbons and R.D. Levy. Presented at the Annual Meeting of

the American Thoracic Society, New Orleans, May 11-15, 1996. Abstract in American Journal of


F-126) "Estimation of airway resistance in tracheal-banded rats." G. Dechman, T.F. Schuessler and J.H.T.

Bates. Presented at the Annual Meeting of the American Thoracic Society, New Orleans, May 11-15,

1996. Abstract in American Journal of Respiratory and Critical Care Medicine. 153: pp. A747, 1996.

F-127) "Lung volume dependence of bronchial responsiveness in rats." M. Ahmadi, T.F. Schuessler, C.

Dolman, D.H. Eidelman and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic

Society, New Orleans, May 11-15, 1996. Abstract in American Journal of Respiratory and Critical


F-128) "Distributed fiber properties in modelling static lung tissue elasticity". G.N. Maksym and J.H.T. Bates.


Abstract in American Journal of Respiratory and Critical Care Medicine. 153: pp. A863, 1996.

F-129) "The volume dependence of airway responsiveness: geometric considerations". C. W. Thorpe and

J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, New Orleans, May

11-15, 1996. Abstract in American Journal of Respiratory and Critical Care Medicine. 153: pp. A876,

1996.

F-130) "An entropy model of lung tissue rheology." J.H.T. Bates. Presented at the Annual Meeting of the

Biomedical Engineering Society, Penn State University, October 3-6, 1996. Abstract in Annals of

Biomedical Engineering. 24, suppl 1: pp. S-13, 1996.

F-131) "Confocal microscopic measurements of the parenchymal strain field due to constriction in adjacent

airways." A. Adler, E.A. Cowley, D. Eidelman and J.H.T. Bates. Presented at the Annual Meeting of

the Biomedical Engineering Society, Penn State University, October 3-6, 1996. Abstract in Annals of

38


F-132) "Model analysis of airway contracting against parenchymal attachments." J.H.T. Bates, A. Adler and

D.H. Eidelman. Presented at the Annual Meeting of the Biomedical Engineering Society, Penn State

University, October 3-6, 1996. Abstract in Annals of Biomedical Engineering. 24 suppl 1: pp. S-17,

1996.

F-133) "A nonlinear model of lung parenchyma disease." G.N. Maksym and J.H.T. Bates. Presented at the

Annual Meeting of the Biomedical Engineering Society, Penn State University, October 3-6, 1996.

Abstract in Annals of Biomedical Engineering. 24, suppl 1: pp. S-17, 1996.

F-134) "Hysteresivity and heterogeneity." C.W. Thorpe and J.H.T. Bates. Presented at the Annual Meeting of

the Biomedical Engineering Society, Penn State University, October 3-6, 1996. Abstract in Annals of


F-135) “Changes in respiratory impedance with i.v. methacholine in the mouse: reproducibiity of repeated

challenges.” R.F.M. Gomes, E. Minshall, T.F. Schuessler, D.H. Eidelman, and J.H.T. Bates.

Presented at the Annual Meeting of the American Thoracic Society, San Francisco, May 17-21, 1997.


F-136) “An adaptive filter to reduce the adverse effects of cardiogenic oscillations on measured intrinsic

PEEP.” T.F. Schuessler, S.B. Gottfried, P. Goldberg, R.E. Kearney, and J.H.T. Bates. Presented at the

Annual Meeting of the American Thoracic Society, San Francisco, May 17-21. Abstract in the


F-137) “Monitoring dynamic hyperinflation in dogs with electrical impedance tomography.” A. Adler, N.

Shinozuka, R. Guardo, Y. Berthiaume, and J.H.T. Bates. Presented at the Annual Meeting of the

American Thoracic Society, San Francisco, May 17-21. Abstract in the American Journal of


F-138) “Phenotypic characterization of methacholine responsiveness in inbred strains of mouse.” E.M.

Minshall, R.F.M. Gomes, T.F. Schuessler, J.H.T. Bates, and D.H. Eidelman. Presented at the Annual

Meeting of the American Thoracic Society, San Francisco, May 17-21. Abstract in the American


F-139) “A computer-controlled high-bandwidth mechanical ventilator for the intensive care unit: design and

construction.” M. Ahmadi, T.F. Schuessler, and J.H.T. Bates. Presented at the Annual Meeting of the

American Thoracic Society, San Francisco, May 17-21. Abstract in the American Journal of


F-140) “The effect of transient lung volume change on pulmonary mechanics following methacholine

injection.” N. Shinozuka, J.-P. Lavoie, J.G. Martin, and J.H.T. Bates. Presented at the Annual

Meeting of the American Thoracic Society, San Francisco, May 17-21, 1997. Abstract in the


F-141) “Dynamic lung constriction in rats before and after pulmonary edema.” K.R. Lutchen, B. Suki, T.

Schuessler, R. Gomes, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic

Society, San Francisco, May 17-21. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 155: pp. A859, 1997.

F-142) “Mechanical impedance of the respiratory system in guniea pigs.” R. Gomes, X.X. Yang, K.A.L.

Lundblad, T.F. Schuessler, J.G. Martin, and J.H.T. Bates. Presented at the Annual Meeting of the

American Thoracic Society, San Francisco, May 17-21, 1997. Abstract in the American Journal of


F-143) “Measurement of parenchymal strain due to airway contraction in a rat lung explant system.” A.Adler,

39

E.A. Cowley, J.H.T. Bates, and D.H. Eidelman. Presented at the Annual Meeting of the American

Thoracic Society, San Francisco, May 17-21. Abstract in the American Journal of Respiratory and


F-144) “Nonparametric block structured models for lung tissue strips.” G.N. Maksym, R.E. Kearney, and

J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, San Francisco, May

17-21. Abstract in the American Journal of Respiratory and Critical Care Medicine. 155: pp. A862,

1997.

F-145) “A computer model of the mouse lung.” J.H.T. Bates, P.D. Sly, and C.G. Irvin. Presented at the

European Respiratory Society Annual Congress, Berlin, 20-24 September, 1997. Abstract in the

European Respiratory Journal, pp. 24s, 1997.

F-146) “Development of a method for measuring low-frequency forced oscillation in mice.” P.D. Sly, C.G.

Irvin, and J.H.T. Bates. Presented at the European Respiratory Society Annual Congress, Berlin, 20-

24 September, 1997. Abstract in the European Respiratory Journal, pp. 48s, 1997

F-147) “Mice exhibit strain-dependent differences in respiratory mechanics assessed with forced oscillations.”

C.G. Irvin, J.H.T. Bates, J. Honour, and P.D. Sly. Presented at the European Respiratory Society

Annual Congress, Berlin, 20-24 September, 1997. Abstract in the European Respiratory Journal, pp.

287s, 1997.

F-148) “Phenotypic characterization of methacholine responsiveness in inbred strains of mice. E.M. Minshall,

R.F.M. Gomes, T.F. Schuessler, J.H.T. Bates, and D.H. Eidelman. Presented at the Annual Meeting of

the Royal College of Physicians and Surgeons of Canada, 1997. Abstract in Clinical and Investigative

Medicine. 20, August supplement: pp. S100, 1997.

F-149) “A fuzzy logic based decision making system for automatic control of pressure support ventilation in

COPD patients.” G.E. Hatzakis, S. Dial, R. Olivenstein and J.H.T. Bates. Presented at the 2nd

Mediterranean Congress on Thoracic Diseases, March 4-7, Athens, Greece. Conference proceedings

page 10.

F-150) “Assessment of respiratory mechanics in patients.” J.H.T. Bates. Presented at the 19th Annual

Scientific Meeting of the Australian and New Zealand Society of Respiratory Science, Adelaide,

Australia, 13-15 March, 1998. (Invited talk)

F-151) “The mechanical changes in the lung during induced bronchoconstriction.” J.H.T. Bates. Presented at

the 19th Annual Scientific Meeting of the Australian and New Zealand Society of Respiratory

Science, Adelaide, Australia, 13-15 March, 1998. (Invited talk)

F-152) “Physiological effects of lung volume reduction surgery.” J.H.T. Bates. Presented at the 19th Annual

Scientific Meeting of the Australian and New Zealand Society of Respiratory Science, Adelaide,

Australia, 13-15 March, 1998. (Invited talk)

F-153) “Maturational changes in respiratory mechanics in the rat.” R. Gomes, F. Shardonofsky, D.H.

Eidelman, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society,

Chicago, April 24-29, 1998. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 157: pp. A79, 1998.

F-154) “Preferential pathways of force transmission in a randomly distributed model of lung tissue.” G.N.

Maksym, J.J. Fredberg, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic

Society, Chicago, April 24-29, 1998. Abstract in the American Journal of Respiratory and Critical


F-155) “Respiratory mechanics in the guinea pig: effects of frequency and PEEP.” R.F.M. Gomes, X.X.

Yang, K.A.L. Lundblad, P. Juhlin, J.G. Martin, and J.H.T. Bates. Presented at the Annual Meeting of

40

the American Thoracic Society, Chicago, April 24-29, 1998. Abstract in the American Journal of


F-156) “Partitioning respiratory mechanics in the rat: matching lung volumes between closed and open chest

conditions.” T. Hirai, M. Ahmadi, R.F.M. Gomes, and J.H.T. Bates. Presented at the Annual Meeting

of the American Thoracic Society, Chicago, April 24-29, 1998. Abstract in the American Journal of


F-157) “Estimating respiratory mechanics in the presence of inspiratory flow limitation.” E. Bijaoui, S. Tuck,

J. Remmers, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society,

Chicago, April 24-29, 1998. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 157: pp. A312, 1998.

F-158) “Effect of time-varying smooth muscle load on airway responsiveness in the rat.” N. Shinozuka, T.

Hirai, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, Chicago,

April 24-29, 1998. Abstract in the American Journal of Respiratory and Critical Care Medicine. 157:

pp. A516, 1998.

F-159) “Model analysis of increased airway-parenchymal interdependence due to parenchymal tortion in the

airway vicinity.” A. Adler, C.G. Irvin, J.H.T. Bates, and D.H. Eidelman. Presented at the Annual

Meeting of the American Thoracic Society, Chicago, April 24-29, 1998. Abstract in the American


F-160) “Micromechanical modelling of the volume dependence of airway-parenchymal interdependence.” A.

Adler, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, Chicago,

April 24-29, 1998. Abstract in the American Journal of Respiratory and Critical Care Medicine. 157:

pp. A518, 1998.

F-161) “Characteristics of a computer controlled high-frequency ventilator for the intensive care unit.” M.

Ahmadi, T.F. Schuessler, and J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, Chicago, April 24-29, 1998. Abstract in the American Journal of Respiratory and


F-162) “Power law distribution of low attenuation areas on chest-ray CT in patients with chronic obstructive

pulmonary disease.” M. Mishima, B. Suki, T. Hirai, H. Sakai, Y. Nakano, S. Muro, K. Nishimuro, Y.

Oku, K. Chin, M. Ohi, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic

Society, Chicago, April 24-29, 1998. Abstract in the American Journal of Respiratory and Critical


F-163) “The effect of airway-parenchymal interactions on bronchial responsiveness.”. J.H.T. Bates and A.

Adler. Presented at the Annual Fall Meeting of the Biomedical Engineering Society, Cleveland,

October 10-13, 1998. Abstract in Annals of Biomedical Engineering, 26 suppl. 1, pp. S-46, 1998.

F-164) “Weaning control of patients under assisted ventilation in the ICU through an expert system.” G.E.

Hatzakis, S. Dial, R. Olivenstein and J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, San Diego, April 23-28, 1999. Abstract in the American Journal of Respiratory and


F-165) “Measuring pressure and flow delivered by a computer-controlled mechanical ventilator for the

intensive care unit.” M. Ahmadi and J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, San Diego, April 23-28, 1999. Abstract in the American Journal of Respiratory and


F-166) “The effect of inspiratory volume load on the respiratory impedance after methacholine challenge in

the rat.” T. Hirai and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic

Society, San Diego, April 23-28, 1999. Abstract in the American Journal of Respiratory and Critical

41


E-167) “Lung and chest wall mechanics in relation to lung volume in the mouse.” T. Hirai and J.H.T. Bates.

Presented at the Annual Meeting of the American Thoracic Society, San Diego, April 23-28, 1999.


E-168) “Oscillatory respiratory mechanics in the mouse: comparing results obtained with the wavetube and

the flexiVent.” G.L. Hall, Z. Hantos, Y. Ueda, J.H.T. Bates and P.D. Sly. Presented at the Annual

Meeting of the American Thoracic Society, San Diego, April 23-28, 1999. Abstract in the American


E-169) “Assessment of respiratory mechanics using cardiogenic oscillations.” E.L. Bijaoui and J.H.T. Bates.

Presented at the Annual Meeting of the American Thoracic Society, San Diego, April 23-28, 1999.


E-170) “Comparative respiratory system mechanics of mice, rats and guinea pigs.” R.F.M. Gomes and J.H.T.

Bates. Presented at the Annual Meeting of the American Thoracic Society, San Diego, April 23-28,


1999.

E-171) “Measurement of respiratory mechanics during sleep in patients with sleep-disordered breathing.” E.L.

Bijaoui, V. Champagne, R.J. Kimoff and J.H.T. Bates. Presented at the Annual Meeting of the

American Thoracic Society, Toronto, May 5-10, 2000. Abstract in the American Journal of


E-172) “Bronchoconstriction-induced curvilinearity of the lung pressure-volume relationship in the mouse.”

S.S. Wagers, J.H.T. Bates and C.G. Irvin. Presented at the Annual Meeting of the American Thoracic

Society, Toronto, May 5-10, 2000. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 161: pp. A272, 2000.

E-173) “Airway and tissue mechanics in a murine model of asthma: alveolar capsules vs. Forced oscillations.”

S. Tomioka, J.H.T. Bates, J. Woodcock-Mitchell and C.G. Irvin. Presented at the Annual Meeting of

the American Thoracic Society, Toronto, May 5-10, 2000. Abstract in the American Journal of


E-174) “A fuzzy logic controller for pressure support ventilation in COPD patients.” G. Hatzakis, R.

Olivenstein and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society,

Toronto, May 5-10, 2000. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 161: pp. A384, 2000.

E-175) “Measurement of regional lung mechanics in humans using forced oscillations through the wedged

bronchocscope.” D.A. Kaminsky, J.H.T. Bates, S. Tomioka, M. Lynn and C.G. Irvin. Presented at the

Annual Meeting of the American Thoracic Society, Toronto, May 5-10, 2000. Abstract in the


E-176) “Changes in respiratory mechanics in the Pallid mouse after chronic exposure to cigarette smoke.” Y.

Takubo, A. Guerassimov, A. Triantafillopoulos, H. Ghezzo, J.H.T. Bates and M.G. Cosio. Presented

at the Annual Meeting of the American Thoracic Society, Toronto, May 5-10, 2000. Abstract in the


E-177) “Comparative respiratory system mechanics in rodents.” R.F.M. Gomes, R. Ramchandani, X. Shen,

R.S. Tepper, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society,


Medicine. 161: pp. A688, 2000.

E-178) “Respiratory mechanics and lung development in the rat.” R.F.M. Gomes, F. Shardonofsky, D.H.

42

Eidelman and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society,


Medicine. 161: pp. A688, 2000.

E-179) “Comparison of respiratory mechanics in mice before and after death.” Y. Takubo, T. Hirai, R.F.M.

Gomes, H. Ghezzo, M.G. Cosio and J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, Toronto, May 5-10, 2000. Abstract in the American Journal of Respiratory and


F-180) “A model of nitric oxide (NO) dynamics in the airway.” R.A. Dweik, D. Laskowski, J.H.T. Bates and

S.C. Erzurum.Presented at the Annual Meeting of the American Thoracic Society, Toronto, May 5-10,


2000.

F-181) “Assessment of respiratory pattern in extremely low birth-weight pre-term infants.” G. Hatzakis, G.

Mesiano, J.H.T. Bates, and G.M. Davis.Presented at the Annual Meeting of the American Thoracic

Society, Toronto, May 5-10, 2000. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 161: pp. A801, 2000.

F-182) “Inflammation causes significant differences in tissue mechanics in mice: importance of genetic

strain.” S. Tomioka, J.H.T. Bates and C.G. Irvin.Presented at the Annual Meeting of the American



F-183) “The prevalence of post-sigh apnea in infnats at risk for post-operative apnea.” K. Brown and J. Bates.

Submitted for presentation at the CAS World Congress.

F-184) “Post sigh apnea represents the majority of central apnea in infants at risk for post-operative apnea.”

K. Brown and J.H.T. Bates. Submitted for presentation at the APA Meeting, March 2000.

F-185) “A computational model to predict the impact of airway wall morphometry an lung function in mature

and immature lungs.” N. Tgavalekos, R. Tepper, J.H.T. Bates and K. Lutchen. Presented at the

Annual Fall Meeting of the Biomedical Engineering Society, Seattle, WA, October 12-14, 2000.

Abstract in Annals of Biomedical Engineering, 80 (suppl 1); S-49, 2000.

F-186) “Assessment of respiratory function through anthropomorphic characteristics in caucasian, black and

Hindi Children.” G.E. Hatzakis, D. Desjardins, P. Del Sonno, J. Ficara, J.H.T. Bates and G.M. Davis.

Presented at the American Thoracic Society Meeting, May 18-23, 2001, San Francisco. Abstract in

the American Journal of Respiratory and Critical Care Medicine. 163: pp. A371, 2001.

F-187) “An algorithm for the automated detection of thoracoabdominal asynchrony”. K. Brown and J.H.T.

Bates. Presented at the American Thoracic Society Meeting, May 18-23, 2001, San Francisco.


F-188) “Lung mechanics before and after caffeine citrate in extremely low birth weight infants.” G. Hatzakis,

D. Fitzgerald, G. Mesiano, J.H.T. Bates, D. Willis and G.M. Davis. Presented at the American

Thoracic Society Meeting, May 18-23, 2001, San Francisco. Abstract in the American Journal of


F-189) “Airway and lung tissue mechanics following direct instillation of bronchoactive agents into a wedged

subsegment in asthma.” D.A. Kaminsky, C.G. Irvin, M. Lynn, H.T. Moriya and J.H.T. Bates.

Presented at the American Thoracic Society Meeting, May 18-23, 2001, San Francisco. Abstract in the


F-190) “A morphometric modeling study to predict structural and mechanical factors associated with

excessive airway narrowing in immature lungs. N. Tgavalekos, R. Tepper, J.H.T. Bates and K.R.

43

Lutchen. Presented at the American Thoracic Society Meeting, May 18-23, 2001, San Francisco.


F-191) "Fuzzy Logic and Mechanical Ventilation of COPD Patients." G.E. Hatzakis, R. Olivenstein and

J.H.T. Bates. Presented at the American Medical Informatics Association Annual Meeting,

Washington DC, November 6 2001. Abstract in the Journal of the American Medical Informatics

Association, Suppl 2001:923.

F-192) “A theoretical model of the transient effects of a deep inflation on lung recruitment and

derecruitement.” J.H.T. Bates. Presented at the American Thoracic Society Meeting, Atlanta, May 17-

22, 2002. Abstract in the American Journal of Respiratory and Critical Care Medicine. 165: A164,

2002.

F-193) “Continuous monitoring of lung mechanics in mechanically ventilate patients: variability and

reproducibility.” J.H.T. Bates, S. Wagers, H.T. Moriya and M. Young. Presented at the American

Thoracic Society Meeting, Atlanta, May 17-22, 2002. Abstract in the American Journal of Respiratory

and Critical Care Medicine. 165: A180, 2002.

F-194) “Peripheral lung hyperresponsiveness assessed through the wedged bronchoscope by local forced

oscillations.” D.A. Kaminsky, C.G. Irvin, H.T. Moriya, M. Lynn, S.L. Lang, and J.H.T. Bates.

Presented at the American Thoracic Society Meeting, Atlanta, May 17-22, 2002. Abstract in the

American Journal of Respiratory and Critical Care Medicine. 165: A255, 2002.

F-195) “The transient nature of tissue elastance following deep inhalation recruitment maneuvers in the

mouse.” G. Allen, L.K.A. Lundblad and J.H.T. Bates. Presented at the American Thoracic Society

Meeting, Atlanta, May 17-22, 2002. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 165: A374, 2002.

F-196) “Complex impedance of intact lung and tissue strips in C57/Bl6 mice.” A. Fust, J.H.T. Bates, and

M.S. Ludwig. Presented at the American Thoracic Society Meeting, Atlanta, May 17-22, 2002.

Abstract in the American Journal of Respiratory and Critical Care Medicine. 165: A455, 2002.

F-197) “Unrestrained plethysmography in mice: Boyle’s law versus gas conditioning.” L.K.A. Lundblad, M.

Persson and J.H.T. Bates. Presented at the American Thoracic Society Meeting, Atlanta, May 17-22,

2002. Abstract in the American Journal of Respiratory and Critical Care Medicine. 165: A455, 2002.

F-198) “A new method for assessing lung mechanics using unrestrained plethysmography in mice.” L.K.A.

Lundblad, M. Persson and J.H.T. Bates. Presented at the American Thoracic Society Meeting, Atlanta,

May 17-22, 2002. Abstract in the American Journal of Respiratory and Critical Care Medicine. 165:

A455, 2002.

F-199) “Transforming growth factor beta (TGF-β) plays an anti-inflammatory role in a murine airway

inflammation model. L.M. Rinaldi, E.F. Jaffe, J.H.T. Bates and C.G. Irvin. Presented at the American

Thoracic Society Meeting, Atlanta, May 17-22, 2002. Abstract in the American Journal of Respiratory


F-200) “Reduced thoracic gas volume in a mouse model of acute lung injury.” L.K.A. Lundblad, G. Allen,

C.G. Irvin and J.H..T. Bates. Presented at the American Thoracic Society Meeting, Atlanta, May 17-


2002.

F-201) “Alterations in the time course of bronchoconstriction in mice with airway inflammation.” S. Wagers,

L.K.A. Lundblad, M. Persson, C.G. Irvin and JHT Bates. Presented at the American Thoracic Society


Medicine. 165: A801, 2002.

44

F-202) “Treating ALI/ARDS: has new science changed practice?” M. Young, H. Manning, D. Wilson, S.

Mette, R. Riker, J.H.T. Bates, J. Leiter, P. Parsons. Presented at the American Thoracic Society


Medicine. 165:, 2002.

F-203) “Role of fibrin in determining airway closure.” S. Wagers, R. Norton, J.H.T. Bates, and C.G. Irvin

Asthma in the New Millennium: Aspen Lung Conference 2002. Chest. 123: 362S - 363S, 2003.

F-204) “Peripheral lung responsiveness assessed by forced oscillations through the wedged bronchoscope.”

D.A. Kaminsky, C.G. Irvin, H.T. Moriya, M. Lynn., S. Lang, and J.H.T. Bates. Asthma in the New

Millennium: Aspen Lung Conference 2002. Chest. 123: 363S, 2003.

F-205) “Importance of measuring peripheral lung mechanics in mouse models.” J.H.T. Bates. Presented at the

4th International Congress of Pathophysiology. Budapest, Hungary, July 1-5, 2002. Abstract in Acta

Physiologica Hungarica. 89: pp. 237, 2002.

F-206) “Effects of vagotomy on lung mechanics in mice.” M. Persson, L.K.A. Lundblad, C.G. Irvin, P.

Wollmer, and J.H.T. Bates. Presented at the European Respiratory Society Annual Congress,

Stockholm, September 14-18, 2002. Abstract in the European Respiratory Journal. 20, Suppl. 38:

105s, 2002.

F-207) “Computer modelling of peripheral lung impedance: roles of airway wall compliance and mass.” D.A.

Kaminsky, C.G.Irvin, L.K.A. Lundblad, M. Lynn, S. Lang, and J.H.T. Bates. Presented at the

American Thoracic Society Meeting, Seattle, May 16-21, 2003. Abstract in the American Journal of

Respiratory and Critical Care Medicine. 167: A139, 2003.

F-208) “Airway resistance during spontaneous breathing in humans. L.K.A Lundblad, J.H.T. Bates, and D.A.

Kaminsky. Presented at the American Thoracic Society Meeting, Seattle, May 16-21, 2003. Abstract

in the American Journal of Respiratory and Critical Care Medicine. 167: A419, 2003.

F-209) “Thoracic gas volume measurements in paralyzed mice.” L.K.A. Lundblad, C.G. Irvin, and J.H.T.

Bates. Presented at the American Thoracic Society Meeting, Seattle, May 16-21, 2003. Abstract in the


F-210) “3-D histological analysis of mouse lung airway structure.” J.A. Thompson-Figueroa, S. Wagers, S.

Bentil, and J.H.T. Bates. Presented at the American Thoracic Society Meeting, Seattle, May 16-21,


F-211) “Effect of aerosolized fibrinogen on lung elastance and derecruitment.” G.B. Allen, S.S. Wagers, R.

Norton, J.H.T. Bates. Presented at the American Thoracic Society Meeting, Seattle, May 16-21, 2003.


F-212) “Dissociation between alveolar neutrophils and lung mechanics in a mouse model of lung injury.”

G.B. Allen and J.H.T. Bates. Presented at the American Thoracic Society Meeting, Seattle, May 16-


2003.

F-213) “Computer model of bronchial responsiveness in mice.” J.H.T. Bates, S. Wagers, L.K.A. Lundblad,

and C.G. Irvin. Presented at the American Thoracic Society Meeting, Seattle, May 16-21, 2003.


F-214) “Respiratory therapists target ventilation rather than peak pressure during manual ventilation.” M.

Turki, M.P. Young, S. Wagers, and J.H.T. Bates. Presented at the American Thoracic Society

Meeting, Seattle, May 16-21, 2003. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 167: A911, 2003.

F-215) “Power-laws in nature – where do they come from?” J.H.T. Bates. Presented at the Annual Meeting of

45

the Biomedical Engineering Society, Nashville, October 1-4, 2003. Proceedings talk no. 12.1.1.

F-216) “Computational modeling of mouse lung mechanics.” J.H.T. Bates, S. Wagers, L.K.A. Lundblad, and

C.G. Irvin. Presented at the Annual Meeting of the Biomedical Engineering Society, Nashville,

October 1-4, 2003. Proceedings talk no. 12.2.4.

F-217) ”Modeling the dynamics of lung derecruitment in a mouse model of lung injury.” J.H.T. Bates and

G.B. Allen. Presented at the Annual Meeting of the Biomedical Engineering Society, Nashville,

October 1-4, 2003. Proceedings talk no. 12.5.2.

F-218) “Mouse strain determines the degree and regional pattern of cationic protein induced airway

hyperresponsiveness.” L.M. Rinaldi, S.W. Wagers, R.J. Norton, J.H.T. Bates, and C.G. Irvin.

Presented at the American Thoracic Society Meeting, Orlando, May, 2003. Abstract in the American

Journal of Respiratory and Critical Care Medicine. 169: A294, 2004.

F-219) “Plethysmographic measurements of lung volume in paralyzed mice.” L.K.A. Lundblad, J. Thompson-

Figueroa, T. Leclair, C.G. Irvin and J.H.T. Bates. Presented at the American Thoracic Society

Meeting, Orlando, May, 2003. Abstract in the American Journal of Respiratory and Critical Care

Medicine. 169: A294, 2004.

F-220) “Delays in transfer to the ICU: Do they really matter?” M. Young, J.H.T. Bates, and P. Parsons.

Presented at the American Thoracic Society Meeting, Orlando, May, 2003. Abstract in the American


F-221) “Repeated deep inflations reduce injury during low tidal volume ventilation in mice.” G.B. Allen and

J.H.T. Bates. Presented at the American Thoracic Society Meeting, Orlando, May, 2003. Abstract in

the American Journal of Respiratory and Critical Care Medicine. 169: A721, 2004.

F-222) “Caloric restriction and subsequent re-feeding results in reversible changes in lung structure and

function in mice.” T. Beckett, L.K.A. Lundblad, J.H.T. Bates, M. Stern, and D.J. Weiss. Presented at

the American Thoracic Society Meeting, Orlando, May, 2003. Abstract in the American Journal of


F-223) “Making the structure-function link in mouse models of lung hyperresponsiveness.” Invited

presentation and co-chair at symposium C79 – Hyperresponsiveness of the lung: from molecules to the

whole organ. Presented at the American Thoracic Society Meeting, Orlando, May, 2004.

F-224) “The role of the smooth muscle force-velocity relationship on the dynamics of bronchoconstriction.”

J.H.T. Bates and A.-M. Lauzon. Presented at the Annual Fall Meeting of the Biomedical Engineering

Society, Philadelphia, October 13-16, 2004. Proceedings talk no. 384.

F-225) “Noninvasive assessment of lung function by unrestrained video-assisted plethysmography.” J.

Thompson-Figueroa, L.K.A. Lundblad, C.G. Irvin and J.H.T. Bates. Presented at the Annual Fall

Meeting of the Biomedical Engineering Society, Philadelphia, October 13-16, 2004. Proceedings talk

no. 1221.

F-226) “Lung mechanical dysfunction in acid-injured mice fluctuates over the first 48 hours.” G.B. Allen, T.

Leclair, and J.H.T. Bates. Presented at the American Thoracic Society Meeting, San Diego, May 20-

25, 2005. Abstract in the Proceedings American Thoracic Society. Volume 2, Abstract Issue: A149,

2005.

F-227) “Lung volume is reduced by caloric restriction in mice.” T. Beckett, L.K.A. Lundblad, D.S. Lala, R.

Loi, M.J. Sullivan, G.C. Davies, J.H.T. Bates, and D.J. Weiss. Presented at the American Thoracic

Society Meeting, San Diego, May 20-25, 2005. Abstract in the Proceedings American Thoracic

Society. Volume 2, Abstract Issue: A286, 2005.

F-228) “TNF- in lung disease: a single cause behind a complex phenotype”. L.K.A. Lundblad, J.

46

Thompson-Figueroa, T. Leclair, M.E. Poynter, C.G. Irvin, and J.H.T. Bates. Presented at the

American Thoracic Society Meeting, San Diego, May 20-25, 2005. Abstract in the Proceedings

American Thoracic Society. Volume 2, Abstract Issue: A288, 2005.

F-229) “Structural validation by computerized tomography (CT) of heterogeneous airway narrowing used in

modeling lung impedance in asthma.” D.A. Kaminsky, L. Lundblad, J. Thompson-Figueroa, M.

Sullivan, J. Klein, S. Lang, F. Flynn, J.H.T. Bates, and C.G. Irvin. Presented at the American Thoracic



F-230) “Imaging lung tissue strain by elastography using computerized tomography.” D.A. Kaminsky, R.

Ketchem, D. Pechenick, J. Klein, F. Flynn, J. Thompson-Figueroa, S. Lang, C.G. Irvin, J.H.T. Bates,

and J. Frolik. Presented at the American Thoracic Society Meeting, San Diego, May 20-25, 2005.

Abstract in the Proceedings American Thoracic Society. Volume 2, Abstract Issue: A492, 2005.

F-231) “Deep inhalation fails to reduce respiratory system impedance following methacholine-induced

bronchoconstriction when asthmatic subjects are supine.” D.A. Kaminsky, L. Lundblad, J.

Thompson-Figueroa, S. Lang, J.H.T. Bates, and CG Irvin. Presented at the American Thoracic Society

Meeting, San Diego, May 20-25, 2005. Abstract in the Proceedings American Thoracic Society.

Volume 2, Abstract Issue: A563, 2005.

F-232) “Airway closure during bronchoconstriction in mice confirmed with micro-CT.” L.K.A. Lundblad,

G.B. Allen, J. Thompson-Figueroa, and J.H.T. Bates. Presented at the American Thoracic Society

Meeting, San Diego, May 20-25, 2005. Abstract in the Proceedings American Thoracic Society.

Volume 2, Abstract Issue: A564, 2005.

F-233) “Allergic inflammation, cationic protein, and strain variation produce different patterns of airway

hyperresponsiveness in the mouse.” S.S. Wagers, R.J. Norton, L.M. Rinaldi, C.G. Irvin, and J.H.T.

Bates. Presented at the American Thoracic Society Meeting, San Diego, May 20-25, 2005. Abstract in

the Proceedings American Thoracic Society. Volume 2, Abstract Issue: A581, 2005.

F-234) “Peripheral lung inflammation and enhanced narrowing of central airway s combine synergistically to

produce extreme hyperresponsiveness in mice.” C.G. Irvin, L.M. Rinaldi, and J.H.T. Bates. Presented

at the American Thoracic Society Meeting, San Diego, May 20-25, 2005. Abstract in the Proceedings


F-235) “The forced oscillation technique: effects of smoking and COPD on lung physiology.” L.K.A.

Lundblad, S. Hansson, T. Jeppsson, U. Nihlen, C.G. Lofdahl, C.G. Irvin, J.H.T. Bates, and P.

Wollmer. Presented at the European Respiratory Society Annual Congress, Copenhagen, September

17-21, 2005. Abstract in the European Respiratory Journal. 26, Suppl. 49: 260s, 2005.

F-236) “Effects of heterogeneities and airway recruitment on global lung mechanics.” J.H.T. Bates and G.B.

Allen. Annual Fall Meeting of the Biomedical Engineering Society, Baltimore, September 28 -

October 1, 2005. Proceedings talk no. 533.

F-237) “Percolation of parenchymal lung disease and its effects on changes in mechanical function.” J.H.T.

Bates, G.S. Davis, A. Majumdar, and B. Suki. Annual Fall Meeting of the Biomedical Engineering

Society, Baltimore, September 28 - October 1, 2005. Proceedings talk no. 936.

F-238) “Changes in parenchymal density distribution on lung CT following methacholine: an indicator of

heterogeneous airtrapping.” D.A. Kaminsky, L. Lundblad, J. Thompson-Figueroa, J.S. Klein, M.

Sullivan, F. Flynn, S. Lang, L. Bourassa, S. Burns, C.G. Irvin, and J.H.T. Bates. Presented at the

American Thoracic Society Meeting, San Diego, May 19-24, 2006. Abstract in the Proceedings


F-239) “Unrestrained video-assisted plethysmography: a non-invasive method for measuring airway

47

resistance.” J.H.T. Bates, J. Thompson-Figueroa, and L.K.A. Lundblad. Presented at the American

Thoracic Society Meeting, San Diego, May 19-24, 2006. Abstract in the Proceedings American

Thoracic Society. Volume 3, Abstract Issue: A456, 2006.

F-240) “PAI-1 levels in bronchoalveolar fluid temporally correlate with a blunted response to recruitment and

PEEP.” G.B. Allen, T. Leclair, M. Cloutier, and J.H.T. Bates. Presented at the American Thoracic



F-241) “Airway closure in allergic mice during bronchoconstriction visualized with microCT.” L.K.A.

Lundblad, J. Thompson-Figueroa, G.B. Allen, C.G. Irvin, and J.H.T. Bates. Presented at the American

Thoracic Society Meeting, San Diego, May 19-24, 2006. Abstract in the Proceedings American

Thoracic Society. Volume 3, Abstract Issue: A789, 2006.

F-242) “Airways hyperresponsiveness in a mouse model of aspiration injury.” T. Leclair, J.H.T. Bates, and

G.B. Allen. Presented at the American Thoracic Society Meeting, San Diego, May 19-24, 2006.

Abstract in the Proceedings American Thoracic Society. Volume 3, Abstract Issue: A823, 2006.

F-243) “Peripheral lung inflammation and enhanced narrowing of central airways combine synergistically to

produce extreme hyperresponsive mice.” C.G. Irvin, L.M. Rinaldi, and J.H.T. Bates. Presented at the

1st National IDeA Symposium of Biomedical Research Excellence. Washington, D.C., July 20-22,

2006. Abstract in the Conference Proceedings, pp. C322.

F-244) “Hyperresponsiveness in allergic mice: the role of airway closure.” L.K.A. Lundblad, J. Thompson

Figueroa, G. Allen, C.G, and J.H.T. Bates. Presented at the 1st National IDeA Symposium of

Biomedical Research Excellence. Washington, D.C., July 20-22, 2006. Abstract in the Conference

Proceedings, pp. C323.

F-245) “Assessment of lung mechanics in mouse models of airways hyperresponsiveness.” J.H.T. Bates.

Presented at the 5th World Congress of Biomechanics, Munich, Germany, July 29 – August 4, 2006.

Abstract in the Journal of Biomechanics, Volume 39, Supplement 1: S269, 2006.

F-246) “Fuzzy logic for medical decision making.” J.H.T. Bates. Presented at the 17th Annual Meeting of the

European Society for Computing and Technology in Anesthesia and Intensive Care. Milan, Italy,

September 20-22, 2006.

F-247) “Mouse lung airway structure quantified by micro-CT.” J.H.T. Bates, J. Thompson-Figueroa, M.

Kavouksorian and L. Lundblad. Presented at the Annual Fall Meeting of the Biomedical Engineering

Society, Chicago, October 11-14, 2006. Proceedings no. 609.

F-248) “Development of a non-invasive method for measuring lung function in mice.” J.H.T. Bates, L.K.A.

Lundblad, J. Thompson-Figueroa and C.G. Irvin. Presented at the Annual Fall Meeting of the

Biomedical Engineering Society, Chicago, October 11-14, 2006. Proceedings no. 721.

F-249) “Spring recruitment model of lung tissue rheology.” J.H.T. Bates. Presented at the Annual Fall

Meeting of the Biomedical Engineering Society, Chicago, Octoberr 11-14, 2006. Proceedings no.

1374.

F-250) “Airways hyperresponsiveness in a mouse model of aspiration injury due to bronchial epithelial barrier

dysfunction.” T.R. Leclair, A.Cojocaru, J.H.T. Bates and G.B. Allen. Presented at the Annual Meeting

of the American Thoracic Society, San Francisco, May 18-23, 2007. Abstract in the American Journal

of Respiratory and Critical Care Medicine. Abstract Issue 175, pp. A155, 2007.

F-251) “Synergistic mechanisms of airways byperresponsiveness; dependence on mouse strain.” A.Cojocaru,

H. Haverkamp, C.G. Irvin and J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, San Francisco, May 18-23, 2007. Abstract in the American Journal of Respiratory

48

and Critical Care Medicine. Abstract Issue 175, pp. A156, 2007.

F-252) “Evolution of airways hyperresponsiveness and its physiologic basis after chronic allergic airways

disease.” H.C. Haverkamp, J.H.T. Bates and C.G. Irvin. Presented at the Annual Meeting of the


Respiratory and Critical Care Medicine. Abstract Issue 175, pp. A158, 2007.

F-253) “TGF- modulation of airway hyperresponsiveness; dependence on isotype.” L.K.A. Lundblad, R.

Norton, J.H.T. Bates and C.G. Irvin. Presented at the Annual Meeting of the American Thoracic

Society, San Francisco, May 18-23, 2007. Abstract in the American Journal of Respiratory and

Critical Care Medicine. Abstract Issue 175, pp. A350, 2007.

F-254) “Oxygen induces airways closure in inflamed airways.” K. Bhadra, J. Thompson-Figueroa, R. Norton,

C.G. Irvin, J.H.T. Bates and L.K.A. Lundblad. Presented at the Annual Meeting of the American



F-255) “Determinants of respiratory system impedance (Zrs) other than lung resistance (R) in subjects with

mild asthma.” D.A. Kaminsky, L. Lundblad, J. Thompson-Figueroa, S. Lang, L. Bourassa, S. Burns,

C.G. Irvin and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, San

Francisco, May 18-23, 2007. Abstract in the American Journal of Respiratory and Critical Care

Medicine. Abstract Issue 175, pp. A352, 2007.

F-256) “Relative compliance of airways and parenchyma in mice.” J. Thompson-Figueroa, M. Kavouksorian,

L.K.A. Lundblad, C.G. Irvin and J.H.T. Bates. Presented at the Annual Meeting of the American



F-257) “Informed consent practice in the intensive care unit (ICU).” E. Riesenfeld, K. Patel, J.H.T. Bates and

M. Young. Presented at the Annual Meeting of the American Thoracic Society, San Francisco, May

18-23, 2007. Abstract in the American Journal of Respiratory and Critical Care Medicine. Abstract

Issue 175, pp. A796, 2007.

F-258) “Late acute lung injury in mice is more unstable following deep inflation compared to early injury.”

G.B. Allen, J. Thompson-Figueroa, T. Leclair and J.H.T. Bates. Presented at the Annual Meeting of

the American Thoracic Society, San Francisco, May 18-23, 2007. Abstract in the American Journal of

Respiratory and Critical Care Medicine. Abstract Issue 175, pp. A943, 2007.

F-259) “A model of airway recruitment and derecruitment in the injured lung.” C.B. Massa and J.H.T. Bates.

Presented at the Annual Fall Meeting of the Biomedical Engineering Society, Los Angeles, September

26-29, 2007. Proceedings no. P1.155.

F-260) “Bronchoconstriction dynamics reflects airway wall stiffness in mice.” J.H.T. Bates, A. Cojocaru, H.

Haverkamp, and C.G. Irvin. Presented at the Annual Fall Meeting of the Biomedical Engineering

Society, Los Angeles, September 26-29, 2007. Proceedings no. P1.157.

F-261) “Emergent behavior in lung mechanics – what is it, and how can it arise?” J.H.T. Bates. Presented at

the Annual Fall Meeting of the Biomedical Engineering Society, Los Angeles, September 26-29,

2007. Proceedings no. 348.

F-262) “Modeling the dynamics of recruitment and derecruitment in the injured lung.” J.H.T. Bates, C.B.

Massa, and G.B. Allen. Presented at the Annual Fall Meeting of the Biomedical Engineering Society,

Los Angeles, September 26-29, 2007. Proceedings no. 708.

F-263) “In silico modeling of interstitial lung mechanics and repair.” B. Suki, A. Majumdar, J.H.T. Bates.

Presented at the Annual Fall Meeting of the Biomedical Engineering Society, Los Angeles, September

49

26-29, 2007. Proceedings no. P4. 139.

F-264) “Airways hyperresponsiveness in mice following acid aspiration is neutrophil dependent. G.B. Allen,

M.E. Cloutier, Y.C. Larrabee, B.T. Suratt, and J.H.T. Bates. Presented at the Annual Meeting of the


Respiratory and Critical Care Medicine. Abstract issue 177, pp. A62, 2008.

F-265) “Modeling the effects of airway smooth muscle shortening rate on the heterogeneity of

bronchoconstriction. R.C. Anafi and J.H.T. Bates. Presented at the Annual Meeting of the American


Critical Care Medicine. Abstract issue 177, pp. A513, 2008.

F-266) Neither fibrin nor PAI-1 deficiency confers protection of lung mechanical function in a mouse model

of acute lung injury.” G.B. Allen, M.E. Cloutier, Y.C. Larrabee, S.T. Smiley, and J.H.T. Bates.

Presented at the Annual Meeting of the American Thoracic Society, Toronto, May 16-21, 2008.

Abstract in the American Journal of Respiratory and Critical Care Medicine. Abstract issue 177, pp.

A599, 2008.

F-267) “Modeling the dynamics of airway contraction to methacholine in a mouse lung explant.” J.H.T. Bates,

A.M. Lauzon, Y. Bai, R.C. Anafi, and M.J. Sanderson. Presented at the Annual Meeting of the


Respiratory and Critical Care Medicine. Abstract issue 177, pp. A943, 2008.

F-268) “Airway remodeling: effects of Fluticasone and/or Salmeterol in a mouse model of asthma.” E.P.

Riesenfeld, L.M. Rinaldi, M.A. Sullivan, J.A. Thompson-Figueroa, H.VC. Haverkamp, J.M. Kelly,

J.H.T. Bates, and C.G. Irvin. Presented at the Annual Meeting of the American Thoracic Society,


Medicine. Abstract issue 177, pp. A944, 2008.

F-269) “Impedance measurements reveal peripheral process in asthma exacerbation.” L.K.A. Lundblad, S.

Lang, C. Fugere, L. Cicora, D.A. Kaminsky, R. Olivenstein, A.E. Dixon, J.G. Martin, J.H.T. Bates, Q.

Hamid, and C.G. Irvin. Presented at the Annual Meeting of the American Thoracic Society, Toronto,

May 16-21, 2008. Abstract in the American Journal of Respiratory and Critical Care Medicine.

Abstract issue 177, pp. A948, 2008.

F-270) “Airway closure and its relation to neutrophilic and eosinophilic inflammation in acute exacerbation of

asthma.” D.A. Kaminsky, L.K.A. Lundblad, A.E. Dixon, R. Olivenstein, S.E. Lang, D.M. Raymond,

J.H.T. Bates, Q. Hamid, J.G. Martin, and C.G. Irvin. Presented at the 51st Aspen Lung Conference,

Aspen CO, June 7, 2008. Abstract in Proceedings of the American Thoracic Society. 6: 335, 2009.

F-271) “Chronic inflammatory lung disease as a network malfunction.” J.H.T. Bates, and R. Anafi. Presented

at the Annual Meeting of the Biomedical Engineering Society, St. Louis, MO, Oct 1-4, 2008.

F-272) “Bifurcation behavior in a network model of co-existent pulmonary emphysema and fibrosis”. B. Suki,

A. Majumdar, V. Cottin, J.-F. Cordier, G. Davis, and J.H.T. Bates. Presented at the Annual Meeting

of the Biomedical Engineering Society, St. Louis, MO, Oct 1-4, 2008.

F-273) “Parallel versus serial compartmentalization in the constricted mouse lung.” B.L. Schwartz, and J.H.T.

Bates. Presented at the Annual Meeting of the Biomedical Engineering Society, St. Louis, MO, Oct 1-

4, 2008.

F-274) “Modeling the Response of Airway Smooth Muscle to Cyclic Loading.” S.R. Bullimore, A.-M.

Lauzon, A.Z. Politi, R.C. Anafi, J. Sneyd, and J.H.T. Bates. Presented at the Annual Meeting of the

Biophysical Society, Feb. 28 - Mar 4, 2009, Boston, MA. Abstract in the Biophysical Journal. 96

(Suppl. 1): 619a, 2009.

50

F-275) “Combined Acid Aspiration and Endotoxin Synergistically Recruit Airway Neutrophils and Disrupt

Barrier Function and Lung Mechanics.” G.B. Allen, K. Tetenev, J.A. von Reyn, M.E. Cloutier, and

J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, San Diego, May 17-


2009.

F-276) “Constant Infusion of Bronchial Agonists in Mice Does Not Always Produce a Constant Mechanical

Response.” J.H.T. Bates, A. Cojocaru, M. Aliyeva, and L.K.A. Lundblad. Presented at the Annual

Meeting of the American Thoracic Society, San Diego, May 17-20, 2009. Abstract in the American


F-277) “Effect of Deep Inspirations on Airway Smooth Muscle Force.” S.R. Bullimore, A.-M. Lauzon, A.Z.

Politi, R.C. Anafi, J. Sneyd, and J.H.T. Bates. Presented at the Annual Meeting of the American 48

Thoracic Society, San Diego, May 17-20, 2009. Abstract in the American Journal of Respiratory and

Critical Care Medicine. 179: A2069, 2009.

F-278) “Posture-Dependent Calculations of Airway Impedance and Its Relation to the Distribution of Patchy

Ventilation.” W. Chiu, ME, J.H.T. Bates, and M. Tawhai. Presented at the Annual Meeting of the

American Thoracic Society, San Diego, May 17-20, 2009. Abstract in the American Journal of


F-279) “Regional Mechanics in Acute Lung Injury: A Comparison of Function and Structure.” D.W. Kaczka,

K. Cao, G.E. Christensen, J.H.T. Bates, and B.A. Simon. Presented at the Annual Meeting of the

American Thoracic Society, San Diego, May 17-20, 2009. Abstract in the American Journal of


F-280) “The Effect of Acute and Protracted Inflammation on Airway Hyperresponsiveness.” L.K. Lundblad,

M. Poynter, M. Wu, S. Aimi, E. Riesenfeld, C. Irvin, and J.H.T. Bates. Presented at the Annual



F-281) “A Model of Cross-Linked Filaments Accounts for the Passive Properties of Airway Smooth Muscle.”

A.Z. Politi, S.R. Bullimore, A.M. Lauzon, J.H.T. Bates, and J. Sneyd. Presented at the Annual



F-282) “Airways Hyperresponsiveness and Major Basic Protein-1 or -2 Deficiency in a Murine Allergic

Airways Disease Model.” E.P. Riesenfeld, L.K.A. Lundblad, K. O'Neil, C. Protheroe, M. Wu, J.H.T.

Bates, J.J. Lee, N.A. Lee, and C.G. Irvin. Presented at the Annual Meeting of the American Thoracic

Society, San Diego, May 17-20, 2009. Abstract in the American Journal of Respiratory and Critical

Care Medicine. 179: A2441, 2009.

F-283) “A Network Model of Combined Pulmonary Emphysema and Fibrosis: Effects of Gravity.” B. Suki,

A. Majumdar, H. Parameswaran, V. Cottin, J.F. Cordier, G. Davis, J.H.T. Bates. Presented at the

Annual Meeting of the American Thoracic Society, San Diego, May 17-20, 2009. Abstract in the


F-284) “Physiological assessment and computational modeling of central airway obstruction caused by lung

cancer” J.H.T. Bates, L.K.A. Lundblad, D. Hitt, N. Vachon, and G. Davis. Presented at the Annual

Meeting of the European Respiratory Society, Vienna, Austria, September 12-16, 2009. Abstract in

the European Respiratory Journal. 34, Suppl. 53, P2700, 2009.

F-285) “Predicting the optimal rate for delivery of recruitment maneuvers in acute lung injury.”

J.H.T. Bates, and, G.B. Allen. Presented at the Annual Meeting of the European Respiratory Society,

Vienna, Austria, September 12-16, 2009. Abstract in the European Respiratory Journal. 34, Suppl. 53,

51

P3625, 2009.

F-286) “Comparison of lung impedances measured during spontaneous and tracked breathing.” N. Daphtary,

D.A. Kaminsky, and J.H.T. Bates. Presented at the Annual Meeting of the Biomedical Engineering

Society, Pittsburg, October 7-10, 2009.

F-287) “Airway hyperresponsiveness and the pathway to the smooth muscle.” J.H.T. Bates. Presented at the

Annual Meeting of the Biomedical Engineering Society, Pittsburg, October 7-10, 2009.

F-288) “Impact of increased shortening velocity on the response to dynamic loading in rat tracheal smooth

muscle strips.” S.R. Bullimore, A. Elvin, J. Sneyd, J.H.T. Bates, M.J. Sanderson, and A.-M. Lauzon.



F-289) “The development of ventilator-induced lung injury as a positive feed back consequence of deranged

surfactant function.” K.A. Grant, A.S. Seah, M. Aliyeva, G.B. Allen, and J.H.T. Bates. Presented at

the Annual Meeting of the American Thoracic Society, New Orleans, May 16-19, 2010. Abstract in

the American Journal of Respiratory and Critical Care Medicine. 181: A2722, 2010.

F-290) “TIMP-2 null mice have lower pulmonary impedance compared to weight-matched controls at

baseline and following lung injury.” J. Candon, D. Jaworski, J.A. von Reyn, M.E. Cloutier, J.H.T.

Bates, D.J. Weiss, and G.B. Allen. Presented at the Annual Meeting of the American Thoracic

Society, New Orleans, May 16-19, 2010. Abstract in the American Journal of Respiratory and Critical

Care Medicine. 181: A2723, 2010.

F-291) ”Acid aspiration injury amplified in vitro endotoxin signaling in cultured macrophages.” J.A. von

Reyn, M.E. Cloutier, J.H.T. Bates, and G.B. Allen. Presented at the Annual Meeting of the American

Thoracic Society, New Orleans, May 16-19, 2010. Abstract in the American Journal of Respiratory


F-292) “Noninvasive assessment of lung function in mouse models of obesity and pseudomonas infection

using unrestrained video-assisted plethysmography.” K.A. Accomando, J.A. Thompson-Figueroa,

B.T. Suratt, L. Bodden, M. Wargo, L.A. Whittaker, J.L. Allard, and J.H.T. Bates. Presented at the

Annual Meeting of the American Thoracic Society, New Orleans, May 16-19, 2010. Abstract in the


F-293) “Posture dependence of impedance in asthmatics suggests stiffer airways compared to controls.”

L.K.A. Lundblad, L. Griffes, M.J. Sullivan, S. Lang, J.H.T. Bates, and C.G. Irvin. Presented at the

Annual Meeting of the American Thoracic Society, New Orleans, May 16-19, 2010. Abstract in the


F-294) “Varying the duration of aerosol delivery: a means to probe the kinetics of methacholine transport to

the airway smooth muscle.” C.A. Stevenson, M. Aliyeva, L.K.A. Lundblad, S.H. Aimi, M. Wu, and

J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, New Orleans, May

16-19, 2010. Abstract in the American Journal of Respiratory and Critical Care Medicine. 181:

A2191, 2010.

F-295) “The relative roles of volutrauma and atelectrauma in a mouse model of ventilator-induced lung

injury.” A.S. Seah, K.A. Grant, G.B. Allen, M. Aliyeva, and J.H.T. Bates. Presented at the Annual

Meeting of the American Thoracic Society, New Orleans, May 16-19, 2010. Abstract in the American


F-296) "Dissociation between electrogram frequency and tissue frequency?” N. Habel, P. Znojkiewicz, N.

Thompson, A. Karnbach, B.E. Sobel, J.HT. Bates, and P.S. Spector. Presented at the Heart Rhythm

Society Meeting, 2010. Abstract in Heart Rhythm. 7: S350, 2010.

F-297) “Broken and unfixable – the recipe for an interesting existence.” Jason H.T. Bates. Presented at the

52

Montebello Round Table Discussion: Complexity and variability at the Bedside.” Le Chateau

Montebello, Quebec, Canada, September 28 – October 1, 2010.

F-298) “Multi-scale manifestations of airway smooth muscle mechanics.” J.H.T. Bates. Presented at the

Annual Meeting of the Biomedical Engineering Society, Austin, Texas, October 7-9, 2010.

F-299) “Long-range elastic interactions due to gravity in a network of co-existent pulmonary emphysema and

fibrosis.” B. Suki, H. Parameswaran, A. Majumdar, V. Cottin, J-F. Cordier, and J.H.T. Bates.

Presented at the Annual Meeting of the Biomedical Engineering Society, Austin, Texas, October 7-9,

2010.

F-300) “Simulation of dynamic recruitment-derecruitment in mouse lung under deep inflation.” B. Ma and

J.H.T. Bates. Presented at the Annual Meeting of the Biomedical Engineering Society, Austin,

Texas, October 7-9, 2010.

F-301) “A fuzzy logic algorithm for rationalized departure from 6 ml/kg tidal volume when ventilating the

injured lung.” J.H.T. Bates, H. Guler, B. Ma, and G.B. Allen. Presented at the Annual Meeting of

the American Thoracic Society, Denver, May 13-18, 2011. Abstract in the American Journal of


F-302) “The role of recruitment and derecruitment dynamics in the efficacy of variable tidal volume

ventilation.” B. Ma, B. Suki, J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, Denver, May 13-18, 2011.Abstract in the American Journal of Respiratory and


F-303) “Combined lipopolysacharride and acid-induced acute lung injury is attenuated by Gr-1 antibody

depletion of neutrophils.” T. Leclair, J. von Reyn, J.H.T. Bates and G.B. Allen. Presented at the

Annual Meeting of the American Thoracic Society, Denver, May 13-18, 2011.Abstract in the


F-304) “Is respiratory elastance and effort independent polyvalent lung function output?” L.K.A. Lundblad,

L. Griffes, D. Kaminsky, M.J. Sullivan, J.H.T. Bates, A.E. Dixon and C.G. Irvin. Presented at the

Annual Meeting of the American Thoracic Society, Denver, May 13-18, 2011.Abstract in the


F-305) “Orthogonal close unipolar recording: improved spatial resolution without direction dependence?” N.

Thompson, J. Stinnett-Donnelly, N. Habel, J.H.T. Bates, and P.S. Spector. Presented at the Heart

Rhythm Society Meeting, 2011. Abstract in Heart Rhythm. 8: S350, 2011.

F-306) “Modeling the dynamics of active airway narrowing.” J.H.T. Bates. Presented at the IEEE Engineering

in Medicine and Biology Meeting, Boston, Aug 30 – Sept 1, 2011. Abstract no. SaA12.1.

F-307) “Modeling the effects of airway contraction on parenchymal mechanics.” B. Ma, and J.H.T. Bates.

Presented at the Annual Meeting of the Biomedical Engineering Society, Hartford, CT, Oct 12-15,

2011. Abstract: Thurs-2-14-F.

F-308) “The Role of TLR-4 in ventilator-induced lung injury.” G.B. Allen, T. Tetenev, J. von Reyn, and

J.H.T. Bates. Presented at the Annual Meeting of the Biomedical Engineering Society, Hartford, CT,

Oct 12-15, 2011. Abstract: Fri-I-14-D.

F-309) “Assessing the stiffness of fibrotic airways.” J.H.T. Bates, J. van der Velden, and Y. Janssen-

Heininger. Presented at the Annual Meeting of the Biomedical Engineering Society, Hartford, CT, Oct

12-15, 2011. Abstract: PS-Fri-B-175.

F-210) “Effects of methacholine diffusivity across the airway wall on airways responsiveness” J.H.T. Bates,

C.A. Stevenson, M. Aliyeva, and L.K.A. Lundblad. Presented at the Annual Meeting of the

Biomedical Engineering Society, Hartford, CT, Oct 12-15, 2011. Abstract: PS-Fri-B-176.

53

F-311) “Temporal evolution of the phenotype of allergic airways hyperresponsiveness and airway

inflammation.” L.K.A. Lundblad, J.H.T. Bates, Riesenfeld, and M.E. Poynter. Presented at the Annual

Meeting of the Biomedical Engineering Society, Hartford, CT, Oct 12-15, 2011. Abstract: PS-Fri-B-

185.

F-312) “An agent-based model of the lung during an allergic asthmatic attack.” E. Martinez-Nieves, J. Pothen

and J.H.T. Bates. Presented at the 2011 Annual Biomedical Research Conference for Minority

Students, Nov 10, 2011.

F-313) “Computation model of lung injury progression due to mechanical overventilation.” B.J. Smith, D.P.

Gaver, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, San


Medicine, 185: A1046, 2012.

F-314) “Fuzzy logic tool for choosing tidal volume and PEEP in acute lung injury.” B. Nguyen, D.B.

Bernstein and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, San


Medicine, 185: A1683, 2012.

F-315) “Towards a complete description of human airway smooth muscle.” K. Murphy, J. Sneyd, M. Tawhai,

J.H.T. Bates, A.-M. Lauzon, and G. Donovan. Presented at the Annual Meeting of the American


and Critical Care Medicine, 185: A2083, 2012.

F-316) “A murine model of overventilation-induced lung injury at a peak end expiratory pressure of zero.”

B.J. Smith, K.A. Grant, and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic

Society, San Francisco, May 18-23, 2012. Abstract in the American Journal of Respiratory and

Critical Care Medicine, 185: A2123, 2012.

F-317) “Bronchoconstriction in mice allergic to house dust mite; a role for mast cells?” L.K.A. Lundblad, S.

Li, M. Aliyeva, N. Daphtary, J.L.I. van der Velden, S.M. Hoffman, K.G. Lahue, Y.M.W. Janssen-

Heininger, M.E. Poynter, J.H.T. Bates, C. Stevenson, and J. Phillips. Presented at the Annual Meeting

of the American Thoracic Society, San Francisco, May 18-23, 2012. Abstract in the American Journal

of Respiratory and Critical Care Medicine, 185: A2405, 2012.

F-318) “An agent-based model of allergic airway inflammation.” J. Pothen and J.H.T. Bates. Presented at the

Annual Meeting of the American Thoracic Society, San Francisco, May 18-23, 2012. Abstract in the

American Journal of Respiratory and Critical Care Medicine, 185: A2428, 2012.

F-319) “Dynamic airway contraction in a lung explants modeled by a spring network model and continuum

theory.” B. Ma, M. Sanderson, and J.H.T. Bates. Presented at the Annual Meeting of the American


and Critical Care Medicine, 185: A2698, 2012.

F-320) “Influence of parenchymal heterogeneity on airway-parenchymal interdependence.” B. Ma, and J.H.T.

Bates. Presented at the Annual Meeting of the American Thoracic Society, San Francisco, May 18-23,

2012. Abstract in the American Journal of Respiratory and Critical Care Medicine, 185: A2699, 2012.

F-321) “Differential effects of bariatric surgery on lung function in asthmatics and controls.” A. Al-Alwan,

D.A. Kaminsky, J.H.T. Bates, C.G. Irvin, and A.E. Dixon. Presented at the Annual Meeting of the


Respiratory and Critical Care Medicine, 185: A3953, 2012.

F-323) “Modeling and managing airway closure: implications for acute lung injury and asthma.” J.H.T. Bates.

The 40th Hakone Symposium on Respiration. Shiga, Japan, June 8-9, 2012. (Invited presentation)

54

F-324) “The inflammatory twitch: an agent-based model of allergic airway inflammation.” J. Pothen, and

J.H.T. Bates. Presented at the Annual Meeting of the Biomedical Engineering Society, Atlanta,

October 24-27, 2012. Abstract: P-Th-B-11.

F-325) “Modeling soft tissue stress relaxation as a random sequence of micro-yield events.” J.H.T. Bates.

Presented at the Annual Meeting of the Biomedical Engineering Society, Atlanta, October 24-27,

2012. Abstract: P-Sat-A-262.

F-326) “Progressive recruitment and derecruitment reflects the development of ventilator induced lung

injury.” B.J. Smith, G.B. Allen, and J.H.T. Bates. Presented at the Annual Meeting of the Biomedical

Engineering Society, Atlanta, October 24-27, 2012. Abstract: OP-Sat-3-12.

F-327) “The relationship between nonlinear lung elastance and ventilator-induced lung injury.” B.J. Smith,

and J.H.T. Bates. Presented at the Annual Meeting of the American Thoracic Society, Philadelphia,

May 17-22, 2013. Abstract in the American Journal of Respiratory and Critical Care Medicine. 187:

A1234, 2013.

F-328) “Modeling how the parenchyma mediates interactions between contracting airways.” B. Ma and J.H.T.

Bates. Presented at the Annual Meeting of the American Thoracic Society, Philadelphia, May 17-22,


F-328) “Experimental predictions of the inflammatory twitch using an agent-based model of allergic airway

inflammation.” J. Pothen, and J.H.T. Bates. Presented at the Annual Meeting of the American

Thoracic Society, Philadelphia, May 17-22, 2013. Abstract in the American Journal of Respiratory and


F-329) “A computational agent-based model of stem cell engraftment and proliferation patterns.” J. Pothen

and J.H.T. Bates. Presented at the Stem Cells and Cell Therapies in Lung Biology and Lung Disease

Conference, Burlington, Vermont, July 29 - August 1, 2013.

F-330) “Dynamic pressure-volume loops as predictors of long-timescale derecruitment in the lung.” B.J.

Smith and J.H.T. Bates. Presented at Annual Meeting of the European Respiratory Society, Barcelona,

Spain, September 7-11, 2013.

F-331) “Does the parenchyma mediate the ability of one airway to modulate the contraction of another?” B.

Ma and J.H.T. Bates. Presented at Annual Meeting of the European Respiratory Society, Barcelona,

Spain, September 7-11, 2013.

F-332) “Modeling the dynamics of recruitment and over-distension in the injured lung.” J.H.T. Bates and

B.J. Smith. Presented at the Annual Meeting of the Biomedical Engineering Society, Seattle, S

September 25-28, 2013.

F-333) “Computational analysis of dynamic pressure-volume observations to assess lung injury status.” B.J.

Smith and J.H.T. Bates. Presented at the Annual Meeting of the Biomedical Engineering Society,

Seattle, September 25-28, 2013.

F-334) “Bulk modulus and distribution of mechanical forces in a model of pulmonary fibrosis.” B.Suki,

C.L.N. de Oliveira and J.H.T. Bates. Presented at the Annual Meeting of the Biomedical Engineering

Society, Seattle, September 25-28, 2013.

F-335) ” A computational model of inter-airway interactions mediated by the parenchyma.” B. Ma and J.H.T.

Bates. Presented at the Annual Meeting of the Biomedical Engineering Society, Seattle, September 25-

28, 2013.

F-336) “An Agent-Based Model of Mesenchymal Stem Cell Dynamics of Lung Scaffolds.” J.J. Pothen, D.E.

Wagner , D. Weiss and J.H.T. Bates. Presented at the Annual Meeting of the Biomedical Engineering


55

F-337) “Identifying dynamic entrapment in a high-dimensional complex nonlinear system via coarse-grain

graph reduction: implications for cardiac arrhythmia.” O.R.J. Bates, J.H.T. Bates, B. Suki and P.S.

Spector. Presented at the Annual Meeting of the Biomedical Engineering Society, Seattle, September

25-28, 2013.

F-338) “Deconvolving electrograms of atrial fibrillation from intra-cardiac electrode arrays.” K.B. Palmer,

N.R. Thompson, P.S. Spector and J.H.T. Bates. Presented at the Annual Meeting of the Biomedical

Engineering Society, Seattle, September 25-28, 2013.

F-339) “Ablation of Multi-Wavelet Reentry Guided by Circuit Density.” R. Carrick, B. Benson, O. Bates, N.

Habel, J.H.T. Bates, and P. Spector Presented at the Annual Meeting of the Biomedical Engineering


F-340) “Termination of Multi-Wavelet Reentry is a Probabilistic Event.” Submitted for presentation at the

Heart Rhythm Society Conference, San Francisco, May 7-10, 2014.

F-341) “Fibrillation number: A Dimensionless metric for assessing the propensity to Fibrillate.” Submitted for

presentation at the Heart Rhythm Society Conference, San Francisco, May 7-10, 2014.

F-342) “Improved Accuracy of Multi wavelet reentry Mapping.” Submitted for presentation at the Heart

Rhythm Society Conference, San Francisco, May 7-10, 2014.

F-343) “Interactions between airway wall stiffness and lung volume: the emergence of a population at risk for

obese asthma.” J.H.T. Bates, and A.E. Dixon. Invited presentation at the 7th World Congress of

Biomechanics, Boston, July 6-11, 2014.

F-344) “Temporal Changes in Pulmonary Function and Computed Tomography Scans in Patients with

Pulmonary Fibrosis.” T.J. Wellman, G.S. Davis, J.H.T. Bates, and B. Suki. Invited presentation at the

7th World Congress of Biomechanics, Boston, July 6-11, 2014.

F-345) “A composite cost function for quantifying ventilator-induced lung injury.” J.H.T. Bates and B.J.

Smith. Submitted for presentation at the Annual Meeting of the Biomedical Engineering Society,

San Antonio, October 22-25, 2014.

F-346) “A computational model of epithelial cell monolayer disruption in the lung.” B. Ma and J.H.T.

Bates. Submitted for presentation at the Annual Meeting of the Biomedical Engineering Society,

San Antonio, October 22-25, 2014.

F-347) “Personalized predictions of recruitment, derecruitment, and tissue distention in the injured lung.”

B. Smith, L. Lundblad, J. Satalin, M. Kollisch-Singule, B. Emr, K. Snyder, L. Gatto, P. Andrews,

N. Habashi, G. Nieman, and J.H.T. Bates. Submitted for presentation at the Annual Meeting of the

Biomedical Engineering Society, San Antonio, October 22-25, 2014.

F-348) “Agent-based models for studying stem cell dynamics on decellularized lung scaffolds.” J. Pothen, V.

Rajendran, D. Wagner, D. Weiss, and J.H.T. Bates. Submitted for presentation at the Annual Meeting

of the Biomedical Engineering Society, San Antonio, October 22-25, 2014.

F-349) “An agent-based network model of pulmonary fibrosis development.” T. Wellman1, J.H.T. Bates, G.

Davis, and B. Suki. Submitted for presentation at the Annual Meeting of the Biomedical Engineering

Society, San Antonio, October 22-25, 2014.

56

G) Patents

G-1) “Mechanical Ventilator”. J.H.T. Bates, T.F. Schuessler and M. Ahmadi. U.S. Patent #6,082,357.

Priority data March 26, 1997.

G-2) “Breathing Biofeedback Method and System.” P. Bingham and J.H.T. Bates. US Patent # 7,618,378

B2, Nov 17, 2009.

G-3) “Noninvasive Pulmonary Airway Resistance Measurement System”. J.H.T. Bates, J. Thompson-

Figueroa, L.K.A. Lundblad and C.G. Irvin. US 7,945,303 B2, May 17, 2011.

G-4) “Variable ventilation as a diagnostic tool for assessing lung mechanical function.” J.H.T. Bates and

B.S. Smith. USPTO serial # 61/943,468, patent pending.

57

G) Invited Addresses

1) Beer Seminar, Meakins-Christie Laboratories, McGill University, Montreal, 14 Dec 1983, "Resolution

Enhancement of Respiratory Laboratory Instruments".

2) Biomedical Engineering Dept. of McGill University, Montreal, 24 Feb 1984, "Techniques of

Deconvolution".

3) The Medical Physics Dept. of the Montreal General Hospital, 11 April 1984, "Deconvolution".

4) Meakins-Christie Laboratories, McGill University, Montreal, 10 Oct 1984, "The Importance of

Viscoelastic Properties of the Respiratory System on Breathing".

5) Meakins-Christie Laboratories, McGill University, Montreal, 26 October, l984, "Methods of data

analysis and the applications using the IBM Personal Computer".

6) The Chest Hospital, Pellenburg, Belgium, 6 December 1984, "Mechanical inhomogeneities and the

importance of viscoelasticity in the lung".

7) Istituto di Medicina del Lavoro, University of Padova, Padova, Italy, 14 December l984, "The

importance of the viso-elastic properties of the respiratory system in breathing".

8) Department of Medicine, Royal Postgraduate Medical School, London, 2 January l985, "Mechanical

inhomogeneities in the respiratory system.

9) Section of Physiology, Department of Medicine, School of Medicine, University of California San

Diego, La Jolla, CA, 2 May l985, "The passive mechanical properties of the respiratory system and

their consequences for breathing".

10) McGill-Dartmouth Meeting, Meakins-Christie Laboratories, McGill University, Montreal, Quebec, 24

May l985, "Optimal breathing pattern".

11) Biomedical Engineering Unit, McGill University, Montreal, Quebec, 8 November l985, "Identification

and modeling of respiratory mechanics".

12) Clinical Physiology Department, Greenlane Hospital, Auckland, New Zealand, 3 December l985,

"The noninvasive assessment of respiratory mechanics".

13) McGill-Dartmouth meeting, Department of Physiology, Dartmouth College, Hanover, New

Hampshire, 23 May 1986, "Computer implementation of the interrupter method for measuring

respiratory resistance".

14) Meakins-Christie Laboratories, McGill University, Montreal ("Beer Seminar"), October 1986,

"Resistus-Interruptus: An effective method of breath control."

15) Dept. Biomedical Engineering, University of Southern California, Los Angeles, December 10, 1986.

"The interrupter method for measuring respiratory resistance."

16) Dept. Physiology, School of Medicine, Universityof California San Diego, La Jolla, December 12,

1986. "Resistus interruptus - an effective method of breath control?"

17) McGill-Dartmouth Meeting, McGill University, Montreal, June 5-6, 1987, "Chest wall resistance".

18) Padua University, Padua, Italy, July 20, 1987. "The interrupter method for measuring respiratory

resistance."

19) Academic Hospital St. Barbara, Pellenburg (Leuven), Belgium, July 23, 1987. "The inte/rrupter

method for measuring respiratory resistance."

58

20) Beer Seminar "Decomposition of muscle tension into individual twitches". Meakins-Christie

Laboratories, McGill University, October 7, 1987.

21) Symposium on Current Issues on Respiratory Research. "The Interrupter Technique." Boston

University, Nov. 13, 1987.

22) Beer seminar, Vancouver General Hospital, 3 Feb 1988. "Resistus Interruptus".

23) Physiology Department, Greenlane Hospital, Auckland, New Zealand, 11 Feb 1988. "Modelling the

mechanical behaviour of the respiratory system."

24) Christchurch School of Medicine, Christchurch, New Zealand, 7 March 1988. "Modelling the

mechanical behaviour of the respiratory system".

25) Symposium on viscoelastic behaviour of lung tissues, Meakins-Christie Laboratories, McGill

University, Montreal, 31 March 1988. "Modeling the respiratory system".

26) Meakins-Christie Laboratories, McGill University, September 14, 1988, Beer Seminar. "A model

fitting approach to estimating respiratory mechanics".

27) Biomedical Engineering Unit Seminar, McGill University, Montreal, April 5, 1989. "Modelling

respiratory mechanics".

28) Meakins-Christie Laboratories, McGill University, September 13, 1989, Beer Seminar. "Forced

oscillations through alveolar capsules".

29) Department of Physiology, McGill University, Montreal, 6 October 1989. "Studies of canine

respiratory mechanics".

30) Meakins-Christie Laboratories, McGill University, Montreal, 14 February 1990, Beer Seminar.

"Muscle spirals and other mechanical determinants of airway hyperresponsiveness." (with Dr. J.

Martin)

31) Dept. Anesthesia, The Hospital for Sick Children, "Model fitting in respiratory mechanics", and Dept.

Physiology, University of Toronto, "Modeling the low-frequency mechanical behavior of the

respiratory system", Toronto, January 14, 1990.

32) Workshop on respiratory mechanics at low frequencies, Department of Biomedical Engineering,

Boston University, Boston, MA, 25 May 1990. "Separating tissue and gas flow effects using gases of

different physical properties."

33) Electrical and Electronic Engineering Seminar, University of Canterbury, Christchurch, New Zealand,

12 July 1990. "Advances in understanding of pulmonary physiology and related biomedical

engineering implications."

34) Chest Disease Research Institute, Kyoto University, Kyoto, Japan, 12 July 1991. "Studies of the lung

using the alveolar capsule technique".

35) Chest Disease Research Institute, Kyoto University, Kyoto, Japan, 12 July 1991. "Instrumentation,

data acquisition, and computerized data analysis in the study of respiratory mechanics".

36) Department of Thoracic and Cardiovascular Surgery, Shizuoka City Hospital, Shizuoka, Japan, 17

July 1991. "A modeling approach to understanding respiratory mechanics".

37) Department of Geriatrics, Faculty of Medicine, University of Tokyo, Tokyo, Japan, 19 July 1991.

"Studies of the lung using the alveolar capsule technique".

38) Department of Respiratory Medicine, School of Medicine, Kitasato University, Kitasato, Japan, 23

July 1991. "Overview of respiratory mechanics".

59

39) Department of Respiratory Medicine, Princess Margaret Hospital, Perth, Australia, 25 July 1991.

"Temporal dynamics of bronchoconstriction".

40) Lung Research Group, Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Perth,

Australia, 26 July 1991. "Relative viscoelastic properties of airways and parenchyma".

41) Electrical and Electronic Engineering Seminar, University of Canterbury, Christchurch, New Zealand,

1 August 1991. "A non-statistical approach to estimating confidence intervals about model parameters

and its application to respiratory mechanics".

42) Beer Seminar, Meakins-Christie Laboratories, Sept 18, 1991. "A new way of fitting the ̀ Equation of

motion'".

43) Hammersmith Hospital, Dept. Paediatrics, Sept 30, 1991. "The interrupter method."

44) Meeting of the Respiratory Health Network of Centres of Excellence, Far Hills Inn, Quebec, 1992.

45) Department of Biomedical Engineering, Boston University, March 13, 1992. "Pulmonary mechanics

during bronchoconstriction."

46) Pulmonary Research Laboratory, St. Paul's Hospital, vancouver, BC, March 27, 1992. "Changes in

pulmonary mechanics during bronchoconstriction."

47) Dept. Physiology, School of Medicine, University of California San Diego, April 13, 1992. "Changes

in pulmonary mechanics during bronchoconstriction."

48) Beer Seminar, Meakins-Christie Labs, McGill University, Montreal, Quebec, April 28, 1992.

"Changes in pulmonary mechanics during bronchoconstriction."

49) Respiratory Mealth Network of Centres of Excellence Annual Meeting, Merck Frosst Canada,

Montreal, Quebec, June 18, 1992. "A portable patient system for respiratory mechanics."

50) "Changes in respiratory mechanics during bronchoconstriction". Biomedical Engineering Department,

McGill University, Montreal, October 2, 1992.

51) "The forest or the trees". Beer Seminar, Meakins-Christie Laboratories, McGill University, Montreal.

52) "Changes in pulmonary mechanics during bronchoconstriction." Division of Respiratory Medicine,

Children's Hospital of Philadelphia, Philadelphia, PA, November 3, 1992.

53) "Changes in pulmonary mechanics during bronchoconstriction." Instituto Fisiologia Umana I,

Universita di Milano, Nov 24, 1992.

54) "Changes in pulmonary airway and tissue impedances during bronchoconstriction." Department of

Paediatrics, Hammersmith Hospital, London, England, Nov 30, 1992.

55) "Lung inhomogeneities during bronchoconstriction." Scotch Seminar, Royal Victoria Hospital,

Montreal, February 12, 1993.

56) "Brochoconstriction and broken symmetry." Beer Seminar, Meakins-Christie Labs, McGill

University, Montreal, September 7, 1993.

57) "Lung tissue mechanics and 1/f noise." Department of Physiology, University of California, San

Diego, CA, May 2, 1994.

58) "Mechanical impedance of lung tissue." Instituto de Biofisica Carlos Chagas Filho, Universidade

Federal do Rio de Janeiro, Rio de Janeiro, Brazil, August 31, 1994.

59) "Inhomogeneities during bronchoconstriction". Flow-Volume Underworld Meeting, Comogli, Italy,

October 6-7, 1994.

60

60) "Time course of rat lung mechanics." Beer Seminar, Meakins-Christie Laboratories, McGill

University, Montreal, February 7, 1995.

61) "Measurement issues in animal models of asthma." Workshop on animal models of asthma,

Respiratory Health Network of Centres of Excellence and Merck Frosst Canada Ltd., La Sapiniere,

Quebec, March 1-3, 1995.

62) "Bronchial collapse." Mini symposium on surface tension and the lung, Meakins-Christie

Laboratories, McGill University, Montreal, Quebec, April 6, 1995.

63) "An entropy model of lung tissue mechanics." Beer Seminar, Meakins-Christie Laboratories, McGill

University, Montreal, October 3, 1995.

64) "Fuzzy logic." Research seminar, Western Australia Research Institute for Child Health, Perth,

Australia, November 29, 1995.

65) “An entropy model of lung tissue rheology.” Biomedical Engineering Department, McGill University,

Montreal, October 2, 1996.

66) “Neural networks and the lungs.” Beer Seminar, Meakins-Christie Laboratories, January 7, 1997.

67) “An entropy model of lung tissue rheology.” Department of Biomedical Engineering, Boston

University, Boston, April 4, 1997.

68) “The volume dependence of bronchial hyperresponsiveness.” Calgary Health Sciences Centre, May

15, 1997.

69) “The assessment of respiratory mechanics: a modeling perspective.” Astra-Draco, Lund, Sweden,

September 25, 1997.

70) “The volume dependence of bronchial responsiveness.” Institute of Child Health, London, England,

October 1, 1997.

71) “Respiratory mechanical changes during induced bronchoconstriction in animals.” Royal Victoria

Hosptal/McGill Department of Medicine Research Day, Holiday Inn Crowne Plaza, Montreal,

November 8, 1997.

72) “Mechanical properties of lung tissue.” Centre for Nonlinear Dynamics in Physiology and Medicine,

McGill University, Montreal, November 27, 1997.

73) “Mechanical determinants of bronchial responsiveness”. Department of Biomedical Engineering,

McGill University, Montreal, September 23, 1998.

74) “Volume dependence of bronchial responsiveness”. Beer Seminar, Meakins-Christie Laboratories,

McGill University, Montreal, November 3, 1998.

75) “Bronchial responsiveness in the rat.” Astra-Draco Inc., Lund, Sweden, May 31, 1999.

76) “Mechanical factors that influence bronchial responsiveness in animals.” Cleveland Clinic, Cleveland,

OH, August 23, 1999.

77) “Bronchoconstriction and airway-parenchymal interdependence.” Department of Biomedical

Engineering, Boston University, September 13, 1999.

78) “Modulating bronchial responsiveness in animals by changing lung volume." Department of

Molecular Physiology and Biophysics, The University of Vermont, Burlington, VT, September 20,

1999.

79) “The mechanics of lung tissue.” Department of Mechanical Engineering, The University of Vermont,

Burlington, VT, February 4, 2000.

61

80) “The dynamics of bronchoconstriction in animals.” Work-in-Progress Seminar, Physiology Program,

Harvard School of Public Health, March 14, 2000.

81) “The phenotyping uncertainty principle”. Meakins-Christie Workshop “Pathogenesis and Treatment of

Asthma and COPD”, Hotel Manoir des Sables, Magog-Orford, Quebec, Feb 4-5, 2001.

82) “Measuring outcomes: pulmonary physiology”. ATS Postgraduate Course PG-05 - Experimental

techniques for environmental and occupational lung diseases, San Francisco, May 18, 2001.

83) “Fuzzy logic for ventilator management.” ATS Meeting C04 - Math in the ICU, San Francisco, May

22, 2001.

84) “Does sighs matter” Implications for mechanical ventilation of the injured lung.” Department of

Biomedical Engineering, Boston University, Boston, MA 02215. Feb 14, 2002.

85) “The phenotyping uncertainty principle”. American Thoracic Society Postgraduate Course, Atlanta,

May 17, 2002.

86) “Linking mechanical function to structure in the mouse lung.” Vermont Lung Center, University of

Vermont, September 10, 2002.

87) “Linking mechanical function to structure in the mouse lung.” Department of Molecular Physiology

and Biophysics, University of Vermont, November 4, 2002.

88) “Linking mechanical function to structure in the mouse lung.” Beer Seminar, Meakins-Christie

Laboratories, McGill University, Montreal, Canada, November 5, 2002.

89) “Linking structure to function in mouse models of asthma.” 6th Annual Meakins-Christie MUHC

Research Institute Workshop, Saint-Sauveur, Quebec, Feb 16-17, 2003.

90) “Measurement of respiratory mechanics.” 15 min presentation in session on ARDS, 23rd

International

Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 18-21, 2003.

91) “What are the challenges?.” 15 min presentation in session on automation in ventilation, 23rd

International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 18-

21, 2003.

92) “Measuring respiratory mechanics.” 50 min tutorial, 23rd

International Symposium on Intensive Care

and Emergency Medicine, Brussels, Belgium, March 18-21, 2003.

39) “Respiratory mechanics.” 15 min presentation in session on bedside monitoring, 23rd

International

Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 18-21, 2003.

94) “Linking structure to function in the mouse lung.” Robarts Institute, London, Ontario, Canada, July

28, 2003.

95) “Allergic airways hyperresponsiveness – normal smooth muscle in an abnormal lung.” Flow-Volume

Underworld Meeting, Grand Isle, Vermont, Sept 12, 2003.

96) “Linking structure to function in a mouse model of allergic inflammation.” Dept. Radiology,

University of Iowa, Iowa City, Dec 18, 2003.

97) “Power laws in nature. Are they really there and if so, where do they come from?” Dept. Mechanical

Engineering, University of Vermont, Burlington, VT, Jan 23, 2004.

98) “Artificial neural networks, and engineering with tool with biological implications.” Cell Signaling

Group, College of Medicine, University of Vermont, Burlington, VT, Jan 26, 2004.

99) “Recruitment and derecruitment in the lung: A dynamic phenomenon.” 7th Annual Meakins-Christie

Workshop, Bromont, Quebec, Feb 1-2, 2004.

62

100) “Measuring lung function in mice.” Departement de Pharmacologie Generale, Sanofi-Synthelabo

Recherche, 10 rue des Carrieres, 92504 Rueil-Malmaison, France, March 29, 2004.

101) “Respiratory mechanics.” 45 min tutorial, 24rd

International Symposium on Intensive Care and

Emergency Medicine, Brussels, Belgium, March 30-April 2, 2004.

102) “Pulmonary mechanics in the ventilated patient.” 15 min presentation in session on the basics in

cardiorespiratory physiology, 24rd

International Symposium on Intensive Care and Emergency

Medicine, Brussels, Belgium, March 30-April 2, 2004.

103) “The physiology of recruitment maneuvers.” 15 min presentation in session on lung recruitment, 24rd

International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 30-

April 2, 2004.

104) “Automatic control of mechanical ventilation.” 15 min presentation in session on mechanical

ventilation, 24rd

International Symposium on Intensive Care and Emergency Medicine, Brussels,

Belgium, March 30-April 2, 2004.

105) “Indications and limitations of current methodologies for the assessment of mechanical changes due to

airway remodeling.” Presentation (1 hour) at the 22nd

Symposium of the Veterinary and Comparative

Respiratory Society, Old Montreal, Quebec, October 1-3, 2004.

106) “The force-velocity behavior of airway smooth muscle, and what it means for bronchial

responsiveness.” Beer Seminar, Meakins-Christie Laboratories, McGill University, Montreal, Nov. 30,

2004 .

107) “Modeling the dynamics of airway smooth muscle contraction.” Research Forum, Department of

Molecular Physiology and Biophysics, University of Vermont. Feb 4, 2005.

108) “Physical determinants of airway smooth muscle shortening in situ.” 8th Annual Meakins-Christie

Workshop, Magog-Orford, Quebec, Canada, Feb 6-7, 2005.

109) “Modeling the dynamics of bronchoconstriction. Smooth Muscle Workshop, Meakins-Christie

Laboratories, McGill University, Montreal, October 27, 2005.

110) “Synergy between the determinants of airways hyperresponsiveness: A theoretical analysis.” 9th

Annual Meakins-Christie Workshop, Ste-Adele, Quebec, Canada, Feb 11-13, 2005.

111) “Sequential micro-rips: a mechanism for stress adaptation in biological soft tissue.” Department of

Biomedical Engineering, Boston University, Boston, MA, May 3, 2006.

112) “Mechanical mechanisms of airway hyperresponsiveness in animals models.” Department of

Physiology, University of Massachusetts Medical School, Worcester, MA, May 4, 2006.

113) “Fuzzy logic for medical decision making.” 17th Annual Meeting of the European Society for

Computing and Technology in Anesthesia and Intensive Care. Milan, Italy, September 20-22, 2006.

114) “Airway-parenchymal interdependence, wall stiffness, and the dynamics of bronchoconstriction." 10th

Annual Meakins-Christie Workshop, St. Sauveur, Quebec, Canada, Feb 3-5, 2007.

115) “Airway wall stiffness and deep inflations in mice.” Beer Seminar, Meakins-Christie Laboratories,

McGill University, Montreal, Jun 4, 2007 .

116) “Measuring lung mechanical function in mice.” Pulmonary Symposia, Trudeau Institute, Inc., Jul 27,

2007.

117) “Phenotyping mouse models of asthma: linking structure to function.” Invited speaker and chair, ATS

symposium “Two decades of making mouse models of allergic asthma: where has it gotten us?”,

Toronto, May 20, 2008.

63

118) “Physiological phenotyping animal models.” Invited speaker, ATS symposium “Phenotypic

fingerprinting in asthma and COPD”, San Diego, May 20, 2009.

119) “Heterogeneity and impedance.” Flow-Volume Underworld Meeting, Baltimore, Sept 30 - Oct 2,

2009.

120) “Measuring and modeling lung mechanics.” Department of Biomedical Engineering, University of

Western Ontario, London, Ontario, Canada, October 13, 2009.

121) “The kinetics of airway smooth muscle contraction in situ. North East Smooth Muscle Meeting,

University of Vermont, Burlington, Vermont, October 23-24, 2009.

122) “Systems biology and the behavior of complex dynamics networks.” Grand Rounds, Department of

Medicine, Fletcher Allen Health Care, Burlington, VT, March 2010.

123) “Systems biology and the behavior of complex dynamics networks.” Department of Anesthesiology,

Fletcher Allen Health Care, Burlington, VT, August 5, 2010.

124) “Complex systems in medicine.” Ob/Gyn & reproductive Sciences Grand Rounds. Fletcher Allen

Health Care, Burlington, VT, November 23, 2010.

125) “Complex systems in biology and medicine.” Continuing Education, University of Vermont, April 28,

2011.

126) “The dynamics of recruitment and derecruitment in acute lung injury.” Meet the Professor seminar at

the American Thoracic Society meeting. Denver, CO, May 15, 2011.

127) “Grantsmanship.” Invited speaker at the American Thoracic Society symposium on Transitioning to a

Successful Academic Career. Denver, CO, May 15, 2011.

128) “Fuzzy logic ventilation.” Invited presentation at the 24th Annual Congress of the European Society of

Intensive Care Medicine. Berlin, Germany, 1-5 October, 2011.

129) “The science of complexity.” OSHER talk at the University of Vermont, October 27, 2011.

130) “A physicist’s life in the lungs: the good, the bad and the viscoelastic.” Christie Lecture, Meakins-

Christie Laboratories, McGill University, Montreal, November 21, 2011.

131) “Finding ventilatory strategies that minimize the progression of ventilator-induced lung injury.” Final

Meeting of the German Research Foundation (DFG) - Priority Program “Protective Artificial

Respiration”, Technical University of Municha, March 1-2, 2012.

132) “A unified view of the mechanical behavior of active and passive smooth muscle.” St. Paul’s Hospital,

University of British Columbia, Vancouver, BC, March 17, 2012.

133) “Airways Hyperresponsiveness in Mice: Mechanisms from Models.” St. Joseph’s Hospital, McMaster

University, Hamilton, Ontario, Canada, April 3, 2012.

134) “Dynamic complexity in lung tissue mechanics.” Department of Bioengineering, University of Illinois

at Chicago, Chicago, IL, April 13, 2012.

135) “Respiratory systems.” ECHO “Our Body” After Dark Speaker Series. Burlington, VT, April 19,

2012.

136) “The interaction of the airways and parenchyma during bronchoconstriction.” Scientific Symposium

“Airway remodeling and hyperresponsiveness in asthma: what are they and what can we do about

them?” Annual Meeting of the American thoracic Society, San Francisco, May 18-23, 2012.

137) “Mechanical determinants of airways hyperresponsiveness – lessons from mouse models.” The 7th

Kyoto International Conference (KIC). Kyoto University School of Medicine, Kyoto, Japan, June 11,

64

2012.

138) “Connective tissue and smooth muscle - perhaps more similar than we thought?” Flow-Volume

Underworld, Vancouver, BC, Canada, June 20-22, 2012.

139) “Mechanical determinants of airways hyperresponsiveness.” Carlos Chagas Filho Biophysics Institute,

Federal University of Rio de Janeiro, Brazil, August 31, 2012.

140) “Quantifying the roles of tidal volume and PEEP in the pathogenesis of ventilator-induced lung

injury.” Copa D’Or Hospital, Rio de Janeiro, Brazil, August 31, 2012.

141) “The roles of tidal volume and PEEP in the pathogenesis of ventilator-induced lung injury.”Invited

presentation, Annual Congress of the Brazilian Physiological Society, Gramado, Brazil, September 2-

5, 2012.

142) “Pathophysiology of airways hyperresponsiveness in mouse models of allergic airway disease.”Invited

presentation, Annual Congress of the Brazilian Physiological Society, Gramado, Brazil, September 2-

5, 2012.

143) “Complex disease as an aberrant network phenomenon.” Invited presentation, 11th International

Conference on Complexity in Acute Illness, Ottawa, September 6-9, 2012.

144) “Insults and consequences in the murine lung: what can we learn from lung mechanics?”

Environmental & Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ,

September 27, 2012.

145) “Predicting the influence of lung inflation pressure on the responsiveness of the airways to challenge

with a smooth muscle agonist.” (co-authored by B. Ma, A.-M. Lauzon, and M. J. Sanderson).

Interagency Modeling and Analysis Group meeting, NIH, Bethesda, Oct 23, 2012.

146) “Don’t be constantly fazed by the constant-phase model.” Vermont Lung Center Seminar, University

of Vermont, Nov 13, 2012.

147) “Representing the dynamic mechanical behavior of the lung with mathematical models.” Applied

Mathematics Seminar, University of Vermont, Mar 15, 2013.

148) “Interpretation of lung mechanics: from trivial to complex.” Lecture for the Postgraduate Course:

PG4 How to build an experimental animal lung lab, Annual Meeting of the European Respiratory

Society, Barcelona, Spain, September 7-11, 2013.

149) “The dynamic mechanical function of the lung as a signature of pulmonary disease.” Clarkson

University, April 8, 2014.

65

GRANTS

A) Salary Support for Jason H.T. Bates

1986-91 Medical Research Council Scholarship.

1991-94 Chercheur-boursier "Senior 1" of the Fonds de la Recherche en Sante du Quebec.

1994-97 Chercheur-boursier "Senior 2" of the Fonds de la Recherche en Sante du Quebec.

B) Salary support for personnel working under supervision of Jason H.T. Bates

1989-91 Research Institute of The Royal Victoria Hospital, Montreal, Graduate Fellowship awarded to

Anne-Marie Lauzon ($6,000 per annum).

1992-93 Research Institute of The Montreal Chest Hospital, Montreal, Graduate Fellowship awarded

to Anne-Marie Lauzon ($7,000 per annum).

1990-92 Canadian Lung Association Physiotherapy Graduate Fellowship awarded to Gail Dechman

($10,000 per annum).

1992-93 Medical Research Council Graduate Fellowship awarded to Gail Dechman ($15,000 per

annum).

1991-96 National Science and Engineering Research Council Graduate fellowship awarded to

Geoffrey Maksym ($15,000 per annum).


to Thomas Schuessler ($7,000 per annum).

1992 Medical Research Council of Canada, Eastern European Visiting Scientist Fellowship,

awarded to Oleg Reich ($25,000 for 6 months with travel award and $5000 research

allowance).

1992 Respiratory Health Network of Centres of Excellence, Post-Doctoral Fellowship awarded to

Oleg Reich ($15,000 for 6 months).

1994-95 McGill Major Fellowship awarded to Thomas Schuessler ($10,000).


to Mohsen Ahmadi ($7,000 per annum).

1996-98 Medical Research Council of Canada Graduate Student Fellowship awarded to Mohsen

Ahmadi ($15,000 per annum).


to Thomas Schuessler ($7,000 per annum).

1996-97 Research Institute of The Montreal Chest Hospital, Montreal, Post-doctoral Fellowship

awarded to Andrew Adler ($14,000 per annum).

1996-97 Natural Sciences and Engineering Research Council of Canada Post-Doctoral Fellowship

awarded to Andrew Adler ($29,000 per annum).


to Rute Gomes ($7,000 per annum).

66

2004-2009 K08 Award from the National Institutes of Health awarded to Gilman B. Allen, MD

($100,000 per annum).

2011-2015 K23 Award from the National Institutes of Health awarded to Renee Stapleton, MD, PhD

($100,000 per annum).

2011 – present NIH Training Grant Post-Doctoral Fellowship awarded to Bradford J. Smith.

2011 – present NIH Training Grant Pre-Doctoral Fellowship awarded to Joshua Pothen

C) Operating Grants

1986-87 "The Development and Application of Methodologies for the Investigation of Respiratory

Mechanics". (principal investigator) Canadian Medical Research Council Operating Grant

$30,004 over 2 years.



(renewal) $115,004 over three years.

1990-98 "Respiratory Health" Network of Centres of Excellence. I am part of the physiologic diagnosis

and digital morphometry subgroups of the network, headed by Dr. P.T. Macklem and centred

at the Meakins-Christie Laboratories. The centre is a multi-million dollar operation across

Canada for the integration of university research and industrial development. My research

funding from the NCE is about $35,000 per year.









(termination) $25,000.

1995-98 "The Quantitative Study of Lung Mechanics". Canadian Medical Research Council Operating

Grant, $183,000 over three years plus MRC Graduate Studentship (principal investigator).

Application rated #1 by the Biomedical Engineering Committee.

1997-98 “Structure-function study of the late response in guinea pigs”. (principal investigator) Astra-

Draco Inc., Lund, Sweden, $40,000 (operating grant approved by FRSQ).

1998-2001 "The Quantitative Study of Lung Mechanics". (principal investigator) Canadian Medical

Research Council Operating Grant renewal, $193,148 over three years.

2000 “Translational research in lung biology and disease.” A COBRE grant funded by the NIH (PI:

Charles, G. Irvin, PhD). Role: Co-Principal Investigator, Leader of Bioengineer Core, and

Mentoring Investigator for one of the 4 research projects. Total direct costs: $1,240,866 per

year for 5 years.

2001 “Assessment of lung function in mice.” R01 HL67273. Role: PI, $200,000 pa for 3 years.

This grant received a percentile ranking of 8.7.

2005 “Mechanics of acute lung injury.” R01 HL75593. Role: PI, $200,000 pa for 5 years. This

67

grant was funded with a percentile ranking of 5.2.

2006 “Assessment of lung function in mice.” Competitive continuation of R01 HL67273. Role: PI,

$250,000 pa for 4 years. This grant was funded a percentile ranking of 12.0.

2007 “Airway hyper-responsiveness: from molecule to organ.” R33 HL087788. Role: PI, $131,863

pa for 3 years. This grant received a score of 154, and is a collaboration with 4 other PI’s at

other universities (Michael Sanderson, PhD, University of Massachusetts Medical School;

Anne-Marie Lauzon, PhD, McGill University; James Sneyd, University of Auckland; Merryn

Tawhai, University of Auckland).

2010 “Airway hyper-responsiveness: from molecule to organ.” R01 HL103405. Role: PI, $ pa for 4

years. This grant received a score of ???, and is a continuation of 2007 R33 grant with 4 other

PI’s at other universities (Michael Sanderson, PhD, University of Massachusetts Medical

School; Anne-Marie Lauzon, PhD, McGill University; James Sneyd, University of Auckland;

Merryn Tawhai, University of Auckland).

D) Major Equipment Grants

1986 "Masspectrometer". (co-applicants: J. Milic-Emili, P.T. Macklem, C. Roussis, A. Grassino, J.

Martin, S. Gottfried, S. Newman and F. Bellemare) Canadian Medical Research Council

Major Equipment Grant $77,935.

1986 "A Dedicated Computer-Controlled Respiratory Mechanics Laboratory". (principal

investigator) Canadian Medical Research Council Major Equipment Grant $29,250.

1987 "Computer Facilities". (co-applicants: J. Milic-Emili, P.T. Macklem, A. Grassino, C.

Roussos, J. Martin, F. Bellemare, S. Gottfried, S. Magder and M. Ludwig) Canadian Medical

Research Council Major Equipment Grant $35,000.

1988 "Blood Gas Analyser". (co-applicants: J. Milic-Emili, P.T. Macklem, A. Grassino, C.

Roussos, F. Bellemare, M. Ludwig, S. Magder, J. Martin) Canadian Medical Research

Council Major Equipment Grant $36,500.

E) Operating Grants from Internal Agencies

1987 "The use of different gases to separate the effects of tissue viscoelasticity and ventilation

distribution on the mechanical behaviour of the respiratory system". (principal investigator)

Research and Education Fund of the Royal Victoria Hospital, Montreal, Quebec $11,500.

(finished)

1988 "Elucidation of interrupter technique for measuring respiratory system resistance through

simultaneous measurements of alveolar pressures with capsules". (principal investigator) The

EL/JTC Memorial Research Fund, $15,000. (finished)

1994 "A mobile patient monitoring system for respiratory mechanics." (principal investigator)

Montreal Chest Hospital Research Institute. $10,500

1994-95 Operating grant from the J.T. Costello Memorial Research Fund. (principal investigator)

$17,500.

1995-96 "The Development of the Mouse as Model of Respiratory Disease." J.T. Costello Memorial

Research Fund. $20,000. Co-applicants: D. Eidelman, Q. Hamid, M. Ludwig.

1995-96 "Confocal Microscopy". J.T. Costello Memorial Research Fund. $20,000. Co-applicants: D.

68

Eidelman, Q. Hamid.

2000 “Assessment of the risk of overinflation injury from measurements of respiratory system

mechanics in ARDS patients during mechanical ventilation.” Patient Oriented Pilot Project,

Fletcher Allen Health care, University of Vermont.. $6,200

2000 “Assessment of the risk of overinflation injury from measurements of respiratory system

mechanics during mechanical ventilation.” (principal investigator). Patient oriented research

pilot project award $6,400.

2011 “ “ (principal investigator). Pilot Project Award from the COBRE Phase III Grant at the

Vermont Lung Center.

F) Research Contracts

1995 Contract to develop a computer model of ozone uptake in human lungs. Health and Welfare

Canada $30,000 (Contract Reference No. 4823, Collator No. 1527, Project No. K281218)

1996 Contract to validate computer model of ozone uptake in human lungs. Health and Welfare

Canada $5,000

2001 Lung function in mouse models of pulmonary inflammation. Contract between AstraZeneca

Inc. and The University of Vermont to support Lennart Lundblad and operating expenses in

my laboratory. USD$90,363

69

TEACHING

A) Courses

McGill University

"Topics in Advanced Respiration" (516-508B), Department of Medicine: Since 1986 I have contributed

one or two 2 hr lectures per year to this course. The lectures were usually on the use of mathematical models

in respiratory physiology, although for the past two years I have also lectured on pulmonary dead space and gas

exchange. Attendance is typically 2-6 students taking the course for credit and 10-20 research students and

fellows auditing.

"Exercise Physiology" (552-502B), Department of Physiology: Since 1987 I have contributed a 2 hr lecture

on respiratory adaptations to exercise. Since 1993 I have contributed an additional 2 hr lecture on muscle

physiology. Attendance is 20-30 students.

"Selected Topics in Biomedical Engineering" (399-501), Biomedical Engineering Department: Since 1988

I have contributed a 3 hr lecture on bioengineering aspects of respiratory physiology.

"Biomedical Instrumentation and Measurement Technique" (399-503B), Biomedical Engineering

Department: This is a graduate level course that I designed and gave from 1988-96. It introduced students to

both the theory and practice of laboratory measurement in physiology and the medical sciences. As well as

running the course, I gave 12-15 hrs of lectures and oversaw the laboratory sessions which used software I

have written (ANADAT and LABDAT). The remaining lecture hours were given by other members of the

Biomedical Engineering Department.

"General Physiology" (552-202), Department of Physiology: Since 1988 I have contributed between 3 and 5

hrs of lectures on general respiratory physiology to classes of more than 100 students, as well as giving a

tutorial.

"General Physiology" (552-211D), Department of Physiology: In 1989 I contributed 7 hrs of lectures on

general respiratory physiology. Since 1990 I have contributed 2-4 hrs of lectures on general muscle

physiology.

"Physiological Systems for Biomedical Engineers" (399-511A), Department of Biomedical Engineering:

Since 1993 I have been organizer for this course which requires students to pass a general physiology course

give by the Physiology Department and then prepare an essay on a physiological topic of their choosing.

"Seminars in Biomedical Engineering", Department of Biomedical Engineering: In 1996 I took over

responsibility for organizing the departmental seminar series which involves creating the schedule. This course

can be taken for credit by students in the Biomedical Engineering Department.

“Experimental Physiology” (552-351B), Department of Physiology. In 1997 I began contributing 4 hrs of

lectures and 6 hrs of labs on experimental measurement technique to this course.

Medical Student Teaching: Since 1995 I have been contributing 4 hrs of lectures on respiratory gas

exchange to MED I students.

“The Respiratory Mechanic”, an international course on the estimation and interpretation of respiratory

mechanics, given at the Meakins-Christie Laboratories, October 4-5, 1998. Attended by 14 scientists from

Canada, USA and Taiwan.


Med II Respiratory Physiology, 2005 – 2007: I contribute a lecture on pulmonary gas exchange to the course

work for Med II students.

70

MPBP 295 Human Physiology II, 2007: I contribute six 1.5 hr lectures on respiratory physiology to this

graduate level course on general physiology.

CLBI 295F Basic Principles of Lung Biology, 2005: I contributed 2 lectures entitled “Respiratory Mechanics

I” and “Gas Exchange – Respiratory Mechanics II”.

EE227 Biomedical Measurements, Instrumentation and Systems, 2002 - 2004: I presented a lecture on

measurement techniques in respiratory medicine and physiology.

ME 301 Biomedical Engineering, 2005 – 2007: I give students a 1.5 hr lecture on lung biomechanics and a

tour of my laboratory in the Vemont Lung Center.

Mathematics for Biomedical Scientists, 2003: I gave a 7-week course on biomathematics to members of the

UVM Pulmonary Division, and prepared 4 papers from the presented material that were published in Coronary

Artery Disease with Dr. B. Sobel.

CLBI 395 Toward Career Success in Science, 2007: I contribute 2 lectures entitled “Animal Care and Use

Committee” and “Getting Published, Peer Review, Being a Reviewer”.

The Respiratory Mechanic, 2000 - 2002: I organized and lectured in a 2-day international course on the

theory and practice of respiratory mechanics measurement.

Workshop on Scientific Writing, 2002: I co-ran a workshop on scientific writing under the auspices of

UVM’s Center of Biomedical Research Excellence in lung biology.

ME312/295 Advanced Bioengineering Systems, Spring 2012, 13, 14: I am instructor for this graduate-level

course which is a core requirement for the Bioengineering PhD Program.

ME207 Bioengineering, Fall 2013: I am instructor for this course which is part of the biomedical

concentration in Mechanical Engineering

B) Supervision of Post-doctoral Fellows

Peter Sly, MD Dr. Sly was an MRC Fellow at the Meakins-Christie Laboratories for 2 years

from 1985-87. He worked exclusively with me during that time,principally

on the interrupter technique for measuring respiratory system resistance. Our

collaboration is still continuing. Dr. Sly is now Head of Physiological

Sciences at the Western Australia Research Institute in Child Health in

Perth, Australi.

Shuichi Okubo, MD Dr. Okubo was a fellow at the Meakins-Christie Laboratories for 2 years

from 1985-87, and worked with me about 50% of the time, principally on

the use of a fast valve for the interrupter technique for measuring respiratory

system resistance. Dr. Okubo is now a practicing chest physician in Japan.

Karen Brown, MD Dr. Brown was a fellow at the Meakins-Christie Laboratories from 1985-87,

and worked with me about 75% of the time, on both the interrupter

technique for measuring respiratory system resistance and a modeling study

of the effects of endotracheal tube blockage on respiratory mechanics. Dr.

Brown is now a staff anesthetist at the Montreal Children’s Hospital.

Tetsuo Kochi, MD Dr. Kochi was a fellow at the Meakins-Christie Laboratories for 2 years from

1985-87, and worked with me about 20% of the time, on various aspects of

modeling respiratory system mechanics. Dr. Kochi was an anesthetist at

Chiba University Hospital, Japan.

71

Felix Shardonofsky, MD Dr. Shardonofsky was a fellow at the Meakins-Christie Laboratories for 3

years from 1986-88. He worked with me about 50% of the time on the

experimental determination of the degree of quasi-static pressure-volume

hystersis in the respiratory system of a normal living dog. Dr. Shardonofsky

is now a staff pediatrician at the University of Texas Southwestern, Dallas,

Texas.

Tadashi Abe, MD Tadashi worked with me for the final three months of his stay at the

Meakins-Christie Laboratories, in 1988. He was instrumental in developing

the closed-chest alveolar capsule technique. Dr. Abe is now associate

professor of medicine at Kitasato University, Japan.

Jiro Sato, MD Dr. Sato was a fellow at the Meakins-Christie Laboratories for 2 years from

1987-89, and worked full time with me. His work was principally on the

modeling of low-frequency respiratory system mechanics and the effects of

gas density and viscosity. Dr. Sato is now a staff anesthetist at Chiba

University Hospital, Japan.

Bruce Davey, PhD Dr. Davey is an Electrical Engineer and was a fellow at the Meakins-Christie

Laboratories for 18 months from1989-91. He worked full-time with me for

18 months on two main projects: identifying lung mechanics by applying

forced oscillations in flow through an alveolar capsule, and measuring the

high-frequency content of the canine phrenic electroneurogram. Dr. Davey

is now a senior engineer with ISG Inc., a Toronto-based medical imaging

software company.

Bela Suki, PhD Dr. Suki is a phyicist from Hungary and was a fellow at the Meakins-

Christie Laboratories for 10 months during 1990. He worked full-time with

me on nonlinear models of lung tissue viscoelasticity and airway resistance.

Dr. Suki is now an associate professor of biomedical engineering at Boston

University.

Oleg Reich, MD Dr. Reich is a pediatric cardiologist from Prague, Czechosolvakia and was a

fellow at the Meakins-Christie Laboratories for the year of 1992. He worked

on the measurement of breathing patterns in infants coming out of anesthesia

and during CO2 rebreathing tests. This work was done in collaboration with

Dr. Karen Brown of the Department of Anesthesiology, The Montreal

Children's Hospital. Dr. Reich received a 6-month salary award ($25,000)

from the MRC as a visiting eastern European scientist. He is now chief of

pediatric nuclear medicine at Charles Univesity Hospital, Prague, Czech

Republic.

Zsolt Balassy, PhD Dr. Balassy is a mathematician from Budapest, Hungary and was a fellow at

the Meakins-Christie Laboratories for two years from 1992 to 1994. He

worked full-time with me on identifying local lung impedance using forced

oscillations through alveolar capsules, and on the development of a

comprehensive model of the airway tree impedance. Dr. Balassy is now

working in Budapest.

Michiaki Mishima, MD Dr. Mishima is a thoracic surgeon from Kyoto, Japan and was a fellow at the

Meakins-Christie Laboratories from 1992 to 1994. He worked full-time with

me on identifying local lung impedance using forced oscillations through

alveolar capsules, and on software to analyse computed tomographic slices

of lung. Dr. Mishima is now professor of medicine and head of the

72

Department of Chest Medicine, Kyoto University, Japan.

William Thorpe, PhD Dr. Thorpe is an electrical engineer from New Zealand and was a fellow at

the Meakins-Christie Laboratories for two years from 1994 to 1996. He

worked full-time with me on a distributed model of the lung in order to

simulate the time-course of impedance changes during bronchoconstriction,

and on a model of ozone uptake in the lungs. Dr. Thorpe is now a senior

lecturer at the University of Auckland, New Zealand.

Tadashi Nemoto, MD Dr. Nemoto is a thoracic surgeon from Japan and was a fellow at the

Meakins-Christie Laboratories for two years from 1994 to 1996. He worked

full-time with me on a fuzzy logic system for weaning patients from

mechanical ventilators. Dr. Nemoto is now chief of thoracic surgery, Shiga

City Hospital, Japan.

Norihiro Shinozuka, MD Dr. Shinozuka is an anesthetist from Chiba, Japan and started as a fellow at

the Meakins-Christie Laboratories in 1995 and left for a anesthesiologist

position in Japan in 1997. He worked on measuring pulmonary impedance

in dogs during induced bronchoconstriction

Andrew Adler, PhD Dr. Adler is an electrical engineer from Canada and started as a fellow at the

Meakins-Christie Laboratories in 1996 and left for a post-doctoral position in

Denver in 1997. He worked on the use of electrical impedance tomography

in thoracic imaging. He also worked jointly with me and Dr. David

Eidelman, also of the Meakins-Christie Laboratories, on the processing of

micrscopic images of lung parenchyma. Dr. Adler is now an assistant

professor or biomedical engineering at the University of Ottawa, Canada.

Toyohiro Hirai, MD Dr. Hirai is a thoracic surgeon from Kyoto, Japan who worked in my

laboratory from 1997 - 1999. He is studied bronchial reactivity in small

animals. Dr. Hirai has returned to Japan and is now a researcher and

physician at Kyoto University.

George Hatzakis, PhD Dr. Hatzakis is a biomedical engineer from Athens, Greece who worked with

me from 1997-1999 on fuzzy logic applications in the management of

mechanically ventilated patients in the intensive care unit. Dr. Hatxzakis is

now an assistant professor at McGill University, Montreal, Canada.

Yasutaka Takubo, MD Dr. Takubo is a thoracic surgeon from Kyoto, Japan. He worked with me in

1999 and measured respiratory system mechanics in small animals exposed

to cigarette smoke, in collaboration with Dr. Manuel Cosio of the Royal

Victoria Hospital and McGill University. Dr. Takubo is now a researcher

and physician at Kyoto University in Japan.

Gilman B. Allen, MD Dr. Allen began working with me at the University of Vermont on animal

models of acute lung injury during his third year of pulmonary/critical care

fellowship in 1999. In 2004 he was awarded a K08 from the NIH, under my

mentorship, to continue his career development as a clinician scientist. He is

currently an Assistant Professor of Medicine at the University of Vermont.

Mohammed Turki, MD Dr. Turki worked under my supervision during his research rotation in 2003-

2004 as part of his Fellowship in Pulmonary/Critical Care Medicine at the

University of Vermont/Fletcher Allen Health Care. His project involved

studying the pressures generated at the airway opening during mechanical

ventilation. Dr. Turki now works in private practice in the United States.

73

Kapilkumar Patel, MD Dr. Patel worked under my supervision during his research rotation in 2006-

2007 as part of his Fellowship in Pulmonary/Critical Care Medicine at the

University of Vermont/Fletcher Allen Health Care. His project involved

studying the calculation of the rapid shallow breathing index in patients in

the intensive care unit. Dr. Patel moved on to do a transplant fellowship at

Stanford University.

Ana Cojacaru, MD Dr. Cojacaru obtained her MD in Romania and recently immigrated to the

US to continue her medical training. She completed a year of post-doctoral

research training from May 2006 to June 2007 with me before moving on to

a residency position in Boston.

Ron Anafi, MD, PhD Dr. Anafi worked 75% time as a post-doctoral research fellow in my

laboratory from July 2007 to June 2008. He then moved to Philadelphia to

start fellowship training in sleep medicine. Dr. Anafi’s research involved

modeling airway smooth muscle mechanics and investigating neural network

models of inflammation.

Konstantin Tetenev, MD Dr. Tetenev arrived in my laboratory in September of 2007 on a Fulbright

Fellowship from the Siberian Medical University, Russia. He worked for two

years in my laboratory working on mouse models of acute lung injury.

Adrian Seah, MD Dr. Seah is a second-year surgical resident working in my laboratory for a

year on animal models of ventilator-induced lung injury. In June 2010 he

returned to his clinical training as a resident.

Baoshun Ma, PhD Dr. Ma arrived in my laboratory in October 2009 with a PhD in biomedical

engineering from the University of Iowa and post-doctoral training in at

Boston University and the University of California San Diego. He has been

working on computational modeling of lung function in acute lung injury

and asthma, and has just been promoted to the position of Research

Associate in the University of Vermont College of Medicine.

Bradford Smith, PhD Dr. Smith arrived in my laboratory in 2011 after completing a PhD in

biomedical engineering at Tulane University. He is currently working on

computational and experimental models of acute lung injury.

Binh Nguyen, MD Dr. Nguyen is a fellow in Pulmonary/Critical Care Medicine at the

University of Vermont who has been doing his research rotations in my

laboratory since 2011, working on methods for setting the parameters

mechanical ventilation based on fuzzy logic.

Ali Al-Alwan, MD Dr. Al-Alwan is a fellow in Pulmonary/Critical Care Medicine at the

University of Vermont who did his research rotation in my laboratory 2012-

13, working on the use for the forced oscillation method to study lung

function in obese asthmatic patients.

Jad Harb, MD Dr. Harb has recently started his research rotation in my laboratory working

on the collection and analysis of complex time series recordings of blood

pressure in the intensive care unit.

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C) Supervision of Graduate Students

Anne-Marie Lauzon Anne-Marie Lauzon started graduate studies under my supervision in

January 1989, with a degree in Physics and Physiology from McGill

University. She completed her PhD (Dean's List) in physiology in 1993. Her

research project consisted of the development of a recursive least squares

method for obtaining continuous estimates of respiratory resistance and

elastance over long periods of time. She applied this technique to the study

of the time-course of induced bronchoconstriction in dogs. Dr. Lauzon is

currently an associate professor in the Meakins-Christie Laboratories of

McGill University, Montreal, Canada.

Gail Dechman Gail Dechman started graduate studies under my supervision in 1989, after

training as a physiotherapist and working professionally for ten years. She

completed her PhD in Physiology in 1994. Her project consisted of a study

of a dog model of pleural effusion using respiratory mechanics estimation

techniques and computed tomography. Dr. Dechman is currently an

Associate Professor at Dalhousie University, Halifax, Canada.

Geoffrey Maksym Geoffrey Maksym started graduate studies under my supervision in 1991,

with a degree in engineering physics from Nova Scotia. He completed a

masters degree in Electrical Engineering under my supervision in 1993, in

which he developed a computer-controlled mechanical testing rig for soft

tissue. He received an NSERC graduate scholarship, and completed his

PhD in 1997 in biomedical engineering on the complex rheology of lung

tissue. Dr. Maksym is currently an associate professor of biomedical

engineering and department chair at Dalhousie University, Halifax, Canada.

Thomas Schuessler Thomas Schuessler started graduate studies under my supervision in 1991,

with a degree in electronic engineering from Kahlsruhe University,

Germany. He completed his masters degree in biomedical engineering

(Dean’s list) under my supervision in 1993, for which he developed a

mechanical ventilator/oscillator for small animals. He completing his PhD in

in 1997 biomedical engineering on electrical impedance tomography image

reconstruction of the thorax, and on models of patients on mechanical

ventilators. He is currently President of SCIREQ Scientific Respiratory

Equipment, Inc., a start-up company we formed together to produce and

market the small animal ventilator under the name flexiVent.

Robin Prassad Robbin Prassad began graduate work under my supervision toward a masters

degree in Biomedical Engineering in 1993. Working part-time, he completed

his masters thesis on computer models that combine respiratory mechanics

and gas exchange, in order to test hypothesis about control of breathing in

1997. He is currently a practicing radiologist.

Mohsen Ahmadi Mohsen began graduate studies under my supervision toward a PhD in

biomedical engineering in 1995. He developed a computer-controlled

mechanical ventilator for intensive care patients, and completed his PhD in

1999. He has returned to Iran for a career in industry.

Rute Gomes Rute began graduate studies under my supervsion toward a PhD in

experimental medicine in 1996. She has a degree in electrical engineering

and a masters degree in physiology the Federal University of Rio de Janiero,

and worked on the measurement of respiratory mechanics during

75

develoopment in small animals (rats and mice). She received her PhD from

McGill University in 2002.

Eve Bijaoui Eve is did her PhD in biomedical engineering under the France-Quebec co-

tutelle program (jointly at Universite Joseph Fourier in Grenoble and

Unversite de Montreal). She worked under my supervision from 1996 on

methods for estimating respiratory mechanics.She received her PhD in 2001,

and is now working as a biomedical scientist in France.

Shalini Veerasami Shalini completed her masters degree with me in Biomedical Engineering in

2001. Her project involved constructing a computer model of the cardio-

vascular system, in collaboration with Dr. Shelley Magder, Director of the

Critical Care Division at the Royal Victoria Hospital in Montreal. She is now

a practicing physician.

Lennart Lundblad Lennart worked on his PhD under my supervision at the University of

Vermont, and was awarded his PhD from the University of Lund, Sweden,

in 2005. Prior to that, he spent many years as a research pharmacologist with

AstraZeneca in Lund, Sweden. His PhD research involved the development

and application of novel methods for measuring lung function in mice. Dr.

Lundblad is now a Research Assistant Professor in the Vermont Lung

Center, University of Vermont.

Henrique Moriya Henrique spent a 1 year period (Oct 2000-Oct 2001) in my laboratory,

working toward his PhD, investigating mathematical models of respiratory

mechanics. He obtained his PhD from the University of Sao Paulo, Brazil, in

2003. He is now an assistant professor of biomedical engineering at the

University of Sao Paulo, Brazil.

Sonia Khirani Sonia completed here PhD in biomedical engineering at the Universite

Joseph Fourier in Grenoble, France, in 2003, after spending 8 months (April

– November 2001) doing research in my laboratory studying flow limitation

in mice. She is now a biomedical scientist working in Paris, France.

Chris Massa Chris completed a masters degree in biomedical engineering under my

supervision at the University of Vermont in 2008. He worked on a project

involving fitting a computational model of lung recruitment and

derecruitment to data collected from mice with acute lung injury. He is now

in medical school in New Jersey in the MD-PhD program.

Ben Schwartz Ben completed a masters degree in biomedical engineering at the University

of Vermont under my supervision in 2009. He worked on the modeling of

lung mechanics in mice, with a focus on the important of airway compliance

for lung input impedance in mouse models of lung disease. He is now

working towards his PhD in biomedical engineering at the University of

Illinois Chicago.

Nirav Daphtary Nirav completed a masters degree in biomedical engineering at the

University of Vermont under my supervision in 2009. His project was the

development of a method for measuring the input impedance of the lungs in

patients during targeted breathing maneuvers. He is now a technician in the

Vermont Lung Center.

Keryn Palmer Keryn completed a masters degree in biomedical engineering at the

University of Vermont under my supervision in 2012. Her project

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investigated deconvolution methods for improving the resolution of multi-

electrode intra-cardiac recordings of electrical activity in the heart.

Hasan Guler Hasan is a PhD student from Turkey who spend 6 months in my laboratory

in 2010 working of the development of algorithms for controlling

mechanical ventilation based in fuzzy logic. He is now back in Turkey

completing his PhD in electrical engineering.

Joshua Pothen Joshua is an MD-PhD student at the University of Vermont who has been

working toward a PhD in bioengineering under my supervision since mid

2011. His project is to apply agent-based modelling to the understanding of

lung immunology, with a particular focus on allergic inflammation.

Bryce Benson Bryce Benson began his PhD in bioengineering in mid 2011, jointly

supervised by Dr. Peter Spector, Cardiology Division. Bryce’s project is to

study the complex dynamics of cardiac excitation in atrial fibrillation using

computational models.

D) Supervision of Undergraduate Students

Fernando Donoso Fernando worked in my lab during the summer of 1990 after obtaining his

BS in Physiology. He constructed laboratory equipment.

Uta Prechelt Uta did a 6 week internship in my laboratory during 1992, as part of her

course requirements for a degree in Electrical Engineering from the

University of Karlsruhe, Germany. She worked on the design of electronic

signal conditioners.

Erik Lenz Erik did a 6 week internship in my laboratory during 1993, as part of his

course requirements for a degree in Electrical Engineering from the

University of Karlsruhe, Germany. He worked on the design of electronic

circuit boards.

Usama Kanaan This group of six McGill mechanical engineering students completed a

Ben Urovitch full-year project under my supervision on the mechanical redesign of the

Agnes von Hahn Small Animal Ventilator originally developed by my graduate student

David Sefkind Thomas Schuessler.

Andrea Russell

Adrian Field

Ben Urovitch Ben is a mechanical engineering student who worked in my laboratory

during the summer of 1996 on a device for measuring respiratory mechanics

in small animals. He was part of a 6-member team of mechanical

engineering students who had worked on the device as part of their design

course requirements the previous academic year.

Kelly-Anne McKeown Kelly Anne worked on animal models of bronchial responsiveness during

the summer of 1997, and pursued an undergraduate project in Physiology

under my supervision the subsequent academic year.

David Baesl David is an engineering student at Queen’s University in Kingston, Canada,

who worked in my laboratory during the summer of 2004 on the

development of a video method for imaging thoracic movement in mice.

Timoth Leclair Timothy is a qualified respiratory therapist currently pursuing medical

77

studies at the University of Vermont. He has been employed in my

laboratory since 2002, working on the development and assessment of

mouse models of acute lung injury.

Michael Kavouksorian Michael is currently pursuing hid MBA at the University of Vermont.

During the summer of 2006 he worked in my laboratory measuring the

dimensions of the airways of the mouse lung from micro-CT scans.

Paul Haake Paul is a computer science student at the University of Vermont who is

working over the summer of 2007 on a computational model of the lung.

Katherine Accomando Katie is a mechanical engineering student at the University of Vermont who

worked in my laboratory during the summer of 2008, as a work-study

student throughout the following academic year, and again during the

summer of 2009. She is working on my new system for noninvasive

measurement of lung function in mice known as unrestrained video-assisted

plethysmography.

Chelsea Stevenson Chelsea is a mechanical engineering student at the University of Vermont

working in my laboratory for the summer of 2009 on the measurement of

lung impedance in mice following administration of aerosols of smooth

muscle agonist.

Kara Grant Kara is a biological engineering student at Cornell University who is

working in my laboratory during the summer on 2009 on the measurement of

lung function in mouse models of acute lung injury and ventilator-induced

lung injury.

David Bernstein David is a mechanical engineering undergraduate student at the University

of Vermont who worked through the summer of 2010 and throughout the

following academic year on the coding of computational models of lung

function.

Erika Martinez Erika studied at the University of Puerto Rico and did a summer research

internship in my laboratory in 2011. Her project was to develop an agent-

based model of allergic inflammation in the lung.

78

SERVICES TO THE UNIVERSITY AND SCIENTIFIC COMMUNITIES

A) Committees

McGill University

1994-96 Institutional Review Board, Royal Victoria Hospital, Montreal.

1996-99 Institutional Review Board, McGill University Faculty of Medicine, Montreal.

1996 McGill Association of University Teachers, Software Policy Committee


2001 - 2003 Chair, Institutional Animal Care and Use Committee

2003 - 2007 Member., Institutional Animal Care and Use Committee, and Chair of the Policy &

Procedures Sub-Committee

2007 Chair of search committee for a new member of the bioengineering program in the

College of Engineering and Mathematical Sciences. Member of recruitment

committee for a new Chief of Pulmonary and Critical Care Medicine

2006 Member of committee instigated by Dean of Medicine John Evans to investigate the

formation of a cross-college program in bioengineering and computational biology

2009-2011 Interim co-director of new PhD Program in Bioengineering at the University of

Vermont

2009 Member of committee to formulate a spire of excellence in Biomedical Science and

Bioengineering

2010 Member of the Complex Systems Steering Committee

2010 Graduate Coordinator, Biomedical Engineering Program, College of Engineering and

Mathematical Sciences

2011 Founding Graduate Coordinator for Bioengineering PhD Program

2012 Chair of search committee for new Chair of Computer Science Department

National

2004 - 2006 Member of the Program Committee of the Structure/Function Assembly of the

American Thoracic Society

2010 - 2012 Chair-elect and then Chair of the Program Committee Structure/Function Assembly

of the American Thoracic Society

2010 Member of the Core Curriculum Task Force of the American Thoracic Society

2011 Co-Chair, Respiratory Engineering Track, Annual Meeting of the Biomedical

Engineering Society

2011 Session chair for “Computational modeling of lung mechanical function” for the

IEEE Engineering in Medicine and Biology Meeting, Boston, Aug 30 – Sep 3, 2011.

2014 Vermont representative for the Northern New England Chapter of the IEEE

Engineering in Medicine & Biology Society

79

B) Peer Reviewing

1994 - 2008 Member of Editorial Board of Respiration Physiology

1997 - 2001 Associate Editor for the European Respiratory Journal

1997 - 2000 Member of the Biomedical Engineering Committee of the Medical Research Council

of Canada

2001- present Member of Editorial Board of the Journal of Applied Physiology

2002 - 2006 Member of Editorial Board of the American Journal of Respiratory and Critical

Care Medicine

2004 Member of NIH Special Emphasis Panel for the Roadmap Initiative: “Centers for

Biomedical Computing” and “Exploratory Centers for Interdisciplinary Research”

2006 Chair of ad-hoc NIH study section to review a program project grant proposal.

2007 Member of two ad-hoc study sections reviewing SBIR grant proposals.

2008 Ad-hoc reviewer for RIBT study section of the NIH

2009 - 2014 Associate Editor for the Journal of Applied Physiology

2011 – present Member of the Editorial Board for the Journal of Clinical Monitoring and

Computing

2012 – present Member of Editorial Board of CRC Critical Reviews in Biomedical Engineering

2013 - present Member of RIBT study section for National Institutes of Health

2014 - present Deputy Editor for the Journal of Applied Physiology

I have been a regular reviewer for the Medical Research Council of Canada, the Fonds de la Recherches en

Sante du Quebec, the British Columbia Health Foundation, the University of Maryland Agricultural

Experiment Station, the Australian National Health and Medical Research Council, and the National Institutes

of Health.

I have acted as referee for a number of journals, the main ones being European Respiratory Journal,

Respiration Physiology, American Journal of Respiratory and Critical Care Medicine, IEEE Transactions on

Biomedical Engineering, Journal of Applied Physiology, and Annals of Biomedical Engineering. I review 30-

50 papers per year.

C) Technology Transfer

I produced a general-purpose data analysis package called ANADAT, with an associated data acquisition

program called LABDAT and a specialized software module for analysing respiratory data called ABREATH.

In 1991, following an arrangement with McGill University, I set up a company together with my wife, Nancy

MacGregor, in order to market this software to university researchers and companies interested in quantitative

physiological research. The company, RHT-Infodat, was incorporated nationally and distributed nearly 100

copies of ANADAT to researchers in 16 countries. RHT-InfoDat, Inc. was an industrial affiliate of

Inspiraplex, the Respiratory Health Network of Centres of Excellence.

In 1997 I was involved with the establishment of a second company, SCIREQ Scientific Respiratory

Equipment, Inc. of Montreal. SCIREQ is a spin-off company of the Respiratory Health Network of Centres of

Excellence (Inspiraplex). A former graduate student of mine, Dr. Thomas Schuessler, is CEO of SCIREQ,

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whose mission is to manufacture and market high-tech scientific instruments for respiratory research.

SCIREQ’s main product currently is a computer-controlled device for measuring respiratory mechanics in

small animals. The device, called the flexiVent, was invented by Dr. Schuessler and myself. SCIREQ also

makes and markets other devices. I left SCIREQ in 2002.

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