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© 2016 Jefferies LLC. Member SIPC. SAVE THE DATE NOVEMBER 16-17, 2016 Waldorf Hilton Aldwych London WC2B 4DD, UK Jefferies 2016 London Healthcare Conference You are invited to attend the Jefferies 2016 London Healthcare Conference taking place November 16-17 at the Waldorf Hilton in London. Now in its seventh year, the Jefferies Conference is the largest healthcare-dedicated conference in Europe. Last year, we hosted over 300 participating companies, 1,200 attendees and 3,700 business-to-business and investor meetings. Our event will feature leading public and private companies from the pharmaceuticals, biotechnology, generics, consumer health, animal health, medical technology and healthcare services sectors from the United States, Europe, Africa, Middle East, Latin America, Russia, India, Israel, China and Japan. The two-day event will include concurrent tracks of company presentations, thematic panel discussions, and 1x1/small-group meetings. This global gathering of leading healthcare executives and institutional, private equity and venture capital investors will address near- and long-term investment opportunities and discuss the mechanisms driving global healthcare. TO REGISTER, please contact your Jefferies representative. FOR QUESTIONS, please email [email protected]. INVITATION NOVEMBER 16-17, 2016 Waldorf Hilton Aldwych London WC2B 4DD, UK

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© 2016 Jefferies LLC. Member SIPC.

SAVE THE DATE NOVEMBER 16-17, 2016 Waldorf Hilton

Aldwych

London WC2B 4DD, UK

Jefferies 2016 London Healthcare Conference

You are invited to attend the Jefferies 2016 London Healthcare Conference taking place

November 16-17 at the Waldorf Hilton in London.

Now in its seventh year, the Jefferies Conference is the largest healthcare-dedicated

conference in Europe. Last year, we hosted over 300 participating companies,

1,200 attendees and 3,700 business-to-business and investor meetings. Our event

will feature leading public and private companies from the pharmaceuticals,

biotechnology, generics, consumer health, animal health, medical technology

and healthcare services sectors from the United States, Europe, Africa, Middle East, Latin

America, Russia, India, Israel, China and Japan.

The two-day event will include concurrent tracks of company presentations, thematic

panel discussions, and 1x1/small-group meetings. This global gathering

of leading healthcare executives and institutional, private equity and venture capital

investors will address near- and long-term investment opportunities and discuss the

mechanisms driving global healthcare.

TO REGISTER, please contact your Jefferies representative.

FOR QUESTIONS, please email [email protected].

INVITATION NOVEMBER 16-17, 2016 Waldorf Hilton Aldwych London WC2B 4DD, UK

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

3SBio Inc. SEHK:1530 Presenting & Meetings Biotechnology Yes Tbd Tbd Tbd

Ablynx NV ENXTBR:ABLX Presenting & Meetings Biotechnology Yes No No Edwin Moses, CEO

Abpro Corporation Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Ian Chan, CEO

Acacia Pharma Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Julian Gilbert, CEO

Actelion Ltd. SWX:ATLN Presenting & Meetings Biotechnology Yes Yes No Andrew Weiss, Head of IR & Corp Communications

Adaptimmune Therapeutics plc NasdaqGS:ADAP Meetings Only Biotechnology Yes No No 1x1s: James Noble, CFO

ADIENNE Pharma & Biotech Private Presenting & Meetings Biotechnology Yes No Yes Antonio Francesco Di Naro, Chairman & President

Adocia Societe Anonyme ENXTPA:ADOC Presenting & Meetings Biotechnology Yes Yes No Gerard Soula, CEO

Advaxis, Inc. NasdaqCM:ADXS Presenting & Meetings Biotechnology Yes No No Daniel O'Connor, President & CEO

Adverum Biotechnologies, Inc. NasdaqGM:ADVM Presenting & Meetings Biotechnology Yes No No Paul Cleveland, CEO

Affimed N.V. NasdaqGM:AFMD Presenting & Meetings Biotechnology Yes Yes No Adi Hoess, CEO

Agenus Inc. NasdaqCM:AGEN Presenting & Meetings Biotechnology Yes No No Garo Armen, CEO

Alexion Pharmaceuticals, Inc. NasdaqGS:ALXN Meetings Only Biotechnology No No Yes Tbd

Alkermes plc NasdaqGS:ALKS Presenting & Meetings Biotechnology Yes No No Richard Pops, CEO

Alnylam Pharmaceuticals, Inc. NasdaqGS:ALNY Presenting & Meetings Biotechnology Yes No No DA Gros, SVP & Chief Business Officer

Amarin Corp Plc NasdaqGM:AMRN Presenting & Meetings Biotechnology Yes No Yes John Thero, CEO

Anima Biotech Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Yochi Slonim, Co-Founder & CEO

Apitope International N.V. Private Meetings Only Biotechnology Yes Yes Yes Tbd

arGEN-X N.V ENXTBR:ARGX Meetings Only Biotechnology Yes No No 1x1s: Tim Van Hauwermeiren, CEO

Ariad Pharmaceuticals Inc. NasdaqGS:ARIA Presenting & Meetings Biotechnology Yes No No Paris Panayiotopoulos, CEO & President

Array BioPharma, Inc. NasdaqGM:ARRY Presenting & Meetings Biotechnology Yes No No RON SQUARER, CEO

Ascendis Pharma A/S NasdaqGS:ASND Meetings Only Biotechnology Yes Yes Yes 1x1s: Scott Smith, CFO

ASIT biotech s.a. ENXTBR:ASIT Meetings Only Biotechnology Yes No No 1x1s: Thierry Legon, CEO

ASLAN Pharmaceuticals Pte. Ltd. Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Carl Firth, CEO

AveXis, Inc. NasdaqGS:AVXS Presenting & Meetings Biotechnology Yes No No Sean Nolan, President & CEO

Axovant Sciences Ltd NYSE:AXON Presenting & Meetings Biotechnology Yes No No Vivek Ramaswamy, CEO

Basilea Pharmaceutica International SWX:BSLN Presenting & Meetings Biotechnology Yes No No Ronald Scott, CEO

Bavarian Nordic A/S CPSE:BAVA Presenting & Meetings Biotechnology Yes No No Paul Chaplin, President & CEO

Bellicum Pharmaceuticals, Inc. NasdaqGM:BLCM Presenting & Meetings Biotechnology Yes No No Thomas Farrell, President & CEO

BioInvent International AB OM:BINV Meetings Only Biotechnology Yes Tbd Tbd Tbd

BioMarin Pharmaceutical Inc. NasdaqGS:BMRN Presenting & Meetings Biotechnology Yes No Yes Joshua Grass, SVP, Business & Corp Development

BioSpecifics Technologies Corp. NasdaqGM:BSTC Meetings Only Biotechnology Yes No Yes Tbd

Cantargia AB OM:CANTA Meetings Only Biotechnology Yes Tbd Tbd Tbd

Cell Medica Limited Private Meetings Only Biotechnology Yes No Yes 1x1s: Gregg Sando, CEO

Cellectis S.A. NasdaqGM:CLLS Presenting & Meetings Biotechnology Yes Yes No Andre Choulika, Chairman & CEO

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Cellular Therapeutics Ltd Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Neill Mackenzie, Chairman

Celyad SA ENXTBR:CYAD Meetings Only Biotechnology Yes Yes Yes 1x1s: Christian Homsy, CEO

Chiasma, Inc. NasdaqGS:CHMA Meetings Only Biotechnology Yes Yes Yes 1x1s: Mark Fitzpatrick, President & CEO

Chronos Therapeutics Ltd. Private Meetings Only Biotechnology Yes No Yes 1x1s: Huw Jones, CEO

Circassia Limited LSE:CIR Meetings Only Biotechnology Yes No No 1x1s: Steven Harris, CEO

Coherus Biosciences, Inc. NasdaqGM:CHRS Presenting & Meetings Biotechnology Yes Yes No Denny Lanfear, President & CEO

Concert Pharmaceuticals, Inc. NasdaqGM:CNCE Presenting & Meetings Biotechnology Yes No No James Cassella, Chief Development Officer

CytomX Therapeutics, Inc. NasdaqGS:CTMX Presenting & Meetings Biotechnology Yes No No Sean McCarthy, President & CEO

DBV Technologies S.A. ENXTPA:DBV Presenting & Meetings Biotechnology Yes Yes No Susanna Mesa, SVP, Strategy

DelSiTech Ltd. Private Meetings Only Biotechnology No No Yes 1x1s: Cora Griffin, Business Development Director

DS Biopharma Private Meetings Only Biotechnology Yes Tbd Tbd Tbd

Eagle Pharmaceuticals Inc. NasdaqGM:EGRX Presenting & Meetings Biotechnology Yes Yes No Scott Tarriff, President & CEO

Edge Therapeutics, Inc. NasdaqGS:EDGE Presenting & Meetings Biotechnology Yes No No Brian Leuthner, President & CEO

ERYTECH Pharma ENXTPA:ERYP Presenting & Meetings Biotechnology Yes Yes Yes Gil Beyen, Chairman & CEO

Exonate Limited Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Catherine Beech, CEO

Fate Therapeutics, Inc. NasdaqGM:FATE Meetings Only Biotechnology Yes Yes No 1x1s: Scott Wolchko, CEO

Flex Pharma, Inc. NasdaqGM:FLKS Presenting & Meetings Biotechnology Yes No No Christoph Westphal, Chair, President & CEO

F-star Biotechnology Private Meetings Only Biotechnology Yes No Yes 1x1s: Tolga Hassan, CFO

Galapagos NV ENXTAM:GLPG Presenting & Meetings Biotechnology Yes No No Andre Hoekema, SVP

Genenta Science s.r.l. Private Meetings Only Biotechnology Yes Tbd Tbd Tbd

GeNeuro SA ENXTPA:GNRO Meetings Only Biotechnology Yes No Yes 1x1s: Jesus Martin-Garcia, CEO

Genmab AS CPSE:GEN Presenting & Meetings Biotechnology Yes No No Jan van de Winkel, President & CEO

GlycoMimetics, Inc. NasdaqGM:GLYC Presenting & Meetings Biotechnology Yes No No Rachel King, CEO

Hansa Medical AB OM:HMED Meetings Only Biotechnology Yes Yes No 1x1s: Göran Arvidson, CEO

Horizon Discovery Group plc AIM:HZD Meetings Only Biotechnology Yes Yes Yes 1x1s: Chris Claxton, VP, IR & Corp Communications

Ignyta, Inc. NasdaqCM:RXDX Presenting & Meetings Biotechnology Yes Yes Yes Jacob Chacko, CFO

Immune Design Corp. NasdaqGM:IMDZ Presenting & Meetings Biotechnology Yes No No Carlos Paya, President & CEO

Intellia Therapeutics Inc. NasdaqGM:NTLA Presenting & Meetings Biotechnology Yes No No Nessan Bermingham, CEO

Kadmon Holdings, LLC NYSE:KDMN Presenting & Meetings Biotechnology Yes No Yes Harlan Waksal, President & CEO

Kamada Ltd. TASE:KMDA Meetings Only Biotechnology Yes Yes Yes 1x1s: Amir London, CEO

Karyopharm Therapeutics, Inc. NasdaqGS:KPTI Presenting & Meetings Biotechnology Yes No No Michael Kauffman, CEO

KD-Pharma Bexbach GmbH Private Meetings Only Biotechnology Yes Tbd Tbd Tbd

Kite Pharma, Inc. NasdaqGS:KITE Presenting & Meetings Biotechnology Yes No No Arie Belldegrun, Chairman, President & CEO

Kymab Limited Private Meetings Only Biotechnology Yes No Yes 1x1s: David Chiswell, CEO

Lexicon Pharmaceuticals, Inc. NasdaqGS:LXRX Meetings Only Biotechnology Yes No No 1x1s: Jeffrey Wade, EVP, Corp & Administrative Affairs & CFO

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Lysogene SAS Private Meetings Only Biotechnology Yes Yes No 1x1s: Karen AIACH, CEO

MAG Optics Private Meetings Only Biotechnology Yes Tbd Tbd Tbd

Medgenics, Inc. AMEX:MDGN Presenting & Meetings Biotechnology Yes No No Michael Cola, President & CEO

Medherant Limited Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Nigel Davis, CEO

Merus N.V. NasdaqGM:MRUS Presenting & Meetings Biotechnology Yes Yes No Ton Logtenberg, CEO

Mileutis Private Meetings Only Biotechnology Yes Yes Yes 1x1s: David Javier Iscovich, CEO

Molecular Partners AG SWX:MOLN Presenting & Meetings Biotechnology Yes No No Christian Zahnd, CEO

MolMed S.p.A. BIT:MLM Meetings Only Biotechnology Yes No Yes 1x1s: Riccardo Palmisano, CEO

Nanobiotix SA ENXTPA:NANO Meetings Only Biotechnology Yes No Yes 1x1s: Laurent Levy, CEO

NantKwest, Inc. NasdaqGS:NK Meetings Only Biotechnology Yes Yes Yes 1x1s: David Pyrce, SVP, Innovation, Strategic Initiatives & IR

Neovacs S.A. ENXTPA:ALNEV Meetings Only Biotechnology Yes Yes No 1x1s: Miguel Sieler, CEO

Neurocrine Biosciences, Inc. NasdaqGS:NBIX Presenting & Meetings Biotechnology Yes No No Kevin Gorman, President & CEO

Nordic Nanovector ASA OB:NANO Meetings Only Biotechnology Yes Yes Yes Tbd

Novimmune SA Private Meetings Only Biotechnology No No Yes Tbd

NOXXON Pharma NV Private Meetings Only Biotechnology Yes Yes Yes 1x1s: Aram Mangasarian CEO

Nuevolution AB OM:NUE Meetings Only Biotechnology Yes Yes No 1x1s: Henrik Simonsen, CFO

OSE Immunotherapeutics SA ENXTPA:OSE Meetings Only Biotechnology Yes Yes Yes 1x1s: Dominique Costantini, CEO

OvaScience, Inc. NasdaqGM:OVAS Meetings Only Biotechnology Yes Tbd Tbd Tbd

Oxford BioMedica PLC LSE:OXB Meetings Only Biotechnology Yes No No 1x1s: John Dawson, CEO

Paion AG XTRA:PA8 Meetings Only Biotechnology Yes Yes Yes 1x1s: Wolfgang Soehngen, CEO

PDL BioPharma, Inc. NasdaqGS:PDLI Presenting & Meetings Biotechnology Yes No No John McLaughlin President & CEO

PDL BioPharma, Inc. - B2Bs NasdaqGS:PDLI Meetings Only Biotechnology No No Yes 1x1s: Danny Hart VP, Business Development

Pharmasum Therapeutics Private Meetings Only Biotechnology Yes Tbd Tbd 1x1s: Anders Fugelli, CEO

Pharming Group NV ENXTAM:PHARM Meetings Only Biotechnology Yes Yes Yes 1x1s: Robin Wright, CFO

Pieris Pharmaceuticals, Inc. NasdaqCM:PIRS Meetings Only Biotechnology Yes No No 1x1s: Stephen Yoder, President & CEO

Poxel SA ENXTPA:POXEL Presenting & Meetings Biotechnology Yes Yes Yes Thomas Kuhn, CEO

Probiodrug AG ENXTAM:PBD Meetings Only Biotechnology Yes Yes Yes 1x1s: Hendrik Liebers, CFO

Progenics Pharmaceuticals, Inc. NasdaqGS:PGNX Presenting & Meetings Biotechnology Yes Yes No Mark Baker, CEO

ProMetic Life Sciences Inc. TSX:PLI Meetings Only Biotechnology Yes Yes Yes 1x1s: Bruce Pritchard, COO

ProNAi Therapeutics, Inc. NasdaqGM:DNAI Presenting & Meetings Biotechnology Yes No No Dr. Nick Glover, President & CEO

Protalix Biotherapeutics AMEX:PLX Meetings Only Biotechnology Yes Yes Yes 1x1s: Moshe Manor, President & CEO

PsiOxus Therapeutics Limited Private Meetings Only Biotechnology Yes No No Tbd

Quantum Genomics SA ENXTPA:ALQGC Meetings Only Biotechnology Yes Yes Yes 1x1s: Marc Karako, CFO

Recro Pharma, Inc. NasdaqCM:REPH Presenting & Meetings Biotechnology Yes No No Gerri Henwood, CEO

ReNeuron Group plc AIM:RENE Meetings Only Biotechnology Yes Yes No 1x1s: Olav Hellebo, CEO

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Revance Therapeutics, Inc. NasdaqGM:RVNC Presenting & Meetings Biotechnology Yes No No Lauren Silvernail, CFO & Chief Business Officer

Rigel Pharmaceuticals, Inc. NasdaqGS:RIGL Presenting & Meetings Biotechnology Yes No Yes Raul Rodriguez, President & CEO

Sangamo Biosciences Inc. NasdaqGS:SGMO Presenting & Meetings Biotechnology Yes No No Sandy Macrae, M.B., Ch.B., Ph.D., President & CEO

Santhera Pharmaceuticals Holding

AG SWX:SANN Meetings Only Biotechnology Yes No No 1x1s: Thomas Meier, CEO

Scancell Holdings PLC AIM:SCLP Meetings Only Biotechnology Yes No Yes 1x1s: Richard Goodfellow, CEO

Sensorion SAS ENXTPA:ALSEN Meetings Only Biotechnology Yes Yes Yes 1x1s: Laurent Nguyen, CEO

Snipr Biome Private Meetings Only Biotechnology Yes Yes No Tbd

Sorrento Therapeutics, Inc. NasdaqCM:SRNE Presenting & Meetings Biotechnology Yes Yes No Kevin Herde, EVP & CFO

Spark Therapeutics, Inc. NasdaqGS:ONCE Presenting & Meetings Biotechnology Yes No No Stephen Webster, CFO

Spectrum Pharmaceuticals, Inc. NasdaqGS:SPPI Meetings Only Biotechnology Yes Yes Yes 1x1s: Rajesh Shrotriya, CEO

Stempeutics Research Pvt. Ltd. Private Meetings Only Biotechnology Yes Yes Yes 1x1s: BN Manohar, CEO

Strongbridge Biopharma plc NasdaqGS:SBBP Presenting & Meetings Biotechnology Yes Yes No Matthew Pauls, President & CEO

Swedish Orphan Biovitrum AB OM:SOBI Presenting & Meetings Biotechnology Yes No No Geoffrey McDonough, President & CEO

Symbiomix Therapeutics LLC Private Presenting & Meetings Biotechnology Yes Yes No Robert Jacks, President & CFO

Symphogen A/S Private Presenting & Meetings Biotechnology Yes Yes No Martin Olin, CEO

Synairgen plc AIM:SNG Meetings Only Biotechnology Yes Tbd Tbd Tbd

Synergy Pharmaceuticals, Inc. NasdaqGM:SGYP Presenting & Meetings Biotechnology Yes Yes Yes Gary Jacob, Chairman & CEO

Synpromics Ltd Private Meetings Only Biotechnology Yes Yes Yes 1x1s: David Venables, CEO

TapImmune, Inc. OTCPK:TPIV.D Meetings Only Biotechnology Yes Yes Yes 1x1s: John Bonfiglio, President & COO

Targovax ASA OB:TRVX Meetings Only Biotechnology Yes Yes No 1x1s: Oystein Soug, CFO

TRACON Pharmaceuticals, Inc. NasdaqGM:TCON Presenting & Meetings Biotechnology Yes Yes No Charles Theuer, CEO

TxCell S.A. ENXTPA:TXCL Meetings Only Biotechnology Yes Yes Yes 1x1s: Stephane Boissel, CEO

Valneva SE ENXTPA:VLA Presenting & Meetings Biotechnology Yes Yes No Thomas Lingelbach, President & CEO

Vanda Pharmaceuticals, Inc. NasdaqGM:VNDA Presenting & Meetings Biotechnology Yes No No Mihael Polymeropoulos, President & CEO

Vétoquinol SA ENXTPA:VETO Meetings Only Biotechnology Yes Yes Yes 1x1s: Laurent Thore, Partnerships & Acquisitions Director

Xbrane Biopharma AB OM:XBRANE Meetings Only Biotechnology Yes Yes Yes 1x1s: Martin Amark, CEO

Zealand Pharma A/S CPSE:ZEAL Meetings Only Biotechnology Yes No No 1x1s: Britt Meelby Jensen, President & CEO

ZIOPHARM Oncology, Inc. NasdaqCM:ZIOP Presenting & Meetings Biotechnology Yes No No Laurence Cooper, CEO

AniCura Private Presenting Only Healthcare Services No No No Peter Dahlberg, CEO

Attendo AB OM:ATT Presenting & Meetings Healthcare Services Yes No No Henrik Borelius, President & CEO

BioClinica, Inc. Private Presenting & Meetings Healthcare Services No No Yes Mukhtar Ahmed, President, eHealth Solutions

CRF Health, Inc. Private Presenting Only Healthcare Services No No No Rachael Wyllie, CEO

DVD Participations SAS Private Meetings Only Healthcare Services No No Yes Tbd

Eurofins Scientific SA ENXTPA:ERF Presenting & Meetings Healthcare Services Yes No Yes Gilles Martin, CEO

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Evidensia Djursjukvård AB Private Meetings Only Healthcare Services Yes No No 1x1s: Martin Tiveus, CEO

Fagron NV ENXTBR:FAGR Meetings Only Healthcare Services Yes Tbd Tbd Tbd

General Healthcare Group Limited Private Meetings Only Healthcare Services Yes No Yes Tbd

Georgia Healthcare Group PLC LSE:GHG Presenting & Meetings Healthcare Services Yes Yes Yes Nikoloz Gamkrelidze, CEO

Healthcare Services Group Inc. NasdaqGS:HCSG Presenting & Meetings Healthcare Services Yes No No Matt McKee, VP of Strategy

ICON plc NasdaqGS:ICLR Presenting & Meetings Healthcare Services Yes No No Brendan Brennan, CFO

Mapi Group Private Meetings Only Healthcare Services No No Yes 1x1s: James Karis, CEO

Mater Private Group Private Meetings Only Healthcare Services Yes Tbd Tbd Tbd

MAXIMUS, Inc. NYSE:MMS Presenting & Meetings Healthcare Services Yes No No Rick Nadeau, CFO

MEDIAN Kliniken GmbH & Co. KG Private Presenting Only Healthcare Services No No No André Schmidt, CEO

Medicover Holding S.A. Private Presenting Only Healthcare Services No No No Fredrik Ragmark, CEO

Orpea S.A. ENXTPA:ORP Presenting & Meetings Healthcare Services Yes No No Steve Grobet, Head of IR

Owens & Minor Inc. NYSE:OMI Presenting & Meetings Healthcare Services Yes No No Randy Meier, EVP, CFO & President, International

Patheon Inc. NYSE:PTHN Presenting & Meetings Healthcare Services Yes Yes No Michel Lagarde, President

PT Siloam International Hospitals Tbk JKSE:SILO Presenting & Meetings Healthcare Services Yes Yes No Peter Lembong, Managing Director

Red & Yellow Care Private Meetings Only Healthcare Services Yes Yes Yes 1x1s: Rogier van den Brink, Chief Executive

Rhoen Klinikum AG DB:RHK Meetings Only Healthcare Services Yes Yes No 1x1s: Dr. Kai Gregor Klinger, Head of IR

Spire Healthcare Group Plc LSE:SPI Meetings Only Healthcare Services Yes No No 1x1s: Antony Mannion, Director, Strategy & IR

Surgical Care Affiliates, Inc. NasdaqGS:SCAI Presenting & Meetings Healthcare Services Yes No No Tom De Weerdt, EVP & CFO

Syngene International BSE:539268 Presenting & Meetings Healthcare Services Yes No Yes Jonathan Hunt, CEO

Walgreens Boots Alliance, Inc. NasdaqGS:WBA Presenting Only Healthcare Services No No No George Fairweather, EVP & Global CFO

BioMerieux S.A. ENXTPA:BIM Presenting & Meetings Life Sciences Yes No No Sylvain Morgeau, IR

Bio-Techne Corp. NasdaqGS:TECH Presenting & Meetings Life Sciences Yes No No Chuck Kummeth, President & CEO

Centogene AG Private Meetings Only Life Sciences Yes Yes Yes 1x1s: Fanny Cheung, Director Corp Fin & IR

Clyde Biosciences Ltd. Private Meetings Only Life Sciences Yes No Yes 1x1s: Chris Wardhaugh, COO

Curetis N.V. ENXTAM:CURE Meetings Only Life Sciences Yes Yes Yes 1x1s: Oliver Schacht, CEO

Discuva Limited Private Meetings Only Life Sciences Yes Yes Yes 1x1s: David Williams, CEO

Evotec AG XTRA:EVT Presenting & Meetings Life Sciences Yes Yes Yes Enno Spillner, CFO

Exorao Life Science Private Meetings Only Life Sciences No Yes Yes Tbd

GreenBone Ortho srl Private Meetings Only Life Sciences Yes Tbd Tbd Tbd

hVIVO plc AIM:HVO Meetings Only Life Sciences Yes Yes No 1x1s: Kym Denny, CEO

IDT Biologika GmbH Private Meetings Only Life Sciences Yes Yes Yes Tbd

MISSION Therapeutics Ltd. Private Meetings Only Life Sciences Yes No No 1x1s: Anker Lundemose, CEO

PureTech Health plc LSE:PRTC Presenting & Meetings Life Sciences Yes Yes Yes Daphne Zohar, Founder & CEO

Quintiles IMS Holdings, Inc. NYSE:Q Meetings Only Life Sciences Yes Tbd Tbd Tbd

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Selvita S.A. WSE:SLV Meetings Only Life Sciences Yes No Yes 1x1s: Pawel Przewiezlikowski, CEO

Stratec Biomedical AG DB:SBS Meetings Only Life Sciences Yes No No 1x1s: Dr. Claus Vielsack, Member of the Board

Tecan Group AG SWX:TECN Presenting & Meetings Life Sciences Yes No No David Martyr, CEO

Align Technology Inc. NasdaqGS:ALGN Presenting & Meetings Medtech Yes No No Simon Beard, VP, Managing Director of EMEA

Ambu A/S CPSE:AMBU B Meetings Only Medtech Yes Tbd Tbd Tbd

ANGLE Plc AIM:AGL Meetings Only Medtech Yes No Yes 1x1s: Andrew Newland, Chief Executive

Cambridge Medical Robotics Limited Private Meetings Only Medtech Yes Tbd Tbd Tbd

Cellnovo Limited ENXTPA:CLNV Meetings Only Medtech Yes Yes Yes 1x1s: Sophie Baratte, CEO

Coloplast A/S CPSE:COLO B Presenting & Meetings Medtech Yes No No Anders Lonning-Skovgaard, CFO

DENTSPLY SIRONA Inc. NasdaqGS:XRAY Meetings Only Medtech Yes No No 1x1s: Derek Leckow, VP, IR

EnXray Limited Private Meetings Only Medtech Yes Yes Yes 1x1s: Edward Cappabianca, CEO

GN Store Nord A/S CPSE:GN Presenting & Meetings Medtech Yes No No Peter Justesen, VP, IR & Treasury

Haemonetics Corp NYSE:HAE Meetings Only Medtech Yes No No 1x1s: Gerry Gould, VP, IR

Ion Beam Applications (PPM) ENXTBR:IBAB Presenting & Meetings Medtech Yes No Yes Jean-Marc Bothy, Chief Strategy Officer

LivaNova PLC LSE:LIVN Presenting & Meetings Medtech Yes No No Andre-Michel Ballester, CEO

Mainstay Medical International plc ENXTPA:MSTY Meetings Only Medtech Yes Yes No 1x1s: Hugh Kavanagh, CFO

Merit Medical Systems, Inc. NasdaqGS:MMSI Presenting & Meetings Medtech Yes No No Bernard Birkett, CFO

Nexstim Plc HLSE:NXTMH Meetings Only Medtech Yes Yes No 1x1s: Martin Jamieson, Chairman & CEO

OptiNose US Inc. Private Meetings Only Medtech Yes No No 1x1s: Peter Miller, CEO

Oxford Immunotec Global PLC NasdaqGM:OXFD Presenting & Meetings Medtech Yes No No Peter Wrighton-Smith, CEO

Pixium Vision SA ENXTPA:PIX Presenting & Meetings Medtech Yes Yes No Khalid Ishaque, CEO

Presbia PLC NasdaqGM:LENS Meetings Only Medtech Yes Yes Yes 1x1s: Todd Cooper, CEO

Quanta Dialysis Technologies Ltd Private Meetings Only Medtech Yes Yes No 1x1s: John Milad, CEO

Quotient Limited NasdaqGM:QTNT Presenting & Meetings Medtech Yes No No Paul Cowan, Chairman & CEO

ReWalk Robotics Ltd. NasdaqGM:RWLK Meetings Only Medtech Yes No No 1x1s: Kevin Hershberger, CFO

Smith & Nephew plc LSE:SN. Presenting & Meetings Medtech Yes No No Julie Brown, CFO

Syneron Medical Ltd. NasdaqGS:ELOS Meetings Only Medtech Yes No No 1x1s: Hugo Goldman, CFO

Tissue Regenix Group Plc AIM:TRX Presenting & Meetings Medtech Yes Yes Yes Antony Odell, CEO

Varian Medical Systems Inc. NYSE:VAR Presenting & Meetings Medtech Yes No No Neil Madle, Director, IR & Corp Communications

William Demant Holding A/S CPSE:WDH Presenting & Meetings Medtech Yes No No René Schneider, CFO

Wright Medical Group N.V. NasdaqGS:WMGI Presenting & Meetings Medtech Yes No No Julie Tracy, SVP & Chief Communications Officer

AbbVie Inc. NYSE:ABBV Presenting & Meetings Pharmaceuticals Yes No No Bill Chase, EVP & CFO

AC Immune SA Private Presenting & Meetings Pharmaceuticals Yes Tbd Tbd Andrea Pfeifer, CEO

Accord Healthcare Ltd Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: James Burt, EVP, Europe & MENA

AcelRx Pharmaceuticals, Inc. NasdaqGM:ACRX Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Timothy Morris, CFO & Head of Business Development

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Acino International AG Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Kalle Känd, CEO, Acino Group

Adapt Pharma Private Meetings Only Pharmaceuticals No No Yes Tbd

Adare Pharmaceuticals, Inc. Private Meetings Only Pharmaceuticals Yes Yes No 1x1s: Steve Tuleja, Sr Director

Advanced Accelerator Applications NasdaqGS:AAAP Presenting & Meetings Pharmaceuticals Yes Yes No Heinz Mausli, CFO

Aenova Holding GmbH Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Aerie Pharmaceuticals, Inc. NasdaqGM:AERI Presenting & Meetings Pharmaceuticals Yes Yes No Rich Rubino, CFO

Akari Therapeutics Plc NasdaqCM:AKTX Meetings Only Pharmaceuticals Yes Yes No 1x1s: Gur Roshwalb, CEO

Alcobra Ltd. NasdaqGM:ADHD Presenting & Meetings Pharmaceuticals Yes No No Yaron Daniely, CEO

ALK-Abello CPSE:ALK B Presenting & Meetings Pharmaceuticals Yes No Yes Flemming Pedersen, CFO & EVP

Allecra Therapeutics GmbH Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Nicholas Benedict, CEO

Allergan, Inc. NYSE:AGN Meetings Only Pharmaceuticals No No Yes

1x1s: Anish Mehta, Head, International Business

Development

Alliance Pharma plc AIM:APH Presenting & Meetings Pharmaceuticals Yes No Yes John Dawson, CEO

Allied Minds plc LSE:ALM Presenting & Meetings Pharmaceuticals Yes Yes No Christopher Silva, CEO

Almirall, S.A. CATS:ALM Meetings Only Pharmaceuticals Yes Yes Yes

1x1s: Marta Garcia Torres, Sr Manager, M&A Corp

Development

Alter Pharma Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Alvogen, Inc. Private Presenting & Meetings Pharmaceuticals Yes No Yes Robert Wessman, CEO & Chairman

Alvotech Private Presenting & Meetings Pharmaceuticals Yes Yes Yes Eef Schimmelpennink, CEO

AMAG Pharmaceuticals, Inc. NasdaqGS:AMAG Presenting & Meetings Pharmaceuticals Yes No No William Heiden, CEO

Amneal Pharmaceuticals Private Meetings Only Pharmaceuticals No Tbd Tbd Tbd

Amryt Pharma plc AIM:AMYT Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Rory Nealon, CFO

Antares Pharma Inc. NasdaqCM:ATRS Presenting & Meetings Pharmaceuticals Yes No No Bob Apple, President & CEO

Aquinox Pharmaceuticals Inc. NasdaqGM:AQXP Meetings Only Pharmaceuticals Yes Yes No 1x1s: David Main, President & CEO

Aralez Pharmaceuticals Inc. TSX:ARZ Presenting & Meetings Pharmaceuticals Yes Yes No Adrian Adams, CEO

Ascendis Health Limited JSE:ASC Presenting & Meetings Pharmaceuticals Yes No Yes Karsten Wellner, CEO

BioDelivery Sciences International NasdaqCM:BDSI Presenting & Meetings Pharmaceuticals Yes Yes No Mark A. Sirgo, President & CEO

BioNTech AG Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Sean Marett, COO

Bristol-Myers Squibb Company NYSE:BMY Meetings Only Pharmaceuticals No Tbd Tbd Tbd

BTG Plc LSE:BTG Presenting & Meetings Pharmaceuticals Yes No No Louise Makin, CEO

Cassiopea Spa SWX:SKIN Presenting & Meetings Pharmaceuticals Yes No No Diana Harbort, CEO

Cempra, Inc. NasdaqGS:CEMP Presenting & Meetings Pharmaceuticals Yes No No Prabhavathi Fernandes, President & CEO

Chemo Iberica, S.A. Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Ignacio Ponce Gutierrez, CFO & Corp Development

China Medical System Holdings SEHK:867 Presenting & Meetings Pharmaceuticals Yes Yes Yes Tbd

Claris Lifesciences Limited BSE:533288 Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Clinigen Group Plc AIM:CLIN Meetings Only Pharmaceuticals Yes No Yes 1x1s: Shaun Chilton, CEO

Cocrystal Pharma, Inc. TCBB:COCP Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Collegium Pharmaceutical, Inc. NasdaqGS:COLL Presenting & Meetings Pharmaceuticals Yes No No Michael Heffernan, President & CEO

Concordia Healthcare Corp. TSX:CXR Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Consilient Health Ltd. Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Ahmed Al-Derzi, CEO

Cosmo Pharmaceuticals NV SIX:COPN Presenting & Meetings Pharmaceuticals Yes No No Della Cha Alessandro, CEO

Cymabay Therapeutics, Inc. NasdaqCM:CBAY Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Harold Van Wart, President & CEO

Doc Generici S.R.L. Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Stefano Cortesi, CFO

Dong-A Socio Holdings Co.,Ltd KOSE:A170900 Meetings Only Pharmaceuticals Yes Yes No 1x1s: Dong Hoon Lee, EVP

Egis Pharmaceuticals PLC Private Meetings Only Pharmaceuticals No Yes Yes 1x1s: Poroszlai Csaba, CFO

Eiger BioPharmaceuticals, Inc. NasdaqGM:EIGR Presenting & Meetings Pharmaceuticals Yes No No David Cory, President & CEO

Ethypharm SA Private Meetings Only Pharmaceuticals No No Yes 1x1s: Hugues Lecat, CEO

Evgen Pharma plc AIM:EVG Meetings Only Pharmaceuticals Yes No No 1x1s: Stephen Franklin, CEO

Faes Farma, S.A. CATS:FAE Meetings Only Pharmaceuticals No No Yes 1x1s: Paco Quintanilla, Managing Director

Farmak Joint Stock Company Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Faron Pharmaceuticals Oy AIM:FARN Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Markku Jalkanen, CEO

Ferring Pharmaceuticals Private Meetings Only Pharmaceuticals No No Yes Tbd

Flamel Technologies SA NasdaqGM:FLML Presenting & Meetings Pharmaceuticals Yes No Yes Mike Anderson, CEO

Foamix Pharmaceuticals Ltd. NasdaqGM:FOMX Presenting & Meetings Pharmaceuticals Yes Yes Yes Dov Tamarkin, CEO

Galenica Ltd. SWX:GALN Presenting & Meetings Pharmaceuticals Yes No No Colin Bond, CFO, Vifor Pharma

GlaxoSmithKline plc LSE:GSK Meetings Only Pharmaceuticals Yes No No 1x1s: Gary Davies, Director, IR

Glenmark Pharmaceuticals Ltd. BSE:532296 Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Grupo J Uriach S.L. Private Meetings Only Pharmaceuticals Yes Yes Yes Tbd

H. Lundbeck A/S CPSE:LUN Presenting & Meetings Pharmaceuticals Yes No No Palle H. Olesen, VP, IR

Harbin Gloria Pharmaceuticals Co. SZSE:002437 Meetings Only Pharmaceuticals No No Yes 1x1s: Monica Jiang, Investment Director

Hikma Pharmaceuticals plc LSE:HIK Meetings Only Pharmaceuticals Yes Yes No 1x1s: Khalid Nabilsi, CFO

Hikma Pharmaceuticals plc - B2Bs LSE:HIK Meetings Only Pharmaceuticals No No Yes Tbd

Horizon Pharma plc NasdaqGS:HZNP Presenting & Meetings Pharmaceuticals Yes No No Paul Hoelscher, CFO

HRA Pharma, SA Private Meetings Only Pharmaceuticals Yes No Yes 1x1s: François Vuillet, CEO

Hypermarcas SA BOVESPA:HYPE3 Presenting & Meetings Pharmaceuticals Yes No Yes Martim Mattos, CFO

Indivior PLC LSE:INDV Meetings Only Pharmaceuticals Yes No No 1x1s: Tom Corran, IR Director

infirst Healthcare Ltd. Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Intas Pharmaceuticals Ltd. Private Meetings Only Pharmaceuticals No No Yes Tbd

Integrated Pharma Solutions Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Ahmed Yacout, CEO

Ipsen S.A. ENXTPA:IPN Presenting & Meetings Pharmaceuticals Yes No No Aymeric Le Chatelier, CFO

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Jazz Pharmaceuticals NasdaqGS:JAZZ Presenting & Meetings Pharmaceuticals Yes No No Iain McGill, SVP

Karus Therapeutics Limited Private Meetings Only Pharmaceuticals Yes No Yes 1x1s: Simon Kerry, CEO

Labatec Pharma Sa Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Sofia Ysewyn, Head of M&A

Laboratorio Reig Jofre SA CATS:RJF Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Ignasi Biosca, CEO

Laboratorios del Dr. Esteve, S.A. Private Meetings Only Pharmaceuticals No No Yes 1x1s: Jordi Esteve, Sr Head of Pharma Expansion

Laboratorios Farmaceuticos ROVI CATS:ROVI Presenting & Meetings Pharmaceuticals Yes No Yes Juan López-Belmonte, CEO

Lannett Company, Inc. NYSE:LCI Presenting & Meetings Pharmaceuticals Yes No No Arthur Bedrosian, CEO

Lee's Pharmaceutical Holdings Ltd. SEHK:950 Meetings Only Pharmaceuticals Yes No Yes 1x1s: Benjamin Li, CEO

Mallinckrodt plc NYSE:MNK Presenting & Meetings Pharmaceuticals Yes No No Cole Lannum, SVP, Investor Strategy & IRO

Mapi Pharma Ltd. Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Ehud Marom, CEO

Marathon Pharmaceuticals, LLC Private Meetings Only Pharmaceuticals No No Yes 1x1s: Andrew Serafin, VP, Business Development

Martindale Pharma Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Michael Harris, CEO

Medichem, S.A. Private Presenting & Meetings Pharmaceuticals No No Yes Elisabeth Stampa, CEO

Menarini Group Private Meetings Only Pharmaceuticals No No Yes 1x1s: Giammario Piras, Corporate Licensing Director

Merck KGaA DB:MRK Meetings Only Pharmaceuticals Yes No No Tbd

Merus Labs International Inc. TSX:MSL Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

MiNa Therapeutics Ltd Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Mithra Pharmaceuticals SA ENXTBR:MITRA Meetings Only Pharmaceuticals Yes No No 1x1s: Steven Peters, CFO

Mitsubishi Tanabe Pharma Corp. TSE:4508 Presenting & Meetings Pharmaceuticals Yes Yes Yes Soren Demin, Sr Manager

Moberg Pharma AB OM:MOB Meetings Only Pharmaceuticals Yes No Yes 1x1s: Peter Wolpert, CEO

Molteni Farmaceutici Private Meetings Only Pharmaceuticals No No Yes Tbd

Motif Bio Plc AIM:MTFB Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Graham Lumsden, CEO

Munir Sukhtian Pharmaceuticals Private Meetings Only Pharmaceuticals Yes Tbd Tbd 1x1s: Faisal Sukhtian, Director

Mylan, Inc. NasdaqGS:MYL Meetings Only Pharmaceuticals No Yes Yes 1x1s: Andrew Cuneo, Head of Global Business Development

Nektar Therapeutics NasdaqGS:NKTR Presenting & Meetings Pharmaceuticals Yes No No Tbd

NeuroDerm, Ltd. NasdaqGM:NDRM Presenting & Meetings Pharmaceuticals Yes No No Oded Lieberman, CEO

Newron Pharmaceuticals S.p.A. SWX:NWRN Presenting & Meetings Pharmaceuticals Yes No No Tbd

NextPharma GmbH Private Meetings Only Pharmaceuticals No Yes Yes 1x1s: Peter Burema, CEO

Noden Pharma DAC Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Norgine BV Private Meetings Only Pharmaceuticals No Yes Yes 1x1s: Peter Stein CEO

Norgine Ventures Private Meetings Only Pharmaceuticals No Yes Yes 1x1s: Julien Michaux Managing Director, Norgine Ventures

Novartis AG SWX:NOVN Presenting & Meetings Pharmaceuticals Yes No No Tobias Hestler, CFO, Sandoz

Noventia Pharma Private Meetings Only Pharmaceuticals Yes Yes No 1x1s: Massimo Radelli, Chairman, President & CEO

Novo Nordisk A/S CPSE:NOVO B Presenting & Meetings Pharmaceuticals Yes No No Melanie Raouzeos, IR Manager

NuCana BioMed Limited Private Presenting Only Pharmaceuticals No No No Hugh Griffith, CEO

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

Oculis Pharma Private Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Pall Ragnar Johannesson, CEO

Oramed Pharmaceuticals Inc. NasdaqCM:ORMP Meetings Only Pharmaceuticals Yes No Yes 1x1s: Josh Hexter, COO

Orexo AB OM:ORX Meetings Only Pharmaceuticals Yes No No 1x1s: Nikolaj Sørensen, CEO & President

Orion Oyj HLSE:ORNBV Presenting & Meetings Pharmaceuticals Yes Yes No Jari Karlson, CFO

Pacira Pharmaceuticals Inc. NasdaqGS:PCRX Presenting & Meetings Pharmaceuticals Yes No No Dave Stack, CEO & Chairman

Peptinnovate Limited Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Pharma Two B Ltd. Private Meetings Only Pharmaceuticals Yes Yes Yes Tbd

Pharnext S.A. ENXTPA:ALPHA Meetings Only Pharmaceuticals Yes No No 1x1s: Daniel Cohen, CEO

Pierre Fabre Medicament Private Presenting & Meetings Pharmaceuticals Yes Yes Yes Frederic Duchesne CEO Pharmaceuticals Division

Provectus Biopharmaceuticals, Inc. AMEX:PVCT Meetings Only Pharmaceuticals Yes Yes No 1x1s: Peter Culpepper, CEO (Interim) & COO

Recipharm AB OM:RECI B Presenting & Meetings Pharmaceuticals Yes No Yes Thomas Eldered, CEO

Recordati SpA BIT:REC Presenting & Meetings Pharmaceuticals Yes No No Fritz Squindo, CFO

RedHill Biopharma Ltd. TASE:RDHL Presenting & Meetings Pharmaceuticals Yes Yes No Dror Ben-Asher, CEO

Roche Holding Ltd SWX:ROG Presenting & Meetings Pharmaceuticals Yes Yes No Stefan Frings, Medical Affairs Director Roche Germany

Roche Holding Ltd - B2Bs SWX:ROG Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

R-Pharm, CJSC Private Presenting & Meetings Pharmaceuticals Yes Yes Yes Vasily Ignatiev, CEO

Sandoz International GmbH Private Meetings Only Pharmaceuticals No Yes Yes 1x1s: Ralf Schmidt, Head of Global M&A

SEEK Private Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Shanghai Fosun Pharmaceutical SHSE:600196 Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Gino Li, Deputy GM of IR & Capital Deployment

Shanghai Fosun Pharma - B2Bs SHSE:600196 Meetings Only Pharmaceuticals Yes Yes Yes 1x1s: Sean Wu Sr Investment Director

Shire plc LSE:SHP Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Sinclair Pharma Plc AIM:SPH Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

ST Pharm Co. Ltd. KOSDAQ:A237690 Meetings Only Pharmaceuticals Yes Tbd Tbd Tbd

Stada-Arzneimittel AG DB:SAZ Meetings Only Pharmaceuticals No No Yes Tbd

Sucampo Pharmaceuticals, Inc. NasdaqGM:SCMP Presenting & Meetings Pharmaceuticals Yes Yes Yes Peter Greenleaf, Chairman & CEO

Supernus Pharmaceuticals, Inc. NasdaqGM:SUPN Presenting & Meetings Pharmaceuticals Yes No No Jack Khattar, CEO

Suven Life Sciences Limited BSE:530239 Presenting & Meetings Pharmaceuticals Yes Yes Yes Venkat Jasti, Chairman & CEO

Takeda Pharmaceutical Co. Ltd. TSE:4502 Meetings Only Pharmaceuticals Yes No No 1x1s: Rudolf van Houten, Group Financial Controller

TherapeuticsMD, Inc. AMEX:TXMD Presenting & Meetings Pharmaceuticals Yes Yes No Robert Finizio, CEO

Tillotts Pharma AG Switzerland Private Meetings Only Pharmaceuticals No No Yes 1x1s: Dirk Reckert, CBDO

UCB SA ENXTBR:UCB Meetings Only Pharmaceuticals Yes No No 1x1s: Isabelle Ghellynck, Associate Director, IR

Union Quimico Farmacéutica, S.A. Privatep Meetings Only Pharmaceuticals Yes Yes Yes Tbd

vasopharm GmbH Private Meetings Only Pharmaceuticals Yes No Yes 1x1s: Andrew Clark, Chairman

Vectura Group Plc LSE:VEC Presenting & Meetings Pharmaceuticals Yes No No James Ward-Lilley, CEO

Verona Pharma plc AIM:VR Meetings Only Pharmaceuticals Yes No Yes Tbd

PARTICIPATING COMPANIES Jefferies 2016 London Healthcare Conference

Presenting companies are subject to change.

Company Name Ticker Type Sector Investor Meetings

Sponsor Meetings

B2B Meetings Speaker/Attendee

WAVE Life Sciences Pte. Ltd. NasdaqGM:WVE Presenting & Meetings Pharmaceuticals Yes Yes Yes Paul Bolno, CEO

Zynerba Pharmaceuticals, Inc. NasdaqGM:ZYNE Presenting & Meetings Pharmaceuticals Yes No No Armando Anido, Chairman & CEO

Assura Plc LSE:AGR Meetings Only REITs Yes Tbd Tbd Tbd

Medical Properties Trust NYSE:MPW Presenting & Meetings REITs Yes Yes Yes Ed Aldag, Chairman, President & CEO