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Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe Adriana Maggi JPND Vice-Chair Rome Dec 15, 2017

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Page 1: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Joint Programming in

Neurodegenerative Disease Research (JPND)

Coordinating approaches to research across the globe

Adriana Maggi

JPND Vice-Chair

Rome Dec 15, 2017

Page 2: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

We cannot tackle neurodegenerative

diseases by acting as single countries

Albania

Austria

Belgium

Canada

Croatia

Czech Republic

Denmark

Finland

France

Germany

Greece

Hungary

Ireland

Israel

Italy

Luxembourg

Netherlands

Norway

Poland

PortugalRomania

Slovakia

Slovenia

Spain

Sweden

Switzerland

Turkey

United Kingdom

JPND is the largest global ND research initiative

led by EU countries, with 30 participating

EU member states

Associated countries

Third countries

Increasing coordination of national

research programmes to improve

impact and effectiveness

A European Research Area and beyond

Australia

Bulgaria

Page 3: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Scientific

• Animal models

• Biobanks

• Cohorts/registries

• Disease pathology

Social

• Health care delivery

• Home automation

• Health economics

• Ethics

Medical

• Early diagnosis

• Prevention

• Clinical trials

Focus on

Three Domains

Scope of the initiative

Page 4: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

JPND brings together

• Researchers (Basic, Clinical, Healthcare/Social)

• National Funding Bodies

• National Research Strategies and Investments

• Industry

Page 5: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Referenti JPND - Italia

Fabrizio Tagliavini Ministero Salute

Aldo Covello MIUR

Valeria Cardia MIUR

Adriana Maggi Vice-chair

Page 6: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Implementing transnational and

additional joint calls

Total investment €128 M

Joint Transnational Calls:

o Between 20 and 175

proposals

o Between 122 and 892

teams

o 95 projects supported +

ongoing €23 million call

o including 24 projects in

the Center of Excellence

Network program

Page 7: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

JPND JTC number of proposals

14 2252

35

92

22

175

0

20

40

60

80

100

120

140

160

180Success rate from 30% to 12%

Page 8: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Come ha lavorato fino ad ora JPND

Total investment €128 M

Joint Transnational Calls:

Between 20 and 175 proposals

Between 122 and 892 teams

95 projects supported + ongoing € 23 million call

including 24 projects in the Center of Excellence Network

program

Portals:

Current EU research projects on ND

on human cohorts

on animal models in Parkinson

Page 9: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

2018 JPND call

• 2018 Multinational research projects

on health and social care for

Neurodegenerative Diseases

• Deadline March 2018

Page 10: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Attività future Call 2019 (risposta entro il 22/12)

• Personalized Diagnosis, prevention and care to promote researh aimed at changing the

trajectory of ND through the development of personalized approaches: predictive diagnostic tools, preventive

approaches and interventions, clinical and patient-oriented translational research

• Challenges of Brain Imaging in fundamental research and clinical studiesharmonization and establishment of guidelines for future research and use of brain imaging in ND

• Discovery and validation of biomarkers for diagnosis and clinical studiesdiscovery and validation of novel biomarkers for clinical usage: the call may :the call may equally target clinical and

basic research and may even support existing cohorts as well as ethics of preclinical screening

• Genetic and environmental risk factors discovery and modelling of genetic and environmental

risk factors which pronounces the pathogenetic relevance. Research dominated by fundamental research, might as

well be open to cohorts support

• Model systems: from cells to animals cell and animal models are fundamental for clinical and

translational researchand represent an excellent entering point for collaborative research projects of academics

and industry: the call will focus on the translation from cell to animals and thus address fundamental research

Page 11: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Keep up to date

• Visit the JPND website:

• http://www.jpnd.eu

• Sign up to the JPND News Feeds

• E-mail us: [email protected]

@JPNDEurope

Page 12: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Influenza sui contenuti futuro PQ

Siamo stati consultati, tuttavia sono perplessa in quanto non ci

sono state call sulle malattie neurodegenerative /brain nell’ambito

di Horizon 2020

Page 13: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Come ha lavorato fino ad ora JPND

Total investment €128 M

Joint Transnational Calls:

Between 20 and 175 proposals

Between 122 and 892 teams

95 projects supported + ongoing €23 million call

including 24 projects in the Center of Excellence Network

program

Portals:

on human cohorts

on animal models in Parkinson

Page 14: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Scientific

• Animal models

• Biobanks

• Cohorts/registries

• Disease pathology

Social

• Health care delivery

• Home automation

• Health economics

• Ethics

Medical

• Early diagnosis

• Prevention

• Clinical trials

Aree di Focus JPND

Disease areas

Alzheimer's disease and other dementiasHuntington's diseaseMotor Neurone DiseasesParkinson's disease and PD-related disordersPrion diseaseSpinal muscular atrophy (SMA)Spinocerebellar ataxia (SCA)

Focus on Three Domains

Page 15: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Attività future

• 2018 Multinational research projects

on health and social care for

Neurodegenerative Diseases

• Deadline March 2018

Page 16: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Attività future Call 2019 (risposta entro il 22/12)

• Personalized Diagnosis, prevention and care to promote researh aimed at changing the

trajectory of ND through the development of personalized approaches: predictive diagnostic tools, preventive

approaches and interventions, clinical and patient-oriented translational research

• Challenges of Brain Imaging in fundamental research and clinical studiesharmonization and establishment of guidelines for future research and use of brain imaging in ND

• Discovery and validation of biomarkers for diagnosis and clinical studiesdiscovery and validation of novel biomarkers for clinical usage: the call may :the call may equally target clinical and

basic research and may even support existing cohorts as well as ethics of preclinical screening

• Genetic and environmental risk factors discovery and modelling of genetic and environmental

risk factors which pronounces the pathogenetic relevance. Research dominated by fundamental research, might as

well be open to cohorts support

• Model systems: from cells to animals cell and animal models are fundamental for clinical and

translational researchand represent an excellent entering point for collaborative research projects of academics

and industry: the call will focus on the translation from cell to animals and thus address fundamental research

Page 17: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Come i singoli gruppi possono partecipare

Ricercatori di base e clinici tutti potranno essere finanziati

Entrare in reti internazionali di ricerca

Page 18: Joint Programming in Neurodegenerative Disease Research … · Joint Programming in Neurodegenerative Disease Research (JPND) Coordinating approaches to research across the globe

Referenti JPND - Italia

Fabrizio Tagliavini Ministero Salute

Aldo Covello MIUR

Valeria Cardia MIUR

Adriana Maggi Vice-chair