WHO side meeting on HIV self-testingJuly 18, 2015

JIPIME study: the use of self-testing to promote

partner testing

Harsha ThirumurthyUNC Chapel Hill

Kawango AgotIRDO

Study team and fundingCo-Principal Investigators

Harsha Thirumurthy1, Kawango Agot2

Co-InvestigatorsEunice Omanga2, Suzanne Maman1, Sue Mavedzenge3

FundingInternational Initiative for Impact Evaluation, Bill and Melinda Gates Foundation

1 University of North Carolina at Chapel Hill; 2 Impact Research & Development Organization; 3 RTI International

Background HIV testing among male partners of

pregnant women may decrease HIV transmission to women and promote PMTCT uptake

Male partner testing is low in many countries, however <20% of male partners undergo clinic-based HCT in

most low-resource settings, even following adaptations to the ANC clinics to encourage male attendance

Barriers to male testing in ANC include inadequate infrastructure within the ANC clinics and cultural norms that view ANC clinics as limited to women

Promoting partner testing with HIVST

HIVST has high acceptability in Kenya Pilot study in Kisumu shows feasibility of

intervention that relies on secondary distribution of self-test kits Women who receive multiple self-test kits were able

to give self-test kits to their male partners and encourage them to use it (MOAC0302LB, July 20)

Research needed to establish whether HIVST is effective at increasing partner testing among pregnant and postpartum women

Jipime (test yourself): study design Ongoing randomized trial in Kisumu, Kenya

Objective: determine whether provision of 2 self-tests to pregnant and postpartum women is more effective at promoting partner testing than standard of care (partner invitation for HIV testing)

Eligibility: adult women in stable partnerships who attend ANC or PPC at 3 health facilities in or near Kisumu

Target enrollment of 600 participants (randomized in 1:1 ratio)Intervention

groupWomen given two HIV self-tests and

encouraged to initiate HIV testing

with primary partner

Control groupWomen given a

referral letter that encourages their

primary partner to seek HTC

Study progress and outcomes Study progress

Enrollment began in June 2015 228 participants enrolled and randomized so far 1-month follow-up interviews under way

Primary outcome Uptake of HIV testing by women’s partner within 3 months of enrollment Measurement: Self-reported use of self-testing in intervention group;

self-reported uptake of HTC in control group Secondary outcomes

Discussions about HIV testing Partner testing vs. couples testing Actions taken after HIV testing (confirmatory testing, linkage to care) Adverse reactions or gender-based violence

Results expected later this year