jss academy of higher education & research, mysore (deemed

JSS Academy of Higher Education & Research, Mysore

(Deemed to be University)

(Accredited ‘A+’ Grade by NAAC)

JSS COLLEGE OF PHARMACY, ROCKLANDS, OOTY

(ISO 9001:2015 Certified)

Academic Calendar

(Academic Year: 2020-2021)

Course:III. PHARM.D.

2

CONTENTS Page No.

Excerpt from JSS Academy of Higher Education & Research regulations 3

Internal Assessment Marks 3

Conditions under which candidates are permitted to appear for university

examination

4

Declaration of class 5

Award of Ranks 5

Award of degree 6

Duration for completion of the course of study 6

Revaluation /Retotaling of answer papers 6

Withdrawal from the Program 6

Dismissal 6

Readmission after break of study 6

Syllabus of III Pharm.D 7-22

Details of Subject Teachers 23

Academic Plan 24-47

Time Table 48

Student Support Services 49

Committees for various activities 50-57

Responsibilities of each committee 58-62

Grievance Redressal Committee 63

Anti – Ragging Committee 63-65

3

EXCERPT FROM JSS ACADEMY OF HIGHER EDUCATION & RESEARCH

REGULATIONS

Medium of Instruction and Examinations

Medium of Instruction and Examination shall be in English.

Working days in the academic year 2020-21

Academic year 2020-21 shall consist of not less than 215 working days.

Attendance and Progress:

A candidate is required to put in at least 80% attendance in theory and practical subjects separately.

The candidate shall complete the prescribed course satisfactorily to be eligible to appear for the

respective examinations.

Course of study

The course of study for III Year Pharm D shall include the objects as given in the Table.

S.No. Name ofSubject No. of hoursof

Theory

No. of hoursof

Practical

No. of hoursof

Tutorial (1) (2) (3) (4) (5)

3.1 Pharmacology-II 3 3 1

3.2 Pharmaceutical Analysis 3 3 1

3.3 Pharmacotherapeutics-II 3 3 1

3.4 Pharmaceutical Jurisprudence 2 - -

3.5 Medicinal Chemistry 3 3 1

3.6 Pharmaceutical Formulations 2 3 1

Total hours 16 15 5 = 36

Academic Work

A regular record of attendance both in Theory and Practical shall be maintained by the teaching staff

of respective subjects.

Internal Assessment Marks

Theory: Three sessional examinations evenly spread during the academic year shall be conducted.

The average marks of the best two examinations shall be computed out of a maximum of 30 marks

and shall constitute the sessional award in theory. Provided further the college may conduct one

special theory sessional examination towards the end of the academic session for those who might

have missed any one of the regular sessional examination on genuine grounds. Each theory sessional

examination shall be of 1.5 hours’ duration.

Practical: Students are expected to perform the experiment listed in the respective syllabus. Marks

shall be awarded out of a maximum of 10 to each of the practical exercise and an average of those

shall be computed out of maximum of 10 marks. In addition, three practical examinations evenly

spread during each academic year shall be conducted. The average marks of the best of two practical

examinations shall be computed out of a maximum of 20 marks. A total of 30 marks shall constitute

4

the sessional award in practical. While awarding the sessional marks for practical experiments, the

following considerations should be taken into account.

1. Preparation of the candidate.

2. Manipulative skills.

3. Results of the experiment.

4. Knowledge of the experiment

5. Viva voce pertaining to the experiments only.

Each Practical sessional examination shall be of 3 hours’ duration.

Conditions under which candidates are permitted to appear for university examination

The candidates are required to score a minimum of 50% marks in each of the subjects (Theory and

practical separately) in the sessional examination to be eligible to appear for university examination in

the respective subject.

University Examinations

(1) Every year there shall be an examination to examine the students.

(2) Each examination will be held twice every year. The first examination in a year shall be the annual

examination and the second examination shall be supplementary examination.

(3) The examinations shall be of written and practical (including oral nature) carrying maximum

marks for each part of a subject as indicated in Table.

(4) All the theory and practical examinations of the university shall be of 3 hours and 4 hours’

duration respectively.

S.No

.

NameofSubject MaximummarksforTheory Maximummarksfor Practical’s

Examinatio

n

Sessiona

l

Tota

l

Examinatio

n

Sessiona

l

Total

3.1 Pharmacology-II 70 30 100 70 30 100

3.2 PharmaceuticalAnalysis 70 30 100 70 30 100

3.3 Pharmacotherapeutics-II 70 30 100 70 30 100

3.4 Pharmaceutical

Jurisprudence

70 30 100 - - -

3.5 MedicinalChemistry 70 30 100 70 30 100

3.6 PharmaceuticalFormulatio

ns

70 30 100 70 30 100

600 500=110

0

Question Pattern

Long Essay 2 out of 3 = 2 x 10 = 20 marks

Short Essay 6 out of 9 = 6 x 5 = 30 marks

MCQ’s 20 = 1 x 20 = 20 marks

-------------------

Total 70 marks

----------------

Criteria for pass

5

a) Candidates who have secured a minimum of 50% marks in the Theory (including Sessionals) and

Practical (including Sessionals) separately in any subject or subjects shall be declared to have passed

in that subject/s and exempted from appearing in that subject/s at subsequent examination.

b) Theory and Practical of a particular subject are considered as individual subjects for the purpose of

pass criteria.

c) Those candidates who fail in one or more subjects shall have to appear only in the subject so failed,

in the subsequent examinations.

Conditions under which candidates are permitted to proceed to next higher class

Candidates of I Pharm.D are permitted to carry not more than any two subjects (Two Theory/ Two

Practicals/ One theory & one practical of same or different subjects) to II Pharm.D and appear for II

Pharm.D examination concurrently along with failed subjects of I Pharm.D. However, these

candidates have to pass all the failed subjects of I Pharm.D to become eligible to III Pharm.D.

Declaration of class

Class shall be awarded at the end of I, II, III, IV and V year of Pharm. D. examination as shown

below:

1) Distinction: 75% and above

2) First Class: 60% and above and less than 75%

3) Second class: 50% and above and less than 60%

The result of the successful candidate shall be classified at the end of the final year examination on the

basis of the aggregate of all subjects, theory and practical, secured by the candidate in the I to V year

examinations and completes the course in 5 years, as indicated below.

I Class: 60% and above

II Class: 50%-59%

Candidate securing aggregate of 75% or above marks and have passed in all the subjects in a year in

first attempt shall be declared to have obtained Distinction.

Award of Ranks

Ranks and Medals shall be awarded on the basis of aggregate of all the five university examinations

of Pharm. D. However, candidates who fail in one or more subjects during the Pharm. D. courses shall

not be eligible for award of ranks. Moreover, the candidates should have completed the Pharm. D

course in minimum prescribed number of years, (five years for Pharm. D.) for the award of Ranks.

Award of degree

Candidates who fulfill the requirements mentioned above will be eligible for award of degree during

the ensuing convocation.

Duration for completion of the course of study

The duration for the completion of the course shall be fixed as double the actual duration of the course

and the students have to pass within the said period, otherwise they have to get fresh Registration.

Revaluation /Retotaling of answer papers

There is no provision for revaluation of the answer papers of failed candidates in any examination.

However, the failed candidates can apply for retotaling.

6

Withdrawal from the Program: Students who wish to withdraw from the admitted program after

registration must write a request for withdrawal to the Office of the Principal and later it will be

forwarded to The Registrar, JSS University, Mysore for the approval of the same.

Dismissal: The students who have violated the institutional code of conduct will be dismissed

permanently from their admitted program after conducting meeting in presence of The Principal,

concerned staff members, parents and student. The decision made by the committee will be forwarded

to The Registrar, JSS University, Mysore for the approval of the same.

Readmission after break of study: Candidate who seeks readmission to the course after break of

study has to get the approval from the JSS University, Mysore, by paying a required condonation fee

and no condonation is allowed for the candidate who has more than 2 years of break up period and

he/she has to re-join the course by paying the required fees.

Note: For more details/updates about syllabus and regulations please visit www.jssuni.edu.in

http://www.jssuni.edu.in/

7

Syllabus of III Pharm.D

PHARMACOLOGY – II (THEORY)

Theory: 3 Hrs. /Week

1. Scope and Objectives: This subject will provide an opportunity for the student to learn about the

drug with regard to classification, pharmacodynamics and pharmacokinetic aspects, adverse

effects, uses, dose, route of administration, precautions, contraindications and interaction with

other drugs. In this subject, drugs acting on autacoids, respiratory system, GIT, immune system,

hormones, pharmacology of autacoids and different aspects of genes will be concentrated. In

addition, pharmacology of chemotherapeutic agents and principles of toxicology are also taught.

In addition to theoretical knowledge, the basic practical knowledge relevant to therapeutics will

beimparted.

Upon completion of the subject student shall be able to:

1. Understand the pharmacological aspects of drugs falling under the above mentioned chapters.

2. Carry out the animal experimentsconfidently.

3. Appreciate the importance of pharmacology subject as a basis oftherapeutics.

4. Correlate and apply the knowledge therapeutically.

5. Understand different aspects of genes and their regulatoryfunctions.

2. Lecture wise Programme:

Topics Hrs

1 Pharmacology of drugs acting on Blood and blood forming agents

a) Anticoagulants

b) Thrombolytics and antiplateletagents

c) Haemopoietics and plasmaexpanders

06

2 Pharmacology of drugs acting on Renal System

a) Diuretics

b) Antidiuretics

03

3 Pharmacology of drugs acting on Gastrointestinal Tract

a) Antiulcer drugs,Antacids

b) Laxatives and purgatives

c) Emetics and antiemetics

d) Appetizers, digestants and carminatives

06

8

4 Chemotherapy

a) Introduction

b) Sulfonamides and co-trimoxazole

c) Penicillins andCephalosporins

d) Tetracyclins andChloramphenicol

e) Macrolides, Aminoglycosides, Polyene & Polypeptideantibiotics

f) Quinolines and Fluroquinolines

g) Antifungalantibiotics

h) Antiviralagents

i) Chemotherapy of tuberculosis andleprosy

j) Chemotherapy ofMalaria

k) Chemotherapy of protozoal infections (amoebiasis,giardiasis)

l) Pharmacology of Anthelminticdrugs

m) Chemotherapy of cancer(Neoplasms)

22

5

6

Immunopharmacology

Pharmacology of imunosuppressants and stimulants

Principles of Animal toxicology .

a) Acute, subacute and chronic toxicity.

b) Principles involved in the various toxicity screening methods available for drugs

in the laboratory animals.

03

02

7 The dynamic cell: The structures and functions of the components of the cell

a) Cell and macromolecules: Cellular classification, subcellular organelles,

macromolecules, large macromolecular assemblies

b) Chromosome structure: Pro and eukaryotic chromosome structures, chromatin

structure, genome complexity, the flow of genetic information.

c) DNA replication: General, bacterial and eukaryotic DNA replication.

d) The cell cycle: Restriction point, cell cycle regulators and modifiers.

e) Cell signaling: Communication between cells and their environment, ion-

channels, signal transduction pathways (MAP kinase, P38 kinase, JNK, Ras and

PI3-kinase pathways, biosensors.

11

8 The Gene: Genome structure and function:

a. Gene structure: Organization and elucidation of genetic code.

b. Gene expression: Expression systems (pro and eukaryotic), genetic elements

that control gene expression (nucleosomes, histones, acetylation, HDACS,

DNA binding protein families.

c. Transcription and Transcription factors: Basic principles of transcription in pro

and eukaryotes. Transcription factors that regulate transcription in pro and

eukaryotes.

d. RNA processing: rRNA, tRNA and mRNA processing.

e. Protein synthesis: Mechanisms of protein synthesis, initiation in eukaryotes,

translation control and post-translation events

f. Altered gene functions: Mutations, deletions, amplifications, LOH,

translocations, trinucleotide repeats and other genetic abnormalities.

Oncogenes and tumor suppressor genes.

g. The gene sequencing, mapping and cloning of human disease genes.

h. Introduction to gene therapy and targeting.

i. Recombinant DNA technology: principles. Processes (gene transfer

technology) and applications

18

9 Bio-assay methods

Scope, principles involved in general methods, bioassay designing, applications and

limitations.

04

9

PHARMACOLOGY – II(PRACTICAL)

Practical: 3 Hrs./ PHARMACEUTICAL ANALYSIS(THEORY)


1. Scope and objectives: This course is designed to impart a fundamental knowledge on the art and

science of testing drugs by various instrumental methods of analysis. This focuses on various

modern instruments that are used for testing the purity of drugs in various dosage forms. This

course also gives idea about modern instruments that are used for drug testing like NMR, IR,

Mass, HPLC, HPTLC forms. etc,. It prepares the students for most basics of the applied field

ofpharmacy.

At the end of course, students are able

1. To understand the construction and working of various analyticalinstruments.

2. To know principle and mechanism ofinstrumentation.

3. To understand the different modern techniques of druganalysis.

4. To appreciate the advantages of instrumental methods of druganalysis.

2. Lecture wiseProgramme

1 Quality Assurance:

a. Introduction, sources of quality variation, control of qualityvariation.

b. Validation methods- quality of equipment, validation of equipment and validation

of analytical instruments andcalibration.

03

2. Chromatography: Introduction, history, classification, separation techniques, choice

of methods. The following techniques be discussed with relevant examples of

pharmaceutical products involving principles and techniques of separation of drugs from

excipients.

a. Column Chromatography: Adsorption column chromatography, Operational

technique, frontal analysis and elution analysis. Factors affecting column efficiency,

applications and partition chromatography.

03

b. TLC: Introduction, principle, techniques, Rf value and applications. 02

c. PC: Introduction, principle, types of paper chromatography, preparation techniques,

development techniques, applications.

02

d. Ion-exchange chromatography: Introduction, principles, types of ion exchange

synthetic resins, physical properties, factors affecting ion exchange, methodology

andapplications.

03

e. HPLC: Introduction, theory, instrumentation, and applications. 03

f. HPTLC: Introduction, theory, instrumentation, and applications. 02

g. Gas Chromatography: Introduction, theory, instrumentation-carrier gases, types of

columns, stationary phases in GLC & GSC. Detectors-Flame ionization detectors,

electron capture detector, thermal conductivity detector. Typical gas chromatogram,

derivatisation techniques, programmed temperature gas

chromatography, applications.

04

h. Electrophoresis: Principles of separation, equipment for paper and gel

electrophoresis, and application.

02

i. Gel filtration

applications.

and affinity

chromatography:

Introduction, technique, 03

10

3 Electrometric Methods:

Theoretical aspects, instrumentation, interpretation of data/spectra and analytical

applications be discussed on the following topics.

a. Potentiometry: Electrical potential, electrochemical cell, reference electrodes,

indicator electrodes, measurement of potential and pH, construction and working of

electrodes, Potentiometric titrations, methods of detecting end point, Karl

Fischer titration.

05

b. Conductometry: Introduction, conductivity cell, conductometric titrations and

applications.

03

c. Amperometric Titrations: Introduction, types of electrodes used, referenceand

indicator electrode, instrumentation, titration procedure,

advantages and disadvantages of Amperometry over Potentiometry.

Pharmaapplications.

04

4. Spectroscopy:

Theoretical aspects, instrumentation, elements of interpretation of data/spectra and

application of analytical techniques be discussed on:

a. Absorption Spectroscopy:

Theory of electronic, atomic and molecular spectra. Fundamental laws of photometry,

Beer-Lambert’s Law, application and its deviation, limitation of Beer law, application of

the law to single and multiple component analysis, measurement of equilibrium constant

and rate constant by spectroscopy. Spectra of isolated chromophores, auxochromes,

batho-chromic shift, hypsochromic shift, hyperchromic and hypochromic effect, effect

of solvent on absorption spectra,molecular structure and infrared spectra.

08

Instrumentation – Photometer, U.V.-Visible spectrophotometer – sources of U.V.-

Visible radiations, collimating systems, monochromators, samples cells and following

detectors-Photocell, Barrier layer cell, Phototube, Diode array,

applications of U.V.-Visible spectroscopy in pharmacy and spectrophotometric

titrations.

05

Infrared Spectroscopy: Vibrational transitions, frequency – structure correlations,

Infrared absorption bands, Instrumentation–IR spectro-meter – sources of IR,

Collimating systems, monochromators, sample cells, sample handling in IR

spectroscopy and detectors–Thermocouple, Golay Cells, Thermistor, Bolometer,

Pyroelectric detector, Applications of IR in pharmacy.

06

Fluorimetric Analysis: Theory, luminescence, factors affecting fluorescence,

quenching. Instrumentation, Applications, fluorescent indicators, study of

pharmaceutically important compounds estimated by fluorimetry.

04

b. Flame Photometry: Theory, nebulisation, flame and flame temperature,

interferences, flame spectrometric techniques and instrumentation and

pharmaceuticalapplications.

04

c. Atomic Absorption Spectrometry: Introduction, Theory, types of electrodes,

instrumentation and applications.

d. Atomic Emission Spectroscopy: Spectroscopic sources, atomic emission

spectrometers, photographic and photoelectric detection.

02

11

e. NMR (introduction only):Introduction,theoretical aspects and applications 02

f. Mass Spectroscopy: (Introduction only) – Fragmentation, types of ions produced,

mass spectrum andapplications.

02

12

3.2 PHARMACEUTICAL ANALYSIS(PRACTICAL)

Practical : 3 Hrs./Week List of Experiments:

1. Separation and identification of Amino Acids by PaperChromatography*.

2. Separation and identification of Dyes by radial paperchromatography*.

3. Separation and identification of Sulpha drugs by TLCtechnique*.

4. Effect of pH and solvent on the UV spectrum of givencompound*.

5. Determination of dissociation constant of indicators using UV-Visible spectroscopy*.

6. Conductometric titration of mixture of acids with a strongbase**.

7. Potentiometric titration of strong acid with a strongbase**.

8. Estimation of drugs by Fluorimetrictechnique**.

9. Study of quenching effect influorimetry**.

10. Colorimetric estimation of Supha drugs using BMRreagent**.

11. Simultaneous estimation of two drugs present in givenformulation**.

12. Assay of Dextrose bycolorimetry**

13. Colorimetric estimation of Ferrous ions using1,10-Phenonthroline**.

14. UV spectroscopic estimation of Paracetamoltablets*

15. Determination of Chlorides and Sulphates in Calcium gluconate by Nepheloturbidimetric

Method**.

16. Determination of Na/K by FlamePhotometry**.

17. Determination of pKa using pHmeter*.

18. Infrared spectral graphs/ peak identification of samples with different functional groups (-COOH,

-COOR, -NH2, -NHR, -OH, -CHO,-C=O)

19. Demonstration ofHPLC.

SCHEME OF PRACTICAL EXAMINATION:

Sessional Annual

Synapses 05 10

Major Experiment(Experiment indicated by**) 10 30

Minor Experiment(Experiment indicated by*) 3 20

Viva-Voce 2 10

Max. Marks 20# 70

#Note: Total sessional marks is 30 (20 for practical sessional and 10 marks for regularity, promptness,

viva-voce and record maintenance)

13

3.3 PHARMACOTHERAPEUTICS-II

Theory : 3 Hrs. /Week

1. Scope and Objectives: This course is designed to impart knowledge and skills necessary for

contribution to quality use of medicines. Chapters dealt cover briefly pathophysiology and mostly

therapeutics of various diseases. This willenable the student to understand the pathophysiology of

common diseases and theirmanagement.

Upon completion of the course student shall be able to

1. know the pathophysiology of selected disease states and therationale for drug therapy

2. know the therapeutic approach to management of thesediseases

3. know the controversies in drugtherapy

4. knowtheimportanceofpreparationofindividualised therapeuticplansbasedondiagnosis

5. identify the patient-specific parameters relevant in initiating drug therapy, and monitoring therapy

(including alternatives, time-course of clinical and laboratory indices of therapeutic response and

adverseeffects)

2. Lecture wiseprogramme

Etiopathogenesis and pharmacotherapy of diseases associated with following systems / diseases

No. Topics Hrs

1. Infectious diseases: Guidelines for the rational use of antibiotics and surgical Prophylaxis,

Tuberculosis, Meningitis, Respiratory tract infections, Gastroenteritis, Endocarditis,

Septicemia, Urinary tract infections, Protozoal infection- Malaria, HIV & Opportunistic

infections, Fungal infections, Viral

infections, Gonorrhoea and Syphilis

18

2 Musculoskeletal disorders

Rheumatoid arthritis, Osteoarthritis, Gout, Spondylitis, Systemic lupus

erythematosus.

06

3 Renal system

Acute Renal Failure, Chronic Renal Failure, Renal Dialysis, Drug induced renal

disorders

05

4 Oncology: Basic principles of Cancer therapy, General introduction to cancer

chemotherapeutic agents, Chemotherapy of breast cancer, leukemia.

Management of chemotherapy induced nausea andemesis

06

5 Dermatology: Psoriasis, Scabies, Eczema, Impetigo 04

14

3.3 PHARMACOTHERAPEUTICS-II(PRACTICALS)

Practical : 3 Hrs./Week

Hospital postings for a period of at least one month is required to understand the principles and

practice involved in ward round participation and clinical discussion on selection of drug therapy.

Students are required to maintain a record of 15 cases observed in the ward and the same should

be submitted at the end of the course for evaluation.

ASSIGNMENTS

Students are required to submit written assignments on the topics given to them. Topics allotted

should cover recent developments in drug therapy of various diseases. A minimum of THREE

assignments [1500 – 2000 words] should be submitted forevaluation.

Format of the assignment

- Minimum & Maximum number of pages. - It shall be computer draft copy

- Reference(s) shall be included at the end. - Name and signature of the student

- Assignment can be a combined presentation at

the end of the academic year

- Time allocated for presentation may be

8+2 min

Scheme of Practical Examination

Sessionals Annual

Synopsis 05 15

Major Experiment 10 25

Minor Experiment 03 15

Viva 02 15

Max Marks 20 70

Duration 03hrs 04hrs

* Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity, promptness,

viva-voce and record maintenance)

15

3.4 PHARMACEUTICAL JURISPRUDENCE(THEORY)


1. Scope and Objectives: This course exposes the student to several important legislations related

to the profession of pharmacy in India. The Drugs and Cosmetics Act, along with its amendments

is the core of this course. Other acts, which are covered, include the Pharmacy Act, dangerous

drugs, medicinal and toilet preparation Act etc. Besides this the new drug policy, professional

ethics, DPCO, patent and design Act will bediscussed.

Upon completion of the subject student shall be able to (Know, do, and appreciate) –

1. practice the Professionalethics;

2. understand the various concepts of the pharmaceutical legislation inIndia;

3. know the various parameters in the Drug and Cosmetic Act andrules;

4. know the Drug policy, DPCO, Patent and designact;

5. understand the labeling requirements and packaging guidelines for drugs andcosmetics;

6. be able to understand the concepts of Dangerous Drugs Act, Pharmacy Act and Excise Duties

Act; and

7. other laws as prescribed by the Pharmacy Council of India from time to time including

InternationalLaws.

2. Detailed syllabus and lecture wiseschedule:

Topic Hrs

1. Pharmaceutical Legislations – A brief review.

- Introduction, Study of drugs enquiry committee, Health survey and development committee, Hathi committee and Mudaliar committee

02

2. Code of Pharmaceutical ethics

- Definition, Pharmacist in relation to his job, trade, medical profession and

his profession, Pharmacist’s oath

02

3. Drugs and Cosmetics Act, 1940 and its rules 1945.

- Objectives, Definitions, Legal definitions of schedules to the act andrules

- Import of drugs – Classes of drugs and cosmetics prohibited fromimport, Import under license or permit. Offences andpenalties.

- Manufacture of drugs – Prohibition of manufacture and sale of certain drugs, Conditions

for grant of license and conditions of license for manufacture of drugs, Manufacture of

drugs for test, examination and analysis, manufacture of new drug, loan license and

repackinglicense. Detailed study of schedule M, N and Y. Offences andpenalties

- Sale of Drugs – Wholesale, Retail sale and Restricted license. Offences and penalties

- Labeling & Packing of drugs- General labeling requirements andspecimen labels for

drugs and cosmetics, List of permitted colors. Offences and penalties

- Administration of the act and rules – Drugs Technical Advisory Board, Central drugs

Laboratory, Drugs Consultative Committee, Government analysts, Licensing

authorities, controlling authorities, DrugInspectors

22

4. Pharmacy Act –1948.

Objectives, Definitions, Pharmacy Council of India; its constitution and functions,

Education Regulations, State and Joint state pharmacy councils; its constitution and

functions, Registration of Pharmacists, Offencesand

Penalties.

05

16

5. Medicinal and Toilet Preparation Act –1955.

Objectives, Definitions, Licensing, Manufacture In bond and Outside bond, Export of

alcoholic preparations, Manufacture of Ayurvedic, Homeopathic, Patent &Proprietary

Preparations. Offences and Penalties.

04

6. Narcotic Drugs and Psychotropic Substances Act-1985 and Rules. Objectives,

Definitions, Authorities and Officers, Constitution and Functions of narcotic &

Psychotropic Consultative Committee, National Fund for

Controlling the Drug Abuse, Prohibition, Control and Regulation, opiumpoppy

cultivation and production of poppy straw, manufacture, sale and export of opium,

Offences and Penalties

04

7. Study of Salient Features of Drugs and magic remedies Act and its rules. Objectives, Definitions, Prohibition of certain advertisements, Classes of Exempted advertisements, Offences and Penalties

02

8. Drug Price Control Order & National Drug Policy(Current).

- Objectives, Definitions, Sale prices of bulk drugs, Retail price of formulations, Retail

price and ceiling price of scheduled formulations, Implementation of prices

Fixed/revised.

- Pharmaceutical Policy 2002: Objectives,Approaches in the review, Salient

features of Pharmaceutical Policy 2002.

02

9. Prevention of Cruelty to animals Act-1960.

Objectives, Definitions, Institutional Animal Ethics Committee, Breeding and Stocking of

Animals, Performance of Experiments, Transfer and acquisition of

animals for experiment, Records, Power to suspend or revoke registration, Offences and

Penalties

03

10. Patents & design Act-1970.

- Objectives, definitions, Types of patent, PCT, Patentable and not patentable inventions,

Applications for patents, Term of patent, revocation of patents, compulsory licensing,

Offences and penalties.

- Registration of designs, copyright, prohibition of certain designs, cancellation of designs, Offences and penalties.

03

11. Brief study of prescription and Non-prescription Products. 01

3. Assignments:

Format of the assignment

1. Minimum & Maximum number ofpages

2. It shall be a computer draftcopy

3. Reference(s) shall be included at theend.

4. Name and signature of thestudent

5. Assignment can be a combined presentation at the end of the academicyear.

6. Time allocated for presentation may be 8+2Min

Case studies relating to

1. Drugs and Cosmetics Act and rules along with its amendments, Dangerous Drugs Act, Medicinal

and Toilet Preparation Act, New Drug Policy, Professional Ethics, Drugs (Price control) Order,

Patent and DesignAct.

2. Various prescription and non-prescriptionproducts.

3. Medical and surgicalaccessories.

4. Diagnostic aids and appliances available in themarket.

17

3.5 MEDICINAL CHEMISTRY(THEORY) Theory: 3 Hrs. /Week

1. Scope and Objectives: This course is designed to impart a fundamental knowledge on the

structure and functions of the different drugs. The course gives details of Chemistry, Mechanism

of action, metabolism, adverse effects, Structure Activity Relationships (SAR) and uses of

Chemotherapeutic Agents, Cardiovascular Drugs and synthesis of some important drugs. The

course also covers modern techniques of drug design, which include Prodrug concept and

combinatorialchemistry.

At the end of the course, students are able

1. To understand the chemistry of drugs with respect to their biologicalactivity.

2. To know the metabolism, adverse effect and therapeutic activity ofdrugs.

3. To understand the different modern techniques of drugdesign.

4. To appreciate the SAR of some important drug classes.

2. Lecture wiseProgramme:

Topic Hrs

I Modern concept of rational drug design: A brief introduction to prodrug & drug

latentiation, combinatorial chemistry, general pathways & factors affecting drug

metabolism.

04

II A study of the development of the following classes ofdrugsincluding SAR,

mechanism of action, synthesis of important compounds (marked with asteric*), brand

names of important marketed products and their side effects.

1 Anti-infective agents: 15

a) Local anti-infectiveagents: Alcohols: isopropyl alcohol Phenols: cresols, hexyl resorcinol

Cationic surfactants: benzalkonium chloride, cetylpyridinium bromide Nitrofurans:

nitrofurazone, furazolidone.

b) Antifungalagents: Azoles: miconazole, ketoconazole, fluconazole Miscellaneous:

tolnaftate, naftifine Antifungal Antibiotics: amphotericin, nystatin, griseofulvin.

c) Urinary tract anti-infectives: SAR of quinolone antibacterial agents, Norfloxacin,

ciprofloxacin*, sparfloxacin, ofloxacin,

d) Antitubercular agents: Management of tuberculosis, Synthetic anti TB agents: INH*,

Pyrizinamide, ethambutol, Anti TB antibiotics: rifampin, capreomycine)Antiviral agents

and Anti AIDS agents: amantadine, acyclovir, trifluridine, zidovudine, stavudine

f) Antiprotozoal agents: Introduction to protozoal diseases and causative organisms.

Metronidazole, diloxanidefuroate, dehydroemetine, nifurtimox

g) Anthelmentics: Benzimidazoles: mebendazole, albendazolePiperazine,

diethylcarbamazine, ivermectin

2 Sulfonamides and sulfones

History and development of sulfonamides, SAR and mechanism of action of Sulfonamides,

pKa of Sulfas and Crystalluria.

Sulfamethoxazole, sulfisoxazole, sulfacetamide*, sulfasalzine Folate reductase inhibitors:

trimethoprim*, synergistic action of cotrimoxazole.

Sulfones: dapsone

05

3 Antimalarials:

Etiology of malaria, SAR and mechanism of action of quinolineAntimalarials

Quinine sulphate, Chloroquine phosphate, amodiaquine, pamaquine*, primaquine,

Quinacrine Chloroguanide, cycloguanil, pyrimethamine

05

18

4 Antibiotics

Historical background and classification of antibiotics.

Beta lactam antibiotics: development of acid resistant and extended spectrum Penicillins.

Penicillin G, ampicillin, amoxicillin, cloxacillin Beta lactamase inhibitors: clavulanic acid,

thienamycinCephalosporins: cephelexin, cefadroxil, cefuroxime

Aminoglycosids: streptomycin, neomycin, amikacin, gentamicin Tetracyclines: Chemistry

and SAR of tetracyclines, chlortetracycline, doxycycline, Minocycline.

Macrolides: erythromycin, azithromycin

Miscellaneous: clindamycin, bacitracin, chloramphenicol*

12

5 Antineoplastic agents

Historical background and classification of antineoplastic agents Alkylating agents:

cyclophosphamide, mechlorethamine, cholrambucil Antimetabolites: mercaptopurine,

flurouracil, methotrexate Antibiotics: dactinomycin, mitomycin, streptozocin

Plant products: etoposide, taxol, vincristine and vinblastine Miscellaneous: cisplatin,

interferons

06

6 Cardiovascular agents

a)Antianginal agents and vasodilators Nitrovasodilators: amyl nitrite, isosorbidedinitrate

Calcium channel blockers: verapamil, diltiazem

b)Antiarrhythmic agents:

Class I: quinidine, phenytoin, lidocaine, encainide

Class II: beta blockers- propranolol Class III: amiodarone

Class IV: Calcium channel blockers: verapamil, diltiazem

c)Antihypertensive agents: betablockers: propranolol*,

ACE inhibitors: captopril, enalapril Angiotensin antagonists: losartan

Calcium channel blockers: nifedipine, amlodepine Adrenergic agents: clonidine, methyl

dopa Adrenergic antagonists: prazosin, reserpine

d) Antihyperlipidemic agents: types of hyperlipoproteinemiaclofibrate, fenofibrate,

cholestyramine, lovastatin,simvastatin

Anticoagulants: warfarin, dicumarol,anisindione

12

7. Hypoglycemic agents:

History, development and SAR of sulfonylureas: tolbutamide*, chlorpropamide, glipizide

Metaglinides:repaglinide Thiazolindiones: rosiglitazone, pioglitazone Biguanides:

metformin, phenformin Miscellaneous: acarabose, miglitol

03

8. Thyroid and Antithyroid agents

L-thyroxine, L-threonine

Propyl thiouracil, methimazole

01

9. Diuretics:

Carbonic anhydrase inhibitors: acetazolmide*

Thiazide diuretics: SAR of thiazide diuretics, chlorthiazide, benzthiazide, xipamide,

chlorthalidone

Loop diuretics: frusemide*, ethacrynic acid

Potassium sparing diuretics: spiranolactone,amiloride Miscellaneous: mannitol

05

10. Diagnostic agents

Iodipamide, diatriazoate sodium

Amino hippurate, sulfobromphthalein, fluorescein sodium

02

19

11 Steroidal Hormones and Adrenocorticoids

Estrogens: estradiol, DES

Progestines: progesterone, norethindrone Testosterone, nandralone

Betamethasone, prednisolone, beclomethasone

05

3.5 MEDICINAL CHEMISTRY(PRACTICAL)

Practical: 3 Hrs./Week

List of experiment

No of

classes

A. Assays of important drugs from the course content.

1. Assay of ascorbic acid bycerimetry

2. Assay of metronidazole byNAT

3. Assay of chloroquine phosphate byNAT

4. Assay of dapsone bydiazotization

5. Assay of INH bybromometry

6. Assay of benzyl penicillin byiodometry

7. Assay of analgin byiodimetry

8. Assay of diclofenac byalkalimetry

8

B. Preparation of medicinally important compounds or intermediates required

for synthesis of drugs

1. Preparation of 7-hydroxy 4-methylcoumarin

2. Preparation of phenytoin frombenzoin

3. Preparation of phenothiazine from diphenylamine

4. Preparation of benzyl alcohol frombenzaldehyde

5. Preparation ofchlorbutanol

6. Preparation of eosin fromresorcinol

7. Preparation of fluorescein fromeosin

8. Preparation of triphenyl imidazole frombenzoin

9. Preparation of 2,3 diphenyl quinoxaline fromOPDA

10. Preparation of benztriazole fromOPDA

11. Preparation of benzimidazoles fromOPDA

12. Preparation of sulfanilamide fromacetanilide

13. Preparation ofINH

14. Preparation of cinnamicacid

10

C. Monograph analysis of important drugs.

1. Monograph analysis ofibuprofen

2. Monograph analysis ofaspirin

3. Monograph analysis ofcaffeine

4. Monograph analysis ofsulfanilamide

5. Monograph analysis ofparacetamol

5

D. Determination of partition coefficients, dissociation constants of drug

substances.

2

Scheme of Practical Examination

Sessionals Annual

Synopsis 04 10

Assay/Estimation 06 30

20

Preparation 06 20

Viva 04 10

Max Marks 20 70


* Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity,

21

3. 6 PHARMACEUTICAL FORMULATIONS (THEORY)


1. Scope and Objective: Scope and objectives of the course: Subject deals with the formulation and

evaluation of various pharmaceutical dosageforms.

Upon completion of the course student shall be able to (Know, do, appreciate) –

1. understand the principle involved in formulation of various pharmaceutical dosage forms;

2. prepare various pharmaceuticalformulation;

3. perform evaluation of pharmaceutical dosage forms;and

4. understand and appreciate the concept of bioavailability and bioequivalence, their role in

clinicalsituations.

2. Lecture wiseprogramme: Title of the topic

Topic Hrs

1. Pharmaceutical dosage form- concept and classification 03

2. Tablets: Formulation of different types of tablets, tablet excipients, granulation

techniques, Tablet coating, Type of coating, quality control tests and evaluation for

uncoated and coated tablets.

10

3. Capsules: Production and filling of hard gelatin capsules, Raw materials for shell,

finishing. Production and filling of soft gelatin capsules, Importance of

base adsorption, quality control tests for hard and soft gelatin capsules.

07

4. Liquid orals: Formulation, Manufacturing and evaluation of suspensions,

emulsions and solutions. Instability problems in suspensions and emulsions.

06

5. Parenterals: Definition, types, advantages and limitation, general formulation,

vehicles, production procedure, production facilities, and controls. Formulation of

injections, sterile powders, implants and long acting parenterals, emulsions

and suspensions. Containers and closures pertinent to sterile preparations and

Pharmacopoeial quality control tests, Sterilization and evaluation.

10

6. Semi – Solids: Introduction and classification Factors affecting absorption,

Packaging, storage and labeling.

Ointments: Types of Ointment Base Preparation of ointment. Gels: Types and

formulation of Gels

06

7. Definition and concept of Controlled and novel Drug delivery systems with

available examples, viz. transdermal, buccal, vaginal, nasal, implantable, ocular

drug delivery systems

08

22

3.6 PHARMACEUTICAL FORMULATIONS(PRACTICAL)

Practical: 3 Hrs./Week List of Experiments:

1. Manufacture ofTablets

a. Ordinary compressed tablet-wet granulation

b. Tablets prepared by directcompression.

c. Soluble tablet.

d. Chewable tablet.

2. Formulation and filling of hard gelatincapsules

3. Manufacture ofparenterals

a. Ascorbic acidinjection

b. Calcium gluconateinjection

c. Sodium chlorideinfusion.

d. Dextrose and Sodium chloride injection/infusion.

4. Evaluation of Pharmaceutical formulations (QCtests)

a. Tablets

b. Capsules

c. Injections

5. Formulation of two liquid oral preparations and evaluation byassay

a. Solution: ParacetamolSyrup

b. Antacid suspensions- Aluminum hydroxidegel

6. Formulation of semisolids and evaluation byassay

a. Salicyclic acid and benzoic acidointment

b. Gel formulation Diclofenacgel

7. Cosmetic preparations

a. Lipsticks

b. Cold cream and vanishingcream

c. Clear liquidshampoo

d. Tooth paste and toothpowders.

8. Tablet coating(demonstration) Scheme of PracticalExamination:

Sessionals Annual

Synopsis 05 15

Major Experiment 10 25

Minor Experiment 03 15

Viva 02 15

Max Marks 20 70


Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity,

promptness, viva-voce and record maintenance)

III Pharm D Curriculum & Academic Plan

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23

Details of Subject Teachers

S.

No

.

Name of the

Subject

Name of the

Teacher

Designation and

Department

Mobile

No.

e-mail

1 Pharmacology

-II

Dr. M.Saravanan Lecturer,

Department of

Pharmacology

958562

5948

[email protected]

2 Pharmaceutica

l Analysis

Mr. J S K

Nagarajan

Asst. Professor,

Department of

Pharmaceutical

Analysis

812213

1227

[email protected]

n

3 Pharmacother

apeutics-II

Dr G K

Sadagoban

Lecturer,

Department of

Pharmacy Practice

989487

6656

[email protected]

4 Pharmaceutica

l

Jurisprudence

Dr. Keerthana C Lecturer,

Department of

Pharmacy Practice

887012

0502

[email protected]

5 Medicinal

Chemistry

Dr.Gowramma B Assistant

Professor,

Department of

Pharmaceutical

Chemistry

944211

1172

[email protected]

n

6 Pharmaceutica

l

Formulations

Dr.

R.Sureshkumar

Assitant Professor,

Department of

Pharmaceutics

962954

7089

[email protected]

.in


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24

Academic Plan – IIII Pharm.D

Name of the Subject

Pharmacology II (Theory)

Name of the Faculty

Mr Saravanan J M.Pharm

Designation,

Department

Lecturer, Department of Pharmacology

Mobile Number

9585625948

e-Mail i.d.

[email protected]

Scope, Course Objectives and Course Outcomes

Scope: Pharmacology II provides an opportunity for the students to learn about different classes of

drugs with regard to classification, pharmacodynamic and pharmacokinetic aspects, adverse effects,

uses, dose, route of administration, precautions, contraindications and interaction with other drugs.

Objectives: The primary objectives of this course are to

1. Understand the pharmacological aspects of drugs acting on the renal system, the GI system,

the blood and the immune system.

2. Discuss the pharmacological aspects of chemotherapeutic drugs.

3. Explain the basics of molecular biology.

4. Appreciate the importance of pharmacology subject as a basis of therapeutics.

5. Enable the students to apply theoretical knowledge into clinical practice.

6. Design & execution of animal experiments to identify the pharmacological properties.

Course Outcomes (COs): At completion of this course it is expected that the students will be able to

CO 1 : Identify and explain the pharmacodynamics and pharmacokinetic properties of drugs of

various categories

CO 2 : Recognize the adverse effects of drugs

CO 3 : Avoid adverse drug reactions

CO 4 : Recognize indications of different drugs and avoid contraindications

CO 5 : Provide vital information to patients about drugs during patient counselling

CO 6 : Design & execute animal experiments to identify the pharmacological properties of known

drugs and unknown samples.


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25

LECTURE PLAN

Sessional

No. of Hours of Didactic Lecture

No of Hours

of other

Activities

Total No. of

Lecture Hours

I 32 3 35

II 25 2 27

III 25 3 28

Total No. of Hours 82 08 90

I SESSIONAL: 32 Lectures + 3 Activities

Lecture

No.

Lecture Details Hours

Unit-1: Pharmacology of drugs acting on Renal system

05 1. Diuretics

2. Antidiuretics

Unit-2: Drugs acting on Blood and blood forming agents

08

1. Anticoagulants

2. Haemopoietics

3. Antiplatelet agents

4. Thrombolytic agents

5. Plasma volume expanders

Unit-3: Pharmacology of drugs acting on Gastrointestinal Tract

08

1. Antiulcer drugs

2. Laxatives and purgatives

3. Emetics and antiemetics

4. Appetizers, digestants and carminatives

Unit-4: Chemotherapy

11

1. Introduction, classification & general mechanism of action to chemotherapeutic

agents

2. Sulfonamides & Co-trimoxazole

3. Tetracylines

4. Chloramphenicol

5. Penicillins

6. Aminoglycoside antibiotics

7. Macrolides

8. Polyene and Polypeptide antibiotics

9. Quinolines and Fluroquinolines

10. Antiprotozoal drugs

11. Anthelmintic drugs


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26

Activity1 MCQ Test

Activity2 MCQ Test

Activity3 MCQ Test

II SESSIONAL: 25 Lectures + 2 Activities

Lecture

No.


Unit-4: Chemotherapy

10

1. Antiviral agents

2. Antifungal agents

3. Chemotherapy of tuberculosis

4. Chemotherapy of leprosy

5. Chemotherapy of Malaria

6. Chemotherapy of cancer

Unit-5: Immunopharmacology

03

1. Pharmacology of Immunosuppressants

2. Pharmacology of Immunosuppressants

Unit-6: Principles of Animal toxicology

02

1. Acute, sub-acute & Chronic Toxicity study

2. Principle involved in the various toxicity screening methods available for drugs

in the laboratory animals.

Unit-7 : The dynamic cell: Structure & functions of the components of the cell

10

1. Cell and macromolecules

2. Chromosome structure

3. DNA Replication

4. The Cell Cycle

Activity-

1

MCQ Test

Activity-

2

MCQ Test

III SESSIONAL: 25 Lectures + 3 Activities

Lecture

No.


Unit-7 : The dynamic cell: Structure & functions of the components of the cell

04 1. Cell Signalling

2. Biosensors

Unit-8: The Gene: Genome structure and function

3. Gene structure: Organization and elucidation of genetic code

4. Gene Expression

5. Transcription & transcription factors


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27

6. Processing of RNA 19

7. Protein Synthesis

8. Mutations

9. Oncogenes & tumor suppressor genes

10. Gene Sequencing & Gene Mapping

11. Gene Therapy

12. Recombinant DNA Technology

Unit-9 Bioassay methods

02 1. Introduction and scope of bioassay

2. Principles of bioassay

3. Types, applications & limitations of bioassay

Activity

1

Unit Test – 1

Activity

2

Unit Test – 2

Activity

3

Unit Test – 3

Text Books

1. Tripathi, K. D. Essentials of medical pharmacology. 4th Ed, 1999. Publisher: Jaypee, Delhi.

2. Satoskar, R.S. and Bhadarkar, S.D. Pharmacology and pharmacotherapeutics. 16th edition

(single volume), 1999. Publisher: Popular, Dubai.

3. Rang, H.P. & Dale, M.M. Pharmacology. 4th edition, 1999. Publisher: Churchill Living

stone. Cilincal Pharmacokinetics, Concepts and Applications: By Malcolm Rowland and

Toezer.

Reference Books

1. Gilman’s The Pharmacological Basis of therapeutics. 9th Ed, 1996. Publisher Mc Graw Hill,

Pergamon press.

2. Craig, C.R.&Stitzel, R.E. Modern Pharmacology. Latest edition. Publisher: Little Brown.Co

3. Katzung, B.G. Basic and clinical pharmacology. Latest edition. Publisher: Prentice Hall, Int.

4. Shargel and Leon. Applied Biopharmaceutics and pharmacokinetics. Latest edition. Publisher:

Prentice Hall, London.

*** *** **


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28

Name of the Subject

Pharmaceutical Analysis (Theory)

Name of the Faculty

Dr. Nagarajan JSK M.Pharm., Ph.D

Designation,

Department

Assistant Professor, Department of

Pharmaceutical Analysis

Mobile Number

9443149945

e-Mail i.d.

[email protected]


Scope: This course is designed to impart a fundamental knowledge on the art and science of testing

drugs by various instrumental methods of analysis. This focuses on various modern instruments that

are used for testing the purity of drugs in various dosage forms. This course also gives idea about

modern instruments that are used for drug testing like NMR, IR, Mass, HPLC, HPTLC forms. etc., It

prepares the students for most basics of the applied field of pharmacy.


1. To understand the principle, construction and working of various analytical instruments

2. Help the students to understand the concepts of pharmaceutical analysis

3. Discuss the fundamentals of Instrumentation Techniques like Chromatography and

spectroscopy

4. Equip the students to analyse the drug or drugs by using different analytical instruments.

5. The students will learn the importance of Quality assurance in the pharma field.

6. The students also learn the importance of Calibration and validation to be performed for the

instruments.


CO 1 : The importance of Quality in Pharmaceuticals.

CO 2 : The students will gain appropriate knowledge about appropriate analytical skills required

for the analysis of API and formulations.

CO 3 : To understand the basic knowledge on assay of single and multiple component

pharmaceuticals by using various analytical instruments

CO 4 : To develop basic practical skills using instrumentation techniques parameters

LECTURE PLAN


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29

Sessional No. of Hours of Didactic

Lecture

No of Hours of other

Activities

Total No. of Lecture

Hours

I 26 3 29

II 27 3 30

III 18 9 27

Total No. of

Hours

71 15 76


Lecture

No.


PHARMACEUTICAL ANALYSIS

Intro Orientation to the Pharmaceutical Analysis 01

Quality Assurance:

03

6. Introduction, sources of quality variation,

7. Control of quality variation. Validation Methods, Quality of equipment,

8. validation of equipment and validation of analytical instruments and calibration.

Activity

-1

MCQ Test on Quality Assurance

Chromatography: Introduction, history, classification, separation, techniques, choice of

methods. The following techniques be discussed with relevant examples of pharmaceutical

products involving principles and techniques of separation of drugs from excipients

Paper Chromatography

02 4. Introduction, principle, types of paper chromatography, preparation techniques.

5 Development techniques, applications.

Thin Layer Chromatography

02 6 Introduction, Principle, Techniques

7 Techniques, Rf value and applications.

Activity-

2

MCQ TEST(paper chromatography & TLC)

Column Chromatography

03

8 Adsorption column chromatography, Operational technique.

9 Frontal analysis and Elution analysis. Factors affecting column efficiency.

10 Applications and partition chromatography.

High Performance Liquid Chromatography

03

11 Introduction, Theory.

12 Instrumentation

13 Instrumentation and applications.

High Performance Thin Liquid Chromatography 02

14 Introduction, theory

15 Instrumentation, and applications.

Gas Chromatography: 04

16 Introduction, theory, instrumentation..

17 Carrier gases, types of columns, stationary phases in GLC & GSC..

18 Detectors-Flame ionization detectors, electron capture detector, thermal


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30

conductivity detector.

19 Typical gas chromatogram, derivatisationtechniques, programmed temperature,

applications.

Ion-Exchange chromatography: 03

20 Introduction, principles, types of ion exchange synthetic resins.

21 Types of ion exchange synthetic resins, physical properties, factors affecting ion

exchange.

22 Methodology andapplications.

Gel Filtration & Affinity chromatography 02

23 Gel filtration applications.

24 Affinity Chromatography: Introduction,technique,

Electrophoresis

02 25 Principles of Separation, Equipment for Paper

26 Gel electrophoresis and Application


Lecture No. Lecture Details Hours

Spectroscopy: Theoretical aspects, instrumentation, elements of interpretation of

data/spectra and application of analytical techniques be discussed on:

08

27 Theory of electronic, atomic spectra

28 Theory of molecular spectra

29 Fundamental laws of photometry, Beer-Lambert’s Law, application and its

deviation, limitation of Beer law

30 Application of the law to single and

31 Multiple component analysis

32 Measurement of equilibrium constant and rate constant by spectroscopy.

33 Spectra of isolated chromophores, auxochromes, batho-chromic shift,

hypso chromic shift, hyper andhypo chromic shift,.

34 Solvent on absorption spectra, molecular structure and infrared spectra

Instrumentation – UV-Visible

05

35 Sources of U.V.-Visible radiations, collimating systems

36 Monochromators, samples cells and following detectors-Photocell,

37 Barrier layer cell, Phototube,

38 Diode array, applications of U.V.-Visible spectroscopy in pharmacy.

39 Spectrophotometric titrations

IR Spectrsocopy

06

40 Vibrational transition and frequence, Structure correlations, Infrared

absorption bands,

41 Instrumentation–IR spectrometer – sources of IR, Collimating systems,

42 Monochromators, sample cells, sample handling in IR spectroscopy

43 Detectors Thermocouple, Golay Cells, Thermistor,

44 Bolometer, Pyroelectric detector,.

45 Applications of IR in pharmacy

Fluorimetry


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46 Principle, Theory, luminescence 04

47 Factors affecting fluorescence, quenching. Instrumentation

48 Applications, fluorescent indicators

49 Study of pharmaceutically important compounds estimated by fluorimetry.

Flame Photometry

04 50 Principle, Theory, nebulisation, flame and flame temperature

51 Interferences, flame spectrometric techniques

52 Instrumentation, and detectors

53 Pharmaceutical applications

Activity-1 MCQ - Test

Activity-2 MCQ - Test

Activity-3 MCQ -Test



Atomic Absorption Spectroscopy

02 54 Introduction, Theory, types of electrodes

55 Instrumentation and applications

NMR

02 56 Introduction and principle

57 Theoretical aspects and applications

MASS Spectroscopy

02 58 Fragmentation, types of ions produced

59 Mass spectrum and applications

Electrometric Titrations: Theoretical aspects, instrumentation, interpretation of

data/spectra and analytical applications be discussed on the following topics

05

60 Potentiometric Titrations: Electrical potential, electrochemical cell

61 Reference electrodes, indicator electrodes

62 Measurement of potential and pH, construction and working of electrodes

63 Potentiometric titrations, methods of detecting end point

64 Karl Fischer titration

Conductometric Titrations

03

65 Introduction and principle

66 Conductivity cell, conductometric titrations

67 Application

Amperometric Titrations

04

68 Introduction and principle

69 Types of electrodes used, reference and indicator electrode

70 Instrumentation, titration procedure, advantages and disadvantages

71 Amperometry over Potentiometry. Pharma applications

Activity 1 Descriptive test on QA

Activity 2 Descriptive test on Chromatography(PC, TLC, CC and IEC)

Activity 3 Descriptive Test on Chromatography (HPLC,GC and HPTLC)

Activity 4 Descriptive Test on Chromatography (


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32

Activity 5 Descriptive Test on Chromatography (HPLC,GC and HPTLC)

Activity 6 MCQ Test -1



Activity 9 Revision Exam – 1

Course materials:

Text books 1. Instrumental methods of analysis by Willard, Merit, Dean and Settle 6thedition

2. Practical Pharmaceutical Chemistry Vol-II- Beckett and Stenlake 3rdedition

Reference books 1. Text book of quantitative chemical analysis by A.I.Vogel

2. Text book of Pharmaceutical Analysis by K.A.Cannors

3. Pharmaceutical analysis by Skoog andWest.

4. Spectroscopy by William Kemp.

Name of the Subject

Pharmacotherapy II (Theory)

Name of the Faculty

Dr. G K Sadagoban., Pharm.D

Designation,

Department

Lecturer, Department of Pharmacy Practice

Mobile Number

9894876656

e-Mail i.d.

[email protected]


Scope: This course is designed to impart knowledge and skills necessary for contribution to quality

use of medicines. Chapters dealt cover briefly pathophysiology and mostly therapeutics of various

diseases. This will enable the student to understand the pathophysiology of common diseases and their

management.


1. Know the pathophysiology of selected disease states and the rationale for drug therapy

2. Know the therapeutic approach to management of these diseases

3. Know the controversies in drug therapy

4. Know the importance of preparation of individualized therapeutic plans based on diagnosis


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33

5. Identify the patient-specific parameters relevant in initiating drug therapy, and monitoring

therapy (including alternatives, time-course of clinical and laboratory indices of therapeutic

response and adverse effects)


CO1: Students will be able to describe the pathophysiology and management of infectious,cancer,

renal failure and diseases

CO2: Students will be developing Patient case based Assessment Skills

CO3: Students will be able to describe the quality use of medicines issues surrounding the

therapeutic agents in the treatment of diseases

CO4: Students will have developed clinical skills in the therapeutic management of these conditions.

CO5: Continue to develop communication skills.

CO6: Students will provide patient – centered care to diverse patients using the evidence based

medicine

LECTURE PLAN

Sessional


No of Hours

of other

Activities

Total No. of

Lecture Hours Pharmacotherapy II

I 26 03 29

II 26 03 29

III 23 03 26



Lecture

No.


PHARMACOTHERAPY II (26)

Unit-1: Infectious Disease

26 1. Orientation to the subject

Guidelines for the rational use of antibiotics and surgical Prophylaxis

2. Tuberculosis

3. Meningitis

4. Respiratory tract infections

5. Gastroenteritis

6. Endocarditis

7. Septicemia

8. Urinary tract infections

9. Protozoal infection- Malaria

10. HIV & Opportunistic infections


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34

11. Fungal infections

12. Viral infections

13. Gonorrhea

14. Syphilis

Activity- 1 Online Course

Activity- 2 MCQ Test

Activity- 3 Assignment


Lecture

No.



Unit-2: Musculoskeletal disorders

12 1. Rheumatoid arthritis

2. Osteoarthritis

3. Gout

4. Spondylitis

5. Systemic lupus erythematosus

Unit-3: Renal system

14 1. Acute Renal Failure

2. Chronic Renal Failure

3. Renal Dialysis

4. Drug induced renal disorders





Lecture

No.



Unit-4: Oncology

15 1. Basic principles of Cancer therapy

2. General introduction to cancer chemotherapeutic agents

3. Chemotherapy of breast cancer

4. Chemotherapy of leukemia.

5. Management of chemotherapy induced nausea and emesis

6. Software and case studies

Unit-4: Dermatology

1. Psoriasis

08 2. Scabies

3. Eczema

4. Impetigo


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35




Text Books

1. Clinical Pharmacy and Therapeutics - Walker and Whittlesea, Churchill Livingstone

Publication

Reference Books

1. Pharmacotherapy: A Pathophysiologic approach - Joseph T. Dipiro et al. Appleton & Lange

2. Clinical Pharmacy and Therapeutics - Eric T. Herfindal, Williams and Wilkins Publication

3. Applied Therapeutics: The clinical Use of Drugs. Lloyd Young and Koda-Kimble

*** *** *

Name of the Subject

Pharmaceutical Jurisprudence (Theory)

Name of the Faculty

Dr. Keerthana C Pharm.D

Designation, Department

Resident, Department of Pharmacy Practice

Mobile Number

8870120502

e-Mail i.d.

[email protected]

Scope: This course exposes the

student to several important legislations related to the profession of pharmacy in India. The Drugs and

Cosmetics Act, along with its amendments is the core of this course. Other acts, which are covered,

include the Pharmacy Act, dangerous drugs, medicinal and toilet preparation Act etc. Besides this the

new drug policy, professional ethics, DPCO, patent and design Act will be discussed.

Course Objectives: The primary objectives of this course are to

1. Discuss the various concept of the pharmaceutical legislation in India

2. Help the students to understand the parameters involved in the Drugs and Cosmetics Act and

rules

3. Discuss and understand the professional ethics



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36

4. Familiarize the concept of Drug Policy, Drug Price Control Order, Patent and Design Act,

Drugs and Magic Remedies Act

5. Help the students to understand the concepts of Narcotics and Psychotropic substances Act,

Pharmacy Act and Excise duties Act

6. Equip the students to prepare label and packaging for any given drug using the guidelines

under Drug and Cosmetics Act.


CO 1: Define the concepts of the pharmaceutical legislation in India

CO 2: Practice the professional ethics in pharmacy field and ethics involved in Prevention of

Cruelty to animals

CO 3: Define the concepts of Drug Policy, Drug Price Control Order, Patent and Design Act,

Drugs and Magic Remedies Act

CO 4: Critically interpret the various schedules involved the Drugs and Cosmetics Act, Narcotics

and Psychotropic Substances Act

CO 5: Apply the basic concepts of labelling and packaging of drugs

CO 6: Define the concepts of Pharmacy Act, Medicinal and Toilet Preparation Act

LECTURE PLAN

Sessional


No of Hours of

other

Activities

Total No. of

Lecture Hours

Pharmaceutical Jurisprudence

I 18 2 20

II 16 2 18

III 16 2 18

Total No. of

Hours

50 6 56


Lecture

No.


Unit-1: Pharmaceutical Legislations

(03)

1. Introduction

2. Drugs Enquiry Committee, Health Survey and Development Committee

3. Hathi committee and Mudaliar Committee

Unit-2: Code of Pharmaceutical Ethics (02)

1. Definition, Pharmacist in relation to his Job

2. Pharmacist in relation to his Trade, Medical profession and his profession,

Pharmacist Oath


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37

Unit-3: Drugs and Cosmetics Act, 1940 and its Rules 1945

(13)

1. Objectives and Definitions

2. Legal definitions of schedules to the act and rules. Study of Schedule’s with

reference to Schedule B, C & C1, D, E1, F&F1, F2, F3, FF, G, H, J, K, M, N,

P, R, V, W, X, Y.

3. Import of Drugs

4. Procedure, Offences & Penalties to Import of Drugs

5. Manufacture of Drugs

6. Loan License & Repacking License

7. Sale of Drugs: Wholesale of Drugs, Retail Sale & Restricted Licenses

8. Offences & Penalties Relating to Manufacture and Sale of Drugs

9. Labelling & Packing of Drugs

10. Special Labelling Requirements

11. Administration of the Act and Rules

12. Functions of DTAB, DCC, CDL

13. Qualification and duties of Government Analyst & Drug Inspector

Activity-

1

MCQ Test on Drugs and Cosmetics Act

Activity-

2

MCQ Test on Pharmaceutical Legislations and Code of Pharmaceutical Ethics

II SESSIONAL : 16 Lectures + 2 Activities

Lecture

No.


Unit-4: Pharmacy Act,1948

(03)

1. Objectives, Legal Definitions, General Study

2. Constitution and Functions of State & Central Council

3. Registration and Procedure, Education Regulations

Unit-5: Medicinal and Toilet Preparation Act, 1955

(06)

1. Objectives, Legal Definitions, Levy and Collection of Duties

2. Licensing

3. Manufacture In bond and Outside bond

4. Ware Housing

5. Export of Alcoholic Preparations

6. Manufacture of Ayurvedic, Homeopathic, Patent & Proprietary Preparations,

Offences & Penalties

Unit-6: Narcotic Drugs and Psychotropic Substances Act-1985 and Rules (05)

1. Objectives, Legal Definitions, General Study

2. Authorities and Officers, Constitution and Functions of Narcotic &

Psychotropic Consultative Committee, National Fund for Controlling the Drug

Abuse

3. Prohibition, Control and Regulation

4. Offences and Penalties

5. Opium Poppy Cultivation, Production, Manufacture, Sale and Export,

Schedules to the Act

Unit-7:Drugs and Magic Remedies Act and its Rules

(02) 1. Definitions, Prohibition of certain advertisements

2. Classes of Exempted advertisements, Offences and Penalties

Activity-

1

MCQ Test on II Sessional Portions


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38

Activity-

2

Group Discussion

III SESSIONAL : 16 Lectures + 2 Activities

Lecture

No.


Unit -8: Drug Price control Order & National Drug Policy (Current)

(05)

1. Objectives, Definitions

2. Sale prices of bulk drugs, Retail price of formulations, Retail price and ceiling

price of scheduled formulations,

3. Implementation of prices Fixed/ revised.

Pharmaceutical Policy 2002

1. Objectives, Approaches in the review

2. Salient features of Pharmaceutical Policy 2002

Unit-9:Prevention of Cruelty to Animals Act, 1960

(05) 1. Definitions, Cruelty to Animals

2. IAE Committee, Breeding and Stocking of Animals

3. Performance of Experiments

4. Breeding and Stocking of Animals, Performance of Experiments , Transfer

and Acquisition of Animals for Experiment

5. Records, Power to suspend or revoke registration, Offences and Penalties

Unit-10: Patents & Design Act,1970

(05)

1. Definitions, Types of Patents, Patent Cooperative Treaty

2. Patentable Invention, Inventions not Patentable

3. Application for Patent, Grant of a Patent, Rights

4. Term of Patent, Revocation of Patents, Compulsory Licences, Offences and

Penalties

5. Registration of designs, copyright, prohibition of certain designs, cancellation

of designs, Offences and penalties.

Unit 11-Brief Study of Prescription and Non- Prescription Products

(01) 1. Prescription Products & Non- Prescription Products

Activity-

1

MCQ Test on III Sessional Portions

Activity-

2

Test on III Sessional Portions

Text books (Theory)

1. Mithal , B M. Textbook of Forensic Pharmacy. Calcutta :National; 1988.

2. Jain, NK. A Textbook of forensic pharmacy. Delhi: VallabhPrakashan ; 1995

Reference books (Theory)

1. Singh, KK, editor. Beotra’s the Laws of Drugs, Medicines & cosmetics. Allahabad: Law

Book House; 1984.

2. Reports of the Pharmaceutical enquiry Committee

3. I.D.M.A., Mumbai. DPCO 1995

4. Various reports of Amendments.

5. Deshapande, S.W. The drugs and magic remedies act 1954 and rules 1955. Mumbai: Susmit

Publications; 1998.


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6. Eastern Book Company . The narcotic and psychotropic substances act 1985, Lucknow:

Eastern; 1987.

*** *** ***

Name of the Subject

Medicinal Chemistry (Theory)

Name of the Faculty

Dr. B. GowrammaM.Pharm., Ph.D

Designation,

Department


Pharmaceutical Chemistry

Mobile Number

9442111172

e-Mail i.d.

[email protected]


Scope: This subject is designed to impart fundamental knowledge on the structure, chemistry and

therapeutic value of drugs. The subject emphasizes on structure activity relationships of drugs,

importance of physicochemical properties and metabolism of drugs. The syllabus also emphasizes on

chemical synthesis of important drugs under each class.

mailto:[email protected]


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40

Objectives: Upon completion of the course the student shall be able to

1. understand the chemistry of drugs with respect to their pharmacological activity

2. understand the drug metabolic pathways, adverse effect and therapeutic value of drugs

3. know the Structural Activity Relationship (SAR) of different class of drugs

4. write the chemical synthesis of some drugs


CO 1: Helps in correlating between pharmacology of a disease and its mitigation or cure.

CO 2: To understand the drug metabolic pathways, adverse effect and therapeutic value of drugs

CO 3: To know the structural activity relationship of different class of drugs.

CO 4: Well acquainted with the synthesis of some important class of drugs.

CO 5: Knowledge about the mechanism pathways of different class of medicinal compounds.

CO 6: To understand the chemistry of drugs with respect to their pharmacological activity.

LECTURE PLAN

Sessional

No. of Hours of

Didactic Lecture

No of Hours of

other Activities

Total No. of

Lecture Hours

I 25 04 29

II 26 02 28

III 25 02 27




Introduction to Medicinal Chemistry

01 1. Introduction to Medicinal Chemistry

Unit-1: Modern concept of rational drug design

04

1. A brief introduction to prodrug & drug latentiation,

2. A brief introduction to drug latentiation,

3. Combinatorial Chemistry

4. General pathways & factors affecting drug metabolism

Unit-2: A study of the development of the following classes of drugs including SAR,

mechanism of action, synthesis of important compounds (marked with asteric*), brand

names of important marketed products and their side effects.

15 1. Anti-infective agents

5. a) Local anti-infective agents: Phenols, alcohols

6. Cationic surfactants: benzalkonium chloride, cetylpyridinium bromide


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41

7. b) Antifungal agents: Azoles: miconazole, ketoconazole, fluconazole

8. Miscellaneous: tolnaftate, naftifine

9. Antifungal Antibiotics: amphotericin, nystatin, griseofulvin

10. c) Urinary tract anti-infectives:

SAR of quinolone antibacterial agents, Norfloxacin, ciprofloxacin*,

11. sparfloxacin, ofloxacin

12. d) Antitubercular agents:

Management of tuberculosis

13. Synthetic anti TB agents: INH*, Pyrizinamide, ethambutol

14. Anti TB antibiotics: rifampin, capreomycin

15. e) Antiviral agents and Anti AIDS agents: amantadine, acyclovir, trifluridine,

zidovudine, stavudine

16. f) Antiprotozoal agents: Introduction to protozoal diseases and causative

organisms.

17. Metronidazole, diloxanidefuroate, dehydroemetine, nifurtimox

18. g) Anthelmentics: Benzimidazoles: mebendazole, albendazole

19. Piperazine, diethylcarbamazine, ivermectin

2. Sulfonamides and sulfones

05

12. History and development of sulfonamides, SAR and mechanism of action of

Sulfonamides, pKa of Sulfas and Crystalluria

13. Sulfamethoxazole, sulfisoxazole

14. sulfacetamide*, sulfasalazine

15. Folate reductase inhibitors: trimethoprim*, synergistic action of

Cotrimoxazole

16. Sulfones: dapsone

Activity-1 MCQ Test

Activity-2 MCQ Test

Activity-3 MCQ Test

Activity-4 MCQ Test


Lecture

No.


3. Antimalarials

7. Etiology of malaria, SAR and mechanism of action of

quinolineAntimalarials


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8. Quinine sulphate, Chloroquine phosphate,

05

9. Amodiaquine, pamaquine*

10. Primaquine, Quinacrine

11. Chloroguanide, cycloguanil, pyrimethamine

4. Antibiotics

12

3. Historical background, Classification of antibiotics

4. Betalactam antibiotics: Development of acid resistant and extended spectrum

Penicillins.

5. Penicillin G, ampicillin, amoxicillin, cloxacillin

6. Beta lactamase inhibitors:

7. clavulanic acid, thienamycin

8. Aminoglycosids: streptomycin, neomycin,

9. Amikacin, gentamicin

10. Tetracyclines: Chemistry and SAR of tetracyclines

11. Chlortetracycline, doxycycline, Minocycline

12. Macrolides: erythromycin, azithromycin

13. Miscellaneous: clindamycin, bacitracin

14. chloramphenicol*

5. Antineoplastic agents

06

3. Historical background and classification of antineoplastic agents

4. Alkylating agents: cyclophosphamide, mechlorethamine, Cholrambucil

5. Antimetabolites: mercaptopurine, flurouracil, methotrexate

6. Antibiotics: dactinomycin, mitomycin, streptozocin

7. Plant products: etoposide, taxol, vincristine and vinblastine

8. Miscellaneous: cisplatin, interferons

6. Hypoglycemic agents

03 5. History, development and SAR of

6. sulfonylureas: tolbutamide*, chlorpropamide, glipizide, Metaglinides:

repaglinide

7. Thiazolindiones: rosiglitazone, pioglitazone Biguanides: metformin,

phenformin Miscellaneous: acarabose, miglitol


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43

Activity-1 MCQ Test

Activity-2 MCQ Test


Lecture

No.


9. Thyroid and Antithyroid agents

01 13. L-thyroxine, L-threonine, Propyl thiouracil, methimazole

10. Diuretics

05

4. Carbonic anhydrase inhibitors: acetazolmide*

5. Thiazide diuretics: SAR of thiazide diuretics, chlorthiazide, benzthiazide,

xipamide, chlorthalidone

6. Loop diuretics: frusemide*, ethacrynic acid

7. Potassium sparing diuretics: spironolactone, amiloride

8. Miscellaneous: mannitol

11. Diagnostic agents

02 1. Iodipamide, diatriazoate sodium Amino hippurate,

2. sulfobromphthalein, fluorescein sodium

12. Steroidal Hormones and Adrenocorticoids

05

1. Estrogens: estradiol, DES Progestines: progesterone, norethindrone

2. Testosterone, nandralone

3. Betamethasone

4. Beclomethasone

5. Prednisolone

13. Cardiovascular agents

1. a) Antianginal agents and vasodilators Nitrovasodilators: amyl nitrite,

isosorbidedinitrate

12

2. Calcium channel blockers: verapamil, diltiazem

3. b) Antiarrhythmic agents: Class I: quinidine, phenytoin, lidocaine, encainide

4. Class II: beta blockers- propranolol

5. Class III: amiodarone

6. Class IV: Calcium channel blockers: verapamil, diltiazem

7. c) Antihypertensive agents: betablockers: propranolol* ACE inhibitors:


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44

captopril, enalapri

8. Angiotensin antagonists: losartan

Calcium channel blockers: nifedipine, amlodipine

9. Adrenergic agents: clonidine, methyl dopa

10. Adrenergic antagonists: prazosin, reserpine

11. d) Antihyperlipidemic agents: types of hyperlipoproteinemiaclofibrate

12. fenofibrate, cholestyramine, lovastatin, simvastatin

Activity-1 MCQ Test

Activity-2 MCQ Test

Text Books

1. Wilson and Giswold’s Organic medicinal and Pharmaceutical Chemistry.

2. Organic Chemistry by I.L. Finar, Vol. II.

3. The Organic Chemistry of Drug Synthesis by Lednicer, Vol. 1-5.

4. Indian Pharmacopoeia.

5. Text book of practical organic chemistry- A.I.Vogel.

Reference Books

1. Foye’s Principles of Medicinal Chemistry.

2. Burger’s Medicinal Chemistry, Vol I to IV.

3. Introduction to principles of drug design- Smith and Williams.

4. Remington’s Pharmaceutical Sciences.

5. Martindale’s extra pharmacopoeia.94

Name of the Subject

Pharmaceutical Formulation

Name of the Faculty

Dr. R.SureshkumarM.Pharm., Ph.D

Designation,

Department


Pharmaceutics

Mobile Number

9865064872

e-Mail i.d.

[email protected]



(2020-21)

45

Scope: This course is designed to impart knowledge about pharmaceutical dosage forms. It also deals

with the formulation and evaluation of various pharmaceutical dosage forms


7. Gain knowledge on the form in which the drugs are available in the market

8. Reasons/Necessary to convert into a dosage form

9. To acquire knowledge on formulation of conventional drug delivery system

10. To acquire knowledge on Novel drug delivery system

Course Outcomes (COs): Upon completion of the subject student shall be able to (Know, do, appreciate) –

CO1: Understand the principle involved in formulation of various pharmaceutical dosage forms;

CO2: Prepare various pharmaceutical formulations

CO3: Perform evaluation of pharmaceutical dosage forms; and

CO4: Understand and appreciate the concept of bioavailability and bioequivalence, their role in

clinical situations

LECTURE PLAN – Abstract

Sessional

No. of Hours of Didactic

Lecture

No of Hours of other

Activities

Total No. of

Lecture Hours

Pharmaceutical

Formulation

I 22 6 28

II 15 4 19

III 13 13 26


I SESSIONAL : 22 Lectures + 6Activities

Lecture

No.


PHARMACEUTICAL DOSAGE FORM

Unit-1: Pharmaceutical dosage form

02 1.1 concept and classification

Unit-2: Tablets

10

2.1 Introduction

2.2 Formulation of different types of tablets

2.3 Tablet excipients

2.4 Granulation techniques

2.5 Quality control and evaluation of tablets

2.6 Tablet coating- Theory


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2.7 Types of coating

2.8 Quality control tests for coated tablet

Unit-3: Capsules

10

3.1 Production of gelatin

3.2 Production of Hard Gelatin Capsules

3.3 Filling of Hard Gelatin capsules

3.4 Quality control tests for capsules

3.5 Production and filling of soft gelatin capsules

3.6 Quality control tests for soft gelatin capsules

Activity1 Mind Mapping on Selected Topic

Activity2 MCQ Test

Activity3 MCQ Test

Activity4 Revision-1



II SESSIONAL : 15 Lectures + 4 Activities

Lecture

No.


Unit-4: Liquid orals

10

4.1 Formulation and evaluation of suspensions

4.2 Formulation and evaluation of Emulsions

4.3 Formulation and evaluation of Solutions

4.4 Stability of Liquid orals

Unit-5: Parenterals

05

5.1 Introduction

5.2 Containers used for Parenterals

5.3 Formulation of large and small volume

5.4 Sterilization

5.5 Quality control tests for Parenterals

Activity-

1

MCQ Test

Activity-

2

MCQ Test

Activity-

3

Revision Test 1

Activity- Revision Test 2


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47

4

III SESSIONAL : 13 Lectures + 13 Activities

Lecture

No.


Unit-6: Semi – Solids

05

6.1 Introduction and classification

6.2 Factors affecting absorption and anatomy of skin

6.3 Packaging storage and labeling

6.4 Ointments - Different types of bases

6.5 Preparation of ointment

6.6 Jellies and Types of jellies Formulation

6.7 Suppositories- Formulation and Packaging

Unit: 7-Novel Drug delivery systems

08

7.1 Definition and concept of Controlled release

7.2 Trans dermal DDS

7.3 Buccal DDS

7.4 Rectal-DDS

7.5 Nasal DDS

7.6 Ocular DDS

7.7 Vaginal DDS

Activity 1 Unit Test – 1








Activity 9 MCQ Test-4





Text Books

1. Formulative and Industrial Pharmacy., Leon Lachmann/Liebermann’s.

2. Pharmaceutical Dosage forms and drug delivery system ., Ansel


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3. Pharmaceutical dosage forms, Vol, I,II and III by lachman

4. Rowlings Text book of Pharmaceutics c. Tutorial Pharmacy – Cooper &Gun

Reference books (Theory)

a. Remington’s Pharmaceutical Sciences

b. USP/BP/IP

*** *** ***

III Pharm D Curriculum & Academic Plan (2020-21)

49

JSS COLLEGE OFPHARMACY, ROCKLANDS,OOTY

ACADEMICYEAR 2020-21: PHARM.D THEORYTIME TABLEFOR VIRTUALCLASSES

ZOOM LICENSE - 4

Days

IIIPharm.D

L

U

N

C

H

IIIPharm.D 9-9.45am 10-10.45am 11-11.45am 12-12.45pm 2-2.45pm 3 -3.45pm 4-4.45pm

Mon PA(Test) MC PF PF(Test)

-

-

- (JSK) (BG) (RS) (RS)

Tue PT-II PF PA PC-II

-

-

- (GKS) (RS) (JSK) (JS)

Wed PT-II MC PA PC-II PJ PT-II MC(Test) (GKS) (BG) (JSK) (JS) (CK) (GKS) (BG)

Thu PC-II MC PA PC-II(Test)

(JS)

-

-

- (JS) (BG) (JSK)

Fri PJ

-

-

-

-

-

- (CK)

Sat PJ (Test)

-

-

PT-II (Test)

(GKS)

-

-

- (CK)

Pharmacology-II PharmaceuticalAnalysis

Pharmacotherapeutics-

PharmaceuticalJurisprudence (PJ)

MedicinalChemistry (MC)

PharmaceuticalFormulations (PF)

-Dr.J.Saravanan(JS) -Dr.J.S.K.Nagarajan(JSK)

-Dr.G.K.Sadagoban (GKS) -Dr.C.Keerthana(CK)

-Dr.B.Gowramma(BG)

-Dr.R.Sureshkumar(RS)

Note:UploadpowerpointaspdflectureinJSSUONLINEportalbeforethelectureday.

Dr.G.K.SadagobanDr.K.P.Arun

Name& SignofClassTeacher(IIPharm.D)Name& SignofCourseCoordinator(Pharm.D)


(2020-21)

50

STUDENT SUPPORTSERVICES

Student

Services

Person/s

Responsible

Responsibilities

Principal

Dr. Dhanabal S

Palaniswamy

Making decisions on behalf of the faculty, staff, students and

alumni to achieve the stated mission and vision of the college.

Effectively organizing and allocating the human and financial

resources of the college to achieve the stated mission and vision

of thecollege.

Implementing and enforcing the policies of the College and the

university.

Representing and advocating on behalf of the faculty,staff,

students and alumni to the university.

Vice

Principal

Dr. Afzal A

Mohammed

Supervision, coordination and delivery of teaching

programs

Management of programs toimprovethe knowledge,

skill and attitude ofstaff

Responsibility for general discipline matters ofstudents

Centre for continuous learning for professional excellence

(CCLPE)

Contribute to the overall managementofthe college

Administrative

Officer

Mr.

BasavalingaDe

veru H K

Coordinating a range of functions, such as finance, human

resources and other support areas that contributes significantly to

the management function within thecollege.

Managing the delivery of a particular service or function (e.g.

finance, library, human resources,facilities)

Performing routine administrativeactivities

Providing basic physical and emotional care forstudents

Assisting with coordination and planning of student routines

Providing routine customer service tasks such as reception and

providing straightforward advice about thecollege

Providing routine support tasks with respect to college

maintenance

Coordinating the day to day routine operational

requirements of a collegeoffice

Assuming responsibilities for the general cleanlinessand

maintenance of the college

6. COMMITTEES FOR VARIOUS


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ACTIVITIES/RESPONSIBILITIES:

1

Academic Council Board

Principal (Chairman)

Dr S N Meyyanathan, Member Secretary

All HODs

1A

Post Graduate Studies

Dr B Gowramma (Coordinator)

Dr Afzal Azam

Dr M J N Chandrasekar

1B

Under Graduate Studies

Dr S Jubie (Coordinator)

I-IV B.Pharm Class Teachers

1C Pharm D Dr K P Arun (Coordinator)

I-VI Pharm D Class Teachers

1D D.Pharm DrAnandVijaykumar, Coordinator

Principal (Chief Superintendent)

2

Examination Section

Vice-Principal (Dy. Chief Superintendent)

Dr R Kalirajan

Dr S N Meyyanathan

Dr S Jubie

MrVishwas H N

Dr KVVS Narayana Reddy

Mr.GRamu

DrAneena Suresh

Dr Suresh Kumar R

Mr R Arun

3

Student Counseling

Dr R Vadivelan

Dr Afzal Azam

Dr K P Arun

DrKeerthana C

4

Library

Dr S Ponnusankar (Coordinator)

Mr C Jayakumar


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All HODs

5

Sports

Mr B Shivaramakrishnan (Coordinator)

Dr M R Jeyaprakash (Coordinator)

Dr V Senthil

Dr G N K Ganesh

Dr S Gomathy

DrAneena Suresh

6

Purchase

Principal (Chairman)

Dr Afzal Azam, Vice-Principal

All HoDs

MrBasavalingadevaru H K, A O I/c

Mr P Rajashekarappa

7 Research Dr Suresh Kumar, Director-Research

Dr K Gowthamarajan

Dr Afzal Azam

Dr M J N Chandrasekar

8

Higher Education, Competitive

Examinations/ Personality

Development Cell, English

Coaching

Dr A Justin (Coordinator)

Mr P Dhamodaran

Dr Rajesh Kumar

DrNagaswamyVenkatesh

MsDeepalakshmi

Mr R Arun

9

National Pharmacy Week

Celebrations

Dr R Vadivelan, President- IPANLB, (Chairman)

Dr N Jawahar, Vice-President

IPANLB, (Co-Chairman)

Dr GNK Ganesh, Secretary, IPANLB

Dr S Jubie, Joint Secretary

Dr R Kalirajan, Treasurer, IPANLB


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EC Members of IPA Nilgiris Local Branch

10

Industry Institution

Interaction Cell

Dr K Gowthamarajan (Coordinator)

Dr T K Praveen

Dr N Krishnaveni

Dr G N K Ganesh

Dr S Juibe

Mr B Babu

11

Placement

Mr J S K Nagarajan (Coordinator)

All HODs

12 Magazine (Pharmasaga /

College Day Celebrations)

All Staff of Pharmacy Practice, Pharmaceutical

Biotechnology & Pharmacognosy

13

Website Maintenance /

Computer / Internet /

Telephone Maintenance

Mr C Jayakumar, (Coordinator)

Dr P R AnandVijaykumar

Dr R Kalirajan

Dr Rajesh Kumar

Mr B Shivarama Krishna

Dr G K Sadagoban

14

Animal House

Dr R Vadivelan (Coordinator)

Dr T K Praveen

DrAnandVijaykumar

Dr A Justin

Mr B Shivarama Krishnan

15

NSS Activities

Mr B Babu, (Coordinator- NSS)

Dr V Senthil, (Joint Coordinator)

Dr R Vadivelan

Ms M Deepalakshmi

Dr K P Arun

Dr G K Sadagoban

Dr D NagasamyVenkatesh


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16 UG Project Coordination Dr R Suresh Kumar

Dr Rajesh Kumar

MrVishwas H N

17

Industrial Training &

Practice School

Dr T K Praveen(Coordinator Industrial Training)

Dr N Jawahar (Coordinator Practice School)

Dr M R Jeyaprakash

Dr R Suresh Kumar

DrNagaswamyVenkatesh

18

Hostel Review

Principal & Chief Warden (Chairman)

DrMd Afzal Azam, Vice-Principal & Deputy Chief

Warden

MrBasavalingadevaru H K, A O I/c, Resident Warden –

Boys Hostel

Dr K P Arun, Warden, Boys Hostel

Dr N Krishnaveni, Warden, Girls Hostel

19 International Students Cell Dr S Ponnusankar (Coordinator)

Dr D Raja

Mr J S K Nagarajan

Dr S Gomathy

Dr S Jubie

20 Alumni Association

Co-ordination Dr K P Arun (Coordinator)

Mr P Dhamodaran

Dr Ashish Wadhwani

Mr J S K Nagarajan

Dr V Senthil

Dr G K Sadagoban

21 Internal Compliants

Committee Inspector – B1 Police Station, Ooty

Dr B Gowramma

Dr N Krishnaveni

Dr T K Praveen


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MsRoopa

DrKhayatiMoudgil

MsNiveshna, NGO Member

22 Internal Quality Assurance

Cell (IQAC) Dr K P Arun (Coordinator)

Dr Ashish Wadhwani (Deputy Coordinator)

Dr G N K Ganesh

Dr S Jubie

Dr Justin

Dr R Rajeshkumar

Dr M R Jeyaprakash

Ms B S Roopa

MsDeepalakshmi

23 Education / Admission Cell Dr M J N Chandrasekar (Coordinator)

Dr G N K Ganesh (Joint Coordinator)

Dr B Gowramma

Mr H N Vishwas

Mr G Ramu

Mr B Babu

Dr S Gomathy

DrKeerthana C

DrAneena Suresh

Mr R Arun

24 ISO Certification Mr J S K Nagarajan, Management Representative

Dr A Justin

Dr R Suresh Kumar

Dr M R Jeyaprakash

Dr R Rajeshkumar

Mr P Dhamodaran

Dr Swathi Swaroopa


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25 Rotaract Club Mr J S K Nagarajan (Coordinator)

26 Smart Campus

(Swachh Bharat) Principal (Chairman)

Vice-Principal (Co-Chairman)

MrBasavalingadevaru H K A O I/c

DrKhayatiMoudgil (Coordinator)

Dr Ashish Wadhwani (Deputy Coordinator)

Dr MJN Chandrasekar

Dr K P Arun

MrGurumallappa

Dr N Krishnaveni

Dr B Gowramma

Dr D NagasamyVenkatesh

MrShylendra Kumar

Mr K N Shivakumar

MrDivyashankar

Mr G S Manjunatha

Mr K Shivakumar

Mr R Shanthakumar

27 Spektrum Wall Magazine Mr B Shivarama Krishnan (Coordinator)

Mr KVVS Narayana Reddy

DrKhayatiMoudgil

Dr C Keerthana

Mr R Arun

28 Student Services Dr M R Jeyaprakash (Coordinator)

Mr B Babu

Mr M Deepalakshmi

Dr Ashish Wadhwani

DrKhayatiMoudgil

29 Event Management MrBasavalingadevaru H K, A O I/c (Coordinator)


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MrGurumallappa

Mr P Rajashekarappa

Electricians & Drivers

30 CPE Program Dr S Ponnusankar

Dr P R AnandVijayakumar

Dr A Justin

31 Statutory Approvals Mr P Dhamodaran

Dr S Jubie

Dr P R AnandVijayakumar

Ms Mary SagayeeSabistina

32 Red Cross Society &

Blood Donation

Mr.GRamu (Program Officer)

Mrs.MDeepalakshmi (Program Officer)

Dr.Keerthana C (Coordinator)

33 Program Committee Dr R Vadivelan

MrVishwas H N

DrKeerthana C

34 PG Diploma (Coordinator) Dr B Gowramma

35 Certificate Course

(Coordinator)

Dr N Jawahar

36 Course Coordinators

D.Pharm

DrAnandVijaykumar

B.Pharm Dr S Jubie

Pharm D Dr K P Arun

M.Pharm Dr B Gowramma (Coordinator)

Pharmaceutics Dr V Senthil

Pharm. Chemistry Dr R Kalirajan

Pharmacognosy Dr B Duraiswamy


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Pharmacology Dr T K Praveen

Pharm. Analysis Mr J S K Nagarajan

Pharm. Biotechnology Dr R Rajesh Kumar

Pharmacy Practice DrAneena Suresh

Pharm. Quality Assurance Dr M R Jeyaprakash

Industrial Pharmacy Dr N Jawahar

Pharm. Regulatory Affairs Dr G N K Ganesh

37 Class Teachers

I D.Pharm Dr.Gomathy

II D.Pharm Dr.PR.AnandVijaya Kumar

I B.Pharm Dr.A.Justin

II B.Pharm Dr. Karri V Satyanarayana Reddy

III B.Pharm Dr. V. Senthil

IV B.Pharm Dr. N. Jawahar

I Pharm.D Mr.Saravanan

II Pharm.D Ms. M. Deepalakshmi

III Pharm.D Dr. GK. Sadagoban

IV Pharm.D Dr.Swathi Swaroopa

V Pharm.D Ms.Roopa.BS

8. RESPONSIBILITIES OF EACHCOMMITTEE

Education/Admissioncell:


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59

The cell is responsible to create awareness about the pharmacy education

andprofession.

The team will be actively participating in two way communication between aspiring

students, who would wish to take up pharmacy curriculum after10+2.

Provides complete information package about the various courses offered by the

institution, fee structure and admission process.

This cell facilitates and assists the university officials for the smooth and fair

conduct of entrance tests for getting the admission into various UG and PG

programs and in the selectionprocess.

Record Maintenance

Fee collection anddocuments.

Maintaining all the records of students, which include the completed application,

academic information, transcripts, andothers.

Maintaining confidentiality of student educationalrecords.

Residential facility

To frame policy for the smooth functioning of the hostels, messes and other

facilities within the hostel.

To ensure that no ragging takes place in the hostels and maintain a ragging freehostels.

To plan for upgradation of facilities in thehostels.

To ensure maintenance of discipline in and around thehostel.

Any other responsibility assigned by the principal/higherauthority.

Health Services

To ensure the access to the health care facilities as per therequirements.

To facilitate the access to the Government District Head Quarters Hospital, Ooty

for free health care checkup and freemedications.

Institutional Hostel Review Committee

They shall collectively carry out hostel rounds during the working hours of the

institution and if necessary even after the working hours to ensure that the student’s

amenities, dining, and mess needs and discipline aremaintained.

They shall review hostel income and expenditure every month and give report to

theprincipal and also thewarden.

They shall carry out random stock verification, and also annual verification of all

records, stocks,etc.,

They shall periodically assess the quality offood.

Purchase made for the various provisions and vegetables for the hostel shall be


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60

checked by them with regard to the quantity and quality of the material delivered

tothe hostel.

They shall receive the grievances, complaints, if any, regard to the ragging, theft,

etc., if any, from the students and redress them to the extentpossible.

Teaching & Learning

Students made aware of curriculum, syllabi, method of evaluation through

orientation programme in the beginning of the year. Academic calendar of events

(course-wise and subject wise for UG and PG courses), feedback and academic

planning is given to the students.

Unitized teaching plan to ensure proper teaching-learning transaction and

continuous evaluation in the form of internal assessmentexaminations.

Teaching-learning (TL) strategies include practical, field work, project work,

student seminars, group discussions, case studies, industrial/field visits, in-plant

training, along with didactic teaching.

ICT enabled TL process (Computers, Internet, LCD, Models,etc.).

The learner centric approach ensured through student seminars, assignments, project

work, visits, in-house trainingetc.

Faculty function as academic counselors andmentors.

Continuous internal assessment that is shared with students to ensure proper

understanding of the subject and clarification of doubts. Students are encouraged to

use extensively the library resources, computers and e-material in the TLprocess.

Mentoring

Monitor, evaluate and report student progress in key learningareas.

Implement strategies to achieve targets related to student learningoutcomes.

Maintain records of class attendance and recording studentprogress.

Supervisingarangeofstudentactivitiesincludingsupportandwelfareprogramsand

contributing to a range of co-curricular activities.

To send sessional marks statement and attendance to the parents after completion of

each sessional.

Maintain the student profile form which consists of bio - data of students, their

residential and permanent addresses, their academicgrades.

Any problem related to the particular student is attended by the respective Batch

teacher which includes counseling thestudents.

Examination section

Each of the college’s examinations falls under the responsibility of an examination


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61

coordinator.

Adhere to all rules and regulations pertaining to the conduct ofexaminations.

Adhere to timelines for the development, conduct and review ofexaminations.

To announce the date of sessional examination well in advance to the students

andstaff.

To collect the question paper from the individual subject teachers and maintain the

confidentiality of thesame.

To assign the invigilation duty to thestaffand ensure the smooth conducting of

theexam.

To check the seating arrangement of the students in the examinationhall

Extracurri

cular

activities

Sports:

Represent the views and interests of students on sporting matters to the University,

locally andnationally.

Encourage students to participatein recreational, intramural, and

performance sport along with fitness and wellbeingprogrammes.

Organize and support meetings of representatives of allclasses.

To develop and promote all areas of sport provided by thecollege.

Represent students of the university to local and national bodies and organizing

campaigns in support of student to promote health and social

awarenessprogrammes.

To identify the student coordinators for individual sport events well in advance for

the smooth conduction ofevents.

To carry out Annual athletic meet for two days in an academicyear.

The schedule of events is prepared and communicated to all staff and students by

displaying on the noticeboard.

Cultural & Literary:

A team consisting of principal, national pharmacy week celebrations (NPWC)

committee members and staff coordinators will decide the schedule, events, rules

and regulations of the NPWC.

To ensure the commencement of schedule of NPWC well inadvance.

To prepare the listof participants and event schedules in association with student

representatives.

Identify the judges for each event inadvance.

Encourage students to participate in inter-collegiate cultural events and coordinate

such programs.

Ensuring the discipline of the students during culturalprogram.


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62

National Service Scheme (NSS)

To provide NSS orientation to the students for social servicescheme.

To encourage the students for participation in various social serviceschemes.

To conduct NSS regular activities as per the NSS and universityguidelines.

To organize NSS annual special camp in a selectedvillage.

To conduct rallies for promotion of public health awareness.

Placement Cell

To look after the training and placement activities ofstudents.

To have close liaison with industry for placement ofstudents.

To work in consultation with Coordinator, Industry Institution Interaction Cell

(IIIC) for organizing lectures by the professionals fromindustry.

To collect feedback from the companies coming forplacement.

Arrange Training programmes for soft skills and for interview facing skills for the

students using institutional and externalexpertise.

To organize the entrepreneurship workshops.

Preparing the ‘Placement Brochure’ with the curriculum-vitae of outgoing students

of all the programs.

Industrial Training

Liaising with pharmaceutical industries for the training of B. Pharm Students in

IIIyear

Communicating and arranging industrial visits for thestudents

Maintaining all the track records of industrial training andvisits

Student Counseling

Providing counseling for the needy students on both professional and personal

related aspects.

Discuss with the mentors of individual students prior to counseling to get the

background information about thestudent.

Providing counseling to the parents on various issues related to their wards

whenever necessary.

IV Pharm D Curriculum & Lecture Plan (2020-21)

63

Arranging professional counselors based on the need to counsel students and

orparents.

Higher Education, Competitive Exams / Personality Development Program / English Coaching

Coordinating the personality developmentprograms.

Coordinating the coaching classes for competitive exams for higher studies with the

assistance of internal and external subjectexperts.

Coordinating English language coaching for the students especially who are from

Non- English speakingcountries.

International Students Services Cell

Facilitating the legal procedures and immigration issues of internationalstudents.

Liaising with the district police and administration for the verification process and

VISA proceedings.

Providing orientation towards the socio-cultural aspects of the country and college

to avoid conflicts during the period of theirstay.

Anti- Sexual Harassment Committee

Addressing the issues related to sexualharassment.

Recommending for necessary legal/ administrative actions against the persons if

proven guilty.

Social Discrimination Prevention Committee

Addressing the issues related to socialdiscrimination.

Recommending for necessary legal/ administrative actions against the persons if

proven guilty.

Spektrum:

Wall Magazine Committee

Coordinating with the student committees to explore the talents ofstudents.

Updating the wall magazine periodically and monitoring the performances of

thestudents.


64

9. GRIEVANCE REDRESSALCOMMITTEE

S. No. Name Position Contact No.

1. Dr. S P Dhanabal

Principal, JSS College of Pharmacy , Ooty Chairman 09489613428

2. Dr. Afzal A Mohammed

Vice Principal

Co-

Chairman 09486687029

3. Dr. M J N Chandrasekar

4. Dr. Arun K Parthasarathy

Assistant Professor

Department of Pharmacy Practice

09994934663

5. Dr. KrishnaveniNagappan

Hostel Warden

09442083447

6. Dr A Justin

Assistant Professor, Department

of Pharmacology

9942932150

10. ANTI – RAGGINGCOMMITTEE

As per the decision of the Hon’ble Supreme Court of India in writ petition No. (C) 656 / 1998,

“RAGGING IS PROHIBITED”. If an incident of ragging comes to the notice of the authority

concerned, the accused student(s) will be given an opportunity to explain and if the explanation

isnot satisfactory the authority will expel him / her from the institution. In this view, an anti –

ragging committee is constituted in our institution (as per the regulation notified by AICTE, New

Delhi vide F. NO. 37-3/Legal/IACTE/2009 dated July 1, 2009) with the following members. The

details of their names and telephone numbers are given here for your assistance. In case of any

untoward incidents pertaining to ragging must be immediately brought to the knowledge of the

members to curb ragging at its inception stageitself.

Anti -Ragging/ Disciplinary Committee

Name of the Staff Designation Mobile

Phone

Number

E-mail. i.d.

Dr. S.P. Dhanabal Principal &

Chief Warden

94890 44577 [email protected]

Inspector of Police,

B1 Police Station

Mr. H.K. Administrative 94890 44575 [email protected]




65

Basavalingadevaru Officer

&Residential

Warden(Boy’s

Hostel)

Dr. Arun K P Assistant

Professor

& Warden

(Boy’s Hostel)


Dr. N. Krishnaveni Professor

&

Warde

n

(Girl’sHostel)


Dr.R.Kalirajan

Dr. GNK Ganesh Assistant

Professor


Dr. M.R.

Jeyaprakash

Assistant

Professor


Dr.S.Gomathy Assistant

Professor

9486433876 [email protected]

Mr.R.Arun Lecturer 8903055696 [email protected]

Mr.HS.Kumar

Mr.SS.Umesh

Anti- Ragging/ Squad

Name of the Staff Designation Mobile

Phone

Number

E-mail. i.d.

Dr. Arun K P Assistant

Professor

& Warden

(Boy’s

Hostel)

99949

34663

[email protected]

Dr. N. Krishnaveni Professor

& Warden

(Girl’s Hostel)

94420

83447

[email protected]










66

Dr. V. Senthil Professor 98426

50602

[email protected]

Dr. GNK Ganesh Assistant

Professor

94421

91918

[email protected]

Ms.Roopa BS Assistant

Professor

99523

35392

[email protected]

Dr.Khayati

Moudgil

Assistant

Professor

9489238815 [email protected]

Mr.Shylendra

Kumar

Librarian 9943874574 [email protected]

SAY NO TO RAGGING – M





jss academy of higher education & research, mysore (deemed

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