karl fischer titration slide
TRANSCRIPT
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Faruk Hossen ID:20151109005
Karl Fischer Titration
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KF IntroductionReagents
KF InstrumentsTypes
Endpoint indication ApplicationsLimitations
TOPICS
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Karl Fischer titration is a classic titration method in analytical chemistry that uses coulometric or volumetric
titration to determine trace amounts of water in a sample.
INTRODUCTION
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Basic ingredients of KF reagents
* Iodine* Sulphur
dioxide* Buffer* Solvent
I2
SO2
ImidazoleMethanol
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Instruments of KF
*Drying tube*Cathode chamber*Sample injection cap*Detection electrode*Electrode analysis*Rotor*Drain cook*Anode chamber
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pH dependency
log K
pH
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KF titration methods
Coulometric KF titration
Iodine is generated in titration cell (anodic oxidation)
Volumetric KF titration
Working medium & titrant
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The main compartment of the titration cell contains the anode solution plus the analyte. 1.alcohol (ROH), 2.a base (B),3. SO2 4. I2. A typical alcohol that may be used is methanol or diethylene glycol monoethyl ether, and a common base is imidazole.
Coulometric Titration
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Volumetric titration The volumetric titration is based on the same principles as the coulometric titration except that the anode solution above now is used as the titrant solution. The titrant:1. an alcohol (ROH),2. base (B),3. SO2 4. a known concentration of I2.5. Pyridine has been used as the base in this case.
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Endpoint indication
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• in technical products
(oil, plastics and gases)• in cosmetic products • in pharmaceutical products• in food industry
Aplication of kf
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• The major disadvantage with solids is that the water has to be accessible.
• Easily brought into methanol solution.• KF is selective for water
Limitations
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