king edward medical university lahore....

KING EDWARD MEDICAL UNIVERSITY LAHORE. Faculty of Basic Sciences MBBS Program Curriculum Course Title: Cardiovascular System( CVS) CVS Module:

DURATION From 25.5.2015 To 20.6.2015 CONTACT HOURS Lectures 83 Hours + Practical 14 Hours+ PBL session 16hrs =99+14 Hours CREDIT HOURS 8 credit Hours TEACHING METHODOLOGIES lectures/Practical/ Tutorials/ SGD/Demonstrations/Dissection/ PBL Break : daily half an hour break. PBL sessions � 1st part of the session one hour duration (general discussion of disease) � 2nd part of the session one hour duration (patient presentation and discussion) Topics for PBL � Hypertension � Ischemic heart disease angina pectoris � Myocardial Infarction � Left ventricular failure

� Circulatory shock � Raised intracranial pressure/ intracranial hemorrhage

Objectives: Upon completion of this course students should be able to: 1. Identify the anatomy of mediastinum, heart chambers, valves, great vessels and their distribution. 2. Describe the microscopic appearance of different parts of the cardiovascular system, normal embryological development with their common congenital abnormalities. 3. Describe and understand the anatomy and physiology of cardiac muscle, electrocardiogram ,cardiac cycle, hemodynamics, regulation of blood flow and blood pressure, microcirculations, and the mechanism of edema, cardiac failure and circulatory shock. 4- Explain the metabolism of the cardiac muscles and the value of the cardiac enzymes and their role in the diagnosis of acute myocardial disease. 5. Describe the role and types of lipoprotein disorders and the mechanism of formation of atherosclerosis. 6. Explain the characteristics of some of infection of cardiovascular system, endocarditics, myocarditis, pericardius, vasculitius. 7. Define the more common types of cardiovascular diseases with emphasis on etiology, mechanism, morphology and briefly to correlate the pathological aspects of diseases with clinical manifestations. 8. Understand the mechanisms of action, pharmacokinetics, uses and adverse effects of commonly used drugs in the treatment of cardiac failure, cardiac arrhythmias, hypertension, angina and drugs used in hyperlipidemias. 9. Identify and discuss the major cardiovascular risk factors in health and diseases. 10. Describe the nutritional and dietetic components in the etiology, management, and prevention of cardiovascular diseases.

3-Histological structure of valves and 3. Correlate the structure and functions of interventricular septum. sarcoplasmic reticulum, T tubules and formation of diad. 4.enumurate the components of intercalated disc.

Medicine Examination of CVS on patient or The students should be able to :- 1 hr/ OLD Bedside clinical methods

Departments Course content Duration / VENUE Recommended books/other

Learning outcomes . time/Teachin sources

g Method

Day 1 Monday 25.05.15

Anatomy General anatomy of CVS. The student should be able to enumerate 30 min / OLD Comprehensive principles of

Blood vascular system various divisions of circulatory system. 8.00- AUDITORIUM general Anatomy by Dr.

Dr Suhail Lymphatic system Classify vessels and describe function of each 8.30am/ Ghulam Ahmad.

Systemic pulmonary and portal type.define types of portal circulations.define Lecture General Anatomy By Dr.

circulation and identify fluid types and their site of Tassaduq Hussain

CSF, peri& endo lymphatic formation and drainage.

Aqueous humor, synovial fluid

Anatomy Anastomosis and their types The student should be able to:- 45 min/ OLD Comprehensive principles of

End arteries and their 1. Define types of arterial and venous 8.30-9.15/ AUDITORIUM general Anatomy by Dr.

Dr Suhail significance. anastomosis,identify location where Lecture Ghulam Ahmad.

they are presentand explain their General Anatomy By Dr.

significance. Tassaduq Hussain

Physiology . Overview of CVS. The students should be able to:- 1 hr / OLD Text book of Physiology by

Functions of each part of CVS.Blood 1. Describe the systemic and pulmonary 9.15-10.15/

AUDITORIUM

Guyton & Hall

Dr M Shahid Saeed flow distribution,blood pressures in circulation and their differences. Lecture Review of Physiology by

different vessels,blood volume and C/S 2. Explain the functional parts of CVS. Ganong.

area to velocity relation .Receptors and 3. Discuss blood volume and pressure in

neurotransmitters acting on CVS different parts of CVS.

4. Describe the blood velocity and flow

through different parts of CVS and its

relation to cross sectional area.

5. Discuss the basic functions of CVS.

BREAK 10.15-10.45

Histology Heart. The Students must :- 45 min/ OLD Basic Histology by

Dr Mahjabeen 1-Histology of epicardium, 1. identify the histological structure of layers 10.45-11.30/ AUDITORIUM Junquierra

myocardium and endocardium of the heart Lecture

Functional Histology by

2-Light and electron microscopic 2.explain the light and E/M features of cardiac Wheater

features of cardiac muscle Muscle

Dr M Naeem Afzal EMW subject. 1-To inspect palpate, percuss auscultate the 11.30-12.30/ AUDITORIUM precordium. Lecture

2-To distinguish the normal heart sound. 3-To differentiate between normal heart sound and abnormal heart sounds. 4-To measure the JVP

Physiology Demonstration of Exposure of Frog,s Student should be able to dissect frogs by 2 hrs/ Physiology Practical book by Prof. M

Practical. Heart & Recording of NCG himself and exposure of heart and its 12.30-2.30/ & Biochem Labs Akram

Taken by

mounting on kymograph, Student should be able to Record Normal Cardiogram& Study the Effects Of Temp. practical

respective batch . teachers.

Day 2 Tuesday 26.5.15

Histology Three layered structure of circulatory The student should be able to 1-enumerate 1 hr/ OLD AUDITORIUM Basic Histology by

Dr Mahjabeen system. three layers of circulatory system and describe 8.00-9.00am/ Junquierra Macroscopic anatomy of elastic their composition.2-role of myointimal cells Lecture . Functional Histology by

arteries,muscular Aa, in atherosclerosis 3-functions of endothelial Wheater arterioles,venules. cells. 4-tunica media and associated Difference between veins and arteries. collagenopathies.5-describe the histological structure of elastic and muscular arteries and differentiate between arteries and veins.

Gross Anatomy Gross anatomy of heart location of The student should be able to locate apex 1hr/ Anatomy DH Clinically oriented anatomy Demonstration. apex beat beat, its importance and different areas of 9.00- by KLM Taken by Anatomy of pericardium and its pericardium and their auscultation. 10.00am/ Anatomy regional and Batch teachers surface land mark’s Demo applied by RJ Last.

BREAK 10.00-10.30 Physiology Pericardium and pericardial fluid The student should be able to describe the 45 min/ OLD AUDITORIUM Text book of Physiology by Dr M Shahid Saeed important functions of pericardium and Guyton & Hall pericardial fluid.. 10.30-11.15/ Review of Physiology by Cardiology Pericardial effusion The student should be able to explain the 30min/ OLD AUDITORIUM Davidson’s principles and

Dr. M. Aftab Pericarditis. basis of pericarditis and its clinical 11.15-11.45/ practice of Medicine

Cardiac tamponade and its treatments manifestation. LGD

.

Community Medicine Epidemiology of CVS diseases Student should be able to describe the 45 min/ OLD AUDITORIUM

PARK,S Text Book Of Community Medicine

Dr M N Tabassum incidence, prevalence, and risk factors of CVS 11.45-

Diseases. 12.30pm/Lect

ure

Anatomy Layers of Pericardium. The student should be able to: 2hr/12.30- Anatomy Clinically oriented anatomy

Dissection Respective Batch Teachers Pericardial cavity and sinuses 1.enumerate pericardial layers 2.30pm/disse Dissection hall. by KLM

Blood and nerve supply of pericardium 2.describe oblique and transverse sinuses and ction. Snell’s clinical Anatomy.

Clinical anatomy of pericardium. importance.

3.describe pericarditis,pericardial

effusion,pericardial rub, cardiac tamponade,

pericardiocetesis.

Day 3 Wednesday 27.5.15

Gross anatomy External features of heart The students should be able to place heart in 1hr/ 8.00- Anatomy DH. Clinically oriented anatomy

Demonstration Surface, borders and chamber anatomical position.2-identify chambers of 9.00 am/ by KLM

Respective Batch Teachers placement.Interventricular and heart.3-describe formation of surface, borders. Demonstratio Snell’s clinical Anatomy.

interatrial grooves.Relation of various Mark surface anatomy of heart on cadavers n

surfaces. and living specimen.

Surface anatomy of heart.

Histology Structure and classification of The student should be able to 1-enumerate 1hr /9.00- OLD Basic Histology by

Dr Mahjabeen capillaries. types of capillaries continuous fenestrated 10.00 am/ AUDITORIUM Junquierra

Pericytes and their functions sinusoidal etc.,2-Formation of blood thymic Lecture Functional Histology by

and blood brain barrier. Wheater

BREAK 10.00-10.30 Harper’s Biochemistry 28th

Biochemistry

Metabolism of heart muscle

Students will know the special feature of

30min/10.30-

OLD

Dr Samia Naz metabolism of Glucose protein and fat in 11.00 AUDITORIUM ed.

cardiac muscle and also will be able to am/lecture Lippincott’s illustrated

compare the metabolic feature in cardiac and reviews Biochemistry

skeletal muscle.

Physiology Physiology of heart muscle The student must be able to:- 1hr 15 OLD Text book of Physiology by

Dr Imrana Action potentials and refractory period 1. Explain the mechanism of min/11.00- AUDITORIUM Guyton & Hall

and state of excitability during this autorhythmicity and excitability. 12.15 Review of Physiology by

period. 2. Describe and draw action potential of pm/lecture Ganong nodes and muscle 3. Prepotential and effect of ANS on it.

Histology cardiac muscle and conducting system The student should be able to recognize and 2 hr/ HISTO LAB Difoire atlas of Histology. Practical in 3 Batches of heart under the light microscope. draw cardiac muscle under the light 12.15-2.15pm PHYSIO LABs

Structure of intercalated discs. microscope. /practical. Anatomy Differentiate between skeletal and cardiac lecture theater. muscle under the light microscope in both longitudinal and cross section. Day 4 Thursday 28.5.15

Embryology Development of pericardium and early The student should be able to describe early 1hr 8.00— OLD The developing human Dr Zahra Haider development of heart. development of pericardium and blood 9.00 AUDITORIUM Moore and Persaub

1.angiogenesis 2.cardiogenic ield vessels. AM/lecture Lang Mans Medical 3.formation and position of heart tube. Under stand relation of cardiogenic field with Embryology 4.external shape of the heart 5.cardiac pericardial cavity. loop Describe the effect of folding on heart tube. 6.sinus venosus. Enumerate various parts of cardiac lopp and 7.molecular regulation of cardiac structures derived from it. development. Veins draining into sinus venosus and left to right shunting Inducing and inhibitory factors in heart development.

Gross Anatomy Internal features of the heart. The student should be able to describe the 45min Anatomy DH Clinically oriented anatomy Demonstration. Right and left atria and ventricles. formation and internal features of left and /9.00-9.45am by KLM Respective Inflow and outflow tracts. right atria and ventricles. /demonstratio Anatomy regional and batch teachers. IVS., fibrous skeleton of heart and Openings and features of medial wall of right n applied by R.J.Last.

valves. Atrium Conducting system Formation and closure of foramen ovale Auscultatory areas of heart. Inflow and outflow tract of ventricles Structure of valves, papillary muscle and chordae tendinae Membranous and muscular parts of IVS.location of conducting system. BREAK 9.45-10.15

Physiology Cardiac cycle and its events The student should be able to 1- draw and 1hr 30min Old auditorium Text book of Physiology by Dr Imrana define CC and enumerate its various phases. 10.15- Guyton & Hall

2-explain the pressure changes in aorta 11.45am Review of Physiology by

pulmonary artery left ventricle and right Lecture Ganong

ventricle and right atrium with clear

understanding of JVP’

3- volume changes in the ventricles like EDV

and ESV.

4-pressure-volume loop of LV.

5-Understand that turbulence and vibration of

blood and vessel walls produce heart sounds.

6-Correlate the electrical and mechanical

events during CC

Cardiology Concept of normal ECG and funny’s 1. The student should be able to know 45min/ Old auditorium Davidson’s principles and

Dr. Waseem Ahmad current. the normal ECG and causes of 11.45- practice of Medicine

Prolong and short P wave, prolong 12.30pm/lect

PR interval ST segment elevation and ure

tall tented T wave and U wave and

causes of axis deviation.

2. The student should know what

Funny’s current is, its role in

automaticity and control of heart rate.

Physiology Recording of normal cardiogram & Student Should be able to demonstrate the shifting of pace maker and vagal escape 2hr /12.30- PHYSIOLOGY Practical book by Prof.M

Practical . Effectsof Temp on Frog,s Heart 2.30 LABS Akram

Respective pm/practical PHYSIOLOGY

LECTURE

batch teachers.

THEATER

biochemistry

lab

Day 5 Friday 29.5.15

Embryology Development of CVS 2 The student should be ableto describe 1hr/ 8-9 am/ OLD The developing human

Dr Zahra Haider Internal specializations.Division of 1-fate of r and L venous valves lecture AUDITORIUM Moore and Persaub

Lang Mans Medical

atrioventricular canal.Formation of 2-formation and function of endocardial

Embryology

IAS.Septum primum and Cushions

secundum.Formation of right and left 3-partitioning of primordial atrium

atria.Formation of bulbar ridges and 4- development of R and L atria and

division of conus cordisinto Ventricles

infundibulum and aortic vestibule 5-formation of aorta and pulmonary trunk.

Gross Anatomy Blood and nerve supply of heart. Student should be able to describe 1 hr/ Anatomy DH

Clinically oriented anatomy

Demonstration in Respective Batches Coronary Aa,cardiac veins and 1-origin , course, branches, area of 9-10 am/

coronary sinus distribution of coronary Aa.2- Right demonstratio by KLM

Anatomy regional and

Arterial supply and venous drainage of dominance of heart. n

applied by R.J.Last.

heart. 3-underlying principles of CABG4- most

Cardiac plexus common sites of coronary artery occlusion4-

Angina pectoris and MI venous drainage of heart and coronary sinus.

BREAK 10-10.30

Physiology Conduction, normal and abnormal The studentsshould be able to explain:- 1hr 30min/ OLD Text book of Physiology by

pacemakers of heart. Contraction and 1.The normal conducting system in heart 10.30-12.00 AUDITORIUM Guyton & Hall

2-A-V nodal delay Review of Physiology by

its control. noon/lecture.

3.Excitation contraction coupling. Ganong

4.Explain the role of Na-K ATPase and Na-

Ca exchanger and use of digoxin as positive

Dr Imrana inotropic and –ve chronotropic agent.

5.Frank-Starling’s law of heart.

6.effect of ANS on contractility of heart.

7.Normal vectrogram during conduction of

cardiac AP.

Medicine Dr Fawad Randhawa Stokes- Adams syndrome, ventricular The student should be able to know the basis 30min / OLD Davidson’s principles and

escape beats. of stoke adam’s syndrome ventricular escape 12-12.30pm/ AUDITORIUM practice of Medicine

beats PVC’s. Lecture

Day 6 Saturday 30.5.15

Gross Anatomy Anatomy of Mediastinum superior. The student should be able to define 45min/ 8.15- Anatomy DH Clinically oriented anatomy

Demonstration Divisions boundries and contents of mediastinum, describe its divisions.describe 9.00 am/ by KLM


mediastinum. the contents and ralations of middle demonstratio


mediastinum. n

Physiology Normal ECG along with conduction The students should draw and describe the 1hr OLD Text book of Physiology by

Dr Amna Tahir Defects ECG paper ,its time and voltage 15min/9.00- AUDITORIUM Guyton & Hall

criteria,normal waves,segments and intervals 10.15 Review of Physiology by

Ganong

of ECG.ECG lead systems.Einthoven’s am/lecture

law.Calculate heart rate from ECG.

Classification of heart blocks.

BREAK 10.15-10.45 Cardiology Tachyrrythmias,determination of The student should be able to describe and 1hr/ Old auditorium Davidson’s principles and

Dr. Waseem normal cardiac axis and axis draw the basis of sinus tacchycardias, SVT 10.45- practice of Medicine

deviations. and ventricular tachycardias. And conditions 11.45am/

associated with axis deviation. Lecture

Embryology Development of CVS 2 The student should be able to:- 45min / Old The developing human

Dr Zahra Haider Congenital abnormalities of heart. Apply their knowledge of cardiac 11.45- auditorium.. Moore and Persaub

development to understand the basis of Lang Mans Medical

12.30pm/

commonly occurring congenital Embryology

Lecture

abnormalities.

Physiology Effects of Drugs on frog’s Heart 2hr/ Physiology

Practical batch

Student should demonstrate the effect of adrenaline, acetylchline, propranolol and

atropine on heart performance and describe its physiological basis.

12.30-2.30 labs and

teachers. pm/ theater.bioche

Practical mistry lab.

Day 7 Monday 1.6.15

Dissection. External and internal features of heart The student should be able to know the 45min/ Anatomy Clinically oriented anatomy

Respective structure of valves and their locations and 8-8.45 am/ dissection hall by KLM

batch teachers. functions and associated abnormalities. Lecture Anatomy regional and


Embryology Development of Vascular system 1 The students should be able to name the NO. 1hr/ 8.45- Old The developing human

Dr Zahra Haider and 2 of aortic arched and structures derived from 9.45 auditorium Moore and Persaub

Development of intraembryonic, them.The effect of asymmetric development am/lecture Lang Mans Medical

Embryology

Th

vitellineand placental of 6 aortic arch.Location of dorsal

Aorta.Distribution of branches of Aorta.Apply

networks.Development and fate of

this knowledge to understand commonly

aortic arches.development of dorsal

aorta and its branches. occurring congenital anamalies. PDA, Coarctation and other anomalies of vascular system

BREAK 9.45-10.15 Physiology Normal functions of valves, normal The student should be able to 1-describe the 1hr/ 10.15- Old Text book of Physiology by

Dr M Shahid Saeed heart sound, phonocardiogram physiological basis of normal and abnormal 11.15

auditorium Guyton & Hall

Review of Physiology by

heart sounds. 2- Features of s1,s2,s3 and s4. am/lecture

Ganong

3-Explain the physiological splitting of heart

sounds.

Valvular heart diseases auscultation of The student should be able to EXPLAIN THE 1hr / Old Davidson’s principles and

Medicine heart sounds location of precordial auscultatory areas and 11.15- auditorium practice of Medicine

Dr Uzma Malik conditions associated with valvular heart 12.15pm/

diseases. Lecture

Histology Elastic & muscular arteries The student should be able to:- 2hr / Histology lab Difoire atlas of Histology

Practical Respective Batches 1. Identify the layers and draw elastic and 12.15-2-15 physiology

muscular arteries under light pm/ labs .

microscope. Practical Anatomy lec

2. Differentiate between the two arteries theater.

under the light microscope.


Gross anatomy Mediastinum Anterior and Posterior The students should be able to apply their 1hr/ Anatomy hall The developing human

Demonstration knowledge of cardiac development to 8-9 am/ Moore and Persaub

Respective Batches understand basis of commonly occurring Demonstratio Lang Mans Medical

Embryology

congenital anomalies. n

Cardiac surgery Treatment of congenital diseases The students should know :- 30min/ Old

1. The basis of treatment of VSD, ASD 9.00- auditorium

Dr. Aftab Younas and PDA. 9.30am/

2. The principle steps in surgical Lecture

treatment.

Break 9.30-10.00

Physiology Pathophysiology of Arrhythmias and The students should be able to describe 1hr/ Old Text book of Physiology by

Dr Amna Tahir cardiac arrest increased automaticity, ectopic foci, circus 10.0-11.00 auditorium Guyton & Hall

movements as cause of cardiac arrhythmias. am/ Review of Physiology by

Ganong

Explain causes of cardiac arrest and its Lecture

treatment.

Cardiology Clinical presentation of arrhythmias The student should know about the clinical 1hr/ Old Davidson’s principles and

Dr. Asma Sharif and presentation on ECG along with and ECG presentation of supraventricular, 11.00-12.00 auditorium practice of Medicine

treatment tachycardia, ventricular tachycardia and atrial /

fibrillation. Lecture

Pharmacology Mechanism of action of anti The students should know to:- 30min/ Old Basis and clinical

Dr. Afzaal arrhythmic drugs 1. Describe the main features of the major 12.0-12.30 auditorium Pharmacology (Bertram G.

group of antiarrhythmic drugs. pm/ Katzung)

2. Describe mechanism of action of each Lippincott’s Illustrated

Lecture

group. Reviews of Pharmacology

3. Understand pharmacokinetics clinical uses

and side effects of these drugs.

Physiology Effect of inorganic ions on frog’s heart Student should demonstrate the effect of 2hr/ Physiology lab Practical book by

Practical Sodium, Potassium & Calcium ions 12.30-2.30 and lecture Prof.M.Akram

theater,

pm/

Practical

biochemistry

lab.


Physiology Concepts of preload, after load, stroke The students must be able to:- 2hr Old Text book of Physiology by

Dr Syed M Zubair volume, cardiac output and its

1. Define the cardiac output and cardiac 8.00-


index. Review of Physiology by

regulation and venous return 10.00am/

2. Factor affecting cardiac output. Ganong.

Lecture

3. Describe the role of right arterial

pressure mean circulatory filling

pressure.

4. To study the effect of in symphatic

activity and blood volume on cardiac

output.

Break 10.00-10.30 Medicine Heart failure and its type The student should know to differentiate 1hr/ Old Davidson’s principles and

Dr Dur M Khan between the causes, types and treatment of 10.30-11.30 auditorium practice of Medicine

preloaded, after loaded and pump failure. am/

Lecture

Pharmacology Drugs involved in treatment of CCF 1hr/ 11.30- Physiology Bertram G. Katzung

Dr. Fawad and their mechanism of action 12.30 pm/ lecture theater. Lippincott’s Illustrated

Lecture Reviews of Pharmacology

Physiology Examination of Precordium Student should be able to examine the Precordium 2hr / Physiology lab Practical book by.M.Akram

Practical Of the Given subject 12.30-2.30 and lecture

theater,

pm/

biochemistry

Practical

lab.

Day 10 Thursday 4.6.15

Clinical . 1 Hr 15 min / Old Clinical anatomy by KLM

Anatomy of 8.00-9.15 am/ auditorium and Snell.

CVS Dr Lubna Lecture

.

Pathology Endothelial derived factors. 1. The student should know about the 15 min / Old Robin’s pathology

Dr. Raana different factors and their mechanism of 9.15-9.30 auditorium

action. am/

2. The role of antagonist to endothelial

Lecture

derived growth factor in macular eye

degeneration

Physiology Physical principles of circulation. The students should:- 45 min / Old Text book of Physiology by

Dr Imrana Volume of blood in different part of 1. Study relationship between pressure, 9.30-10.15 auditorium Guyton & Hall

circulation measurement of blood flow and resistance.

am/ Lecture Review of Physiology by

2. Discuss the laminar and turbulent Gagnon

flow.

blood flow.

3. Understand method of measurement

of blood flow.Define blood

pressure and its standard unit.

4. Discuss the resistance of blood flow,

peripheral and pulmonary resistance and effect of hematocrit on vascular resistance.

Break 10.15-10.45 PBL Breathlessness (LVF/CCF) 2hr/ 10.45- Old

Medicine Dr Imran Mahfooz 12.45 auditorium Uploaded Material

pm/PBL

PBL Cardiology Dr. M. Aftab Myocardial infarction 2

2Hr/ 12.45 to 2.30 Old Uploaded Material

auditorium

Day 11 Friday 5.6.15

Physiology Vascular capacitance and 1. Describe the vascular distensability and 1hr/ Old Text book of Physiology by

Dr Imrana distensability, and arterial pulsation its difference in arteries and veins. 8-9 am/ auditorium Guyton & Hall

2. Study and understand laplace law. Review of Physiology by

Lecture

3. Discuss the vascular compliance and Gagnon

delayed compliance.

4. Describe arterial pressure pulsation and

transmission of pressure pulses to the

peripheral arteries.

5. Discuss the functions of the veins, venous

pressure, venous resistance, venous valve

and venous pump

Cardiology Abnormal pressure pulse contours Student should be able to compare normal 30 min Old Davidson’s principles and

Dr. Naveed pressure pulse with aortic regurgitation, /9-9.30 am/ auditorium practice of Medicine

aortic stenosis, PDA. Lecture.

Pathology Atherosclerosis The student should know the basis of 1hr/ Old Guyton’s and Ganong’s

Dr. Samina Atherosclerosis. 9.30-10.30 auditorium Physiology

am/

Lecture

Break 10.30-11.00

Medicine Dr Suhail Bashir Ischemia heart disease (IHD) and its The student should know about the clinical 1hr/ Old Davidson’s principles and

treatment presentation and treatment of IHV. 11.00-12.00 auditorium practice of Medicine

/Lecture

Pharmacology Drugs involved in treatment of 30min / Old Basis and clinical

Dr. Afzal ischemia and their mechanism of 12-12.30. auditorium Pharmacology (Bertram G.

action pm/ Katzung)

Lippincott’s Illustrated

Lecture

Reviews of Pharmacology

Day 12 Saturday 6.6.2015 Physiology Veins and their functions venous Student should know the function of veins 1hr/8-9 Old Text book of Physiology by

Dr Syed Zubair pumps and their effects on venous and clinical importance of CVP. am/lecture auditorium Guyton & Hall


pressure. Central venous pressure.

Gagnon

Medicine Measurement of CVP and CVP line Student should know the indications of CVP 1hr / Old Uploaded material

Dr Adil Iqbal line. 9-10 am/ auditorium

Lecture

Break 10-10.30

General Surgery Phlebothrombosis and concepts of Student should know the clinical 1hr/ Old Uploaded material

Dr. Ameer varicose veins. manifestations of in these diseases and 10.30- auditorium

causes. 11.30am/

Lecture

Histology Arterioles veins and capillaries The students should be able to:- 2hr / Histology lab Difoire Atlas of Histology

Practical in Batches Light microscopic features of arterioles 1. Differentiate between arterioles 11.30-1.30 physiology

veins and capillaries. capillaries and vinuoles under light pm/ labs anatomy

micro scope and draw them. Practical lecture theater.

Tutorial Preparation till course covered. Student should be able to describe the 1.30-2.30 Physiology

Physiology. concepts covered at completion of 50% lecture

module theater,LABs

Respective

and

Teachers

biochemistry

lab.

Day 13 Monday 8.6.15

Anatomy. Radiology of CVS. The student should be able to read the 1hr/ Old Clinically oriented anatomy

Dr Lubna normal CXR relevant to CVS. 8-9 am/ auditorium by KLM


Lecture


Gross Anatomy Lymphatic drainage of thorax. The student should know the lymphatic 1hr / Anatomy DH Clinically oriented anatomy

Demonstration drainage. 9-10 am/

Demonstratio by KLM


n


Break 10.00-10.30 Physiology Microcirculation and its Student should be able to 1- Differentiate 1hr 15min/ Old Text book of Physiology by

Dr Zubair functions.Starlings forces and b//w interstitium and interstitial fluid.2- 10.30-11.45 auditorium Guyton & Hall

development of edema.edema safety Describe the mechanism of development of am/ Review of Physiology by

Gagnon

factor.causes of edema. edema.3-describe the starling forces and net Lecture

forces.

Pathology Exudates and transduate Differences and pathological diseases 30min/ Old

Dr. Raana associated 11.45-12.15 auditorium

pm/ Lecture.

Physiology Examination of radial pulse and study Student should be able to describe the radial 2hr / Physiology Practical book by

Practical the various characters of pulse. pulse in terms of rate, rhythm, volume, 12.30-2.30 labs and Prof.M.Akram

character, condition of vessel

pm/ theater.bioche

mistry lab.

wall,radiofemoral delayshould know the

Practical

pathophysiology of abnormal pulses.


Physiology Lymphatic system Student should know how lymphatics work 1hr 15min/ Old Text book of Physiology by

Dr Amna and there important role in drainage of fluid. 8-9.15 am/ auditorium Guyton & Hall


Lecture

Gagnon

Medicine Edema and its causes 1. The student should know about the 1hr/ Old Davidson’s principles and

Prof Dr Irshad Hussain edema due to decreased colloid 9.15-10.15 auditorium practice of Medicine

osmotic pressure and increased am/ hydrostatic pressure. Lecture 2. Clinical features of diseases associated with increased tissue fluid.

Break 10.15-10.45 Pathology Lymph-edema and lymphadenitis The students should know the C/F of 45 min / Old Uploaded lecture

Dr. Jalees lymphatic Filariasis and elephantiasis. 10.45- auditorium

11.30am/

Lecture

Pharmacology Role of diuretics and The student should know:- 1hr / Old Katzung’s pharmacology.

Dr. Riaz mineralocorticoid antagonist in edema 1. About the role and mechanism of 11.30-12.30 auditorium

and their mechanism of action. diuretics in edema. pm/

2. About the role and mechanism Lecture .

mineralocorticoid antagonist in

treatmentof edema.

PBL Medicine Postural Hypotension 1 HR ( Dr Bilquis) 12.30-1.30

Student should know the causes, treatment & Complications 2hr/

Old Auditorium Uploaded Material

12.30-

Raised Intra Cranial Pressure 1HR (Dr Athar Javaid) 1.30-2.30 2.30pm/


Physiology Local control of blood flow by tissues. Student should be able to explain the 1hr 15min/ Old Text book of Physiology by

Dr Zubair Effect of local metabolites. metabolic and nutrient demand theory of 8-9.15 am/ auditorium Guyton & Hall

Reactive and active hyperemias. blood flow control.(autoregulation). Lecture Review of Physiology by

Gagnon

Explain the long term blood flow control

(angiogenesis)

Pathology Dr. Hameed Thormboembolism,overview of 1. Should know the mechanism of 1hr / Old Robbins & Cotran Pathlogic

clotting cascade and platelet functions thrombosis and embolism and DVT. 9.15-10.15 auditorium basis of disease 8th ed

,virchow’s triad, hypercoagulation 2. Should know about the function of am/ states.brief view of DVT. macrophages. Lecture

Break 10.15-10.45 General surgery Peripheral vascular diseases Definition 45min/ Old Uploaded material

Clinical presentation with management. 10.45-11.30 auditorium

Dr. Ameer am/

Lecture

Pharmacology Anticoagulents and thrombolytics. Should know mach. Of action of drugs , 1hr/ Old Basis and clinical

Dr. Najam indications and contrindications’. 11.30-12.30 auditorium Pharmacology (Bertram G.

pm/ Katzung)


Lecture


Physiology Study of normal ECG and JVP

Student should be able to recognize different waves, segments and intervals of ECG and know the examination of Jugular Venous Pressure 2hr/ Physiology Practical physiology by

Practical 12.30-2.30 labs and M.Akram

pm/ lecture

Practical theater.bioch

emistry lab.

Day 16 Thursday 11.6.15

Surface Anat Demo in Respective Batches Embryology CVS 3 The students should be able to 1 Hour/ Old The developing human

Development of venous system 1.enumerate the fate of vitelline,umbilical 8-9 am/ auditorium Moore and Persaub

Langmans Medical

Anamolies of venous system and cardinal veins Lecture

Embryology

Fetal circulation and changes in 2.describe the steps involved in the shift of

circulation after birth.. originally symmetrical venous system to right

side.

Physiology Cerebral Circulation Student should be able to explain Physiological 30 min/ Old Text book of Physiology by

Dr Amna Basis of Cushing,s Reaction & Reflex Bradycardia 9.-9.30 auditorium Guyton & Hall

am/ Review of Physiology by

Gagnon

Lecture

Physiology Exercise Physiology of CVS

Should know 1. Types of Exercise 2. Basis of Exercise Physiology & Effect of Stress on Heart 3. Sympathetic Stimulation& Performance of Heart 4. TPR in Exercise 5. Responses of Intact & Transplanted Heart in Exercise 1 hr/ Old Davidson’s principles and

Dr Imrana 9.30-10.30am/ auditorium practice of Medicine

Lecture

Break 10.30-11.00 am

Pharmacolgy Role of Diuretics & Associated drugs in Lowering ICP

Students should know the mechanism of action, indications & Contraindications of ICP Lowering drugs

45 min 11.00 to 11.45 am/ Old

Dr. Riaz auditorium

Lecture

Neurosurgery Dr. Azam Niaz

Hydrocephalus& its Types. Role of shunting

Students should know the types of Hydrocephalus & Their Treatments

45 min 1145-12.30 Lecture Old Uploaded Material

auditorium

Cardiology

Left Ventricular Failure (1hr PBL) Dr. Asma / Dr. Tanvir

Students should know causes & treatment of LVF, 2hr /

Old Auditorium Uploaded Material

Exercise Tolerance Test (30 min Lect) Dr. Naveed

Students should know the indications& interpretation of ETT 12.30-1.30

(PBL)

1.30-2.00 Lect

DAY 17 Friday 12.6.15

Physiology Nervous regulation of blood Students should be able to describe the role 1hr .45 min/ Old

Text book of Physiology by

Dr. Amna Tahir pressure(ANS),reflex mechanism of

of baro and chemoreceptors in BP control. 8-9.45am/



blood pressure control.CNS ischemic

Describe the functions and components of Lecture

Gagnon

response. Cushing reaction vasomotor center

,Bainbridge and volume reflex, Baroreceptor reflex in detail

abdomen compression reflex . Different ranges of MAP in which these

reflexes are stimulated..

Break 9.45-10.15

Medicine Hypertension and its type Student should be able to describe the types 1hr/ Old Davidson’s principles and

Dr. Khalid Mehmood

and etiology of hypertention with dietry and 10.15-11.15 auditorium practice of Medicine

life style modifications to control am/

hypertention. Lecture

Gynecology and Pre-eclampsia and eclampsia 1-Students should know the about the 45min / Old Uploaded material

Obstetrics pathophysiology of pre-eclampsia and 11.15-12.00 / auditorium

eclampsia. lecture

Dr. Ahna Zia

2-Role of placental ischemia and release of vasoactive substances causing acute surg of BP and vasodilation due to failure of precappilaries sphinter leading to fits in eclampsia

PBL Raised intracranial pressure and Student should know causes, symptoms and 2hr / Old website

Medicine intracranial hemorrhage. treatment of intracranial hemorrhage 12.30-2.30 auditorium

Dr Mohsin Zaheer

pm/

PBL

Community Prevention of hypertension . 30 min / Old Uploaded material on

Medicine Dr M N Tabassum 12.00-12.30 / auditorium website

Lecture

DAY 18 Saturday 13.6.15

Physiology Renal control of blood pressure, role The student should explainthe renal-body 1hr.30 min/ Old Text book of Physiology by

Dr. Amna Tahir of ADH and aldosterone. fluid and renin angiotensin aldosterone 8-9.30 am/ auditorium Guyton & Hall

mechanisms of long term BP control and Lecture Review of medical

Physiology by Gagnon

Medicine/ Nephrology Chronic renal failure due to

Students should know the causes, treatment & Complications of CRF 45 min/ Old Davidson and uploaded

Dr M Anees hypertension. 9.30- auditorium lecture

10.15am/

Lecture

Break 10.15 -10.45

Ophthalmology Retinal changes in chronic 30 min / Old Uploaded material on

Dr. Ali Ayyaz hypertension. Students should know the retinal changes in Hypertension 10.45-11.15 auditorium website

am/

Lecture

Pharmacology Ant-hypertensive drugs. Students should know different classes 1hr.15 min/ Old katzung

Dr. Rubina mechanisms and contra indication of ant- 11.15-12.30 auditorium

hypertensive drugs. pm/

Lecture

DAY 19 Monday 15.6.15

clinical Anatomy Blood supply of heart Student should know coronary circulation 1hr/ Old Clinically oriented anatomy

Dr Suhail and concept of end arteries and their role in 8-9 am/ auditorium by KLM


infarction Lecture


Physiology Regulation of coronary circulation and Autonomic regulation of blood flow along 1hr/ Old Text book of Physiology by

Dr. S. M. Zubair effects of exercise with effect of different types of stress eg. 9-10 am/ auditorium Guyton & Hall


Exercise on heart and its blood flow Lecture

Gagnon

Break 10.00 -10.30

Cardiology MI and subendocardial infarction, Student must know sign and symptoms of 45min / Old Davidson’s principles and

Dr. Balquees angina and ECG correlation. IHD and its different types with ECG changes 10.30- auditorium practice of Medicine

11.15am/

Lecture

Pathology Events and stages in development of Pathology of MI and development of 30min/ Old Robbins & Cotran Pathlogic

Dr. Samina MI. atherosclerotic plaque 11.15- auditorium basis of disease 8th ed

11.45am/

Lecture

Pharmacology. Lipid lowering drugs and their mach. Concept of hyperlipidemia and role of drugs 45min/ Old Basis and clinical

Of action. in prevention of hyperlipidemic states and 11.45-12.30 / auditorium Pharmacology (Bertram G.

Katzung)

Dr. Nawaz syndromes associated with them. Lecture



Cardiac Surgery Coronary artery bypass. Types of CABAG and role of extracorporeal 30 min/ Old

Dr. Aftab circulation 12.30- 1.00pm auditorium

PBL cardiology Chest pain (Angina pectoris) 1.5hr/ Old website

dept 1.00-2.30 auditorium

.Dr. Balquees pm/

PBL


Biochemistry Concept of hyperlipidemias Metabolic Student should know the risk factors and 1 hr/ Old Lippincott

Dr Samia Naz syndromes associated with it. consequences of hyperlipidemia. the basis 8-9 am/ auditorium

of VLDL,LDL,HDL, and their associated risk Lecture

factors.

Pharmacology Anti- hyperlipidimic drugs Student should know the mech. Of action, 45 min/ Old Basis and clinical

indications and contra indication of anti- 9-9.45am/ auditorium Pharmacology (Bertram G.

Katzung)

Dr. Nawaz hyperlipidemic drugs. Lecture



Break 9.45-10.15

Pathology Fasting lipid profile and Pathology of Student should know the importance of 45 min/ Old Robbins & Cotran Pathlogic

Dr. Umar lipid storage diseases. Fasting lipid profile and importance of lipid 10.15-11.00 auditorium basis of disease 8th ed

storage diseases am/

Lecture

Medicine Treatment of hyperlipidimas and 45 min / Old

Dr Samar Firdous obesity 11.00- auditorium

11.45am/

Lecture

Community Prevention of Obesity 45 min Old

Medicine Dr M N Tabassum /11.45-12.30 auditorium

pm/lecture

Physiology Measurement of arterial BP by Student must be able to determine the blood 2 Hrs /12.30- Physiology Physiology practical book.

Practical palpatory and auscultatory methods. pressure of the given subject by palp and 2.00 labs, lecture

Effect of posture on blood pressure. auscult methods and determine the pm/Practical theater and

difference in lying sitting and standing biochemistry

positions. lab


Physiology Hypotension, Types of shock , and its Student should know neurogenic 1hr 30min/ 8- Old Text book of Physiology by

Dr Syed Zubair physiology ,hypovolemic and other types of shock 9.30 auditorium Guyton & Hall

am/lecture Review of Physiology by

Gagnon

Break 9.30-10.00

Pathology Pathology of all types of shock Pathologic manifestations of shock with 1hr 15min/ Old Robbins & Cotran Pathlogic

Dr. Hameed conditions associated. 10.00- auditorium basis of disease 8th ed

11.15am/

Lecture

Medicine Treatment of Therapies required in circulatory shock 1hr/ Old Davidson’s principles and

Dr Waseem cardiogenic,Anaphylactic, neurogenic management. 11.15- auditorium practice of Medicine

and septic shocks. 12.15am/

Lecture

General Surgery Treatment of hemorrhagic shock Students should know hypovolemic shock 15 Min/ Old Bailey and Love text book of

Dr. Ameer and how it present after trauma. 12.15-12.30/ auditorium surgery

Lecture

PBL General Circulatory shock 2hr / Old Bailey and Love text book of

surgery 12.30- auditorium surgery

Department 2.30pm/

PBL

Dr. Ameer

EVALUATION OF THE CVS MODULE. ON Thursday 18.6.2015 TIME 9.00am-12.00noon. TOTAL MARKS 100 PASS MARKS 50% TIME ALLOWED 55 MINUTES FOR MCQ’S 2 HRS FOR SEQ’S 10 SEQ’s of 5 mark each. 50 MCQ’S OF ONE BEST ANSWER TYPE OF 1 MARK EACH

NOTE: In case of any Holiday or change of venue the respective teachers will be informed by the Module Coordinator.

king edward medical university lahore....

Documents