knowledge systems lab jn 8/10/2002 fusion of multi-modality volumetric medical imagery mario aguilar...

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JN 8/10/2002 Knowledge Systems Lab Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS Department Jacksonville State University Jacksonville, AL 36265

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Knowledge Systems Lab JN 8/10/2002 Neurophysiologically Motivated Architecture

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Page 1: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

Fusion of Multi-Modality Volumetric Medical Imagery

Mario Aguilar and Joshua R. NewKnowledge Systems Laboratory

MCIS DepartmentJacksonville State University

Jacksonville, AL 36265

Page 2: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

Outline

• What is the neurophysiological motivation of the fusion architecture?

• How is fusion extended to a three-dimensional operator?

• How is this operator applied to volumetric data sets?

• What are the results?

Page 3: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

Neurophysiologically Motivated Architecture

Page 4: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

Fusion Architecture

Page 5: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

2D Image Fusion Example

GADPD

SPECTT2Color Fuse Result

Page 6: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

2D Image Fusion Animation

Page 7: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

Extensions to 3D

2D Fusion

ijS

sij

ijc

ijijij

IGxD

CIxBAxx

]*)[(

])[(

3D Fusion

Where:A – decay rateB – maximum activation level (set to 1)D – minimum activation level (set to 1)IC – excitatory inputIS – lateral inhibitory inputC and Gs are as follows:

2

22

2)(

2),(2

1

yx

yx eG

ijkS

sijk

ijkc

cijkijkijk

IGxD

IGCxBAxx

]*)[(

]*[)(

2

222

2)(

32),,(4

1

zyx

zyx eG

Where:A – decay rateB – maximum activation level (set to 1)D – minimum activation level (set to 1)IC – excitatory inputIS – lateral inhibitory inputC, Gc and Gs are as follows:

+-

2D Shunt Operator Symbol 3D Shunt Operator Symbol

Page 8: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

3D Fusion Architecture

T1Images

T2Images

R

G

B

ColorRemap

Color Fuse

Result

Noise cleaning &registration if needed

ContrastEnhancement

Between-band Fusionand Decorrelation

Page 9: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

3D Shunt ResultsOriginal 2D Shunt 3D Shunt

Page 10: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

3D Image Fusion Example

GADPD

SPECTT2

Page 11: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

3D Fusion Results• 3D Explorer Views – 3D vs. 2D shunt

Page 12: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

Conclusions

• Development of the 3D shunting operator is a natural extension of the 2D operator

• Application of the 3D shunting operator provides better definition of image details in volumetric data sets

• 3D fusion extensions developed in the context of Med-LIFE, a visualization and pattern recognition tool.

Page 13: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

FUSION SYSTEM EXTENSION2D Fusion

ijS

sij

ijc

ijijij

IGxD

CIxBAxx

]*)[(

])[(

3D FusionShunting Neural Network Equation:

Where:A – decay rateB – maximum activation level (set to 1)D – minimum activation level (set to 1)IC – excitatory inputIS – lateral inhibitory inputC and Gs are as follows:

2

22

2)(

2),(2

1

yx

yx eG

ijkS

sijk

ijkc

cijkijkijk

IGxD

IGCxBAxx

]*)[(

]*[)(

2

222

2)(

32),,(4

1

zyx

zyx eG

Shunting Neural Network Equation:

Where:A – decay rateB – maximum activation level (set to 1)D – minimum activation level (set to 1)IC – excitatory inputIS – lateral inhibitory inputC, Gc and Gs are as follows:

+-

2D Shunt Operator Symbol 3D Shunt Operator Symbol

Page 14: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

ResultsOriginal 2D Shunt 3D Shunt

Page 15: Knowledge Systems Lab JN 8/10/2002 Fusion of Multi-Modality Volumetric Medical Imagery Mario Aguilar and Joshua R. New Knowledge Systems Laboratory MCIS

JN 8/10/2002 Knowledge Systems Lab

AcknowledgementsThis work was supported by a Faculty Research Grant

awarded to the first author by the faculty research committee and Jacksonville State University. Opinions, interpretations, and conclusions are those of the authors and not necessarily endorsed by the committee or Jacksonville State University.

For additional information, please visit http://ksl.jsu.edu.