Lab animal welfare course Lab animal welfare course Working GroupWorking Group

CITI Program UpdateCITI Program Update

Meeting CDMeeting CD

L.A.W. Course ContentsL.A.W. Course Contents

1 Working with the IACUC Modules2 Essentials for IACUC Members Modules

3Post-Procedure Care of Mice and Rats in Research: Reducing Pain and Distress Modules

4 Aseptic Surgery Modules5 Antibody Production Modules6 Refresher Courses

1Working with Animals In Biomedical Research - Refresher Course Modules

2 Working with Cats in Research - Refresher Course7 The Responsible Conduct of Research with Laboratory Animals Modules

L.A.W. Course ContentsL.A.W. Course Contents

8 Species / Model Specific Courses1 Working with Amphibians in Research Settings Modules2 Working with Mice in Research Settings Modules3 Working with Rats in Research Settings Modules4 Working with Hamsters in Research Settings Modules5 Working with Gerbils in Research Settings Modules6 Working with Guinea Pigs in Research Settings Modules7 Working with Ferrets in Research Settings Modules8 Working with Rabbits in Research Settings Modules9 Working with Cats in Research Settings Modules

10 Working with Dogs in Research Settings Modules

11Working with the Laboratory Dog CD-ROM: Basic and Advanced Lessons Modules

12 Streaming Videotape (Video CD)- Working With the Laboratory Dog Modules13 Working with Swine in Research Settings Modules14 Working With Non-Human Primates in Research Settings Modules15 Streaming Videotape- Working Safely with Nonhuman Primates Modules

Old BusinessOld BusinessL.A.W. Course ContentL.A.W. Course Content

• Fish ModuleFish Module**– NOAA InvestigatorNOAA Investigator

• Field Studies ModuleField Studies Module

CITI Course Site Usage CITI Course Site Usage

10-1-200910-1-2009

CITI Program MembershipCITI Program Membership

Subscriber BreakdownSubscriber Breakdown

Category % Non-USUniversity 36% 3%Med. Center 18% 2%Veterans Affairs 14%HealthCare 7%Res, Institutes 7%Small Colleges 6%Government 6%Industry 3%Commercial IRB 2%CRO 1%

Professional Society <1%

2004 2005 2006 2007 2008 2009 20102004 2005 2006 2007 2008 2009 2010

9-2009*

Monthly Site UsageMonthly Site Usage

2004 2005 2006 2007 2008 2009 2010

New Learners/dayNew Learners/day

Courses completed per dayCourses completed per day

2004 2005 2006 2007 2008 2009 2010

Lab Animal Welfare Course Lab Animal Welfare Course Site UsageSite Usage

sites CRs CR per month % increase2009 311 42,807 4,506 32%2008 271 40,908 3,409

2009 CITI Course site usage 2009 CITI Course site usage Courses completedCourses completed

Course Year sites CRsCR per month

% increaseFrom 2008

LAW 2009 311 42,807 4,506 32%RCR 2009 222 23,361 2,596 65% GCP 2009 285 19005 2001 66%HIPS 2009 152 9301 979 52%HSR 2009 1324 352,664 37,122 22%Total 2009 1324 447138447138 47,067 33%

LAW Courses CompletedLAW Courses Completed10-1-200910-1-2009

Working with the IACUC 11692Working with Mice in Research 7657Working with Rats in Research Settings 4948Reducing Pain and Distress in Laboratory Mice and Rats 4361Working with the VA IACUC 3701Essentials for IACUC Members 2033Aseptic surgery 1250Institution specific, specialized courses 1411Working with Swine in Research Settings 1120Working with Rabbits in Research Settings 896

Working With Animals In Biomedical Research - Refresher Course 788Working with Amphibians in Research Settings 712Working with Nonhuman Primates in Research Settings 612Working with Dogs in Research 468Working with Guinea Pigs in Research Settings 362Working with Hamsters in Research Settings 318Working with Cats in Research Settings 269Working with Gerbils in Research Settings 208

All species specific courses completed 22,719

CITI Support StaffCITI Support Staff

Not shown Pablo Velascelo and Ryan Roelans

User Satisfaction Survey DataUser Satisfaction Survey Data

Data for September 2009Data for September 2009~440 responses~440 responses

Learner BreakdownLearner BreakdownLab Animal Welfare CourseLab Animal Welfare Course

IACUC Chair <1%IACUC Community Member <1%Institutional Official <1%Veterinary Technician <1%IACUC Coordinator 1%Animal Care Technician 2%IACUC Member 2%Masters Student 5%Co-investigator 8%Principle Investigator 11%Post-Doctoral Fellow 13%Ph.D. Student 13%Laboratory Research Staff 19%Undergraduate Student 25%

N=472

L.A.W. Courses completedL.A.W. Courses completed9-20099-2009

Working with Cats in a Research Setting 1%Working with Hamsters in a Research Setting 1%Working with Dogs in a Research Setting 1%Working with gerbils in a Research Setting 1%Working with Guinea Pigs in a Research Setting 2%Working with Amphibians in a Research Setting 2%Working with Swine in a Research Setting 2%Working with Rabbits in a Research Setting 2%Working with Non-Human Primates in a Research Setting 3%Special Module provided by your Institution 6%Minimizing Pain and Distress in Mice and Rats 7%Essentials for IACUC Members 8%Working with Rats in a Research Setting 12%Working with Mice in a Research Setting 19%Working with the IACUC 32%

N=917

GenderGender%

of R

espo

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s

It was easy to register and enroll in the appropriate It was easy to register and enroll in the appropriate course. course.

78%78%

Strongly agree Strongly disagree

% o

f Res

pond

ers

Course site navigation was easy and intuitive.Course site navigation was easy and intuitive.

79%79%

Strongly agree Strongly disagree

% o

f Res

pond

ers

The current course site presents the materials in a The current course site presents the materials in a way that is easy for me to understand and learnway that is easy for me to understand and learn

77%77%

n = 427

Strongly agree Strongly disagree

% o

f Res

pond

ers

Although training in Laboratory Animal Welfare issues is Although training in Laboratory Animal Welfare issues is mandated by the Federal government and by my institution, I mandated by the Federal government and by my institution, I

believe that this training is really believe that this training is really not very useful not very useful for new for new faculty and students?faculty and students?

N=435

Strongly agree Strongly disagree

% o

f Res

pond

ers

For this type of instruction, I would prefer a presentation model that For this type of instruction, I would prefer a presentation model that would require the learner to actively participate in games, videos or would require the learner to actively participate in games, videos or

other exercises designed to emphasize important concepts.other exercises designed to emphasize important concepts.

36%36%

Strongly agree Strongly disagree

% o

f Res

pond

ers

About how many hrs did it take you to complete About how many hrs did it take you to complete your Lab Animal Welfare Course requirements?your Lab Animal Welfare Course requirements?

% o

f Res

pond

ers

I think that the Internet is an appropriate tool to deliver basic I think that the Internet is an appropriate tool to deliver basic instruction in the ethical conduct of research with animal instruction in the ethical conduct of research with animal

subjects.subjects.

80%80%

Assuming a similar time commitment, would you Assuming a similar time commitment, would you prefer another vehicle for this mandated prefer another vehicle for this mandated

instruction? instruction?

N=437

% o

f Res

pond

ers

Does your institution rely exclusively on the Does your institution rely exclusively on the CITI Program to provide basic training in CITI Program to provide basic training in

Lab Animal Welfare? Lab Animal Welfare?

n = 435

% o

f Res

pond

ers

Scrolling through the content Scrolling through the content vsvs. click from "page to page“ . click from "page to page“ Please provide us with some feedback regarding the current Please provide us with some feedback regarding the current

presentation model. presentation model.

I DO NOT like the current presentation model another approach should be implemented. 3%

The "page to page" is better because I could pause and reflect on important points in the content. 5%

I prefer the "page to page" approach with interactive games or activities to break up the text. 6%

I DO NOT recommend the "Page to Page" model as it would increase the time to complete the course. 10%

The materials presented in the course are new to me. I like the current presentation model. 16%

I am familiar with the content. The current approach permits an efficient review of the material. 20%

The current approach enabled me to read through the content as if I where reading a book or journal. 40%

N=619

Now that I have completed the CITI Lab Animal Now that I have completed the CITI Lab Animal Welfare Course, I feel that the time I invested was Welfare Course, I feel that the time I invested was

time well spent.time well spent.

60%60%

Strongly agree Strongly disagree

% o

f Res

pond

ers

How do you rate the basic course, "Working With How do you rate the basic course, "Working With the IACUC", you just completed? the IACUC", you just completed?

66%66%

Poor Outstanding

N=391

% o

f Res

pond

ers

How do you rate the species / model specific How do you rate the species / model specific course you just completed? course you just completed?

67%67%

Poor Outstanding

N=279

% o

f Res

pond

ers

How do you rate the basic course, “Essentials for How do you rate the basic course, “Essentials for IACUC Members", you just completed? IACUC Members", you just completed?

58%58%

Poor Outstanding

N=243

% o

f Res

pond

ers

““An Experiment on a Bird in The Air Pump “ by Joseph Wright (1734-1797)An Experiment on a Bird in The Air Pump “ by Joseph Wright (1734-1797)British National Gallery- London British National Gallery- London

Joseph Wright (September 3, 1734 - August 29, 1797),

Software and hardware Software and hardware updates updates

New CITI HardwareNew CITI Hardware

• Hardware 8-10-2009 - ~$33KHardware 8-10-2009 - ~$33K– 4 new web servers4 new web servers– 2 new database servers. 2 new database servers. – 3Tb back up3Tb back up

CITI SoftwareCITI Software• Software update - Dr. Fallon and the VA software team Software update - Dr. Fallon and the VA software team

– Changes to the code and new hardware - 2,500 concurrent usersChanges to the code and new hardware - 2,500 concurrent users– Changes to the Learners Menu to be more user friendlyChanges to the Learners Menu to be more user friendly– ““Look Back” utility is now fully functionalLook Back” utility is now fully functional

• Institutions can give credit for modules completed previously at any time.Institutions can give credit for modules completed previously at any time.

– Installed: French, Russian and Thai language templates.Installed: French, Russian and Thai language templates.– Portal system fully implemented. Portal system fully implemented.

• 3 institutions are using the portal system, 3 institutions are using the portal system, • 6 more are interested and are in the test phase6 more are interested and are in the test phase

– Content and registrations and user data from Content and registrations and user data from www.IRBTraining.org is being transferred is being transferred to the to the www.CITIProgram.org platform. platform.

Experiences of Mentors and MenteesExperiences of Mentors and MenteesSurveySurvey

Paul Braunschweiger, Ph.D.Paul Braunschweiger, Ph.D.Ken Goodman, Ph.D.Ken Goodman, Ph.D.Sergio Litewka, MDSergio Litewka, MD

CITI ProgramCITI ProgramUniversity of Miami Ethics ProgramUniversity of Miami Ethics Program

The RCR Research SurveyThe RCR Research Survey

• Is provided to learner when the RCR Course Is provided to learner when the RCR Course is passed.is passed.

• Is approved by UM IRB.Is approved by UM IRB.• Is voluntary and anonymousIs voluntary and anonymous

– 2590 CITI RCR course completed per month.2590 CITI RCR course completed per month.– 787 voluntary RCR surveys submitted / month787 voluntary RCR surveys submitted / month– 29% Response rate.29% Response rate.

Working HypothesesWorking Hypotheses

• Although mentoring is crucial to the social and Although mentoring is crucial to the social and professional development of students and young professional development of students and young investigators, mentoring programs are not wide investigators, mentoring programs are not wide spread in academia.spread in academia.

• The role of Mentor and Research advisor is often The role of Mentor and Research advisor is often confused.confused.

• Many people who mentors may be ill prepared Many people who mentors may be ill prepared for the job. for the job.

Who are the study subjects?Who are the study subjects?

Research Integrity OfficerResearch Integrity Officer 1%1%Compliance CoordinatorCompliance Coordinator 1%1%Faculty MentorFaculty Mentor 2%2%Research AdvisorResearch Advisor 2%2%Research AdministratorResearch Administrator 5%5%Post-Doctoral FellowPost-Doctoral Fellow 5%5%Laboratory Research StaffLaboratory Research Staff 9%9%Ph.D. StudentPh.D. Student 15%15%Faculty InvestigatorFaculty Investigator 17%17%Masters StudentMasters Student 21%21%Undergraduate StudentUndergraduate Student 22%22%

n > 8900

Which course in the Responsible Which course in the Responsible Conduct of Research (RCR) did you Conduct of Research (RCR) did you

complete?complete?

The Social and Behavioral Sciences RCR Course 46%

The Biomedical Sciences RCR Course 37%

The Physical Sciences RCR Course 6%

The Humanities RCR Course. 6%

The RCR Course for Research Administrators 4%

I now plan to take a more active role in I now plan to take a more active role in promoting ethical research practices by: promoting ethical research practices by:

Add a research ethics module to my course.Add a research ethics module to my course. 9%9%Take an advanced research ethics course.Take an advanced research ethics course. 16%16%Encourage my institution to adopt RCR Encourage my institution to adopt RCR education.education. 16%16%Becoming a mentor.Becoming a mentor. 24%24%Attending more ethics related seminars.Attending more ethics related seminars. 34%34%Status quo – nothing moreStatus quo – nothing more 40%40%

If you DO NOT have a mentor at this time, choose If you DO NOT have a mentor at this time, choose all that apply to you.all that apply to you.

Mentoring was a rather unproductive experience.Mentoring was a rather unproductive experience. 5%5%I had a mentor early in my career. We don't communicate very much I had a mentor early in my career. We don't communicate very much any more.any more. 8%8%A mentor would be a waste of time at this point.A mentor would be a waste of time at this point. 9%9%I think that I have been missing out on a major resource. I intend to I think that I have been missing out on a major resource. I intend to find someone who can mentor me.find someone who can mentor me. 22%22%The module on mentoring helped me understand importance of The module on mentoring helped me understand importance of mentoring for scientists in training.mentoring for scientists in training. 56%56%

Please respond to the following statement. "My mentor has been Please respond to the following statement. "My mentor has been instrumental in providing the foundation to conduct research at the instrumental in providing the foundation to conduct research at the

highest ethical standard”.highest ethical standard”.

strongly disagree strongly agree

63%63%

13%13%

As a student or fellow, what research topics As a student or fellow, what research topics did you and your mentor discuss most did you and your mentor discuss most

frequently?frequently?

Responsible peer reviewResponsible peer review 5%*5%*Conflicts of InterestConflicts of Interest 6%6%Research misconductResearch misconduct 9%9%Responsible authorshipResponsible authorship 9%9%Collaborative ResearchCollaborative Research 14%14%Didn't discuss research ethicsDidn't discuss research ethics 25%25%Data acquisition and managementData acquisition and management 33%***33%***

*% Responders; n=4706; 59% of all responders

Which Res. ethics topic do you and your mentor Which Res. ethics topic do you and your mentor discuss? discuss? Didn't discuss research ethicsDidn't discuss research ethics

Data acquisition and management most frequent answer.Data acquisition and management most frequent answer.

% o

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As the MENTOR, which research ethics topic do As the MENTOR, which research ethics topic do you discuss most often with your trainees?you discuss most often with your trainees?

Lab animal welfare 4%Financial responsibility 4%Haven't discussed ethics very much. 5%Responsible peer review 9%Conflicts of interest 11%Research misconduct 12%Responsible authorship 12%Collaborative research 12%Human subjects protections 12%Data acquisition and management 19%

As As mentorsmentors what research ethics topic do you talk what research ethics topic do you talk about most with your mentees? about most with your mentees?

Research ethics were not discussed very much.Research ethics were not discussed very much.Most Frequent - Data Management

% o

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If you are mentoring students and post docs in If you are mentoring students and post docs in research ethics or the responsible conduct of research ethics or the responsible conduct of

research, what background do you have to teach research, what background do you have to teach these topics to students? these topics to students?

I have attended conferences on how to teach research ethics and the RCR to student and fellows. 3%*

I have attended seminars or conferences on research ethics. 12%*I have taken other courses in research ethics, and/or read about mentoring. 17%*

Many years of experience teaching and advising students. 18%I am now passing along to my students the wisdom I gained from my mentor. 18%

* = 32%n = 3551

Background to be a Mentor.Background to be a Mentor.conferences, seminars, courses on mentoringconferences, seminars, courses on mentoring

% o

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Sometimes the research advisor serves a dual role of mentor Sometimes the research advisor serves a dual role of mentor and research supervisorand research supervisor

Which choice most closely describes your situation.Which choice most closely describes your situation.

Is your mentor and res. advisor the same person?Is your mentor and res. advisor the same person?

YES!YES!%

of R

espo

nder

s

Assuming that a faculty-student mentor may require a skill set Assuming that a faculty-student mentor may require a skill set that is different from that of the research adviser, how well that is different from that of the research adviser, how well prepared do you think that you are to serve as an effective prepared do you think that you are to serve as an effective

mentor? mentor?

Poorly Prepared well prepared

Does your institution or organization have an official program Does your institution or organization have an official program specifically designed to match students and new faculty with specifically designed to match students and new faculty with

more senior level faculty interested in mentoring?more senior level faculty interested in mentoring?

Does your institution or organization have an official program Does your institution or organization have an official program specifically designed to match students and new faculty with specifically designed to match students and new faculty with

more senior level faculty interested in mentoring?more senior level faculty interested in mentoring?

I DON’T KNOW!I DON’T KNOW!

% o

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ConclusionsConclusions

• Data management is the most common research Data management is the most common research ethics topic discussed by mentors and mentees ethics topic discussed by mentors and mentees – 25% of students say discussions on research ethics with 25% of students say discussions on research ethics with

mentors are rare events.mentors are rare events.– Only 5% of mentors say that discussing research ethics Only 5% of mentors say that discussing research ethics

with students is a rare event.with students is a rare event.

• Rather low % of people who mentor students have Rather low % of people who mentor students have specific training.specific training.

ConclusionsConclusions

• For > 2/3 of students the mentor and res. advisor For > 2/3 of students the mentor and res. advisor are the same person.are the same person.

• Majority of survey subjects didn't know if their Majority of survey subjects didn't know if their institutions had a mentoring program.institutions had a mentoring program.– most pronounced in student groupsmost pronounced in student groups

SummarySummary• 32% growth for CITI-Lab Animal.32% growth for CITI-Lab Animal.• Excellent product that exceeds the federal mandate.Excellent product that exceeds the federal mandate.• Member institutions recognize the value of the program.Member institutions recognize the value of the program.• Learners recognize value of the program.Learners recognize value of the program.

• ConcernsConcerns– 40% of institutions use CITI exclusively.40% of institutions use CITI exclusively.– IACUC members course not rated as highly as others.IACUC members course not rated as highly as others.– We could / should take advantage of the survey tool to ask We could / should take advantage of the survey tool to ask

some questions about how learners interact with their IACUC.some questions about how learners interact with their IACUC.– Need to implement refresher courses before the next Need to implement refresher courses before the next

meeting. meeting.