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S.No. Name of the compound CAS Structure Remarks
001 1-(9H-carbazol-4-yloxy)-3-[2-(2-
methoxyphenoxy)ethylamino]propan-2-ol
C24H26N2O4
M.Wt.: 406.47
72956-09-3
Carvedilol
002 4-(oxiran-2-ylmethoxy)-9H-carbazole
C15H13NO2
M.Wt.: 239.27
51997-51-4
Carvedilol related compound
Carvedilol USP-D
003 1-(9H-carbazol-4-yloxy)-3-[2-(2-
methoxyphenoxy)ethyl-propan-2-
ylamino]propan-2-ol
C27H32 N2O4
M.Wt.: 448.5
1246819-01-1
N-Isopropyl Carvedilol
Carvedilol related compound
004 2-(2-methoxyphenoxy)ethanamine
C9H13NO2
M.Wt.: 167.21
1836-62-0
Carvedilol USP-A
005 1-[4-[2-hydroxy-3-[2-(2-
methoxyphenoxy)ethylamino]propoxy]car
bazol-9-yl]-3-[2-(2-
methoxyphenoxy)ethylamino]propan-2-ol
C36H43N3O7
M.Wt: : 629.74
1198090-73-1
Carvedilol USP-A
Carvedilol EP Impurity A
006 1-(9H-carbazol-4-yloxy)-3-[[3-(9H-
carbazol-4-yloxy)-2-hydroxypropyl]-[2-(2-
methoxyphenoxy)ethyl]amino]propan-2-ol
C39H39N3O6
M.Wt: 645.74
918903-20-5
Carvedilol USP-B
Carvedilol EP Impurity B
007 1-[benzyl-[2-(2-
methoxyphenoxy)ethyl]amino]-3-(9H-
carbazol-4-yloxy)propan-2-ol
C31H32N2O4
M.Wt. 496.60
72955-94-3
N-Benzyl Carvedilol
Carvedilol EP Impurity C;
Carvedilol Impurity C; Carvedilol
USP-C
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008
1-[9-[3-(9H-carbazol-4-yloxy)-2-
hydroxypropyl]carbazol-4-yl]oxy-3-[2-(2-
methoxyphenoxy)ethylamino]propan-2-ol
C39H39N3O6
M.Wt: 645.74
1391052-16-6
Carvedilol EP Impurity D
009 1-(9H-carbazol-4-yloxy)-3-[2-[2-[2-[[3-
(9H-carbazol-4-yloxy)-2-
hydroxypropyl]amino]ethoxy]phenoxy]eth
ylamino]propan-2-ol
C40H42N4O6
M.Wt.: 674.78
1346602-98-9
Carvedilol
Bisalkylpyrocatechol
Impurity
Carvedilol related compound
010 2-[2-(cyanomethoxy)phenoxy]acetonitrile 27165-64-6
Carvedilol impurity
011 2-[2-(cyanomethoxy)phenoxy]acetonitrile 27165-64-6
Carvedilol impurity
012 2-(5-methoxy-1H-indol-3-
yl)ethanamine;hydrochloride
Chemical Formula: C11H15ClN2O
MWt.: 226.70
66-83-1
Melatonin Related compound
013 N-[3-(2-formamido-5-methoxyphenyl)-3-
oxopropyl]acetamide
C13H16N2O4
MWt.: 264.28
52450-38-1
Melatonin degradant
014 4-ethyl-3-methyl-N-[2-[4-[(4-
methylcyclohexyl)carbamoylsulfamoyl]phe
nyl]ethyl]-5-oxo-2H-pyrrole-1-
carboxamide
C24H34N4O5S
684286-46-2
Glimepiride cis-isomer
Glimepiride EP Impurity A;
Glimepiride USP-A;
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MWt: 490.62
015 4-ethyl-3-methyl-5-oxo-N-[2-(4-
sulfamoylphenyl)ethyl]-2H-pyrrole-1-
carboxamide
C16H21N3O4S
MWt: 351.42
119018-29-0
Glimepiride sulfonamide
Glimepiride EP Impurity B;
Glimepiride USP-B;
016 Methyl N-[4-[2-[(4-ethyl-3-methyl-5-oxo-
2H-pyrrole-1-
carbonyl)amino]ethyl]phenyl]sulfonylcarb
amateC18H23N3O6S
MWt: 409.46
119018-30-3
Glimepiride urethane
Glimepiride EP Impurity C;
Glimepiride USP-C;
017 4-ethyl-3-methyl-N-[2-[3-[(4-
methylcyclohexyl)carbamoylsulfamoyl]phe
nyl]ethyl]-5-oxo-2H-pyrrole-1-
carboxamide
C24H34N4O5S
MWt: 490.62
791104-62-6
Glimepiride 3-isomer
Glimepiride EP Impurity D;
Glimepiride USP-D;
018 (2R,3S)-5-[3-(tert-butylamino)-2-
hydroxypropoxy]-1,2,3,4-
tetrahydronaphthalene-2,3-diol
C17H27NO4
MWt: 309.40
42200-33-9
Nadolol
019 cis-5-[(2RS)-2,3-Dihydroxypropoxy]-
1,2,3,4-tetrahydronaphtalene-2,3-diol
C13H18O5
MWt: 254.28
NA
Tetraol
Nadolol EP Impurity A; Nadolol
alcohol (USP)
020 cis-5-[(2RS)-2-Hydroxy-3-
methoxypropoxy]-
1,2,3,4-tetrahydronaphtalene-2,3-diol
C14H20O5
MWt: 268.31
NA
Nadolol EP Impurity B; Nadolol
Methoxy analog (USP)
021 5,5' -[(2-Hydroxypropane-1,3-diyl) NA Nadolol EP Impurity C;
Diaryl glycerol analog(USP)
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bis(oxy)]bis(cis-1,2,3,4-
tetrahydronaphthalene-2,3-diol)
C23H28O7
MWt: 416.46
022 5,5' [[(1,1-Dimethylethyl)imino]bis[(2-
hydroxypropane-1,3-diyl)oxy]]bis(cis-
1,2,3,4-tetrahydronaphthalene-2,3-diol)
C30H43NO8
M.Wt: 545.66
67247-26-1
Nadolol EP Impurity D Nadolol
dimer (USP)
023 cis-5-[(2-RS)-3-[(1,1-Dimethylethyl)
amino]-2-hydroxypropoxy]
-8-iodo-1,2,3,4-tetrahydronaphtalene-2,3-
diol
C17H26INO4
M.Wt: 435.3
67247-33-0
Nadolol EP Impurity E
024 1-(tert-butylamino)-3-naphthalen-1-
yloxypropan-2-ol
C17H23NO2
M.Wt: 273.4
2116-22-5
Nadolol EP Impurity F; Naphthyl
analoge(USP)
025 1-(tert-butylamino)-3-(5,6,7,8-
tetrahydronaphthalen-1-yloxy)propan-2-ol
C17H27NO2
M.Wt: 277.4
33841-03-1
De(2,3-dihydroxy)nadolol
Nadolol EP Impurity G;
Dideoxy Nadolol (USP)
026
5-(2-bromoethyl)-2,3-dihydro-1-
benzofuran
C10H11BrO
MWt: 227.10
127264-14-6
Darifenacin related compound
027 2,2-diphenyl-2-[(3S)-pyrrolidin-3-
yl]acetonitrile;hydrobromide
C18H19BrN2
MWt: 343.26
194602-27-2
Darifenacin related compound
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028 (2R,3R)-2,3-dihydroxybutanedioic
acid;2,2-diphenyl-2-[(3S)-pyrrolidin-3-
yl]acetamide C22H26N2O7
MWt: 430.45
134002-26-9
Darifenacin related compound
029 (S)-2-{1-[3-(2-Bromoethyl)-4-
hydroxyphenethyl]pyrrolidin-3-yl}-2,2-
diphenylacetamide
C28H31BrN2O2
MWt: 507.46
NA
Darifenacin related compound
030 (S)-2-[1-[2-(2,3-Dihydrobenzfuran-5-
yl)ethyl]-3-pyrrolidinyl]-2,2-diphenyl-N-
[2-(2,3-dihydrobenzfuran-5-
yl)ethyl]acetamide hydrobromide
C38H41BrN2O3
M.Wt: 653.65
:
NA
Darifenacin Dimer-2
impurity
Darifenacin related compound
031 (S)3-(2-Amino-2-oxo-1,1-diphenylethyl)-
1,1-bis(2-(2,3-dihydrobenzofuran-5-
yl)ethyl)pyrrolidin-1-ium bromide
C38H41BrN2O3
M Wt: 653.65
NA
Darifenacin Bis quaternary
ammonium salt
Darifenacin related compound
032 Methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-
hydroxy-4-methyloct-1-enyl]-5-
oxocyclopentyl]heptanoate C22H38O5
Molecular Weight: 382.53
59122-46-2
Misoprostol
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033 Methyl 7-[(1R,2S)-2-[(E)-4-hydroxy-4-
methyloct-1-enyl]-5-oxocyclopent-3-en-1-
yl]heptanoate C22H36O4
M.Wt.: 364.52
58682-86-3
Type-A misoprostol
Misoprostol EP Impurity C
034 Methyl 7-[2-[(E)-4-hydroxy-4-methyloct-
1-enyl]-5-oxocyclopenten-1-yl]heptanoate
C22H36O4
M.Wt.: 364.52
1331639-92-9
Type-B misoprostol
Misoprostol EP Impurity D
035 Methyl (1S*,2R*,3R*)-3-hydroxy-2-[(E)-
4-hydroxy-4-methyl-1-octenyl]-5-
oxocyclopentaneheptanoate
C22H38O5
M.Wt.: 382.53
NA
8-epi misoprostol
Misoprostol EP Impurity A
036
Methyl (1S*,2R*,3S*)-3-hydroxy-2-[(E)-
4-hydroxy-4-methyl-1-octenyl]-5-
oxocyclopentaneheptanoate
C22H38O5
M.Wt.: 382.53
NA
12-epi misoprostol
Misoprostol EP Impurity B
037
Methyl 7-[(1R,2R,3S)-3-hydroxy-2-[(E)-4-
hydroxy-4-methyloct-1-enyl]-5-
oxocyclopentyl]heptanoate
C22H38O5
M.Wt.: 382.53
58717-36-5
11-epi misoprostol
Misoprostol EP Impurity E
038 Methyl 7-(3-hydroxy-5-oxocyclopenten-1-
yl)heptanoate C13H20O4
M.Wt: 240.30
40098-26-8
Norprostol
Misoprostol EP impurity F
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039 (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-
[(E)-(3R)-3-hydroxy-3-methyloct-1-
enyl]cyclopentyl]-5-heptenoic acid.
C21H36O5
M.Wt.: 368.51
NA
15-epi Carboprost
040 (E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-
[(E)-(3S)-3-hydroxy-3-methyloct-1-
enyl]cyclopentyl]-5-heptenoic acid
C21H36O5
M.Wt,: 368.51
NA
trans-Carboprost
042
2-amino-2-(hydroxymethyl)propane-1,3-
diol
C4H11NO3
M.Wt.: 121.14
77-86-1
Tromethamine
043 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-
[(E,3S)-3-hydroxy-5-phenylpent-1-
enyl]cyclopentyl]hept-5-enoic acid
C23H32O5
Exact Mass: 388.22
38344-08-0
Bimatoprost S-Acid
044 (5Z)-7-((1R,2R,3R,5R)-3,5-dihydroxy-2-
((S,E)-3-hydroxy-5-phenylpent-1-
enyl)cyclopentyl)hept-5-enoic acid
C23H32O5
Exact Mass: 388.22
NA
Bimatoprost R-Acid
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045
15-Keto Bimatoprost
C25H35NO4
Exact Mass: 413.26
NA
15-Keto Bimatoprost
046 (5Z)-methyl 7-((1R,2R,3R,5S)-3,5-
dihydroxy-2-((S,E)-3-hydroxy-5-
phenylpent-1-enyl)cyclopentyl)hept-5-
enoate
C24H34O5
Exact Mass: 402.24
NA
Bimatoprost Acid
Methyl Ester
47 propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-
dihydroxy-2-[(E,3R)-3-hydroxy-5-
phenylpent-1-enyl]cyclopentyl]hept-5-
enoate
C26H38O5
M.Wt.: 430.58
130273-87-9
Bimatoprost isopropyl ester
48 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-
[(E,3R)-3-hydroxy-5-phenylpent-1-
enyl]cyclopentyl]-N-ethylhept-5-enamide
C25H37NO4
M.Wt.: 415.57
1163135-92-9
15-epi Bimatoprost ((15R)-
Bimatoprost)
49 ((E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-
[(E,3S)-3-hydroxy-5-phenylpent-1-
enyl]cyclopentyl]-N-ethylhept-5-enamide
C25H37NO4
M.Wt.: 415.57
1163135-95-2
5.6 TRANS- BIMATOPROST
IMPURITY
050
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-
[(E,3R)-3-hydroxy-4-[3-
(trifluoromethyl)phenoxy]but-1-
enyl]cyclopentyl]hept-5-enoic acid
C23H29F3O6
54276-17-4
Travoprost Acid
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Exact Mass: 458.19
051
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-
dihydroxy-2-[(E)-3-oxo-4-[3-
(trifluoromethyl)phenoxy]but-1-
enyl]cyclopentyl]hept-5-enoate
C26H33F3O6
Exact Mass: 498.53
404830-45-1
15-Keto Travoprost
052 2-(11-(3-(Dimethylamino)propylidene)-
6,11-dihydrodibenzo[b,e]oxepin-2-yl)-N-
methoxy-N-methylacetamide
C23H28N2O3
M. Wt.: 380.48
NA
Olopatadine impurity
053 2-[(11Z)-11-[3-
(dimethylamino)propylidene]-6H-
benzo[c][1]benzoxepin-2-yl]acetaldehyde
C21H24ClNO2
M.Wt.: 357.87
1376615-97-2
Olopatadine Carbaldehyde.
Hydrochloride
054 5-(Diphenylphosphoryl)pentanoic acid
C17H19O3P
M.Wt.: 302.30
71140-70-0
Latanoprost impurity
055 Methyl 5-(diphenylphosphoryl)pentanoate
C18H21O3P
M.Wt.: 316.33
146964-27-4
Latanoprost impurity
056 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-
[(3R)-3-hydroxy-5-
phenylpentyl]cyclopentyl]hept-5-enoic
acid
C23H34O5
Exact Mass: 390.24
41639-83-2
Latanoprost Acid
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057
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-
oxo-5-phenylpentyl)cyclopentyl]hept-5-
enoic acid C23H32O5
M.W. 388.51
369585-22-8
15-Keto Latanoprost Acid
058 5,6-trans-Latanoprost
C26H40O5
Exact Mass: 432.29
NA
5,6-trans-Latanoprost
059 propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-
dihydroxy-2-[(3S)-3-hydroxy-5-
phenylpentyl]cyclopentyl]hept-5-enoate
C26H40O5
Exact Mass: 432.29
145773-22-4
15(S)-Latanoprost
060
4,6-dichloro-2-methylsulfanylpyrimidine
C5H4Cl2N2S
M.Wt.: 195.07
6299-25-8
Alogliptin impurity
061
4,6-dichloro-2-methylsulfonylpyrimidine
C5H4Cl2N2O2S
M.Wt.: 227.07
4489-34-3
Alogliptin impurity
062 2-((4,6-Dichloropyrimidin-2-
yloxy)methyl)benzonitrile)
C12H7Cl2N3O
M.Wt.: 280.11
NA
Alogliptin impurity
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063 2-((4,6-Dimethoxypyrimidin-2-
yloxy)methyl)benzonitrile
C14H13N3O3
M.Wt.: 271.27
NA
Alogliptin impurity
064 2,2'-(((6-Chloropyrimidine-2,4-
diyl)bis(oxy))bis(methylene))dibenzonitrile
C20H13ClN4O2
M.Wt.: 376.80
NA
Alogliptin impurity
065 (6-Chloro-2-(methylthio)pyrimidin-4-ol)
C5H5ClN2OS
M.Wt.: 176.62
NA
Alogliptin impurity
066 2-[[5-methoxy-1-[4-
(trifluoromethyl)phenyl]pentylidene]amino
]oxyethanamine
C15H21F3N2O2
M.Wt.: 318.33
917096-37-8
Fluvoxamine impurity B
067
1-azabicyclo[2.2.2]octan-3-yl 2-hydroxy-
2,2-diphenylacetate
C21H23NO3
Exact Mass: 337.17
6581-06-2
Oxybutynin impurity
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068
methyl 2-hydroxy-2,2-diphenylacetate
C15H14O3
Exact Mass: 242.09
76-89-1
Oxybutynin impurity
069
4-(diethylamino)but-2-ynyl 2-hydroxy-
2,2-diphenylacetate
C22H25NO3
Exact Mass: 351.18
14943-53-4
Oxybutynin EP Impurity B
070
4-[ethyl(methyl)amino]but-2-ynyl 2-
cyclohexyl-2-hydroxy-2-phenylacetate
C22H31NO3
Exact Mass: 357.23
1199574-70-3
Oxybutynin Impurity C
071 Methyl 2-cyclohexyl-2-hydroxy-2-
phenylacetate
C15H20O3
Exact Mass: 248.14
10399-13-0
Oxybutynin Impurity 1
(Cyclohexyl Mandelic Acid Methyl
Ester)
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072
Ethyl 2-cyclohexyl-2-hydroxy-2-
phenylacetate C16H22O3
Exact Mass: 262.16
31197-69-0
Oxybutynin Impurity 2
(Phenylcyclohexylglycolic Acid
Ethyl Ester)
073
2-(1-cyanocyclohexyl)acetic acid
C9H13NO2
Exact Mass: 167.09
133481-09-1
Gabapentin impurity B
074
2-[1-[(3-oxo-2-azaspiro[4.5]decan-2-
yl)methyl]cyclohexyl]acetic acid
C18H29NO3
Exact Mass: 307.21
1076198-17-8
Gabapentin impurity D
075
2-(cyclohexanecarbonyloxy)acetic acid
C9H13NO2
Exact Mass: 167.09
667465-00-1
Gabapentin impurity E
076 2-(1-(2-aminoethyl)cyclohexyl)acetic acid
C10H19NO2
Exact Mass: 185.14
1500558-49-5
Gabapentin impurity G
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077
calcium;(3S,5R)-7-[2-(4-fluorophenyl)-3-
phenyl-4-(phenylcarbamoyl)-5-propan-2-
ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
C33H35FN2O5
Exact Mass 557.63
887196-25-0
Atorvastatin related compound
B
078
calcium;(3R,5R)-7-[2,3-bis(4-
fluorophenyl)-4-(phenylcarbamoyl)-5-
propan-2-ylpyrrol-1-yl]-3,5-
dihydroxyheptanoate
C33H33F2N2NaO5
Exact Mass: 597.61
693793-53-2
Atorvastatin Related compound
C.
079
4-[7-(4-fluorophenyl)-7-hydroxy-7a-
phenyl-1a-(phenylcarbamoyl)-1b-propan-
2-yl-4,5-dihydro-3H-
oxireno[1,2]pyrrolo[4,5-b][1,3]oxazin-3-
yl]-3-hydroxybutanoic acid;
C33H34FN2NaO7
Exact Mass: 612.22
1316291-19-6
Atorvastatin FXA Impurity
(Atorvastation epoxy
pyrrolooxazin 6-hydroxy analog
080 sodium;4-[1b-(4-fluorophenyl)-7-hydroxy-
1a-phenyl-7a-(phenylcarbamoyl)-7-
propan-2-yl-4,5-dihydro-3H-
oxireno[1,2]pyrrolo[3,5-b][1,3]oxazin-3-
yl]-3-hydroxybutanoate
C33H34FN2NaO7
Exact Mass: 612.22
1315629-79-8
NH
O
ON
OH
F
O
OH
ONa
O
Atorvastatin FX1 Impurity
(Atorvastation epoxy
pyrrolooxazin 7-hydroxy analog
081 5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-
hydroxy-6-oxooxan-2-yl]ethyl]-N,4-
diphenyl-2-propan-2-ylpyrrole-3-
carboxamide
C33H33FN2O4
Exact Mass: 540.24
125995-03-1
Atorvastatin related compound H
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082 4-(4-fluorophenyl)-2,4-dihydroxy-N,5-
diphenyl-2-propan-2-yl-3,6-
dioxabicyclo[3.1.0]hexane-1-carboxamide
C26H24FNO5
Exact Mass: 449.16
873950-19-7
Atorvastatin Epoxy
Tetrahydrofuran Analog
083 3-(4-fluorobenzoyl)-2-(2-methylpropyl)-
N,3-diphenyloxirane-2-carboxamide
C26H24FNO3
Exact Mass: 417.17
1246818-88-1
Atorvastatin Oxirane Impurity
084 Tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-
3-phenyl-4-(phenylcarbamoyl)-5-propan-
2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
C37H43FN2O5
Exact Mass: 614.32
134395-00-9
Atorvastatin tert-Butyl Ester
085
Bumetanide intermediate
C13H12N2O5S
Exact Mass: 308.05
NA
Bumetanide intermediate
086
3-(2-ethylhexylamino)-4-phenoxy-5-
sulfamoylbenzoic acid
C21H28N2O5S
Exact Mass: 420.17
153012-65-8
Bumetanide impurity
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087
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-
prop-1-en-2-yl-2-propyl-3-[[4-[2-(2H-
tetrazol-5-
yl)phenyl]phenyl]methyl]imidazole-4-
carboxylate C29H28N6O5
Exact mass: 540.21
879562-26-2 N
NNH
NN
NO
O
O
O
O
Olmesartan -EP impurity C
088 (2S)-2-(5-chloro-6-methoxynaphthalen-2-
yl)propanoic acid
C14H13ClO3
Exact Mass: 264.06
89617-86-7 O
Cl
(S)OH
O
Naproxen-EP-IMP-B
089
(2S)-2-(5-iodo-6-methoxynaphthalen-2-
yl)propanoic acid
C14H13IO3
Exact Mass: 355.99
116883-62-6
O
I
(S)OH
O
Naproxen-EP-IMP-D
090 (S)-2-(1-bromo-2-methoxynaphthalen-6-
yl)propanoic acid
C14H13BrO3
Exact Mass: 308
84236-26-0 O
Br
(S)OH
O
Naproxen-EP-IMP-C
091
(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-
dihydropyrrolo[2,3-d]pyrimidin-5-
yl)ethyl]benzoyl]amino]pentanedioic
acid;sodium
C20H21N5O6
Exact Mass: 427.15
937370-10-0
HN
N NH
O
H2N
NH
O
(R)
O
OH
O
OH
(D-Pemetrexed Disodium, EP
Imp. E
092 5-(Propylsulphanyl)-1H-benzimidazol-2-
amine
C10H13N3S
Exact Mass: 207.08
80983-36-4 N
HN
S
NH2
Albendazole EP Impurity A
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093 Methyl N-[5-propylsulfinyl)-1H-
benzo[d]imidazol-2-ylcarbamate
C12H15N3O3S
Exact Mass: 281.08
54029-12-8 N
HN
S
NH
O
O
O
Albendazole EP Impurity B
094 Methyl N-(5-propylsulfonyl)-1H-
benzo[d]imidazol-2-ylcarbamate
C12H15N3O4S
Exact Mass: 297.08
75184-71-3 N
HN
S
NH
O
O
O
O
Albendazole EP Impurity C
095
2-Amino-1H-benzimidazole-5-yl)propyl-
sulfanedione
C10H13N3O2S
Exact Mass: 239.07
80983-34-2 N
HN
S
NH2
O
O
Albendazole EP Impurity D
096
Methyl N(1H-benzo[d]imidazol-2-
yl)carbamate
C9H9N3O2
Exact Mass: 191.07
10605-21-7 N
HN
NH
O
O
Albendazole EP Impurity E
097
Methyl –N-5-(methylsulfanyl)-1H-
benzo[d]imidazol-2-ylcarbamate
C10H11N3O2S
Exact Mass: 237.06
80983-45-5 N
HN
S
NH
O
O
Albendazole EP Impurity F
(Under development)
098
Methyl N 5-chloro-1H-benzo[d]imidazol-2-
ylcarbamate
C9H8ClN3O2
Exact Mass: 225.03
N
HN
Cl
NH
O
O
Albendazole EP Impurity G
099 Methyl N 5-(2-methyl-4-oxopentan-2-
yl)sulfanyl-1H-benzo[d]imidazol-2-
ylcarbamate
C15H19N3O3S
Exact Mass: 321.11
NA
S
O
N
HN
NH
O
O
Albendazole EP Impurity H
(Under development)
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100 Methy N (5-propoxy-1H-benzo[d]imidazol-
2-ylcarbamate
C12H15N3O3
Exact Mass: 249.11
20559-55-1 N
HN
O
NH
O
O
Albendazole EP Impurity I
101
Methyl N 4,6-dichloro-1H-
benzo[d]imidazol-2-ylcarbamate
C9H7Cl2N3O2
Exact Mass: 258.99
946498-41-5 N
HN
NH
O
O
Cl
Cl
Albendazole EP Impurity J
102 Methyl N 5-(butyl sulfanyl)-1H-
benzo[d]imidazol-2-ylcarbamate
C13H17N3O2S
Exact Mass: 279.1
N
HN
S
NH
O
O
Albendazole EP Impurity K
103 Methyl N [5-(propane-2-yl)sulfanyl]-1H-
benzimidazol-2-yl] carbamate
C12H15N3O2S
Exact Mass: 265.09
108579-67-5 N
HN
S
NH
O
O
Albendazole EP Impurity L
(Under development)
104
Gabapentine in-house impurity
C13H21NO2
Exact Mass: 223.16
---
NO
O
Gabapentine inhouse impurity
105 Diclofenac impurity-A
C14H9Cl2NO
Exact Mass: 277.01
15362-40-0
Cl Cl
NO
Diclofenac impurity-A
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106
Olopatadine amide impurity (Z-isomer)
O
N
O
N
C23H28N2O2Exact Mass: 364.22
Olopatadine amide impurity (Z-
isomer)
107
Olopatadine isopropyl ester impurity (Z-
isomer)
O
N
O
O
C23H28N2O2Exact Mass: 364.22
Olopatadine isopropyl ester
impurity (Z-isomer)
108
Oxybutynin-EP-Impurity-C
1199574-70-3
HOO
ON
C21H29NO3Exact Mass: 343.21
Oxybutynin-EP-Impurity-C
109
Oxybutynin-EP-Impurity-E
1215677-72-7 HOO
ON
C23H33NO3Exact Mass: 371.25
Oxybutynin-EP-Impurity-E
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110
Escitolopram EP impurity-I
NOH
F
N
C20H21FN2OExact Mass: 324.16
Escitolopram EP impurity-I
111
N-methoxy-N-
methylcyclohexanecarboxamide
80783-98-8 N
O
O
C9H17NO2Exact Mass: 171.13
-----------
112
1-cyclohexylprop-2-en-1-one
------
O
C9H14OExact Mass: 138.1
----------------
113
Formetrol Impurity A
150513-24-9 NH2
HO
HN
OH
O
C18H24N2O3Exact Mass: 316.18
Formetrol Impurity A
114
Formetrol Impurity B
1224588-66-2
OH
NHCHO
HO
HN
O
C18H22N2O4Exact Mass: 330.16
Formetrol Impurity B
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115
15-S-Travoprost 1420791-14-5
O
OO
F
F
F
HO
OHHO
1420791-14-5
116
Carvedilol Propane diol
123119-89-1
NH
OOH
OH
Carvedilol Propane diol
117 Sorafenib impurity A
(IP2014)
284462-37-9 NH2
O
N
NH
O
C13H13N3O2Exact Mass: 243.1
Sorafenib impurity A
(IP2014)
118 Sorafenib impurity B
(IP2014)
NH
NH
OClCl
CF3F3C
1,3-bis(4-chloro-3-(trifluoromethyl)phenyl)urea
C15H8Cl2F6N2OExact Mass: 415.99
Sorafenib impurity B
(IP2014)
119
Sorafenib impurity C
(IP2014)
1431697-81-2
F3C
Cl HN
HN
O O
N
O
NH
C21H16ClF3N4O3Exact Mass: 464.09
Sorafenib impurity C
(IP2014)
120
Sorafenib related compound-15
284670-98-0
NH
NH
OO
N
NH
O
O
N
NH
O
C27H24N6O5Exact Mass: 512.18
Sorafenib related
compound-15
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121
Sorefenib impurity
( Under development)
2204442-52-2
NH
NH
OO
N
NH
O
O
N
O
O
C27H23N5O6Exact Mass: 513.16
Sorefenib impurity
( Under development)
122 Sorafenib Phenyl carbamate NH
OCl
F3C O
phenyl 4-chloro-3-(trifluoromethyl)phenylcarbamate
C14H9ClF3NO2Exact Mass: 315.03
Sorafenib Phenyl carbamate
123
Diclofenac isopropyl ester
66370-79-4
Cl
Cl
NH
O
O
C17H17Cl2NO2Exact Mass: 337.06
Diclofenac isopropyl ester
124 Tropicamide related compound A 33403-97-3 N
NH
C8H12N2Exact Mass: 136.1
Tropicamide related compound A
125 Tropicamide related compound D 103-82-2 OH
O
Tropicamide related compound D
126
Propofol EP impurity B
74926-89-9
Propofol EP impurity B
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127
Propofol EP impurity D
35946-91-9
Propofol EP impurity D
128
Propofol EP impurity E
2416-95-7
Propofol EP impurity E
129
Propofol EP impurity F
618-45-1
Propofol EP impurity F
130
Propofol EP impurity G
141214-18-8
Propofol EP impurity G
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131
Propofol EP impurity J
1988-11-0
Propofol EP impurity J
132
Propofol EP impurity K
14366-59-7
Propofol EP impurity K
133
Propofol EP impurity L
201166-22-5
Propofol EP impurity L
134
Propofol EP impurity O
74663-48-2
Propofol EP impurity O
135
Propofol EP impurity P
2095678-97-8
Propofol EP impurity P
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136
Propofol EP impurity N
13423-73-9
Propofol EP impurity N
137
1-{1-[4, 4-Bis (4-Fluorophenyl) but-3-en-
1-yl] piperidin-4-yl} benzimidazolin-2-one
NA
Pimozide olefin impurity
138
Diisopropylhomoveratrylcyanide
51698-54-5
Verapamil impurity
139
2-(3, 4—Dimethoxy-phenyl) 3-methyl-1-
but-2enenitrile
20850-47-9
Verapamil impurity
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140
2-(3,4-dimethoxyphenyl)-3-
methylbutanenitrile
Verapamil impurity
20850-49-1
Verapamil impurity
141
4-(3-nitrophenyl)morpholin-3-one
845729-43-3
4-(3-nitrophenyl)morpholin-3-
one
142 4-(3,5-dinitrophenyl) morpholin-3-one 2138262-09-4
4-(3,5-dinitrophenyl)
morpholin-3-one
143 N-(pyridin-2-ylmethyl)-2, 5-bis (2, 2, 2-
trifluoroethoxy) benzamide
57415-36-8
N-(pyridin-2-ylmethyl)-2, 5-bis (2,
2, 2-trifluoroethoxy) benzamide
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144
4-[4-[[[[4-Chloro-3-(trifluoromethyl)
phenyl] amino] carbonyl] amino] phenoxy]-
N-methyl-2- pyridinecarboxamide 1-Oxide
583840-03-3
Sorafenib N-Oxide
145
Phenyl (1H-pyrrol-1-yl) methanone
5145-65-3
N-benzoyl pyrrole
146
4-((7-chloroquinolin-4-yl)amino)-N-ethyl-N-
(2-hydroxyethyl)pentan-1-amine oxide
1449223-88-4
Hydroxy chloroquine Imp A
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147
Sodium 2-((4-((7-chloroquinolin-4-
yl)amino)pentyl)(ethyl)amino)ethyl sulfate
103152-84-7
( Free Acid)
Hydroxy chloroquine Imp B
148
2-((4-((7-chloroquinolin-4-
yl)amino)pentyl)amino)ethan-1-ol
4298-15-1
Hydroxy chloroquine Imp C
149
N4-(7-chloroquinolin-4-yl)-N1-
ethylpentane-1,4-diamine
1476-52-4
Hydroxy chloroquine Imp D
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150
4-((7-chloroquinolin-4-yl)amino)pentan-1-ol
10500-64-8
Hydroxy chloroquine Imp E
151
7-chloro-4-(2-methylpyrrolidin-1-
yl)quinoline
6281-58-9
Hydroxy chloroquine Imp F
152
4,7-dichloroquinoline
86-98-6
Hydroxy chloroquine Imp G
153
2-[[4-[(7-Chloro-4-quinolinyl) amino]
pentyl] ethylamino] ethanol 1-Acetate
47493-14-1
Hydroxy chloroquine O-Acetyl
impurity