lecture 6 organs tissues and organisms
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04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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bio 1.0
Online bioscience course for grades 6-12
Fall 2009
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Class mechanics…
• Attend the online Office Hour on Tuesdays at 3 PM via tokbox-Discuss previous week’s video lecture• Online video lecture e-mailed every Wednesday-view lecture and prepare to discuss the following Tuesday• Comment on video lecture using website discussion board• Online Final Exam given 12/9/2009
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Lecture 6: Organs, tissues and organisms
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Take Homes:
I. MulticellularityII. Organs and tissues: structure and compositionIII. Organs and tissues: genes determine structure and compositionIV. Differentiation and developmentV. Organisms
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Dictyostelium is attracted to cAMP:
http://www.dnatube.com/view_video.php?viewkey=217686ba124d7356686c
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Dictyostelium moves toward cAMPUsing its cytoskeleton:
http://dictybase.org/Multimedia/motility/motility.htm
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Dictyostelium as a model for single cells “going” multiclellular:
http://en.wikipedia.org/wiki/Dictyostelium
“stressed” founder cell secretes cAMP, inducing aggregation
Streaming spiral formation
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Dictyostelium single cells assemble Into a multicellular “slug”:
http://www.youtube.com/watch?v=518MhtVBJho
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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The evolutionary basis of multicellularity:
http://www.youtube.com/watch?v=JVqxyYBuI_U
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Take Home I
Organisms are collections of cells organized into tissues and organs…
Multicellularity
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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The worm Caenorhabditis elegans-700 cells make all of the tissues and organs:
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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The cells that make-up tissues and organs are specialized structurally and compositionally:
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Muscle Structure and Function:
http://www.youtube.com/watch?v=ren_IQPOhJc
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Three Types of Muscle:
http://www.youtube.com/watch?v=PJDrR3sZPZU
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Incredible Human Machine-knowledge on muscle & bone movement:
http://www.youtube.com/watch?v=7Rzi7zYlWno
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Take Home II
Organisms are made-up of many cells, which are made-up of many specialized proteins organized into specialized structures according to function…
Organs and tissues: structure and composition
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Various types of actin proteins form filaments in different types of muscle:
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Measuring RNA expression using Expressed Sequence Tags (ESTs):
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Actin gene mRNA expression in different types of muscle :
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Measuring protein expression using antibodies and tissue arrays:
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Actin protein expression in different muscle tissues:
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Take Home III
Differential expression of genes govern the protein structure, composition and thus function of cells in tissues and organs…
Organs and tissues: genes determine structure and composition
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Caenorhabditis elegans “fate map”:
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Tagging a gene with GFP:
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In the Beginning... There Was C. Elegans:
http://www.youtube.com/watch?v=M6_0zjEzF6g
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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Fluorescent C. elegans nervous system:
http://www.youtube.com/watch?v=LuBF6S6qKas
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Take Home IV
Tissues and organs form from the egg through the processes of cellular differentiation and development, both of which are controlled by genes…
Differentiation and development
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Genes program development:
http://www.youtube.com/watch?v=Oc4FAg2I_Z4
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Using our knowledge about genes and development to make a “dinochicken”:
http://www.youtube.com/watch?v=AeYhUUFDiF8
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Take Home V
The fundamental body plan and structure of an organism can be manipulated at the genetic level, and provides ways of testing ideas about evolution…
Organisms
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Next Week:
Physiology
How the cells in tissues and organs function to make organisms work…
04/10/23 Lecture 6: ORGANS TISSUES AND ORGANISMS
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instructorMark E Minie PhD